Running safety assessment and tracking irregularity parametric sensitivity analysis of high-speed maglev train-bridge system are of great concern,especially need perfect refinement models in which all properties can b...Running safety assessment and tracking irregularity parametric sensitivity analysis of high-speed maglev train-bridge system are of great concern,especially need perfect refinement models in which all properties can be well characterized based on various stochastic excitations.A three-dimensional refined spatial random vibration analysis model of high-speed maglev train-bridge coupled system is established in this paper,in which multi-source uncertainty excitation can be considered simultaneously,and the probability density evolution method(PDEM)is adopted to reveal the system-specific uncertainty dynamic characteristic.The motion equation of the maglev vehicle model is composed of multi-rigid bodies with a total 210-degrees of freedom for each vehicle,and a refined electromagnetic force-air gap model is used to account for the interaction and coupling effect between the moving train and track beam bridges,which are directly established by using finite element method.The model is proven to be applicable by comparing with Monte Carlo simulation.By applying the proposed stochastic framework to the high maglev line,the random dynamic responses of maglev vehicles running on the bridges are studied for running safety and stability assessment.Moreover,the effects of track irregularity wavelength range under different amplitude and running speeds on the coupled system are investigated.The results show that the augmentation of train speed will move backward the sensitive wavelength interval,and track irregularity amplitude influences the response remarkably in the sensitive interval.展开更多
The application of microorganisms as probiotics is limited due to lack of safety evaluation.Here,a novel multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 with aroma-producing properties was identified from ...The application of microorganisms as probiotics is limited due to lack of safety evaluation.Here,a novel multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 with aroma-producing properties was identified from marine mangrove microorganisms.Its safety and probiotic properties were assessed in accordance with phenotype and whole-genome sequencing analysis.Results showed that the genes and phenotypic expression of related virulence,antibiotic resistance and retroelement were rarely found.Hyphal morphogenesis genes(SIT4,HOG1,SPA2,ERK1,ICL1,CST20,HSP104,TPS1,and RHO1)and phospholipase secretion gene(VPS4)were annotated.True hyphae and phospholipase were absent.Only one retroelement(Tad1-65_BG)was found.Major biogenic amines(BAs)encoding genes were absent,except for spermidine synthase(JA9_002594),spermine synthase(JA9_004690),and tyrosine decarboxylase(inx).The production of single BAs and total BAs was far below the food-defined thresholds.GXDK6 had no resistance to common antifungal drugs.Virulence enzymes,such as gelatinase,DNase,hemolytic,lecithinase,and thrombin were absent.Acute toxicity test with mice demonstrated that GXDK6 is safe.GXDK6 has a good reproduction ability in the simulation gastrointestinal tract.GXDK6 also has a strong antioxidant ability,β-glucosidase,and inulinase activity.To sum up,GXDK6 is considered as a safe probiotic for human consumption and food fermentation.展开更多
Extensive high-speed railway(HSR)network resembled the intricate vascular system of the human body,crisscrossing mainlands.Seismic events,known for their unpredictability,pose a significant threat to both trains and b...Extensive high-speed railway(HSR)network resembled the intricate vascular system of the human body,crisscrossing mainlands.Seismic events,known for their unpredictability,pose a significant threat to both trains and bridges,given the HSR’s extended operational duration.Therefore,ensuring the running safety of train-bridge coupled(TBC)system,primarily composed of simply supported beam bridges,is paramount.Traditional methods like the Monte Carlo method fall short in analyzing this intricate system efficiently.Instead,efficient algorithm like the new point estimate method combined with moment expansion approximation(NPEM-MEA)is applied to study random responses of numerical simulation TBC systems.Validation of the NPEM-MEA’s feasibility is conducted using the Monte Carlo method.Comparative analysis confirms the accuracy and efficiency of the method,with a recommended truncation order of four to six for the NPEM-MEA.Additionally,the influences of seismic magnitude and epicentral distance are discussed based on the random dynamic responses in the TBC system.This methodology not only facilitates seismic safety assessments for TBC systems but also contributes to standard-setting for these systems under earthquake conditions.展开更多
To solve the problem of risk identification and quantitative assessment for human-computer interaction(HCI)in complex avionics systems,an HCI safety analysis framework based on system-theoretical process analysis(STPA...To solve the problem of risk identification and quantitative assessment for human-computer interaction(HCI)in complex avionics systems,an HCI safety analysis framework based on system-theoretical process analysis(STPA)and cognitive reliability and error analysis method(CREAM)is proposed.STPACREAM can identify unsafe control actions and find the causal path during the interaction of avionics systems and pilot with the help of formal verification tools automatically.The common performance conditions(CPC)of avionics systems in the aviation environment is established and a quantitative analysis of human failure is carried out.Taking the head-up display(HUD)system interaction process as an example,a case analysis is carried out,the layered safety control structure and formal model of the HUD interaction process are established.For the interactive behavior“Pilots approaching with HUD”,four unsafe control actions and35 causal scenarios are identified and the impact of common performance conditions at different levels on the pilot decision model are analyzed.The results show that HUD's HCI level gradually improves as the scores of CPC increase,and the quality of crew member cooperation and time sufficiency of the task is the key to its HCI.Through case analysis,it is shown that STPACREAM can quantitatively assess the hazards in HCI and identify the key factors that impact safety.展开更多
This article presents a real-life project that aimed to evaluate the safety of traffic vehicles on old bridges without any prior data.The project involved various safety inspections,including conventional,static,and d...This article presents a real-life project that aimed to evaluate the safety of traffic vehicles on old bridges without any prior data.The project involved various safety inspections,including conventional,static,and dynamic load inspections and safety assessments.After conducting these tests,it was concluded that the structure of the old bridge is relatively safe,with only a few bumps.The bridge could function normally following appropriate treatment.The analysis provides valuable insights into the assessment of the quality and safety of such bridges to ensure the safe driving of heavy vehicles.展开更多
