Transforming growth factor-beta 1 enhances discharge activity of cortical neurons

Transforming growth factor-beta 1(TGF-β1)has been extensively studied for its pleiotropic effects on central nervous system diseases.The neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may depend on the pathological process and cell types involved.Voltage-gated sodium channels(VGSCs)are essential ion channels for the generation of action potentials in neurons,and are involved in various neuroexcitation-related diseases.However,the effects of TGF-β1 on the functional properties of VGSCs and firing properties in cortical neurons remain unclear.In this study,we investigated the effects of TGF-β1 on VGSC function and firing properties in primary cortical neurons from mice.We found that TGF-β1 increased VGSC current density in a dose-and time-dependent manner,which was attributable to the upregulation of Nav1.3 expression.Increased VGSC current density and Nav1.3 expression were significantly abolished by preincubation with inhibitors of mitogen-activated protein kinase kinase(PD98059),p38 mitogen-activated protein kinase(SB203580),and Jun NH2-terminal kinase 1/2 inhibitor(SP600125).Interestingly,TGF-β1 significantly increased the firing threshold of action potentials but did not change their firing rate in cortical neurons.These findings suggest that TGF-β1 can increase Nav1.3 expression through activation of the ERK1/2-JNK-MAPK pathway,which leads to a decrease in the firing threshold of action potentials in cortical neurons under pathological conditions.Thus,this contributes to the occurrence and progression of neuroexcitatory-related diseases of the central nervous system.

Swin-Transformer故障信息挖掘的海底观测网故障定位方法

海底观测网长期受海洋环境与人为因素影响,易使光电复合缆绝缘破损与海水接触形成电学故障点。如何准确地定位电学故障点,对提高海底观测网输电与信息传输的可靠性至关重要。首先根据海底观测网输电结构建立海底观测网输电模型,推导与模拟电学故障点传播至观测点的暂态电流,然后由连续小波变换提取暂态电流与故障点对应的内在关联特征量,最后通过Swin-Transformer神经网络挖掘内在关联特征量与故障距离的匹配关系来定位电学故障点。研究结果表明,在内在关联特征量样本测试集条件下,光电复合缆≤160 km的电学故障点定位误差小于400 m,可为长距离光电复合缆的海底观测网电学故障点定位提供参考。

Transformer Internal and Inrush Current Fault Detection Using Machine Learning

Preventive maintenance in the transformer is performed through a dif-ferential relay protection system,and it protects the transformer from internal and external faults.However,the Current Transformer(CT)in the differential protec-tion system mal-operates during inrush currents.CT saturates due to magnetizing inrush currents and causes false tripping of the differential relays.Moreover,iden-tification of tripping in protection relay either due to inrush current or internal faults needs to be diagnosed.For the above problem,continuous monitoring of transformer breather and CT terminals with thermal camera helps detect the trip-ping in relay due to inrush or internal fault.The transformer’s internal fault leads to high breathing process in the transformer breather,never for inrush currents.During inrush currents,CT temperature is increased.Continuous monitoring of breather and CT of the transformer through thermal imaging and radiometric pix-els detect the causes of CT saturation and differentiates maloperation.Hybrid wavelet threshold image analytics(HWT-IA)based radiometric pixels analysis of the transformer breather and CT after de-noising provides an accurate result of about 95%for identification of the false tripping of differential protection system of transformer.

Over Voltage Fault due to Disconnection of Consumer’s Transformer Neutral Wire

Practically,the load currents in three phases are asymmetric in the power system.It means that the impedances are different in all three phases.If the consumer’s transformer neutral cut off and/or was disconnected from the neutral of power supply source,then there will be some trouble and failure occurred.The current in the neutral wire drops down to zero when the neutral wire is cut off and the phase currents of all three-phase equal to each other since there was no return wire.The currents are equal but the voltages at the phase consumers are different.Especially for residential single-phase consumers,the voltage at the consumers of the phase varies differently for three phase systems when the neutral wire was disconnected at consumer side and even the voltage at the consumers one or two of those three phases becomes over nominal voltage or reaches nearly line voltage.In this case,the electronic appliances in that phase will be fed by high voltage than the rated value and they can be broken down.In the power system of UB(Ulaanbaatar)city,there are some occasional such kind of failures every year.Obviously,many electronic appliances were broken down due to high voltage and the electricity utility companies respond for service charge of damaged parts.

Optically Driven Current Transformer with Optical Fiber Data Link

An optical fiber transmitting photoelectric coupling current transformer has been developed. In the environment of high voltage and electromagnetic fields, this device is characterized by high insulation, high reliability, small mass and high anti-interference. The structure design and operating principle of the system are introduced, measurement errors are analyzed and experimental results are given.

