A genuine technological issue–the thermal convection of liquid in a rotating cavity–is investigated experimentally.The experiments are conducted within a horizontal annulus with isothermal boundaries. The inner boun...A genuine technological issue–the thermal convection of liquid in a rotating cavity–is investigated experimentally.The experiments are conducted within a horizontal annulus with isothermal boundaries. The inner boundaryof the annulus has a higher temperature, thus exerting a stabilising influence on the system. It is shown that whenthe layer rotation velocity diminishes, two-dimensional azimuthally periodic convective rolls, rotating togetherwith the cavity, emerge in a threshold manner. The development of convection is accompanied by a significantintensification of heat transfer through the layer. It is shown that the averaged thermal convection excitation inthe form of a system of two-dimensional rolls occurs against the background of oscillations of a non-isothermalfluid in the cavity reference frame caused by the gravity field. The excitation threshold and the structure ofconvective rolls are consistent with the results of the earlier theoretical studies by the authors performed usingthe equations of “vibrational” convection obtained by the averaging method. Furthermore, the experiments haverevealed a new type of averaged flow in the form of a spatially periodic system of toroidal vortices. It is shown thata steady streaming, excited by the inertial oscillations of the fluid, is responsible for the generation of the toroidalvortices. These flows develop in a non-threshold manner and are most clearly manifested in a case of resonantexcitation of one of the inertial modes.展开更多
A comprehensive mathematical model of annulus-electromagnetic direct chill (A-EMDC) casting of A357 aluminum alloy was established with corresponding experimental verification. The model was based on a combination o...A comprehensive mathematical model of annulus-electromagnetic direct chill (A-EMDC) casting of A357 aluminum alloy was established with corresponding experimental verification. The model was based on a combination of the commercial finite element package ANSYS and the commercial finite volume package FLUENT. The effects of structural parameters on fluid flow, temperature field and solidification during A-EMDC process were investigated numerically. The results show that structural parameters such as annulus gap width, annulus gap position, and centre pipe length influence the flow and temperature fields. The smaller the annulus gap width is, the more uniform the temperature is, and the smaller the temperature gradient is. With increasing the centre pipe length, the circular flow would decrease due to the dislocation of centre pipe. Specially, when the annulus gap is located at periphery of the billet, the temperature gradient of the longitudinal direction in the solidification region falls evidently.展开更多
AIM To apply real time three-dimensional transesophageal echocardiography(RT3D TEE) for quantitative and qualitative assessment of the mitral valve annulus(MVA) and tricuspid valve annulus(TVA) in the same patient.MET...AIM To apply real time three-dimensional transesophageal echocardiography(RT3D TEE) for quantitative and qualitative assessment of the mitral valve annulus(MVA) and tricuspid valve annulus(TVA) in the same patient.METHODS Our retrospective cohort study examined the MVA and TVA in 49 patients by RT3 D TEE. MVA and TVA shape were examined by TEE. The MVA and TVA volume data set images were acquired in the mid esophageal 4-chamber view. The MVA and TVA were acquired separately, with optimization of each for the highest frame rate and image quality. The 3D shape of the annuli was reconstructed using the Philips~? Q lab, MVQ ver. 6.0 MVA model software. The end-systolic frame was used. The parameters measured and compared were annular area, circumference, high-low distances(height), anterolateralposterolateral(ALPM), and anteroposterior(AP) axes. RESULTS A total of 49 patients(mean age 61 ± 14 years, 45% males) were studied. The ALPM and the AP axes of the MVA and TVA are not significantly different. The ALPM axis of the MVA was 37.9 ± 6.4 mm and 38.0 ± 5.6 mm for the TVA(P = 0.70). The AP axis of the MVA was 34.8 ± 5.7 mm and 34.9 ± 6.2 mm for the TVA(P = 0.90). The MVA and the TVA had similar circumference and area. The circumference of the MVA was 127.9 ± 16.8 mm and 125.92 ± 16.12 mm for the TVA(P = 0.23). The area of the MVA was 1103.7 ± 307.8 mm^2 and 1131.7 ± 302.0 mm^2 for the TVA(P = 0.41). The MVA and TVA are similar oval structures, but with significantly different heights. The ALPM/AP ratio for the MVA was 1.08 ± 0.33 and 1.09 ± 0.28 for the TVA(P < 0.001). The height for the MVA and TVA was 9.23 ± 2.11 mm and 4.37 ± 1.48 mm, respectively(P < 0.0001). CONCLUSION RT3 D TEE plays an unprecedented role in the management of valvular heart disease. The specific and exclusive shape of the MVA and TVA was revealed in our study of patients studied. Moreover, the intricate codependence of the MVA and the TVA depends on their distinctive shapes. This realization seen from our study will allow us to better understand the role valvular disease plays in disease states such as hypertrophic cardiomyopathy and pulmonary hypertension.展开更多
Annulus fibrosus (AF) tissue engineering has recently received increasing attention as a treatment for intervertebral disc 0VD) degeneration; however, such engineering remains challenging because of the remarkable ...Annulus fibrosus (AF) tissue engineering has recently received increasing attention as a treatment for intervertebral disc 0VD) degeneration; however, such engineering remains challenging because of the remarkable complexity of AF tissue. In order to engineer a functional AF replacement, the fabrication of cell-scaffold constructs that mimic the cellular, biochemical and structural features of native AF tissue is critical. In this study, we fabricated aligned fibroua polyurethane scaffolds using an electrospinning technique and used them for culturing AF-derived-stem/progenitor cells (AFSCs). Random fibrous scaffolds, also prepared via electrospinningy were used as a control. We compared the morphology, proliferation, gene expression and matrix production of AFSCs on aligned scaffolds and random scaffolds. There was no apparent difference in the attachment or proliferation of cells cultured on aligned scaffolds and random scaffolds. However, compared to cells on random scaffolds, the AFSCs on aligned scaffolds were more elongated and better aligned, and they exhibited higher gene expression and matrix production of coUagen-I and aggrecan. The gene expression and protein production of coUagen-II did not appear to differ between the two groups. Together, these findings indicate that aligned fibrous scaffolds may provide a favourable microenvironment for the differentiation of AFSCs into cells similar to outer AF cells, which predominantly produce collagen-I matrix.展开更多
