WEIGHTED PSEUDO ALMOST-PERIODIC SOLUTIONS OF SHUNTING INHIBITORY CELLULAR NEURAL NETWORKS WITH MIXED DELAYS

In this paper, we prove the existence and the global exponential stability of the unique weighted pseudo almost-periodic solution of shunting inhibitory cellular neural networks with mixed time-varying delays comprising different discrete and distributed time delays. Some sufficient conditions are given for the existence and the global exponential stability of the weighted pseudo almost-periodic solution by employing fixed point theorem and differential inequality techniques. The results of this paper complement the previously known ones. Finally, an illustrative example is given to demonstrate the effectiveness of our results.

Weighted Pseudo Almost Periodic Solutions for a Class of Hematopoiesis Model with Time-Varying Delay

In this paper, firstly, a notion of a class of generalized weighted pseudo al- most periodic function is introduced, then we investigate some basic and essential properties of the space that consists of these functions. Finally, we study the exis- tence of weighted pseudo almost periodic solutions to hematopoiesis model with time- varying delay.

INFLUENCE OF MOLECULAR WEIGHT AND PERIODATE-MODIFICATION OF β-D-GLUCANS FROM PORIA COCOS SCLEROTIUM ON ANTITUMOR ACTIVITIES

In this work, influence of molecular weight and periodate modification ofβ-D-glucans isolated from Poria cocos sclerotium on the antitumor activities against Sar-coma 180 and Ehrlich ascites carcinoma (EAC) tumor was studied. The results show thattwo glucans PC3 (linear β-(1→3)-D-glucan) and PC4 [β-(1→3)-D-glucan with a fewof branches and glucuronic acid] are devoid of antitumor activity. However, when theglucans were modified by periodate oxidation, borohydride reduction and mild hydrolysisor partially hydrolysis, the derivatives have obvious antitumor activities. The decreasein molecular weight of glucans after periodate modification hardly affects their antitumoractions, but on the other hand, the decrease of molecular weight without periodate modi-fication could lead to an enhancement of the antitumor activities. Moreover, the glucansand these derivatives have much higher enhancement ratios of body weight of mice thanthat of 5-Fluorouracil (5-Fu), suggesting that they are less toxic than 5-Fu.

Feeding Behavior, Body Weight and Growth Rate during Post-Deprivation Period in Rats

Deprivation is an environmental experience that organisms are continually exposed to. However, few studies analyze deprivation effects on the consumption pattern during the post-deprivation period systematically. The aim of this study was to evaluate the deprivation effect on feeding pattern, growth rate and body weight during post-deprivation. Sixteen albino rats (3 months old at the beginning of the experiment) were exposed to 72-hour total food deprivation every 15 days. Food and water were freely available during non-deprivation periods. Rats completed three cycles comprised by a free access period followed by food deprivation. Once deprivation was removed, food and water consumption increased and then decreased, while body weight was recovered. Growth rate increased after every deprivation period and reached similar levels to those presented by the control group. Depriving rats from one commodity (i.e., food) cause them to restrain their consumption of the other freely available commodity (i.e., water). Results confirm that food deprivation modifies growth rate, water and food consumption. Additionally, during post-deprivation period, differences between males and females were not registered.

GAUSS PERIODS AND CYCLIC CODES FROM CYCLOTOMIC SEQUENCES OF SMALL ORDERS

Let p =ef +1 be an odd prime with positive integers e and f. In this paper, we calculate the values of Gauss periods of order e =3, 4, 6 over a finite field GF(q), where q is a prime with q≠p. As applications, several cyclotomic sequences of order e =3, 4, 6 are employed to construct a number of classes of cyclic codes over GF(q) with prime length. Under certain conditions, the linear complexity and reciprocal minimal polynomials of cyclotomic sequences are calculated, and the lower bounds on the minimum distances of these cyclic codes are obtained.

