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A randomized trail comparing primary percutaneous coronary intervention with a strategy of short-acting thrombolysis and immediate planned primary percutaneous coronary intervention in acute myocardial infarction
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作者 傅向华 《介入放射学杂志》 CSCD 2003年第S1期151-,共1页
Objective This study was to evaluate the efficacy and safety of a short acting reduced dose fibrinolytic regimen to promote early infarct related artery (IRA) patency for acyute myocardial infarction (AMI) patients re... Objective This study was to evaluate the efficacy and safety of a short acting reduced dose fibrinolytic regimen to promote early infarct related artery (IRA) patency for acyute myocardial infarction (AMI) patients referred for percutaneous coronary intervention (PCI).Methods Following aspirin and heparin, 166 patients were randomized to a 50 mg bolus of recombinant tissue type plasminogen activator(rt PA) or to a same volume sodium chloride injection followed by immediate primary PCI. The end points included patency rates on catheterization laboratory (cath lab) arrival, revascularization results when PCI was performed, complication rates, left ventricular function and restored patency rate following PCI. Results Patency on cath lab arrival was 64% with rt PA (34% TIMI 3,30% TIMI 2), while 31% of placebo (13% TIMI 3, 18% TIMI 2). There was no difference in the restored TIMI 3 rates of IRA between the two groups (85% vs 87%). No difference were observed in stroke or major bleeding. Left ventricular function was similar in both groups (52±9% vs 50±8%), but left ventricular ejection fraction fraction (LVEF) was higher with patent IRA (TIMI 3) on cath lab arrival than that of others (56±12% vs 48±10%).Conclusions Strategy thrombolytic regimens were compatible with subsequent PCI lead to more frequenc early recanalization (before cath lab arrival), which facilitates greater left ventricular function preservation with no augmentation of adverse events. 展开更多
关键词 in of A randomized trail comparing primary percutaneous coronary intervention with a strategy of short-acting thrombolysis and immediate planned primary percutaneous coronary intervention in acute myocardial infarction with
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An Audio Zero-Watermark Scheme Based on Energy Comparing 被引量:7
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作者 YANG Yu LEI Min +3 位作者 CHENG Mingzhi LIU Bohuai LIN Guoyuan XIAO Da 《China Communications》 SCIE CSCD 2014年第7期110-116,共7页
Zero-watermark technique,embedding watermark without modifying carriers,has been broadly applied for copyright protection of images.However,there is little research on audio zerowatermark.This paper proposes an audio ... Zero-watermark technique,embedding watermark without modifying carriers,has been broadly applied for copyright protection of images.However,there is little research on audio zerowatermark.This paper proposes an audio zero-watermark scheme based on energy relationship between adjacent audio sections.Taking use of discrete wavelet transformation(DWT),it gets power approximations,or energies,of audio segments.Then,it extracts the audio profile,i.e.the zero-watermark,according to the relative size of energies of consecutive fragments.The experimental results demonstrate that the proposed scheme is robust against general malicious attacks including noise addition,resampling,low-pass filtering,etc.,and this approach effectively solves the contradiction between inaudibility and robustness. 展开更多
关键词 zero-watermark audio water-marking scheme energy comparing
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Comparing the rhythm and frequency of heart,breathing and knee movement in Tai Chi Chuan
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作者 魏珊珊 刘宇 李立 《医用生物力学》 EI CAS CSCD 2009年第S1期150-151,共2页
Background:The basic exercise involved in TCC is a series of individual movements that are linked together in a continuous manner and that flow smoothly from one movement to another.Deep breathing and mental concentra... Background:The basic exercise involved in TCC is a series of individual movements that are linked together in a continuous manner and that flow smoothly from one movement to another.Deep breathing and mental concentration are also required to achieve harmony 展开更多
关键词 comparing the rhythm and frequency of heart breathing and knee movement in Tai Chi Chuan
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Preparative Resolution of Gatifloxacin Enantiomers with Pre-Column Esterification Strategy and Comparing Their Enantioselectivity to Bacteria and Antibody 被引量:1
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作者 ZHANG Chi Jian LEI Hong Tao +4 位作者 HUANG Xiao Long LIU Ying Ju CAI Kai XU Zhen Lin SUN Yuan Ming 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2015年第2期157-160,共4页
