The phenomenon of marital dissolution in later life,also referred to as“gray divorce”,is described on the rise in contemporary Western societies.This article contributes to the study of marriage breakdown in older a...The phenomenon of marital dissolution in later life,also referred to as“gray divorce”,is described on the rise in contemporary Western societies.This article contributes to the study of marriage breakdown in older age,with a specific focus on Italian society.First,the temporal trends of this phenomenon are reconstructed using official statistics.The data reveal that,although still relatively rare,the dissolution of marriage in later life is expanding in Italy.The analysis of the period from 1974 to 2015 indicates a rise in the average age at separation,a higher percentage of spouses over 50 years on the total number of couples obtaining legal separation,and an increase in the proportion of Italian spouses separating after many years of marriage.Furthermore,data from the national survey“Family and Social Subjects”,conducted in 2016 by the Italian National Institute of Statistics,are utilized to explore the relationship between specific traits of those who separated and their tendency to dissolve marriages before or after the age of 50.The data suggest that individuals with characteristics such as lower educational attainment,residence in the South and Islands,and adherence to more traditional family models are more likely to experience separation in later life.展开更多
Chinese ambassador to Italy Jia Guide believes that the future of China-Italy relations is promising and that the two countries will further strengthen cooperation in jointly building a road to prosperity.
AIM: To investigate the seroprevalence of Helicobacter pylori (Hpylori) infection and its more virulent strains as well as the correlation with the histologic features among patients who had undergone surgery for g...AIM: To investigate the seroprevalence of Helicobacter pylori (Hpylori) infection and its more virulent strains as well as the correlation with the histologic features among patients who had undergone surgery for gastric cancer (GC). METHODS: Samples from 317 (184 males, 133 females, mean age 69±3.4 years) consecutive patientswho had undergone surgery for gastric non-cardia adenocarcinoma were included in the study. Five hundred and fifty-five (294 males, 261 females, mean age 57.3±4.1 years) patients consecutively admitted to the Emergency Care Unit served as control. Histological examination of tumor, lymph nodes and other tissues obtained at the time of surgery represented the diagnostic "gold standard': An enzyme immunosorbent assay was used to detect serum anti-H pylori (IgG) antibodies and Western blotting technique was utilized to search for anti-CagA protein (IgG). RESULTS: Two hundred and sixty-one of three hundred and seventeen (82.3%) GC patients and 314/555 (56.5%) controls were seropositive for anti-H pylori (P〈0.0001; OR, 3.58; 95%CI, 2.53-5.07). Out of the 317 cases, 267 (84.2%) were seropositive for anti-CagA antibody vs 100 out of 555 (18%) controls (P〈0.0001; OR, 24.30; 95%CI, 16.5-35.9). There was no difference between the frequency of H pylori in intestinal type carcinoma (76.2%) and diffuse type cancer (78.8%). Intestinal metaplasia (IM) was more frequent but not significant in the intestinal type cancer (83.4% vs 75.2% in diffuse type and 72.5% in mixed type). Among the patients examined for IM, 39.8% had IM type Ⅰ, 8.3% type Ⅱ and 51.9% type Ⅲ (type IU vs others, P = 0.4). CONCLUSION: This study confirms a high seroprevalence of H pylori infection in patients suffering from gastric adenocarcinoma and provides further evidence that searching for CagA status over H pylori infection might confer additional benefit in identifying populations at greater risk for this tumor.展开更多
andslide risk analysis is one of the primary studies providing essential instructions to the subsequent risk management process. The quantification of tangible and intangible potential losses is a critical step becau...andslide risk analysis is one of the primary studies providing essential instructions to the subsequent risk management process. The quantification of tangible and intangible potential losses is a critical step because it provides essential data upon which judgments can be made and policy can be formulated. This study aims at quantifying direct economic losses from debris flows at a medium scale in the study area in Italian Central Alps. Available hazard maps were the main inputs of this study. These maps were overlaid with information concerning elements at risk and their economic value. Then, a combination of both market and construction values was used to obtain estimates of future economic losses. As a result, two direct economic risk maps were prepared together with risk curves, useful to summarize expected monetary damage against the respective hazard probability. Afterwards, a qualitative risk map derived using a risk matrix officially provided by the set of laws issued by the regional government, was prepared. The results delimit areas of high economic as well as strategic importance which might be affected by debris flows in the future. Aside from limitations and inaccuracies inherently included in risk analysis process, identification of high risk areas allows local authorities to focus their attention on the “hot-spots”, where important consequences may arise and local (large) scale analysis needs to be performed with more precise cost-effectiveness ratio. The risk maps can be also used by the local authorities to increase population’s adaptive capacity in the disaster prevention process.展开更多
We estimate Love wave empirical Green's functions from cross-correlations of ambient seismic noise to study the crust and uppermost mantle structure in Italy. Transverse-component ambient noise data from October 2005...We estimate Love wave empirical Green's functions from cross-correlations of ambient seismic noise to study the crust and uppermost mantle structure in Italy. Transverse-component ambient noise data from October 2005 through March 2007 recorded at 114 seismic stations from the Istituto Nazionale di Geofisica e Vulcanologia (INGV) national broadband network, the Mediterranean Very Broadband Seismographic Network (MedNet) and the Austrian Central Institute for Meteorology and Geodynamics (ZAMG) yield more than 2 000 Love wave group velocity measurements using the multiple-filter analysis technique. In the short period band (5-20 s), the cross-correlations show clearly one-sided asymmetric feature due to non-tmiform noise distribution and high local activities, and in the long period band (〉20 s) this feature becomes weak owing to more diffusive noise distribution. Based on these measurements, Love wave group velocity dispersion maps in the 8-34 s period band are constructed, then the SH wave velocity structures from the Love wave dispersions are inverted. The final results obtained from Love wave data are overall in good agreement with those from Rayleigh waves. Both Love and Rayleigh wave inversions all reveal that the Po plain basin is resolved with low velocity at shallow depth, and the Tyrrhenian sea is characterized with higher velocity below 8 km due to its thin oceanic crust.展开更多
