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Cosmetology Incision in Treatment of Benign Tumor of Breast: A Report of 1000 Cases 被引量:1
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作者 Mingqiang Han Lixian Yang Shubo Chen 《International Journal of Clinical Medicine》 2015年第7期465-468,共4页
Objective: To explore the selection of the best incision for operative treatment of benign breast tumor. Methods: The clinical data of 1000 cases of benign breast tumor operated by cosmetology incision were retrospect... Objective: To explore the selection of the best incision for operative treatment of benign breast tumor. Methods: The clinical data of 1000 cases of benign breast tumor operated by cosmetology incision were retrospectively analyzed. Results: All patients underwent tumor resection and were satisfied with the incision. Conclusions: Benign breast tumor can be excised through cosmetology incision, and no obvious scar leaves behind, so it can satisfy the cosmetic requirement of many patients. 展开更多
关键词 benign BREAST tumor COSMETOLOGY INCISION CICATRIX
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Duodenum-preserving resection and Roux-en-Y pancreatic jejunostomy in benign pancreatic head tumors 被引量:7
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作者 Chun-Hui Yuan Ming Tao +3 位作者 Yi-Mu Jia Jing-Wei Xiong Tong-Lin Zhang Dian-Rong Xiu 《World Journal of Gastroenterology》 SCIE CAS 2014年第44期16786-16792,共7页
This study was conducted to explore the feasibility of partial pancreatic head resection and Roux-en-Y pancreatic jejunostomy for the treatment of benign tumors of the pancreatic head(BTPH). From November 2006 to Febr... This study was conducted to explore the feasibility of partial pancreatic head resection and Roux-en-Y pancreatic jejunostomy for the treatment of benign tumors of the pancreatic head(BTPH). From November 2006 to February 2009, four patients(three female and one male) with a mean age of 34.3 years(range: 21-48 years) underwent partial pancreatic head resection and Roux-en-Y pancreatic jejunostomy for the treatment of BTPH(diameters of 3.2-4.5 cm) using small incisions(5.1-7.2 cm). Preoperative symptoms include one case of repeated upper abdominal pain, one case of drowsiness and two cases with no obvious preoperative symptoms. All four surgeries were successfully performed. The mean operative time was 196.8 min(range 165-226 min), and average blood loss was 138.0 m L(range: 82-210 m L). The mean postoperative hospital stay was 7.5 d(range: 7-8 d). In one case, the main pancreatic duct was injured. Pathological examination confirmed that one patient suffered from mucinous cystadenoma, one exhibited insulinoma, and two patients had solid-pseudopapillary neoplasms. There were no deaths or complications observed during the perioperative period. All patients had no signs of recurrence of the BTPH within a follow-up period of 48-76 mo and had good quality of life without diabetes. Partial pancreatic head resection with Roux-en-Y pancreatic jejunostomy is feasible in selected patients with BTPH. 展开更多
关键词 PANCREATIC benign tumor PANCREATIC head Partial re
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Liver transplantation for benign liver tumors 被引量:3
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作者 Ana Ostojic Anna Mrzljak Danko Mikulic 《World Journal of Hepatology》 2021年第9期1098-1106,共9页