Gatifloxacin (GFX) is a kind of chiral fluoroquinolones compound due to the methyl group at the C-3 position of the piperazine ring[1]. Although the enantiomers of GFX show similar levels of antimicrobial activity a... Gatifloxacin (GFX) is a kind of chiral fluoroquinolones compound due to the methyl group at the C-3 position of the piperazine ring[1]. Although the enantiomers of GFX show similar levels of antimicrobial activity and pharmacokinetics[2], the other biological activities (i.e., toxicity or enantioselective recognition to various receptors in vivo) of GFX enantiomers have not yet been studied. With this in mind, we developed a rapid and cost-effective high performance liquid chromatographic (HPLC) separation procedure for GFX enantiomers with a pre-column esterification strategy. 展开更多
关键词 Preparative Resolution of Gatifloxacin Enantiomers with Pre-Column Esterification Strategy and comparing Their Enantioselectivity to Bacteria and Antibody DEA than
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Comparing of Aviation Network Structure of Mid-south,Northwest and Southwest of China Based on Hierarchical Index Model 被引量:1
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作者 Cheng Xiangjun Yang Fang Xie Li 《Journal of Traffic and Transportation Engineering》 2020年第1期14-19,共6页
In order to compare the aviation network of mid-south,northwest and southwest of China to reveal the structure similarity and difference for providing quantitative evidence to construct regional aviation network and i... In order to compare the aviation network of mid-south,northwest and southwest of China to reveal the structure similarity and difference for providing quantitative evidence to construct regional aviation network and improve its structure,hierarchical index model of regional aviation network was established through dividing the aviation network into layers to research its structure characters.Data matrixes were defined to record the basic state of regional aviation network.Index matrixes were constructed to describe the quantitative features of regional aviation network.On the basis of these indexes,several structure indexes of all layers of aviation network were calculated to show the structure features of aviation network,such as ratio of passenger volume within the region with across the region,share rate of passenger volume among layers,ratio of average number of airline for each airport,ratio of average passenger volume for each airline and ratio of airline rate.According to the statistical data,similar structure of share rate of passenger volume among layers and average passenger volume for each airline in their regional aviation network was found after calculating.But on the side of ratio of passenger volume within the region with across the region,ratio of average number of airlines for each airport and ratio of airline rate were different. 展开更多
关键词 Regional aviation network comparing of structure hierarchical index model index matrix structure index
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Comparing the Effectiveness of Coatings on Carbide andCermet Cutting Tool Inserts
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作者 K.H. W.Seah M.Rahman and C.H.Lee (Dept. of Mech. & Prod. Eng., National University of Singapore, 10 Kent Ridge Crescent, Singapore 0511 T.N.Goh (Dept. of Ind. & Sys. Eng., National University of Singapore, 10 Kent Ridge Crescent, Singapore 0511) 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 1995年第4期269-275,共7页
A series of metal cutting experiments was performed on a CNC lathe to evaluate the performance of various coatings on different tool substrates. The workpiece material was plain medium carbon steel and the cutting too... A series of metal cutting experiments was performed on a CNC lathe to evaluate the performance of various coatings on different tool substrates. The workpiece material was plain medium carbon steel and the cutting tool materials were carbide and cermet inserts coated with various single as well as multilayer coatings. Machining was done under various cutting conditions of speed and feed-rate, and for various durations of Cutting. The output parameters studied were the cutting forces (axial, radial and tangential), the surface roughness of the workpiece, as well as the tool wear (crater and flank wear). From these results, the performances of the various cutting inserts are evaluated and compared. Results show that cutting forces are significantly lower when using coated cermets than when using coated carbides although different coatings on the same substrate also result in different cutting forces. However, there is less difference in the surface roughness of the finished workpiece for the various coatings and substrates. 展开更多
关键词 TOOL comparing the Effectiveness of Coatings on Carbide andCermet Cutting Tool Inserts
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Comparing a small gravel-less perforated pipe leach fields (GPPLF) to a medium one in treating domestic sewage
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作者 Yiheng Yang Chengduan Wang Zhenhua Dang 《Natural Science》 2012年第3期192-197,共6页