结构瞬变影响下采场煤岩静态力学响应的阶变规律

为了明确采场煤岩力学响应的演变规律,以宽沟煤矿W1143长壁综采工作面为工程背景,采用物理相似模拟实验和数值计算相结合的方法,在明确来压前、后覆岩空间结构瞬变特征的基础之上,建立了一种实现坚硬岩层瞬时破断的数值模拟前处理方法,研究了结构瞬变影响下采场煤岩静态力学响应的阶变规律。结果表明:覆岩空间结构是由破裂面以外、采动影响范围以内不同岩性的岩层所组成的空间岩体结构,是其影响范围内的采场煤岩产生不同力学响应的内因。来压期间,由于坚硬岩层的破断具有瞬时性,导致覆岩空间结构发生瞬变,受此影响,采场煤岩的静态力学响应发生阶变,其本质上为一动力学过程。覆岩空间结构瞬变造成采场煤岩的应力场与位移场产生阶变,阶变集中于瞬变区域附近,距离瞬变区域越远,其阶变量越小。

Expression Specificity of Hepatic IGF-1mRNA and Its Correlation with Body Weight During Early Development of Ducks

Gaoyou and Jinding ducks with different growth rates were selected to conduct the test, and a comparative study was carried out on the expression pattern of liver insulin-like growth factor 1 （IGF-1） mRNA and its correlation with body weight in the early embryonic stage and hatching stage. The expression pattern of hepatic IGF-lmRNA of ducks at embryonic ages of 13, 17, 21,25, 27 and 0 -7 days after hatching were monitored by real-time fluorescent quantitative PCR. The results showed that expression of duck hepatic 1GF-1 mRNA could be detected at the embryonic age of 13. Body weight and hepatic IGF-1 mRNA expression of ducks both showed an increasing trend during the early development. The expression of hepatic IGF-1 mRNA of Gaoyou ducks at embryonic ages of 13, 21 and on the 7^th day after hatching was extremely significantly higher than that of Jinding ducks （P 〈 0.01 ）, which was consistent with the changes of daily weight gain and absolute growth rate. The changes of daily weight gain and hepatic IGF-I mRNA expression both showed extremely significant specificity of the breeds and time during the entire observation （P 〈 0.01）, and which was extremely significantly affected by the interaction of the breeds and time （P 〈 0.01）. The analysis on breeds and gender manifested that the change of body weight was consistent with that of hepatic IGF-I mRNA expression, which showed an extremely significant positive correlation （P 〈 0.01 ）. The results indicated that hepatic IGF-1 mRNA expression played an important role during the early development of ducks.

榆神矿区多层厚硬顶板强矿压显现及覆岩破断运动规律研究

针对榆神矿区多层厚硬顶板条件下工作面强矿压和邻空侧巷道变形严重问题,综合采用理论分析、数值计算和微震监测方法,分析了多关键层结构下顶板覆岩破断和邻空侧巷道围岩应力特征。研究结果表明:多层厚硬岩层条件下,顶板破断垂向位移和能量均呈现明显的“低、中、高”分区特征,中高位岩层破断明显滞后于低位岩层,这构成了工作面“大、小周期”的重要结构基础;本工作面开采时,相邻采空区破碎顶板大能量微震事件增多、破断强度较高,并可对邻空回风巷围岩形成强二次采动影响,这是邻空侧回风巷高应力、强变形的主要诱因。同时,高低位多关键层组合破断可导致“大周期”来压发生强度和风险上升,对关键层顶板破断运动规律进行控制是降低“大周期”强度和频率的有效途径之一。

衡重参数对超空泡航行器振荡特性的影响

为研究衡重参数对超空泡航行器振荡特性的影响规律,结合流体体积多相流模型、Realizable k-ε湍流模型、Schnerr-Sauer空化模型和刚体运动方程组,建立超空化流场和刚体运动相耦合的仿真模型,并与试验结果对比,验证仿真模型的合理性。通过仿真计算研究超空泡航行器的自由运动特性,定量总结质量和质心位置的改变对超空泡航行器振荡特性的影响规律。研究结果表明:所建模型仿真结果与试验结果变化规律一致,俯仰角和偏航角相位差1/4个周期,振荡周期约为0.0795 s,偏差不超过3.38%,仿真模型可靠;超空泡航行器的自由运动表现出类圆锥动态振荡特性;随航行器质量的减小,姿态角的振荡幅度基本不变,弹道的振荡周期逐渐减小,质量减小33.33%,周期减小13.26%;随着航行器质心位置的前移,姿态角的振荡幅度逐渐增大,弹道的振荡周期逐渐减小,质心前移25%,周期减少14.29%。

