Effectiveness of Histopathological Examination of Ultrasound-guided Puncture Biopsy Samples for Diagnosis of Extrapulmonary Tuberculosis

Objective To evaluate the diagnostic value of histopathological examination of ultrasound-guided puncture biopsy samples in extrapulmonary tuberculosis(EPTB).Methods This study was conducted at the Shanghai Public Health Clinical Center.A total of 115patients underwent ultrasound-guided puncture biopsy,followed by MGIT 960 culture(culture),smear,Gene Xpert MTB/RIF(Xpert),and histopathological examination.These assays were performed to evaluate their effectiveness in diagnosing EPTB in comparison to two different diagnostic criteria:liquid culture and composite reference standard(CRS).Results When CRS was used as the reference standard,the sensitivity and specificity of culture,smear,Xpert,and histopathological examination were(44.83%,89.29%),(51.72%,89.29%),(70.11%,96.43%),and(85.06%,82.14%),respectively.Based on liquid culture tests,the sensitivity and specificity of smear,Xpert,and pathological examination were(66.67%,72.60%),(83.33%,63.01%),and(92.86%,45.21%),respectively.Histopathological examination showed the highest sensitivity but lowest specificity.Further,we found that the combination of Xpert and histopathological examination showed a sensitivity of 90.80%and a specificity of 89.29%.Conclusion Ultrasound-guided puncture sampling is safe and effective for the diagnosis of EPTB.Compared with culture,smear,and Xpert,histopathological examination showed higher sensitivity but lower specificity.The combination of histopathology with Xpert showed the best performance characteristics.

Linear endoscopic ultrasound:Current uses and future perspectives in mediastinal examination

This editorial elaborates on the current and future applications of linear endoscopic ultrasound(EUS),a substantial diagnostic and therapeutic modality for various anatomical regions.The scope of endosonographic assessment is broad and,among other factors,allows for the evaluation of the mediastinal anatomy and related pathologies,such as mediastinal lymphadenopathy and the staging of central malignant lung lesions.Moreover,EUS assessment has proven more accurate in detecting small lesions missed by standard imaging examinations,such as computed tomography or magnetic resonance imaging.We focus on its current uses in the mediastinum,including lung and esophageal cancer staging,as well as evaluating mediastinal lymphadenopathy and submucosal lesions.The editorial also explores future perspectives of EUS in mediastinal examination,including ultrasound-guided therapies,artificial intelligence integration,advancements in mediastinal modalities,and improved diagnostic approaches for various mediastinal lesions.

An Empirical Study of the Socratic Method in Nongraded English Teaching in Senior High School Under the Background of the New National College Entrance Examination

With the reform of the New National College Entrance Examination(Gaokao),the nongraded education will become an inevitable trend.In senior high school,the traditional test-oriented education is popular.The knowledge is mainly taught by the teachers,and the students passively absorb it.This study examines a problem-oriented Socratic experiment in nongraded English teaching in senior high school.The teachers seek output from students,who respond by interpreting questions,fostering critical thinking,and enhancing problem-solving skills.This teaching experiment indicates that the Socratic method has a significant positive effect on cultivating nongraded senior high English students’critical thinking under the New National College Entrance Examination.

Research on the Evaluation of the Implementation Effect of Curriculum Examination Reform: Taking the Course of “Introduction to Language” as an Example

“Introduction to Language,”as the core course of the English major,mainly reveals the basic laws of language,enabling the students to have the ability to apply linguistic theories to explain language phenomena and solve specific language problems.This course is highly theoretical and has a certain degree of difficulty.The evaluation of student grades has always been based on examination reform,but several problems have been encountered during the implementation process.This article analyzes the current situation of the reform and implementation of the“Introduction to Language”course examination in applied universities and puts forth suggestions and specific measures to improve the assessment of the course,aiming to enhance the teaching effectiveness of the course and scientifically and comprehensively evaluate students’abilities.

