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Effect of sodium nitroprusside on the microrheological properties of red blood cells in different media 被引量:1
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作者 Petr Ermolinskiy Matvey Maksimov +3 位作者 Andrei Lugovtsov Alexey Muravyov Irina Tikhomirova Alexander Priezzhev 《Journal of Innovative Optical Health Sciences》 SCIE EI CSCD 2024年第5期23-31,共9页
Red blood cell(RBC)aggregation as well as their deformation significantly affects blood microrheology.These processes depend on various factors,one of which is concentration of the nitric oxide,one of the main signali... Red blood cell(RBC)aggregation as well as their deformation significantly affects blood microrheology.These processes depend on various factors,one of which is concentration of the nitric oxide,one of the main signaling molecule in the bloodstream.The purpose of this study was to investigate the effect of nitric oxide on the microrheological properties of red blood cells(RBCs)in RBC samples of various media after the addition of nitric oxide donor sodium nitroprusside in vitro.Microrheological properties were measured using laser aggregometer and ektacytometer based on diffuse light scattering and diffraction of laser light on a suspension of RBCs,respectively.The study found that heparin-stabilized blood showed increased RBC aggregation and deformation with sodium nitroprusside concentrations of 100,and 200M,while EDTA-stabilized blood showed slightly decreased aggregation and unchanged deformation.With washed RBCs in dextran solution,the addition of sodium nitroprusside(in the concentrations of 100,and 200M)resulted in decreased aggregation and increased deformation.These-ndings aid in our understanding of nitric oxide's effect on RBC microrheological properties. 展开更多
关键词 Sodium nitroprusside nitric oxide red blood cells RBC aggregation diffuse light scattering laser diffractometer
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Sodium nitroprusside as a signal molecule for up-regulating membrane characteristics,antioxidant defense system to improve flax productivity under water stress
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作者 N.M.Al-Ashkar B.A.Bakry +2 位作者 H.M.S.El-Bassiouny M.M.S.Abdallah M.S.Sadak 《Oil Crop Science》 CSCD 2024年第3期160-169,共10页
Water stress is a critical environmental adversity that significantly impacts the growth,development,and yield of flax plants.In this study,flax seeds were cultivated under different water irrigation requirements(WIR)... Water stress is a critical environmental adversity that significantly impacts the growth,development,and yield of flax plants.In this study,flax seeds were cultivated under different water irrigation requirements(WIR)(100%,75%,and 50%)to investigate the effects of exogenously supplied nitric oxide(NO)donor sodium nitroprusside(SNP)as foliar treatments at concentrations of 0.0 mmol/L,0.5 mmol/L,1.0 mmol/L,and 2.0 mmol/L.Drought stress led to a significant decrease in plant growth,photosynthetic pigments,yield components such as oil and total carbohydrate percentage.It also resulted in an increase in leaf H2O2 production,lipid peroxidation levels and activities of enzymatic antioxidants including polyphenol oxidase,superoxide dismutase,and nitrate reductase enzymes.However,foliar application of SNP improved photosynthetic pigments and antioxidant defense system which mitigated the negative impact of water stress on growth and yield productivity by reducing oxidative damage caused by reactive oxygen species accumulation.The use of SNP also decreased H_(2)O_(2) accumulation levels,lipid peroxidation levels,and improved membrane stability.SNP treatment at concentration of 2 mmol/L showed superior results compared to other concentrations with extremely significant increases observed in yield characteristics such as oil content,total carbohydrate percentages,and unsaturated fatty acids to saturated fatty acids ratio. 展开更多
关键词 FLAX Fatty acid Sodium nitroprusside Antioxidant enzymes YIELD
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A clinical comparative study on effects of intracavernous injection of sodium nitroprusside and papaverine/phentolamine in erectile dysfunction patients 被引量:3
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作者 QiangFU De-HongYAO Yue-QinJIANG 《Asian Journal of Andrology》 SCIE CAS CSCD 2000年第4期301-303,共3页