In the field of model-based system assessment,mathematical models are used to interpret the system behaviors.However,the industrial systems in this intelligent era will be more manageable.Various management operations...In the field of model-based system assessment,mathematical models are used to interpret the system behaviors.However,the industrial systems in this intelligent era will be more manageable.Various management operations will be dynamically set,and the system will be no longer static as it is initially designed.Thus,the static model generated by the traditional model-based safety assessment(MBSA)approach cannot be used to accurately assess the dependability.There mainly exists three problems.Complex:huge and complex behaviors make the modeling to be trivial manual;Dynamic:though there are thousands of states and transitions,the previous model must be resubmitted to assess whenever new management arrives;Unreusable:as for different systems,the model must be resubmitted by reconsidering both the management and the system itself at the same time though the management is the same.Motivated by solving the above problems,this research studies a formal management specifying approach with the advantages of agility modeling,dynamic modeling,and specification design that can be re-suable.Finally,three typical managements are specified in a series-parallel system as a demonstration to show the potential.展开更多
Road transport safety policies have emphasized road infrastructure safety design and engineering as a core function.However,in developing countries like Vietnam,this approach has been slower to adopt,resulting in subs...Road transport safety policies have emphasized road infrastructure safety design and engineering as a core function.However,in developing countries like Vietnam,this approach has been slower to adopt,resulting in substandard roads.In-depth studies of accident locations indicate that road environment factors contribute significantly to road accidents in Vietnam and road design features are associated with specific accident types and hazards.Proactive and reactive approaches,such as road safety audit,inspection,assessment,and treatment of hazardous locations,are necessary to ensure that the road and its environment are safe.This paper provides an overview of road safety in Vietnam in general,and Ho Chi Minh in particular,including its factors and characteristics,as well as road infrastructure safety improvements.The iRap tool for road safety inspection and assessment is highlighted as a potential method for systematically analyzing road infrastructure deficiencies and providing targeted countermeasures to improve road safety under mixed traffic conditions.展开更多
A new safety assessment method for parallel routes is presented. From the aspects of safety guard system of air traffic control(ATC) and considering the flight conflict as causing event of air collision accidents, t...A new safety assessment method for parallel routes is presented. From the aspects of safety guard system of air traffic control(ATC) and considering the flight conflict as causing event of air collision accidents, this paper fosters a four-layer safety guard of controller command, short-term conflict alerts (STCAs), pilot visual avoidance, and traffic alert collision avoidance system(TCAS). Then, the problem of parallel routes collision risk is divided into two parts:the calculation of potential flight conflict and the analysis of failure probability of the four-layer safety guard. A calculation model for controller interference times is induced. By using cognitive reliability and error analysis method(CREAM),the calculation problem to failure probability of controller sequencing flight conflicts is solved and a fault tree model of guard failure of STCA and TCAS is established. Finally, the Beijing-Shanghai parallel routes are taken as an example to be calculated and the collision risk of the parallel routes is obtained under the condition of radar control. Results show that the parallel routes can satisfy the safety demands.展开更多
In this paper,overcharge behaviors and thermal runaway(TR)features of large format lithium-ion(Liion)cells with different cathode materials(LiFePO4(LFP),Li[Ni_(1/3)Co_(1/3)Mn_(1/3)]O_(2)(NCM111),Li[Ni_(0.6)Co_(0.2)Mn_...In this paper,overcharge behaviors and thermal runaway(TR)features of large format lithium-ion(Liion)cells with different cathode materials(LiFePO4(LFP),Li[Ni_(1/3)Co_(1/3)Mn_(1/3)]O_(2)(NCM111),Li[Ni_(0.6)Co_(0.2)Mn_(0.2)]O_(2)(NCM622)and Li[Ni_(0.8)Co_(0.1)Mn_(0.1)]O_(2)(NCM811))were investigated.The results showed that,under the same overcharge condition,the TR of LFP Li-ion cell occurred earlier compared with the NCM Li-ion cells,indicating its poor overcharge tolerance and high TR risk.However,when TR occurred,LFP Li-ion cell exhibited lower maximum temperature and mild TR response.All NCM Liion cells caught fire or exploded during TR,while the LFP Li-ion cell only released a large amount of smoke without fire.According to the overcharge behaviors and TR features,a safety assessment score system was proposed to evaluate the safety of the cells.In short,NCM Li-ion cells have better performance in energy density and overcharge tolerance(or low TR risk),while LFP Li-ion cell showed less severe response to overcharging(or less TR hazards).For NCM Li-ion cells,as the ratio of nickel in cathode material increases,the thermal stability of the cathode materials becomes poorer,and the TR hazards increase.Such a comparison study on large format Li-ion cells with different cathode materials can provide deeper insights into the overcharge behaviors and TR features,and provide guidance for engineers to reasonably choose battery materials in automotive applications.展开更多
Safety assessment is one of important aspects in health management.In safety assessment for practical systems,three problems exist:lack of observation information,high system complexity and environment interference.Be...Safety assessment is one of important aspects in health management.In safety assessment for practical systems,three problems exist:lack of observation information,high system complexity and environment interference.Belief rule base with attribute reliability(BRB-r)is an expert system that provides a useful way for dealing with these three problems.In BRB-r,once the input information is unreliable,the reliability of belief rule is influenced,which further influences the accuracy of its output belief degree.On the other hand,when many system characteristics exist,the belief rule combination will explode in BRB-r,and the BRB-r based safety assessment model becomes too complicated to be applied.Thus,in this paper,to balance the complexity and accuracy of the safety assessment model,a new safety assessment model based on BRB-r with considering belief rule reliability is developed for the first time.In the developed model,a new calculation method of the belief rule reliability is proposed with considering both attribute reliability and global ignorance.Moreover,to reduce the influence of uncertainty of expert knowledge,an optimization model for the developed safety assessment model is constructed.A case study of safety assessment of liquefied natural gas(LNG)storage tank is conducted to illustrate the effectiveness of the new developed model.展开更多