Miniaturization of electronic equipment has forced researchers to devise more effective methods for dissipating the generated heat in these devices.In this study,two methods,including porous media inserting and adding...Miniaturization of electronic equipment has forced researchers to devise more effective methods for dissipating the generated heat in these devices.In this study,two methods,including porous media inserting and adding nanoparticles to the base fluid,are used to improve heat transfer in an annulus heated on both walls.To study porous media insert,porous ribs are used on the outer and inner walls independently.The results show that when porous ribs are placed on the outer wall,although the heat transfer enhances,the pressure drop increment is so considerable that performance number (the ratio of heat transfer enhancement pressure increment,PN) is less than unity for all porous rib heights and porous media permeabilities that are studied.On the other hand,the PN of cases where porous ribs were placed on the inner wall depends on the Darcy number (Da).For example,for ribs with Da=0.1 and Da=0.0001,the maximum performance number,PN=4,occurs at the porous ribs height to hydraulic diameter ratios H/Dh=1 and H/Dh=0.25.Under these conditions,heat transfer is enhanced by two orders of magnitude.It is found that adding 5% nanoparticles to the base fluid in the two aforementioned cases improves the Nusselt number and PN by 10%–40%.展开更多
Stress corrosion cracking (SCC) behavior of P 110 tubing steel in simulated C02 injection well annulus environments was investigated through three-point bent tests, potentiodynamic polarization and EIS measurements....Stress corrosion cracking (SCC) behavior of P 110 tubing steel in simulated C02 injection well annulus environments was investigated through three-point bent tests, potentiodynamic polarization and EIS measurements. The results demonstrate that SCC of P110 tubing steel could occur in acidulous simulated environment, and the sensitivity of SCC increases with the decrease ofpH, as well as increase of sulfide concentration and total environmental pressure. Both anodic dissolution and hydrogen embrittlement make contributions to the SCC. Adequate concentration of corrosion inhibitor can inhibit the occurrence of SCC on account of the inhibition of localized anodic dissolution and cathodic hydrogen evolution.展开更多
The present work relates to a numerical investigation of double diffusive mixed convection around a horizontal annulus with a finned inner cylinder.The solutal and thermal buoyancy forces are sustained by maintaining ...The present work relates to a numerical investigation of double diffusive mixed convection around a horizontal annulus with a finned inner cylinder.The solutal and thermal buoyancy forces are sustained by maintaining the inner and outer cylinders at uniform temperatures and concentrations.Buoyancy effects are also considered,with the Boussinesq approximation.The forced convection effect is induced by the outer cylinder rotating with an angular velocity(ω)in an anti-clockwise direction.The studies are made for various combinations of dimensionless numbers;buoyancy ratio number(N),Lewis number(Le),Richardson number(Ri)and Grashof number(Gr).The isotherms,isoconcentrations and streamlines as well as both average and local Nusselt and Sherwood numbers were studied.A finite volume scheme is adopted to solve the transport equations for continuity,momentum,energy and mass transfer.The results indicate that the use of fins on the inner cylinder with outer cylinder rotation,significantly improves the heat and mass transfer in the annulus.展开更多
In order to investigate the apoptotic pathway of rabbit annulus fibrosus(AF) cells induced by mechanical overload,an experimental air-pressure model was established in this study to pressurize the rabbit AF cells in v...In order to investigate the apoptotic pathway of rabbit annulus fibrosus(AF) cells induced by mechanical overload,an experimental air-pressure model was established in this study to pressurize the rabbit AF cells in vitro.Cells were randomly divided into five groups in which the cells were exposed to a continuous pressure of 1.1 MPa for different lengths of time(0,5,12,24 and 36 h).The cell proliferation and apoptosis were detected by cell counting kit-8(CCK-8) assay and flow cytometry;the alterations in mitochondrial membrane potential were measured by fluorescence microscopy and fluorescence spectrophotometer;the activities of caspase-8 and 9 were determined by spectrophotometry.The results showed that after the cells were subjected to the pressure for 24 or 36 h,the cell proliferation was inhibited;the ratio of cell apoptosis was increased;the mitochondrial membrane potential was decreased;the activity of caspase-9 was enhanced;no activity changes were observed in caspase-8.The results suggested that treatment with a pressure of 1.1 MPa for more than 24 h can lead to the proliferation inhibition and the apoptosis of rabbit AF cells in vitro,and the mitochondrial-dependent pathway is implicated in the pressure-induced AF cell apoptosis.展开更多
Heat transfer and entropy generation of developing laminar forced convection flow of water-Al_2O_3 nanofluid in a concentric annulus with constant heat flux on the walls is investigated numerically. In order to determ...Heat transfer and entropy generation of developing laminar forced convection flow of water-Al_2O_3 nanofluid in a concentric annulus with constant heat flux on the walls is investigated numerically. In order to determine entropy generation of fully developed flow, two approaches are employed and it is shown that only one of these methods can provide appropriate results for flow inside annuli. The effects of concentration of nanoparticles, Reynolds number and thermal boundaries on heat transfer enhancement and entropy generation of developing laminar flow inside annuli with different radius ratios and same cross sectional areas are studied. The results show that radius ratio is a very important decision parameter of an annular heat exchanger such that in each Re, there is an optimum radius ratio to maximize Nu and minimize entropy generation. Moreover, the effect of nanoparticles concentration on heat transfer enhancement and minimizing entropy generation is stronger at higher Reynolds.展开更多
