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Fine mapping of two recessive genes TaFLA1 and TaSPL8 controlling flag leaf angle in bread wheat
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作者 Qiushi Wang Jiaxing Bai +11 位作者 Hongchun Xiong Yongdun Xie Chaojie Wang Jiayu Gu Linshu Zhao Huiyuan Li Jinfeng Zhang Shirong Zhao Yuping Ding Zhengwu Fang Huijun Guo Luxiang Liu 《The Crop Journal》 SCIE CSCD 2024年第4期1159-1167,共9页
Flag leaf angle is one of the key target traits in high yield wheat breeding.A smaller flag leaf angle reduces shading and enables plants to grow at a higher density,which increases yield.Here we identified a mutant,j... Flag leaf angle is one of the key target traits in high yield wheat breeding.A smaller flag leaf angle reduces shading and enables plants to grow at a higher density,which increases yield.Here we identified a mutant,je0407,with an 84.34%-89.35%smaller flag leaf angle compared with the wild type.The mutant also had an abnormal lamina joint and no ligule or auricle.Genetic analysis indicated that the ligule was controlled by two recessive genes,which were mapped to chromosomes 2AS and 2DL.The mutant allele on chromosome 2AS was named Tafla1b,and it was fine mapped to a 1 Mb physical interval.The mutant allele on chr.2DL was identified as Taspl8b,a novel allele of TaSPL8 with a missense mutation in the second exon,which was used to develop a cleaved amplified polymorphic sequence marker.F3 and F4 lines derived from crosses between Jing411 and je0407 were genotyped to investigate interactions between the Tafla1b and Taspl8b alleles.Plants with the Tafla1b/Taspl8a genotype had 58.41%-82.76%smaller flag leaf angles,6.4%-24.9%shorter spikes,and a greater spikelet density(0.382 more spikelets per cm)compared with the wild type.Plants with the Tafla1a/Taspl8b genotype had 52.62%-82.24%smaller flag leaf angles and no differences in plant height or spikelet density compared with the wild type.Tafla1b/Taspl8b plants produced erect leaves with an abnormal lamina joint.The two alleles had dosage effects on ligule formation and flag leaf angle,but no significant effect on thousand-grain weight.The mutant alleles provide novel resources for improvement of wheat plant architecture. 展开更多
关键词 WHEAT Ligule flag leaf angle Fine mapping Tafla1 Taspl8
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An improved algorithm based on equivalent sound velocity profile method at large incident angle
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作者 Qianqian Li Qian Tong +3 位作者 Fanlin Yang Qi Li Zhihao Juan Yu Luo 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2024年第2期161-167,共7页
With the development of ultra-wide coverage technology,multibeam echo-sounder(MBES)system has put forward higher requirements for localization accuracy and computational efficiency of ray tracing method.The classical ... With the development of ultra-wide coverage technology,multibeam echo-sounder(MBES)system has put forward higher requirements for localization accuracy and computational efficiency of ray tracing method.The classical equivalent sound speed profile(ESSP)method replaces the measured sound velocity profile(SVP)with a simple constant gradient SVP,reducing the computational workload of beam positioning.However,in deep-sea environment,the depth measurement error of this method rapidly increases from the central beam to the edge beam.By analyzing the positioning error of the ESSP method at edge beam,it is discovered that the positioning error increases monotonically with the incident angle,and the relationship between them could be expressed by polynomial function.Therefore,an error correction algorithm based on polynomial fitting is obtained.The simulation experiment conducted on an inclined seafloor shows that the proposed algorithm exhibits comparable efficiency to the original ESSP method,while significantly improving bathymetry accuracy by nearly eight times in the edge beam. 展开更多
