The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional e...The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional experiences but is also an important way to improve their quality of life.However,the existing research has not yet reached a clear conclusion on how tourists'sense of well-being is formed,whether tourists'sense of well-being will spill over(i.e.,knowledge sharing)after tourists obtain it,and whether the destination familiarity brought by the spillover of sense of well-being(i.e.,knowledge sharing)will affect other tourists.Therefore,based on the experience marketing theory and the embodiment theory,this paper empirically examines the formation and spillover effect of tourists'sense of well-being through structural equation modeling(SEM).The research shows that:(a)Subject presence has a positive effect on tourists'sense of well-being,which further promotes knowledge sharing and realizes the spillover of tourists'sense of well-being,and tourists'sense of well-being plays a mediating role between subject presence and knowledge sharing;(b)Destination familiarity resulting from the spillover of sense of wellbeing(i.e.,knowledge sharing)plays a negative moderating role in the positive impact of subject presence on tourists'sense of well-being.This paper not only expands the boundaries of research on tourists'sense of well-being and embodiment theory to some extent but also provides theoretical support and countermeasures for the high-quality development of China's tourism and even service industry.展开更多
The spectrum user’s librarys containing 1533 familiar toxicants have been built; A method with high separability and sensitivity has been found,The RT and the detection limit of 210 familiar abuse drugs has been conf...The spectrum user’s librarys containing 1533 familiar toxicants have been built; A method with high separability and sensitivity has been found,The RT and the detection limit of 210 familiar abuse drugs has been confirmed; the processing methods to analyse spectrum data automatically have been found; It is simple,quick,sensitive and reliable,and can take place of manual operation,It is very useful to screen the familiar toxicants in unkown sample.展开更多
Purpose This study aimed to investigate whether there is a systematic change of leg muscle activity,as quantified by surface electromyography(EMG),throughout a standard running footwear assessment protocol at a predet...Purpose This study aimed to investigate whether there is a systematic change of leg muscle activity,as quantified by surface electromyography(EMG),throughout a standard running footwear assessment protocol at a predetermined running speed.Methods Thirty-one physically active adults(15 females and 16 males)completed 5 testing rounds consisting of overground running trials at a speed of 3.5 m/s.The level of muscle activity from 6 major leg muscles was recorded using surface EMG.The variables assessed were the EMG total intensity as a function of time and the cumulative EMG overall intensity.Systematic effects of the chronological testing round(independent variable)on the normalized EMG overall intensity(dependent variable)were examined using Friedman analysis of variates and post hoc pairwise Wilcoxon signed-rank tests(α=0.05).Results There was a systematic reduction in overall EMG intensity for all 6 muscles over the time course of the running protocol(p<0.001)until the fourth testing round when EMG intensities reached a steady state.The one exception was the biceps femoris muscle,which showed a significant reduction of EMG intensity during the stance phase(p<0.001)but not the swing phase(p=0.16).Conclusion While running at a predetermined speed,the neuromuscular system undergoes an adaptation process characterized by a progressive reduction in the activity level of major leg muscles.This process may represent an optimization strategy of the neuromuscular system towards a more energetically efficient running style.Future running protocols should include a familiarization period of at least 7 min or 600 strides of running at the predetermined speed.展开更多
Based on the interactive theory of reading, this study mainly explored the etlects ot topic familiarity and second language proficiency on IVA （Incidental Vocabulary Acquisition） of second language through reading. ...Based on the interactive theory of reading, this study mainly explored the etlects ot topic familiarity and second language proficiency on IVA （Incidental Vocabulary Acquisition） of second language through reading. By using two different measures （translation production and selection）, this study found： （1） Vocabulary can be acquired incidentally in reading passages; （2） There are no significant interactive effects of topic familiarity and second language proficiency on vocabulary acquisition, but the two independent variables of topic familiarity and second language proficiency exerted their positively significant effect on incidental vocabulary acquisition, and （3） As for the two vocabulary measures, learners can acquire more words in translation selection than in translation production.展开更多
Since no language can exist in a cultural vacuum, and since no two cultures are exactly identical, second or foreign language learners will inevitably encounter cultural confrontations on their learning route. However...Since no language can exist in a cultural vacuum, and since no two cultures are exactly identical, second or foreign language learners will inevitably encounter cultural confrontations on their learning route. However, it does not mean that learners must abandon their own culture in order to avoid the potential cultural collision. What they need to do is to accumulate the knowledge pertaining to the target culture so as to develop cross-cultural awareness. This paper will draw on previous research in this arena as well as the author＇s personal knowledge to further explore the relationship between socioculture and second language acquisition from the perspectives of culture and language, cultural confrontation, and culture familiarization.展开更多