There were obvious differences between a medium gravel-less perforated pipe leach fields and a small system in the treatment of demestic sewage with the change of influent quality. In small system, COD removal rate wa... There were obvious differences between a medium gravel-less perforated pipe leach fields and a small system in the treatment of demestic sewage with the change of influent quality. In small system, COD removal rate was 91%, ammonia nitrogen removal rate was 90%, total nitrogen was 58%. In medium system, COD removal rate was 86.07%, ammonia nitrogen removal rate was 45.3%, and total nitrogen was 48.2%. This paper studied on the differences. Its main reasons were as follows: differences in opening rate (perforated area account of the total area in infiltration pipe), air flow conditions, exterior environment, and wastewater distribution. Considering those problems, Solutions and applications for the development of GPPLF are given. 展开更多
关键词 Gravel-Less Perforated PIPE LEACH FIELDS Pollutants Removal Rate comparing Component Formatting Style STYLING Insert
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Comparing Coordination Abilities of 10-11 Years Old Girls Practicing Basketball and Rhythmic Gymnastic
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作者 Georgi Venelinov Brestnichki 《Journal of Sports Science》 2015年第3期134-137,共4页
The words---coordination, coordination abilities and coordination training are getting more and more popular among the coaches in different sports. The rhythm makes the movement logical, easy and correct done. The pur... The words---coordination, coordination abilities and coordination training are getting more and more popular among the coaches in different sports. The rhythm makes the movement logical, easy and correct done. The purpose of this study is to determine any difference between the coordination abilities of 10-11 years old gifts practicing basketball and rhythmic gymnastics. In that study, we have tested 40 girls at the age of 10-11 years practicing basketball and rhythmic gymnastic. We have tested them by 7 coordination tests. The results from the tests have been calculated in math-statistic methods and we have used descriptive statistic and t-test by Student with guaranteed probability Pt 〉 95 %. Ten-eleven old girls practicing rhythmic gymnastic have advantage against the girls practicing basketball in all 7 tests examining coordination abilities. The girls practicing rhythmic gymnastic, guaranteed by statistic, have better results in the balance and rhythmic abilities than the girls practicing basketball game. That statement is showing us that at this age the rhythmic gymnastic or elements from rhythmic gymnastic should be used for developing balance and rhythmic ability, which are very important for the basketball game. 展开更多
关键词 comparing COORDINATION 10-11 years old GIRLS BASKETBALL rhythmic GYMNASTICS
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Comparing blood security from nonprofit voluntary and profit blood donor
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《中国输血杂志》 CAS CSCD 2001年第S1期327-,共1页
关键词 comparing blood security from nonprofit voluntary and profit blood donor
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Comparing High-resistance Grounding Method with Resonance Grounding Method for Large Generators
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作者 Yao Huannian Cao Meiyue(Xiamen Electric Power Administration) 《Electricity》 1997年第3期22-25,共4页
For large generators, the problem of high-resistance grounding method and the advantages of resonance, grounding method are discussed in detail, and an overall comparison is given in this paper. It is recommended that... For large generators, the problem of high-resistance grounding method and the advantages of resonance, grounding method are discussed in detail, and an overall comparison is given in this paper. It is recommended that the latter should be adopted so as to increase the operation reliability of large generators and power systems. 展开更多
关键词 HIGH comparing High-resistance Grounding Method with Resonance Grounding Method for Large Generators
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A randomized double-blind multicenter study on comparing levonorgestrel and mifepristone for emergency contraception
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作者 吴尚纯 王翠萍 +6 位作者 王幼劬 程渭玉 左诗慧 李红 徐晓 汪蓉芬 董敬 《生殖医学杂志》 CAS 1999年第S1期43-46,共4页