关键词 equivalent sound speed profile ray tracing method large incident angle edge beam deep sea error correction multibeam echo-sounder system
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Study on the optimal incident proton energy of ^(7)Li(p,n)^(7)Be neutron source for boron neutron capture therapy
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作者 Yi-Nan Zhu Zuo-Kang Lin +3 位作者 Hai-Yan Yu Ye Dai Zhi-Min Dai Xiao-Han Yu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第3期170-180,共11页
Boron neutron capture therapy(BNCT)is recognized as a precise binary targeted radiotherapy technique that effectively eliminates tumors through the^(10)B(n,α)^(7)Li nuclear reaction.Among various neutron sources,acce... Boron neutron capture therapy(BNCT)is recognized as a precise binary targeted radiotherapy technique that effectively eliminates tumors through the^(10)B(n,α)^(7)Li nuclear reaction.Among various neutron sources,accelerator-based sources have emerged as particularly promising for BNCT applications.The^(7)Li(p,n)^(7)Be reaction is highly regarded as a potential neutron source for BNCT,owing to its low threshold energy for the reaction,significant neutron yield,appropriate average neutron energy,and additional benefits.This study utilized Monte Carlo simulations to model the physical interactions within a lithium target subjected to proton bombardment,including neutron moderation by an MgF_(2)moderator and subsequent BNCT dose analysis using a Snyder head phantom.The study focused on calculating the yields of epithermal neutrons for various incident proton energies,finding an optimal energy at 2.7 MeV.Furthermore,the Snyder head phantom was employed in dose simulations to validate the effectiveness of this specific incident energy when utilizing a^(7)Li(p,n)^(7)Be neutron source for BNCT purposes. 展开更多
关键词 Boron neutron capture therapy ^(7)Li(p n)7Be neutron source incident proton energy Monte Carlo simulation
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SYSMEX XN-350血液分析仪检测儿童全血样本白细胞分类和Q-Flag标识准确性评估 被引量:1
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作者 周彩霞 张驰 夏涛 《现代检验医学杂志》 CAS 2023年第5期160-164,170,共6页
目的评估sysmex XN-350血液分析仪白细胞分类和Q-Flag标识在儿童全血标本检测中的准确性。方法收集2020年10月~2021年3月华中科技大学同济医学院附属同济医院124例0~12岁儿童静脉抗凝全血样本,分别进行仪器检测和涂片染色人工镜检分类。... 目的评估sysmex XN-350血液分析仪白细胞分类和Q-Flag标识在儿童全血标本检测中的准确性。方法收集2020年10月~2021年3月华中科技大学同济医学院附属同济医院124例0~12岁儿童静脉抗凝全血样本,分别进行仪器检测和涂片染色人工镜检分类。对XN-350白细胞分类及Q-Flag标识结果与镜检结果进行比较分析,评价仪器的准确性。结果两种方法的中性粒细胞、淋巴细胞、单核细胞、嗜酸性粒细胞和嗜碱性粒细胞相关系数分别为0.992,0.986,0.893,0.798和0.754(均P<0.001)。仪器各Q-Flag标识特异度较好(均>90%);除Left Shift(90.91%)较高外,其余参数敏感度较低。Left Shift,PLT Clump,NRBC,Aty Lymph和Blast/Abn Lymph的阴性预测值较好(均>85%)。Aty Lymph,PLT Clump和Blast/Abn Lymph的阳性预测值相对较佳,分别为79.41%,80.00%和75.33%。结论应用XN-350血液分析仪检测儿童样本时,白细胞分类结果可靠,是儿科门急诊首选的小型血液分析仪。而仪器Q-Flag的假阳性率较高,需对标识报警的样本进行必要的人工复检。 展开更多
关键词 XN-350血液分析仪 儿童 白细胞分类 Q-flag标识
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FLAG标签纳米抗体的筛选、表达及验证
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作者 王欣怡 王晓倩 +1 位作者 王红军 晁跃辉 《生物技术通报》 CAS CSCD 北大核心 2023年第10期323-331,共9页
