Partial Time-Varying Coefficient Regression and Autoregressive Mixed Model

Regression and autoregressive mixed models are classical models used to analyze the relationship between time series response variable and other covariates. The coefficients in traditional regression and autoregressive mixed models are constants. However, for complicated data, the coefficients of covariates may change with time. In this article, we propose a kind of partial time-varying coefficient regression and autoregressive mixed model and obtain the local weighted least-square estimators of coefficient functions by the local polynomial technique. The asymptotic normality properties of estimators are derived under regularity conditions, and simulation studies are conducted to empirically examine the finite-sample performances of the proposed estimators. Finally, we use real data about Lake Shasta inflow to illustrate the application of the proposed model.

Partial Time-Varying Coefficient Regression and Autoregressive Mixed Model

Regression and autoregressive mixed models are classical models used to analyze the relationship between time series response variable and other covariates. The coefficients in traditional regression and autoregressive mixed models are constants. However, for complicated data, the coefficients of covariates may change with time. In this article, we propose a kind of partial time-varying coefficient regression and autoregressive mixed model and obtain the local weighted least-square estimators of coefficient functions by the local polynomial technique. The asymptotic normality properties of estimators are derived under regularity conditions, and simulation studies are conducted to empirically examine the finite-sample performances of the proposed estimators. Finally, we use real data about Lake Shasta inflow to illustrate the application of the proposed model.

Efficient Shrinkage Estimation about the Partially Linear Varying Coefficient Model with Random Effect for Longitudinal Data

In this paper, an efficient shrinkage estimation procedure for the partially linear varying coefficient model (PLVC) with random effect is considered. By selecting the significant variable and estimating the nonzero coefficient, the model structure specification is accomplished by introducing a novel penalized estimating equation. Under some mild conditions, the asymptotic properties for the proposed model selection and estimation results, such as the sparsity and oracle property, are established. Some numerical simulation studies and a real data analysis are presented to examine the finite sample performance of the procedure.

MODEL SELECTION METHOD BASED ON MAXIMAL INFORMATION COEFFICIENT OF RESIDUALS

The traditional model selection criterions try to make a balance between fitted error and model complexity. Assumptions on the distribution of the response or the noise, which may be misspecified, should be made before using the traditional ones. In this ar- ticle, we give a new model selection criterion, based on the assumption that noise term in the model is independent with explanatory variables, of minimizing the association strength between regression residuals and the response, with fewer assumptions. Maximal Information Coe^cient （MIC）, a recently proposed dependence measure, captures a wide range of associ- ations, and gives almost the same score to different type of relationships with equal noise, so MIC is used to measure the association strength. Furthermore, partial maximal information coefficient （PMIC） is introduced to capture the association between two variables removing a third controlling random variable. In addition, the definition of general partial relationship is given.

Stability analysis of concrete gravity dam on complicated foundation with multiple slide planes

A key problem in gravity dam design is providing enough stability to prevent slide, and the difficulty increases if there are several weak structural planes in the dam foundation. Overload and material weakening were taken into account, and a .finite difference strength reserve method with partial safety factors based on the reliability method was developed and used to study the anti-slide stability of a concrete gravity dam on a complicated foundation with multiple slide planes. Possible slide paths were obtained, and the stability of the foundation with possible failure planes was evaluated through analysis of the stress distribution characteristics. The results reveal the mechanism and process of sliding due to weak structural planes and their deformations, and provide a reference for anti-slide stability analysis of gravity dams in complicated geological conditions.

Comparing Land Degradation and Regeneration Trends in China Drylands

The aim of this paper is to offer a statistically sound method to make a precise account of the speed of land degradation and regeneration processes.Most common analyses of land degradation focus instead on the extent of degraded areas,rather than on the intensity of degradation processes.The study was implemented for the Potential Extent of Desertification in China(PEDC),composed by arid,semi-arid,and dry sub-humid regions and refers to the period 2002 to 2012.The metrics were standard partial regression coefficients from stepwise regressions,fitted using Net Primary Productivity as the dependent variable,and year number and aridity as predictors.The results indicate that:①the extension of degrading lands(292896 km 2 or 9.12%of PEDC)overcomes the area that is recovering(194560 km 2 or 6.06%of PEDC);and②the intensity of degrading trends is lower than that of increasing trends in three land cover types(grassland,desert,and crops)and in two aridity levels(semi-arid and dry sub-humid).Such an outcome might pinpoint restoration policies by the Chinese government,and document a possible case of hysteresis.