The Erectile Dysfunction Observational Study (EDOS) is a 6-months observational prospective multicentric study enrolling men with erectile dysfunction (ED) who asked, to be started on a treatment or to change a pr...The Erectile Dysfunction Observational Study (EDOS) is a 6-months observational prospective multicentric study enrolling men with erectile dysfunction (ED) who asked, to be started on a treatment or to change a previous treatment. Aims of the study were to analyse the pattern of treatment and compare the efficacy of treatments used. Patients were enrolled during a normal hospital visit and were prescribed a treatment for ED. They were asked at baseline and after 3 and 6 months, to answer a set of questions from the International Index of Erectile Function, Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) and Short Form of the Psychological and Interpersonal Relationships Scale questionnaires (SF-PAIRS). Clinicians were free to prescribe any therapy for ED available in the market, and to change therapy at any time during the study. Out of 1 338 patients, available for analysis at 6 months, 624 (47%) changed their treatment during the study and 714 (53%) continued with the drug prescribed at baseline. Patients assuming tadalafil had a significantly higher probability of maintaining the same treatment compared to sildenafil or vardenafil. There was no clinically significant difference in terms of efficacy, patient satisfaction, self-confidence and spontaneity between the different inhibitors of PDE5. The ‘time concerns' domain score of SF-PAIRS, was statistically better in patients assuming tadalafil. In conclusion sildenafil, vardenafil and tadalafil show similar efficacy in the clinical practice. However, patients receiving tadalafil display a lower risk to discontinue or change the treatment.展开更多
Stochastic modelling of hydrological time series with insufficient length and data gaps is a serious challenge since these problems significantly affect the reliability of statistical models predicting and forecasting...Stochastic modelling of hydrological time series with insufficient length and data gaps is a serious challenge since these problems significantly affect the reliability of statistical models predicting and forecasting skills.In this paper,we proposed a method for searching the seasonal autoregressive integrated moving average(SARIMA)model parameters to predict the behavior of groundwater time series affected by the issues mentioned.Based on the analysis of statistical indices,8 stations among 44 available within the Campania region(Italy)have been selected as the highest quality measurements.Different SARIMA models,with different autoregressive,moving average and differentiation orders had been used.By reviewing the criteria used to determine the consistency and goodness-of-fit of the model,it is revealed that the model with specific combination of parameters,SARIMA(0,1,3)(0,1,2)_(12),has a high R^(2) value,larger than 92%,for each of the 8 selected stations.The same model has also good performances for what concern the forecasting skills,with an average NSE of about 96%.Therefore,this study has the potential to provide a new horizon for the simulation and reconstruction of groundwater time series within the investigated area.展开更多
This research deals with an evaluation of the sink of greenhouse gas CO2 in a eutrophic area of the Venetian lagoon where fish is farmed ("Valle da pesca"). Following CDM UNFCCC (Clean Development Mechanism Unite...This research deals with an evaluation of the sink of greenhouse gas CO2 in a eutrophic area of the Venetian lagoon where fish is farmed ("Valle da pesca"). Following CDM UNFCCC (Clean Development Mechanism United Nations Framework Convention on Climate Change) criteria, this can be considered relevant to the international standard for the voluntary evaluation of carbon credits on the basis of Annex a of Kyoto Protocol. To identify the "Valle da pesca" brackish lagoon properties regulating the carbon dioxide (CO2), a survey has been performed during three seasons in one year and in four different locations. These places are located in the Italian Venetian Lagoon and in the Grado Lagoon in North Italy, Europe. To identify the CO2 sink capacity, a special index is calculated. The CO2 concentrations and sink are regulated by the balance of autotrophic and heterotrophic activities, and the sediment anoxic denitrification and macro algae are crucial tank of CO2 in the valley shallow waters. The ponds potential-CO2 yield of 80-124 kg/m2 per year and the value are related and proportional to the correct human environmental control (water flux control).展开更多
Outward Foreign Direct Investment (OFDI) from emerging economies has begun to increase significantly and has been growing at a faster pace than Foreign Direct Investment (FDI) from the developed world. This resear...Outward Foreign Direct Investment (OFDI) from emerging economies has begun to increase significantly and has been growing at a faster pace than Foreign Direct Investment (FDI) from the developed world. This research seeks to assess the impact of Chinese acquisitions and their implications for the "Made in Italy" luxury sector and its firms. This paper presents a cross-case analysis of two Chinese acquisitions in order to provide some in-depth insights into the influences and the motives driving Chinese firms to invest in the luxury Made in Italy sector, the patterns and modes of the Chinese acquisitions as well as the competitive strategies and the distinctive challenges that both investors and acquired firms have to face. From the findings, it emerges that both the investor and the acquired firm need to overcome several key challenges to be mutual benefits from the acquisition.展开更多
