Tunable Multichannel Quantum Routing of Single Photons Based on Single-Mode Microresonators

We have suggested a novel multiport quantum router of single photons with reflection feedback, which is formed by three waveguides coupled with four single-mode microresonators. The single-photon routing probabilities of four channels in the coupled system are studied theoretically by applying the real-space approach. Numerical results indicate that unidirectional routing in these output channels can be effectively implemented, and the router is tunable to route desired frequencies into the output ports, by varying the inter-resonator detunings via spinning resonator technology. Therefore, the proposed multichannel system can provide potential applications in optical quantum communication.

Potassium and calcium channels in different nerve cells act as therapeutic targets in neurological disorders

The central nervous system, information integration center of the body, is mainly composed of neurons and glial cells. The neuron is one of the most basic and important structural and functional units of the central nervous system, with sensory stimulation and excitation conduction functions. Astrocytes and microglia belong to the glial cell family, which is the main source of cytokines and represents the main defense system of the central nervous system. Nerve cells undergo neurotransmission or gliotransmission, which regulates neuronal activity via the ion channels, receptors, or transporters expressed on nerve cell membranes. Ion channels, composed of large transmembrane proteins, play crucial roles in maintaining nerve cell homeostasis. These channels are also important for control of the membrane potential and in the secretion of neurotransmitters. A variety of cellular functions and life activities, including functional regulation of the central nervous system, the generation and conduction of nerve excitation, the occurrence of receptor potential, heart pulsation, smooth muscle peristalsis, skeletal muscle contraction, and hormone secretion, are closely related to ion channels associated with passive transmembrane transport. Two types of ion channels in the central nervous system, potassium channels and calcium channels, are closely related to various neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. Accordingly, various drugs that can affect these ion channels have been explored deeply to provide new directions for the treatment of these neurological disorders. In this review, we focus on the functions of potassium and calcium ion channels in different nerve cells and their involvement in neurological disorders such as Parkinson's disease, Alzheimer's disease, depression, epilepsy, autism, and rare disorders. We also describe several clinical drugs that target potassium or calcium channels in nerve cells and could be used to treat these disorders. We concluded that there are few clinical drugs that can improve the pathology these diseases by acting on potassium or calcium ions. Although a few novel ion-channelspecific modulators have been discovered, meaningful therapies have largely not yet been realized. The lack of target-specific drugs, their requirement to cross the blood–brain barrier, and their exact underlying mechanisms all need further attention. This review aims to explain the urgent problems that need research progress and provide comprehensive information aiming to arouse the research community's interest in the development of ion channel-targeting drugs and the identification of new therapeutic targets for that can increase the cure rate of nervous system diseases and reduce the occurrence of adverse reactions in other systems.

Accurate Interconnection Length and Routing Channel Width Estimates for FPGAs

We study the problem of the prediction of interconnection dimensions for FPGAs, including estimating interconnection length and channel width. Experimental results show that our estimates are more accurate than those of existing methods.

Joint channel assignment and cross-layer routing protocol for multi-radio multi-channel Ad Hoc networks

To study multi-radio multi-channel （MR-MC） Ad Hoc networks based on 802.11, an efficient cross-layer routing protocol with the function of joint channel assignment, called joint channel assignment and cross-layer routing （JCACR）, is presented. Firstly, this paper introduces a new concept called channel utilization percentage （CUP）, which is for measuring the contention level of different channels in a node’s neighborhood, and deduces its optimal value for determining whether a channel is overloaded or not. Then, a metric parameter named channel selection metric （CSM） is designed, which actually reffects not only the channel status but also corresponding node’s capacity to seize it. JCACR evaluates channel assignment by CSM, performs a local optimization by assigning each node a channel with the smaller CSM value, and changes the working channel dynamically when the channel is overloaded. Therefore, the network load balancing can be achieved. In addition, simulation shows that, when compared with the protocol of weighted cumulative expected transfer time （WCETT）, the new protocol can improve the network throughput and reduce the end-to-end average delay with fewer overheads.