Safety assessment of offshore platforms is an urgent task. Such assessments are now focusing on the structure, maintenance, and retirement of a platform. Some methods employed have many shortcomings. For example, they...Safety assessment of offshore platforms is an urgent task. Such assessments are now focusing on the structure, maintenance, and retirement of a platform. Some methods employed have many shortcomings. For example, they cannot make the reliability adequately explicable. Therefore, a mathematical tool, the unascertained measure, was introduced. First, the basic knowledge of the unascertained sets was introduced briefly. Second, the unascertained measure was defined and credible identification was set up. The method has been introduced into the fields for safety assessment of a jacket loadout procedure. Engineering practices showed that it can complete the safety assessment systematically and scientifically without any assumption. The work should have significance in theory and practice for offshore engineering.展开更多
The DFI-1 submarine pipeline was investigated using a dual-frequency side-scan sonar and a swath sounder system. More than a hundred scour pits under the pipeline were found, most of which have caused the span of the ...The DFI-1 submarine pipeline was investigated using a dual-frequency side-scan sonar and a swath sounder system. More than a hundred scour pits under the pipeline were found, most of which have caused the span of the pipeline to increase and threatened its safety. The maximum allowable free span length (MAFSL) of the pipeline was determined through the limitations re- garding maximum allowable stress under static or quasi-static loads and the onset of Vortex Induced Vibrations (VIV) under different hydrodynamic actions. The results show that the MAFSL under static conditions is 56m. However, the MAFSLs are 30m and 20m under ordinary weather conditions and hurricane-induced currents for the 100-year return period, respectively, to avoid VIV as cal- culated by using the highest safety class factor. It is suggested that spanning pipelines longer than 20 m should be supported. Addi- tionally, eight successive spans which may also threaten the pipeline were proposed. The most hazardous scour pits are along the pipeline section from KP42 to KP51.展开更多
In maritime safety research,risk is assessed usually within the framework of formal safety assessment(FSA),which provides a formal and systematic methodology to improve the safety of lives,assets,and the environment.A...In maritime safety research,risk is assessed usually within the framework of formal safety assessment(FSA),which provides a formal and systematic methodology to improve the safety of lives,assets,and the environment.A bespoke application of FSA to mitigate accidents in marine seismic surveying is put forward in this paper,with the aim of improving the safety of seismic vessel operations,within the context of developing an economically viable strategy.The work herein takes a close look at the hazards in North Sea offshore seismic surveying,in order to identify critical risk factors,leading to marine seismic survey accidents.The risk factors leading to undesirable events are analysed both qualitatively and quantitatively.A risk matrix is introduced to screen the identified undesirable events.Further to the screening,Fault Tree Analysis(FTA)is presented to investigate and analyse the most critical risks of seismic survey operation,taking into account the lack of historical data.The obtained results show that man overboard(MOB)event is a major risk factor in marine seismic survey operation;lack of training on safe work practice,slippery deck as a result of rain,snow or water splash,sea state affecting human judgement,and poor communication are identified as the critical risk contributors to the MOB event.Consequently,the risk control options are focused on the critical risk contributors for decision-making.Lastly,suggestions for the introduction and development of the FSA methodology are highlighted for safer marine and offshore operations in general.展开更多
Based on the integration analysis of goods and shortcomings of various methods used in safety assessment of coal mines, combining nonlinear feature of mine safety sub-system, this paper establishes the neural network ...Based on the integration analysis of goods and shortcomings of various methods used in safety assessment of coal mines, combining nonlinear feature of mine safety sub-system, this paper establishes the neural network assessment model of mine safety, analyzes the ability of artificial neural network to evaluate mine safety state, and lays the theoretical foundation of artificial neural network using in the systematic optimi- zation of mine safety assessment and getting reasonable accurate safety assessment result.展开更多
Autonomous aerial refueling(AAR)has demonstrated significant benefits to aviation by extending the aircraft range and endurance.It is of significance to assess system safety for autonomous aerial refueling.In this pap...Autonomous aerial refueling(AAR)has demonstrated significant benefits to aviation by extending the aircraft range and endurance.It is of significance to assess system safety for autonomous aerial refueling.In this paper,the reachability analysis method is adopted to assess system safety.Due to system uncertainties,the aerial refueling system can be considered as a stochastic system.Thus,probabilistic reachability is considered.Since there is a close relationship between reachability probability and collision probability,the collision probability of the AAR system is analyzed by using reachability analysis techniques.Then,the collision probability is accessed by using the Monte-Carlo experiment method.Finally,simulations demonstrate the effectiveness of the proposed safety assessment method.展开更多
The construction of waste rock dumps on existing tailing ponds has been put into practice in China to save precious land resources. This work focuses on the safety assessment of the Daheishan molybdenum mine waste roc...The construction of waste rock dumps on existing tailing ponds has been put into practice in China to save precious land resources. This work focuses on the safety assessment of the Daheishan molybdenum mine waste rock dump under construction on two adjoining tailings ponds. The consolidation of the tailings foundation and the filling quality of the waste rock are investigated by the transient electromagnetic method through detecting water-rich areas and loose packing areas, from which, the depth of phreatic line is also estimated. With such information and the material parameters, the numerical method based on shear strength reduction is applied to analyzing the overall stability of the waste rock dump and the tailings ponds over a number of typical cross sections under both current and designed conditions, where the complex geological profiles exposed by site investigation are considered. Through numerical experiments, the influence of soft lenses in the tailings and possible loose packing areas in the waste rock is examined. Although large displacements may develop due to the soft tailings foundation, the results show that the waste rock dump satisfies the safety requirements under both present and designed conditions.展开更多