Climate conditions play a crucial role in the survival of mountain communities, whose survival already critically depends on socioeconomic factors. In the case of montane areas that are prone to natural haz-ards, such...Climate conditions play a crucial role in the survival of mountain communities, whose survival already critically depends on socioeconomic factors. In the case of montane areas that are prone to natural haz-ards, such as alpine slope failure and debris flows, climatic factors exert a major influence that should be considered when creating appropriate sustainable scenarios. In fact, it has been shown that climate change alters the availability of ecosystem services (ES), thus increasing the risks of declining soil fertility and reduced water availability, as well as the loss of grassland, potential shifts in regulatory services (e.g., protection from natural hazards), and cultural services. This study offers a preliminary discussion on a case study of a region in the Italian Alps that is experiencing increased extreme precipitation and erosion, and where an isolated and historically resilient community directly depends on a natural resource econ- omy. Preliminary results show that economic factors have influenced past population trends of the Novalesa community in the Piemonte Region in northwest Italy. However, the increasing number of rock fall and debris flow events, which are triggered by meteo-climatic factors, may further influence the livelihood and weflbeing of this community, and of other similar communities around the world, Therefore, environmental monitoring and data analysis will be important means of detecting trends in landscape and climate change and choosing appropriate planning options. Such analysis, in turn, would ensure the survival of about 10% of the global population, and would also represent a possibility for future economic development in critical areas prone to poverty conditions.展开更多
In order to assess the seismic hazard in an area with high seismogenic potential as the Messina Straits is, we employed the Cornell’s probabilistic approach, implemented by Bender and Perkins in the SEISRISKⅢcode,wh...In order to assess the seismic hazard in an area with high seismogenic potential as the Messina Straits is, we employed the Cornell’s probabilistic approach, implemented by Bender and Perkins in the SEISRISKⅢcode,which allows calculating the expected ground motion.We considered all the earthquakes with magnitude M_s】4.0 reported in the CPTI04 catalogue and located in the seismogenic zones of Southern Italy(ZS9),which are able to展开更多
The Calabria-Peloritani Arc is one of the most seismically active regions of Southern Italy.The most damaging event(Ⅰ0=ⅪMSK)occurred on December 28th,1908 in the Messina Straits area.This event,which caused at least...The Calabria-Peloritani Arc is one of the most seismically active regions of Southern Italy.The most damaging event(Ⅰ0=ⅪMSK)occurred on December 28th,1908 in the Messina Straits area.This event,which caused at least 85000 casualties and widespread damage,has been identified as the greatest European seismic disaster of the 20th century.展开更多
Debris flows play an important role among natural hazards in mountainous areas of Italy.This paper provides an overview on the recent research on debris flows conducted in italy, taking into account both hydraulic an...Debris flows play an important role among natural hazards in mountainous areas of Italy.This paper provides an overview on the recent research on debris flows conducted in italy, taking into account both hydraulic and geomorphological studies. Moreover,t展开更多
AIM:To investigate the role of protein tyrosin phosphatase 22(PTPN22),maternal age at conception and sex on susceptibility and age at onset of type 1 diabetes(T1D)in Continental Italy and Sardinian populations.METHODS...AIM:To investigate the role of protein tyrosin phosphatase 22(PTPN22),maternal age at conception and sex on susceptibility and age at onset of type 1 diabetes(T1D)in Continental Italy and Sardinian populations.METHODS:Three hundred seventy six subjects admitted consecutively to the hospital for T1D and 1032healthy subjects as controls were studied in Continental Italy and 284 subjects admitted consecutively to the hospital for T1D and 5460 healthy newborns were studied in Sardinia.PTPN22 genotype was determined by DNA analysis.Maternal age at conception and age at onset of disease were obtained from clinical records.χ2 test of independence,student t test for differences between means and odds ratio analysis were carried out by SPSS programs.Three way contingency table analysis was carried out according to Sokal and Rohlf.RESULTS:The pattern of association between PTPN22and T1D is similar in Continental Italy and Sardinia:the proportion of*T allele carriers is 13.6%in T1D vs6.7%in controls in Continental Italy while in Sardinia is 7.3%in T1D vs 4.4%in controls.The association between T1D and maternal age at conception is much stronger in Sardinia than in Italy:the proportion of newborn from mother aging more than 32 years is89.3%in T1D vs 32.7%in consecutive newborn in Sardinia(P<10-6)while in Continental Italy is 32.2%in T1D vs 19.1%in consecutive newborns(P=0.005).This points to an important role of ethnicity.A slight prevalence of T1D males on T1D females is observed both in Continental Italy and Sardinia.PTPN22 genotype does not exert significant effect on the age at onset neither in Continental Italy nor and Sardinia.Maternal age does not influence significantly age at onset in Italy(8.2 years in T1D infants from mothers aging32 years or less vs 7.89 years in T1D infants from mothers aging more than 32 years:P=0.824)while in Sardinia a border line effect is observed(5.75 years in T1D infants from mothers aging 32 years or less vs7.54 years in T1D infants from mothers aging more than 32 years:P=0.062).No effect of sex on age at onset is observed in Continental Italy while in Sardinia female show a lower age at onset of T1D as compared to males(8.07 years in males vs 6.3 years in females:P=0.002).CONCLUSION:The present data confirm the importance of ethnicity on susceptibility and on the age at onset of T1D.展开更多