The convective heat transfer of hybrid nanoliquids within a concentric annulus has wide engineering applications such as chemical industries, solar collectors, gas turbines, heat exchangers, nuclear reactors, and elec...The convective heat transfer of hybrid nanoliquids within a concentric annulus has wide engineering applications such as chemical industries, solar collectors, gas turbines, heat exchangers, nuclear reactors, and electronic component cooling due to their high heat transport rate. Hence, in this study, the characteristics of the heat transport mechanism in an annulus filled with the Ag-MgO/H_2O hybrid nanoliquid under the influence of quadratic thermal radiation and quadratic convection are analyzed. The nonuniform heat source/sink and induced magnetic field mechanisms are used to govern the basic equations concerning the transport of the composite nanoliquid. The dependency of the Nusselt number on the effective parameters(thermal radiation, nonlinear convection,and temperature-dependent heat source/sink parameter) is examined through sensitivity analyses based on the response surface methodology(RSM) and the face-centered central composite design(CCD). The heat transport of the composite nanoliquid for the spacerelated heat source/sink is observed to be higher than that for the temperature-related heat source/sink. The mechanisms of quadratic convection and quadratic thermal radiation are favorable for the momentum of the nanoliquid. The heat transport rate is more sensitive towards quadratic thermal radiation.展开更多
The existence of radial solutions of Δu + λg(|x|)f(u) = 0 in annuli with Dirichlet(Dirichlet/Neumann) boundary conditions is investigated.It is proved that the problems have at least two positive radial sol...The existence of radial solutions of Δu + λg(|x|)f(u) = 0 in annuli with Dirichlet(Dirichlet/Neumann) boundary conditions is investigated.It is proved that the problems have at least two positive radial solutions on any annulus if f is superlinear at 0 and sublinear at ∞.展开更多
Improving the closure effect of surgical suture for repair of annulus fibrosus defects remains an unsolved problem.A new type of porcine fibrin glue was reported for the repair of annulus fibrous defects in sheep mode...Improving the closure effect of surgical suture for repair of annulus fibrosus defects remains an unsolved problem.A new type of porcine fibrin glue was reported for the repair of annulus fibrous defects in sheep models in this study.Continuous axial loading test showed that this glue could effectively improve the closure effect of surgical suture for annulus fibrous defect.Magnetic resonance imaging (MRI) of the lumbar spine confirmed that,compared with nonfibrin glue treated intervertebral discs,it contributed to preservation of the nucleus pulposus and maintained the physiological hydration of the intervertebral discs.Moreover,histomorphology evaluation showed that the porcine fibrin glue could partially reverse degeneration of the injured intervertebral discs.Taken together,porcine fibrin glue can effectively enhance the closure effect of surgical suture on annulus fibrosus,improve the repair effect and slow down the degeneration of the intervertebral disc,and provide a potential therapeutic strategy for degenerative intervertebral disc disease.展开更多
In this study, integral operational methods are used to investigate the thermally induced transverse vibration of a thin elliptic annulus plate with elastic supports at both radial boundaries.The axisymmetric temperat...In this study, integral operational methods are used to investigate the thermally induced transverse vibration of a thin elliptic annulus plate with elastic supports at both radial boundaries.The axisymmetric temperature distribution is determined by the heat conduction differential equation and its corresponding boundary conditions by employing a unified integral transform technique by use of Mathieu functions and modified Mathieu functions. The solution of thermally induced vibration of the plate with both ends encased with elastic supports is obtained by employing an integral transform for double Laplace differential equation. The thermal moment is derived on the basis of temperature distribution, and its stresses are obtained based on resultant bending moments per unit width. The numerical calculations of the distributions of the transient temperature and its associated stress distributions are shown in the figures.展开更多
We report an acoustic focusing lens composed of two-layer annuluses made of metal cylinders in air. We find that the cylindrical waves can be focused into a perfect point without diffraction in the centre of the annul...We report an acoustic focusing lens composed of two-layer annuluses made of metal cylinders in air. We find that the cylindrical waves can be focused into a perfect point without diffraction in the centre of the annuluses, which arises from the Mie-resonance modes in the annuluses. The focusing frequencies are related to the size of the inner annulus, and the focusing effect can be applied to the annuluses with different shapes and incident positions. Interesting applications of the focusing lens in the acoustic beam splitter and directional transmitter with energy enhancement are further discussed.展开更多
Thermophoresis is an important mechanism of micro-particle transport due to temperature gradients in the surrounding medium.It has numerous applications,especially in the field of aerosol technology.This study has num...Thermophoresis is an important mechanism of micro-particle transport due to temperature gradients in the surrounding medium.It has numerous applications,especially in the field of aerosol technology.This study has numerically investigated the thermophoretic deposition efficiency of particles in a laminar gas flow in a concentric annulus using the critical trajectory method.The governing equations are the momentum and energy equations for the gas and the particle equations of motion.The effects of the annulus size,particle diameter,the ratio of inner to outer radius of tube and wall temperature on the deposition efficiency were studied for both developing and fully-developed flows.Simulation results suggest that thermophoretic deposition increases by increasing thermal gradient,deposition distance,and the ratio of inner to outer radius,but decreases with increasing particle size.It has been found that by taking into account the effect of developing flow at the entrance region,higher deposition efficiency was obtained,than fully developed flow.展开更多
In this paper, boiling heat transfer in a vertical annulus with inner side heated with and without air introduction is experimentally studied. Results show that boiling heat transfer is significantly enhanced by the i...In this paper, boiling heat transfer in a vertical annulus with inner side heated with and without air introduction is experimentally studied. Results show that boiling heat transfer is significantly enhanced by the introduction of air. When air is introduced into the liquid with a temperature below boiling point, the enhancement of heat transfer is also detected. It is concluded from the study that the heat transfer enhanced by introduction of inert gas is due to the liquid vaporization at the gas-liquid interface near the wall, which removes a large amount of latent heat and lowers the interfacial temperature considerably. Thus the gas-liquid interface acts as a 'heat sink'and the heat transfer is augmented significantly.展开更多