Aim: To study the effect of intracavemous sodium nitropmsside (SNP), a nitric oxide (NO) donor, on penile erec-tion. Methods: Forty-two patients with erectile dysfunction (ED) were randomly assigned to receive SNP 300... Aim: To study the effect of intracavemous sodium nitropmsside (SNP), a nitric oxide (NO) donor, on penile erec-tion. Methods: Forty-two patients with erectile dysfunction (ED) were randomly assigned to receive SNP 300μgor the control drags (papaverine 30 mg + phentolamine 1 mg) intracavemously crosswise one week apart. The penilelength, circumference and hardness after the administration of the experimental and control drags were assessed andcompared statistically. Results: (1) There was no significant difference between the changes in penile length andcircumference in the two occasions; (2) In 25 SNP and 28 control cases, the hardness of the penis was scored above100 as evaluated by the Vimg method (P > 0.05); (3) The duration of erection in the controls was longer than that inthe SNP, but there were three priapism in the controls and not a single one in the SNP; (4) there was no apparentchange in the heart rate and blood pressure in both occasions; other side effects were minimal except slight local pain ina few controls. Conclusion: SNP facilitates relaxation of the penile smooth muscle and penile erection without sig-nificant side effects. SNP may be used in ED patients that experience pain and priapism with papaverine/phentolamine.(Asian J Androl 2000 Dec; 2: 301-303) 展开更多
关键词 erectile dysfuntion intracavemous injection sodium nitroprusside nitric oxide
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Sodium nitroprusside injection immediately before balloon inflation during percutaneous coronary intervention 被引量:4
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作者 Yan Yu Bao-Ping Yang 《World Journal of Clinical Cases》 SCIE 2021年第36期11248-11254,共7页
BACKGROUND No reflow or slow flow frequently occurs during percutaneous coronary intervention(PCI)and it is associated with adverse outcomes.Strategies should be undertaken to prevent its occurrence.AIM To observe whe... BACKGROUND No reflow or slow flow frequently occurs during percutaneous coronary intervention(PCI)and it is associated with adverse outcomes.Strategies should be undertaken to prevent its occurrence.AIM To observe whether conventional target intracoronary administration of sodium nitroprusside immediately before balloon inflation can reduce the incidence of no reflow and slow flow,which are defined as thrombolysis in myocardial infarction flow grade≤II during PCI.METHODS A retrospective study was conducted in 740 patients with coronary artery disease admitted to Gansu Provincial Hospital of Traditional Chinese Medicine between January 2016 and October 2020.Among them,360 patients receiving sodium nitroprusside immediately before balloon inflation during PCI were enrolled in an experimental group between January 2019 and October 2020 and 380 patients receiving sodium nitroprusside after incident no reflow and slow flow during PCI were enrolled in a control group between January 2016 and January 2019.The occurrence of no reflow and slow flow was compared between the two groups and left ventricular end-diastolic diameter(LVEDD)and left ventricular ejection fraction(LVEF)were detected 1 mo after the operation.RESULTS After treatment,the proportion of patients with thrombolysis in myocardial infarction flow grades 0 to II was lower in the experimental group than in the control group(P<0.05).At 1 mo after treatment,LVEDD was lower and LVEF was higher in the experimental group than in the control group(P<0.05).In terms of incidence of adverse cardiovascular events within 1 mo after treatment,in the experimental group,malignant arrhythmia occurred in three patients,intractable myocardial ischemia in three,congestive heart failure in four,and recurrent myocardial infarction in five;one patient died.In the control group,malignant arrhythmia occurred in eight patients,intractable myocardial ischemia in five,congestive heart failure in seven,and recurrent myocardial infarction in 14;two patients died.The incidence of adverse cardiovascular events was 4.4%in experimental group which was lower than that of the control group at 1 mo after operation(9.5%;P<0.05).CONCLUSION Administration of sodium nitroprusside into target vessels immediately before balloon inflation can significantly reduce the incidence of no reflow and slow flow,improve LVEDD and LVEF,and reduce the incidence of adverse cardiovascular events in patients treated by PCI.It is worthy of clinical promotion. 展开更多
关键词 Sodium nitroprusside No reflow Slow blood flow Coronary artery disease Percutaneous coronary intervention
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Antioxidant properties of aqueous extracts of unripe Musa Paradisiaca on sodium nitroprusside induced lipid peroxidation in rat pancreas in vitro 被引量:2
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作者 Sidiqat Adamson Shodehinde Ganiyu Oboh 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2013年第6期449-457,共9页