Objective: To compare the efficacy and side effects of levonorgestrel and low dose mifepristone in emergency contraception. Method: The study is a randomized double--blind multicenter comparative trial. A total of 1, ... Objective: To compare the efficacy and side effects of levonorgestrel and low dose mifepristone in emergency contraception. Method: The study is a randomized double--blind multicenter comparative trial. A total of 1, 276 women with unprotected intercourse within 72 hours were allocated to one of the two study groups. In the levonorgestrel (LNG) group, 0. 75 mg LNG was taken twice, 12 hours apart, whereas in the mifepristone (Mife) group, a single dose of 10 mg mifepristone was taken and a placebo 12 hours after. Follow--up visit was paid on the seventh day of the expected next menstruation to evaluate the contraceptive efficacy and side effects. Contraceptive efficacy was calculated by Dixon’s method. Result:In the LNG group 20 pregnancies occurred among 643 women, while in the Mife group 9 pregnancies occurred among 633 women. The pregnancy rates were 3. 10% and 1. 43% respectively. Contraceptive efficacy rate of preventing pregnancy was 59. 16% and 79. 73%, the difference was statistically significant (P<O. 05). The incidence of various side effects, which were mild, was less than 10%. There was no statistical difference between the two groups. The percentage of subjects who had their next menstruation 3 days earlier or later than their expected menstruation in LNG group and Mife group was 77. 7% and 78. 5% respectively. Conclusion: Use of levonorgestrel or low dose mifepristone for emergency contraception is effective and safe. 展开更多
关键词 mergency CONTRACEPTION LEVONORGESTREL MIFEPRISTONE RANDOMIZED comparative TRIAL
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Reflexivity in the Transformation of Higher Education:Comparing Japan,South Korea,and Taiwan
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作者 Po-Fen Tai 《Cultural and Religious Studies》 2018年第11期613-629,共17页
The objective of this paper is to compare the transformation of higher educations in Japan,South Korea,and Taiwan.The higher education systems in these societies were established and transformed from homologous Japane... The objective of this paper is to compare the transformation of higher educations in Japan,South Korea,and Taiwan.The higher education systems in these societies were established and transformed from homologous Japanese Imperial Universities,and developed toward various higher education systems intermediated by policies under international and domestic contexts.Using second hand data,the results show the common characteristics of these cases from state-led national elitism to market-led massification by means of privatization and commercialization.However,some differences exist in their finances resources,enrolment rates,policies for tuition fees and mostly important,job rewards for those who obtain higher education degrees,comparing to high school ones.The rise of reflexivity further suggests that the right of access to higher education has been changed from institutional limited opportunities,to the actors who decide when,why,and how to accept higher education.The facts imply that the states have to adjust and re-define their roles in higher education,and diverse programs and learning methods will be provided for multiple students in the future. 展开更多
关键词 REFLEXIVITY comparative HIGHER education MARKETIZATION COMMERCIALIZATION
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Practical Challenges in Comparing Chinese and American Local Government
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作者 Matthew S. Mingus Cheng Li Wang Yan 《International Relations and Diplomacy》 2015年第10期661-680,共20页
Parts of China are an advanced industrial society with excellent public transportation, universities, industry, and other modern features; while other parts (geographically and functionally) remain a developing nati... Parts of China are an advanced industrial society with excellent public transportation, universities, industry, and other modern features; while other parts (geographically and functionally) remain a developing nation. For China, to build a stronger and more equitable society requires much work to develop governance at the local level. In pursuit of this goal, China actively seeks to learn lessons from abroad, including from American local government. This article examines the similarities and differences between these two nations and their systems of government toward the end of identifying potential challenges to Chinese efforts to learn from American-style local governance. This is grounded in policy transfer theory, which guides the discussion of how to learn from other jurisdictions--from other jurisdictions within the nation, from other points in time within the nation, and from other nations. Perhaps the ultimate questions are, "Should China continue efforts to learn from external models or focus its energy internally?" and "Does China need a more clearly defined governance model rather than its current approach that simultaneously allows and questions a high degree of decentralization (both within the party and the government)?" This paper seeks to add to that intellectual discourse by applying recent data and a conceptual framework. 展开更多
关键词 policy transfer Chinese local government comparative institutions
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What Isat Stake in Comparing the Literatures?
