Logistic Regression Analysis on the Correlation between Physical Diseases and Life Events and Depression in the Elderly

[Objectives]This study was conducted to explore the effects of physical diseases and life events on depression among urban elderly people.[Methods]Five hundred urban elderly people in Shiyan City were selected using a convenient sampling method to investigate and diagnose depression using the Geriatric Mental State Schedule and its accompanying computer diagnostic system.The Minimum Data Set(MDS)and related factor survey form were used to investigate physical diseases and life events,and statistical analysis was conducted using methods such as logistic regression analysis and factor analysis.[Results]The prevalence rates of angina,stroke,or partial paralysis,migraine,vision problems,hyperthyroidism or hypothyroidism,as well as the number of physical diseases were significantly higher in elderly depression patients than in objects free of depression.Stroke or partial paralysis[OR(95%CI)=6.389(1.684,24.237)],emotional trauma events[OR(95%CI)=1.438(1.069,1.934)]and adverse health and economic events[OR(95%CI)=1.652(1.099,2.483)]were risk factors for late life depression(LLD).[Conclusions]Some physical diseases and life events may affect the onset process of depression in urban elderly people,and various measures need to be taken to reduce the risk of physical diseases and life events on depression.

Coping as a Mechanism Linking Stressful Life Events and Mental Health Problems in Adolescents

Objective Although stressful life events represent an etiologic factor of mental health problems in adolescents, few studies have been conducted to address mechanisms linking the stress-psychopathology relation. The present study was designed to examine coping as a mediate factor on the relationship between stressful life events and symptoms of anxiety and depression. Methods The participants were 13 512 students from eight cities of China, who participated in a school-based survey. Data were collected by a questionnaire comprising coping, stressful life events, anxiety, and depressive symptoms. As a model, a series of regression equations were used to examine whether coping mediated the association between stressful life events and symptoms of anxiety and depression. Results Each dimension of stressful life events showed significant correlation with anxiety, depression and coping （all P〈0.001）. In the model to analyze mediate effects, all standardized coefficients （β） were significant （all P〈0.01）, indicating marked mediator effects. Furthermore, negative coping might account for more mediate effects than positive coping on this relationship. Conclusion Coping partially mediated the relationship between stressful life events and mental health during adolescence. This study highlighted an important public health priority for preventive interventions targeting stress-related psychopathology, and for further promoting adolescents＇ mental health.

Psychological impact of chronic hepatitis C:Comparison with other stressful life events and chronic diseases

AIM： To examine the psychological impact of chronic hepatitis C （CHC） diagnosis in a large cohort of CHC patients as compared with other stressful life events and chronic diseases carrying a risk of life-threatening complications. METHODS： One hundred and eighty-five outpatients with compensated CHC were asked to self-grade, using a 100-mm visual analogue scale （VAS）, the degree of stress caused by the learning of CHC diagnosis and the perceived severity of their disease. Diagnosis-related stress was compared to four other stressful life events and perceived CHC severity was compared to four other common chronic diseases. RESULTS： Learning of CHC diagnosis was considered a major stressful event （mean ± SD scores： 72±25）, significantly less than death of a loved-one （89±13, P〈0.0001） and divorce （78 ± 23, P〈0.007）, but more than job dismissal （68 ± 30, P〈 0.04） and home removal （26±24, P〈 0.0001）. CHC was considered a severe disease （74± 19）, after AIDS （94±08, P〈 0.001） and cancer （91± 11, P〈 0.001）, but before diabetes （66±23, P〈0.001） and hypertension （62±20, P〈0.001）. Perceived CHC severity was not related to the actual severity of liver disease, assessed according to Metavir fibrosis score. In multivariate analysis, diagnosisrelated stress was related to perceived disease severity （P〈0.001）, trait anxiety （P〈 0.001） and infection through blood transfusion （P〈 0.001）. CONCLUSION： Our results show the considerable psychological and emotional burden that a diagnosis of CHC represents, even in the absence of significant liver disease. They should be taken into account when announcing a diagnosis of CHC in order to reduce its negative effects.

Causation mechanism of coal miners' human errors in the perspective of life events

In order to effectively decrease the safety accidents caused by coal miners’human errors,this paper probes into the causality between human errors and life events,coping,psychological stress,psychological function,physiological function based on life events’vital influence on human errors,establishing causation mechanism model of coal miners’human errors in the perspective of life events by the researching method of structural equation.The research findings show that life events have significantly positive influence on human errors,with a influential effect value of 0.7945 and a influential effect path of‘‘life events—psychological stress—psychological function—physiological function—human errors’’and‘‘life events—psychological stress—physiological function—human errors’’.