Fagonia cretica L. is an important component of Mediterranean dry grasslands and a rare and isolated species of Italian flora. In this study, an assessment is presented on the distribution, habitat, and conservation s...Fagonia cretica L. is an important component of Mediterranean dry grasslands and a rare and isolated species of Italian flora. In this study, an assessment is presented on the distribution, habitat, and conservation status of F. cretica in Italy. The results of field investigation and herbarium analysis show that this species grows in a small area within the southern Calabria region characterized by a warmest and driest Mediterranean climate on the Italian peninsula. F. cretica is a semi-desert plant species growing in Italy in only one peripheral and isolated population at the northern limit of its distribution. Plant community analysis, using the phytosociological method, shows that F. cretica grows in wintergreen perennial dry grasslands dominated by Lygeum {partum and Hyparrhenia hirta. F. crelica plant communities are located in thermo-xeric habits such as south-, southeast- and east-facing slopes on clays and sandy clays in southern Calabria. The population of F. cretica is fragmented in six neighbouring localities, with two of which belonging to a Site of Community Importance (SC1). The conservation status of F. cretica population is not very good, and is defined as "Critically Endangered" in accordance with IUCN criteria. There are many threats affecting the F. crelica population in ltaly, primarily the changes in land uses due to urban expansion and reforestation with exotic plants. The southern end of the Italian peninsula hosts other plants from thermo-xeric habits that do not adapt to the current local climate. This territory can be considered as a microrefugia for plants currently distributed in the arid territory of the southern Mediterranean. These results contribute to the discussion of some conservation measures, and the possibility of establishing a micro-reserve. For all these reasons, we propose to include F. cretica in the lists of protected plant species at regional (Calabria) and country (Italy) scales in Italy.展开更多
The conceptual hydrogeological model of the Viterbo thermal area in central Italy and the yield of the groundwater sys- tem have been examined. This area is of great geothermal interest. Through new investigations, th...The conceptual hydrogeological model of the Viterbo thermal area in central Italy and the yield of the groundwater sys- tem have been examined. This area is of great geothermal interest. Through new investigations, three overlapping aquifers have been found. This study examines in detail the two shallower aquifers, characterized by different hydraulic and chemical characteristics. The first aquifer is related to the regional groundwater flow of the Cimino-Vico volcanic system and is generally characterized by cold, fresh waters used for irrigation and drinking water supply. The second aquifer, i.e. the thermal aquifer, supply thermal spas and public pools;it is present where the local hydrostratigraphic, structural and geothermal conditions permit a relatively active flow of higher salinity thermal waters (40?C - 62?C). These two aquifers interact vertically and laterally, giving rise to mixed waters circulating in the first aquifer. The first aquifer is recharged by direct infiltration and inflow from regional groundwater, as well as inflow from the second aquifer. The yield of the thermal aquifer is at least 170 L/s, discharging into thermal springs and wells, besides feeding the shallow aquifer vertically and laterally. Even if a future development of the second aquifer is potentially achievable on a global scale, the exploitation of the thermal waters is strictly dependent on the specific local hydrogeological equilibrium between the overlapping aquifers, different from place to place. The case study highlights that, in the volcanic hydrogeological environment, one of the most stringent constraints in determining the correct usage of a resource is the variable level of interaction of groundwater with different qualities.展开更多
A three-phase pesticide transport model is used to verify by numerical simulation, the influence of different parameters on infiltration through soil and/or surface runoff processes. Simulations are performed for a ty...A three-phase pesticide transport model is used to verify by numerical simulation, the influence of different parameters on infiltration through soil and/or surface runoff processes. Simulations are performed for a typical sandy loam potato field of Italy’s Fucino Plain, to explain the occurrence of measured concentrations of pesticides (mainly Linuron) in both surface waters and groundwater. Simulations take into account agricultural practices, climatic conditions, and soil characteristics. Results focus on the role of rainfall events and irrigation, of related infiltration amount and distribution, and of root zone thickness in influencing pesticide fate and its possible concentration increase through the years. Modeling results positively fit with the background knowledge of the Plain hydrology, showing the prevalence of surface transport and a scarce possibility for pesticides to reach groundwater in an average rainfall/irrigation scenario. Meanwhile, specific water management strategies are suggested to limit the occurrence of local groundwater pollution, related to high aquifer vulnerability zones, controlling inappropriate irrigation and pesticide application.展开更多
Organized by Consiglio Nazional delle Ricerche (CNR), Gruppo Nedonale diIdraulice(GNI) with the support of the Ministry of Public Works and under the auspices of theCoastal Engineering Research Council(CERC) of the Am...Organized by Consiglio Nazional delle Ricerche (CNR), Gruppo Nedonale diIdraulice(GNI) with the support of the Ministry of Public Works and under the auspices of theCoastal Engineering Research Council(CERC) of the American Society of CivilEngineering(ASCE), and co-sponsored by the international Association for Hydraulic of Navi-gation Congress(PIANC) and by the Associazione di Ingegneria Offshore e Marina(AIOM).Aim展开更多
This paper presents the results of the investigations, driven by different techniques, including environmental tracers and geophysical methods, in the aim of better understand the causes of the current salt-water intr...This paper presents the results of the investigations, driven by different techniques, including environmental tracers and geophysical methods, in the aim of better understand the causes of the current salt-water intrusion in the Pontina Plain, in the south of the Lazio Region (Italy). In the last 50 years many investigation campaigns have been carried out to evaluate the evolution of salt-water intrusion. This is an area with a strong man-made residential and tourist impact and, in the some cases, it is characterized by intensive agricultural practices. Therefore, it can be affected not only by salt-water intrusion, but by the salinization of its groundwater also due to other factors. All these factors have led the Pontina Plain to a groundwater situation which makes the groundwater resource management and the planning of their future exploitation very difficult.展开更多
