The fluorination reaction involving a β-ketosulfones by Selectfluor^TM was efficiently promoted by the ionic liquid, [Hbim]BF4 （IL） as a reaction medium with methanol as co-solvent at room temperature under ultraso...The fluorination reaction involving a β-ketosulfones by Selectfluor^TM was efficiently promoted by the ionic liquid, [Hbim]BF4 （IL） as a reaction medium with methanol as co-solvent at room temperature under ultrasonic irradiation to afford the corresponding mono and difluoro-β-ketosulfones in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under room temperature without the requirement of any added catalyst under ultrasonic irradiation.展开更多
An efficient and broadly applicable protocol for the aerobic coupling of styrenes with sulfonylhydrazides has been developed that affords P-ketosulfones bearing various functional groups in moderate to excellent yield...An efficient and broadly applicable protocol for the aerobic coupling of styrenes with sulfonylhydrazides has been developed that affords P-ketosulfones bearing various functional groups in moderate to excellent yields.The preliminary experimental results support the involvement of active benzyl radical species,and a radical pathway was therefore proposed for the reaction.展开更多
文摘The fluorination reaction involving a β-ketosulfones by Selectfluor^TM was efficiently promoted by the ionic liquid, [Hbim]BF4 （IL） as a reaction medium with methanol as co-solvent at room temperature under ultrasonic irradiation to afford the corresponding mono and difluoro-β-ketosulfones in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under room temperature without the requirement of any added catalyst under ultrasonic irradiation.
基金supported by the National Natural Science Foundation of China(U1504210)the China Postdoctoral Science Foundation funded project(2015M572110)Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis(130028651)
文摘An efficient and broadly applicable protocol for the aerobic coupling of styrenes with sulfonylhydrazides has been developed that affords P-ketosulfones bearing various functional groups in moderate to excellent yields.The preliminary experimental results support the involvement of active benzyl radical species,and a radical pathway was therefore proposed for the reaction.
基金Project supported by the Natural Science Foundation of Jiangsu Province(No.BK20150652)the National Natural Science Foundation of China(No.21502096)+1 种基金the Fundamental Research Funds for the Central Universities(No.KJQN201629)"333 High Level Talent Project"of Jiangsu Province~~