Investigation of stressful life events in patients with systemic sclerosis

Objective: To assess the occurrence of stressful life events in the year before the initiation of systemic sclerosis. Methods: A consecutive series of 40 patients with systemic sclerosis (mean age (56.3±11.9) years, mean disease duration (4.3±3.1) years; 32 females and 8 males), including 28 with diffuse cutaneous scleroderma and 12 with limited cutaneous scleroderma, were evaluated. A control group of 40 healthy subjects free of systemic sclerosis also was included. Socioeconomic status was inves- tigated and Paykel's interview for recent life events (a semi-structured research interview covering 64 life events) was conducted. Results: Patients with systemic sclerosis showed higher percentages of lower education (72.5%) and working class (82.5%), and reported more stressful life events (P<0.05), such as exits (P<0.05), undesirable events (P<0.01), and uncontrolled events (P<0.001), when compared with the control. More events that had an objective negative impact (P<0.001) were also reported in systemic sclerosis patients than in the control. These results are in accordance with a multifactorial model of pathogenesis in systemic sclerosis. Conclusion: We reported a strong relationship between stressful life events and the initiation of systemic sclerosis. Our findings are consistent with current understanding of the extensive links of behavioral responses to stress with neurophysiological and biochemical processes.

Highly Secure Residents Life Event Management System Based on Blockchain by Hyperledger Fabric

This article describes the design and implementation of Residents Life Event Management System (hereinafter called as RLEMS) with high level reliability and security by blockchain technology. The data access environment provided by blockchain is highly secure and trustworthy. In Blockchain system, some data fragments are grouped into one piece called as blocks, and all blocks are connected to create a chain of blocks in database. When blocks are connected, hash value is used to connect blocks properly. Blockchain technology enables highly secure and reliable data management system under relatively poor ICT environment. For example, developing countries such as African countries do not have sufficient ICT environment. Therefore adopting blockchain technology is suitable for such countries. Based on this consideration, we have started to build RLEMS on the blockchain system. In previous work, we used the MultiChain as a blockchain platform. However, as MultiChain platform is mainly for private blockchain system, it is not suitable for government-level data management system. Therefore, we tried to use another blockchain framework. We selected Hyperledger Fabric which was developed by Linux Foundation. It enables to implement all styles of blockchain system. This article describes the design and implementation of RLEMS by using Hyperledger Fabric. Furthermore, to provide the best user experience, we also built the web application interface with Java web application framework named PrimeFace. The implementation of a prototype revealed that the Hyperledger Fabric blockchain technology is more suitable than MultiChain.

An Examination of the Validity of the Differentiation-of-Self Hypothesis and Its Mechanism Related to Negative Life Event Aversion among Japanese University Students

This study examined the validity of the differentiation-of-self hypothesis for Japanese university students, and its mechanism in relation to negative life event aversion. Although the differentiation-of-self hypothesis is accepted as one of the basic hypotheses in the clinical field of family therapy in Japan, empirical studies on the subject are scarce. Further, there are few studies, internationally, on its mechanism. A questionnaire survey was conducted with university students (n = 250) to measure their differentiation of self, maladaptive states, and negative life event aversion. Compared to the better-differentiated group, the less-differentiated group had higher scores both for maladaptive states—somatic symptoms (t(223) = -2.70, p = 0.008), social dysfunction (t(211.00) = -3.30, p = 0.001), and severe depression (t(208.78) = -4.08, p < 0.001)—and negative life event aversion—interpersonal domain (t(223) = -3.96, p < 0.001) and achievement domain (t(223) = -3.83, p < 0.001). The results supported the validity of the differentiation-of-self hypothesis for Japanese university students, and that cognitive tendencies toward negative life events may be part of the mechanism for less-differentiated individuals’ subsequent vulnerability. This suggests the effectiveness of cognitive interventions.

Relation between Life Events and Intimacy and Relational Satisfaction in Men from 40 Years of Age

The present study consists of verifying the relation between life events mid intimacy and relational satisfaction in men from 40 years of age. The sample consisted of 70 males aged 40 years or older （M= 51.6, SD = 8.1）. In order to obtain the results, all the described life events were analyzed and the intimacy and relational satisfaction questionnaire, ＂Revised Dyadic Adjustment Scale＂ （RDAS） was used. It was confirmed that there were significant differences in intimacy and relational satisfaction, comparing the subjects who pointed out very positive life events with the subjects who pointed out very negative life events. Regarding to the first group, there was a greater degree of satisfaction with intimacy, a greater agreement between the couple, a higher participation in joint activities and few disagreements within the relationship. However, the duration of the relationship and partner age are higher in the second group. It was also verified that subjects between 40 and 50 years old presented a higher degree of satisfaction with intimacy, comparing with subjects between 51 and 79 years, although the latter had longer relationships and that partner age was older.