The paper proposes a study for the delineation of protection zones in the main discharge area of the Gran Sasso aquifer (Central Italy). At this aim, starting from a detailed geological and hydrogeological reconstruct...The paper proposes a study for the delineation of protection zones in the main discharge area of the Gran Sasso aquifer (Central Italy). At this aim, starting from a detailed geological and hydrogeological reconstruction, the study was divided into the following phases: 1) development of a conceptual model of water flow in the study area;2) creation of a 3D numerical model in order to simulate the groundwater flow in saturated conditions, both at the basin and at fine-scale;3) flow path analysis through deterministic and stochastic approaches;4) assessment of the aquifer vulnerability based on a geomorphological analysis of the catchment area. Conceptual and numerical models were then used to delineate protection zones for wells and springs with chronological criterion and geomorphological-structural criterion (based on the EPIK method). The results show that with a chronological approach protection zones are located along the main flow directions, corresponding to the areas surrounding wells and springs with high hydraulic conductivity values (faults and thrusts) within the satured zone. On the contrary, the geomorphological method has found some important protection zones also quite far from wells and springs, in areas characterized by quick infiltration processes. The protection zones delineated with the stochastic method were finally intersected by the vulnerability map obtained with the EPIK method, to take into account both filtration and infiltration processes. The results show the local vulnerability of the groundwater to the pollution, with protection zones extending 1 to 5 km towards northeast from springs and wells.展开更多
文摘The phenomenon of marital dissolution in later life,also referred to as“gray divorce”,is described on the rise in contemporary Western societies.This article contributes to the study of marriage breakdown in older age,with a specific focus on Italian society.First,the temporal trends of this phenomenon are reconstructed using official statistics.The data reveal that,although still relatively rare,the dissolution of marriage in later life is expanding in Italy.The analysis of the period from 1974 to 2015 indicates a rise in the average age at separation,a higher percentage of spouses over 50 years on the total number of couples obtaining legal separation,and an increase in the proportion of Italian spouses separating after many years of marriage.Furthermore,data from the national survey“Family and Social Subjects”,conducted in 2016 by the Italian National Institute of Statistics,are utilized to explore the relationship between specific traits of those who separated and their tendency to dissolve marriages before or after the age of 50.The data suggest that individuals with characteristics such as lower educational attainment,residence in the South and Islands,and adherence to more traditional family models are more likely to experience separation in later life.
文摘Chinese ambassador to Italy Jia Guide believes that the future of China-Italy relations is promising and that the two countries will further strengthen cooperation in jointly building a road to prosperity.
基金Supported by the grants from Regione Piemonte, Ministry of Instruction,University and Research, University of Torino, AIRC,StolaAutoSpA
文摘AIM: To investigate the seroprevalence of Helicobacter pylori (Hpylori) infection and its more virulent strains as well as the correlation with the histologic features among patients who had undergone surgery for gastric cancer (GC). METHODS: Samples from 317 (184 males, 133 females, mean age 69±3.4 years) consecutive patientswho had undergone surgery for gastric non-cardia adenocarcinoma were included in the study. Five hundred and fifty-five (294 males, 261 females, mean age 57.3±4.1 years) patients consecutively admitted to the Emergency Care Unit served as control. Histological examination of tumor, lymph nodes and other tissues obtained at the time of surgery represented the diagnostic "gold standard': An enzyme immunosorbent assay was used to detect serum anti-H pylori (IgG) antibodies and Western blotting technique was utilized to search for anti-CagA protein (IgG). RESULTS: Two hundred and sixty-one of three hundred and seventeen (82.3%) GC patients and 314/555 (56.5%) controls were seropositive for anti-H pylori (P〈0.0001; OR, 3.58; 95%CI, 2.53-5.07). Out of the 317 cases, 267 (84.2%) were seropositive for anti-CagA antibody vs 100 out of 555 (18%) controls (P〈0.0001; OR, 24.30; 95%CI, 16.5-35.9). There was no difference between the frequency of H pylori in intestinal type carcinoma (76.2%) and diffuse type cancer (78.8%). Intestinal metaplasia (IM) was more frequent but not significant in the intestinal type cancer (83.4% vs 75.2% in diffuse type and 72.5% in mixed type). Among the patients examined for IM, 39.8% had IM type Ⅰ, 8.3% type Ⅱ and 51.9% type Ⅲ (type IU vs others, P = 0.4). CONCLUSION: This study confirms a high seroprevalence of H pylori infection in patients suffering from gastric adenocarcinoma and provides further evidence that searching for CagA status over H pylori infection might confer additional benefit in identifying populations at greater risk for this tumor.
基金supported by the Marie Curie Research and Training Network "Mountain Risks" funded by the European Commission (2007–2010, Contract MCRTN-35098).
文摘andslide risk analysis is one of the primary studies providing essential instructions to the subsequent risk management process. The quantification of tangible and intangible potential losses is a critical step because it provides essential data upon which judgments can be made and policy can be formulated. This study aims at quantifying direct economic losses from debris flows at a medium scale in the study area in Italian Central Alps. Available hazard maps were the main inputs of this study. These maps were overlaid with information concerning elements at risk and their economic value. Then, a combination of both market and construction values was used to obtain estimates of future economic losses. As a result, two direct economic risk maps were prepared together with risk curves, useful to summarize expected monetary damage against the respective hazard probability. Afterwards, a qualitative risk map derived using a risk matrix officially provided by the set of laws issued by the regional government, was prepared. The results delimit areas of high economic as well as strategic importance which might be affected by debris flows in the future. Aside from limitations and inaccuracies inherently included in risk analysis process, identification of high risk areas allows local authorities to focus their attention on the “hot-spots”, where important consequences may arise and local (large) scale analysis needs to be performed with more precise cost-effectiveness ratio. The risk maps can be also used by the local authorities to increase population’s adaptive capacity in the disaster prevention process.
