AIM: To explore the association between serum α-Lfucosidase(Af U) and non-alcoholic fatty liver disease(NAf LD).METHODS: A total of 16473 individuals(9456 men and 7017 women) were included in the current study, who p...AIM: To explore the association between serum α-Lfucosidase(Af U) and non-alcoholic fatty liver disease(NAf LD).METHODS: A total of 16473 individuals(9456 men and 7017 women) were included in the current study, who presented for a health examination at the first Affiliated hospital of Zhejiang University School of medicine in 2014. The baseline characteristics of the cohort were compared by NAf LD status. Linear regression analysis and stepwise multiple regression analysis were applied to assess the risk factors for NAf LD. Receiver operating characteristic curve was used to determine the sensitivity and specificity of Af U in the diagnosis of NAf LD.RESULTS: The prevalence rates of NAf LD and metabolic syndrome(met S) were 38.0% and 25.4%, respectively. The NAf LD group had significantly higher Af U levels than the non-NAf LD group(28.7 ± 7.9 U/L vs 26.0 ± 7.3 U/L, P < 0.001) and the prevalence rate of NAf LD increased with progressively higher serum Af U levels. Af U was positively correlated with met S and its five components: central obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol, and elevated blood pressure and fasting glucose. Stepwise multiple logistic regression analysis showed that Af U was associated with an increased risk of NAf LD(OR = 1.009, 95%CI: 1.003-1.014, P < 0.001). The best cut-off value of Af U for the diagnosis of NAf LD was 27.5 U/L. The area under the curve(diagnostic efficacy index) was 0.606. The sensitivity and specificity were 54.6% and 61.8%, respectively. CONCLUSION: Af U level is significantly associated with NAf LD, and elevated Af U level is an independent risk factor for NAf LD.展开更多
Lα, Lβ, and Lγ X-ray fluorescence cross sections for Ho and Yb have been measured at various incident photon energies in the energy range 16.04 ≤ E ≤ 24.68 keV. The measurements have been done using an X-ray tube...Lα, Lβ, and Lγ X-ray fluorescence cross sections for Ho and Yb have been measured at various incident photon energies in the energy range 16.04 ≤ E ≤ 24.68 keV. The measurements have been done using an X-ray tube with a secondary-excitor system of Zr, Nb, Mo, Cd, and In. The experimental values of the cross-sections were determined by measuring the absolute yield of L subshell X-rays emitted from a standard target of a given energy. Theoretical tabulated values of subshell photoionization cross-sections, fluorescence yields, Coster-Kronig transition probabilities and radioactive decay rates have been used to calculate the theoretical values of the cross-sections. The experimental results of the cross-sections at various excitation energies have been compared with theoretically calculated values. Fairly good agreement is obtained between the present experimental results and the calculated values.展开更多
We have studied excitation of multilevel Na-Rydberg atom due to collision with proton in the presence of variable laser field. The interaction of laser field and Na-Rydberg atom is explored using non perturbative Floq...We have studied excitation of multilevel Na-Rydberg atom due to collision with proton in the presence of variable laser field. The interaction of laser field and Na-Rydberg atom is explored using non perturbative Floquet technique. The transition probability is calculated at different laser frequencies (GHz), projectile velocities and impact-parameter. We have also calculated total cross-section for near resonant energy transfer collision of proton with Na-Rydberg atom at different frequencies.展开更多
基金Supported by National Key Basic Research Development ProgramNo.2012CB524905+9 种基金National Science and Technology Support Plan ProjectNo.2012BAI06B04National Natural Science Foundation of ChinaNo.81100278No.81170378No.81230012 and No.81270487International Science and Technology Cooperation Projects of Zhejiang ProvinceNo.2013C24010Science Fund of Health Bureau of Zhejiang ProvinceNo.2012RCA026
文摘AIM: To explore the association between serum α-Lfucosidase(Af U) and non-alcoholic fatty liver disease(NAf LD).METHODS: A total of 16473 individuals(9456 men and 7017 women) were included in the current study, who presented for a health examination at the first Affiliated hospital of Zhejiang University School of medicine in 2014. The baseline characteristics of the cohort were compared by NAf LD status. Linear regression analysis and stepwise multiple regression analysis were applied to assess the risk factors for NAf LD. Receiver operating characteristic curve was used to determine the sensitivity and specificity of Af U in the diagnosis of NAf LD.RESULTS: The prevalence rates of NAf LD and metabolic syndrome(met S) were 38.0% and 25.4%, respectively. The NAf LD group had significantly higher Af U levels than the non-NAf LD group(28.7 ± 7.9 U/L vs 26.0 ± 7.3 U/L, P < 0.001) and the prevalence rate of NAf LD increased with progressively higher serum Af U levels. Af U was positively correlated with met S and its five components: central obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol, and elevated blood pressure and fasting glucose. Stepwise multiple logistic regression analysis showed that Af U was associated with an increased risk of NAf LD(OR = 1.009, 95%CI: 1.003-1.014, P < 0.001). The best cut-off value of Af U for the diagnosis of NAf LD was 27.5 U/L. The area under the curve(diagnostic efficacy index) was 0.606. The sensitivity and specificity were 54.6% and 61.8%, respectively. CONCLUSION: Af U level is significantly associated with NAf LD, and elevated Af U level is an independent risk factor for NAf LD.
文摘Lα, Lβ, and Lγ X-ray fluorescence cross sections for Ho and Yb have been measured at various incident photon energies in the energy range 16.04 ≤ E ≤ 24.68 keV. The measurements have been done using an X-ray tube with a secondary-excitor system of Zr, Nb, Mo, Cd, and In. The experimental values of the cross-sections were determined by measuring the absolute yield of L subshell X-rays emitted from a standard target of a given energy. Theoretical tabulated values of subshell photoionization cross-sections, fluorescence yields, Coster-Kronig transition probabilities and radioactive decay rates have been used to calculate the theoretical values of the cross-sections. The experimental results of the cross-sections at various excitation energies have been compared with theoretically calculated values. Fairly good agreement is obtained between the present experimental results and the calculated values.
文摘We have studied excitation of multilevel Na-Rydberg atom due to collision with proton in the presence of variable laser field. The interaction of laser field and Na-Rydberg atom is explored using non perturbative Floquet technique. The transition probability is calculated at different laser frequencies (GHz), projectile velocities and impact-parameter. We have also calculated total cross-section for near resonant energy transfer collision of proton with Na-Rydberg atom at different frequencies.