Hole cleaning is a complex process as there are many variables affecting cuttings removal(e.g.drilling fluid type,density,flow rate and rheological properties,cuttings size,drill pipe rotation speed).With the increasi...Hole cleaning is a complex process as there are many variables affecting cuttings removal(e.g.drilling fluid type,density,flow rate and rheological properties,cuttings size,drill pipe rotation speed).With the increasing number of drilling small diameter wells(e.g.coiled tubing drilling applications,ultra-deep wells drilled for exploitations of unconventional oil and gas resources),the wall resistance of the micro annulus also emerges as one of the most critical factors affecting the cuttings accumulation in wellbore.The eccentricity of drill pipes commonly observed during the drilling process of ultra-deep well and coiled tubing well makes the wall resistance effect on the cuttings transport even more prominent.Understanding the wall resistance effect on the particle settling behavior in eccentric annuli is,therefore,crucial for hydraulic design of efficient cuttings transport operations in these wells.In this study,a total of 196 sets of particle settling experiments were carried out to investigate the particle settling behavior in eccentric annuli filled with power-law fluids.The test matrix included the eccentricity ranges of 0-0.80,the dimensionless diameter ranges of 0.13-0.75 and the particle Reynolds number ranges of 0.09-32.34.A high-speed camera was used to record the particle settling process and determine the influences of the eccentricity,the dimensionless diameter,the fluid rheological properties,and the solid particle characteristics on the wall factor and the particle settling velocity.The functional relationship among the dimensionless diameter,the particle Reynolds number,and the wall factor was determined by using the method of controlling variables.An eccentric annulus wall factor model with average relative error of 5.16%was established.Moreover,by introducing Archimedes number,an explicit model of particle settling velocity in the eccentric annulus with average relative error of 10.17%was established.A sample calculation of particle settling velocity was provided to show the application of the explicit model.Results of this study can be used as a guideline by field engineers to improve hydraulic design of cuttings transport operations in concentric and eccentric annuli.展开更多
A thermoelastic problem of a circular annulus made of functionally graded materials with an arbitrary gradient is investigated. Different from previous works, our analysis neither requires a special form of the gradie...A thermoelastic problem of a circular annulus made of functionally graded materials with an arbitrary gradient is investigated. Different from previous works, our analysis neither requires a special form of the gradient of material properties nor demands partitioning the entire structure into a multilayered homogeneous structure. Instead, we propose a new method for solving the thermoelastic problem of a functionally graded circular annulus by transforming it to a Fredholm integral equation. The distribution of thermal stresses and radial displacement can be obtained by solving the resulting equation. Illustrative examples are given to show the effects of varying gradients on the thermal stresses and radial displacement for given temperature changes at the inner and outer surfaces. The results indicate that the thermal stresses can be relaxed for specified gradients, which is beneficial to design an inhomogeneous annulus to maintain structural integrity.展开更多
Background:The surgical outcomes of tetralogy of Fallot(TOF)have evolved dramatically and have resulted in lower mortality rate.Currently,the many cardiac centers have a trend to early single-stage complete repair mor...Background:The surgical outcomes of tetralogy of Fallot(TOF)have evolved dramatically and have resulted in lower mortality rate.Currently,the many cardiac centers have a trend to early single-stage complete repair more than a staged repair.However,the patients who have an early primary repair were required transannular patch augmentation of a pulmonary valve frequently.This effect has been developed a chronic pulmonary insufficiency may lead to right ventricular dilation,dysfunction.In this era,the aim of treatment of TOF is attempted to preserve pulmonary valve annulus for prevent right ventricular dysfunction in the future.The systemic to pulmonary artery shunt is a palliative procedure or known as staged repair for symptomatic patients with TOF.The modified Blalock-Taussig shunt(mBTS)is the most useful systemic to pulmonary shunt and perform as an initial procedure before complete repair.The mBTS can provide increase pulmonary blood flow as well as improve oxygenation and also promote pulmonary artery(PA)growth.However,the effect of this procedure to promote growth of a pulmonary valve annulus is still debate.Objectives:To compare a growth of pulmonary valve annulus between after staged repair and primary repair in patients with TOF(without pulmonary atresia).Methods:A retrospective case-control study,review of patients with TOF underwent total repair at our hospitals from January 2005 and December 2017 was performed,a total number of 112 patients underwent TOF repair.Twenty-nine patients(26%)underwent a staged repair(mBTS group)and 83(74%)underwent total repair only or primary repair(PR group).We evaluated diameter of pulmonary valve annulus by using echocardiography at the time of first diagnosis and before complete repair on both groups.Results:The age of diagnosis of mBTS group were younger than PR group(p=0.011).Therefore,pulmonary valve annuls were smaller in mBTS group.(Z-score,−2.93±1.42 vs.−1.89±0.97;p=0.001).However,the growth potential of pulmonary valve annulus was increase more than PR group significantly(Z-score,−1.46±1.02 vs.−2.11±1.19;p=0.009)Even though a patent ductus arteriosus was found commonly in PR group(p=0.018).Conclusions:Our results suggest the systemic to pulmonary shunt or mBTS can promote growth of pulmonary valve annulus in patients with TOF.展开更多
Considering the special resistance characteristics of fluids flowing through ducts with small gaps, experiments are performed to investigate the resistance characteristics of single-phase water, which is forced to flo...Considering the special resistance characteristics of fluids flowing through ducts with small gaps, experiments are performed to investigate the resistance characteristics of single-phase water, which is forced to flow through ver tical annuli. The gap sizes are 0.9, 1.4 and 2.4mm, respectively. The experiments are conducted under condition of 1atm. The water in the annuli is heated by high temperature water reversely flowing through the inner tube and the outer annulus. The results show that the flow pattern begin to change from laminar to turbulent before Reynolds number approaches 2000, the flow resistance in annulus has little relations with the temperature difference and ways of being heated, but mainly depends on the ratio of mass flux to the width of annulus.展开更多
基金supported by the Ministry of Education of the Russian Federation(Project KPZU-2023-0002).