Distributed Low-Complexity Channel Assignment for Opportunistic Routing

Opportunistic Routing (OR) involves multiple forwarding candidates to relay packets by taking advantage of the broadcast nature and multi-user diversity of a wireless medium. Compared with Traditional Routing (TR), OR is more suitable in the case of an unreliable wireless link and can evidently improve the end-to-end throughput of Wireless Mesh Networks (WMNs). In this paper, we focus on OR in Multi-Radio Multi-Channel WMNs (MRMC-WMNs). This problem has not been well examined and is considerably more challenging than the OR in single-radio wireless networks considered in the existing literature. First, we validate the advantage of OR in MRMC-WMNs. Second, we propose Low-complexity Channel Assignment for Opportunistic Routing (LcCAOR), which assigns channels to flows according to the interference state of every node. Third, we implement the LcCOAR in a fully distributed manner. The simulation result shows that compared with OR in Single-Radio Single-Channel WMNs (SRSC-WMNs), the proposed OR can significantly enhance the throughput to 87.11% and 100.3% in grid and tree WMNs, respectively.

A TRUST MECHANISM-BASED CHANNEL ASSIGNMENT AND ROUTING SCHEME IN COGNITIVE WIRELESS MESH NETWORKS WITH INTRUSION DETECTION

Cognitive Wireless Mesh Networks(CWMN) is a novel wireless network which combines the advantage of Cognitive Radio(CR) and wireless mesh networks.CWMN can realize seamless in-tegration of heterogeneous wireless networks and achieve better radio resource utilization.However,it is particularly vulnerable due to its features of open medium,dynamic spectrum,dynamic topology,and multi-top routing,etc..Being a dynamic positive security strategy,intrusion detection can provide powerful safeguard to CWMN.In this paper,we introduce trust mechanism into CWMN with intrusion detection and present a trust establishment model based on intrusion detection.Node trust degree and the trust degree of data transmission channels between nodes are defined and an algorithm of calcu-lating trust degree is given based on distributed detection of attack to networks.A channel assignment and routing scheme is proposed,in which selects the trusted nodes and allocates data channel with high trust degree for the transmission between neighbor nodes to establish a trusted route.Simulation re-sults indicate that the scheme can vary channel allocation and routing dynamically according to network security state so as to avoid suspect nodes and unsafe channels,and improve the packet safe delivery fraction effectively.

Improved AODV Routing Protocol Based on Link Stability and Channel Switching

Ad hoc on-demand distance vector( AODV) routing is one of the typical reactive routing protocols of vehicular ad hoc networks( VANET). Considering link stability and channel switching can greatly improve the QoS of protocols,in this paper,we propose a novel routing protocol: optimized cross-layer AODV( CL_ AODV) designed for VANET. It utilizes the frame transmission efficiency( FTE),path bandwidth in media access control( MAC) layer and signal-to-noise ratio( SNIR) in physical( PHY) layer to improve the link stability. In other words,it can increase packet delivery ratio effectively. In addition,end-to-end delay will be decreased based on the channel switching. According to the simulation,it is shown that the packet delivery ratio of CL_AODV is almost up to 99% and the highest compared to AODV and muti-constrained QoS AODV( MQ_ AODV). The delay of CL_AODV is almost half of MQ_ AODV's and 1 /3 of AODV's.Meanwhile,CL_AODV has the highest routing overhead or energy consuming. Because of the feature of VANET,the disadvantage can be ignored.

AN ALGORITHM FOR VLSI CHANNEL ROUTING USING NEURAL NETWORK

The algorithm for VLSI channel routing using Hopfield neural model is discussed inthis paper.The basic methods of mapping VLSI channel routing problem to Hopfield neural net-work,constructing energy function,setting initial neural status,and selecting various parametersare proposed.Finally,some experimental results are given.

A NEW AD HOC ROUTING ALGORITHM BASED ON MINIMIZING THE CHANNEL HANDOFF

How to improve the performance of the wireless Ad Hoc network by utilizing the spectrum resources efficiently has become a hot research topic in recent years. In this paper we propose a reactive routing algorithm that supports multiple channels to improve the performance of the Ad Hoc network based on the minimizing of the channel handoff. Our approach allocates the communication channel during the route discovery, and notifies the allocated channel information to the corresponding node in the route reply packets. Each node in the route tries its best to choose the same channel with the upstream node without interference. The simulation results show that our algorithm performs better than the K-hop distinct protocols in both average delays and network throughputs