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作者 Jose Luis Jobim 《Journal of Foreign Languages and Cultures》 2023年第1期53-64,共12页
This paper will present and discuss a few questions raised in David Damrosch's Comparing the Literatures:Literary Studies in a Global Age,a book that,divided into chapters based on some selected keywords,develops ... This paper will present and discuss a few questions raised in David Damrosch's Comparing the Literatures:Literary Studies in a Global Age,a book that,divided into chapters based on some selected keywords,develops relevant thematic nuclei,bringing to the fore literary authors,critics,and theorists. 展开更多
关键词 comparative literature TRANSLATION world literature trasnational literary experience linguistic imperialism
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Comparative transcriptome analysis between rhesus macaques(Macaca mulatta) and crab-eating macaques(M. fascicularis) 被引量:1
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作者 Yu-Xiang Mao Yamei Li +6 位作者 Zikun Yang Ning Xu Shilong Zhang Xuankai Wang Xiangyu Yang Qiang Sun Yafei Mao 《Zoological Research》 SCIE CSCD 2024年第2期299-310,共12页
Understanding gene expression variations between species is pivotal for deciphering the evolutionary diversity in phenotypes. Rhesus macaques(Macaca mulatta, MMU)and crab-eating macaques(M. fascicularis, MFA) serve as... Understanding gene expression variations between species is pivotal for deciphering the evolutionary diversity in phenotypes. Rhesus macaques(Macaca mulatta, MMU)and crab-eating macaques(M. fascicularis, MFA) serve as crucial nonhuman primate biomedical models with different phenotypes. To date, however, large-scale comparative transcriptome research between these two species has not yet been fully explored. Here, we conducted systematic comparisons utilizing newly sequenced RNA-seq data from84 samples(41 MFA samples and 43 MMU samples)encompassing 14 common tissues. Our findings revealed a small fraction of genes(3.7%) with differential expression between the two species, as well as 36.5% of genes with tissue-specific expression in both macaques. Comparison of gene expression between macaques and humans indicated that 22.6% of orthologous genes displayed differential expression in at least two tissues. Moreover,19.41% of genes that overlapped with macaque-specific structural variants showed differential expression between humans and macaques. Of these, the FAM220A gene exhibited elevated expression in humans compared to macaques due to lineage-specific duplication. In summary,this study presents a large-scale transcriptomic comparison between MMU and MFA and between macaques and humans. The discovery of gene expression variations not only enhances the biomedical utility of macaque models but also contributes to the wider field of primate genomics. 展开更多
关键词 Crab-eating macaques Rhesus macaques Comparative transcriptomics Biomedical models Nonhuman primates RNA-SEQ Duplicated genes
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超声辅助与纤维支气管镜辅助经皮扩张气管切开术的对比研究
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作者 郭龙飞 张冬泉 +1 位作者 王全红 李浩 《中国耳鼻咽喉头颈外科》 CSCD 2024年第1期63-65,共3页
目的探讨超声辅助经皮扩张气管切开术的应用价值。方法回顾性分析2020年12月~2022年12月在甘肃省人民医院重症医学科行经皮扩张气管切开术患者56例,均经口气管插管后呼吸机辅助呼吸,根据不同的辅助方式分为超声辅助(超声组)31例和纤维... 目的探讨超声辅助经皮扩张气管切开术的应用价值。方法回顾性分析2020年12月~2022年12月在甘肃省人民医院重症医学科行经皮扩张气管切开术患者56例,均经口气管插管后呼吸机辅助呼吸,根据不同的辅助方式分为超声辅助(超声组)31例和纤维支气管镜辅助(纤维支气管镜组)25例。结果与纤维支气管镜组比较,超声组术中氧合指数(PaO_(2)/FiO_(2))增高[(157.3±19.2)mmHg vs.(145.4±22.8)mmHg,t=2.117,P=0.039],分钟通气(MV)量增高[(7.3±0.8)L/min vs.(6.1±0.7)L/min,t=5.278,P<0.001],动脉血二氧化碳分压(PCO_(2))降低[(39.1±4.8)mmHgvs.(44.3±5.6)mmHg,t=-3.709,P<0.001],术后出血例数减少[0例vs.4例,χ^(2)=5.246,P=0.022]。结论超声组较纤维支气管镜组行经皮扩张气管切开术手术并发症少,安全性高。 展开更多