纳米抗体是一种新型的蛋白质工程抗体,其体积小、稳定性强、亲和力高等特性为科学研究提供了新的可能性。FLAG标签是一种广泛应用于生物学研究中的短肽标签,在生物学研究中具有重要的作用。为了制备FLAG标签的纳米抗体,利用酵母双杂交... 纳米抗体是一种新型的蛋白质工程抗体,其体积小、稳定性强、亲和力高等特性为科学研究提供了新的可能性。FLAG标签是一种广泛应用于生物学研究中的短肽标签,在生物学研究中具有重要的作用。为了制备FLAG标签的纳米抗体,利用酵母双杂交技术筛选出具有高亲和力的纳米抗体,并对制备的FLAG纳米抗体进行性能检验。通过DNA重组技术,构建包含FLAG的诱饵载体,利用酵母双杂交技术,在驼源纳米抗体酵母文库中,筛选针对FLAG标签纳米抗体。在酵母文库中筛选出5个单一的候选抗体DNA序列,为了排除载体本身表达蛋白序列对抗体筛选带来的干扰,通过“点对点”验证方法排除非特异性杂交的可能,通过该操作确认所筛选的5株纳米抗体均能与FLAG标签发生特异性亲和反应。为了制备纳米抗体,构建了5个纳米抗体原核表达载体,并利用大肠杆菌体系进行表达。通过SDS-PAGE和Western杂交(WB)分析,结果显示,成功获得2株可溶性表达的抗FLAG标签蛋白纳米抗体。对这2株纳米抗体与商品化的常规FLAG标签抗体进行效果比对,结果显示制备的2株纳米抗体与商品化抗体均能够识别FLAG多肽及含有FLAG标签的融合蛋白,且在特异性上没有明显区别,表明制备的FLAG纳米抗体具有较好的应用前景。基于酵母双杂交技术,成功筛选并制备了FLAG标签纳米抗体,这一成果不仅丰富了纳米抗体的类型,也为抗体开发及应用提供了新的途径。该研究为进一步研究FLAG标签在生物学研究中的应用,以及纳米抗体在生物工程中的应用提供有力支持。 展开更多
关键词 flag标签 纳米抗体 酵母双杂 筛选 表达 特异性 免疫沉淀
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GNSS array receiver faced with overloaded interferences:anti-jamming performance and the incident directions of interferences 被引量:4
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作者 WANG Jie LIU Wenxiang +2 位作者 CHEN Feiqiang LU Zukun OU Gang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2023年第2期335-341,共7页
Anti-jamming solutions based on antenna arrays enhance the anti-jamming ability and the robustness of global navigation satellite system(GNSS)receiver remarkably.However,the performance of the receiver will deteriorat... Anti-jamming solutions based on antenna arrays enhance the anti-jamming ability and the robustness of global navigation satellite system(GNSS)receiver remarkably.However,the performance of the receiver will deteriorate significantly in the overloaded interferences scenario.We define the overloaded interferences scenario as where the number of interferences is more than or equal to the number of antenna arrays elements.In this paper,the effect mechanism of interferences with different incident directions is found by studying the anti-jamming performance of the adaptive space filter.The theoretical analysis and conclusions,which are first validated through numerical examples,reveal the relationships between the optimal weight vector and the eigenvectors of the input signal autocorrelation matrix,the relationships between the interference cancellation ratio(ICR),the signal to interference and noise power ratio(SINR)of the adaptive space filter output and the number of interferences,the eigenvalues of the input signal autocorrelation matrix.In addition,two simulation experiments are utilized to further corroborate the theoretical findings through soft anti-jamming receiver.The simulation results match well with the theoretical analysis results,thus validating the effect mechanism of overloaded interferences.The simulation results show that,for a four elements circular array,the performance difference is up to 19 dB with different incident directions of interferences.Anti-jamming performance evaluation and jamming deployment optimization can obtain more accurate and efficient results by using the conclusions. 展开更多
关键词 antenna arrays ANTI-JAMMING overloaded interferences incident direction
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C端带Flag标签重组小鼠IL-33慢病毒载体的构建及鉴定
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作者 高二可 张路 +1 位作者 徐旺旺 金齐力 《牡丹江医学院学报》 2023年第3期18-20,26,共4页