基金supported in part by the 2004-2006 National Civil Defense Project of Italy (DPC)-S4, 2007-2009 DPC-S3the Fundamental Research Funds for the Central Universities of China under grant No. 2010ZD06
文摘We estimate Love wave empirical Green's functions from cross-correlations of ambient seismic noise to study the crust and uppermost mantle structure in Italy. Transverse-component ambient noise data from October 2005 through March 2007 recorded at 114 seismic stations from the Istituto Nazionale di Geofisica e Vulcanologia (INGV) national broadband network, the Mediterranean Very Broadband Seismographic Network (MedNet) and the Austrian Central Institute for Meteorology and Geodynamics (ZAMG) yield more than 2 000 Love wave group velocity measurements using the multiple-filter analysis technique. In the short period band (5-20 s), the cross-correlations show clearly one-sided asymmetric feature due to non-tmiform noise distribution and high local activities, and in the long period band (〉20 s) this feature becomes weak owing to more diffusive noise distribution. Based on these measurements, Love wave group velocity dispersion maps in the 8-34 s period band are constructed, then the SH wave velocity structures from the Love wave dispersions are inverted. The final results obtained from Love wave data are overall in good agreement with those from Rayleigh waves. Both Love and Rayleigh wave inversions all reveal that the Po plain basin is resolved with low velocity at shallow depth, and the Tyrrhenian sea is characterized with higher velocity below 8 km due to its thin oceanic crust.
文摘The Erectile Dysfunction Observational Study (EDOS) is a 6-months observational prospective multicentric study enrolling men with erectile dysfunction (ED) who asked, to be started on a treatment or to change a previous treatment. Aims of the study were to analyse the pattern of treatment and compare the efficacy of treatments used. Patients were enrolled during a normal hospital visit and were prescribed a treatment for ED. They were asked at baseline and after 3 and 6 months, to answer a set of questions from the International Index of Erectile Function, Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) and Short Form of the Psychological and Interpersonal Relationships Scale questionnaires (SF-PAIRS). Clinicians were free to prescribe any therapy for ED available in the market, and to change therapy at any time during the study. Out of 1 338 patients, available for analysis at 6 months, 624 (47%) changed their treatment during the study and 714 (53%) continued with the drug prescribed at baseline. Patients assuming tadalafil had a significantly higher probability of maintaining the same treatment compared to sildenafil or vardenafil. There was no clinically significant difference in terms of efficacy, patient satisfaction, self-confidence and spontaneity between the different inhibitors of PDE5. The ‘time concerns' domain score of SF-PAIRS, was statistically better in patients assuming tadalafil. In conclusion sildenafil, vardenafil and tadalafil show similar efficacy in the clinical practice. However, patients receiving tadalafil display a lower risk to discontinue or change the treatment.
文摘Stochastic modelling of hydrological time series with insufficient length and data gaps is a serious challenge since these problems significantly affect the reliability of statistical models predicting and forecasting skills.In this paper,we proposed a method for searching the seasonal autoregressive integrated moving average(SARIMA)model parameters to predict the behavior of groundwater time series affected by the issues mentioned.Based on the analysis of statistical indices,8 stations among 44 available within the Campania region(Italy)have been selected as the highest quality measurements.Different SARIMA models,with different autoregressive,moving average and differentiation orders had been used.By reviewing the criteria used to determine the consistency and goodness-of-fit of the model,it is revealed that the model with specific combination of parameters,SARIMA(0,1,3)(0,1,2)_(12),has a high R^(2) value,larger than 92%,for each of the 8 selected stations.The same model has also good performances for what concern the forecasting skills,with an average NSE of about 96%.Therefore,this study has the potential to provide a new horizon for the simulation and reconstruction of groundwater time series within the investigated area.
文摘This research deals with an evaluation of the sink of greenhouse gas CO2 in a eutrophic area of the Venetian lagoon where fish is farmed ("Valle da pesca"). Following CDM UNFCCC (Clean Development Mechanism United Nations Framework Convention on Climate Change) criteria, this can be considered relevant to the international standard for the voluntary evaluation of carbon credits on the basis of Annex a of Kyoto Protocol. To identify the "Valle da pesca" brackish lagoon properties regulating the carbon dioxide (CO2), a survey has been performed during three seasons in one year and in four different locations. These places are located in the Italian Venetian Lagoon and in the Grado Lagoon in North Italy, Europe. To identify the CO2 sink capacity, a special index is calculated. The CO2 concentrations and sink are regulated by the balance of autotrophic and heterotrophic activities, and the sediment anoxic denitrification and macro algae are crucial tank of CO2 in the valley shallow waters. The ponds potential-CO2 yield of 80-124 kg/m2 per year and the value are related and proportional to the correct human environmental control (water flux control).
文摘Outward Foreign Direct Investment (OFDI) from emerging economies has begun to increase significantly and has been growing at a faster pace than Foreign Direct Investment (FDI) from the developed world. This research seeks to assess the impact of Chinese acquisitions and their implications for the "Made in Italy" luxury sector and its firms. This paper presents a cross-case analysis of two Chinese acquisitions in order to provide some in-depth insights into the influences and the motives driving Chinese firms to invest in the luxury Made in Italy sector, the patterns and modes of the Chinese acquisitions as well as the competitive strategies and the distinctive challenges that both investors and acquired firms have to face. From the findings, it emerges that both the investor and the acquired firm need to overcome several key challenges to be mutual benefits from the acquisition.