阴阳调理灸联合自我管理在更年期肥胖患者中的应用效果

目的探究更年期肥胖患者应用阴阳调理灸联合自我管理的干预效果,评估该方法对患者体重产生的影响。方法选取2021年1月至2022年12月在湖北省中医院接受诊治的60例更年期肥胖患者为研究对象,以随机数字表法为分组方式,分为对照组和观察组,各30例。对照组接受自我管理,观察组实施阴阳调理灸联合自我管理。比较2组的体格检查指标、生活质量和体质症状评分。结果干预12周后,观察组的体格检查指标(体重、腰围、体脂和臀围)测定数值均较对照组更小(P均<0.05),且2组的体格检查指标均优于干预前(P均<0.05)。干预12周后,2组的体重对生活冲击量表(IWQOL)各维度评分均低于干预前(P均<0.05);对比组间IWQOL评分,均为观察组更低(P均<0.05)。干预12周后,2组患者的额头分泌油脂多等体质症状评分均较干预前降低(P均<0.05),且观察组均低于对照组(P均<0.05)。结论阴阳调理灸联合自我管理可调理更年期肥胖患者的体质,改善其体格检查指标,减轻肥胖对于患者日常生活产生的影响。

施工期分层浇筑与温度荷载对重力坝坝踵应力影响研究

【目的】坝踵应力是评价重力坝安全的关键性控制指标。重力坝设计时自重按一次施加,并未考虑施工期大坝实际浇筑过程及温度荷载,因此,【方法】以三峡重力坝工程泄2坝段为例,基于大坝设计资料和温度监测数据,对大坝混凝土的关键热学参数进行反演。在此基础上,模拟大坝施工过程、材料性能变化过程、气温变化过程、纵缝接缝灌浆过程、通水冷却过程以及表面保温措施,进行大坝施工期全过程工作性态仿真分析,研究施工期分层浇筑与温度荷载对大坝应力尤其坝踵应力的影响。【结果】结果显示:仿真计算得到的监测点的温度变化规律与实测值吻合较好;分层浇筑模拟时自重产生的坝踵竖向压应力为7.32 MPa,自重一次施加产生的坝踵竖向压应力为7.70 MPa;施工期温度荷载引起坝踵观测部位的竖向压应力增量最大值为1.1 MPa。【结论】结果表明:自重荷载的施加方式对重力坝坝踵应力影响较小,分层浇筑自重荷载引起的坝踵竖向压应力略小于自重荷载一次施加的情况;纵缝接缝灌浆后坝体温度回升导致中块挤压上块,进而引起坝踵部位产生较大竖向压应力,这可部分解释目前重力坝实测坝踵应力多为较大压应力的原因。

胎儿体质量估计对初产妇巨大儿分娩方式及围产结局的临床观察

目的观察胎儿体质量估计对初产妇巨大儿的分娩方式和围产结局的影响。方法选取2022年1月至2023年12月北京市海淀区妇幼保健院分娩的足月单胎初产妇206例,根据估计体质量分为甲组(估计胎儿体质量<4000 g,118例)和乙组(估计胎儿体质量≥4000 g,88例)。比较两组产妇及新生儿的分娩方式和分娩结局等。结果206例初产妇年龄21~39岁,平均(30.6±3.4)岁。与乙组相比,甲组阴道分娩比例较高(61.9%比40.9%)、剖宫产比例较低(32.2%比56.8%),两组分娩方式的差异有统计学意义(P<0.05)。甲组试产率明显高于乙组(90.7%比59.1%),差异有统计学意义(P<0.05)。甲组产后出血量(容积法)和校正产后出血量均高于乙组[350(300,500)ml比300(300,380)ml,440(230,720)ml比360(160,560)ml],差异有统计学意义(P<0.05)。两组胎儿窘迫、肩难产、新生儿窒息比例的差异无统计学意义(P>0.05)。结论低估胎儿体质量可增加初产妇巨大儿试产率及阴道分娩率,也增加了产后出血量,但并未增加胎儿窘迫、肩难产、新生儿窒息等分娩并发症。建议胎儿估计体质量<4500 g且有阴道分娩意愿的产妇,应该在充分告知的情况下,增加试产机会。