Objective:To evaluate and compare antioxidant activities of the aqueous extracts of unripe plantain(Musa paradisiaca),assess their inhibitory action on sodium nitroprusside induced lipid peroxidation in rat pancreas i... Objective:To evaluate and compare antioxidant activities of the aqueous extracts of unripe plantain(Musa paradisiaca),assess their inhibitory action on sodium nitroprusside induced lipid peroxidation in rat pancreas in vitro and to cliaracterize the main phenolic constituents of the plantain products using gas chromatography analysis.Methods:Aqueous extracts of plantain products(raw,elastic pastry,roasted and boiled)(lour ol 0.1 g/mL(each)were used to determine their total phenol,total flavonoid,1,1 diphenyl-2 picrylhydrazyl(DPPH)and hydroxyl(OH)radical scavenging ability.The inhibitory effect of the extracts on sodium nitropmsside induced lipid peroxidation was also determined.Results:The results revealed that all the aqueous extracts showed antioxidant activity.The boiled Hour had highest DPPH and OH radical scavenging ability while raw Hour had the highest Fe^(2+)chelating ability,sodium nilroprusside inhibitor)effect and vitamin C content.The antioxidant results showed that elastic pastry had the highest total phenol and total flavonoid content.Characterization of the unripe plantain products for polyphenol contents using gas chromatography showed varied quantity of apigenin,myricetin.luteolin,capsaicin,isorhaemnetin.caffeic acid,kampferol,quercetin,p-hydroxybenzoic acid,shogaol,glycitein and gingerol per product on the spectra.Conclusions:Considering the antioxidant activities and ability to inhibit lipid peroxidation of unripe plantain,this could justify their traditional use in the management/prevention of diseases related to stress. 展开更多
关键词 POLYPHENOLS ANTIOXIDANTS MUSA paradisiaca Sodium nitroprusside LIPID PEROXIDATION
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A novel method for the spectrophotometric determination of cefradine by using sodium nitroprusside as chromogenic reagent 被引量:2
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作者 Hua Zhang Ling Li Wu +1 位作者 Quan Min Li Xin Zhen Du 《Chinese Chemical Letters》 SCIE CAS CSCD 2008年第12期1470-1474,共5页
A novel method is developed for the determination of cefradine by using sodium nitroprusside as chromogenic reagent. The experiment indicates that a russety product is formed by the reaction of cefradine with sodium n... A novel method is developed for the determination of cefradine by using sodium nitroprusside as chromogenic reagent. The experiment indicates that a russety product is formed by the reaction of cefradine with sodium nitroprusside in basic solution, and the maximum absorption wavelength (λmax) of russety product is 505 rim. And the sensitization of tetradecyl benzyl dimethyl ammonium chloride for the reaction of cefradine with sodium nitroprusside is remarkable, The apparent molar absorption coefficient (5505) is 2.81 × 103 L/mol cm. The linear equation isA = 0.0657 + 0.00804C (μg/mL) in the range of 1.50-55.0μg/mL of cefradine with a correlation coefficient r = 0.9992, and the detection limit is 1.38 p,g/mL. This method has been applied to determine cefradine in capsule and tablet samples. 展开更多
关键词 CEFRADINE Sodium nitroprusside Chromogenic reagent SPECTROPHOTOMETRY
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Central Nervous System Toxicity of Sodium Nitroprusside in Treatment of Patients with Aortic Dissection 被引量:2
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作者 黄雪渊 侯凌波 +3 位作者 唐家荣 张艳梅 陈复琼 汪道文 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2012年第6期927-930,共4页
This study examined the sodium nitroprusside (SNP) toxicity to central nervous system (CNS) in treatment of patients with aortic dissection (AD). The medical records of 191 AD patients who were admitted to Tongji Hosp... This study examined the sodium nitroprusside (SNP) toxicity to central nervous system (CNS) in treatment of patients with aortic dissection (AD). The medical records of 191 AD patients who were admitted to Tongji Hospital, China, from Jan. 1998 to Feb. 2009 were retrospectively analyzed. There were 140 cases of hypertension (73.3%) and 13 cases of Marfan syndrome (6.8%) among the 191 AD patients. A total of 157 patients were given SNP treatment. The toxic reactions of CNS occurred in 18 subjects (11.5%). Most of the adverse reactions occurred on the fifth day following SNP injection. SNP infusion rate was significantly higher in patients who developed CNS toxicity. It was suggested that systemic hypertension is the most common predisposing factor for AD. The combination of SNP with a β-receptor blocker is a medical therapy commonly used in patients with AD. Cyanide and thio-cyanate toxicity from SNP treatment is always the consequence of prolonged drug infusion or relatively high dose administration. 展开更多
关键词 sodium nitroprusside TOXICITY central nervous system aortic dissection
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Lack of nitrate tolerance in isosorbid dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter
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作者 Ayhan Koyuncu Ihsan Bagcivan +3 位作者 Bulent Sarac Cengiz Aydin Sahin Yildirim Yusuf Sarioglu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2008年第29期4667-4671,共5页
