Effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section

Objective:To discuss the effect of Hemabate combined with packing therapy on the systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section. Methods:70 patients with postpartum hemorrhage after placenta previa cesarean section who were treated in Chengdu Women & Children's Central Hospital between January 2014 and February 2017 were collected and then divided into the control group (n=35) who received uterine packing therapy and the observation group (n=35) who received Hemabate combined with packing therapy according to random number table. Serum levels of oxidative stress indexes and stress hormones immediately after operation and 24 h after operation were compared between two groups of patients.Results: Immediately after operation and 24 h after operation, serum oxidative stress indexes ROS and MDA levels of observation group were significantly lower than those of control group while SOD, GSH-px and CAT levels were significantly higher than those of control group, and serum stress hormones NE, E and Cor levels were significantly lower than those of control group.Conclusion: Hemabate combined with packing therapy can effectively reduce systemic stress response in patients with postpartum hemorrhage after placenta previa cesarean section, is a more ideal way of the bleeding.

米索前列醇与卡前列素氨丁三醇治疗产后出血的临床疗效研究

目的探究米索前列醇与卡前列素氨丁三醇(欣母沛)治疗产后出血的价值。方法选取产后出血产妇80例,分为两组,分别给予米索前列醇以及欣母沛治疗,对比疗效。结果实验组产后出血产妇疗效、出血量、不良反应发生率等均与对照组产后出血产妇相比,差异具有统计学意义(P<0.05)。结论欣母沛在产后出血中应用,疗效优于米索前列醇,可促进产妇出血量的减少,且安全性较高。