Improved Mechanism for Detecting Examinations Impersonations in Public Higher Learning Institutions: Case of the Mwalimu Nyerere Memorial Academy (MNMA)

Currently, most public higher learning institutions in Tanzania rely on traditional in-class examinations, requiring students to register and present identification documents for examinations eligibility verification. This system, however, is prone to impersonations due to security vulnerabilities in current students’ verification system. These vulnerabilities include weak authentication, lack of encryption, and inadequate anti-counterfeiting measures. Additionally, advanced printing technologies and online marketplaces which claim to produce convincing fake identification documents make it easy to create convincing fake identity documents. The Improved Mechanism for Detecting Impersonations (IMDIs) system detects impersonations in in-class exams by integrating QR codes and dynamic question generation based on student profiles. It consists of a mobile verification app, built with Flutter and communicating via RESTful APIs, and a web system, developed with Laravel using HTML, CSS, and JavaScript. The two components communicate through APIs, with MySQL managing the database. The mobile app and web server interact to ensure efficient verification and security during examinations. The implemented IMDIs system was validated by a mobile application which is integrated with a QR codes scanner for capturing codes embedded in student Identity Cards and linking them to a dynamic question generation model. The QG model uses natural language processing (NLP) algorithm and Question Generation (QG) techniques to create dynamic profile questions. Results show that the IMDIs system could generate four challenging profile-based questions within two seconds, allowing the verification of 200 students in 33 minutes by one operator. The IMDIs system also tracks exam-eligible students, aiding in exam attendance and integrates with a Short Message Service (SMS) to report impersonation incidents to a dedicated security officer in real-time. The IMDIs system was tested and found to be 98% secure, 100% convenient, with a 0% false rejection rate and a 2% false acceptance rate, demonstrating its security, reliability, and high performance.

Profile of Radiological Examinations in the Radiology and Medical Imaging Department of the Medical Clinic “KALALE” in Mali

Introduction: Radiology and medical imaging examinations bring together the means of acquiring and restoring images of the human body from different physical phenomena such as the absorption of X-rays, nuclear magnetic resonance, reflection of ultrasound waves or radioactivity, with which we sometimes associate optical imaging techniques such as endoscopy. The objective of our study was to study the profile of radiological examinations in the radiology and medical imaging department of the “KALALE” medical clinic. Methodology: This was a descriptive, prospective study that took place over a period of six (6) months in the radiology and medical imaging department of the “KALALE” medical clinic and the centers of health of communes III and IV of Bamako in Mali. Data collection was carried out on a survey form. The parameters studied were sociodemographic data, clinical data, radiological data. Results: We recorded 6030 radiology examinations of which 19% of the examination frequency cases came from the “KALALE” medical clinic and 81% of the cases were referrals from the reference health centers of communes III and IV. There were 1500 X-rays or 24.9% of cases including 54% cases of bone X-rays;5% of cases of skull and face X-rays;5% of cases of Intravenous Urography (IVU);4% of cases of Hysterosalpingography (HSG);3% of cases of Retrograde Ureterocystography (UCR) and 1% of cases of X-ray of the Abdomen without preparation (ASP). We found 4530 ultrasounds or 75.1% of cases. Conclusion: Medical imaging has become essential in the study of the human body and now constitutes an essential tool for the detection and treatment of most pathologies, from simple fractures to the most serious tumors.

A Physical Examination Method for Artificial Rainfall Effect Based on Radar Data

[Objective] This study aimed to establish a physical examination method for artificial rainfall effect based on radar data. [Method] The radar base data of Shenyang was processed with interpolation by using the nearest neighbor in radial and oriental direction to establish corresponding response variables, and the effect of a precipitation enhancement case was analyzed. [Result] The trends of response variables showed that there was certain positive effect of the precipitation enhancement operation. [Conclusion] The analysis on a case was not sufficient enough, and statistical test should be the future direction of the study on the physical effect.

谈谈与examination搭配的词语

本文结合相关辞书,概述与examination相关的表达。1.用prepare/revise/studyfor等表示“为考试而准备”“复习迎考”“温习备考”。例如:We are preparing for the examination next week.我们正在为下周的考试做准备。I do not have much time to revise for examinations.我没有很多时间复习迎考。Ineed time to study for tomorrow's exami nation.我需要时间学习,准备明天的考试。