AIM: To investigate the tolerance development against the relaxant effect of nitric oxide donating drug isosorbide dinitrate (ISDN) and sodium nitropruside (SNP) in internal anal sphincter (IAS) smooth muscle. METHODS... AIM: To investigate the tolerance development against the relaxant effect of nitric oxide donating drug isosorbide dinitrate (ISDN) and sodium nitropruside (SNP) in internal anal sphincter (IAS) smooth muscle. METHODS: Relaxation responses of ISDN, and electrical fi eld stimulation (EFS) were obtained before and after tolerance induction by ISDN incubation. RESULTS: ISDN (10-7-10-4 mol/L) and SNP (10-8-10-4 mol/L) caused a concentration-dependent relaxation on the basal tonus of the isolated rabbit IAS strips. After a period of 2 h incubation of the 6 x 10-4 mol/L ISDN the relaxation effects of ISDN and SNP did not change compared to control strips. EFS evoked frequency-dependent relaxation in internal anal sphincter smooth muscle and Emax obtained from control strips were not changed in ISDN tolerance-inducing condition. In this study nitrate tolerance was not observed in rabbit IAS smooth muscle. CONCLUSION: This result shows that nitric oxide donating drugs relaxes the internal anal sphincter of the rabbits without the development of tolerance. 展开更多
关键词 Internal anal sphincter Nitrate tolerance Isosorbide dinitrate Sodium nitroprusside Nitric oxide
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Effect of intracoronary sodium nitroprusside and tirofiban injection on myocardial injury in patients with no reflow in PCI
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作者 Xiang-Yang Xia 《Journal of Hainan Medical University》 2018年第4期18-21,共4页
Objective: To study the effect of intracoronary sodium nitroprusside and tirofiban injection on myocardial injury in patients with no reflow in PCI. Methods: Patients with acute coronary syndrome who underwent PCI and... Objective: To study the effect of intracoronary sodium nitroprusside and tirofiban injection on myocardial injury in patients with no reflow in PCI. Methods: Patients with acute coronary syndrome who underwent PCI and had no reflow in Gong'an County People's Hospital in Hubei Province between August 2014 and July 2017 were selected as the research subjects and randomly divided into two groups, combined group accepted intracoronary sodium nitroprusside and tirofiban injection during PCI, and control group accepted intracoronary tirofiban injection during PCI. The serum levels of myocardial injury indexes, oxidative stress indexes and inflammatory mediators of the two groups were measured before treatment and 1 d after treatment. Results: 1 d after treatment, serum CK-MB, H-FABP, sFas, cMyBP-C, MPO, MDA, Caspase-3, MCP-1, IL-1β, IL-18, MMP2 and MMP9 levels of both groups were significantly lower than those before treatment whereas SOD and NQO-1 levels were higher than those before treatment, and serum CK-MB, H-FABP, sFas, cMyBP-C, MPO, MDA, Caspase-3, MCP-1, IL-1β, IL-18, MMP2 and MMP9 levels of combined group were significantly lower than those of control group whereas SOD and NQO-1 levels were higher than those control group. Conclusion: Intracoronary sodium nitroprusside and tirofiban injection can reduce the myocardial injury in patients with no reflow in PCI. 展开更多
关键词 PERCUTANEOUS coronary intervention Sodium nitroprusside Tirofiban No REFLOW MYOCARDIAL injury
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The Effect of Exogenous Sodium Nitroprusside Treatment on Broccoli Quality During the Storage Process
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作者 WANG Qing SHI Jun-yan +2 位作者 YANG Na GAO Li-pu PANG Jie 《Chinese Food Science》 2012年第3期13-15,19,共4页
[Objective] The aim was to provide certain theoretical basis for the protection of broccoli. [Method] Exogenous sodium nitroprusside was used to in the experiment. Under the condition of 20 ℃ and RH 95%, the optimal ... [Objective] The aim was to provide certain theoretical basis for the protection of broccoli. [Method] Exogenous sodium nitroprusside was used to in the experiment. Under the condition of 20 ℃ and RH 95%, the optimal SNP concentration of broccoli was determined. [Result] The exogenous SNP could effectively maintain the quality of broccoli, inhabited the yellowing of broccoli and the increasing of cell membrane permeability, and maintain the soluble solids content, decreased the degradation rate of chlorophyll and delayed the loss of VC. [Conclusion] Exogenous sodium nitroprusside can effectively maintain the quality of broccoli to keep it fresh. 展开更多
关键词 BROCCOLI Sodium nitroprusside(SNP) STORAGE QUALITY China
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CHARACTERISTICS OF CIRCULATORY MECHANICS AND HEMODYNAMICS EFFECTED BY GASTRODIN AND SODIUM NITROPRUSSIDE