Benign liver tumors are common lesions that are usually asymptomatic and are often found incidentally due to recent advances in imaging techniques and their widespread use.Although most of these tumors can be managed ... Benign liver tumors are common lesions that are usually asymptomatic and are often found incidentally due to recent advances in imaging techniques and their widespread use.Although most of these tumors can be managed conservatively or treated by surgical resection,liver transplantation(LT)is the only treatment option in selected patients.LT is usually indicated in patients that present with life-threatening complications,when the lesions are diffuse in the hepatic parenchyma or when malignant transformation cannot be ruled out.However,due to the significant postoperative morbidity of the procedure,scarcity of available donor liver grafts,and the benign course of the disease,the indications for LT are still not standardized.Hepatic adenoma and adenomatosis,hepatic hemangioma,and hepatic epithelioid hemangioendothelioma are among the most common benign liver tumors treated by LT.This article reviews the role of LT in patients with benign liver tumors.The indications for LT and long-term outcomes of LT are presented. 展开更多
关键词 benign liver tumor Liver transplantation Hepatic adenoma Liver adenomatosis Hepatic hemangioma Hepatic epithelioid hemangioendothelioma
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Rarity among benign gastric tumors: Plexiform fibromyxoma-Report of two cases 被引量:1
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作者 Kinga Szurian Holger Till +4 位作者 Eva Amerstorfer Nicole Hinteregger Hans-Jorg Mischinger Bernadette Liegl-Atzwanger Iva Brcic 《World Journal of Gastroenterology》 SCIE CAS 2017年第31期5817-5822,共6页
Plexiform fibromyxoma is a very rare mesenchymal tumor of the stomach, found almost exclusively in the antrum/pylorus region. The most common presenting symptoms are anemia, hematemesis, nausea and unintentional weigh... Plexiform fibromyxoma is a very rare mesenchymal tumor of the stomach, found almost exclusively in the antrum/pylorus region. The most common presenting symptoms are anemia, hematemesis, nausea and unintentional weight loss, without sex or age predilection. We describe here two cases of plexiform fibromyxoma, involving a 16-year-old female and a 34-year-old male. Both patients underwent complete resection(R0) by distal gastrectomy and retrocolic gastrojejunostomy(according to Billroth 2); for both, the postoperative course was uneventful. Histology showed multiple intramural and subserosal nodules with characteristic plexiform growth, featuring bland spindle cells situated in an abundant myxoid stroma with low mitotic activity. Immunohistochemistry showed α-smooth muscle actin-positive spindle cells, focal positivity for CD10, and negative staining for KIT, DOG1, CD34, S100, β-catenin, STAT-6 and anaplastic lymphoma kinase. One of the cases showed focal positivity for h-caldesmon and desmin. Upon followup, no sign of disease was found. In the differential diagnosis of plexiform fibromyxoma, it is important to exclude the more common gastrointestinal stromal tumors as they have greater potential for aggressivebehavior. Other lesions, like neuronal and vascular tumors, inflammatory fibroid polyps, abdominal desmoid-type fibromatosis, solitary fibrous tumors and smooth muscle tumors, must also be excluded. 展开更多
关键词 Plexiform fibromyxoma Plexiform angiomyxoid myofibroblastic 肿瘤 胃肠的 stromal 肿瘤 良性的胃的肿瘤
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Detecting benign uterine tumors by autofuorescence lifetime imaging microscopy through adjacent healthy cervical tissues