EXAMINATION OF SPUTUM SEDIMENT PARAFFIN SECTION OF DIAGNOSIS OF LUNG CANCER

To establish the rapid and accurate methods for detecting cancer cells from the sputum of patients with lung cancer. Methods: Sputum sediment section examination and sputum smear examination were performed. For 142 cases of lung cancer patients diagnosed by bronchia fibrous lens and confirmed by pathologic diagnosis. Results: (a) The positive diagnosis rate of lung cancer cell was 71.83% (102/142) when using sputum sediment examination while that was 32.39% (46/142) when using sputum smear examination, when using sputum sediment examination jointly with sputum smear examination, the positive diagnosis rate of lung cancer was 91.55% (130/142). According to the positive diagnosis rate of lung cancer, the sputum sediment examination was significantly higher than sputum smear examination (P<0.001), joint examination of both of them was significantly higher than the single sputum sediment examination (P<0.001); (b) As to the histopathological types of lung cancers, 66 cases could be identified among 102 cases whom were confirmed by sputum sediment examination, the identification rate was 64.71%; and 8 cases could be identified among 46 cases whom were confirmed by sputum smear examination, with an identification rate of 17.39%, it was significantly lower than that by sputum sediment examination (P<0.001); (c) Immunohistochemistry technique could be used in the sections of sputum sediment to identify some histopathological types which could not be identified by routine HE stain, with an identification rate of 94.44% (34/36). Conclusion: the sputum sediment examination has some advantages compared to the sputum smear examination such as the specimen may include more materials, the higher cancer cell identification positive rate and immunohistochemistry method can be used to identify the histopathological type.

Musculoskeletal Examination Skills: Are We Still Interested?

This article explores problems and solutions of Musculoskeletal (MSK) examinations skills and points out that it is very important to keep medical educators interested to improve the situation of MSK teaching. MSK conditions are usually overlooked though they represent 20% of both primary care and emergency-room visits of the most common health complications that require medical attention across the world. MSK disorders can lead to serious disabilities and significant burden and though its problems are expected to increase, there is a continuous neglect in musculoskeletal examination skills in clinical practice. To participate in solving this problem, the article accentuates the necessity of defining MSK competencies and of agreeing on standards of MSK exams and calls for an integrated teaching of MSK examination skills that uses interactive methodologies like patients’ educators and peer-assisted learning. This article comprises four parts, an introduction, a description of the deficiencies in musculoskeletal examination skills, the causes of these deficiencies and finally some solutions of musculoskeletal examination skills deficiencies. We venture to bring attention to an overlooked but major analyses constituent that impacts patients’ overall health.

Orientation and Function of Examination Evaluation in the Reform of College Entrance Examination

With the aim of deepening the college entrance examination reform,this paper analyzes the orientation and role of examination evaluation in the reform of college entrance examination.Firstly,the paper expounds the implementation of the college entrance examination reform and affirms the necessity of several related educational reforms.Secondly,it expoxmds the orientation of examination evaluation.Finally,it summarizes the function of examination evaluation from four aspects:guiding the development of students*comprehensive quality,supervising teaching work,promoting the progress of teaching work,and guiding examination propositions.The advantages of examination evaluation are emphasized to promote the reform of college entrance examination and further drive the progress of the education reform in China.

A nomogram based on age, prostate-specific antigen level, prostate volume and digital rectal examination for predicting risk of prostate cancer

Nomograms for predicting the risk of prostate cancer developed using other populations may introduce sizable bias when applied to a Chinese cohort. In the present study, we sought to develop a nomogram for predicting the probability of a positive initial prostate biopsy in a Chinese population. A total of 535 Chinese men who underwent a prostatic biopsy for the detection of prostate cancer in the past decade with complete biopsy data were included. Stepwise logistic regression was used to determine the independent predictors of a positive initial biopsy. Age, prostate-specific antigen （PSA）, prostate volume （PV）, digital rectal examination （DRE） status, % free PSA and transrectal ultrasound （TRUS） findings were included in the analysis. A nomogram model was developed that was based on these independent predictors to calculate the probability of a positive initial prostate biopsy. A receiver-operating characteristic curve was used to assess the accuracy of using the nomogram and PSA levels alone for predicting positive prostate biopsy. The rate for positive initial prostate biopsy was 41.7% （223/535）. The independent variables used to predict a positive initial prostate biopsy were age, PSA, PV and DRE status. The areas under the receiver-operating characteristic curve for a positive initial prostate biopsy for PSA alone and the nomogram were 79.7% and 84.8%, respectively. Our results indicate that the risk of a positive initial prostate biopsy can be predicted to a satisfactory level in a Chinese population using our nomogram. The nomogram can be used to identify and counsel patients who should consider a prostate biopsy, ultimately enhancing accuracy in diagnosing prostate cancer.