目的构建C端携带Flag标签蛋白的重组小鼠IL-33慢病毒表达载体,为进一步研究IL-33在肿瘤免疫中的作用提供实验基础。方法设计引物在小鼠IL-33基因的C端加入Flag标签,PCR法扩增带有标签的目的基因,再接入经酶切后的线性化pLVX-puro慢病毒... 目的构建C端携带Flag标签蛋白的重组小鼠IL-33慢病毒表达载体,为进一步研究IL-33在肿瘤免疫中的作用提供实验基础。方法设计引物在小鼠IL-33基因的C端加入Flag标签,PCR法扩增带有标签的目的基因,再接入经酶切后的线性化pLVX-puro慢病毒载体。带标签的目的基因重组载体用两种限制性内切酶ApaI和XhoI酶切后,进行琼脂糖凝胶电泳鉴定,最后测定目的基因序列。结果成功构建重组小鼠IL-33慢病毒表达载体并将Flag标签成功插入到目的基因的C端。结论成功构建了重组慢病毒表达载体pLVX-mIL-33-Flag,为下一步在肿瘤中研究IL-33的作用和机制奠定了基础。 展开更多
关键词 载体构建 flag标签 IL-33 肿瘤免疫
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XN1000-B4全自动血液分析仪Q-Flag报警在判断血小板聚集中的应用 被引量:1
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作者 张景逍 张晗钰 张金彪 《医疗装备》 2023年第18期90-94,共5页
目的根据XN1000-B4全自动血液分析仪中“PLT Clumps”的Q-Flag报警值判断低值血小板(PLT)结果的可靠性。方法通过对XN1000-B4全自动血液分析仪分析的低值PLT标本进行人工推片镜检,积累标本的Q-Flag报警值的分布及对应的PLT聚集情况,进... 目的根据XN1000-B4全自动血液分析仪中“PLT Clumps”的Q-Flag报警值判断低值血小板(PLT)结果的可靠性。方法通过对XN1000-B4全自动血液分析仪分析的低值PLT标本进行人工推片镜检,积累标本的Q-Flag报警值的分布及对应的PLT聚集情况,进行灵敏度和特异度分析并绘制ROC曲线。结果200份PLT聚集阳性标本的Q-Flag报警值分布于20~300之间。收集400份Q-Flag报警值>20的低值PLT标本进行人工推片镜检,结果显示,不同Q-Flag报警值分组的PLT聚集情况(阴性、阳性)比较,差异有统计学意义(χ^(2)=97.547,P=0.000);且随着Q-Flag报警值的增高,PLT聚集的阳性率增高,趋势性χ^(2)检验显示差异有统计学意义(趋势性χ^(2)=0.494,P=0.000);当Q-Flag报警值≥250时,PLT聚集阳性的灵敏度为95.0%。收集Q-Flag报警值<30的200份低值PLT标本进行人工推片镜检,结果显示,Q-Flag报警值<20时标本未发生PLT聚集的特异度为100.0%。ROC曲线提示,以Q-Flag报警值预测PLT聚集情况的最佳临界值为100,此时曲线下面积为0.900,灵敏度为86.5%,特异度为75.6%。结论通过XN1000-B4全自动血液分析仪“PLT Clumps”的Q-Flag报警值判断低值PLT标本是否发生PLT聚集具有较高的可行性,其应用不仅利于检验工作者提高工作效率,而且更好地保证了检验质量。 展开更多
关键词 Q-flag 低值血小板 血小板聚集 灵敏度 特异度
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Unmanned aerial vehicle based intelligent triage system in mass-casualty incidents using 5G and artificial intelligence 被引量:1
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作者 Jiafa Lu Xin Wang +7 位作者 Linghao Chen Xuedong Sun Rui Li Wanjing Zhong Yajing Fu Le Yang Weixiang Liu Wei Han 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2023年第4期273-279,共7页
BACKGROUND:Rapid on-site triage is critical after mass-casualty incidents(MCIs)and other mass injury events.Unmanned aerial vehicles(UAVs)have been used in MCIs to search and rescue wounded individuals,but they mainly... BACKGROUND:Rapid on-site triage is critical after mass-casualty incidents(MCIs)and other mass injury events.Unmanned aerial vehicles(UAVs)have been used in MCIs to search and rescue wounded individuals,but they mainly depend on the UAV operator’s experience.We used UAVs and artificial intelligence(AI)to provide a new technique for the triage of MCIs and more efficient solutions for emergency rescue.METHODS:This was a preliminary experimental study.We developed an intelligent triage system based on two AI algorithms,namely OpenPose and YOLO.Volunteers were recruited to simulate the MCI scene and triage,combined with UAV and Fifth Generation(5G)Mobile Communication Technology real-time transmission technique,to achieve triage in the simulated MCI scene.RESULTS:Seven postures were designed and recognized to achieve brief but meaningful triage in MCIs.Eight volunteers participated in the MCI simulation scenario.The results of simulation scenarios showed that the proposed method was feasible in tasks of triage for MCIs.CONCLUSION:The proposed technique may provide an alternative technique for the triage of MCIs and is an innovative method in emergency rescue. 展开更多
关键词 Mass-casualty incidents Emergency medical service Unmanned aerial vehicle Fifth Generation Mobile Communication Technology Artificial intelligence
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Traffic Incident Management Performance Measures: Ranking Agencies on Roadway Clearance Time 被引量:1
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作者 Maroa Mumtarin Skylar Knickerbocker +1 位作者 Theresa Litteral Jonathan S. Wood 《Journal of Transportation Technologies》 2023年第3期353-368,共16页