Human Reliability Analysis(HRA)is an important part in safety assessment of a large complex system.Human Cognitive Reliability(HCR)model is a method of evaluating the probability that operators fail to complete during...Human Reliability Analysis(HRA)is an important part in safety assessment of a large complex system.Human Cognitive Reliability(HCR)model is a method of evaluating the probability that operators fail to complete during diagnostic decision making within a limited time,which is widely used in HRA.In the application of this method,cognitive patterns of humans are required to be considered and classified,and this process often relies on the evaluation opinions of experts which is highly subjective and uncertain.How to effectively express and process this uncertain and subjective information plays a critical role in improving the accuracy and applicability of HCR.In this paper,a new model was proposed to deal with the uncertain information which exists in the processes of cognitive pattern classification in HCR.First,an evaluation panel was constructed based on expert opinions and processing including setting corresponding anchor points and qualitative indicators of different cognitive patterns,and mapping them to fuzzy numbers and unit intervals.Second,based on the evaluation panel,different analysts judge the cognitive pattern types of actual specific events and provide the level of confidence he or she has in the judgments.Finally,the evaluation opinions of multiple analysts were expressed and fused based on the Dempster-Shafer Evidence Theory(DSET),and the fused results were applied to the HCR model to obtain the Human Error Probability(HEP).A case study was used to demonstrate the procedure and effectiveness of the proposed method.展开更多
The European Structural Integrity Assessment Procedure(SINTAP) was applied to the assessment of welded joints of the API 5L X65 pipeline steel with an assumed embedded flaw and surface flaw at the weld toe. At defau...The European Structural Integrity Assessment Procedure(SINTAP) was applied to the assessment of welded joints of the API 5L X65 pipeline steel with an assumed embedded flaw and surface flaw at the weld toe. At default level( level 0), the assessment point was established by esti- mating fracture toughness value K1c conservatively from Charpy energy test data. At the same time, the analysis level 1 (basic level)was applied based on the fracture toughness CTOD. Then the two assessment levels were compared. The assessment results show that all assessment points are located within the failure lines of analysis levels 0 and 1. So the welded joint of the pipeline is safe. It can be concluded that the assessment based on Charpy absorbed energy is practicable when other fracture toughness data are not available, or cannot be easily obtained. The results are conservative.展开更多
To ensure that limited resources are allocated more effectively to reduce marine risks, formal safety assessment (FSA), a proactive method, is introduced in planning a vessel traffic system (VTS). Based on the data of...To ensure that limited resources are allocated more effectively to reduce marine risks, formal safety assessment (FSA), a proactive method, is introduced in planning a vessel traffic system (VTS). Based on the data of Wuhan port, some new solutions based on risk-indices are put forward. The weighted number of traffic accidents is predicted after the future weighted vessel traffic volume is estimated by analyzing the trend of trade development. To analyze risk acceptability, the as-low-as-reasonably-practicable (ALARP) matrix is transformed into a new model containing two parameters: the future weighted vessel traffic volume and the future weighted number of traffic accidents. The new risk control options (RCOs)can be identified by a revised Domino model with several feedback loops from all system levels to close a limited window of accident opportunity. The results indicate that the four most beneficial RCOs are a wider sub-area 1 channel, a VTS bridges area, a dredging sub-area 2 main route, and a VTS QSX anchorage to the 3rd bridge. The FSA is a method that is effective in evaluating the rationality, necessity and cost-effectiveness of VTS projects.展开更多
Geotubes are heterogeneous structures composed of filling sand and bag material,and its pemeability characteristics are different from that of flling sand.The uncertainty of geotubes permeability characteristics resul...Geotubes are heterogeneous structures composed of filling sand and bag material,and its pemeability characteristics are different from that of flling sand.The uncertainty of geotubes permeability characteristics results in the failure of seepage analysis of geotube dams,which restricts the safety assessment of the dams.As the basis of the study on the seepage mechanism of the geotubes,the influence of particle grading on pemeability cofficient of flling sand and sand covered with geotextiles were explored by the pemmeability tests of flling sand with different particle grading under the condition of sand covered with or without geotextiles.And the infuence of geotextiles on the permeability coefficient was analyzed by comparing permeability coefficient of sand covered with and without geotextiles.The test results show that the influence of single particle size content on permeability coe ficient is consistent under the condition of sand covered with and without geotextiles.The content of powder,fine,medium and coarse particles is linearly related to their respective permeability cofficients.And the content of powder,fine,medium particles is negatively correlated with their permeability coefficients,while the content of coarse particles is positively correlated with the permeability coefficient.But the pemeability coefficient of sand covered with geotextiles is smaller than that of flling sand under the same conditions.Finally,the parameter d2 50 Cc/Cu was selected as a variable representing the particle grading to fit the empirical formula of permeability coefficient of flling sand and sand covered with geotextiles.展开更多
基金Project(2023YFB4302500)supported by the National Key R&D Program of ChinaProject(52078485)supported by the National Natural Science Foundation of ChinaProjects(2021-Major-16,2021-Special-08)supported by the Science and Technology Research and Development Program Project of China Railway Group Limited。
文摘Running safety assessment and tracking irregularity parametric sensitivity analysis of high-speed maglev train-bridge system are of great concern,especially need perfect refinement models in which all properties can be well characterized based on various stochastic excitations.A three-dimensional refined spatial random vibration analysis model of high-speed maglev train-bridge coupled system is established in this paper,in which multi-source uncertainty excitation can be considered simultaneously,and the probability density evolution method(PDEM)is adopted to reveal the system-specific uncertainty dynamic characteristic.The motion equation of the maglev vehicle model is composed of multi-rigid bodies with a total 210-degrees of freedom for each vehicle,and a refined electromagnetic force-air gap model is used to account for the interaction and coupling effect between the moving train and track beam bridges,which are directly established by using finite element method.The model is proven to be applicable by comparing with Monte Carlo simulation.By applying the proposed stochastic framework to the high maglev line,the random dynamic responses of maglev vehicles running on the bridges are studied for running safety and stability assessment.Moreover,the effects of track irregularity wavelength range under different amplitude and running speeds on the coupled system are investigated.The results show that the augmentation of train speed will move backward the sensitive wavelength interval,and track irregularity amplitude influences the response remarkably in the sensitive interval.
