Regular monitoring of pulmonary congestion in car-diogenic pulmonary edema (CPE) patients is neces-sary for its adequate management via pharmaceuti-cal treatment. It is well known that the development of CPE is accomp...Regular monitoring of pulmonary congestion in car-diogenic pulmonary edema (CPE) patients is neces-sary for its adequate management via pharmaceuti-cal treatment. It is well known that the development of CPE is accompanied with an increase in hema-tocrit, plasma protein concentration and colloid os-motic pressure due to the decrease in the plasma volume. In the present study the mean left and right lung resistivity values taken pre- and post treatment with diuretics using a hybrid bio-impedance electri-cal impedance tomography system were correlate to the measured changes in hematocrit level. A marginal significant correlation was found between the abso-lute mean lung resistivity and hematocrit levels (Pearson’s correlation coefficient of R = 0.4, p-value = 0.057). When the change in the mean lung resistivity of a patient was plotted vs. the change in hematocrit readout, a significant linear correlation was found (R = 0.7, p-value = 0.02). These results support the validity of the resistivity measurements using bio-impedance system in monitoring changes of pulmonary edema in CPE patients.展开更多
文摘Regular monitoring of pulmonary congestion in car-diogenic pulmonary edema (CPE) patients is neces-sary for its adequate management via pharmaceuti-cal treatment. It is well known that the development of CPE is accompanied with an increase in hema-tocrit, plasma protein concentration and colloid os-motic pressure due to the decrease in the plasma volume. In the present study the mean left and right lung resistivity values taken pre- and post treatment with diuretics using a hybrid bio-impedance electri-cal impedance tomography system were correlate to the measured changes in hematocrit level. A marginal significant correlation was found between the abso-lute mean lung resistivity and hematocrit levels (Pearson’s correlation coefficient of R = 0.4, p-value = 0.057). When the change in the mean lung resistivity of a patient was plotted vs. the change in hematocrit readout, a significant linear correlation was found (R = 0.7, p-value = 0.02). These results support the validity of the resistivity measurements using bio-impedance system in monitoring changes of pulmonary edema in CPE patients.
文摘目的:探讨重症肺动脉高压患者终末期临床特点及救治策略。方法:回顾性分析2000至2004期间我院肺动脉高压死亡患者19例的临床表现及治疗经过。结果:12例患者末次住院诱因为肺部感染。19例患者肺动脉收缩压平均(100.6±20.2)mm Hg(1 mm Hg=0.133 Kpa),右心室内径与左心室内径之比(RV/LV)为1.12±0.52。死亡前诱发因素主要为大便用力(42.1%)和突然的体位改变(10.5%);死亡前呼吸频率及心率明显加快,超声心动图检查示右心室较入院时进一步扩大。分析患者直接死亡原因,10例为心源性休克(52.6%),6例为急性肺水肿(31.6%),2例为失血性休克(10.5%),1例为呼吸衰竭(5.2%)。结论:重症肺动脉高压尤其是心室内径之比RV/LV>1.0预后差,常在使心率加快、回心血量骤然减少等诱发因素下,启动急性肺水肿和心源性休克抢救,无效死亡。目前尚无明确有效的抢救措施。因此,应当积极预防和控制各项诱发因素,尝试不同给药途径合理应用血管活性药物进行救治。
