Results of oxidation 2-(N-acetylamine)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)-propionic acid oxygen depend on temperature. At 55℃?- 60℃, 2,4-di-tert-butylbicyclo(4,3,1)deca-4,6-dien-8-(N-acetylamine)-3,9-dion-1-oxa i...Results of oxidation 2-(N-acetylamine)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)-propionic acid oxygen depend on temperature. At 55℃?- 60℃, 2,4-di-tert-butylbicyclo(4,3,1)deca-4,6-dien-8-(N-acetylamine)-3,9-dion-1-oxa is formed. The constitution is based on dates of spectrums 1Н and 13С NMR. At 95℃?- 97℃, mixtures of 2,4-di-tert-butylbicyclo(4,3,1)deca-4,6-dien-8-(N-acetylamine)-3,9-dion-1-oxa and of 6,8-di-tert-butyl-3-(N-acetylamine)spiro(4,5)deca-1-oxa-5,8-dien-2,7-dione are produced. Structures are calculated by the method of Hartrii-Foka. Values of enthalpies and of entropies allow to assume dynamic isomerism.展开更多
The esterification of carboxylic acid with alcohol in the presence of catalytic amounts of mineral acids is one of the most methods for preparing esters.The catalysts generally preferred are sulfuric acid or p-toluene...The esterification of carboxylic acid with alcohol in the presence of catalytic amounts of mineral acids is one of the most methods for preparing esters.The catalysts generally preferred are sulfuric acid or p-toluenesulfonic acid.But the products esters were racemic when（S）-3-（2′-oxocyclohexyl） propionic acid reacts with alcohols in the presence of sulfuric acid or with p-toluenesulfonic acid as catalyst.We replace sulfuric acid with Fe2(SO4)3·xH2O as the catalyst.The optical compound（S）-methyl-3-（2′-oxocyclohexyl）propionate,（（S）-ethyl-3-）（2′-oxocyclohexyl）propionate and（S）-n-butyl-3-（2′-oxocyclohexyl）propionate were obtained.In this paper we also reported that cyclohexanone reacted with methyl acrylate in the presence of potassium thiazolidine-2-thione-4-carboxylate（R）TTCA·K as the chiral catalyst to afford optically active（S）-3-（2′-oxocy-clohexyl） propionate.The mechanism of reaction of cyclohexanone with methyl acrylate in the presence of（R）TTCA·K as the catalyst would be a complex process.展开更多
文摘Results of oxidation 2-(N-acetylamine)-3-(3,5-di-tert-butyl-4-hydroxyphenyl)-propionic acid oxygen depend on temperature. At 55℃?- 60℃, 2,4-di-tert-butylbicyclo(4,3,1)deca-4,6-dien-8-(N-acetylamine)-3,9-dion-1-oxa is formed. The constitution is based on dates of spectrums 1Н and 13С NMR. At 95℃?- 97℃, mixtures of 2,4-di-tert-butylbicyclo(4,3,1)deca-4,6-dien-8-(N-acetylamine)-3,9-dion-1-oxa and of 6,8-di-tert-butyl-3-(N-acetylamine)spiro(4,5)deca-1-oxa-5,8-dien-2,7-dione are produced. Structures are calculated by the method of Hartrii-Foka. Values of enthalpies and of entropies allow to assume dynamic isomerism.
文摘The esterification of carboxylic acid with alcohol in the presence of catalytic amounts of mineral acids is one of the most methods for preparing esters.The catalysts generally preferred are sulfuric acid or p-toluenesulfonic acid.But the products esters were racemic when（S）-3-（2′-oxocyclohexyl） propionic acid reacts with alcohols in the presence of sulfuric acid or with p-toluenesulfonic acid as catalyst.We replace sulfuric acid with Fe2(SO4)3·xH2O as the catalyst.The optical compound（S）-methyl-3-（2′-oxocyclohexyl）propionate,（（S）-ethyl-3-）（2′-oxocyclohexyl）propionate and（S）-n-butyl-3-（2′-oxocyclohexyl）propionate were obtained.In this paper we also reported that cyclohexanone reacted with methyl acrylate in the presence of potassium thiazolidine-2-thione-4-carboxylate（R）TTCA·K as the chiral catalyst to afford optically active（S）-3-（2′-oxocy-clohexyl） propionate.The mechanism of reaction of cyclohexanone with methyl acrylate in the presence of（R）TTCA·K as the catalyst would be a complex process.