基金This research was supported by the Funding Project of Chinese Central Government Guiding to the Guangxi Local Science and Technology Development(GUIKEZY21195021)the Natural Science Fund for Distinguished Young Scholars of Guangxi Zhuang Autonomous Region of China(2019GXNSFFA245011)+3 种基金the Funding Project of Chinese Central Government Guiding to the Nanning Local Science and Technology Development(20231012)the Funding Projects of Guangxi Key Research and Development Plan(GUIKE AB23075173)the Funding Project of Technological Development from Angel Yeast(Chongzuo)Co.,Ltd.(JS1006020230722019)the Innovation Project of Guangxi Graduate Education(YCBZ2021012).
文摘The application of microorganisms as probiotics is limited due to lack of safety evaluation.Here,a novel multi-stress-tolerant yeast Meyerozyma guilliermondii GXDK6 with aroma-producing properties was identified from marine mangrove microorganisms.Its safety and probiotic properties were assessed in accordance with phenotype and whole-genome sequencing analysis.Results showed that the genes and phenotypic expression of related virulence,antibiotic resistance and retroelement were rarely found.Hyphal morphogenesis genes(SIT4,HOG1,SPA2,ERK1,ICL1,CST20,HSP104,TPS1,and RHO1)and phospholipase secretion gene(VPS4)were annotated.True hyphae and phospholipase were absent.Only one retroelement(Tad1-65_BG)was found.Major biogenic amines(BAs)encoding genes were absent,except for spermidine synthase(JA9_002594),spermine synthase(JA9_004690),and tyrosine decarboxylase(inx).The production of single BAs and total BAs was far below the food-defined thresholds.GXDK6 had no resistance to common antifungal drugs.Virulence enzymes,such as gelatinase,DNase,hemolytic,lecithinase,and thrombin were absent.Acute toxicity test with mice demonstrated that GXDK6 is safe.GXDK6 has a good reproduction ability in the simulation gastrointestinal tract.GXDK6 also has a strong antioxidant ability,β-glucosidase,and inulinase activity.To sum up,GXDK6 is considered as a safe probiotic for human consumption and food fermentation.
基金National Natural Science Foundation of China under Grant Nos.11972379 and 42377184,Hunan 100-Talent PlanNatural Science Foundation of Hunan Province under Grant No.2022JJ10079+1 种基金Hunan High-Level Talent Plan under Grant No.420030004Central South University Research Project under Grant Nos.202045006(Innovation-Driven Project)and 502390001。
文摘Extensive high-speed railway(HSR)network resembled the intricate vascular system of the human body,crisscrossing mainlands.Seismic events,known for their unpredictability,pose a significant threat to both trains and bridges,given the HSR’s extended operational duration.Therefore,ensuring the running safety of train-bridge coupled(TBC)system,primarily composed of simply supported beam bridges,is paramount.Traditional methods like the Monte Carlo method fall short in analyzing this intricate system efficiently.Instead,efficient algorithm like the new point estimate method combined with moment expansion approximation(NPEM-MEA)is applied to study random responses of numerical simulation TBC systems.Validation of the NPEM-MEA’s feasibility is conducted using the Monte Carlo method.Comparative analysis confirms the accuracy and efficiency of the method,with a recommended truncation order of four to six for the NPEM-MEA.Additionally,the influences of seismic magnitude and epicentral distance are discussed based on the random dynamic responses in the TBC system.This methodology not only facilitates seismic safety assessments for TBC systems but also contributes to standard-setting for these systems under earthquake conditions.
基金supported by the National Key Research and Development Program of China(2021YFB1600601)the Joint Funds of the National Natural Science Foundation of China and the Civil Aviation Administration of China(U1933106)+2 种基金the Scientific Research Project of Tianjin Educational Committee(2019KJ134)the Natural Science Foundation of TianjinIntelligent Civil Aviation Program(21JCQNJ C00900)。
文摘To solve the problem of risk identification and quantitative assessment for human-computer interaction(HCI)in complex avionics systems,an HCI safety analysis framework based on system-theoretical process analysis(STPA)and cognitive reliability and error analysis method(CREAM)is proposed.STPACREAM can identify unsafe control actions and find the causal path during the interaction of avionics systems and pilot with the help of formal verification tools automatically.The common performance conditions(CPC)of avionics systems in the aviation environment is established and a quantitative analysis of human failure is carried out.Taking the head-up display(HUD)system interaction process as an example,a case analysis is carried out,the layered safety control structure and formal model of the HUD interaction process are established.For the interactive behavior“Pilots approaching with HUD”,four unsafe control actions and35 causal scenarios are identified and the impact of common performance conditions at different levels on the pilot decision model are analyzed.The results show that HUD's HCI level gradually improves as the scores of CPC increase,and the quality of crew member cooperation and time sufficiency of the task is the key to its HCI.Through case analysis,it is shown that STPACREAM can quantitatively assess the hazards in HCI and identify the key factors that impact safety.