文摘A genuine technological issue–the thermal convection of liquid in a rotating cavity–is investigated experimentally.The experiments are conducted within a horizontal annulus with isothermal boundaries. The inner boundaryof the annulus has a higher temperature, thus exerting a stabilising influence on the system. It is shown that whenthe layer rotation velocity diminishes, two-dimensional azimuthally periodic convective rolls, rotating togetherwith the cavity, emerge in a threshold manner. The development of convection is accompanied by a significantintensification of heat transfer through the layer. It is shown that the averaged thermal convection excitation inthe form of a system of two-dimensional rolls occurs against the background of oscillations of a non-isothermalfluid in the cavity reference frame caused by the gravity field. The excitation threshold and the structure ofconvective rolls are consistent with the results of the earlier theoretical studies by the authors performed usingthe equations of “vibrational” convection obtained by the averaging method. Furthermore, the experiments haverevealed a new type of averaged flow in the form of a spatially periodic system of toroidal vortices. It is shown thata steady streaming, excited by the inertial oscillations of the fluid, is responsible for the generation of the toroidalvortices. These flows develop in a non-threshold manner and are most clearly manifested in a case of resonantexcitation of one of the inertial modes.
基金Project (2009AA03Z534) supported by the Hi-tech Research and Development Program of China Project (2006CB605203) supported by National Basic Research Program of China
文摘A comprehensive mathematical model of annulus-electromagnetic direct chill (A-EMDC) casting of A357 aluminum alloy was established with corresponding experimental verification. The model was based on a combination of the commercial finite element package ANSYS and the commercial finite volume package FLUENT. The effects of structural parameters on fluid flow, temperature field and solidification during A-EMDC process were investigated numerically. The results show that structural parameters such as annulus gap width, annulus gap position, and centre pipe length influence the flow and temperature fields. The smaller the annulus gap width is, the more uniform the temperature is, and the smaller the temperature gradient is. With increasing the centre pipe length, the circular flow would decrease due to the dislocation of centre pipe. Specially, when the annulus gap is located at periphery of the billet, the temperature gradient of the longitudinal direction in the solidification region falls evidently.
文摘AIM To apply real time three-dimensional transesophageal echocardiography(RT3D TEE) for quantitative and qualitative assessment of the mitral valve annulus(MVA) and tricuspid valve annulus(TVA) in the same patient.METHODS Our retrospective cohort study examined the MVA and TVA in 49 patients by RT3 D TEE. MVA and TVA shape were examined by TEE. The MVA and TVA volume data set images were acquired in the mid esophageal 4-chamber view. The MVA and TVA were acquired separately, with optimization of each for the highest frame rate and image quality. The 3D shape of the annuli was reconstructed using the Philips~? Q lab, MVQ ver. 6.0 MVA model software. The end-systolic frame was used. The parameters measured and compared were annular area, circumference, high-low distances(height), anterolateralposterolateral(ALPM), and anteroposterior(AP) axes. RESULTS A total of 49 patients(mean age 61 ± 14 years, 45% males) were studied. The ALPM and the AP axes of the MVA and TVA are not significantly different. The ALPM axis of the MVA was 37.9 ± 6.4 mm and 38.0 ± 5.6 mm for the TVA(P = 0.70). The AP axis of the MVA was 34.8 ± 5.7 mm and 34.9 ± 6.2 mm for the TVA(P = 0.90). The MVA and the TVA had similar circumference and area. The circumference of the MVA was 127.9 ± 16.8 mm and 125.92 ± 16.12 mm for the TVA(P = 0.23). The area of the MVA was 1103.7 ± 307.8 mm^2 and 1131.7 ± 302.0 mm^2 for the TVA(P = 0.41). The MVA and TVA are similar oval structures, but with significantly different heights. The ALPM/AP ratio for the MVA was 1.08 ± 0.33 and 1.09 ± 0.28 for the TVA(P < 0.001). The height for the MVA and TVA was 9.23 ± 2.11 mm and 4.37 ± 1.48 mm, respectively(P < 0.0001). CONCLUSION RT3 D TEE plays an unprecedented role in the management of valvular heart disease. The specific and exclusive shape of the MVA and TVA was revealed in our study of patients studied. Moreover, the intricate codependence of the MVA and the TVA depends on their distinctive shapes. This realization seen from our study will allow us to better understand the role valvular disease plays in disease states such as hypertrophic cardiomyopathy and pulmonary hypertension.