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作者 Maojia Huang Zixiao Zhang +7 位作者 Xinyi Wang Yonghui Xie Yiyan Fei Jiong Ma Jing Wang Li Chen Lan Mi Yulan Wang 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2019年第5期105-115,共11页
The endogenous fluorophores such as reduced nicotinarmide adenine dinucleotide(phosphate)(NAD(P)H)and favin adenine dinucleotide(FAD)in cells and tissues can be imaged by fuo-rescence lifetime imaging microscopy(FLIM)... The endogenous fluorophores such as reduced nicotinarmide adenine dinucleotide(phosphate)(NAD(P)H)and favin adenine dinucleotide(FAD)in cells and tissues can be imaged by fuo-rescence lifetime imaging microscopy(FLIM)to show the tisute morphology features,as well as the biomolecular changes in microenvironment.The two important coenzymes in cellular metabolism,NAD(P)H and FAD,can be used to monitor the cellular metabolic status.This work proposed a novel method to study the uterine metabolism at the adjacent site of healthy cervix.It was found that the benign uterine tumors such as leiomyomas and adenomyosis with abnormal cell growth can be detected by measuring the fluorescence lifetime of NAD(P)H and FAD in adjacent healthy cervical tisues.This method opened a novel strategy for alicted women to undergo the cervical biopsies instead of hysterectomies for detecting tumors,which can preserve the fertility of patients.The FLIM studying on NAD(P)H and FAD indicated the correlation between metabolism and some diseases,including diabetes,hyperthyroidism and obesity.It was also suggested that the metabolic level might be quite different for a patient with a malignant tumnor history. 展开更多
关键词 Autofuorescence fuorescence lifetime imaging benign uterine tumor metabolism
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Frequency of Benign and Malignant Tumors in Localized Vitiligo in Comparison to Generalized and Universal Vitiligo
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作者 Khalifa E. Sharquie Adil A. Noaimi Sadiq J. Murtada 《Journal of Cosmetics, Dermatological Sciences and Applications》 2016年第4期133-139,共7页
Background: Autoimmune diseases like pemphigus and systemic lupus erythematosus are protective against skin malignancies like basal cell carcinoma and squamous cell carcinoma. Objective: As vitiligo is an autoimmune d... Background: Autoimmune diseases like pemphigus and systemic lupus erythematosus are protective against skin malignancies like basal cell carcinoma and squamous cell carcinoma. Objective: As vitiligo is an autoimmune diseases, the aim of the present work is to record the frequency of all benign and malignant skin tumors among patients with different severity of vitiligo and to be compared with the skin tumors in healthy control. Patients and Methods: This is a case series, descriptive study done in the Department of Dermatology—Baghdad Teaching Hospital, Baghdad, Iraq, during the period from May 2014-May 2015. History was taken from each patient with vitiligo regarding age, gender, duration, personal and family history of vitiligo and other autoimmune diseases such as diabetes mellitus, thyroid dysfunction, and alopecia areata. Patients were assessed for past and present history of photodermatosis and any skin cancers. Healthy control was considered. Results: Three hundred and fifty patients with vitiligo were included in this study: 50 patients with universal vitiligo, 100 patients with generalized vitiligo, and 200 patients with localized vitiligo as well as 500 subjects as a healthy control. The ages of all studied subjects ranged between 31 and 77 years. Twenty four(48%) patients