Optical fiber-based power and data delivery system for high voltage electronic current transformer

This paper describes a prototype power delivery system developed for high voltage electronic current transformer （ECT） that uses laser light to transfer power to and communicates with the primary converter. The design is based on optical-to-electrical power converters, solid-state diode lasers and optical fibers. Command signals are transmitted via the same up-fiber used to send power from secondary power supply to primary converter. The upward data transmission is completed during the brief interruption of power delivery without affecting steady power-supply. A simple comparator added to the primary converter can take the command data. Experimental results show that the fibers can provide reliable up-link for data transmission at 200 kb/s from the secondary to the primary converter. Based on the delivery system, the secondary converter can control three auxiliary channels to provide additional information. These monitoring channels are used in a time-multiplexing mode to provide information about the operation temperature, voltage and current at the remote unit for monitoring the ECT. This preventive maintenance or built-in test can increase reliability by giving early warning for necessary maintenance request.

Investigation and Mitigation of Transformer Inrush Current during Black Start of an Independent Power Producer Plant

The energizing of large power transformers has long been considered a critical event in the operation of an electric power system. When a transformer is energized by the utility, a typical inrush current could be as high as ten times its rated current. This could cause many problems from mechanical stress on transformer windings to harmonics injection, and system protection malfunction. There have been numerous researches focusing on calculation and mitigation of the transformer inrush current. With the development of smart grid, distributed generation from independent power producers (IPPs) is growing rapidly. This paper investigates the inrush current due to black start of an IPP system with several parallel transformers, through a simulation model in DIgSILENT Power Factory software. The study demonstrates that a single genset is capable of energizing a group of transformers since the overall inrush current is slightly above the inrush of the transformer directly connected to the generator. In addition, a simple method is proposed to mitigate the inrush current of the transformers using an auxiliary transformer.

Effect of Modulation Error on All Optical Fiber Current Transformers

For actively modulated In-line Sagnac interferential all optic fiber current transformers (AOFCTs), the accuracies are directly affected by the amplitude of the modulation signal. In order to deeply undertand the function of the modulator, a theoretical model of modulation effect to AOFCTs is built up in this paper. The effect of the amplitude of the modulation signal to the output intensity of AOFCTs is theoretically formulated and numerical calculated. The results show that the modulation voltage variation could affect the output accuracies significantly. This might be some references on the investigation for practical applications of AOFCTs.

Design and applicability analysis of independent double acquisition circuit of all-fiber optical current transformer

The advantages of the all-fiber optical current transformer include but are not limited to being small in size,having no magnetic saturation,exhibiting high measurement accuracy,and boasting strong electromagnetic interference resistance.However,the high cost of the all-fiber optical transformer limits its promotion and application in engineering.This paper proposes a design scheme of an independent double acquisition loop for the all-fiber optical current transformer based on the single optical path.Firstly,based on the closed-loop control mode and open-loop control mode,the twochannel sampling signal demand for relay protection,and the independent dual-acquisition loop design scheme of the all-fiber optical current transformer are proposed.Secondly,the reliability and economic feasibility of the scheme are demonstrated by an analysis of system failure and cost.The results show that the scheme can actualize the acquisition function of two independent all-fiber optical current transformer products on a single all-fiber current transformer in an integrated manner,which greatly reduces the cost of the all-fiber optical current transformer in engineering applications.

Study of wavelet transform type high-current transformer

The wavelet transformation is applied to the high current transformer.The high current transformer elaborated in the paper is mainly applied to the measurement of AC/DC high current.The principle of the transformer is the Hall direct measurement principle.The transformer has the following three characteristics:firstly, the effect of the remnant field of the iron core on the measurement is decreased;secondly,because the temperature compensation is adopted,the transformer has good temperature charactreristic;thirdly,be cause the wavelet transfomation technology is adopted,the transformer has the capacity of good antijanming.

Alternative Approaches for Distinguishing between Faults and Inrush Current in Power Transformers

In this study, we will cover the basic methods used to distinguish between inrush current and fault current in power transformers. First, the nature of inrush current is presented compared to the fault current. Then the nature of the magnetizing current due to energizing a power transformer at no-load is explained. The first generation of methods used to disable the protective relay system during inrush current, namely the Desensitizing and Tripping Suppressor, is introduced. The second generation, the harmonic restraint method and the waveform-based restraint method with their different versions, is explained. Then we will explore thoroughly the fictitious equivalent resistance method as an example of the third generation of model type restraining or blocking methods. Finally, a comparison between these methods and conclusion is carried out.

The Discrimination of Inrush Current from Internal Fault of Power Transformer based on EMD

The method is based on that the waveform of the inrush distorts seriously, while the fault current nearly keeps sinusoid. The complicated signal can be decomposed into a finite intrinsic mode functions (IMF) by the EMD, then define and compute the projection area on X-axis of each IMF—, the specific gravity of SIMF—, and the maximum of —. We can get a new scheme of transformer-protection based on comparing the difference between inrush and fault current. Theoretical analysis show that the method can precisely discriminate inrush and fault current, fault clearance time is about 20ms. Moreover, it is convenient to achieve and hardly be affect by not-periodic component.

