The brain is a highly complex system. Under-standing the behavior and dynamics of billions of interconnected neurons from the brain signal requires knowledge of several signal- process-ing techniques, from the linear ...The brain is a highly complex system. Under-standing the behavior and dynamics of billions of interconnected neurons from the brain signal requires knowledge of several signal- process-ing techniques, from the linear and non-linear domains. The analysis of EEG signals plays an important role in a wide range of applications, such as psychotropic drug research, sleep studies, seizure detection and hypnosis proc-essing. In this paper we accomplish to analyze and explore the nature of hypnosis in Right, Left, Back and Frontal hemisphere in 3 groups of hypnotizable subjects by means of Fuzzy Simi-larity Index method.展开更多
目的 探索低频重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)作用于不同靶区治疗强迫症(obsessive compulsive disorder,OCD)的疗效和预测因素.方法 将93例OCD患者随机分成三组,药物组服用舍曲林治疗,SMA组服用...目的 探索低频重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)作用于不同靶区治疗强迫症(obsessive compulsive disorder,OCD)的疗效和预测因素.方法 将93例OCD患者随机分成三组,药物组服用舍曲林治疗,SMA组服用舍曲林+1Hz,rTMS作用于辅助运动区(supplementary motor area,SMA)、DLPFC组服用舍曲林+1Hz,rTMS作用于右额叶背外侧区(dorsolateral region of the right frontal lobe,right,DLPFC),共,20,次(4,周).治疗前后通过耶鲁-布朗强迫量表、汉密尔顿焦虑量表、汉密尔顿抑郁量表、总体功能评定量表评定疗效和功能,并对相关临床因素进行预测因素分析.结果 治疗后,与药物组相比,SMA组和DLPFC组的有效率、强迫行为和汉密尔顿焦虑量表评分差异均有统计学意义(P<0.05);治疗前耶鲁-布朗强迫量表评分较高可能与rTMS治疗有效呈负相关.结论 低频rTMS作用于SMA和右DLPFC对OCD均有疗效,但无明显差异;治疗前耶鲁-布朗强迫量表评分较高可能是rTMS治疗OCD疗效不佳的预测因素.展开更多
Background Children with nonverbal learning disabilities (NLD) usually manifest defective attention function This study sought to investigate the neuropsychological characteristics of selective attention, such as atte...Background Children with nonverbal learning disabilities (NLD) usually manifest defective attention function This study sought to investigate the neuropsychological characteristics of selective attention, such as attention control, working memory, and attention persistence of the frontal lobe in children with NLD Methods Using the auditory detection test (ADT), Wisconsin card sorting test (WCST), and C WISC, 27 children with NLD and 33 normal children in the control group were tested, and the results of C WISC subtests were analyzed with factor analysis Results Compared with the control group, the correct response rate in the auditory detection test in the NLD group was much lower ( P <0 01), and the number of incorrect responses was much higher ( P <0 01); NLD children also scored lower in WCST categories achieved (CA) and perseverative errors (PE) ( P <0 05) Factor analysis showed that perceptual organization (PO) related to visual space and freedom from distractibility (FD) relating to attention persistence in the NLD group were obviously lower than in the control group ( P <0 01) Conclusions Children with NLD have attention control disorder and working memory disorder mainly in the frontal lobe We believe that the disorder is particularly prominent in the right frontal lobe展开更多
文摘The brain is a highly complex system. Under-standing the behavior and dynamics of billions of interconnected neurons from the brain signal requires knowledge of several signal- process-ing techniques, from the linear and non-linear domains. The analysis of EEG signals plays an important role in a wide range of applications, such as psychotropic drug research, sleep studies, seizure detection and hypnosis proc-essing. In this paper we accomplish to analyze and explore the nature of hypnosis in Right, Left, Back and Frontal hemisphere in 3 groups of hypnotizable subjects by means of Fuzzy Simi-larity Index method.
文摘目的 探索低频重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)作用于不同靶区治疗强迫症(obsessive compulsive disorder,OCD)的疗效和预测因素.方法 将93例OCD患者随机分成三组,药物组服用舍曲林治疗,SMA组服用舍曲林+1Hz,rTMS作用于辅助运动区(supplementary motor area,SMA)、DLPFC组服用舍曲林+1Hz,rTMS作用于右额叶背外侧区(dorsolateral region of the right frontal lobe,right,DLPFC),共,20,次(4,周).治疗前后通过耶鲁-布朗强迫量表、汉密尔顿焦虑量表、汉密尔顿抑郁量表、总体功能评定量表评定疗效和功能,并对相关临床因素进行预测因素分析.结果 治疗后,与药物组相比,SMA组和DLPFC组的有效率、强迫行为和汉密尔顿焦虑量表评分差异均有统计学意义(P<0.05);治疗前耶鲁-布朗强迫量表评分较高可能与rTMS治疗有效呈负相关.结论 低频rTMS作用于SMA和右DLPFC对OCD均有疗效,但无明显差异;治疗前耶鲁-布朗强迫量表评分较高可能是rTMS治疗OCD疗效不佳的预测因素.
文摘Background Children with nonverbal learning disabilities (NLD) usually manifest defective attention function This study sought to investigate the neuropsychological characteristics of selective attention, such as attention control, working memory, and attention persistence of the frontal lobe in children with NLD Methods Using the auditory detection test (ADT), Wisconsin card sorting test (WCST), and C WISC, 27 children with NLD and 33 normal children in the control group were tested, and the results of C WISC subtests were analyzed with factor analysis Results Compared with the control group, the correct response rate in the auditory detection test in the NLD group was much lower ( P <0 01), and the number of incorrect responses was much higher ( P <0 01); NLD children also scored lower in WCST categories achieved (CA) and perseverative errors (PE) ( P <0 05) Factor analysis showed that perceptual organization (PO) related to visual space and freedom from distractibility (FD) relating to attention persistence in the NLD group were obviously lower than in the control group ( P <0 01) Conclusions Children with NLD have attention control disorder and working memory disorder mainly in the frontal lobe We believe that the disorder is particularly prominent in the right frontal lobe