with universal vitiligo were males and 26 (52%) were females;49(49%) patients with generalized vitiligo were males and 51(51%) were females;101(50.5%) patients with localized vitiligo were males and 99(49.5%) were females and 235(47%) of control were males and 265(53%) were females. All skin tumors were seen to be high in healthy subjects and lower or absent in patients with vitiligo. Also patients with mild vitiligo had a higher frequency of skin tumors including benign and malignant than patients with severe vitiligo especially in patients with universal vitiligo. In addition, no photosensitivity or actinic reticuloid was detected in patients with vitiligo. Conclusions: Vitiligo especially generalized and universal type as an autoimmune disease had a protective action against photodamage, photosensitivity and skin tumors whether benign or malignant. 展开更多
关键词 VITILIGO PHOTODAMAGE PHOTOPROTECTION benign and Malignant tumors
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Clinical Significance of Serum IL-18 and IL-18BP in Patients with Benign or Malignant Primary Liver Tumors 被引量:1
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作者 Chengnong Guan Xianghui Liao Haiqing Lou Xingming Chen Bao Ying Chen Peiweng Zhang 《Clinical oncology and cancer resexreh》 CAS CSCD 2009年第4期282-285,共4页
OBJECTIVE To study the relationship between the serumlevels of IL-18 and IL-18BP in the development and growth ofprimary liver cancer,benign liver tumors and liver cirrhosis and todetermine the value of serum IL-18 an... OBJECTIVE To study the relationship between the serumlevels of IL-18 and IL-18BP in the development and growth ofprimary liver cancer,benign liver tumors and liver cirrhosis and todetermine the value of serum IL-18 and IL-18BP in the diagnosisof primary liver cancer.METHODS The serum levels of IL-18 and IL-18BP in 36 patientswith primary hepatic carcinoma(PHC)were detected.Eighteenpatients were diagnosed with various benign liver tumors and 21patients with cirrhosis of liver(LC),determined by using an ELISAassay.The serum levels of AFP in 36 patients with primary livercancer were examined.The relationship among levels of serumIL-18,IL-18BP and AFP in the primary liver cancer was explored.RESULTS The sIL-18 levels in PHC were significantly lower thanin control group,the benign liver tumor group and the LC group.The sIL-18BP in PHC was significantly higher than that in controlgroup,benign liver tumor group and LC group(P<0.001).Therewas a close correlation between the levels of IL-18,IL-18BP andclinical stage in PHC:the later clinical stages had lower levels ofIL-18 and higher levels of IL-18BP while the earlier clinical stageshad higher levels of IL-18 and lower levels of IL-18BP.There was anegative correlation between serum levels of IL-18 and AFP in thePHC group(r = -0.7152,n=36,P<0.01),and there was a positivecorrelation between serum levels of IL-18 BP and AFP in thepatients with PHC(r=0.6315,n=36,P<0.01).The IL-18 and IL-18BP in the patients with various benign liver tumors or LC weresignificantly higher than those in control group.The differenceswere statistically significant(P<0.01).CONCLUSION Serum levels of IL-18 and IL-18BP can reflectthe immune function of patients with primary liver cancer,withvarious benign liver tumors or with LC and can also be indicativeof the clinic stage of primary liver cancer.It can be used to assistin making a diagnosis and in determining the clinical stage ofPHC.Detecting AFP concurrently can help make the diagnosis ofprimary liver cancer more precise. 展开更多