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作者 Wang Zhengrong Luo Honglin +3 位作者 Xiao Jin Guo Huiling Li Hai Xue Zhennan 《Chinese Journal of Biomedical Engineering(English Edition)》 1994年第2期47-57,共11页
The purpose of this study is to investigate effects of gastrodin and sodium nitroprusside on circulatory mechanics and hemodynamics.The modified Windkessel model was used to calculate arterial vascular compliance and ... The purpose of this study is to investigate effects of gastrodin and sodium nitroprusside on circulatory mechanics and hemodynamics.The modified Windkessel model was used to calculate arterial vascular compliance and inertance of blood flow in the arterial vessels.Blood pressure,cardiac output,peripheral resistance,inertance of blood flow in the arterial vessels,and proximal and distal compliance etc in 20 dogs were measured and calculated before and after gastrodin and sodium nitroprusside ad-ministration.The results show that gastrodin is efficient in decreasing the blood pres-sure(P<0.001)and peripheral resistance(P<0.01),and increasing the proximal(P<0.05)and distal arterial vascular compliance(P<0.01),and inertance of blood flow in the arterial vessels(P=0.054).Sodium nitroprusside strongly de·eases bloood pres-sure and peripheral resistance(P<0.001),and increases distal arterial compliance(P<0.001)and inertance of blood flow in the arterial vessels(P<0.01).Comparing with sodium nitropursside,gastrodin is moderate in reducing blood pressure,but it reduces systolic blood pressure is relatively stronger than it does diastolic blood pressure.Fur-thermore,gastrodin is stronger than sodium nitroprusside and some of other vasodila-tors in increasing proximal arterial compliance,i.e.,gastrodin has the beneficial ef-fect of improving arterial vascular,particularly aorta and large artery,elasticity.Gas-trodin,as a traditional Chinese medicine,can be used to cure the elderly hypertension. 展开更多
关键词 GASTRODIN Sodium nitroprusside Circulatory mechanics Modified Windkessel model HEMODYNAMIC
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The Releasing Effects of Captopril and Sodiun Nitroprusside on Endothelin-1 in Vascular Smooth Muscle Cell
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作者 丛洪良 黄体钢 +4 位作者 周丽娟 宋昱 马向虹 王伟 刘洪梅 《South China Journal of Cardiology》 CAS 2001年第1期49-51,共3页
Objective To investigate the influence of captoprial and SNP on the release of ET -1 in cultured VSMC of rats. Methods Measurement of endothelin - 1 levels by radioimmljnoassay in various concentrations of captopril a... Objective To investigate the influence of captoprial and SNP on the release of ET -1 in cultured VSMC of rats. Methods Measurement of endothelin - 1 levels by radioimmljnoassay in various concentrations of captopril and/or sodium nitroprusside in cultured vascular smooth muscle cell (VSMC) of rats. Results Both captopril and SNP could reduce the high ET - 1 levels of VSMC which were caused by Ang Ⅱ. There was a linear relationship between Ang Ⅱlevels and ET -1 production ( r = 0. 760, P <0. 001 ) . Conclusion Endothelin - 1 may accelerate the formation and development of atherosclerosis through inhibiting endogenous NO production by VSMC. ACEI or NO inhibition of ET -1 release could reduce atherosclerosis formation. 展开更多
关键词 captorpil sodium nitroprusside endothelin - 1 nitric oxide VSMC
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Intracoronary nitroprusside in the prevention of the no-reflow phenomenon in acute myocardial infarction 被引量:22
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作者 PAN Wei WANG Lan-feng YU Jia-hui FAN Ying YANG Shu-sen ZHOU Li-jun LI Yue LI Wei-min 《Chinese Medical Journal》 SCIE CAS CSCD 2009年第22期2718-2723,共6页
Background No-reflow phenomenon during percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) is a predictive factor of continuous myocardial ischemia, ventricular remodeling and cardiac dy... Background No-reflow phenomenon during percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) is a predictive factor of continuous myocardial ischemia, ventricular remodeling and cardiac dysfunction, which is closely associated with a worse prognosis. This study aimed to evaluate intracoronary nitroprusside in the prevention of the no-reflow phenomenon in AMI.Methods Ninety-two consecutive patients with AMI, who underwent primary PCI within 12 hours of onset, were randomly assigned to 2 groups: intracoronary administration of nitroprusside (group A, n=46), intracoronary administration of nitroglycerin (group B, n=46). The angJographic results were observed. The real-time myocardial contrast echocardiography (RT-MCE), including contrast score index (CSI), wall motion score index (WMSI), transmural contrast defect length (CDL) and serious WM abnormal length (WML) were recorded at 24 hours and 1 week post-PCI. High sensitivity C-reactive protein (Hs-CRP) was examined by immune rate nephelometry. N-terminal