Chinese expert consensus on the non-invasive imaging examination pathways of stable coronary artery disease

1 Introduction Early detection and diagnosis of stable coronary artery disease （SCAD） is essential for proactive secondary prevention of myocardial infarction （MI）, control of disease progress, and reduction of mortality. Clinical decision-making in modem medicine is increasingly dependent on cardiovascular imaging techniques. 2012 ACCF/AHA/ACP/AATS/ PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease has been issued by American Heart Association （AHA）. European Society of Cardiology （ESC） has issued 2013 ESC guidelines on the management of stable coronary artery disease.

Low skeletal muscle mass is associated with non-alcoholic fatty liver disease in Korean adults： the Fifth Korea National Health and Nutrition Examination Survey

BACKGROUND： Sarcopenia and non-alcoholic fatty liver dis- ease （NAFLD） share similar pathophysiological mechanisms, and the relationship between sarcopenia and NAFLD has been recently investigated. The study investigated whether low skel- etal muscle mass is differentially associated with NAFLD by gender in Korean adults. METHODS： We conducted a cross-sectional analysis of the data from the Fifth Korea National Health and Nutrition Examination Survey. The skeletal muscle index （SMI） was obtained by the appendicular skeletal muscle mass divided by the weight. NAFLD was defined as a fatty liver index （FLI） 〉60 in the absence of other chronic liver disease. RESULTS： Among the included subjects, 18.3% （SE： 1.4%） in men and 7.0% （SE： 0.7%） in women were classified as having FLI-defined NAFLD. Most of the risk factors for FLI-defined NAFLD showed a significant negative correlation with the SMI in both genders. Multiple logistic regression analysis showed that low SMI was associated with FLI-defined NAFLD, inde- pendent of other metabolic and lifestyle parameters in both genders [males： odds ratio （OR）=1.35; 95% confidence inter- val （CI）： 1.17-1.54; females： OR=1.36; 95% CI： 1.18-1.55]. The magnitude of the association between FLI-defined NAFLD and low SMI was higher in middle aged to elderly males （OR-1.50; 95% CI： 1.22-1.84） than in males less than 45 years of age （OR=1.25; 95% CI： 1.02-1.52） and in premenopausal females （OR=l.50; 95% CI： 1.12-2.03） than in postmenopausal females （OR-1.36; 95% CI： 1.20-1.54）.CONCLUSIONS： Low SMI is associated with the risk of FLI- defined NAFLD independent of other well-known metabolic risk factors in both genders. This association may differ ac- cording to age group or menopausal status. Further studies are warranted to confirm this relationship.

Breeding Soundness Examination of Breeding Bull after Infecting Mycoplasma wenyonii

[Objective] The research aimed to study the reproductive health of breed- ing bull after infecting Mycoplasma wenyoniL [Method] The blood and semen quality of breeding bull before and after drug treatment was studied by the methods of blood routine examination and breeding soundness examination （BSE）. [Result] Be- fore the treatment with primaquine phosphate, slight anaemia was seen in diseased bull and a lot of M.wenyonfi were seen on blood smears. The scrotal wall of dis- eased bull swelled, testis was softened, the semen quality was reduced, semen quality was decreased and the proportion of primary and secondary deformed sperms was increased. After drug treatment, M.wenyonfi quickly disappeared from blood and the clinical systems were gradually alleviated, so BSE of breeding bulls after one month was passed. [Conclusion] The research laid the foundation for fur- ther study on the relationship between M.wenyonfi and the reduction of bull＇s repro- ductive functions.

Outcomes of 957 preterm neonatal fundus examinations in a Guangzhou NICU through 2008 to 2011

AIM: To take fundus examination in the preterm neonates to observe the common diseases and report the outcomes in a neonatal intensive care unit (NICU) in Guangzhou between May 2008 and May 2011. METHODS: Fundus examinations were performed with Retcam II in 957 prematures. RESULTS: There were 957 prematures in this study, including 666 males and 291 females, 2 triple births, 152 twins and 803 singletons. During the three years, 86 infants with any stage retinopathy of prematurity (ROP) (9.0%), 123 infants with retinal hemorrhage (12.9%), 10 infants with neonatal fundual jaundice (1.0%) and 3 babies with congenital choroidal coloboma (0.3%) were found. CONCLUSION: Early detection and prompt treatment of ocular disorders in neonates is important to avoid lifelong visual impairment. Examination of the eyes should be performed in the newborn period and at all well-child visits.