关键词 肝癌 IL-18 IL-18BP 肝硬化
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显微镜下保留睾丸的睾丸良性肿瘤切除术临床疗效分析(附16例报道)
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作者 于磊 赵静 +10 位作者 王洪强 周沛红 门建华 王刚 李强 潘瑜 李文鑫 钱林 李慎谦 王沛涛 荆涛 《中华男科学杂志》 CAS CSCD 2024年第3期209-216,共8页
目的:探讨显微外科手术技术应用于保留睾丸的睾丸良性肿瘤切除术的安全性及临床疗效。方法:回顾性分析2020年10月至2023年2月青岛大学附属医院男科收治的16例睾丸肿瘤患者的病例资料。患者中位年龄23岁,睾丸肿瘤均为单侧,左侧7例,右侧9... 目的:探讨显微外科手术技术应用于保留睾丸的睾丸良性肿瘤切除术的安全性及临床疗效。方法:回顾性分析2020年10月至2023年2月青岛大学附属医院男科收治的16例睾丸肿瘤患者的病例资料。患者中位年龄23岁,睾丸肿瘤均为单侧,左侧7例,右侧9例,睾丸肿瘤最长径1.0~3.5 cm(中位数1.85 cm)。患者均在术前完善阴囊彩超(CDFI)、磁共振(MRI)、精液、血清睾酮、甲胎蛋白(AFP)、人绒毛膜促性腺激素(hCG)、乳酸脱氢酶(LDH)检查。16例患者均行显微镜下保留睾丸的睾丸肿瘤切除术(TSMS),术中运用显微外科技术,精准辨别睾丸内肿瘤与正常睾丸组织的边界,距离肿瘤边界约2 mm完整切除肿瘤及少部分邻近正常睾丸组织,使用显微双极电凝镊给予精确止血,最大限度保留正常睾丸组织。将完整切除的睾丸内肿瘤及邻近正常睾丸组织进行快速冰冻病理检查。术后定期复查CDFI、MRI、精液、血清睾酮等项目。结果:16例患者术前血清睾酮、AFP、hCG、LDH及精液检查指标均在正常参考值范围内。所有16例患者的术中快速冰冻病理依据2022年最新版WHO泌尿及男性生殖系统肿瘤分类标准,均诊断为睾丸良性肿瘤,并顺利完成TSMS治疗。16例患者术后康复顺利,术后1个月复查CDFI提示睾丸剩余组织血供良好,所有患者随访14~40个月,随访期内定期复查CDFI和MRI均未见睾丸内肿瘤残留、复发或转移征象,血清睾酮、AFP、hCG、LDH及精液检查较术前无显著变化,2例育龄期患者的配偶分别于术后16、18个月实现自然受孕。结论:睾丸内良性肿瘤可以通过CDFI、MRI检查进行术前鉴别诊断,最终定性诊断仍需组织病理检查。TSMS运用显微外科手术技术,可以在完整切除睾丸内肿瘤的前提下最大限度保留正常睾丸组织,从而有效保存男性生育力。TSMS疗效良好、安全性高,特别适用于有保留生育力需求的患者。 展开更多
关键词 显微外科 保留睾丸手术 睾丸良性肿瘤 生育力保存
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IL-35、Beclin-1在乳腺癌患者外周血中的水平及意义
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作者 宦宇 黄秋兰 +5 位作者 齐结华 赵斌奇 蔡徐山 吴守乐 张春利 戴清清 《检验医学与临床》 CAS 2024年第12期1683-1686,共4页
目的探讨白细胞介素(IL)-35、自噬相关蛋白Beclin-1在乳腺癌患者外周血中的水平及意义。方法选取2022年5-10月在上海市嘉定区妇幼保健院诊治的原发性乳腺癌女性患者44例(乳腺癌组)、乳腺良性肿瘤女性患者40例(乳腺良性肿瘤组)及体检的... 目的探讨白细胞介素(IL)-35、自噬相关蛋白Beclin-1在乳腺癌患者外周血中的水平及意义。方法选取2022年5-10月在上海市嘉定区妇幼保健院诊治的原发性乳腺癌女性患者44例(乳腺癌组)、乳腺良性肿瘤女性患者40例(乳腺良性肿瘤组)及体检的健康者40例(健康对照组)作为研究对象。采用酶联免疫吸附试验检测并比较各组外周血中IL-35和Beclin-1水平,同时检测乳腺癌患者糖类抗原15-3(CA15-3),比较不同临床病理特征的乳腺癌患者IL-35、Beclin-1、CA15-3水平;分析乳腺癌患者外周血IL-35、Beclin-1、CA15-3水平之间的相关性。结果乳腺癌组和乳腺良性肿瘤组外周血IL-35水平均高于健康对照组(P<0.05),Beclin-1水平均低于健康对照组(P<0.05)。乳腺癌组外周血IL-35水平高于乳腺良性肿瘤组(P<0.05),Beclin-1水平低于乳腺良性肿瘤组(P<0.05)。不同病理分级、淋巴结转移情况的乳腺癌患者外周血IL-35、Beclin-1水平比较,差异均有统计学意义(P<0.05);不同雌激素受体(ER)检测结果的乳腺癌患者外周血IL-35水平比较,差异无统计学意义(P>0.05),而Beclin-1水平比较,差异有统计学意义(P<0.05)。乳腺癌患者外周血IL-35水平与Beclin-1水平呈负相关(r=-0.484,P<0.05);IL-35、Beclin-1水平与CA15-3水平均无相关性(均P>0.05)。结论乳腺癌患者外周血IL-35水平升高、Beclin-1水平降低。不同病理分级、淋巴结转移情况的乳腺癌患者外周血IL-35、Beclin-1水平有明显差异。乳腺癌患者外周血IL-35水平与Beclin-1水平呈负相关,而IL-35、Beclin-1水平与肿瘤标志物CA15-3水平均无关。 展开更多
关键词 白细胞介素-35 BECLIN-1 乳腺癌 糖类抗原15-3 乳腺良性肿瘤
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基于瘤体及瘤周多参数MRI对乳腺病变良恶性诊断列线图预测模型的构建与评价
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作者 张春福 彭波 +4 位作者 黄崎 张雪峰 才春红 海洋 张巍巍 《陕西医学杂志》 CAS 2024年第1期72-76,共5页
目的:建立基于瘤体及瘤周多参数MRI的乳腺病变良恶性鉴别诊断的列线图模型,并验证其预测效能。方法:纳入经病理学检查明确乳腺病变性质的100例患者作为研究对象,所有患者均行核磁共振(MRI)检查和病理检查,根据病理检查结果分为乳腺良性... 目的:建立基于瘤体及瘤周多参数MRI的乳腺病变良恶性鉴别诊断的列线图模型,并验证其预测效能。方法:纳入经病理学检查明确乳腺病变性质的100例患者作为研究对象,所有患者均行核磁共振(MRI)检查和病理检查,根据病理检查结果分为乳腺良性病变组(n=62)和乳腺恶性病变组(n=38)。收集患者临床资料、瘤体各参数、瘤周各参数以及乳腺病变良恶性情况。多因素Logistic回归分析筛选乳腺恶性病变的危险因素并构建列线图预测模型,采用受试者工作特征(ROC)曲线和Hosmer-Lemeshow拟合优度检验验证模型的预测效能及拟合优度;内部验证采用Bootstrap。结果:乳腺恶性病变组病灶直径、平均扩散峰度(MK)、MDp/t、瘤周与瘤体MKp/n高于乳腺良性病变组(均P<0.05);乳腺恶性病变组表观扩散系数(ADC)值、平均扩散率(MD)、非对称磁化转移率(MTRasym)、MKp/t、MDp/n低于乳腺良性病变组(均P<0.05)。多因素分析结果显示,病灶直径、MK、MDp/t、MKp/n升高,ADC值、MD、MTRasym、MKp/t、MDp/n降低是乳腺恶性病变的独立影响因素(均P<0.05)。基于上述独立影响因素构建乳腺恶性病变的列线图预测模型,曲线下面积(AUC)为0.827。Hosmer-Lemeshow拟合优度检验显示P值为0.004。采用Bootstrap法,生成的校准曲线拟合良好。结论:瘤体及瘤周多参数MRI对乳腺病变良恶性鉴别诊断具有重要预测价值,基于乳腺恶性病变的独立影响因素构建的列线图预测效果良好,能直观预测乳腺发生恶性病变的概率。 展开更多
关键词 乳腺病变 良恶性 鉴别诊断 瘤体参数 瘤周参数 核磁共振 列线图
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Nasal Dermoid Cyst with Sinus Tract Intranasal Bone: A Case Report