基金supported by the National Natural Science Foundation of China (81171479, 51303120, 81471790)the China Postdoctoral Science Foundation (2012M521121)+2 种基金the Natural Science Foundation of Jiangsu Province (BK20130335)the Jiangsu Provincial Special Program of Medical Science (BL2012004)the Priority Academic Program Development of Jiangsu Higher Education Institutions
文摘Annulus fibrosus (AF) tissue engineering has recently received increasing attention as a treatment for intervertebral disc 0VD) degeneration; however, such engineering remains challenging because of the remarkable complexity of AF tissue. In order to engineer a functional AF replacement, the fabrication of cell-scaffold constructs that mimic the cellular, biochemical and structural features of native AF tissue is critical. In this study, we fabricated aligned fibroua polyurethane scaffolds using an electrospinning technique and used them for culturing AF-derived-stem/progenitor cells (AFSCs). Random fibrous scaffolds, also prepared via electrospinningy were used as a control. We compared the morphology, proliferation, gene expression and matrix production of AFSCs on aligned scaffolds and random scaffolds. There was no apparent difference in the attachment or proliferation of cells cultured on aligned scaffolds and random scaffolds. However, compared to cells on random scaffolds, the AFSCs on aligned scaffolds were more elongated and better aligned, and they exhibited higher gene expression and matrix production of coUagen-I and aggrecan. The gene expression and protein production of coUagen-II did not appear to differ between the two groups. Together, these findings indicate that aligned fibrous scaffolds may provide a favourable microenvironment for the differentiation of AFSCs into cells similar to outer AF cells, which predominantly produce collagen-I matrix.
文摘Miniaturization of electronic equipment has forced researchers to devise more effective methods for dissipating the generated heat in these devices.In this study,two methods,including porous media inserting and adding nanoparticles to the base fluid,are used to improve heat transfer in an annulus heated on both walls.To study porous media insert,porous ribs are used on the outer and inner walls independently.The results show that when porous ribs are placed on the outer wall,although the heat transfer enhances,the pressure drop increment is so considerable that performance number (the ratio of heat transfer enhancement pressure increment,PN) is less than unity for all porous rib heights and porous media permeabilities that are studied.On the other hand,the PN of cases where porous ribs were placed on the inner wall depends on the Darcy number (Da).For example,for ribs with Da=0.1 and Da=0.0001,the maximum performance number,PN=4,occurs at the porous ribs height to hydraulic diameter ratios H/Dh=1 and H/Dh=0.25.Under these conditions,heat transfer is enhanced by two orders of magnitude.It is found that adding 5% nanoparticles to the base fluid in the two aforementioned cases improves the Nusselt number and PN by 10%–40%.
基金Project(2012AA040105)supported by the High-tech Research and Development Program of ChinaProject(2014CB643300)supported by National Basic Research Program of ChinaProject(51741034)supported by National Natural Science Foundation of China
文摘Stress corrosion cracking (SCC) behavior of P 110 tubing steel in simulated C02 injection well annulus environments was investigated through three-point bent tests, potentiodynamic polarization and EIS measurements. The results demonstrate that SCC of P110 tubing steel could occur in acidulous simulated environment, and the sensitivity of SCC increases with the decrease ofpH, as well as increase of sulfide concentration and total environmental pressure. Both anodic dissolution and hydrogen embrittlement make contributions to the SCC. Adequate concentration of corrosion inhibitor can inhibit the occurrence of SCC on account of the inhibition of localized anodic dissolution and cathodic hydrogen evolution.
文摘The present work relates to a numerical investigation of double diffusive mixed convection around a horizontal annulus with a finned inner cylinder.The solutal and thermal buoyancy forces are sustained by maintaining the inner and outer cylinders at uniform temperatures and concentrations.Buoyancy effects are also considered,with the Boussinesq approximation.The forced convection effect is induced by the outer cylinder rotating with an angular velocity(ω)in an anti-clockwise direction.The studies are made for various combinations of dimensionless numbers;buoyancy ratio number(N),Lewis number(Le),Richardson number(Ri)and Grashof number(Gr).The isotherms,isoconcentrations and streamlines as well as both average and local Nusselt and Sherwood numbers were studied.A finite volume scheme is adopted to solve the transport equations for continuity,momentum,energy and mass transfer.The results indicate that the use of fins on the inner cylinder with outer cylinder rotation,significantly improves the heat and mass transfer in the annulus.
基金supported by a grant from National Natural Sciences Foundation of China (No.30700841)
文摘In order to investigate the apoptotic pathway of rabbit annulus fibrosus(AF) cells induced by mechanical overload,an experimental air-pressure model was established in this study to pressurize the rabbit AF cells in vitro.Cells were randomly divided into five groups in which the cells were exposed to a continuous pressure of 1.1 MPa for different lengths of time(0,5,12,24 and 36 h).The cell proliferation and apoptosis were detected by cell counting kit-8(CCK-8) assay and flow cytometry;the alterations in mitochondrial membrane potential were measured by fluorescence microscopy and fluorescence spectrophotometer;the activities of caspase-8 and 9 were determined by spectrophotometry.The results showed that after the cells were subjected to the pressure for 24 or 36 h,the cell proliferation was inhibited;the ratio of cell apoptosis was increased;the mitochondrial membrane potential was decreased;the activity of caspase-9 was enhanced;no activity changes were observed in caspase-8.The results suggested that treatment with a pressure of 1.1 MPa for more than 24 h can lead to the proliferation inhibition and the apoptosis of rabbit AF cells in vitro,and the mitochondrial-dependent pathway is implicated in the pressure-induced AF cell apoptosis.
文摘Heat transfer and entropy generation of developing laminar forced convection flow of water-Al_2O_3 nanofluid in a concentric annulus with constant heat flux on the walls is investigated numerically. In order to determine entropy generation of fully developed flow, two approaches are employed and it is shown that only one of these methods can provide appropriate results for flow inside annuli. The effects of concentration of nanoparticles, Reynolds number and thermal boundaries on heat transfer enhancement and entropy generation of developing laminar flow inside annuli with different radius ratios and same cross sectional areas are studied. The results show that radius ratio is a very important decision parameter of an annular heat exchanger such that in each Re, there is an optimum radius ratio to maximize Nu and minimize entropy generation. Moreover, the effect of nanoparticles concentration on heat transfer enhancement and minimizing entropy generation is stronger at higher Reynolds.