基金supported by the China 111 Project (B17005)the financial support received by the Parthenope University of Napoli under ‘‘Bando di sostegno alla ricerca individuale per il triennio 2015–2017."partly supported by the U.S.–Italy Fulbright Commission and Parthenope University through a Fulbright Scholar grant to Theodore Endreny
文摘Climate conditions play a crucial role in the survival of mountain communities, whose survival already critically depends on socioeconomic factors. In the case of montane areas that are prone to natural haz-ards, such as alpine slope failure and debris flows, climatic factors exert a major influence that should be considered when creating appropriate sustainable scenarios. In fact, it has been shown that climate change alters the availability of ecosystem services (ES), thus increasing the risks of declining soil fertility and reduced water availability, as well as the loss of grassland, potential shifts in regulatory services (e.g., protection from natural hazards), and cultural services. This study offers a preliminary discussion on a case study of a region in the Italian Alps that is experiencing increased extreme precipitation and erosion, and where an isolated and historically resilient community directly depends on a natural resource econ- omy. Preliminary results show that economic factors have influenced past population trends of the Novalesa community in the Piemonte Region in northwest Italy. However, the increasing number of rock fall and debris flow events, which are triggered by meteo-climatic factors, may further influence the livelihood and weflbeing of this community, and of other similar communities around the world, Therefore, environmental monitoring and data analysis will be important means of detecting trends in landscape and climate change and choosing appropriate planning options. Such analysis, in turn, would ensure the survival of about 10% of the global population, and would also represent a possibility for future economic development in critical areas prone to poverty conditions.
文摘In order to assess the seismic hazard in an area with high seismogenic potential as the Messina Straits is, we employed the Cornell’s probabilistic approach, implemented by Bender and Perkins in the SEISRISKⅢcode,which allows calculating the expected ground motion.We considered all the earthquakes with magnitude M_s】4.0 reported in the CPTI04 catalogue and located in the seismogenic zones of Southern Italy(ZS9),which are able to
文摘The Calabria-Peloritani Arc is one of the most seismically active regions of Southern Italy.The most damaging event(Ⅰ0=ⅪMSK)occurred on December 28th,1908 in the Messina Straits area.This event,which caused at least 85000 casualties and widespread damage,has been identified as the greatest European seismic disaster of the 20th century.
文摘Debris flows play an important role among natural hazards in mountainous areas of Italy.This paper provides an overview on the recent research on debris flows conducted in italy, taking into account both hydraulic and geomorphological studies. Moreover,t
文摘AIM:To investigate the role of protein tyrosin phosphatase 22(PTPN22),maternal age at conception and sex on susceptibility and age at onset of type 1 diabetes(T1D)in Continental Italy and Sardinian populations.METHODS:Three hundred seventy six subjects admitted consecutively to the hospital for T1D and 1032healthy subjects as controls were studied in Continental Italy and 284 subjects admitted consecutively to the hospital for T1D and 5460 healthy newborns were studied in Sardinia.PTPN22 genotype was determined by DNA analysis.Maternal age at conception and age at onset of disease were obtained from clinical records.χ2 test of independence,student t test for differences between means and odds ratio analysis were carried out by SPSS programs.Three way contingency table analysis was carried out according to Sokal and Rohlf.RESULTS:The pattern of association between PTPN22and T1D is similar in Continental Italy and Sardinia:the proportion of*T allele carriers is 13.6%in T1D vs6.7%in controls in Continental Italy while in Sardinia is 7.3%in T1D vs 4.4%in controls.The association between T1D and maternal age at conception is much stronger in Sardinia than in Italy:the proportion of newborn from mother aging more than 32 years is89.3%in T1D vs 32.7%in consecutive newborn in Sardinia(P<10-6)while in Continental Italy is 32.2%in T1D vs 19.1%in consecutive newborns(P=0.005).This points to an important role of ethnicity.A slight prevalence of T1D males on T1D females is observed both in Continental Italy and Sardinia.PTPN22 genotype does not exert significant effect on the age at onset neither in Continental Italy nor and Sardinia.Maternal age does not influence significantly age at onset in Italy(8.2 years in T1D infants from mothers aging32 years or less vs 7.89 years in T1D infants from mothers aging more than 32 years:P=0.824)while in Sardinia a border line effect is observed(5.75 years in T1D infants from mothers aging 32 years or less vs7.54 years in T1D infants from mothers aging more than 32 years:P=0.062).No effect of sex on age at onset is observed in Continental Italy while in Sardinia female show a lower age at onset of T1D as compared to males(8.07 years in males vs 6.3 years in females:P=0.002).CONCLUSION:The present data confirm the importance of ethnicity on susceptibility and on the age at onset of T1D.