A ROUTING PROTOCOL BASED ON INTERFERENCE-AWARE AND CHANNEL-LOAD IN MULTI-RADIO MULTI-CHANNEL AD HOC NETWORKS

Improving capacity and reducing delay are the most challenging topics in wireless ad hoc networks. Nodes that equip multiple radios working on different channels simultaneously permit ef-fective utility of frequency spectrum and can also reduce interference. In this paper, after analyzing several current protocols in Multi-Radio Multi-Channel (MR-MC) ad hoc networks, a new multi-channel routing metric called Integrative Route Metric (IRM) is designed. It takes channel load, inter-flow, and intra-flow interference into consideration. In addition, an MR-MC routing protocol based on Interference-Aware and Channel-Load (MR-IACL) is also presented. The MR-IACL can assign channels and routings for nodes according to channel load and interference degree of links, and optimize channel distribution dynamically to satisfy the features of topology changing and traffic frequent fluctuation during network running. The simulation results show that the new protocol outperforms others in terms of network throughput, end-to-end delay, routing overhead, and network lifetime.

FLOOD ROUTING MODELS IN CONFLUENT AND DIVIDING CHANNELS

By introducing a water depth connecting formula, the hydraulic equations in the dividing channel system were coupled and the relation of discharge distribution between the branches of the dividing channels can be yielded. In this manner, a numerical model for the confluent channels was established to study the variation of backwater effects with the parameters in the channel junction. The meeting of flood peaks in the mainstream and tributary can be analyzed with this model.The flood peak meeting is found to be a major factor for the extremely high water level in the mainstream during the 1998 Yangtze River flood. Subsequently the variations of discharge distribution and water level with channel parameters between each branch in this system were studied as well. As a result, flood evolution caused by Jingjiang River shortcut and sediment deposition in the entrance of dividing channels of the Yangtze River may be qualitatively elucidated.It is suggested to be an effective measure for flood mitigation to enhance regulation capability of reservoirs available upstream of the tributaries and harness branch entrance channels.

Dynamic channel estimation-aware routing protocol in mobile cognitive radio networks for smart IIoT applications

Cognitive Radio Networks(CRNs)have become a successful platform in recent years for a diverse range of future systems,in particularly,industrial internet of things(IIoT)applications.In order to provide an efficient connection among IIoT devices,CRNs enhance spectrum utilization by using licensed spectrum.However,the routing protocol in these networks is considered one of the main problems due to node mobility and time-variant channel selection.Specifically,the channel selection for routing protocol is indispensable in CRNs to provide an adequate adaptation to the Primary User(PU)activity and create a robust routing path.This study aims to construct a robust routing path by minimizing PU interference and routing delay to maximize throughput within the IIoT domain.Thus,a generic routing framework from a cross-layer perspective is investigated that intends to share the information resources by exploiting a recently proposed method,namely,Channel Availability Probability.Moreover,a novel cross-layer-oriented routing protocol is proposed by using a time-variant channel estimation technique.This protocol combines lower layer(Physical layer and Data Link layer)sensing that is derived from the channel estimation model.Also,it periodically updates and stores the routing table for optimal route decision-making.Moreover,in order to achieve higher throughput and lower delay,a new routing metric is presented.To evaluate the performance of the proposed protocol,network simulations have been conducted and also compared to the widely used routing protocols,as a benchmark.The simulation results of different routing scenarios demonstrate that our proposed solution outperforms the existing protocols in terms of the standard network performance metrics involving packet delivery ratio(with an improved margin of around 5–20%approximately)under varying numbers of PUs and cognitive users in Mobile Cognitive Radio Networks(MCRNs).Moreover,the cross-layer routing protocol successfully achieves high routing performance in finding a robust route,selecting the high channel stability,and reducing the probability of PU interference for continued communication.

Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx

To date,several molecules have been found to facilitate iron influx,while the types of iron influx channels remain to be elucidated.Here,Piezo1 channel was identified as a key iron transporter in response to mechanical stress.Piezo1-mediated iron overload disturbed iron metabolism and exaggerated ferroptosis in nucleus pulposus cells(NPCs).Importantly,Piezo1-induced iron influx was independent of the transferrin receptor(TFRC),a well-recognized iron gatekeeper.Furthermore,pharmacological inactivation of Piezo1 profoundly reduced iron accumulation,alleviated mitochondrial ROS,and suppressed ferroptotic alterations in stimulation of mechanical stress.Moreover,conditional knockout of Piezo1(Col2a1-CreERT Piezo1^(flox/flox))attenuated the mechanical injury-induced intervertebral disc degeneration(IVDD).Notably,the protective effect of Piezo1 deficiency in IVDD was dampened in Piezo1/Gpx4 conditional double knockout(cDKO)mice(Col2a1-CreERT Piezo1^(flox/flox)/Gpx4^(flox/flox)).These findings suggest that Piezo1 is a potential determinant of iron influx,indicating that the Piezo1-iron-ferroptosis axis might shed light on the treatment of mechanical stress-induced diseases.

Virtual Channel Routing Based Neural Networks in B-ISDN

his paper discusses virtual path(VP) and virtual channel (VC) routing problems in broadband networks, proposes a Hopfield neural VC routing algorithm in homogeneous VPbased ATM networks, and sets up neural networks energy function and neuron state equation. The objective is to minimize call blocking rate for future requests. From the simulation results, it can be concluded that under any traffic pattern and in realtime VC routing, the proposed algorithm is both efficient and effective.

Crosstalk and Wire Length Reduction in the Non-Manhattan Channel Routing

A novel framework for non-Manhattan channel routing considering crosstalk and wire length reduction is proposed. To handle crosstalk and wire length reduction problem, an improved non-Manhattan router in the gridded routing model is developed, and a novel rerouting algorithm based on segment-rerouting technique and layer reassignment is presented. Simulation exDeriments demonstrate that our algorithm achieves verv good results.

Opportunistic Routing with Multi-Channel Cooperative Neighbour Discovery

Due to the scattered nature of the network,data transmission in a dis-tributed Mobile Ad-hoc Network(MANET)consumes more energy resources(ER)than in a centralized network,resulting in a shorter network lifespan(NL).As a result,we build an Enhanced Opportunistic Routing(EORP)protocol architecture in order to address the issues raised before.This proposed routing protocol goal is to manage the routing cost by employing power,load,and delay to manage the routing energy consumption based on theflooding of control pack-ets from the target node.According to the goal of the proposed protocol techni-que,it is possible to manage the routing cost by applying power,load,and delay.The proposed technique also manage the routing energy consumption based on theflooding of control packets from the destination node in order to reduce the routing cost.Control packet exchange between the target and all the nodes,on the other hand,is capable of having an influence on the overall efficiency of the system.The EORP protocol and the Multi-channel Cooperative Neighbour Discovery(MCCND)protocol have been designed to detect the cooperative adja-cent nodes for each node in the routing route as part of the routing path discovery process,which occurs during control packet transmission.While control packet transmission is taking place during the routing path discovery process,the EORP protocol and the Multi-channel Cooperative Neighbour Discovery(MCCND)protocol have been designed to detect the cooperative adjacent nodes for each node in the routing.Also included is a simulation of these protocols in order to evaluate their performance across a wide range of packet speeds using Constant Bit Rate(CBR).When the packet rate of the CBR is 20 packets per second,the results reveal that the EORP-MCCND is 0.6 s quicker than the state-of-the-art protocols,according to thefindings.Assuming that the CBR packet rate is 20 packets per second,the EORP-MCCND achieves 0.6 s of End 2 End Delay,0.05 s of Routing Overhead Delay,120 s of Network Lifetime,and 20 J of Energy Consumption efficiency,which is much better than that of the state-of-the-art protocols.