关键词 对比研究(Comparative Study) 超声检查(Ultrasonography) 经皮扩张气管切开术(percutaneous dilatational tracheotomy)
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低温等离子射频消融联合下鼻甲骨折外移术治疗阻塞性睡眠呼吸暂停低通气综合征的疗效观察
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作者 欧阳杰 王小琴 《中国耳鼻咽喉头颈外科》 CSCD 2024年第2期127-128,共2页
目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者接受低温等离子射频消融联合下鼻甲骨折外移术后睡眠及经鼻持续气道正压通气(nasal continuous positive airway pressure,nCPAP)治疗耐受性的改善情况。方法选择40例OSAHS合并双侧... 目的探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者接受低温等离子射频消融联合下鼻甲骨折外移术后睡眠及经鼻持续气道正压通气(nasal continuous positive airway pressure,nCPAP)治疗耐受性的改善情况。方法选择40例OSAHS合并双侧下鼻甲肥大的患者作为研究对象,均在局麻下接受下鼻甲低温等离子射频消融联合骨折外移术。术前及术后2周分别采用多导睡眠监测(PSG)、鼻阻力仪、autoCPAP呼吸机及视觉模拟量表(VAS)测定睡眠呼吸暂停低通气指数(AHI)、最低血氧饱和度(lowest oxygen saturation,LSaO_(2))、鼻气道阻力及nCPAP治疗耐受性。结果与术前比较,术后2周时患者AHI降低至(35.17±9.72)次/h,LSaO_(2)提高至(83.21±6.58)%,鼻气道阻力降低至(0.55±0.09)kPa·s/cm^(3),VAS评分升高至8.32±1.17,差异比较均有统计学意义(P均<0.05)。结论低温等离子射频消融联合下鼻甲骨折外移术能有效降低OSAHS患者的鼻阻力,提高nCPAP治疗的耐受性,改善OSAHS患者的睡眠情况。 展开更多
关键词 睡眠呼吸暂停 阻塞性(Sleep Apnea Obstructive) 外科手术(Surgical Procedures Operative) 对比研究(Comparative Study) 治疗结果(Treatment Outcome) 下鼻甲射频消融术(radiofrequency ablation of inferior turbinate)
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Comparative Orotomy of the Archean Superior,North China,and Phanerozoic Altaid Orogenic Systems Architecture
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作者 T.M.KUSKY A.M.C.ŞENGÖR 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2024年第S01期33-35,共3页
Geological maps encode vast amounts of data about rock types,ages,chemistry,orogenic architecture and deep-time history or different tectonic units,yet these are often difficult to extract because of the way different... Geological maps encode vast amounts of data about rock types,ages,chemistry,orogenic architecture and deep-time history or different tectonic units,yet these are often difficult to extract because of the way different geologists portray their results at various scales.To understand orogenesis in 4D,it is essential to uniformly integrate map data,together with geophysical data and deep geochemical mapping(Wang et al.,2023). 展开更多
关键词 ARCHEAN comparative tectonics orotomy Superior craton ALTAIDS North China craton
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Rice-wheat comparative genomics:Gains and gaps
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作者 Akila Wijerathna-Yapa Ruchi Bishnoi +11 位作者 Buddhini Ranawaka Manu Maya Magar Hafeez Ur Rehman Swati G.Bharad Michal T.Lorenc Vinita Ramtekey Sasha Gohar Charu Lata Md.Harun-Or-Rashid Maryam Razzaq Muhammad Sajjad Bhoja R.Basnet 《The Crop Journal》 SCIE CSCD 2024年第3期656-669,共14页
Rice and wheat provide nearly 40%of human calorie and protein requirements.They share a common ancestor and belong to the Poaceae(grass)family.Characterizing their genetic homology is crucial for developing new cultiv... Rice and wheat provide nearly 40%of human calorie and protein requirements.They share a common ancestor and belong to the Poaceae(grass)family.Characterizing their genetic homology is crucial for developing new cultivars with enhanced traits.Several wheat genes and gene families have been characterized based on their rice orthologs.Rice–wheat orthology can identify genetic regions that regulate similar traits in both crops.Rice–wheat comparative genomics can identify candidate wheat genes in a genomic region identified by association or QTL mapping,deduce their putative functions and biochemical pathways,and develop molecular markers for marker-assisted breeding.A knowledge of gene homology facilitates the transfer between crops of genes or genomic regions associated with desirable traits by genetic engineering,gene editing,or wide crossing. 展开更多
