The phenomena of saltatory movements of intracellular particles (including organelles) in living cells have been repeatedly reported. The main feature of this kind of movement is the intermittency: the particle moves ...The phenomena of saltatory movements of intracellular particles (including organelles) in living cells have been repeatedly reported. The main feature of this kind of movement is the intermittency: the particle moves suddenly within a short duration of time and展开更多
A variety of riving cells possess particles undergoing saltatory movement, which is characterized by discontinuous jumps and can easily be observed under the fight microscope. Several detailed descriptions of the salt...A variety of riving cells possess particles undergoing saltatory movement, which is characterized by discontinuous jumps and can easily be observed under the fight microscope. Several detailed descriptions of the saltatory movement have been presented and it展开更多
Until now, nerve conduction has been described on the basis of equivalent circuit model and cable theory, both of which supposed closed electric circuits spreading inside and outside the axoplasm. With these conventio...Until now, nerve conduction has been described on the basis of equivalent circuit model and cable theory, both of which supposed closed electric circuits spreading inside and outside the axoplasm. With these conventional models, we can simulate the propagating pattern of action potential along the axonal membrane based on Ohm＇s law and Kirchhoff＇s law. However, we could not fully explain the different conductive patterns in unmyelinated and myelinated nerves with these theories. Also, whether we can really suppose closed electrical circuits in the actual site of the nerves or not has not been fully discussed yet. In this report, a recently introduced new theoretical model of nerve conduction based on electrostatic molecular interactions within the axoplasm will be reviewed. With this new approach, we can explain the different conductive patterns in unmyelinated and myelinated nerves. This new mathematical conductive model based on electrostatic compressional wave in the intracellular fluid may also be able to explain the signal integration in the neuronal cell body and the back-propagation mechanism from the axons to the dendrites. With this new mathematical nerve conduction model based on electrostatic molecular interactions within the intracellular fluid, we may be able to achieve an integrated explanation for the physiological phenomena taking place in the nervous system.展开更多
We analytically derived the complex Ginzburg-Landau equation from the Liénard form of the discrete FitzHugh Nagumo model by employing the multiple scale expansions in the semidiscrete approximation. The complex G...We analytically derived the complex Ginzburg-Landau equation from the Liénard form of the discrete FitzHugh Nagumo model by employing the multiple scale expansions in the semidiscrete approximation. The complex Ginzburg-Landau equation now governs the dynamics of a pulse propagation along a myelinated nerve fiber where the wave dispersion relation is used to explain the famous phenomena of propagation failure and saltatory conduction. Stability analysis of the pulse soliton solution that mimics the action potential fulfills the Benjamin-Feir criteria for plane wave solutions. Finally, results from our numerical simulations show that as the dissipation along the myelinated axon increases, the nerve impulse broadens and finally degenerates to front solutions.展开更多
文摘The phenomena of saltatory movements of intracellular particles (including organelles) in living cells have been repeatedly reported. The main feature of this kind of movement is the intermittency: the particle moves suddenly within a short duration of time and
文摘A variety of riving cells possess particles undergoing saltatory movement, which is characterized by discontinuous jumps and can easily be observed under the fight microscope. Several detailed descriptions of the saltatory movement have been presented and it
文摘Until now, nerve conduction has been described on the basis of equivalent circuit model and cable theory, both of which supposed closed electric circuits spreading inside and outside the axoplasm. With these conventional models, we can simulate the propagating pattern of action potential along the axonal membrane based on Ohm＇s law and Kirchhoff＇s law. However, we could not fully explain the different conductive patterns in unmyelinated and myelinated nerves with these theories. Also, whether we can really suppose closed electrical circuits in the actual site of the nerves or not has not been fully discussed yet. In this report, a recently introduced new theoretical model of nerve conduction based on electrostatic molecular interactions within the axoplasm will be reviewed. With this new approach, we can explain the different conductive patterns in unmyelinated and myelinated nerves. This new mathematical conductive model based on electrostatic compressional wave in the intracellular fluid may also be able to explain the signal integration in the neuronal cell body and the back-propagation mechanism from the axons to the dendrites. With this new mathematical nerve conduction model based on electrostatic molecular interactions within the intracellular fluid, we may be able to achieve an integrated explanation for the physiological phenomena taking place in the nervous system.
文摘We analytically derived the complex Ginzburg-Landau equation from the Liénard form of the discrete FitzHugh Nagumo model by employing the multiple scale expansions in the semidiscrete approximation. The complex Ginzburg-Landau equation now governs the dynamics of a pulse propagation along a myelinated nerve fiber where the wave dispersion relation is used to explain the famous phenomena of propagation failure and saltatory conduction. Stability analysis of the pulse soliton solution that mimics the action potential fulfills the Benjamin-Feir criteria for plane wave solutions. Finally, results from our numerical simulations show that as the dissipation along the myelinated axon increases, the nerve impulse broadens and finally degenerates to front solutions.