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作者 Sultan Kadasah Abdullah Alhelali +5 位作者 Saud Aldhabaan Abdulaziz Al Qahtani Abdullah Musleh Ali Alshahrani Shahd Dlboh Sahar Al-Otaibi 《International Journal of Otolaryngology and Head & Neck Surgery》 2024年第2期149-156,共8页
Dermoid cysts are benign tumors originating from germ cells, which can form in various locations, including the nasal area in rare cases. They are of unknown exact etiology, but it is suggested that it is due to abnor... Dermoid cysts are benign tumors originating from germ cells, which can form in various locations, including the nasal area in rare cases. They are of unknown exact etiology, but it is suggested that it is due to abnormal tissue migration during early embryonic development. Nasal dermoid cysts albeit rare, can present in various forms such as sinuses, fistulas, or intracranially extending tracts. They can be asymptomatic and incidentally discovered or present with a visible external mass or sinus that is either painful, infected or cosmetically concerning. If nasal dermoid cysts with an intra-nasal bone sinus tract are left untreated, they can lead to life-threatening complications. This report describes the case of a 6-year-old girl with a nasal dermoid cyst connected to a superficial punctum by an intra-nasal tract. She had undergone surgical excision of a nasal swelling previously diagnosed as a dermoid cyst. One year later, she returned to our clinic with a recurrence of the nasal swelling. Imaging tests revealed a nasal dermoid cyst with a tract extending to the nasal tip, without intracranial expansion. The cyst, along with the entire tract, was successfully removed surgically, and the postoperative follow-up indicated no complications. Histopathology confirmed the diagnosis of a dermoid cyst. This case underscores the significance of considering the dermoid tract in nasal cyst cases and the necessity of its complete removal to prevent recurrence. 展开更多
关键词 Dermoid Cyst Nasal Sinus Sinus Tract Intranasal Bone benign tumor Congenital Anomaly
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经乳晕切口真空辅助微创旋切系统治疗乳腺良性肿瘤的临床效果
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作者 郭晓龙 田亮 《妇儿健康导刊》 2024年第5期81-83,87,共4页
目的探讨经乳晕切口真空辅助微创旋切系统治疗乳腺良性肿瘤的临床效果。方法选取2022年1月至12月淄博市妇幼保健院乳腺甲状腺外科收治的100例乳腺良性肿瘤患者为研究对象,按照奇偶数法分为两组,每组50例。参比组采用传统开放手术治疗,... 目的探讨经乳晕切口真空辅助微创旋切系统治疗乳腺良性肿瘤的临床效果。方法选取2022年1月至12月淄博市妇幼保健院乳腺甲状腺外科收治的100例乳腺良性肿瘤患者为研究对象,按照奇偶数法分为两组,每组50例。参比组采用传统开放手术治疗,观察组采用经乳晕切口真空辅助微创旋切系统治疗,比较两组的治疗效果。结果观察组手术时间短于参比组,出血量少于参比组,手术切口长度短于参比组(P<0.05);观察组术后疼痛时间、切口愈合时间、住院时间短于参比组(P<0.05);观察组并发症总发生率低于参比组(P<0.05)。结论经乳晕切口真空辅助微创旋切系统治疗乳腺良性肿瘤的临床效果显著,值得推广。 展开更多
关键词 经乳晕切口 真空辅助 微创旋切系统 乳腺良性肿瘤
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1例十二指肠Brunner腺瘤内镜下黏膜切除术治疗实践
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作者 郭英允 任晓旭 +2 位作者 马明 刘宇 马君 《中国药业》 CAS 2024年第S01期124-126,共3页
目的为十二指肠Brunner腺瘤的临床合理治疗提供参考。方法对1例十二指肠Brunner腺瘤进行诊疗,给予内科常规护理,完善各项化验检查;并根据患者的病情及其要求,于2021年10月31日行内镜下黏膜切除术(尼龙圈结扎、圈套器辅助、高频电切除)... 目的为十二指肠Brunner腺瘤的临床合理治疗提供参考。方法对1例十二指肠Brunner腺瘤进行诊疗,给予内科常规护理,完善各项化验检查;并根据患者的病情及其要求,于2021年10月31日行内镜下黏膜切除术(尼龙圈结扎、圈套器辅助、高频电切除)。结果疗效较好,无明显出血或穿孔,手术风险和治疗成本均较低;术后3个月复查发现,胃镜能顺利穿过幽门管、十二指肠腔,且患者无任何腹胀、呕吐等不良反应,体质量增加了8 kg。结论十二指肠Brunner腺瘤内镜下黏膜切除术创伤小,并发症少,安全有效。 展开更多
关键词 十二指肠BRUNNER腺瘤 良性肿瘤 内镜下黏膜切除术
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经乳晕切口乳腺良性肿瘤切除术中腺体残端处理方式对疗效的影响
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作者 王畏 王滔 +2 位作者 张磊 张立功 张杰 《局解手术学杂志》 2024年第4期315-318,共4页