The effect of life events, personality and coping strategies on depressive of undergraduates

AIM:To study the effect of life events,personality and coping strategies on depression of undergraduates.METHOD:Fifteen hundred students were selected in the three schoolyards of Central South University.Life Events Scale,Coping Strategies Scale,Eysenck Personality Questionnaire(EPQ)and Self rating Depressive Scale (SDS) were used to assess all samples.RESULTS:The score of SDS was (42±8).The life events came from relationship of person,stress of study,loss,punishment,health and adaptation,love and family were higher in the SDS group of higher score,which the SDS group of higher score took more negative coping strategies than the normal score.CONCLUSION:The rate of depression was higher in undergraduates,which need more attention on it.More life events, introversive instability personality and negative coping strategies may be the main risk factors that caused depression.

The association between critical life events, sociodemographic data and physical activity in the development of myocardial infarction in smokers and ex-smokers

Background: Psychosocial factors attract interest in investigating the occurrence of cardiovascular disease. Design This study aimed to examine the impact of critical life events on the development of myocardial infarction in smokers and ex-smokers. We hypothesized that critical life events increase the risk of the disease. Methods: Data were taken from the Cologne Smoking Study (CoSmoS), a retrospective multicentre case-control study that examines which psychosocial factors may lead to a higher risk for smokers and ex-smokers of suffering from a myocardial infarction. Our sample consisted of n = 278 myocardial infarction participants and control participants. Both groups had a history of smoking. Logistic regression was used in the analysis. Results: The study results of the smoking and ex-smoking participants showed that sociodemographic data like gender and age have an effect on the development of myocardial infarction. Physical activity seems to offer protection aganist myocardial infarction. Final, the unexpected result that the experience of at least one critical life event seems to have a positive effect on health and so lowers the risk of myocardial infarction. Conclusions: Socio-demographic data and physical activity have an effect on the development of myocardial infarction. Participants with experience of critical life events appear to be strengthened after the events and possess adequate resources to protect their health.

Stressful life events,psychosocial health and general health in preschool children before age 4

Background The impact of stressful life events(SLEs)in early childhood is often ignored.We aimed to examine longitudinal associations between SLEs and psychosocial and general health in preschool children.Methods Twelve SLEs occurring before the age of 24 months were assessed and categorized by frequency(no events,1-2 SLEs,and>2 SLEs)and overall tension(no events,low,and high)(n=1431).Psychosocial and general health were meas-ured three times at the age of 24,36 and 45 months.The associations were examined by logistic regression models using generalized estimating equations to handle repeated measurements.Results Half(48.4%)of the families experienced SLEs,and 23.8%perceived high-tension SLEs before the children were aged 24 months.Gender differences were observed in the association between SLEs and psychosocial health.Compared to girls without SLEs,girls who experienced>2 SLEs[OR=3.31,95%confidence interval(CI)2.05-5.35]or high-tension SLEs(OR=3.01,95%CI 2.07-4.39)had higher odds of psychosocial problems from 24 to 45 months.The odds ratios in boys were 2.10(95%CI 1.36-3.24)and 1.47(95%CI 1.06-2.03),respectively.Moreover,only girls'risk of psychosocial problems increased after experiencing 1-2 SLEs(OR=2.15,95%CI 1.54-3.00)or low-tension SLEs(OR=1.90,95%CI 1.31-2.74).Regarding general health,children who experienced>2 SLEs(OR=1.96,95%CI 1.21-3.18)and high-tension SLEs(OR=1.60,95%CI 1.12-2.28)had higher odds of poor general health from 24 to 45 months.Conclusions The findings emphasized that young children's psychosocial and general health can be impacted by experienc-ing SLEs in early childhood.Attention and adequate support for families experiencing SLEs are needed to minimize the potential negative effect of SLEs on child health,particularly in girls.