文摘This article presents a real-life project that aimed to evaluate the safety of traffic vehicles on old bridges without any prior data.The project involved various safety inspections,including conventional,static,and dynamic load inspections and safety assessments.After conducting these tests,it was concluded that the structure of the old bridge is relatively safe,with only a few bumps.The bridge could function normally following appropriate treatment.The analysis provides valuable insights into the assessment of the quality and safety of such bridges to ensure the safe driving of heavy vehicles.
基金the National Natural Science Foundation of China(52105070,U21B2074)Department of Science and Technology of Liaoning Province China(2033JH1/10400007).
文摘In the field of model-based system assessment,mathematical models are used to interpret the system behaviors.However,the industrial systems in this intelligent era will be more manageable.Various management operations will be dynamically set,and the system will be no longer static as it is initially designed.Thus,the static model generated by the traditional model-based safety assessment(MBSA)approach cannot be used to accurately assess the dependability.There mainly exists three problems.Complex:huge and complex behaviors make the modeling to be trivial manual;Dynamic:though there are thousands of states and transitions,the previous model must be resubmitted to assess whenever new management arrives;Unreusable:as for different systems,the model must be resubmitted by reconsidering both the management and the system itself at the same time though the management is the same.Motivated by solving the above problems,this research studies a formal management specifying approach with the advantages of agility modeling,dynamic modeling,and specification design that can be re-suable.Finally,three typical managements are specified in a series-parallel system as a demonstration to show the potential.
文摘Road transport safety policies have emphasized road infrastructure safety design and engineering as a core function.However,in developing countries like Vietnam,this approach has been slower to adopt,resulting in substandard roads.In-depth studies of accident locations indicate that road environment factors contribute significantly to road accidents in Vietnam and road design features are associated with specific accident types and hazards.Proactive and reactive approaches,such as road safety audit,inspection,assessment,and treatment of hazardous locations,are necessary to ensure that the road and its environment are safe.This paper provides an overview of road safety in Vietnam in general,and Ho Chi Minh in particular,including its factors and characteristics,as well as road infrastructure safety improvements.The iRap tool for road safety inspection and assessment is highlighted as a potential method for systematically analyzing road infrastructure deficiencies and providing targeted countermeasures to improve road safety under mixed traffic conditions.
基金Supported by the National High Technology Research and Development Program of China("863"Program)(2006AA12A105)~~
文摘A new safety assessment method for parallel routes is presented. From the aspects of safety guard system of air traffic control(ATC) and considering the flight conflict as causing event of air collision accidents, this paper fosters a four-layer safety guard of controller command, short-term conflict alerts (STCAs), pilot visual avoidance, and traffic alert collision avoidance system(TCAS). Then, the problem of parallel routes collision risk is divided into two parts:the calculation of potential flight conflict and the analysis of failure probability of the four-layer safety guard. A calculation model for controller interference times is induced. By using cognitive reliability and error analysis method(CREAM),the calculation problem to failure probability of controller sequencing flight conflicts is solved and a fault tree model of guard failure of STCA and TCAS is established. Finally, the Beijing-Shanghai parallel routes are taken as an example to be calculated and the collision risk of the parallel routes is obtained under the condition of radar control. Results show that the parallel routes can satisfy the safety demands.
基金supported by the National Natural Science Foundation of China(Nos.U1564206,U1764258)the National Key R&D Program of China(No.2018YFB0105700)+1 种基金the support from China Scholarship Council(No.201806030115)supported by the Department of Energy(DOE),Office of Electricity(OE)at Oak Ridge National Laboratory managed by UL-Battelle LLC under contract DE-AC05-00OR22725。
文摘In this paper,overcharge behaviors and thermal runaway(TR)features of large format lithium-ion(Liion)cells with different cathode materials(LiFePO4(LFP),Li[Ni_(1/3)Co_(1/3)Mn_(1/3)]O_(2)(NCM111),Li[Ni_(0.6)Co_(0.2)Mn_(0.2)]O_(2)(NCM622)and Li[Ni_(0.8)Co_(0.1)Mn_(0.1)]O_(2)(NCM811))were investigated.The results showed that,under the same overcharge condition,the TR of LFP Li-ion cell occurred earlier compared with the NCM Li-ion cells,indicating its poor overcharge tolerance and high TR risk.However,when TR occurred,LFP Li-ion cell exhibited lower maximum temperature and mild TR response.All NCM Liion cells caught fire or exploded during TR,while the LFP Li-ion cell only released a large amount of smoke without fire.According to the overcharge behaviors and TR features,a safety assessment score system was proposed to evaluate the safety of the cells.In short,NCM Li-ion cells have better performance in energy density and overcharge tolerance(or low TR risk),while LFP Li-ion cell showed less severe response to overcharging(or less TR hazards).For NCM Li-ion cells,as the ratio of nickel in cathode material increases,the thermal stability of the cathode materials becomes poorer,and the TR hazards increase.Such a comparison study on large format Li-ion cells with different cathode materials can provide deeper insights into the overcharge behaviors and TR features,and provide guidance for engineers to reasonably choose battery materials in automotive applications.