This study develops a procedure to rank agencies based on their incident responses using roadway clearance times for crashes. This analysis is not intended to grade agencies but to assist in identifying agencies requi... This study develops a procedure to rank agencies based on their incident responses using roadway clearance times for crashes. This analysis is not intended to grade agencies but to assist in identifying agencies requiring more training or resources for incident management. Previous NCHRP reports discussed usage of different factors including incident severity, roadway characteristics, number of lanes involved and time of incident separately for estimating the performance. However, it does not tell us how to incorporate all the factors at the same time. Thus, this study aims to account for multiple factors to ensure fair comparisons. This study used 149,174 crashes from Iowa that occurred from 2018 to 2021. A Tobit regression model was used to find the effect of different variables on roadway clearance time. Variables that cannot be controlled directly by agencies such as crash severity, roadway type, weather conditions, lighting conditions, etc., were included in the analysis as it helps to reduce bias in the ranking procedure. Then clearance time of each crash is normalized into a base condition using the regression coefficients. The normalization makes the process more efficient as the effect of uncontrollable factors has already been mitigated. Finally, the agencies were ranked by their average normalized roadway clearance time. This ranking process allows agencies to track their performance of previous crashes, can be used in identifying low performing agencies that could use additional resources and training, and can be used to identify high performing agencies to recognize for their efforts and performance. 展开更多
关键词 Traffic incident Management Roadway Clearance Time Performance Measures and Ranking Agency Performance Evaluation Tobit Regression Model
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RANDERS SPACES WITH SCALAR FLAG CURVATURE
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作者 李锦堂 《Acta Mathematica Scientia》 SCIE CSCD 2023年第3期994-1006,共13页
Let(M, F) be an n-dimensional Randers space with scalar flag curvature. In this paper, we will introduce the definition of a weak Einstein manifold. We can prove that if(M, F) is a weak Einstein manifold, then the fla... Let(M, F) be an n-dimensional Randers space with scalar flag curvature. In this paper, we will introduce the definition of a weak Einstein manifold. We can prove that if(M, F) is a weak Einstein manifold, then the flag curvature is constant. 展开更多
关键词 Randers spaces flag curvature sectional curvature weak Einstein manifold
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Methodology for Automatically Setting Camera View to Mile Marker for Traffic Incident Management
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作者 Jijo K. Mathew Haydn A. Malackowski +4 位作者 Christopher M. Gartner Jairaj Desai Edward D. Cox Ayman F. Habib Darcy M. Bullock 《Journal of Transportation Technologies》 2023年第4期708-730,共23页