prohormone brain natriuretic peptide (NT-proBNP) was tested with enzyme-linked immunosorbent assay. Patients were followed up for six months. Major adverse cardiac events (MACE) were recorded. Results The incidence of final TIMI-3 flow in group A was much higher than that in Group B (P 〈0.05), final corrected TIMI frame count (cTFC) in group A decreased significantly than that in group B (P 〈0.01). The CSI, CDL/LV length, WMSI and WL/LV length in group A were significantly lower than that in group B (P 〈0.01). Levels of Hs-CRP and NT-proBNP at 1 week post-PCI decreased significantly in group A than that in group B (P 〈0.01). Patients were followed up for 6 months and the incidence of MACE in group A was significantly lower than that in group B (P〈0.05).Conclusion Intracoronary nitroprusside can improve myocardial microcirculation, leading to the decrease of the incidence of no-reflow phenomenon and better prognosis. 展开更多
关键词 nitroprusside acute myocardial infarction no-reflow phenomenon prognosis
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Synthesis, Characterization and Crystal Structure of the First Tri-nuclear MFe_2 (M=Cu and Ni) Complexes Based on Nitroprusside
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作者 周北川 寇会忠 +2 位作者 李勇 熊明 王如骥 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2003年第9期1159-1164,共6页
Three new complexes [Ni(H2L)][Fe(CN)(5)(NO)](2)(.)6H(2)O (1), [Ni(H2L)][Fe(CN)(5)(NO)](2)(.)4H(2)O (2) and [Cu(H2L)][Fe-(CN)(5)(NO)](2)(.)4H(2)O (3) (L=3,10-bis(2-aminoethyl)-1,3,5, 8,10,12-hexaazacyclotetradecane) ar... Three new complexes [Ni(H2L)][Fe(CN)(5)(NO)](2)(.)6H(2)O (1), [Ni(H2L)][Fe(CN)(5)(NO)](2)(.)4H(2)O (2) and [Cu(H2L)][Fe-(CN)(5)(NO)](2)(.)4H(2)O (3) (L=3,10-bis(2-aminoethyl)-1,3,5, 8,10,12-hexaazacyclotetradecane) are prepared and characterized by IR, elemental analyses and single-crystal X-ray analyses, indicating that they are the first examples of trinuclear nitroprusside-bridged MFe2(M = Cu and Ni) complexes. In the three complexes, the central metal atoms (M) are all six-coordinated by the nitrogen atoms from the macrocyclic ligand and two cyano-bridges at the trans-positions to form distorted octahedral configurations. The axial N-M-N linkage is nearly vertical to the equatorial plane defined by four coordinating N atoms of macrocyclic ligand. The Cequivalent toN-Ni bond angle of 172.6degrees in complex 1 is apparently larger than those in complexes 2 and 3 (152.57degrees and 136.37degrees, respectively). The three complexes are all connected by hydrogen bonds into 3D networks. This study shows that the cyano-bridged trinuclear species could be generated via the control of the charge of the building blocks. 展开更多
关键词 copper complex nickel complex nitroprusside cyano bridge crystal structure
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Copper Nitroprusside-Based Electrochemical Sensor for Detection of Tryptophan
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作者 Pachanuporn Sunon Tidapa Rattanaumpa +5 位作者 Kornkanok Phakhunthod Keerakit Kaewket Pantipa Sawatmuenwai Suttipong Wannapaiboon Theeranun Siritanon Kamonwad Ngamchuea 《Journal of Analysis and Testing》 EI CSCD 2023年第4期405-415,共11页
This work presents a novel electrochemical approach for detecting tryptophan through its interaction with copper nitroprusside,which is synthesized using a simple chemical co-precipitation method.The utilization of th... This work presents a novel electrochemical approach for detecting tryptophan through its interaction with copper nitroprusside,which is synthesized using a simple chemical co-precipitation method.The utilization of the reduction reaction inherent to copper nitroprusside effectively exhibits high selectivity against common interferences present in urine,such as melatonin,lactate,cytosine,cytidine,urea,ascorbic acid,creatine,creatinine,tyrosine,glycine,alanine,arginine,and lysine.The method demonstrates two linear ranges:0.0-0.15 mmol/L and 0.15-2.0 mmol/L with the sensitivities of 119.7±0.2μA/(mmol/L)and 9.9±0.4μA/(mmol/L),respectively.The limit of detection(3S_(B)/m)was determined to be 5.5μmol/L.Application of the sensor in synthetic urine yielded the recovery of 103%±5%. 展开更多
关键词 Copper nitroprusside Prussian blue analog TRYPTOPHAN SENSOR VOLTAMMETRY
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Synergistic Effects of Nitric Oxide and Harvest Maturity on Quality of Honey Peach during Cold Storage
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作者 胡花丽 李鹏霞 +1 位作者 王毓宁 李志强 《Agricultural Science & Technology》 CAS 2013年第4期549-553,共5页
