Objective： To assess the efficacy and safety of acupuncture for hyperlipidemia in adults. Methods： We searched electronic databases, including PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, CB...Objective： To assess the efficacy and safety of acupuncture for hyperlipidemia in adults. Methods： We searched electronic databases, including PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, CBM, CNKI, and VIP. All included studies were assessed in terms of quality and risk bias. The Review Manager 5.3.3 software was used for the data analyses, and the GRADE profiler software was applied to classify the systematic review results. Results： Seventeen studies were identified （n = 1,408）. Acupuncture （electro-acupuncture or magnetic needle） was equally as effective as sham treatment （needle acupuncture） （relative risk [RR], 0.95; 95% confidence interval [CI], 0.72-1.24）. Acupuncture （needle acupuncture, electro-acupuncture, moxibustion, and acupoint catgut embedding） was as effective as statin therapy （RR 0.10; 95%CI, 0.97-1.24）. Acupuncture was as effective as Chinese herbal preparations （electro-acupuncture and auricular acupoint） （RR, 0.97; 95%CI, 0.89-1.06）. However, insufficient evidence was available to demonstrate whether acupressure was effective compared with acupuncture plus other treatments （RR, 1.04; 95%CI, 0.87-1.25）. Conclusion： Acupuncture may improve hyperlipidemia levels. However, additional large, properly randomized, placebo-controlled, double-blind studies are required.展开更多
Objective:To access the pancreatic lipase,cholesterol esterase and cholesterol micellization inhibitory activities of Sri Lankan low grown orthodox Orange Pekoe grade black tea made from uppermost tender leaves and un...Objective:To access the pancreatic lipase,cholesterol esterase and cholesterol micellization inhibitory activities of Sri Lankan low grown orthodox Orange Pekoe grade black tea made from uppermost tender leaves and unopened buds of Camellia sinensis L.Methods:Black tea brew(BTB)was made according to International Organization for Standardization 3103 specifications and concentrations of BTB tested were 37.5,75.0,150.0,300.0 and 600.0μg/mL for antilipase and anti-cholesterol esterase assays and 0.25,0.50 and 1.00μg/mL for cholesterol micellization inhibitory assay.Results:The results showed that BTB of Sri Lankan low grown orthodox Orange Pekoe grade black tea has marked and dose-dependent(r^(2)=0.95)cholesterol micellization inhibitory activity in vitro comparable to epigallocatechin gallate,the reference drug used.In contrast,BTB had only mild but dose-dependent(r^(2)=0.94)inhibitory activity against pancreatic lipase and weak inhibitory effect(up to 13.17%)on pancreatic cholesterol esterase.Conclusions:It is concluded that consumption of BTB of Sri Lankan low grown orthodox Orange Pekoe grade tea as a beverage may be a useful strategy in the management of hyperlipidaemia.展开更多
文摘Objective： To assess the efficacy and safety of acupuncture for hyperlipidemia in adults. Methods： We searched electronic databases, including PubMed, the Cochrane Central Register of Controlled Trials, EMBASE, CBM, CNKI, and VIP. All included studies were assessed in terms of quality and risk bias. The Review Manager 5.3.3 software was used for the data analyses, and the GRADE profiler software was applied to classify the systematic review results. Results： Seventeen studies were identified （n = 1,408）. Acupuncture （electro-acupuncture or magnetic needle） was equally as effective as sham treatment （needle acupuncture） （relative risk [RR], 0.95; 95% confidence interval [CI], 0.72-1.24）. Acupuncture （needle acupuncture, electro-acupuncture, moxibustion, and acupoint catgut embedding） was as effective as statin therapy （RR 0.10; 95%CI, 0.97-1.24）. Acupuncture was as effective as Chinese herbal preparations （electro-acupuncture and auricular acupoint） （RR, 0.97; 95%CI, 0.89-1.06）. However, insufficient evidence was available to demonstrate whether acupressure was effective compared with acupuncture plus other treatments （RR, 1.04; 95%CI, 0.87-1.25）. Conclusion： Acupuncture may improve hyperlipidemia levels. However, additional large, properly randomized, placebo-controlled, double-blind studies are required.
基金Supported by National Science Foundation of Sri Lanka(Grant No.NSF/Fellow/2011/01).
文摘Objective:To access the pancreatic lipase,cholesterol esterase and cholesterol micellization inhibitory activities of Sri Lankan low grown orthodox Orange Pekoe grade black tea made from uppermost tender leaves and unopened buds of Camellia sinensis L.Methods:Black tea brew(BTB)was made according to International Organization for Standardization 3103 specifications and concentrations of BTB tested were 37.5,75.0,150.0,300.0 and 600.0μg/mL for antilipase and anti-cholesterol esterase assays and 0.25,0.50 and 1.00μg/mL for cholesterol micellization inhibitory assay.Results:The results showed that BTB of Sri Lankan low grown orthodox Orange Pekoe grade black tea has marked and dose-dependent(r^(2)=0.95)cholesterol micellization inhibitory activity in vitro comparable to epigallocatechin gallate,the reference drug used.In contrast,BTB had only mild but dose-dependent(r^(2)=0.94)inhibitory activity against pancreatic lipase and weak inhibitory effect(up to 13.17%)on pancreatic cholesterol esterase.Conclusions:It is concluded that consumption of BTB of Sri Lankan low grown orthodox Orange Pekoe grade tea as a beverage may be a useful strategy in the management of hyperlipidaemia.