AR Model Based on Time Series Modeling for Predicting Egg Market Price in 2021

Eggs,as a meat consumer product in China,are closely related to the vegetable basket project.Exploring and predicting the future trend of egg market price is of great significance for stabilizing egg price and market supply.In this study,the time series AR model was used for fitting the egg market prices in the 66 d from January 1 to March 7,2021,and the delay operator nlag18 was used for white noise test,giving pr>probability of chisq<0.005.The time series was not a white noise series,and then the stationary series was used for modeling.The optimal model was selected as the AR series(BIC(3,0)),and finally,the egg market price model AM was obtained as X_(t)=9.0556+(1+0.8926)ε_(t),which was the optimal model.The model showed that the egg price fluctuations in 2021 will be clustered,and the later price will be significantly affected by external factors in the previous period.The dynamic prediction results of the model showed that the egg price would stop falling in March 2020,and the egg price would continue to slow down in March.

Parameter Sensitivity and Qualitative Analysis of Dynamics of Ovarian Tumor Growth Model with Treatment Strategy

In this paper, we are interested to find the most sensitive parameter, local and global stability of ovarian tumor growth model. For sensitivity analysis, we use Latin Hypercube Sampling (LHS) method to generate sample points and Partial Rank Correlation Coefficient (PRCC) method, uses those sample points to find out which parameters are important for the model. Based on our findings, we suggest some treatment strategies. We investigate the sensitivity of the parameters for tumor volume, y, cell nutrient density, Q and maximum tumor size, ymax. We also use Scatter Plot method using LHS samples to show the consistency of the results obtained by using PRCC. Moreover, we discuss the qualitative analysis of ovarian tumor growth model investigating the local and global stability.

Recent Progress in the Lp Theory for Elliptic and Parabolic Equations with Discontinuous Coefficients

In this paper,we review some results over the last 10-15 years on elliptic and parabolic equations with discontinuous coefficients.We begin with an approach given by N.V.Krylov to parabolic equations in the whole space with VMOx coefficients.We then discuss some subsequent development including elliptic and parabolic equations with coefficients which are allowed to be merely measurable in one or two space directions,weighted Lp estimates with Muckenhoupt(Ap)weights,non-local elliptic and parabolic equations,as well as fully nonlinear elliptic and parabolic equations.

A statistical procedure to assess the significance level of barriers to gene flow

Although several methods are available to study the extent of isolation by distance （IBD） among natural populations, comparatively few exist to detect the presence of sharp genetic breaks in genetic distance datasets. In recent years, Monmonier＇s maximum-difference algorithm has been increasingly used by population geneticists. However, this method does not provide means to measure the statistical significance of such barriers, nor to determine their relative contribution to population differentiation with respect to IBD. Here, we propose an approach to assess the significance of genetic boundaries. The method is based on the calculation of a multiple regression from distance matrices, where binary matrices represent putative genetic barriers to test, in addition to geographic and genetic distances. Simulation results suggest that this method reliably detects the presence of genetic barriers, even in situations where IBD is also significant. We also illustrate the methodology by analyzing previously published datasets. Conclusions about the importance of genetic barriers can be misleading if one does not take into consideration their relative contribution to the overall genetic structure of species.

Global sensitivity analysis of a single-cell HBV model for viral dynamics in the liver

The predictive accuracy of mathematical models representing anything ranging from the meteorological to the biological system profoundly depends on the quality of model parameters derived from experimental data.Hence,robust sensitivity analysis(SA)of these critical model parameters aids in sifting the influential from the negligible out of typically vast parameter regimes,thus illuminating key components of the system under study.We here move beyond traditional local sensitivity analysis to the adoption of global SA techniques.Partial rank correlation coefficient(PRCC)based on Latin hypercube sampling is compared with the variance-based Sobol method.We selected for this SA investigation an infection model for the hepatitis-B virus(HBV)that describes infection dynamics and clearance of HBV in the liver[Murray&Goyal,2015].The model tracks viral particles such as the tenacious and nearly ineradicable covalently closed circular DNA(cccDNA)embedded in infected nuclei and an HBV protein known as p36.Our application of these SA methods to the HBV model illuminates,especially over time,the quantitative relationships between cccDNA synthesis rate and p36 synthesis and export.Our results reinforce previous observations that the viral protein,p36,is by far the most influential factor for cccDNA replication.Moreover,both methods are capable of finding crucial parameters of the model.Though the Sobol method is independent of model structure(e.g.,linearity and monotonicity)and well suited for SA,our results ensure that LHS-PRCC suffices for SA of a non-linear model if it is monotonic.