Objective: To explore the effect and pharmacological mechanism of Xiaoyu Zhixue Tablet (XZT). Methods: XZT mainly composed of Chinese medical herbs to replenish Qi and remove stasis was used to treat patients with idi...Objective: To explore the effect and pharmacological mechanism of Xiaoyu Zhixue Tablet (XZT). Methods: XZT mainly composed of Chinese medical herbs to replenish Qi and remove stasis was used to treat patients with idiopathic multifocal bleeding and platelet aggregation defect. Patients were divided into 2 groups, the TCM group (104 cases) treated with XZT, and the control group (84 cases) with vitamin C, K and P, adrenosin and/or artificial menstruation, for at least 4 months. Results: The hemostatic effective rate was 92. 3 % in the TCM group and 27. 4 % in the control group (P < 0. 005), the recovery rate of platelet aggregation after 6 months' therapy was 69. 2 % and only 1. 8% respectively. The difference between the two groups was very significant (P < 0. 005). Conclusion: XZT could regulate the hemostatic action and platelet aggregation展开更多
文摘Objective: To explore the effect and pharmacological mechanism of Xiaoyu Zhixue Tablet (XZT). Methods: XZT mainly composed of Chinese medical herbs to replenish Qi and remove stasis was used to treat patients with idiopathic multifocal bleeding and platelet aggregation defect. Patients were divided into 2 groups, the TCM group (104 cases) treated with XZT, and the control group (84 cases) with vitamin C, K and P, adrenosin and/or artificial menstruation, for at least 4 months. Results: The hemostatic effective rate was 92. 3 % in the TCM group and 27. 4 % in the control group (P < 0. 005), the recovery rate of platelet aggregation after 6 months' therapy was 69. 2 % and only 1. 8% respectively. The difference between the two groups was very significant (P < 0. 005). Conclusion: XZT could regulate the hemostatic action and platelet aggregation