Objective To study the clinical and genetic features of familiar amyloid polyneuropathy (FAP). Methods Three families of suspected FAP in China mainland and Macao were investigated on aspects of clinical manifestation...Objective To study the clinical and genetic features of familiar amyloid polyneuropathy (FAP). Methods Three families of suspected FAP in China mainland and Macao were investigated on aspects of clinical manifestations, histological features, and gene analysis. Results All the 3 families had the clinical features of sensory and motor polyneuropathies, and notable vegetative nerve involvements. Affected cases of one family had ultrasound proved cardiomyopathy. Histological studies showed amyloid deposition in all the biopsy tissues of the affected cases of the 3 families, and anti-transthyretin antisera staining was positive in 3 cases of one family. Gene analysis confirmed that mutation types were amyloidogenic transthyretin (ATTR) Val30Met, Phe33Val, and Gly67Glu in the 3 families respectively. The ATTR Gly67Glu family had a shorter survival time due to the heart involvement compared with the other 2 families. Conclusion FAP is an autosomal dominant inherited disease, with its clinical manifestations related to the type of genetic mutation.展开更多
Objective:The aim of the study was to investigate the influence of gastric cancer family history in the gastric cancer (GC) patients. Methods: Gastric cancer family histories within second degree relatives and clinico...Objective:The aim of the study was to investigate the influence of gastric cancer family history in the gastric cancer (GC) patients. Methods: Gastric cancer family histories within second degree relatives and clinicopathological features were obtained for 497 patients. Results:Of the 497 probands,235 probands were incorporated into familial gastric cancer (FGC) group (there were at least two GC members in the family); 262 probands were included in the non-FGC group (relatives only affected with non-GCs). Of 614 tumors in relatives,GC was the most frequent,followed by lung cancer,esophageal cancer,hepatocellular cancer,colorectal cancer,urogenital cancer,breast cancer,and pancreatic cancer. Most affected members aggregated within first-degree relatives. The ratio of males to females in affected first-degree relatives was usually higher in male probands. Paternal history of GC was a strong risk for GC in males,while risk of GC by maternal history of GCs was increased in females. Difference in tumor histological types between the two groups was derived from an excess of diffuse GC in non-FGC male probands. The lower site was the most frequent tumor location in all subgroups. Conclusion:Distribution of associated non-GCs in a family history of GC may vary with geographic areas. GC may have different genetic and/or environmental etiology in different families,and a certain subtype may be inherited in a male-influenced fashion.展开更多
Several investigations have shown that emotional events show superior recall than non-emotional ones. However, the cortical mechanisms underlying the episodic recall of emotional scenes are still poorly understood. Ou...Several investigations have shown that emotional events show superior recall than non-emotional ones. However, the cortical mechanisms underlying the episodic recall of emotional scenes are still poorly understood. Our main aim was to compare the magnitude of the Event-Related brain Potentials (ERP) old-new effect related to emotionally unpleasant, pleasant and neutral photographic images. As expected, correct recognition of all types of images elicited three topographically distinct ERP components sensitive to the classical old-new recognition effect. The results revealed that the behavioral performances were mainly sensitive to arousal, while the ERP old/new effect over posterior regions (300 - 1000 ms) was exclusively affected by unpleasantness. A later component (1000 - 1400 ms) showed an inverted old/ new effect at parietal sites, which was also sensitive to unpleasantness. These results imply that ERP reflecting episodic conscious recollection and post-retrieval monitoring are clearly affected both by valence and arousal.展开更多
Emery dreifuss muscular dystrophy(EDMD) is a rare genetic syndrome consisting of tendon retractions,progressive muscle atrophy and cardiac involvement.We report a case of an obese patient affected by the familial X-li...Emery dreifuss muscular dystrophy(EDMD) is a rare genetic syndrome consisting of tendon retractions,progressive muscle atrophy and cardiac involvement.We report a case of an obese patient affected by the familial X-linked form in which a pericallosal lipoma was found during investigation for a suspected acute vasculopathy.To date,EDMD has never been associated with cerebral lipomas and the X-linked form was never considered to be involved in lipodystrophic syndromes or non-muscular conditions.Our case confirms the variable expressivity of the disease and suggests a possible role of Emerin in the intranuclear regulation of signals for adipocyte cell differentiation.展开更多
Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM...Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely展开更多