文摘The convective heat transfer of hybrid nanoliquids within a concentric annulus has wide engineering applications such as chemical industries, solar collectors, gas turbines, heat exchangers, nuclear reactors, and electronic component cooling due to their high heat transport rate. Hence, in this study, the characteristics of the heat transport mechanism in an annulus filled with the Ag-MgO/H_2O hybrid nanoliquid under the influence of quadratic thermal radiation and quadratic convection are analyzed. The nonuniform heat source/sink and induced magnetic field mechanisms are used to govern the basic equations concerning the transport of the composite nanoliquid. The dependency of the Nusselt number on the effective parameters(thermal radiation, nonlinear convection,and temperature-dependent heat source/sink parameter) is examined through sensitivity analyses based on the response surface methodology(RSM) and the face-centered central composite design(CCD). The heat transport of the composite nanoliquid for the spacerelated heat source/sink is observed to be higher than that for the temperature-related heat source/sink. The mechanisms of quadratic convection and quadratic thermal radiation are favorable for the momentum of the nanoliquid. The heat transport rate is more sensitive towards quadratic thermal radiation.
基金Supported by the National Natural Science Foundation of China (10726004)the Natural Science Foundation for the Youth of Shandong Province (Q2007A02)
文摘The existence of radial solutions of Δu + λg(|x|)f(u) = 0 in annuli with Dirichlet(Dirichlet/Neumann) boundary conditions is investigated.It is proved that the problems have at least two positive radial solutions on any annulus if f is superlinear at 0 and sublinear at ∞.
基金This study was supported by the National Natural Science Foundation of China (No.81260287).
文摘Improving the closure effect of surgical suture for repair of annulus fibrosus defects remains an unsolved problem.A new type of porcine fibrin glue was reported for the repair of annulus fibrous defects in sheep models in this study.Continuous axial loading test showed that this glue could effectively improve the closure effect of surgical suture for annulus fibrous defect.Magnetic resonance imaging (MRI) of the lumbar spine confirmed that,compared with nonfibrin glue treated intervertebral discs,it contributed to preservation of the nucleus pulposus and maintained the physiological hydration of the intervertebral discs.Moreover,histomorphology evaluation showed that the porcine fibrin glue could partially reverse degeneration of the injured intervertebral discs.Taken together,porcine fibrin glue can effectively enhance the closure effect of surgical suture on annulus fibrosus,improve the repair effect and slow down the degeneration of the intervertebral disc,and provide a potential therapeutic strategy for degenerative intervertebral disc disease.
文摘In this study, integral operational methods are used to investigate the thermally induced transverse vibration of a thin elliptic annulus plate with elastic supports at both radial boundaries.The axisymmetric temperature distribution is determined by the heat conduction differential equation and its corresponding boundary conditions by employing a unified integral transform technique by use of Mathieu functions and modified Mathieu functions. The solution of thermally induced vibration of the plate with both ends encased with elastic supports is obtained by employing an integral transform for double Laplace differential equation. The thermal moment is derived on the basis of temperature distribution, and its stresses are obtained based on resultant bending moments per unit width. The numerical calculations of the distributions of the transient temperature and its associated stress distributions are shown in the figures.
基金supported by the Major Program of the National Natural Science Foundation of China(Grant No.51239005)the National Natural Science Foundation of China(Grant No.11404147)+3 种基金the Natural Science Foundation of Jiangsu Province,China(Grant No.BK20140519)the China Postdoctoral Science Foundation(Grant No.2015M571672)the Research Fund for Advanced Talents of Jiangsu University,China(Grant No.11JDG118)the Training Project of Young Backbone Teachers of Jiangsu University,China
文摘We report an acoustic focusing lens composed of two-layer annuluses made of metal cylinders in air. We find that the cylindrical waves can be focused into a perfect point without diffraction in the centre of the annuluses, which arises from the Mie-resonance modes in the annuluses. The focusing frequencies are related to the size of the inner annulus, and the focusing effect can be applied to the annuluses with different shapes and incident positions. Interesting applications of the focusing lens in the acoustic beam splitter and directional transmitter with energy enhancement are further discussed.
文摘Thermophoresis is an important mechanism of micro-particle transport due to temperature gradients in the surrounding medium.It has numerous applications,especially in the field of aerosol technology.This study has numerically investigated the thermophoretic deposition efficiency of particles in a laminar gas flow in a concentric annulus using the critical trajectory method.The governing equations are the momentum and energy equations for the gas and the particle equations of motion.The effects of the annulus size,particle diameter,the ratio of inner to outer radius of tube and wall temperature on the deposition efficiency were studied for both developing and fully-developed flows.Simulation results suggest that thermophoretic deposition increases by increasing thermal gradient,deposition distance,and the ratio of inner to outer radius,but decreases with increasing particle size.It has been found that by taking into account the effect of developing flow at the entrance region,higher deposition efficiency was obtained,than fully developed flow.
文摘In this paper, boiling heat transfer in a vertical annulus with inner side heated with and without air introduction is experimentally studied. Results show that boiling heat transfer is significantly enhanced by the introduction of air. When air is introduced into the liquid with a temperature below boiling point, the enhancement of heat transfer is also detected. It is concluded from the study that the heat transfer enhanced by introduction of inert gas is due to the liquid vaporization at the gas-liquid interface near the wall, which removes a large amount of latent heat and lowers the interfacial temperature considerably. Thus the gas-liquid interface acts as a 'heat sink'and the heat transfer is augmented significantly.