Traffic incident management (TIM) is a FHWA Every Day Counts initiative with the objective of reducing secondary crashes, improving travel reliability, and ensuring safety of responders. Agency roadside cameras play a... Traffic incident management (TIM) is a FHWA Every Day Counts initiative with the objective of reducing secondary crashes, improving travel reliability, and ensuring safety of responders. Agency roadside cameras play a critical role in TIM by helping dispatchers quickly identify the precise location of incidents when receiving reports from motorists with varying levels of spatial accuracy. Reconciling position reports that are often mile marker based, with cameras that operate in a Pan-Tilt-Zoom coordinate system relies on dispatchers having detailed knowledge for hundreds of cameras and perhaps some presets. During real-time incident dispatching, reducing the time it takes to identify the most relevant cameras and setting their view on the incident is an important opportunity to improve incident management dispatch times. This research develops a camera-to-mile marker mapping technique that automatically sets the camera view to a specified mile marker within the field-of-view of the camera. Over 350 traffic cameras along Indiana’s 2250 directional miles of interstate were mapped to approximately 5000 discrete locations that correspond to approximately 780 directional miles (~35% of interstate) of camera coverage. This newly developed technique will allow operators to quickly identify the nearest camera and set them to the reported location. This research also identifies segments on the interstate system with limited or no camera coverage for decision makers to prioritize future capital investments. This paper concludes with brief discussion on future research to automate the mapping using LiDAR data and to set the cameras after automatically detecting the events using connected vehicle trajectory data. 展开更多
关键词 Roadside Cameras Traffic incident Management Connected Vehicles TRAJECTORY
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2015~2019年中国居民脑卒中发病与死亡特征分析 被引量:2
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作者 陈晓荣 颜流霞 +3 位作者 厚磊 蔡小宁 龙政 吴静 《中国循环杂志》 CSCD 北大核心 2024年第5期470-476,共7页
目的:分析2015~2019年中国居民脑卒中发病、死亡特征及其变化情况。方法:利用2014年在全国31个省级行政区100个县(市、区)建立的中国心脑血管事件登记系统中2015~2019年脑卒中发病和死亡数据,以监测地区常住人口为分母,计算年度脑卒中... 目的:分析2015~2019年中国居民脑卒中发病、死亡特征及其变化情况。方法:利用2014年在全国31个省级行政区100个县(市、区)建立的中国心脑血管事件登记系统中2015~2019年脑卒中发病和死亡数据,以监测地区常住人口为分母,计算年度脑卒中粗发病率;以第七次全国人口普查数据为标准人口,采用直接标化法计算年龄标化发病率;运用Joinpoint模型分析脑卒中发病率的年度变化百分比(APC)及变化趋势;以年度脑卒中病例的死亡数量(例)与报告发病数量(例)的比值计算死亡发病比。结果:2019年脑卒中粗发病率为468.48/10万,比2015年升高9.41%(APC=2.12%,95%CI:1.43%~2.82%,P_(trend)<0.01),且男性脑卒中粗发病率高于女性,农村高于城市。男性和女性的粗发病率分别升高11.26%(APC=2.53%,95%CI:1.83%~3.24%,P_(trend)<0.01)和7.26%(APC=1.63%,95%CI:0.81%~2.46%,P_(trend)<0.01)。2019年脑卒中年龄标化发病率为523.82/10万,比2015年下降7.47%(APC=-1.72%,95%CI:-3.23%~-0.20%,P_(trend)<0.05),女性脑卒中年龄标化发病率降低9.56%(APC=-2.27%,95%CI:-3.99%~-0.52%,P_(trend)<0.05),城市脑卒中年龄标化发病率降低13.19%(APC=-3.49%,95%CI:-5.34%~-1.61%,P_(trend)<0.05),城市女性脑卒中年龄标化发病率下降幅度(15.82%,APC=-4.27%,95%CI:-6.34%~-2.15%,P_(trend)<0.01)大于城市男性(11.40%,APC=-2.95%,95%CI:-4.56%~-1.31%,P_(trend)<0.05)。随着年龄的增长脑卒中粗发病率升高。相比2015年,2019年45~49岁年龄段的脑卒中粗发病率升高了12.48%(APC=3.18%,95%CI:1.67%~4.72%,P_(trend)<0.01),而80~84岁年龄段则降低15.76%(APC=-4.39%,95%CI:-7.63%~-1.04%,P_(trend)<0.05)。2015~2019年总体脑卒中死亡发病比为0.19。总体死亡发病比的年龄分布呈现“U”型,50~54岁及55~59岁人群的死亡发病比最低(0.10),之后随年龄增长逐渐升高,≥85岁最高(0.45),且各年龄段的城市死亡发病比均低于农村。结论:2015~2019年间监测地区脑卒中发病形势严峻,存在城乡、年龄、性别的差异化分布。未来有必要加强脑卒中防控,并在年龄、地区广泛覆盖等方面进一步优化。 展开更多
关键词 脑卒中 发病率 死亡率 流行病学
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一种具有flag板的自动化轨道吊大车定位装置及其应用探究
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作者 李文 《珠江水运》 2023年第20期56-58,共3页