An active-passive beam current transformer

In this article,a new type current transformer was developed using an active-passive circuit to improve low frequency response of the system without impairing high frequency response.The active-passive current transformer with In-flange was fabricated.Theoretical analysis,numerical simulations and experimental results are given.

Analysis on the Transfer Characteristics of Rogowski-coil Current Transformer and Its Influence on Protective Relaying

This paper systematically analyzes the transfer characteristics of the Rogowski-coil Current Transformer and its effect on protective relaying through theoretical analysis, experiments and simulations. The frequency characteristics and transient characteristics of Rogowski transducer and Rogowski-coil Current Transformer are deeply analyzed based on the physical structure of the transformer.?It is revealed that broad bandwidth of the transformer can improve the performance of protective relaying, and the bandwidth is determined mainly by the parameters of the Rogowski transducer and signal processing circuits. It is also discovered that the measurement errors of transient current mainly depend on the abilities for the current transformer to reproduce an accurate replica of the decaying dc components, which is mainly decided by the decay time constant of the aperiodic component of transient current and the parameters of the integral unit. Finally, some measures are proposed for the performance improvement of Rogowski-coil Current Transformer to meet the requirements of protective relaying system in terms of structural design and testing standards.

Research on Numerical Simulation of 3D Leakage Magnetic Field and Short-circuit Impedance of Axial Dual-low-voltage Split-winding Transformer

It is difficult to accurately calculate the short-circuit impedance, due to the complexity of axial dual-low-voltage split-winding transformer winding structure. In this paper, firstly, the leakage magnetic field and short-circuit impedance model of axial dual-low-voltage split-winding transformer is established, and then the 2D and 3D leakage magnetic field are analyzed. Secondly, the short-circuit impedance and split parallel branch current distribution in different working conditions are calculated, which is based on field-circuit coupled method. At last, effectiveness and feasibility of the proposed model is verified by comparison between experiment, analysis and simulation. The results showed that the 3D analysis method is a better approach to calculate the short-circuit impedance, since its analytical value is more closer to the experimental value compared with the 2D analysis results, the finite element method calculation error is less than 2%, while the leakage flux method maximum error is 7.2%.

Calculation of Eddy Current Loss and Short-circuit Force in SSZ11-50000/110 Power Transformer

The ?method is used in this paper to calculate the leakage magnetic field of SSZ11-50000/110 Power transformer, and by which the structures’ influences to the main leakage flux are analyzed. Through the combination of the product and TEAM Problem 21B, the surface impedance method shows its great advantage in the calculation of eddy current loss.

Study on the Effect of Multi-Type Current Transformers Hybrid Operation on Differential Protection of the Bus Based on Dynamic Simulation

This paper analyzes characteristics of multi type current transformers hybrid operation for each branch of the bus and their effects on differential protection of the bus. By theoretically analyzing transmission characteristics of multi type current transformers and their influence factors, we study the dynamic model testing method of multi type current transformers for the bus, and design 3 kinds of testing schemes by making the equivalent model based on the field of P-level current transformer, TPY-level current transformer and electronic current transformer, and build the hybrid operation testing platform of multi type current transformers. Finally, we compare and analyze the transmission characteristics difference of multi type current transformers on the same branch and the characteristics difference of hybrid operation in two successive external faults, analyze the cause behind the differences, and put forward the corresponding improvement measures.

35 kV不接地系统开关柜内故障TA饱和波形分析

电流互感器饱和引起的区内故障拒动、区外故障误动在电网运行中是存在的,发生此类故障对电网和用户的影响比较严重,特别是66 kV及以下电压等级电流互感器,由于制造、成本等原因,TA饱和现象比110 kV以上电压等级普遍。本案例是一110 kV用户35 kV开关柜故障两组35 kV电流互感器先后饱和造成区内故障拒动,区外故障误动,使工厂停产,直到恢复正常供电。

Effects of Ta Addition on Microstructure and Transformation Behavior of Ni-Ti Alloys

The effect of adding Ta on the changes of microstructure and Ms temperature of a dualphase shape memory alloy with compositions of (Ni51 Ti49)1 -x.Tax. and Ni50-Ti50 -g.Ta.g were systematically studied. An optical microscope, SEM, X-ray diffraction and DSC were utilized in this work. The evolution of the microstructure as a function of Ta content was characterized. The variation of the Ni/Ti ratio in the NiTi phase plays an important role in the change of the Ms temperatures due to the addition of Ta. A pseudobinary NiTi-Ta phase diagram was proposed based on these results.