文摘Fagonia cretica L. is an important component of Mediterranean dry grasslands and a rare and isolated species of Italian flora. In this study, an assessment is presented on the distribution, habitat, and conservation status of F. cretica in Italy. The results of field investigation and herbarium analysis show that this species grows in a small area within the southern Calabria region characterized by a warmest and driest Mediterranean climate on the Italian peninsula. F. cretica is a semi-desert plant species growing in Italy in only one peripheral and isolated population at the northern limit of its distribution. Plant community analysis, using the phytosociological method, shows that F. cretica grows in wintergreen perennial dry grasslands dominated by Lygeum {partum and Hyparrhenia hirta. F. crelica plant communities are located in thermo-xeric habits such as south-, southeast- and east-facing slopes on clays and sandy clays in southern Calabria. The population of F. cretica is fragmented in six neighbouring localities, with two of which belonging to a Site of Community Importance (SC1). The conservation status of F. cretica population is not very good, and is defined as "Critically Endangered" in accordance with IUCN criteria. There are many threats affecting the F. crelica population in ltaly, primarily the changes in land uses due to urban expansion and reforestation with exotic plants. The southern end of the Italian peninsula hosts other plants from thermo-xeric habits that do not adapt to the current local climate. This territory can be considered as a microrefugia for plants currently distributed in the arid territory of the southern Mediterranean. These results contribute to the discussion of some conservation measures, and the possibility of establishing a micro-reserve. For all these reasons, we propose to include F. cretica in the lists of protected plant species at regional (Calabria) and country (Italy) scales in Italy.
文摘The conceptual hydrogeological model of the Viterbo thermal area in central Italy and the yield of the groundwater sys- tem have been examined. This area is of great geothermal interest. Through new investigations, three overlapping aquifers have been found. This study examines in detail the two shallower aquifers, characterized by different hydraulic and chemical characteristics. The first aquifer is related to the regional groundwater flow of the Cimino-Vico volcanic system and is generally characterized by cold, fresh waters used for irrigation and drinking water supply. The second aquifer, i.e. the thermal aquifer, supply thermal spas and public pools;it is present where the local hydrostratigraphic, structural and geothermal conditions permit a relatively active flow of higher salinity thermal waters (40?C - 62?C). These two aquifers interact vertically and laterally, giving rise to mixed waters circulating in the first aquifer. The first aquifer is recharged by direct infiltration and inflow from regional groundwater, as well as inflow from the second aquifer. The yield of the thermal aquifer is at least 170 L/s, discharging into thermal springs and wells, besides feeding the shallow aquifer vertically and laterally. Even if a future development of the second aquifer is potentially achievable on a global scale, the exploitation of the thermal waters is strictly dependent on the specific local hydrogeological equilibrium between the overlapping aquifers, different from place to place. The case study highlights that, in the volcanic hydrogeological environment, one of the most stringent constraints in determining the correct usage of a resource is the variable level of interaction of groundwater with different qualities.
文摘A three-phase pesticide transport model is used to verify by numerical simulation, the influence of different parameters on infiltration through soil and/or surface runoff processes. Simulations are performed for a typical sandy loam potato field of Italy’s Fucino Plain, to explain the occurrence of measured concentrations of pesticides (mainly Linuron) in both surface waters and groundwater. Simulations take into account agricultural practices, climatic conditions, and soil characteristics. Results focus on the role of rainfall events and irrigation, of related infiltration amount and distribution, and of root zone thickness in influencing pesticide fate and its possible concentration increase through the years. Modeling results positively fit with the background knowledge of the Plain hydrology, showing the prevalence of surface transport and a scarce possibility for pesticides to reach groundwater in an average rainfall/irrigation scenario. Meanwhile, specific water management strategies are suggested to limit the occurrence of local groundwater pollution, related to high aquifer vulnerability zones, controlling inappropriate irrigation and pesticide application.
文摘Organized by Consiglio Nazional delle Ricerche (CNR), Gruppo Nedonale diIdraulice(GNI) with the support of the Ministry of Public Works and under the auspices of theCoastal Engineering Research Council(CERC) of the American Society of CivilEngineering(ASCE), and co-sponsored by the international Association for Hydraulic of Navi-gation Congress(PIANC) and by the Associazione di Ingegneria Offshore e Marina(AIOM).Aim
文摘This paper presents the results of the investigations, driven by different techniques, including environmental tracers and geophysical methods, in the aim of better understand the causes of the current salt-water intrusion in the Pontina Plain, in the south of the Lazio Region (Italy). In the last 50 years many investigation campaigns have been carried out to evaluate the evolution of salt-water intrusion. This is an area with a strong man-made residential and tourist impact and, in the some cases, it is characterized by intensive agricultural practices. Therefore, it can be affected not only by salt-water intrusion, but by the salinization of its groundwater also due to other factors. All these factors have led the Pontina Plain to a groundwater situation which makes the groundwater resource management and the planning of their future exploitation very difficult.
文摘The paper proposes a study for the delineation of protection zones in the main discharge area of the Gran Sasso aquifer (Central Italy). At this aim, starting from a detailed geological and hydrogeological reconstruction, the study was divided into the following phases: 1) development of a conceptual model of water flow in the study area;2) creation of a 3D numerical model in order to simulate the groundwater flow in saturated conditions, both at the basin and at fine-scale;3) flow path analysis through deterministic and stochastic approaches;4) assessment of the aquifer vulnerability based on a geomorphological analysis of the catchment area. Conceptual and numerical models were then used to delineate protection zones for wells and springs with chronological criterion and geomorphological-structural criterion (based on the EPIK method). The results show that with a chronological approach protection zones are located along the main flow directions, corresponding to the areas surrounding wells and springs with high hydraulic conductivity values (faults and thrusts) within the satured zone. On the contrary, the geomorphological method has found some important protection zones also quite far from wells and springs, in areas characterized by quick infiltration processes. The protection zones delineated with the stochastic method were finally intersected by the vulnerability map obtained with the EPIK method, to take into account both filtration and infiltration processes. The results show the local vulnerability of the groundwater to the pollution, with protection zones extending 1 to 5 km towards northeast from springs and wells.