目前自动化轨道吊堆场在使用期间会出现沉降或者凸起现象,轨道吊在大车行进期间会造成大车对射开关无法感应到flag板以及大车对射开关支架与flag板碰撞损坏的情况,通过安装可调式的flag板,可在堆场实际沉降或者凸起的地方对flag板进行... 目前自动化轨道吊堆场在使用期间会出现沉降或者凸起现象,轨道吊在大车行进期间会造成大车对射开关无法感应到flag板以及大车对射开关支架与flag板碰撞损坏的情况,通过安装可调式的flag板,可在堆场实际沉降或者凸起的地方对flag板进行高度的改变,以满足自动化轨道吊大车行走机构精准定位以及行进时实时位置校验,提高自动化轨道吊的作业效率。 展开更多
关键词 港口 轨道吊 flag 大车精准定位系统
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东芝进一步扩展Thermoflagger产品线
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《单片机与嵌入式系统应用》 2023年第11期95-95,共1页
东芝电子元件及存储装置株式会社(东芝)宣布,进一步扩展Thermoflagger过温检测IC产品线---“TCTH0xxxE系列”。该系列可用于具有正温度系数(PTC)热敏电阻的简单电路中,用来检测电子设备中的温度升高,六款新产品于今日开始支持批量出货... 东芝电子元件及存储装置株式会社(东芝)宣布,进一步扩展Thermoflagger过温检测IC产品线---“TCTH0xxxE系列”。该系列可用于具有正温度系数(PTC)热敏电阻的简单电路中,用来检测电子设备中的温度升高,六款新产品于今日开始支持批量出货。当配置在具有PTC热敏电阻(其电阻值随温度变化而变化)的简单电路中时,Thermoflagger过温检测IC不仅可以检测温度升高,还可以检测置于热源附近的PTC热敏电阻的电阻变化,并在温度过高时输出FLAG信号。例如,当Thermoflagger检测到异常发热情况并向MCU发送FLAG信号时,MCU将关闭设备或改变正在产热的设备或半导体的运行方式。通过串联PTC热敏电阻可同时在多个点进行过温检测。 展开更多
关键词 PTC热敏电阻 简单电路 存储装置 电阻变化 flag 电子设备 电子元件
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Teaching Intercultural Competence Using Critical Incident and Cultural Story Telling
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作者 LIU Sha 《Sino-US English Teaching》 2023年第3期101-105,共5页
Intercultural literacy is attached increasingly great importance in this interconnected world.People from diversified cultural backgrounds need to interact with each other for various purposes.Schools and organization... Intercultural literacy is attached increasingly great importance in this interconnected world.People from diversified cultural backgrounds need to interact with each other for various purposes.Schools and organizations offer courses to improve people’s intercultural competence.This paper examines two effective techniques to teach intercultural competence in the classroom setting:critical incident activity and cultural story telling.These two strategies can help achieve the desired objectives of Michael Byram’s intercultural communication model. 展开更多
关键词 intercultural communication intercultural teaching critical incidents cultural story telling
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2020年全国医院感染监控网丙型肝炎病毒感染监测报告 被引量:3
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作者 文细毛 任南 +12 位作者 李福琴 战榕 方旭 孟庆兰 杨怀 李卫光 刘丁 郭凤玲 鲜于舒铭 赖晓全 逄崇杰 黄勋 吴安华 《中国感染控制杂志》 CAS CSCD 北大核心 2024年第1期1-8,共8页
目的了解医疗机构住院患者丙型肝炎病毒(HCV)感染情况及变化趋势,为制定HCV感染防控策略提供参考依据。方法对2020年上报至全国医院感染监控网医院感染横断面调查资料中HCV感染监测结果进行汇总分析,HCV阳性为血清抗-HCV阳性或HCV RNA阳... 目的了解医疗机构住院患者丙型肝炎病毒(HCV)感染情况及变化趋势,为制定HCV感染防控策略提供参考依据。方法对2020年上报至全国医院感染监控网医院感染横断面调查资料中HCV感染监测结果进行汇总分析,HCV阳性为血清抗-HCV阳性或HCV RNA阳性,并与2003年调查结果进行比较。结果2020年1573所医院调查住院患者1071368例,其中738535例患者进行了HCV相关检测,4014例存在HCV感染,检测率为68.93%,HCV阳性率为0.54%。男性患者HCV阳性率为0.60%,女性患者为0.48%,两者比较差异有统计学意义(χ^(2)=47.18,P<0.001)。年龄段以50~<60岁组HCV阳性率最高(0.76%),其次为40~<50岁组,HCV阳性率为0.71%,各年龄段比较差异有统计学意义(χ^(2)=696.74,P<0.001)。2003年调查住院患者91113例,35145例进行HCV相关检测,检测率为38.57%,775例存在HCV感染,HCV阳性率为2.21%。2020年不同规模医院HCV阳性率为0.46%~0.63%,以医院床位数600~899张者最高,不同规模医院患者HCV阳性率比较,差异有统计学意义(χ^(2)=35.34,P<0.001)。2020年有12个省/直辖市/自治区HCV相关检测患者人数>10000例,HCV阳性率为0.19%~0.81%,以海南省最高;不同科室HCV阳性率为0.06%~0.82%,以儿科HCV阳性率最低,内科HCV阳性率最高。2003、2020年HCV阳性率均以感染病科最高,分别为7.95%、3.48%,2003年其次为整形科(7.72%)、消化科(3.77%)、肾病科(3.57%)、综合重症监护病房(ICU,3.10%),2020年其次为消化科(1.35%)、肾病科(1.18%)、内分泌科(0.91%)、综合ICU(0.79%)。结论与2003年相比,2020年HCV阳性率明显下降。HCV感染患者主要分布在感染病科,其次为消化科、肾病科及综合ICU,HCV感染阳性率存在性别、年龄、地域的差异。 展开更多
关键词 肝炎病毒 丙型 丙型肝炎病毒 流行病学调查 住院患者 发病率
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2021年重庆市宫颈癌发病率、死亡率与生存率分析 被引量:1