浅埋低采高综采工作面安全高效回采技术研究

补连塔煤矿22501综采工作面宽度300 m,推进长度562.3 m,回采面积16.8万m2。煤厚1.5~1.8 m,煤层平均厚度1.6 m,倾角为1°~3°,地层总的趋势是以极缓的坡度向北西倾斜的单斜构造,倾角1°~3°,断层不发育,后生裂隙发育。根据四壁顺槽揭露情况,工作面无断层、冲刷等构造。对工作面初次来压及周期来压,特殊地质条件下来压情况进行了详细介绍,对类似综采工作面的回采具有指导意义。

采动覆岩裂隙发育及周期性瓦斯涌出规律研究

为获得采场覆岩裂隙发育与瓦斯涌出变化之间关系,基于淮南矿区某矿220112工作面瓦斯地质概况,综合数值模拟、理论分析及工程实践等方法,对采场应力分布、覆岩裂隙发育及瓦斯涌出周期规律进行了研究。结果表明,工作面覆岩裂隙带发育区位于顶板上方17.2~40 m内,布置在该范围的顶板大直径定向钻孔抽采效果较好,验证了理论计算及模拟结果的准确性;瓦斯涌出呈现周期性变化,2~3次顶板周期来压后工作面出现一次较大的瓦斯涌出现象,是正常回采期间瓦斯涌出量的1.5倍左右;根据工作面瓦斯涌出周期性规律,补充实施顶板走向抽采钻孔后,工作面回采期间瓦斯涌出总体平稳。

蒙陕接壤区典型煤层开采顶板周期性变形破坏及涌水响应特征

【目的】煤矿开采扰动破坏覆岩含/隔水层结构,造成集中涌水,影响矿井安全生产。【方法】以面临典型顶板砂岩水影响的蒙陕接壤区主采煤层3-1煤开采涌水过程为研究对象,采用物理相似材料模拟、数值仿真模拟、现场原位监测3种方法,并通过周边地质和开采条件相似矿井实测数据对比,分析3-1煤典型工作面开采煤体支承压力周期性演变规律、采空区覆岩垂直位移演变规律,定量获取实验室尺度顶板周期来压瞬间微震能量事件变化特征,综合确定顶板导水裂隙带随采发育特征,以及顶板涌水随覆岩周期来压变化趋势。【结果和结论】结果表明:工作面开采覆岩初次来压步距约40 m,周期性来压步距12~28 m,覆岩破断瞬间围岩周期性来压呈现“先增后稳定”的趋势,在推进至第5次周期来压(推进距离约140 m)时,超前支承压力达到最大,覆岩周期性来压、破断瞬间垂直位移峰值随采呈现“之”字型变化特征,同样,位移监测数据、微震事件总能量、事件频次等综合指标指示,在第5次周期来压瞬间,覆岩垂直位移变幅达到最大值,塑性区发育高度基本稳定;导水裂隙带发育最大高度在120 m左右,将直接沟通顶板直罗组砂岩含水层,地下水随采涌入过程呈现两种波动变化趋势,工作面全局尺度上呈现长周期“阶梯式”增长趋势,“阶梯式”增长周期约800 m,局部尺度呈现短周期“振荡”变化趋势,振荡周期16~48 m,并表现出与覆岩来压周期之间的较强关联性。研究结果为工作面涌水量预测以及防排水系统布设提供参考。

坚硬顶板水力压裂弱化技术应用

为有效改善坚硬顶板工作面来压强度,本文以寺河二号井煤矿1309工作面地质条件为基础,采用现场试验与监测等方法,对坚硬顶板水力压裂技术进行了应用,设计了切眼及顺槽巷道水力压裂钻孔参数,并在现场进行了实践。根据水力压裂后巷道顶板窥视结果与矿压显现结果,采用水力压裂技术后顶板压裂效果较好,初次来压步距减小21%,周期来压步距减小17%,水力压裂技术能实现弱化顶板的效果。