Perinatal Stroke and Apparent Life-Threatening Event: A Case Report

To analyze how the multidisciplinary clinical, biohumoral, instrumental approach to ALTE (Apparent Life Threatening Event) episode may discover cardiovascular disease in the newborn. Introduction: In the first year of life ALTEs concern 0.8% of access to Pediatric Emergency Department. The cause of apparent life-threatening events (ALTEs) in infants reflects a differential diagnosis that includes an array of congenital or acquired disorders. Approximately 10% - 25% of ap-parent life-threatening events may remain unexplained following a thorough evaluation. Case re-port: B. E., a 2-month-old child, in wellbeing, shortly before meal, during sleep, was not responsive to repeated stimulations;he was hypotonic and unresponsive. About 15 minutes later, he pre-sented a normal tone and state of consciousness. Evaluating the referred symptoms, diagnostic protocol for ALTE was started;the Angio-MRI brain performed as second line analysis showed a focal gliotic lesion at left striatal area. The cardiological evaluation with echocardiography detected a pervium foramen ovale (PFO), with minimum shunt left-right direction. At least, biohumoral tests revealed protrombin gene heterozygosis mutation. Conclusion: Apparent Life-Threatening Events are first manifestation of stroke in infant. Discussion: This report discloses how the multidisciplinary clinical approach is essential in ALTE. The exact management of ALTE patients is very important in situations like this, when the concomitant disease is rare. In fact, arterial stroke incidence in children > 28 days of life is estimated between 1.2 and 7.9 cases/100,000 child-ren/year. However, in the last 20 years, we observed an increased incidence of stroke, probably related to two main causes: a greater attention for this disease and a major survival of children with pathology that arrange for stroke thanks to a better prevention. In conclusion, it’s a fundamental multidisciplinary approach even in following months after the events.

负性生活事件与青少年网络欺凌行为的关系——愤怒反刍的中介作用和网络去抑制的调节作用

为探讨负性生活事件对青少年网络欺凌行为的影响,以及愤怒反刍和网络去抑制在这一影响中的作用,采用青少年生活事件量表、愤怒反刍量表、网络欺凌行为问卷和网络去抑制量表对610名青少年进行问卷调查。结果表明:其一,在控制性别和年龄后,负性生活事件显著地正向预测青少年的网络欺凌行为。其二,愤怒反刍在负性生活事件与网络欺凌行为之间存在显著的中介作用。其三,网络去抑制在愤怒反刍与网络欺凌行为之间起到显著的调节作用;青少年的网络去抑制水平越高,愤怒反刍对网络欺凌行为的正向预测作用越强。这一研究结果对减少网络欺凌行为的干预措施提供了新的视角。

循序渐进的运动康复护理对慢性心衰患者运动耐力、生活质量及不良心脏事件的影响

目的探究循序渐进的运动康复护理对慢性心衰患者运动耐力、生活质量及不良心脏事件的影响。方法选取2022年6月-2023年6月我院收治的106例慢性心衰患者进行研究。以随机数字表法均分为2组。对照组(53例):基础护理。观察组(53例):循序渐进的运动康复护理。比较6 MWD、生活质量、不良心脏事件、满意度。结果干预前,两组6 MWD相比差异不显著(t=0.267,P=0.790),干预3个月后,两组6 MWD均显著提升(t=11.710,P=0.000,t=8.469,P=0.000),且观察组(403.18±62.11)m高于对照组(375.51±68.43)分,差异显著(t=2.180,P=0.032)。干预前,两组生活质量评分相比差异不显著(t=1.690,P=0.094),干预3个月后,两组生活质量评分均显著提升(t=14.053,P=0.000,t=8.409,P=0.000),且观察组(47.11±3.16)分高于对照组(42.34±3.28)分,差异显著(t=7.625,P=0.000)。与对照组16.98%的心衰加重、心源性再入院、急性心肌梗死、心律失常等不良心脏事件总发生率相比,观察组(3.77%)显著降低,差异显著(χ^(2)=4.970,P=0.026)。观察组满意度(90.57%)优于对照组(75.47%),差异显著(χ^(2)=4.283,P=0.039)。结论循序渐进的运动康复护理在提升慢性心衰患者运动耐力方面有积极意义。该护理能够提高患者生活质量及满意度,降低不良心脏事件的发生率。

