Background Traditional Chinese medicine (TCM), especially herbal medicine, has been widely used in China and now is also being increasingly used in other countries for the treatment of cardiovascular diseases. Althoug...Background Traditional Chinese medicine (TCM), especially herbal medicine, has been widely used in China and now is also being increasingly used in other countries for the treatment of cardiovascular diseases. Although many studies have demonstrated that certain Chinese herbal products are effective and safe for the treatment of cardiovascular diseases, most of these lack sufficient quality. Therefore, large randomized clinical trials and further scientific research to determine its safety, effectiveness are necessary.QiShen YiQi Dripping Pills (QSYQDP) is a herbal preparation clinically used in the treatment and prevention of coronary artery disease. Preliminary observations have shown its safety and effectiveness. Methods/Design This randomized, controlled trial will recruit 3600 patients with a history of myocardial infarction. Patients will be randomized into two groups by a Centr-Randomized System. One group receives QSYQDP, the other group receive aspirin. This trial protocol will describe eligibility criteria, detailed information on the treatment definition, blinding, endpoints, statistical methods, sample size determination, data management, legal aspects, and the current status of the trial. Discussion This trial is one of the first randomized, controlled clinical trial to evaluate the efficacy and safety of traditional Chinese herbal medicine in the treatment and secondary prevention of coronary artery disease. The results of this study should help to define the role of TCM in modern medical care, as well as to provide the management strategy for CAD patients in China and other countries.展开更多
Chinese coronary secondary prevention study （CCSPS） is a key project in the field of medicine of the Ninth Five-year Plan of China, and is also called the Study of Xuezhikang Capsule （血脂康胶囊, XZK）in regulating...Chinese coronary secondary prevention study （CCSPS） is a key project in the field of medicine of the Ninth Five-year Plan of China, and is also called the Study of Xuezhikang Capsule （血脂康胶囊, XZK）in regulating blood lipids for secondary prevention of coronary heart diseases .Since the results of the study was publicized in June 2004 at the news release and deliberation by experts took place in the Great Hall of the People in Beijing, wide attention and high opinions have been gotten, and at the same time,展开更多
Hypertensive ex—perimental studies pre—vented and treated byTCM are matured re|e—rant studies of westernmedicine for reference,such as the hypotensiveeffect and elucidating itstherapeutic mechanism.Comprehension in...Hypertensive ex—perimental studies pre—vented and treated byTCM are matured re|e—rant studies of westernmedicine for reference,such as the hypotensiveeffect and elucidating itstherapeutic mechanism.Comprehension in allliteratures,most simpleherbs and compound展开更多
This paper deals mainly with etiology, pathology, sympotomatology, harmfulness, preventive measures and treatment of larval mycosis (caused by Lagenidium sp. ) and of ciliate disease (caused by Zoothamnium sp. ) of pe...This paper deals mainly with etiology, pathology, sympotomatology, harmfulness, preventive measures and treatment of larval mycosis (caused by Lagenidium sp. ) and of ciliate disease (caused by Zoothamnium sp. ) of penaeid shrimp larvae.展开更多
Atrial fibrillation (AF) is a kind of common arrhythmia, which, besides affecting cardiac function, has another serious outcome, that is, it is easy to form atrial thrombosis and induce thrombus/embolus, especially ce...Atrial fibrillation (AF) is a kind of common arrhythmia, which, besides affecting cardiac function, has another serious outcome, that is, it is easy to form atrial thrombosis and induce thrombus/embolus, especially cerebral embolus. The incidence of left atrial thrombosis ( LAT) could reach 25% - 30%(1) , the incidence of embol-展开更多
Objective To observe the preventive effect of continuous irrigation with sodium hyaluronate injection from peridural adhesionaminectomy.Methods Larninectomies were performed in L1,L4,L7 of 25 New Zealand rabbits respe...Objective To observe the preventive effect of continuous irrigation with sodium hyaluronate injection from peridural adhesionaminectomy.Methods Larninectomies were performed in L1,L4,L7 of 25 New Zealand rabbits respectively with 3展开更多