妊娠期体质量干预方式的研究进展

对妊娠期体质量增长推荐标准、相关理论及干预方法进行综述。明确国内开展妊娠期体质量干预存在的问题,并提出需实施生活方式干预、心理行为干预、以助产士为主导及基于互联网和信息化平台的多学科干预策略,旨在降低妊娠期超重、肥胖及妊娠期体质量增长异常对母婴的危害,保障母婴安全。

荷斯坦牛肌肉组织中与妊娠末期、泌乳期及繁殖力相关的基因共表达网络构建

【目的】筛选荷斯坦牛肌肉组织中与妊娠末期、泌乳期及繁殖力相关的关键目标基因,为进一步开展基因功能研究提供理论依据。【方法】选择GEO数据库中有关荷斯坦牛在妊娠末期、泌乳早期和泌乳中期肌肉基因表达及生育能力的数据集GSE62159,采用加权基因共表达网络分析(Weighted gene co-expression network analysis,WGCNA)方法进行基因共表达分析,将获得的模块与妊娠末期、泌乳中期及繁殖力性状相关联,选择各模块中连接度处于前30的基因作为枢纽基因(Hub基因),使用String网站对模块进行蛋白互作(Protein-protein interaction,PPI)网络分析,选择PPI网络中节点连接度值排名前30的基因作为核心基因,与Hub基因交集得到在肌肉中与不同生理时期及繁殖力相关的关键目标基因。【结果】研究共分析得到13个模块,其中Green、Blue两个模块分别与妊娠末期、泌乳中期相关,Magenta模块与繁殖力相关。对各目标模块内基因进行功能富集分析,富集结果显示肌肉组织中与妊娠末期相关的基因功能主要有物质代谢、能量代谢、蛋白质合成与分泌、机体对氧化应激的反应及神经退行性变等;与泌乳中期相关的基因功能有干细胞群维持、蛋白质合成与分泌、抗原加工与呈递及多种疾病发生等;与繁殖力相关的基因功能有血管形成、子宫内胚胎发育与肌动蛋白丝结合等。筛选到荷斯坦牛肌肉中与妊娠末期相关的关键基因有3个、与泌乳中期相关的关键基因有1个、与繁殖力相关的关键基因有8个。【结论】鉴定到荷斯坦牛肌肉组织中与妊娠末期相关的基因为EIF5A、ACO2和EEF1G,与泌乳中期相关的基因为EIF4A2,与繁殖力相关的基因为ITGB1、MYH9、TLN1、CAV1、COL4A1、COL4A2、FLNA和HSPG2。

基于POI-ConvLSTM模型的周期来压预测研究

针对综采工作面周期来压预测的技术难题,研究了理论分析、数据采集与预处理、模型评估与优化等方法,提出了具有时空关联分析与POI(Point of Intersesting)数据的ConvLSTM模型,利用多源数据融合得到周期来压预测的最优解,实现工作面环境状态的实时感知和预测。试验结果表明:基于POI-ConvLSTM的工作面周期来压预测模型,均方误差为0.159,R 2评价指标为0.999,相比于Seq2Seq和ConvLSTM模型的均方误差分别降低了68.07%和4.22%。可见,融合了多元数据POI-ConvLSTM模型的预测精度更高,普适性更强,能够准确地提前预测周期来压问题。

综放工作面周期来压判定与冲击危险处置

冲击地压煤层综放开采过程中,顶板会发生周期来压,释放大能量震动,诱发冲击显现,因此准确掌握工作面周期来压规律对冲击地压防治是极其重要的。针对周期来压单一方法分析误差较大的缺陷,通过对工作面回采过程中微震监测指标“震动频次”“震源能量”、瓦斯涌出量变化以及工作面支架压力分布云图分析,提出一种“微震-支架压力-瓦斯涌出量”综合判定方法。实践表明,该方法能够准确预测甘肃某矿250107-1工作面来压周期,并提出了“断顶-松动”爆破相结合的顶板弱化方法,可以有效降低冲击地压的危害。