Comparison of RN licensure examination: China and the United States

Having the two largest nursing workforces across the globe,both China and the United States have implemented licensure examinations to standardize the qualifications of registered nurse.China established the National Nursing Licensure Examination(NNLE)in 1995.Like the National Council Licensure Examination for Registered Nurses(NCLEX-RN)in the United States,the NNLE has become an important link in the nurse registration process and contributed a lot in quality assurance and development of nursing profession.It may be necessary for the NNLE to learn from NCLEX-RN in several aspects,including increasing the frequency of exam,providing examinees with individualized services,and continuing reforming exam content and format.By better aligning the content and format of the examination with the current nursing paradigm and clinical requirements,nurses may enter the healthcare field better prepared to care for patients.Considering the magnitude of their nursing workforce,both China and the United States have great potential to serve as a role model for other developing countries as they look towards establishing national nursing education programs.As new policies around standardized nurse education in China take form,we urge that the NNLE be included alongside curricular reforms.As these reforms are implemented,continued research will be needed to evaluate the effectiveness of curriculum and licensure exam regulations upon nurse preparedness and quality of nursing care in China.

An enrichment model using regular health examination data for early detection of colorectal cancer

Objective: Challenges remain in current practices of colorectal cancer(CRC) screening, such as low compliance,low specificities and expensive cost. This study aimed to identify high-risk groups for CRC from the general population using regular health examination data.Methods: The study population consist of more than 7,000 CRC cases and more than 140,000 controls. Using regular health examination data, a model detecting CRC cases was derived by the classification and regression trees(CART) algorithm. Receiver operating characteristic(ROC) curve was applied to evaluate the performance of models. The robustness and generalization of the CART model were validated by independent datasets. In addition, the effectiveness of CART-based screening was compared with stool-based screening.Results: After data quality control, 4,647 CRC cases and 133,898 controls free of colorectal neoplasms were used for downstream analysis. The final CART model based on four biomarkers(age, albumin, hematocrit and percent lymphocytes) was constructed. In the test set, the area under ROC curve(AUC) of the CART model was 0.88 [95%confidence interval(95% CI), 0.87-0.90] for detecting CRC. At the cutoff yielding 99.0% specificity, this model’s sensitivity was 62.2%(95% CI, 58.1%-66.2%), thereby achieving a 63-fold enrichment of CRC cases. We validated the robustness of the method across subsets of test set with diverse CRC incidences, aging rates, genders ratio, distributions of tumor stages and locations, and data sources. Importantly, CART-based screening had the higher positive predictive value(1.6%) than fecal immunochemical test(0.3%).Conclusions: As an alternative approach for the early detection of CRC, this study provides a low-cost method using regular health examination data to identify high-risk individuals for CRC for further examinations. The approach can promote early detection of CRC especially in developing countries such as China, where annual health examination is popular but regular CRC-specific screening is rare.

A review on rules for examination of licensing criteria for producing foods for special medical purpose in China

In this paper,the background,principles,and main contents of the rules for the examination of production licenses of foods for special medical purposes are introduced.The contents including general rules,production sites,equipment facilities,equipment layout,technological process,personnel management,management system and supplementary rules are interpreted item by item.This study has important value and historical significance for promoting the development of Chinese enterprises and industries of foods for special medical purposes.

City Health Examination in China:A Methodology and Empirical Study

National urban planning,construction,and management levels have undergone qualitative changes in China since 2000.Nonetheless,problems caused by rapid urbanization are becoming increasingly prominent.The concept of the city health examination appears to tackle these problems and is being gradually implemented,starting from the implementation of a national strategy and leading to the concrete practice of high-quality urban development.This paper elaborates on the basic philosophy and theory of the city health examination,briefly explains indicator selection and aims,and comprehensively illustrates examination methods.It then describes the empirical research that operationalized the dataset collected from a satisfaction survey administered during the 2020 city health examination.It aims to provide a reference for the standardization,specialization,analysis,and application of the results of the city health examination in China;this may help promote a smooth elimination of‘urban diseases’and allow for the development of high-quality livable cities.This research shows that city residents are generally more satisfied with the landscape features,ecological livability,and security resilience;it also shows that residents are generally more dissatisfied with traffic issues.Residents with different characteristics showed different satisfaction levels toward different indicators.Residents were also shown to be more sensitive to innovation vitality,ecological livability,and health and comfort in considering whether to stay in their current city.