Objective:To assess the efficacy of chlorophyl lderivative（CPD4）-Photodynamic therapy（PDT）in preventing postoperative recurrence of the in filtrativecancer of the urinary bladder-Methods:32 patients were treated w...Objective:To assess the efficacy of chlorophyl lderivative（CPD4）-Photodynamic therapy（PDT）in preventing postoperative recurrence of the in filtrativecancer of the urinary bladder-Methods:32 patients were treated with CPD4-PDT postoperationally to prevent therecurrence of can cerall of which being followedup.Results:There currenc erate was42.1%inT2 tumors and 69.2%inT3 tumors（P＜0.05）,and the survival period without tumor has been 19.8±14.8months in T2 tumors,and 22.67±19.72months in T3 tumors（P＞0.05）.There was verysignificant difference inrecurrent rate between grade I and gradeⅡ、Ⅲpatients（0%and66.7%,P<0.001）.ConcIusion:CPD4-PDT is a safe and effectiv emeasureto prevent the recurrence in infiltrative bladder cancer after operation.展开更多
Objective: To study the inhibitory effect of Radix Salviae Miltiorrhizae (RSM) on adhesive and invasive ability of SMMC 7721 liver cancer cells, and on the metastasis and recurrence on post hepatectomy liver cancer ...Objective: To study the inhibitory effect of Radix Salviae Miltiorrhizae (RSM) on adhesive and invasive ability of SMMC 7721 liver cancer cells, and on the metastasis and recurrence on post hepatectomy liver cancer in nude mice. Methods: Effect of RSM on SMMC 7721 cell membrane intercellular adhesive molecule 1 (ICAM 1) expression was observed by immunofluorescence flow cytometry; effect on invasive ability and of SMMC 7721 cell and the detachment of which attached to fibronectin (FN) by cell migration experiment; effect on adhesion of SMMC 7721 cell with FN by MTT method and effect on adhesion between 7721 7721, 7721 lymphocyte and 7721 endothelial cell by cell adhesion experiment. LCI D20 human liver cancer metastasis model, after hepatectomy, was used to observe the effect of RSM on recurrence and metastasis of liver carcinoma in nude mice. Results: ICAM 1 expression in SMMC 7721 cells incubated with RSM was significantly lower than that in cells did not treated with RSM. RSM could inhibit the invasive ability of SMMC 7721 cell and made the cells already attached to FN exfoliated. It could also inhibit the adhesion of 7721 7721, 7721 lymphocyte and 7721 endothelial cell. And RSM showed preventive and therapeutic effect on intrahepatic and remote metastasis/recurrence of early and late human post hepatectomy liver cancer in nude mice. Conclusion: RSM could inhibit the invasion and adhesion of SMMC 7721 cell and could also prevent and inhibit metastasis and recurrence of human liver cancer after hepatectomy in nude mice.展开更多
文摘Background Traditional Chinese medicine (TCM), especially herbal medicine, has been widely used in China and now is also being increasingly used in other countries for the treatment of cardiovascular diseases. Although many studies have demonstrated that certain Chinese herbal products are effective and safe for the treatment of cardiovascular diseases, most of these lack sufficient quality. Therefore, large randomized clinical trials and further scientific research to determine its safety, effectiveness are necessary.QiShen YiQi Dripping Pills (QSYQDP) is a herbal preparation clinically used in the treatment and prevention of coronary artery disease. Preliminary observations have shown its safety and effectiveness. Methods/Design This randomized, controlled trial will recruit 3600 patients with a history of myocardial infarction. Patients will be randomized into two groups by a Centr-Randomized System. One group receives QSYQDP, the other group receive aspirin. This trial protocol will describe eligibility criteria, detailed information on the treatment definition, blinding, endpoints, statistical methods, sample size determination, data management, legal aspects, and the current status of the trial. Discussion This trial is one of the first randomized, controlled clinical trial to evaluate the efficacy and safety of traditional Chinese herbal medicine in the treatment and secondary prevention of coronary artery disease. The results of this study should help to define the role of TCM in modern medical care, as well as to provide the management strategy for CAD patients in China and other countries.
