ANALYSIS OF MOTIF IN TCR Vβ HV4 SEQUENCES BINDING SUPERANTIGEN TSST-1

首先对４１种人和小鼠的Ｔ细胞受体β链可变基因编码肽段（Ｖβ）的氨基酸序列进行多序列对准，就Ｖβ之第四高变区（ＨＶ４）片段进行比较，分析与超抗原毒素休克综合征毒素－１（ＴＳＳＴ－１）结合的四种Ｖβ（小鼠Ｖβ３、Ｖβ１５、Ｖβ１７和人Ｖβ２）之ＨＶ４序列内是否存在特定的氨基酸残基排列模式。结果发现：小鼠Ｖβ３和Ｖβ１７的ＨＶ４具有特异的ＲＦＳＡＸＣＸＳＮＳ模式，而小鼠Ｖβ１５和人Ｖβ２的ＨＶ４则含独特的ＫＦＸＩＸＨ模式。提示：与ＴＳＳＴ－１结合的四种Ｖβ所对应的Ｔ细胞识别表位可能不止一个。

液晶电视 夏普LCD-37HV4

LCD—37HV4的TFT高精细液晶显示屏采用夏普独有的ASV技术,像素高达1366水平×768垂直(相当于50寸等离子电视的水平),上下左右170度大视角。新开发的QS(Quick Shoot)技术,清晰再现快速移动物体,无画面滞留现象。它的使用寿命长(背光灯寿命约为6万小时),是同等尺寸的等离子电视的三倍,耗电量不足等离子电视的三分之一,重量是等离子电视的一半。

超抗原TSST-1之靶TCRVβHV4序列的特征分析

首先对人和小鼠的TCRVβ的氨基酸序列进行多序列对准,就Vβ之HV4片段进行比较,分析与超抗原TSST-1结合的四种Vβ（小鼠Vβ3、Vβ15、Vβ17和人Vβ2）之HV4序列内是否存在特定的氨基酸残基排列主型。结果发现:小鼠Vβ3和Vβ17的HV4具有特异的RFSAXCXSNS主型,而小鼠Vβ15和人β2的HV4则含独特的KFXIXH主型。提示:与TSST-1结合的四种Vβ所对应的T细胞识别表位可能不止一个。

Production of Biodegradable Copolyesters and Terpolyesters of Polyhydroxyalkanoates by Alcaligenes latus DSM 1124

Copolyesters of 3 hydroxybutyrate and 4 hydroxybutyrate along with terpolyesters of 3 hydroxybutyrate, 3 hydroxyvalerate and 4 hydroxybutyrate were produced using Alcaligenes latus DSM 1124 in growth media with precursors of 1,4 butanediol or 1,4 butanediol and valerate. Monomer mass fraction w in the copolyesters varied from 63% to 78% 3 hydroxybutyrate and 1 5% to 6 5% 4 hydroxybutyrate (cell dry weight), depending on precursor supplied. w(monomer) in the terpolyesters varied from 55% to 69% 3 hydroxybutyrate, 0 5% to 3 4% 4 hydroxybutyrate and 3 4% to 16% 3 hydroxyvalerate.