关键词 Comparative genomics ORTHOLOGS GENES SYNTENY Genetic engineering Molecular breeding
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Is convenience really king?Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam:a longitudinal patient cost study
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作者 Hoa Binh Nguyen Luan Nguyen Quang Vo +13 位作者 Rachel Jeanette Forse Anja Maria Christine Wiemers Huy Ba Huynh Thuy Thi Thu Dong Yen Thi Hoang Phan Jacob Creswell Thi Minh Ha Dang Lan Huu Nguyen Jad Shedrawy Knut Lönnroth Tuan Dinh Nguyen Luong Van Dinh Kristi Sidney Annerstedt Andrew James Codlin 《Infectious Diseases of Poverty》 SCIE CAS CSCD 2024年第2期17-28,共12页
Background In Viet Nam,tuberculosis(TB)represents a devastating life-event with an exorbitant price tag,partly due to lost income from daily directly observed therapy in public sector care.Thus,persons with TB may see... Background In Viet Nam,tuberculosis(TB)represents a devastating life-event with an exorbitant price tag,partly due to lost income from daily directly observed therapy in public sector care.Thus,persons with TB may seek care in the private sector for its flexibility,convenience,and privacy.Our study aimed to measure income changes,costs and catastrophic cost incurrence among TB-affected households in the public and private sector.Methods Between October 2020 and March 2022,we conducted 110 longitudinal patient cost interviews,among 50 patients privately treated for TB and 60 TB patients treated by the National TB Program(NTP)in Ha Noi,Hai Phong and Ho Chi Minh City,Viet Nam.Using a local adaptation of the WHO TB patient cost survey tool,participants were interviewed during the intensive phase,continuation phase and post-treatment.We compared income levels,direct and indirect treatment costs,catastrophic costs using Wilcoxon rank-sum and chi-squared tests and associated risk factors between the two cohorts using multivariate regression.Results The pre-treatment median monthly household income was significantly higher in the private sector versus NTP cohort(USD 868 vs USD 578;P=0.010).However,private sector treatment was also significantly costlier(USD 2075 vs USD 1313;P=0.005),driven by direct medical costs which were 4.6 times higher than costs reported by NTP participants(USD 754 vs USD 164;P<0.001).This resulted in no significant difference in catastrophic costs between the two cohorts(Private:55%vs NTP:52%;P=0.675).Factors associated with catastrophic cost included being a single-person household[adjusted odds ratio[(a OR=13.71;95%confidence interval(CI):1.36-138.14;P=0.026)],unemployment during treatment(a OR=10.86;95%CI:2.64-44.60;P<0.001)and experiencing TB-related stigma(a OR=37.90;95%CI:1.72-831.73;P=0.021)].Conclusions Persons with TB in Viet Nam face similarly high risk of catastrophic costs whether treated in the public or private sector.Patient costs could be reduced through expanded insurance reimbursement to minimize direct medical costs in the private sector,use of remote monitoring and multi-week/month dosing strategies to avert economic costs in the public sector and greater access to social protection mechanism in general. 展开更多
关键词 TUBERCULOSIS Patient cost Catastrophic cost Private sector Comparative analysis Viet Nam
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