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作者 丁贤彬 吕晓燕 +3 位作者 焦艳 高旸 熊娟 许杰 《现代肿瘤医学》 CAS 2024年第4期726-731,共6页
目的:了解2021年重庆市宫颈癌发病率、死亡率与五年生存率,为开展恶性肿瘤防治提供依据。方法:收集整理2021年重庆市新发宫颈癌发病死亡数据,分析2021年重庆市宫颈癌发病率、标化发病率、死亡率、标化死亡率、年龄别发病率与死亡率。中... 目的:了解2021年重庆市宫颈癌发病率、死亡率与五年生存率,为开展恶性肿瘤防治提供依据。方法:收集整理2021年重庆市新发宫颈癌发病死亡数据,分析2021年重庆市宫颈癌发病率、标化发病率、死亡率、标化死亡率、年龄别发病率与死亡率。中国人口标化率采用2000年第五次人口普查标准人口构成进行标化,世界人口标化率采用2000年世界人口构成进行标化。不同性别和地区率的比较采用χ^(2)检验。对2016年新报告的宫颈癌病例进行主动和被动生存随访,采用生存分析寿命表法计算观察生存率,采用乘积极限法(Kaplan-Meier)计算平均生存时间,生存率的比较采用Log Rank of Mantel-Cox进行统计检验。结果:2021年重庆市宫颈癌发病率、中国标化发病率、世界标化发病率分别为21.60/10万、14.64/10万与14.71/10万,宫颈癌发病率农村(23.32/10万)高于城市(17.67/10万)(χ^(2)=6.96,P<0.01)。宫颈癌死亡率、中国标化死亡率、世界标化死亡率分别为5.00/10万、2.79/10万与3.02/10万,宫颈癌死亡率农村(5.65/10万)高于城市(3.53/10万)(χ^(2)=5.42,P=0.02)。2021年重庆市宫颈癌五年生存率为64.32%,城市地区宫颈癌五年生存率(76.35%)高于农村地区(59.79%),差异有统计学意义(χ^(2)=46.65,P<0.01)。结论:重庆市宫颈癌发病率与死亡率高,五年生存率较低,应重视宫颈癌的防治。 展开更多
关键词 宫颈癌 发病率 死亡率 生存率
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证券虚假陈述的危险信号理论 被引量:1
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作者 邢会强 《证券市场导报》 CSSCI 北大核心 2024年第1期16-25,50,共11页
在我国证券法上,危险信号开始被用来论证证券虚假陈述的有关责任人未勤勉尽责。危险信号理论的引入,有助于优化签字即担责的执法逻辑,科学精准地打击违法者,但我国对该理论的运用尚处于起步阶段。美国证券法上运用危险信号理论的司法实... 在我国证券法上,危险信号开始被用来论证证券虚假陈述的有关责任人未勤勉尽责。危险信号理论的引入,有助于优化签字即担责的执法逻辑,科学精准地打击违法者,但我国对该理论的运用尚处于起步阶段。美国证券法上运用危险信号理论的司法实践有助于我们更好地判断危险信号,提升危险信号理论的确定性和可预期性。危险信号虽因场景而异,甚至因人而异,但也有一定的边界,其应是发行人自身发生的一项具体事实,需具有警示性,需与被告的主观过错直接相关,并需达到一定的金额或比例。危险信号也是一把双刃剑,既可以用来论证被告未勤勉尽责,也可能因其已被发行人主动披露而导致不够审慎的投资者败诉。 展开更多
关键词 危险信号 信息披露 虚假陈述 勤勉义务 过错推定
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Supervision of Public Opinion under the Background of Social Co-governance-Take the Changsheng Vaccine Incident as an Example
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作者 Ma Xiaonan Tian Lijuan 《Asian Journal of Social Pharmacy》 2023年第3期198-205,共8页
Objective To provide reference for the news media to give play to the role of public opinion supervision in time based on the background of drug safety and social co-governance.Methods The method of case analysis was ... Objective To provide reference for the news media to give play to the role of public opinion supervision in time based on the background of drug safety and social co-governance.Methods The method of case analysis was used to make a retrospective study on the Changsheng vaccine incident in 2018.Then the role of mainstream media,pharmaceutical media,and self-media in the supervision of public opinion was investigated.Results and Conclusion Both mainstream and pharmaceutical media played an excellent role in supervising the Changchun Changsheng vaccine incident.However,the content published by some pharmaceutical media was hard to understand by ordinary people.Besides,the role of self-media in public opinion supervision was polarized.Some self-media closely kept pace with mainstream media in public opinion supervision.Other self-media unilaterally pursued the click rate,publishing false information to guide wrong public opinion.The news media should optimize the supervision efficiency of drug safety.On the one hand,pharmaceutical media should pay attention to the fact that readers may not understand the difficult terms because they are not professional.On the other hand,self-media practitioners should improve their professional quality so that they will not publish some fake news to mislead public opinion. 展开更多
关键词 social co-governance Changchun Changsheng vaccine incident news media public opinion supervision
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