We present the first simulation results of a multi-shell target ignition driven by Z-pinch dynamic hohlraum radiation pulse.The radiation pulse is produced with a special Z-pinch dynamic hohlraum configuration,where t...We present the first simulation results of a multi-shell target ignition driven by Z-pinch dynamic hohlraum radiation pulse.The radiation pulse is produced with a special Z-pinch dynamic hohlraum configuration,where the hohlraum is composed of a single metal liner,a low-Z plastic foam,and a high-Z metallic foam.The implosion dynamics of a hohlraum and a multi-shell target are investigated separately by the one-dimensional code MULTI-IFE.When the peak drive current is 50 MA,simulations suggest that an x-ray pulse with nearly constant radiation temperature(-310 eV)and a duration about 9 ns can be obtained.A small multi-shell target with a radius of 1.35 mm driven by this radiation pulse is able to achieve volumetric ignition with an energy gain(G)about 6.19,where G is the ratio of the yield to the absorbed radiation.Through this research,we better understand the effects of non-uniformities and hydrodynamics instabilities in Z-pinch dynamic hohlraum.展开更多
An experiment was performed on the Shenguang III prototype laser facility to continue the study on hohlraum radiation source with approximately constant radiation temperature using a continuously shaped laser pulse.A ...An experiment was performed on the Shenguang III prototype laser facility to continue the study on hohlraum radiation source with approximately constant radiation temperature using a continuously shaped laser pulse.A radiation source with a flattop temperature of about130 e V that lasted about 5 ns was obtained.The previous analytical iteration method based on power balance and self-similar solution of ablation was modified taking into account the plasma movements and it was used to design the laser pulse shape for experiment.A comparison between experimental results and simulation is presented and better agreement was achieved using the modified method.Further improvements are discussed.展开更多
Objective:Acoustic radiation force impulse(ARFI)was applied to measure Shear wave velocity(SWV)of liver in patients with Wilson's disease(WD).To investigate the relationship between SWV and the serological indexes...Objective:Acoustic radiation force impulse(ARFI)was applied to measure Shear wave velocity(SWV)of liver in patients with Wilson's disease(WD).To investigate the relationship between SWV and the serological indexes of liver fibrosis,such as type Ⅳ collagen(CⅣ),hyaluronic acid(HA),type Ⅲ procollagen peptide(PⅢNP),laminin(LN),APRI score(Asparate Aminotransfer to Platelet Ratio Index),and FIB-4 index(FIB-4 index).The clinical efficacy of GandouTang(GDT)in the treatment of liver fibrosis in WD with damp-heat internalization was also observed.Methods:80 cases of WD patients who met the inclusion criteria were randomly divided into the treatment group and the control group,with 40 cases in each group.The control group was treated with Sodium Dimercaptopropylsulfonate(DMPS)and the treatment group was additionally treated with the traditional Chinese medicine GDT.One course for 8 days,a total of 6 courses.The levels of SwV and four serological indicators of liver fibrosis(PⅢNP,HA,CⅣ,LN),APRI score and FIB-4 index were compared before and after treatment.Pearson correlation test was used to analyze the correlation between SWV and HA,CⅣ,LN,PⅢNP,APRI score and FIB-4 index.The effects of GDT on SWV,liver fiber,APRI and FIB-4 were evaluated according to the treatment plan.Results:①The SWV was positively correlated with FIB-4(r=0.83),APRI(r=0.82),HA(r=0.87),CⅣ(r=0.71),LN(r=0.85)and PINP(r=0.77).②Before treatment,there were no significant differences in SWV level,PⅢNP,HA,CⅣ,LN,APRI and FIB-4 levels between two groups(P>0.05).After treatment,the levels of PⅢNP,HA,LN,SWV,APRI and FIB-4 in both groups were significantly decreased(P<0.05,P<0.01),and the levels in the treatment group were lower than those in the control group.There were no significant specific changes in CⅣ level(P>0.05).Conclusion:SWV value can reflect the degree of WD liver fibrosis,and is positively correlated with HA,PⅢNP,CⅣ,LN,FIB-4 index and APRI score.On the basis of the treatment of protecting liver and expelling copper with western medicine,plus the treatment of traditional Chinese medicine GDT can effectively improve the degree of liver fibrosis in WD patients with damp-heat accumulation.展开更多
The current-mode-counting method is a new approach to observing transient processes,especially in transient nuclear fusion,based on the non-homogeneous Poisson process(NHPP)model.In this paper,a new measurement proces...The current-mode-counting method is a new approach to observing transient processes,especially in transient nuclear fusion,based on the non-homogeneous Poisson process(NHPP)model.In this paper,a new measurement process model of the pulsed radiation field produced by transient nuclear fusion is built based on the NHPP.A simulated measurement is performed using the model,and the current signal from the detector is obtained by simulation based on Poisson process thinning.The neutron time spectrum is reconstructed and is in good agreement with the theoretical value,with its maximum error of a characteristic parameter less than 2.3%.Verification experiments were carried out on a CPNG-6 device at the China Institute of Atomic Energy,with a detection system with a nanosecond response time.The experimental charge amplitude spectra are in good agreement with those obtained by the traditional counting mode,and the characteristic parameters of the time spectrum are in good agreement with the theoretical values.This shows that the current-mode-counting method is effective for the observation of transient nuclear fusion processes.展开更多
基金Project supported by the Science Challenge Project (Grant No. TZ2018001)the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant Nos. XDA25051200 and XDA25050200)+4 种基金the National Natural Science Foundation of China (Grant Nos. 11705282 and 11775305)Hunan Graduate Scientific Research Innovation Project (Grant No. CX20190001)supported by the spanish “Ministerio de Ciencia Innovación y Universidades”project RTI2018-098801-B-100the Spanish “Ministerio de Economía y Competitividad” Project ENE2014-54960-Rthe EURO fusion Consortium project AWP15-ENR-01/CEA-02
文摘We present the first simulation results of a multi-shell target ignition driven by Z-pinch dynamic hohlraum radiation pulse.The radiation pulse is produced with a special Z-pinch dynamic hohlraum configuration,where the hohlraum is composed of a single metal liner,a low-Z plastic foam,and a high-Z metallic foam.The implosion dynamics of a hohlraum and a multi-shell target are investigated separately by the one-dimensional code MULTI-IFE.When the peak drive current is 50 MA,simulations suggest that an x-ray pulse with nearly constant radiation temperature(-310 eV)and a duration about 9 ns can be obtained.A small multi-shell target with a radius of 1.35 mm driven by this radiation pulse is able to achieve volumetric ignition with an energy gain(G)about 6.19,where G is the ratio of the yield to the absorbed radiation.Through this research,we better understand the effects of non-uniformities and hydrodynamics instabilities in Z-pinch dynamic hohlraum.