文摘Chinese coronary secondary prevention study （CCSPS） is a key project in the field of medicine of the Ninth Five-year Plan of China, and is also called the Study of Xuezhikang Capsule （血脂康胶囊, XZK）in regulating blood lipids for secondary prevention of coronary heart diseases .Since the results of the study was publicized in June 2004 at the news release and deliberation by experts took place in the Great Hall of the People in Beijing, wide attention and high opinions have been gotten, and at the same time,
文摘Hypertensive ex—perimental studies pre—vented and treated byTCM are matured re|e—rant studies of westernmedicine for reference,such as the hypotensiveeffect and elucidating itstherapeutic mechanism.Comprehension in allliteratures,most simpleherbs and compound
文摘This paper deals mainly with etiology, pathology, sympotomatology, harmfulness, preventive measures and treatment of larval mycosis (caused by Lagenidium sp. ) and of ciliate disease (caused by Zoothamnium sp. ) of penaeid shrimp larvae.
基金This project is supported by Guangdong Provincial Ad-ministration of TCM(No.99592)
文摘Atrial fibrillation (AF) is a kind of common arrhythmia, which, besides affecting cardiac function, has another serious outcome, that is, it is easy to form atrial thrombosis and induce thrombus/embolus, especially cerebral embolus. The incidence of left atrial thrombosis ( LAT) could reach 25% - 30%(1) , the incidence of embol-
文摘Objective To observe the preventive effect of continuous irrigation with sodium hyaluronate injection from peridural adhesionaminectomy.Methods Larninectomies were performed in L1,L4,L7 of 25 New Zealand rabbits respectively with 3
文摘Objective:To assess the efficacy of chlorophyl lderivative（CPD4）-Photodynamic therapy（PDT）in preventing postoperative recurrence of the in filtrativecancer of the urinary bladder-Methods:32 patients were treated with CPD4-PDT postoperationally to prevent therecurrence of can cerall of which being followedup.Results:There currenc erate was42.1%inT2 tumors and 69.2%inT3 tumors（P＜0.05）,and the survival period without tumor has been 19.8±14.8months in T2 tumors,and 22.67±19.72months in T3 tumors（P＞0.05）.There was verysignificant difference inrecurrent rate between grade I and gradeⅡ、Ⅲpatients（0%and66.7%,P<0.001）.ConcIusion:CPD4-PDT is a safe and effectiv emeasureto prevent the recurrence in infiltrative bladder cancer after operation.
文摘Objective: To study the inhibitory effect of Radix Salviae Miltiorrhizae (RSM) on adhesive and invasive ability of SMMC 7721 liver cancer cells, and on the metastasis and recurrence on post hepatectomy liver cancer in nude mice. Methods: Effect of RSM on SMMC 7721 cell membrane intercellular adhesive molecule 1 (ICAM 1) expression was observed by immunofluorescence flow cytometry; effect on invasive ability and of SMMC 7721 cell and the detachment of which attached to fibronectin (FN) by cell migration experiment; effect on adhesion of SMMC 7721 cell with FN by MTT method and effect on adhesion between 7721 7721, 7721 lymphocyte and 7721 endothelial cell by cell adhesion experiment. LCI D20 human liver cancer metastasis model, after hepatectomy, was used to observe the effect of RSM on recurrence and metastasis of liver carcinoma in nude mice. Results: ICAM 1 expression in SMMC 7721 cells incubated with RSM was significantly lower than that in cells did not treated with RSM. RSM could inhibit the invasive ability of SMMC 7721 cell and made the cells already attached to FN exfoliated. It could also inhibit the adhesion of 7721 7721, 7721 lymphocyte and 7721 endothelial cell. And RSM showed preventive and therapeutic effect on intrahepatic and remote metastasis/recurrence of early and late human post hepatectomy liver cancer in nude mice. Conclusion: RSM could inhibit the invasion and adhesion of SMMC 7721 cell and could also prevent and inhibit metastasis and recurrence of human liver cancer after hepatectomy in nude mice.