基金the Strategic Cooperation Technology Projects of CNPC and CUPB(ZLZX2020-03)China Scholarship Council(201906440166)for their financial supportfinancial support provided by the Natural Sciences and Engineering Research Council of Canada(NSERC RGPIN-2016-04647 KURU)。
文摘Hole cleaning is a complex process as there are many variables affecting cuttings removal(e.g.drilling fluid type,density,flow rate and rheological properties,cuttings size,drill pipe rotation speed).With the increasing number of drilling small diameter wells(e.g.coiled tubing drilling applications,ultra-deep wells drilled for exploitations of unconventional oil and gas resources),the wall resistance of the micro annulus also emerges as one of the most critical factors affecting the cuttings accumulation in wellbore.The eccentricity of drill pipes commonly observed during the drilling process of ultra-deep well and coiled tubing well makes the wall resistance effect on the cuttings transport even more prominent.Understanding the wall resistance effect on the particle settling behavior in eccentric annuli is,therefore,crucial for hydraulic design of efficient cuttings transport operations in these wells.In this study,a total of 196 sets of particle settling experiments were carried out to investigate the particle settling behavior in eccentric annuli filled with power-law fluids.The test matrix included the eccentricity ranges of 0-0.80,the dimensionless diameter ranges of 0.13-0.75 and the particle Reynolds number ranges of 0.09-32.34.A high-speed camera was used to record the particle settling process and determine the influences of the eccentricity,the dimensionless diameter,the fluid rheological properties,and the solid particle characteristics on the wall factor and the particle settling velocity.The functional relationship among the dimensionless diameter,the particle Reynolds number,and the wall factor was determined by using the method of controlling variables.An eccentric annulus wall factor model with average relative error of 5.16%was established.Moreover,by introducing Archimedes number,an explicit model of particle settling velocity in the eccentric annulus with average relative error of 10.17%was established.A sample calculation of particle settling velocity was provided to show the application of the explicit model.Results of this study can be used as a guideline by field engineers to improve hydraulic design of cuttings transport operations in concentric and eccentric annuli.
基金supported by the National Natural Science Foundation of China (No. 10672189)
文摘A thermoelastic problem of a circular annulus made of functionally graded materials with an arbitrary gradient is investigated. Different from previous works, our analysis neither requires a special form of the gradient of material properties nor demands partitioning the entire structure into a multilayered homogeneous structure. Instead, we propose a new method for solving the thermoelastic problem of a functionally graded circular annulus by transforming it to a Fredholm integral equation. The distribution of thermal stresses and radial displacement can be obtained by solving the resulting equation. Illustrative examples are given to show the effects of varying gradients on the thermal stresses and radial displacement for given temperature changes at the inner and outer surfaces. The results indicate that the thermal stresses can be relaxed for specified gradients, which is beneficial to design an inhomogeneous annulus to maintain structural integrity.
基金This research project is supported by Naresuan University fund.
文摘Background:The surgical outcomes of tetralogy of Fallot(TOF)have evolved dramatically and have resulted in lower mortality rate.Currently,the many cardiac centers have a trend to early single-stage complete repair more than a staged repair.However,the patients who have an early primary repair were required transannular patch augmentation of a pulmonary valve frequently.This effect has been developed a chronic pulmonary insufficiency may lead to right ventricular dilation,dysfunction.In this era,the aim of treatment of TOF is attempted to preserve pulmonary valve annulus for prevent right ventricular dysfunction in the future.The systemic to pulmonary artery shunt is a palliative procedure or known as staged repair for symptomatic patients with TOF.The modified Blalock-Taussig shunt(mBTS)is the most useful systemic to pulmonary shunt and perform as an initial procedure before complete repair.The mBTS can provide increase pulmonary blood flow as well as improve oxygenation and also promote pulmonary artery(PA)growth.However,the effect of this procedure to promote growth of a pulmonary valve annulus is still debate.Objectives:To compare a growth of pulmonary valve annulus between after staged repair and primary repair in patients with TOF(without pulmonary atresia).Methods:A retrospective case-control study,review of patients with TOF underwent total repair at our hospitals from January 2005 and December 2017 was performed,a total number of 112 patients underwent TOF repair.Twenty-nine patients(26%)underwent a staged repair(mBTS group)and 83(74%)underwent total repair only or primary repair(PR group).We evaluated diameter of pulmonary valve annulus by using echocardiography at the time of first diagnosis and before complete repair on both groups.Results:The age of diagnosis of mBTS group were younger than PR group(p=0.011).Therefore,pulmonary valve annuls were smaller in mBTS group.(Z-score,−2.93±1.42 vs.−1.89±0.97;p=0.001).However,the growth potential of pulmonary valve annulus was increase more than PR group significantly(Z-score,−1.46±1.02 vs.−2.11±1.19;p=0.009)Even though a patent ductus arteriosus was found commonly in PR group(p=0.018).Conclusions:Our results suggest the systemic to pulmonary shunt or mBTS can promote growth of pulmonary valve annulus in patients with TOF.
文摘Considering the special resistance characteristics of fluids flowing through ducts with small gaps, experiments are performed to investigate the resistance characteristics of single-phase water, which is forced to flow through ver tical annuli. The gap sizes are 0.9, 1.4 and 2.4mm, respectively. The experiments are conducted under condition of 1atm. The water in the annuli is heated by high temperature water reversely flowing through the inner tube and the outer annulus. The results show that the flow pattern begin to change from laminar to turbulent before Reynolds number approaches 2000, the flow resistance in annulus has little relations with the temperature difference and ways of being heated, but mainly depends on the ratio of mass flux to the width of annulus.