In this study, peaches of cv. 'Sui Yuan' with different maturities were treated with 0.05 mM sodium nitroprusside (SNP), a nitric oxide donor, for 5 min, at 28℃, and then stored at 0-1.5℃ for 30 days. Untreated ... In this study, peaches of cv. 'Sui Yuan' with different maturities were treated with 0.05 mM sodium nitroprusside (SNP), a nitric oxide donor, for 5 min, at 28℃, and then stored at 0-1.5℃ for 30 days. Untreated fruits stored under the same conditions were used as control fruits in the experiment. The browning level, activities of polyphenol oxidase (PPO), peroxydase (POD) and superoxide dismutase (SOD), and quality parameters (firmness, titratable acid, total soluble solids and total sugar) were analyzed. The results showed that the firmness of SNP-treated fruit at different stage of maturity were higher than that of the control fruit after storage for 30 days. However, no significant effect was found on total soluble solid content. The titratable acid content of low maturity fruit was higher in SNP-treated one than that of the control, but the titratable acid content of high maturity fruit treated by SNP was lower than that of the control on 10th and 30th day. In addition, the combination of SNP treatment and high maturity resulted in higher activities of SOD, lower activity of PPO and POD, lower browning level. Therefore, the combination of high maturity and SNP treatment might be a useful method to well maintain honey peach fruit quality during cold storage. 展开更多
关键词 Honey peach Harvest maturity Sodium nitroprusside treatment QUALITY
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Management of hypertensive crises in the elderly 被引量:3
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作者 Abbas Alshami Carlos Romero +1 位作者 America Avila Joseph Varon 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2018年第7期514-522,共9页
Hypertensive crises are elevations of blood pressure higher than 180/120 mmHg. These can be urgent or emergent, depending on the presence of end organ damage. The clinical presentation of hypertensive crises is quite ... Hypertensive crises are elevations of blood pressure higher than 180/120 mmHg. These can be urgent or emergent, depending on the presence of end organ damage. The clinical presentation of hypertensive crises is quite variable in elderly patients, and clinicians must be suspicious of non-specific symptoms. Managing hypertensive crises in elderly patients needs meticulous knowledge of the pathophysiological changes in them, pharmacological options, pharmacokinetics of the medications used, their side effects, and their interactions with other medications. Clevidipine, nicardipine, labetalol, esmolol, and fenoldopam are among the preferred choices in the elderly due to their efficacy and tolerability. Nitroprusside, hydralazine, and nifedipine should be avoided, unless there are no other options available, due to the high risk of complications and unpredictable responses. 展开更多
关键词 Beta-blockers Calcium channel blockers CLEVIDIPINE Elderly ESMOLOL FENOLDOPAM Hypertensive crises LABETALOL NICARDIPINE nitroprusside
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Alleviation of nickel toxicity in finger millet(Eleusine coracana L.)germinating seedlings by exogenous application of salicylic acid and nitric oxide 被引量:2
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作者 Kasi Viswanath Kotapati Bhagath Kumar Palaka Dinakara Rao Ampasala 《The Crop Journal》 SCIE CAS CSCD 2017年第3期240-250,共11页
This study investigated the effect of salicylic acid(SA) and sodium nitroprusside(SNP; NO donor) on nickel(Ni) toxicity in germinating finger millet seedlings. Fourteen-day-old finger millet plants were subjected to 0... This study investigated the effect of salicylic acid(SA) and sodium nitroprusside(SNP; NO donor) on nickel(Ni) toxicity in germinating finger millet seedlings. Fourteen-day-old finger millet plants were subjected to 0.5 mmol L^(-1) Ni overload and treated with 0.2 mmol L^(-1)salicylic acid and 0.2 mmol L^(-1)sodium nitroprusside to lessen the toxic effect of Ni.The Ni overload led to high accumulation in the roots of growing plants compared to shoots, causing oxidative stress. It further reduced root and shoot length, dry mass,total chlorophyll, and mineral content. Exogenous addition of either 0.2 mmol L^(-1)SA or0.2 mmol L^(-1)SNP reduced the toxic effect of Ni, and supplementation with both SA and SNP significantly reduced the toxic effect of Ni and increased root and shoot length,chlorophyll content, dry mass, and mineral concentration in Ni-treated plants. The results show that oxidative stress can be triggered in finger millet plants by Ni stress by induction of lipoxygenase activity, increase in levels of proline, O_2^(·-) radical, MDA, and H_2O_2, and reduction in the activity of antioxidant enzymes such as CAT, SOD, and APX in shoots and roots. Exogenous application of SA or SNP, specifically the combination of SA + SNP,protects finger millet plants from oxidative stress observed under Ni treatment. 展开更多
关键词 Finger MILLET Antioxidant ENZYMES Ni Salicylic acid Sodium nitroprusside
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Effects of a nitric oxide donor and nitric oxide scavengers on Sorbus pohuashanensis embryo germination 被引量:2