基金supported in part by the National Natural Science Foundation of China(61833016,61751304,61873273,61702142,61773388)the Key Research and Development Plan of Hainan(ZDYF2019007)Shaanxi Outstanding Youth Science Foundation(2020JC-34)。
文摘Safety assessment is one of important aspects in health management.In safety assessment for practical systems,three problems exist:lack of observation information,high system complexity and environment interference.Belief rule base with attribute reliability(BRB-r)is an expert system that provides a useful way for dealing with these three problems.In BRB-r,once the input information is unreliable,the reliability of belief rule is influenced,which further influences the accuracy of its output belief degree.On the other hand,when many system characteristics exist,the belief rule combination will explode in BRB-r,and the BRB-r based safety assessment model becomes too complicated to be applied.Thus,in this paper,to balance the complexity and accuracy of the safety assessment model,a new safety assessment model based on BRB-r with considering belief rule reliability is developed for the first time.In the developed model,a new calculation method of the belief rule reliability is proposed with considering both attribute reliability and global ignorance.Moreover,to reduce the influence of uncertainty of expert knowledge,an optimization model for the developed safety assessment model is constructed.A case study of safety assessment of liquefied natural gas(LNG)storage tank is conducted to illustrate the effectiveness of the new developed model.
基金the National Natural Science Foundation of China (505079047)
文摘Safety assessment of offshore platforms is an urgent task. Such assessments are now focusing on the structure, maintenance, and retirement of a platform. Some methods employed have many shortcomings. For example, they cannot make the reliability adequately explicable. Therefore, a mathematical tool, the unascertained measure, was introduced. First, the basic knowledge of the unascertained sets was introduced briefly. Second, the unascertained measure was defined and credible identification was set up. The method has been introduced into the fields for safety assessment of a jacket loadout procedure. Engineering practices showed that it can complete the safety assessment systematically and scientifically without any assumption. The work should have significance in theory and practice for offshore engineering.
基金supported by the National Basic Research Program of China (973 Program) (Grant No.2005CB422304)the Ocean University of China Scientific Research Start-up Funds Project for Introduced Talents
文摘The DFI-1 submarine pipeline was investigated using a dual-frequency side-scan sonar and a swath sounder system. More than a hundred scour pits under the pipeline were found, most of which have caused the span of the pipeline to increase and threatened its safety. The maximum allowable free span length (MAFSL) of the pipeline was determined through the limitations re- garding maximum allowable stress under static or quasi-static loads and the onset of Vortex Induced Vibrations (VIV) under different hydrodynamic actions. The results show that the MAFSL under static conditions is 56m. However, the MAFSLs are 30m and 20m under ordinary weather conditions and hurricane-induced currents for the 100-year return period, respectively, to avoid VIV as cal- culated by using the highest safety class factor. It is suggested that spanning pipelines longer than 20 m should be supported. Addi- tionally, eight successive spans which may also threaten the pipeline were proposed. The most hazardous scour pits are along the pipeline section from KP42 to KP51.
基金This project"Formal Safety Assessment of a Marine Seismic Survey Vessel Operation,Incorporating Risk Matrix and Fault Tree Analysis"has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 730888.
文摘In maritime safety research,risk is assessed usually within the framework of formal safety assessment(FSA),which provides a formal and systematic methodology to improve the safety of lives,assets,and the environment.A bespoke application of FSA to mitigate accidents in marine seismic surveying is put forward in this paper,with the aim of improving the safety of seismic vessel operations,within the context of developing an economically viable strategy.The work herein takes a close look at the hazards in North Sea offshore seismic surveying,in order to identify critical risk factors,leading to marine seismic survey accidents.The risk factors leading to undesirable events are analysed both qualitatively and quantitatively.A risk matrix is introduced to screen the identified undesirable events.Further to the screening,Fault Tree Analysis(FTA)is presented to investigate and analyse the most critical risks of seismic survey operation,taking into account the lack of historical data.The obtained results show that man overboard(MOB)event is a major risk factor in marine seismic survey operation;lack of training on safe work practice,slippery deck as a result of rain,snow or water splash,sea state affecting human judgement,and poor communication are identified as the critical risk contributors to the MOB event.Consequently,the risk control options are focused on the critical risk contributors for decision-making.Lastly,suggestions for the introduction and development of the FSA methodology are highlighted for safer marine and offshore operations in general.
基金Supported by the National Natural Science Foundation of China(50274060) and State Administration of Work Safety(03-103)
文摘Based on the integration analysis of goods and shortcomings of various methods used in safety assessment of coal mines, combining nonlinear feature of mine safety sub-system, this paper establishes the neural network assessment model of mine safety, analyzes the ability of artificial neural network to evaluate mine safety state, and lays the theoretical foundation of artificial neural network using in the systematic optimi- zation of mine safety assessment and getting reasonable accurate safety assessment result.
基金This work was supported by the National Natural Science Foundation of China(No.61933010).
文摘Autonomous aerial refueling(AAR)has demonstrated significant benefits to aviation by extending the aircraft range and endurance.It is of significance to assess system safety for autonomous aerial refueling.In this paper,the reachability analysis method is adopted to assess system safety.Due to system uncertainties,the aerial refueling system can be considered as a stochastic system.Thus,probabilistic reachability is considered.Since there is a close relationship between reachability probability and collision probability,the collision probability of the AAR system is analyzed by using reachability analysis techniques.Then,the collision probability is accessed by using the Monte-Carlo experiment method.Finally,simulations demonstrate the effectiveness of the proposed safety assessment method.