This study examines the factors that affect the performance of foreign acquiring firms in Chinese M＆As （mergers and acquisitions） market. Comparing between overseas Sino-Group and Anglo-Group, this study found that...This study examines the factors that affect the performance of foreign acquiring firms in Chinese M＆As （mergers and acquisitions） market. Comparing between overseas Sino-Group and Anglo-Group, this study found that familiarity and location were the most important factors influencing performance of M＆A transactions in China. It also found that unrelated M＆A deals should be merged with familiarity for gaining positive acquisition performance. The total sample used in this study was 3,442 cases from October 1980 to March 2005. Because this period included all deals of M＆As after the opening of Chinese market in China. The authors＇ finding provided a more universal explanation in the cross-border M＆As in China.展开更多
基金supported by the Sichuan Social Science Planning Project (General Project)“Research on the Development of Rural Tourism Sharing Economy in Sichuan from the Perspective of Rural Revitalization Strategy and All-for-one Tourism” (SC20B133)the Humanities and Social Sciences Research Special Fund Cultivation Project (2022-2023RW021)of Southwest Petroleum University。
文摘The high-quality development of tourism aims to improve tourists'sense of well-being and fulfillment.The improvement of tourists'sense of well-being will not only enable tourists to obtain positive emotional experiences but is also an important way to improve their quality of life.However,the existing research has not yet reached a clear conclusion on how tourists'sense of well-being is formed,whether tourists'sense of well-being will spill over(i.e.,knowledge sharing)after tourists obtain it,and whether the destination familiarity brought by the spillover of sense of well-being(i.e.,knowledge sharing)will affect other tourists.Therefore,based on the experience marketing theory and the embodiment theory,this paper empirically examines the formation and spillover effect of tourists'sense of well-being through structural equation modeling(SEM).The research shows that:(a)Subject presence has a positive effect on tourists'sense of well-being,which further promotes knowledge sharing and realizes the spillover of tourists'sense of well-being,and tourists'sense of well-being plays a mediating role between subject presence and knowledge sharing;(b)Destination familiarity resulting from the spillover of sense of wellbeing(i.e.,knowledge sharing)plays a negative moderating role in the positive impact of subject presence on tourists'sense of well-being.This paper not only expands the boundaries of research on tourists'sense of well-being and embodiment theory to some extent but also provides theoretical support and countermeasures for the high-quality development of China's tourism and even service industry.
文摘The spectrum user’s librarys containing 1533 familiar toxicants have been built; A method with high separability and sensitivity has been found,The RT and the detection limit of 210 familiar abuse drugs has been confirmed; the processing methods to analyse spectrum data automatically have been found; It is simple,quick,sensitive and reliable,and can take place of manual operation,It is very useful to screen the familiar toxicants in unkown sample.
基金The authors would like to acknowledge Jordyn Vienneau,Aimee(Smith)Mears,Christian Meyer,and Antonio Blago for their support in collecting data for this study.The authors would like to thank Adidas(Herzogenaurach,Germany)for providing the test shoes.
文摘Purpose This study aimed to investigate whether there is a systematic change of leg muscle activity,as quantified by surface electromyography(EMG),throughout a standard running footwear assessment protocol at a predetermined running speed.Methods Thirty-one physically active adults(15 females and 16 males)completed 5 testing rounds consisting of overground running trials at a speed of 3.5 m/s.The level of muscle activity from 6 major leg muscles was recorded using surface EMG.The variables assessed were the EMG total intensity as a function of time and the cumulative EMG overall intensity.Systematic effects of the chronological testing round(independent variable)on the normalized EMG overall intensity(dependent variable)were examined using Friedman analysis of variates and post hoc pairwise Wilcoxon signed-rank tests(α=0.05).Results There was a systematic reduction in overall EMG intensity for all 6 muscles over the time course of the running protocol(p<0.001)until the fourth testing round when EMG intensities reached a steady state.The one exception was the biceps femoris muscle,which showed a significant reduction of EMG intensity during the stance phase(p<0.001)but not the swing phase(p=0.16).Conclusion While running at a predetermined speed,the neuromuscular system undergoes an adaptation process characterized by a progressive reduction in the activity level of major leg muscles.This process may represent an optimization strategy of the neuromuscular system towards a more energetically efficient running style.Future running protocols should include a familiarization period of at least 7 min or 600 strides of running at the predetermined speed.
文摘Based on the interactive theory of reading, this study mainly explored the etlects ot topic familiarity and second language proficiency on IVA （Incidental Vocabulary Acquisition） of second language through reading. By using two different measures （translation production and selection）, this study found： （1） Vocabulary can be acquired incidentally in reading passages; （2） There are no significant interactive effects of topic familiarity and second language proficiency on vocabulary acquisition, but the two independent variables of topic familiarity and second language proficiency exerted their positively significant effect on incidental vocabulary acquisition, and （3） As for the two vocabulary measures, learners can acquire more words in translation selection than in translation production.
