Previous studies of integrin αvβ3 have focused on ischemic brain damage, although the role of integrin αvβ3 in ischemic preconditioning (IP) has rarely been reported. The present study analyzed the effects of IP...Previous studies of integrin αvβ3 have focused on ischemic brain damage, although the role of integrin αvβ3 in ischemic preconditioning (IP) has rarely been reported. The present study analyzed the effects of IP on integrin αvβ3 mRNA expression following cerebral ischemia through the use of hematoxylin-eosin staining and real-time quantitative polymerase chain reaction techniques. Integrin avid3 mRNA expression in the ischemia group peaked at 24 hours after ischemia-reperfusion. In the IP + ischemia group, integrin αvβ3 mRNA expression increased after 24 hours, but remained significantly less than the ischemia group, and expression continued to increase until 7 days after ischemiaJreperfusion. These results demonstrate that IP effectively attenuated upregulation of integrin αvβ3 mRNA expression at 24 hours after ischemia.展开更多
为解决交通道路小目标检测难度大、精度低,容易出现错检漏检的问题,提出一种基于YOLO v5(you only look once v5)算法的多尺度特征融合目标检测改进算法。首先,增加小目标检测头用于适应小目标尺寸,缓解漏检情况。然后,引入可变形卷积网...为解决交通道路小目标检测难度大、精度低,容易出现错检漏检的问题,提出一种基于YOLO v5(you only look once v5)算法的多尺度特征融合目标检测改进算法。首先,增加小目标检测头用于适应小目标尺寸,缓解漏检情况。然后,引入可变形卷积网络v2(deformable convolutional networks V2,DCN V2)提高模型对运动中小目标的学习能力;同时,增加上下文增强模块,提升对远距离小目标的识别能力。最后,在替换损失函数、提高边界框定位精度的同时,使用空间金字塔池化和上下文空间金字塔卷积分组模块,提高网络的感受野和特征表达能力。实验结果表明,所提算法在KITTI数据集小目标类别上平均识别精度达到了95.2%,相较于原始YOLO v5,算法总体平均识别精度提升了2.7%,对小目标的检测效果更佳,平均识别精度提升了3.1%,证明所提算法在道路小目标检测方面的有效性。展开更多
基金the National Natural Science Foundation of China,No. 30870849,81071068the Science and Technology Planning Project of Guangdong Province,No. 2009B030801101
文摘Previous studies of integrin αvβ3 have focused on ischemic brain damage, although the role of integrin αvβ3 in ischemic preconditioning (IP) has rarely been reported. The present study analyzed the effects of IP on integrin αvβ3 mRNA expression following cerebral ischemia through the use of hematoxylin-eosin staining and real-time quantitative polymerase chain reaction techniques. Integrin avid3 mRNA expression in the ischemia group peaked at 24 hours after ischemia-reperfusion. In the IP + ischemia group, integrin αvβ3 mRNA expression increased after 24 hours, but remained significantly less than the ischemia group, and expression continued to increase until 7 days after ischemiaJreperfusion. These results demonstrate that IP effectively attenuated upregulation of integrin αvβ3 mRNA expression at 24 hours after ischemia.