Lithium-Ion Charged Polymer Channels Flattening Lithium Metal Anode

The concentration difference in the near-surface region of lithium metal is the main cause of lithium dendrite growth.Resolving this issue will be key to achieving high-performance lithium metal batteries(LMBs).Herein,we construct a lithium nitrate(LiNO_(3))-implanted electroactiveβphase polyvinylidene fluoride-co-hexafluoropropylene(PVDF-HFP)crystalline polymorph layer(PHL).The electronegatively charged polymer chains attain lithium ions on the surface to form lithium-ion charged channels.These channels act as reservoirs to sustainably release Li ions to recompense the ionic flux of electrolytes,decreasing the growth of lithium dendrites.The stretched molecular channels can also accelerate the transport of Li ions.The combined effects enable a high Coulombic efficiency of 97.0%for 250 cycles in lithium(Li)||copper(Cu)cell and a stable symmetric plating/stripping behavior over 2000 h at 3 mA cm^(-2)with ultrahigh Li utilization of 50%.Furthermore,the full cell coupled with PHL-Cu@Li anode and Li Fe PO_(4) cathode exhibits long-term cycle stability with high-capacity retention of 95.9%after 900 cycles.Impressively,the full cell paired with LiNi_(0.87)Co_(0.1)Mn_(0.03)O_(2)maintains a discharge capacity of 170.0 mAh g^(-1)with a capacity retention of 84.3%after 100 cycles even under harsh condition of ultralow N/P ratio of 0.83.This facile strategy will widen the potential application of LiNO_(3)in ester-based electrolyte for practical high-voltage LMBs.

Towards Blockchain-Based Secure BGP Routing,Challenges and Future Research Directions

Border Gateway Protocol(BGP)is a standard inter-domain routing protocol for the Internet that conveys network layer reachability information and establishes routes to different destinations.The BGP protocol exhibits security design defects,such as an unconditional trust mechanism and the default acceptance of BGP route announcements from peers by BGP neighboring nodes,easily triggering prefix hijacking,path forgery,route leakage,and other BGP security threats.Meanwhile,the traditional BGP security mechanism,relying on a public key infrastructure,faces issues like a single point of failure and a single point of trust.The decentralization,anti-tampering,and traceability advantages of blockchain offer new solution ideas for constructing secure and trusted inter-domain routing mechanisms.In this paper,we summarize the characteristics of BGP protocol in detail,sort out the BGP security threats and their causes.Additionally,we analyze the shortcomings of the traditional BGP security mechanism and comprehensively evaluate existing blockchain-based solutions to address the above problems and validate the reliability and effectiveness of blockchain-based BGP security methods in mitigating BGP security threats.Finally,we discuss the challenges posed by BGP security problems and outline prospects for future research.

The Channel Branches & Network Vessels on the Tianhui Lacquered Meridian Figurine——Taking the Heart-Regulated Channel as an Example

Along with the surge of unearthed medical literature and cultural relics in recent years,a network of channels in the system of medical conduit vessels(meridians) during the early Western Han dynasty has become much clearer gradually.In it,the increasing number of channel branches,network vessels and needle insertion holes(acupoints) is an important feature of the development of channel medicine during the Western Han dynasty.This is not only a reflection of the expanding requirements of the theoretical system of the main trunk channels and other vessels,but also an inevitable result of the continuous enrichment and accumulation of clinical experience.This article integrates the information about channel branches,network vessels,inscriptions,dots and further relics on the Tianhui(天回) Lacquered Meridian Figurine to compare the unearthed literature of the channel genre with the transmitted classical literature about acupuncture.The “Heart-Regulated Channel” in Medical Manuscripts on Bamboo Slips from Tianhui(《天回医简》) serves as an example to explain the occurrence,development and changes of the channel branches and network vessels in the early system of medical channels.

Deep learning for joint channel estimation and feedback in massive MIMO systems

The great potentials of massive Multiple-Input Multiple-Output(MIMO)in Frequency Division Duplex(FDD)mode can be fully exploited when the downlink Channel State Information(CSI)is available at base stations.However,the accurate CsI is difficult to obtain due to the large amount of feedback overhead caused by massive antennas.In this paper,we propose a deep learning based joint channel estimation and feedback framework,which comprehensively realizes the estimation,compression,and reconstruction of downlink channels in FDD massive MIMO systems.Two networks are constructed to perform estimation and feedback explicitly and implicitly.The explicit network adopts a multi-Signal-to-Noise-Ratios(SNRs)technique to obtain a single trained channel estimation subnet that works well with different SNRs and employs a deep residual network to reconstruct the channels,while the implicit network directly compresses pilots and sends them back to reduce network parameters.Quantization module is also designed to generate data-bearing bitstreams.Simulation results show that the two proposed networks exhibit excellent performance of reconstruction and are robust to different environments and quantization errors.