文摘Since no language can exist in a cultural vacuum, and since no two cultures are exactly identical, second or foreign language learners will inevitably encounter cultural confrontations on their learning route. However, it does not mean that learners must abandon their own culture in order to avoid the potential cultural collision. What they need to do is to accumulate the knowledge pertaining to the target culture so as to develop cross-cultural awareness. This paper will draw on previous research in this arena as well as the author＇s personal knowledge to further explore the relationship between socioculture and second language acquisition from the perspectives of culture and language, cultural confrontation, and culture familiarization.
文摘Objective To study the clinical and genetic features of familiar amyloid polyneuropathy (FAP). Methods Three families of suspected FAP in China mainland and Macao were investigated on aspects of clinical manifestations, histological features, and gene analysis. Results All the 3 families had the clinical features of sensory and motor polyneuropathies, and notable vegetative nerve involvements. Affected cases of one family had ultrasound proved cardiomyopathy. Histological studies showed amyloid deposition in all the biopsy tissues of the affected cases of the 3 families, and anti-transthyretin antisera staining was positive in 3 cases of one family. Gene analysis confirmed that mutation types were amyloidogenic transthyretin (ATTR) Val30Met, Phe33Val, and Gly67Glu in the 3 families respectively. The ATTR Gly67Glu family had a shorter survival time due to the heart involvement compared with the other 2 families. Conclusion FAP is an autosomal dominant inherited disease, with its clinical manifestations related to the type of genetic mutation.
基金Supported by two grants from the Science and Technology Program of Shenyang (No.1071166-9-00 and No.1081232-1-00)
文摘Objective:The aim of the study was to investigate the influence of gastric cancer family history in the gastric cancer (GC) patients. Methods: Gastric cancer family histories within second degree relatives and clinicopathological features were obtained for 497 patients. Results:Of the 497 probands,235 probands were incorporated into familial gastric cancer (FGC) group (there were at least two GC members in the family); 262 probands were included in the non-FGC group (relatives only affected with non-GCs). Of 614 tumors in relatives,GC was the most frequent,followed by lung cancer,esophageal cancer,hepatocellular cancer,colorectal cancer,urogenital cancer,breast cancer,and pancreatic cancer. Most affected members aggregated within first-degree relatives. The ratio of males to females in affected first-degree relatives was usually higher in male probands. Paternal history of GC was a strong risk for GC in males,while risk of GC by maternal history of GCs was increased in females. Difference in tumor histological types between the two groups was derived from an excess of diffuse GC in non-FGC male probands. The lower site was the most frequent tumor location in all subgroups. Conclusion:Distribution of associated non-GCs in a family history of GC may vary with geographic areas. GC may have different genetic and/or environmental etiology in different families,and a certain subtype may be inherited in a male-influenced fashion.
文摘Several investigations have shown that emotional events show superior recall than non-emotional ones. However, the cortical mechanisms underlying the episodic recall of emotional scenes are still poorly understood. Our main aim was to compare the magnitude of the Event-Related brain Potentials (ERP) old-new effect related to emotionally unpleasant, pleasant and neutral photographic images. As expected, correct recognition of all types of images elicited three topographically distinct ERP components sensitive to the classical old-new recognition effect. The results revealed that the behavioral performances were mainly sensitive to arousal, while the ERP old/new effect over posterior regions (300 - 1000 ms) was exclusively affected by unpleasantness. A later component (1000 - 1400 ms) showed an inverted old/ new effect at parietal sites, which was also sensitive to unpleasantness. These results imply that ERP reflecting episodic conscious recollection and post-retrieval monitoring are clearly affected both by valence and arousal.
文摘Emery dreifuss muscular dystrophy(EDMD) is a rare genetic syndrome consisting of tendon retractions,progressive muscle atrophy and cardiac involvement.We report a case of an obese patient affected by the familial X-linked form in which a pericallosal lipoma was found during investigation for a suspected acute vasculopathy.To date,EDMD has never been associated with cerebral lipomas and the X-linked form was never considered to be involved in lipodystrophic syndromes or non-muscular conditions.Our case confirms the variable expressivity of the disease and suggests a possible role of Emerin in the intranuclear regulation of signals for adipocyte cell differentiation.
基金the funds of "the Youth Fund of Nantong Health Bureau 2015",ID:WQ2015009
文摘Dilated cardiomyopathy（DCM）is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely
文摘This study examines the factors that affect the performance of foreign acquiring firms in Chinese M＆As （mergers and acquisitions） market. Comparing between overseas Sino-Group and Anglo-Group, this study found that familiarity and location were the most important factors influencing performance of M＆A transactions in China. It also found that unrelated M＆A deals should be merged with familiarity for gaining positive acquisition performance. The total sample used in this study was 3,442 cases from October 1980 to March 2005. Because this period included all deals of M＆As after the opening of Chinese market in China. The authors＇ finding provided a more universal explanation in the cross-border M＆As in China.