目的 比较经乳晕切口乳腺良性肿瘤切除术中采取旷置腺体残端与缝合腺体残腔两种处理方式的临床疗效。方法 选取2020年7月至2022年6月蚌埠医学院第二附属医院肿瘤外科收治的82例乳腺良性肿瘤患者,均行经乳晕切口乳腺良性肿瘤切除术。根... 目的 比较经乳晕切口乳腺良性肿瘤切除术中采取旷置腺体残端与缝合腺体残腔两种处理方式的临床疗效。方法 选取2020年7月至2022年6月蚌埠医学院第二附属医院肿瘤外科收治的82例乳腺良性肿瘤患者,均行经乳晕切口乳腺良性肿瘤切除术。根据术中处理方式的不同分为旷置腺体残端组(42例)和缝闭腺体残腔组(40例)。比较2组患者手术时间、术中出血量、拆线时间、硬块吸收时间、切口愈合率、乳房变形率、术后出血发生率、术后12个月肿瘤复发率及术后6 h、12 h、24 h的疼痛视觉模拟量表(VAS)评分。结果 2组患者手术时间、术中出血量、拆线时间比较差异均无统计学意义(P>0.05);旷置腺体残端组硬块吸收时间显著短于缝闭腺体残腔组,差异有统计学意义(P<0.05)。旷置腺体残端组乳房变形率显著低于缝闭腺体残腔组,差异有统计学意义(P<0.05)。2组患者切口愈合率、术后出血发生率、肿瘤复发率、术后24 h的VAS评分比较差异均无统计学意义(P>0.05)。结论 经乳晕切口乳腺良性肿瘤切除术中旷置腺体残端能加速硬块吸收,保持很好的乳腺外形,值得临床推广。 展开更多
关键词 经乳晕切口 乳腺良性肿瘤 腺体残端
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基于CT影像的人工智能在肾上腺良性肿瘤中的应用进展
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作者 朴则宇 刘婷婷 +1 位作者 孟名柱 贾中芝(审校) 《国际医学放射学杂志》 2024年第1期79-82,共4页
CT是诊断肾上腺良性肿瘤的重要手段,但仍有少部分肾上腺良性肿瘤难以确诊。人工智能(AI)可以运用计算机算法模仿人脑且具有学习和解决问题等任务的能力,包括机器学习和深度学习,已广泛应用于肾上腺良性肿瘤的诊断、鉴别诊断及治疗。就... CT是诊断肾上腺良性肿瘤的重要手段,但仍有少部分肾上腺良性肿瘤难以确诊。人工智能(AI)可以运用计算机算法模仿人脑且具有学习和解决问题等任务的能力,包括机器学习和深度学习,已广泛应用于肾上腺良性肿瘤的诊断、鉴别诊断及治疗。就目前基于CT影像的人工智能在肾上腺良性肿瘤中的应用进展进行综述。 展开更多
关键词 肾上腺 良性肿瘤 人工智能 体层摄影术 X线计算机 影像组学 深度学习
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A retrospective study of 2228 cases with eyelid tumors 被引量:8
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作者 Sha-Sha Yu Yun Zhao +2 位作者 Hong Zhao Jin-Yong Lin Xin Tang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2018年第11期1835-1841,共7页
AIM: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015. METHODS: In this retrospective study, a total of 2228 cases of eyelid tumors with patho... AIM: To describe the histopathologic and clinical features of eyelid tumor cases from Tianjin Eye Hospital during 2002 to 2015. METHODS: In this retrospective study, a total of 2228 cases of eyelid tumors with pathologic diagnoses were enrolled. The eyelid tumors were classified into three groups according to tumor origin: epidermal, adnexal and miscellaneous, including melanocytic, neural and vascular lesions. Inflammatory tumor-like lesions were excluded. The clinical characteristics of the eyelid tumors were analyzed, including age, gender and lesion location. RESULTS: Most eyelid tumors were epidermal in origin(1080, 48.5%), followed by miscellaneous(885, 39.7%) and adnexal tumors(263, 11.8%). Among all the tumors, 292(13.1%) were malignant lesions, 1910(85.7%) benign and 26(1.1%) premalignant lesions. Most malignant tumors originated from epidermal cells(60.0%), followed by adnexal cells(34.6%). The most common malignant tumors were basal cell carcinomas(56.5%) followed by sebaceous carcinoma(34.6%), squamous cell carcinomas(3.8%) and lymphoma/plasmocytoma(1.7%). The benign and premalignant eyelid lesions mostly originated from epidermal cells(46.4%) followed by miscellaneous cell sources(45.2%), including melanocytic nevus(33.8%), seborrheic keratosis(13.7%), squamous cell papilloma(13.0%) and epidermal cysts(11.5%). CONCLUSION: Eyelid tumors are mostly epithelial in origin. Benign tumors are significantly more common than malignant tumors with an obvious female predominance, and the most frequent malignant tumor are basal cell carcinoma, sebaceous carcinoma and squamous cell carcinomas. The tumor clinical features varied among the different subtypes. 展开更多
关键词 eyelid tumors benign tumors malignant tumor basal cell carcinoma sebaceous carcinoma squamous cell carcinoma melanocytic nevus
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冷热联合消融技术治疗气道良性肿瘤效果及预后影响因素分析
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作者 杨东明 许东风 +1 位作者 任蔚 任中海 《现代肿瘤医学》 CAS 2024年第2期276-280,共5页