文摘An experiment was performed on the Shenguang III prototype laser facility to continue the study on hohlraum radiation source with approximately constant radiation temperature using a continuously shaped laser pulse.A radiation source with a flattop temperature of about130 e V that lasted about 5 ns was obtained.The previous analytical iteration method based on power balance and self-similar solution of ablation was modified taking into account the plasma movements and it was used to design the laser pulse shape for experiment.A comparison between experimental results and simulation is presented and better agreement was achieved using the modified method.Further improvements are discussed.
基金Training Program for Young Qhuang Scholars[Chinese Medicine Education Letter(2022)No.256]Key Research and Development Program of Anhui Province(No.202204295107020001)+1 种基金Anhui Young Leaders Reserve Talent Project[No.4,Middle Development(2022)]National Natural Science Foundation of China(No.81973825,82104783)。
文摘Objective:Acoustic radiation force impulse(ARFI)was applied to measure Shear wave velocity(SWV)of liver in patients with Wilson's disease(WD).To investigate the relationship between SWV and the serological indexes of liver fibrosis,such as type Ⅳ collagen(CⅣ),hyaluronic acid(HA),type Ⅲ procollagen peptide(PⅢNP),laminin(LN),APRI score(Asparate Aminotransfer to Platelet Ratio Index),and FIB-4 index(FIB-4 index).The clinical efficacy of GandouTang(GDT)in the treatment of liver fibrosis in WD with damp-heat internalization was also observed.Methods:80 cases of WD patients who met the inclusion criteria were randomly divided into the treatment group and the control group,with 40 cases in each group.The control group was treated with Sodium Dimercaptopropylsulfonate(DMPS)and the treatment group was additionally treated with the traditional Chinese medicine GDT.One course for 8 days,a total of 6 courses.The levels of SwV and four serological indicators of liver fibrosis(PⅢNP,HA,CⅣ,LN),APRI score and FIB-4 index were compared before and after treatment.Pearson correlation test was used to analyze the correlation between SWV and HA,CⅣ,LN,PⅢNP,APRI score and FIB-4 index.The effects of GDT on SWV,liver fiber,APRI and FIB-4 were evaluated according to the treatment plan.Results:①The SWV was positively correlated with FIB-4(r=0.83),APRI(r=0.82),HA(r=0.87),CⅣ(r=0.71),LN(r=0.85)and PINP(r=0.77).②Before treatment,there were no significant differences in SWV level,PⅢNP,HA,CⅣ,LN,APRI and FIB-4 levels between two groups(P>0.05).After treatment,the levels of PⅢNP,HA,LN,SWV,APRI and FIB-4 in both groups were significantly decreased(P<0.05,P<0.01),and the levels in the treatment group were lower than those in the control group.There were no significant specific changes in CⅣ level(P>0.05).Conclusion:SWV value can reflect the degree of WD liver fibrosis,and is positively correlated with HA,PⅢNP,CⅣ,LN,FIB-4 index and APRI score.On the basis of the treatment of protecting liver and expelling copper with western medicine,plus the treatment of traditional Chinese medicine GDT can effectively improve the degree of liver fibrosis in WD patients with damp-heat accumulation.
基金National Natural Science Foundation of China(1435010,11575145,11922507)。
文摘The current-mode-counting method is a new approach to observing transient processes,especially in transient nuclear fusion,based on the non-homogeneous Poisson process(NHPP)model.In this paper,a new measurement process model of the pulsed radiation field produced by transient nuclear fusion is built based on the NHPP.A simulated measurement is performed using the model,and the current signal from the detector is obtained by simulation based on Poisson process thinning.The neutron time spectrum is reconstructed and is in good agreement with the theoretical value,with its maximum error of a characteristic parameter less than 2.3%.Verification experiments were carried out on a CPNG-6 device at the China Institute of Atomic Energy,with a detection system with a nanosecond response time.The experimental charge amplitude spectra are in good agreement with those obtained by the traditional counting mode,and the characteristic parameters of the time spectrum are in good agreement with the theoretical values.This shows that the current-mode-counting method is effective for the observation of transient nuclear fusion processes.