大学新生负性生活事件和神经质及运动频次与抑郁症状的关系

目的:分析大学新生负性生活事件与抑郁症状的关系,以及神经质的中介效应与运动频次的调节作用。方法:抽取8079名大学新生,采用患者健康问卷评估抑郁症状,艾森克人格问卷-神经质分量表评估神经质,自编问卷评估经历过的负性生活事件数量、运动频次。采用Process插件中的模型4检验神经质的中介效应,模型7检验运动频次的调节作用。结果:负性生活事件数量与抑郁症状得分呈正相关(r=0.16,P<0.01),与神经质得分呈正相关(r=0.26,P<0.01)。神经质得分与抑郁症状得分呈正相关(r=0.52,P<0.01)。神经质得分在负性生活事件数量与抑郁症状得分间起部分中介作用,中介效应占比为78.4%,运动频次得分在负性生活事件数量和神经质得分之间起调节作用(β=-0.05,P<0.05)。结论:负性生活事件与抑郁症状相关,神经质具有中介作用,运动频次可调节负性生活事件和神经质。

心理韧性缓冲压力生活事件与青少年学业倦怠之间的非线性关系

压力生活事件对青少年的适应性发展具有潜在危害。本研究聚焦于学业倦怠,进一步探索压力生活事件与学业倦怠不同维度之间的关系,以及心理韧性的潜在缓冲作用。基于对3309名青少年的有效调查数据,本研究发现:(1)压力生活事件与青少年学业倦怠的消极核心维度之间具有非线性关系,随着压力生活事件的累积,学业倦怠水平增加的速度由快变慢,表现为饱和模型;(2)心理韧性可以充当缓冲性保护机制,相较于低心理韧性个体,对高心理韧性个体而言,压力生活事件与学业倦怠之间的非线性关系减弱,随着压力生活事件的累积,心理韧性的缓冲性效应显现出来;心理韧性无法调节压力生活事件与学业效能之间的非线性关系。研究结果支持饱和模型而非门槛模型,也为韧性分析框架下不同类型适应指标的区分提供了证据。

负性生活事件对大学生手机依赖的影响:有调节的中介模型

目的:探究负性生活事件对大学生手机依赖的影响机制,考察归属需要和领悟社会支持在其中的中介和调节作用。方法:采用负性生活事件强度、归属需要满足程度、领悟社会支持水平和手机依赖程度的问卷对502名武汉高校大学生进行了问卷调查。结果:①负性生活事件与手机依赖显著正相关(r=0.392,P<0.01)。②归属需要满足在负性生活事件与手机依赖之间起部分中介作用(β=-0.280,t=-6.915,P<0.001,中介作用占总效应的18.64%)。③领悟社会支持对直接效应(β=0.330,t=10.997,P<0.001)和中介效应的前半段路径(β=-0.214,t=-7.060,P<0.001)起着调节作用,在直接路径中,低领悟社会支持会加剧负性生活事件对手机依赖的影响。在中介路径中,高领悟社会支持时,高负性生活事件对归属需要的影响较小,进而对手机依赖的影响较小。结论:负性生活事件能够显著预测大学生手机依赖,归属需要在负性生活事件和手机依赖之间起部分中间作用,“负性生活事件-手机依赖”的直接路径和“负性生活事件-归属需要-手机依赖”的前半段路径受到领悟社会支持的调节。

Unraveling the complexities of adolescent depression:A call for action

The adolescent years are a period of profound change,both physically and psychologically.For many,these years are marked by excitement and exploration,but for others,they are fraught with challenges that can lead to significant mental health issues.Depression,in particular,has become an increasingly prevalent concern among adolescents worldwide,and its multifaceted etiology requires a comprehensive approach to understanding and intervention.A recent study on the relationships among negative life events,dysfunctional attitudes,social support,and depressive symptoms in Chinese adolescents offers valuable insights into the complex interplay between various factors contributing to adolescent depression.The authors explore a moderated mediation model to better understand how these factors interact with and contribute to the onset of depression.This article aims to delve into the key findings of the study,highlight its implications for clinical practice,and encourage further research in this critical area.

Enhancing adolescent mental health through cognitive and social support:Insights from study on depression in Chinese adolescents

Adolescent depression is a growing global health concern,affecting 14%of adolescents and leading to severe consequences such as academic failure,substance abuse,and suicidal ideation.The study by Yu et al,investigates the cognitive and social factors influencing depression in 795 Chinese adolescents.Findings reveal that negative life events(NLEs)and dysfunctional attitudes are strongly associated with depressive symptoms,while social support moderates the impact of NLEs but not dysfunctional attitudes.The study highlights the need for cognitivebehavioural interventions targeting perfectionism and autonomy,and the importance of strengthening social support systems in schools and communities.Culturally sensitive,holistic approaches to adolescent mental health are crucial for addressing both the internal vulnerabilities and external pressures contributing to depression.Further research is needed to explore the roles of peer and parental support and the long-term effects of these factors across diverse cultural contexts.