目的:分析冷热联合消融技术治疗气道良性肿瘤的效果及预后影响因素,并构建列线图模型对其进行预测。方法:选取我院2016年1月-2022年5月收治的246例气道良性肿瘤患者,并接受消融技术治疗,根据预后不同分为狭窄组(n=36)与未狭窄组(n=210)... 目的:分析冷热联合消融技术治疗气道良性肿瘤的效果及预后影响因素,并构建列线图模型对其进行预测。方法:选取我院2016年1月-2022年5月收治的246例气道良性肿瘤患者,并接受消融技术治疗,根据预后不同分为狭窄组(n=36)与未狭窄组(n=210)。通过单因素、多因素分析气道良性肿瘤患者预后的影响因素;用R统计软件构建良性肿瘤预后的列线图预测模型,通过计算一致性指数(C-index)、构建校准图和受试者工作特征曲线(ROC)评价该模型的准确性及预测能力。结果:246例气道良性肿瘤患者接受消融技术治疗3个月内有36例(14.63%)出现气道狭窄,210例(85.37%)未出现气道狭窄;单因素分析显示,两组糖尿病史、高血压史、手术方式、感染、术后狭窄段气管直径比较,差异有统计学意义(P<0.05);Logistic回归分析显示,糖尿病史、高血压史、手术方式、感染、术后狭窄段气管直径均是气道良性肿瘤患者预后的危险因素(P<0.05);列线图预测气道良性肿瘤预后校准曲线与实际曲线基本吻合。结论:气道良性肿瘤患者预后的危险因素包括糖尿病史、高血压史、手术方式、感染、术后狭窄段气管直径,列线图模型对其预测具有较好的区分度和准确性。 展开更多
关键词 冷热联合消融技术 气道良性肿瘤 影响因素
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多孔腹腔镜手术与开腹手术治疗妊娠早中期卵巢良性肿瘤蒂扭转的效果及对妊娠结局的影响
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作者 王瑶 陈琳琳 段微 《临床和实验医学杂志》 2024年第5期512-515,共4页
目的探讨多孔腹腔镜手术(MILS)与开腹手术在治疗妊娠早中期卵巢良性肿瘤蒂扭转(BOTT)的效果及对妊娠结局的影响。方法将2013年2月至2023年1月首都医科大学附属北京妇产医院及清华大学第一附属医院收治的92例妊娠早中期BOTT孕妇纳入本次... 目的探讨多孔腹腔镜手术(MILS)与开腹手术在治疗妊娠早中期卵巢良性肿瘤蒂扭转(BOTT)的效果及对妊娠结局的影响。方法将2013年2月至2023年1月首都医科大学附属北京妇产医院及清华大学第一附属医院收治的92例妊娠早中期BOTT孕妇纳入本次回顾性研究,根据手术方式的不同分为开腹组(n=40)和MILS组(n=52)。比较2组患者围术期指标[包括肿瘤直径、扭转角度、缺血等级、手术时间、术中出血量、术后通气时间和住院时间]、术后病理结果、并发症发生情况和妊娠结局。结果2组的肿瘤直径、缺血等级比较,差异均无统计学意义(P>0.05);MILS组的扭转角度、手术时间、术中出血量、排气时间和住院时间分别为(436.0±189.0)°、(50.73±20.19)min、(18.84±5.42)mL、(16.48±7.08)h和(5.23±1.32)d,均显著低于开腹组[(590.0±202.0)°、(69.41±25.63)min、(46.61±18.30)mL、(26.05±12.57)h和(7.78±1.20)d],差异均有统计学意义(P<0.05)。妊娠早中期BOTT患者病理检查结果可知:占比最高的是黄体囊肿,其次是成熟畸胎瘤和单纯性囊肿,2组的术后病理检查结果差异无统计学意义(P>0.05)。2组术后并发症发生率比较,差异无统计学意义(P>0.05)。2组的早产、流产、引产、分娩方式、分娩孕周和新生儿出生体重比较,差异均无统计学意义(P>0.05)。结论MILS治疗妊娠早中期BOTT的术后并发症发生情况和妊娠结局与开腹手术治疗相当,但MILS手术效果优于开腹组。 展开更多
关键词 腹腔镜手术 妊娠早中期 卵巢良性肿瘤蒂扭转 妊娠结局
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经皮穴位电刺激联合音乐疗法对乳腺良性肿瘤手术患者的影响 被引量:1
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作者 王绚 赵庆盼 梁冰 《临床研究》 2024年第4期102-105,共4页
目的对乳腺良性肿瘤全麻手术患者行经皮穴位电刺激(TEAS)联合音乐疗法的效果进行分析。方法选取河南中医药大学第一附属医院2020年3月至2023年7月160例乳腺良性肿瘤患者为研究对象。运用随机抽样法分组研究,对照组以安慰治疗,TEAS组以T... 目的对乳腺良性肿瘤全麻手术患者行经皮穴位电刺激(TEAS)联合音乐疗法的效果进行分析。方法选取河南中医药大学第一附属医院2020年3月至2023年7月160例乳腺良性肿瘤患者为研究对象。运用随机抽样法分组研究,对照组以安慰治疗,TEAS组以TEAS治疗,五音疗法组以五音疗法治疗,联合组组以五音疗法联合TEAS治疗,各40例,治疗后对各组患者焦虑抑郁情绪、麻醉用量、疼痛情况、术后恢复等情况进行对比。结果术前30 min比较,四组患者汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)评分,差异无统计学意义(P>0.05),干预30 min后、入手术室时、术后评分经对比,差异均有统计学意义(P<0.05),联合组低于其他三组,对照组最高,差异均有统计学意义(P<0.05);麻醉用量对比,四组差异有统计学意义(P<0.05),以联合组低于五音疗法组、TEAS组、对照组;而不同时间段视觉模拟评分法(VAS)评分对比,拔管时差异无统计学意义(P>0.05),术后6 h、12 h、24 h经对比差异均有统计学意义(P<0.05),以联合组低于C、T、五音疗法组,对照组VAS评分最高;对比术后恢复质量评估量表(PQRS)评分,术前差异无统计学意义(P>0.05),术后差异有统计学意义(P<0.05),联合组最高,对照组低于其他三组。结论TEAS联合五行音乐适于乳腺良性肿瘤患者应用,缓解了焦虑、抑郁情绪,减少了麻醉用量同时缓解了疼痛情况,从而有利于术后恢复。 展开更多
关键词 乳腺良性肿瘤 经皮穴位电刺激 音乐疗法 麻醉效果
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不同手术切口对腮腺良性肿瘤患者血清疼痛介质、氧化应激的影响
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作者 王文明 侯明 Kapeishi 《河南医学研究》 CAS 2024年第9期1640-1644,共5页
目的分析不同手术切口对腮腺良性肿瘤患者血清疼痛介质、氧化应激的影响。方法回顾性分析2016年1月至2023年1月在赞比亚Ndola教学医院、赞比亚恩都拉铜带大学教学医院、河南省人民医院、河南科技大学第二附属医院接受腮腺良性肿瘤切除... 目的分析不同手术切口对腮腺良性肿瘤患者血清疼痛介质、氧化应激的影响。方法回顾性分析2016年1月至2023年1月在赞比亚Ndola教学医院、赞比亚恩都拉铜带大学教学医院、河南省人民医院、河南科技大学第二附属医院接受腮腺良性肿瘤切除手术治疗的65例腮腺良性肿瘤患者临床资料,按照手术切口分为对照组(40例,术中接受传统S形切口操作)、观察组[25例,术中行改良耳前-耳后发际切口(又称改良V形切口)]。对比两组手术指标、术区面神经损伤情况、血清疼痛介质、氧化应激指标、手术瘢痕情况、并发症发生率。结果观察组手术用时、术后引流量与对照组相比,差异无统计学意义(P>0.05);观察组术中出血量比对照组少(P<0.05);观察组术后第7天House-Brackmann分级法评分、超氧化物歧化酶、谷胱甘肽过氧化物酶比对照组高,血清前列腺素E 2、P物质、β-内啡肽水平比对照组低(P<0.05);观察组术后第1个月瘢痕美容评估与评级量表评分比对照组高(P<0.05);观察组并发症发生率与对照组比较,差异无统计学意义(P>0.05)。结论与传统S形切口操作相比,实施改良V形操作可有效减少术中出血量,减轻面部神经损伤程度,降低术后疼痛及氧化应激反应程度,改善手术瘢痕情况。 展开更多
关键词 腮腺良性肿瘤 疼痛介质 氧化应激 神经损伤 瘢痕 并发症
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