基金Projects(51209118,71373245)supported by the National Natural Science Foundation of ChinaProject(2014JBKY01)supported by the Fundamental Research Funds for CASST,China
文摘The construction of waste rock dumps on existing tailing ponds has been put into practice in China to save precious land resources. This work focuses on the safety assessment of the Daheishan molybdenum mine waste rock dump under construction on two adjoining tailings ponds. The consolidation of the tailings foundation and the filling quality of the waste rock are investigated by the transient electromagnetic method through detecting water-rich areas and loose packing areas, from which, the depth of phreatic line is also estimated. With such information and the material parameters, the numerical method based on shear strength reduction is applied to analyzing the overall stability of the waste rock dump and the tailings ponds over a number of typical cross sections under both current and designed conditions, where the complex geological profiles exposed by site investigation are considered. Through numerical experiments, the influence of soft lenses in the tailings and possible loose packing areas in the waste rock is examined. Although large displacements may develop due to the soft tailings foundation, the results show that the waste rock dump satisfies the safety requirements under both present and designed conditions.
基金supported by Shanghai Natural Science Foundation(Grant No.19ZR1420700)sponsored by Shanghai Rising-Star Program(Grant No.21QA1403400)Shanghai Key Laboratory of Power Station Automation Technology(Grant No.13DZ2273800).
文摘Human Reliability Analysis(HRA)is an important part in safety assessment of a large complex system.Human Cognitive Reliability(HCR)model is a method of evaluating the probability that operators fail to complete during diagnostic decision making within a limited time,which is widely used in HRA.In the application of this method,cognitive patterns of humans are required to be considered and classified,and this process often relies on the evaluation opinions of experts which is highly subjective and uncertain.How to effectively express and process this uncertain and subjective information plays a critical role in improving the accuracy and applicability of HCR.In this paper,a new model was proposed to deal with the uncertain information which exists in the processes of cognitive pattern classification in HCR.First,an evaluation panel was constructed based on expert opinions and processing including setting corresponding anchor points and qualitative indicators of different cognitive patterns,and mapping them to fuzzy numbers and unit intervals.Second,based on the evaluation panel,different analysts judge the cognitive pattern types of actual specific events and provide the level of confidence he or she has in the judgments.Finally,the evaluation opinions of multiple analysts were expressed and fused based on the Dempster-Shafer Evidence Theory(DSET),and the fused results were applied to the HCR model to obtain the Human Error Probability(HEP).A case study was used to demonstrate the procedure and effectiveness of the proposed method.
基金Supported by National Natural Science Foundation of China(No. 50375109)
文摘The European Structural Integrity Assessment Procedure(SINTAP) was applied to the assessment of welded joints of the API 5L X65 pipeline steel with an assumed embedded flaw and surface flaw at the weld toe. At default level( level 0), the assessment point was established by esti- mating fracture toughness value K1c conservatively from Charpy energy test data. At the same time, the analysis level 1 (basic level)was applied based on the fracture toughness CTOD. Then the two assessment levels were compared. The assessment results show that all assessment points are located within the failure lines of analysis levels 0 and 1. So the welded joint of the pipeline is safe. It can be concluded that the assessment based on Charpy absorbed energy is practicable when other fracture toughness data are not available, or cannot be easily obtained. The results are conservative.
基金Shanghai Pujiang Program,the Program of Shanghai Municipal Education Commission (No.07ZZ103)
文摘To ensure that limited resources are allocated more effectively to reduce marine risks, formal safety assessment (FSA), a proactive method, is introduced in planning a vessel traffic system (VTS). Based on the data of Wuhan port, some new solutions based on risk-indices are put forward. The weighted number of traffic accidents is predicted after the future weighted vessel traffic volume is estimated by analyzing the trend of trade development. To analyze risk acceptability, the as-low-as-reasonably-practicable (ALARP) matrix is transformed into a new model containing two parameters: the future weighted vessel traffic volume and the future weighted number of traffic accidents. The new risk control options (RCOs)can be identified by a revised Domino model with several feedback loops from all system levels to close a limited window of accident opportunity. The results indicate that the four most beneficial RCOs are a wider sub-area 1 channel, a VTS bridges area, a dredging sub-area 2 main route, and a VTS QSX anchorage to the 3rd bridge. The FSA is a method that is effective in evaluating the rationality, necessity and cost-effectiveness of VTS projects.
基金The author(s)received funding for this study from Key Research Project of Natural Science in Colleges and Universities of Anhui Province(KJ2019A0640)and(KJ2018B09).
文摘Geotubes are heterogeneous structures composed of filling sand and bag material,and its pemeability characteristics are different from that of flling sand.The uncertainty of geotubes permeability characteristics results in the failure of seepage analysis of geotube dams,which restricts the safety assessment of the dams.As the basis of the study on the seepage mechanism of the geotubes,the influence of particle grading on pemeability cofficient of flling sand and sand covered with geotextiles were explored by the pemmeability tests of flling sand with different particle grading under the condition of sand covered with or without geotextiles.And the infuence of geotextiles on the permeability coefficient was analyzed by comparing permeability coefficient of sand covered with and without geotextiles.The test results show that the influence of single particle size content on permeability coe ficient is consistent under the condition of sand covered with and without geotextiles.The content of powder,fine,medium and coarse particles is linearly related to their respective permeability cofficients.And the content of powder,fine,medium particles is negatively correlated with their permeability coefficients,while the content of coarse particles is positively correlated with the permeability coefficient.But the pemeability coefficient of sand covered with geotextiles is smaller than that of flling sand under the same conditions.Finally,the parameter d2 50 Cc/Cu was selected as a variable representing the particle grading to fit the empirical formula of permeability coefficient of flling sand and sand covered with geotextiles.