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作者 Ling Yang Dongyan Zhang +3 位作者 Hongnan Liu Cheng Wei Jianan Wang Hailong Shen 《Journal of Forestry Research》 SCIE CAS CSCD 2018年第3期628-635,共8页
The effects of an exogenous nitric oxide donor(sodium nitroprusside, SNP), a NO scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxode(PTIO) and carboxy-PTIO potassium salt(c PTIO) on the embryo germination ... The effects of an exogenous nitric oxide donor(sodium nitroprusside, SNP), a NO scavenger 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxode(PTIO) and carboxy-PTIO potassium salt(c PTIO) on the embryo germination of Sorbus pohuashanensis were studied in a petri dish test. SNP at 0.5–5 mmol L-1 increased germination percentage, mean time to germination, germination index and germination energy compared with the control to different degrees. Treatment with 2 mmol L-1 SNP improved germination most significantly; embryo germination percentage for mother tree 1(91.11%) and mother tree 2(64.44%) were much higher than the control. In addition,excessive SNP levels did not enhance embryo germination.Combined treatment with SNP and an NO scavenger delayed embryo germination. Treatment with c PTIO inhibited embryo germination; germination percentage was 42.22% and was lower than that of the control. These results show that low concentrations of exogenous NO can enhance the embryo germination of S. pohuashanensis,providing a simple, effective way for promoting germination of S. pohuashanensis. 展开更多
关键词 Mountain ash Embryo germination Nitric oxide Sodium nitroprusside Nitric oxide scavenger
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The effect of time and type of stress moderators on yield and yield components of cotton on conventional and double‑cropping systems under saline conditions 被引量:1
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作者 BORZOUYI Zeinab ARMIN Mohammad MARVI Hamid 《Journal of Cotton Research》 2021年第4期322-336,共15页
Background:Today,stress moderators are employed to mitigate crop loss due to the adverse effects of environmental stress.The current research aimed to investigate the impacts of time and stress moderator types on agro... Background:Today,stress moderators are employed to mitigate crop loss due to the adverse effects of environmental stress.The current research aimed to investigate the impacts of time and stress moderator types on agro-physiological responses of cotton on conventional and double-cropping systems during 2017 and 2018 under saline conditions.A split-plot factorial experiment was carried out in a randomized complete block design with three replications.Cultivation system[conventional(recommended planting date)and double-cropping systems(sowing after harvest of wheat)]were considered as the main plots,and stress moderator type at four levels[water control,2 mmol·L^(-1) Salicylic acid(SA),100 mmol·L^(-1) Glycine betaine(GB),and 100μmol·L^(-1) sodium nitroprusside(SNP)]and application time(flowering and flowering+bolling stages)were regarded as subplots.Results:Plant height,reproductive branch number,the number of bolls,10-boll weight,1000-seed weight,biological yield,seed cotton yield,lint yield,chlorophyll a,chlorophyll b,carotenoids,total chlorophyll,sodium,potassium,and proline content were less in double-cropping system comparing with conventional system.Spraying with the stress moderators alleviated soil salinity effects on yield,yield components,and biochemical traits of cotton.SNP spraying led to maximum plant height,branch number,the number of bolls per plant,10-boll weight and seed cotton yield.SA spraying yielded the highest 1000-seed weight,biological yield,lint percentage and lint yield.The highest chlorophyll a,chlorophyll b,carotenoids,and total chlorophyll content resulted from SNP spraying.Yield,yield components,and biochemical traits did not respond to the stress moderator types in double-cropping system.However,the highest chlorophyll a,carotenoids,proline content,the number of bolls per plant,and seed cotton yield resulted from SNP spraying in conventional system.No statistically significant differences were observed between spraying with SNP and SA in most studied traits.Conclusions:The results suggest that the optimum cotton planting time and SNP spraying could be recommended for producing the most suitable yield under saline conditions.Highlights:External application of stress modulators increases salinity stress tolerance.Spraying with sodium nitroprusside has more moderating effect.Agro-physiological response of cotton to moderators is stronger in early sowing.Maximum seed cotton yield was achieved at early sowing and spraying sodium nitroprusside.Delayed cultivation reduces cotton yield. 展开更多
关键词 COTTON Glycine betaine Salicylic acid SALINITY Sodium nitroprusside Sowing date
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