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Fast neutron radiation inactivation of Bacillus subtilis:Absorbed dose determination 被引量:3
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作者 SONG Lingli ZHENG Chun AI Zihui LI Junjie DAI Shaofeng 《Nuclear Science and Techniques》 SCIE CAS CSCD 2011年第3期156-159,共4页
In this paper,fast neutron inactivation effects of Bacillus subtilis were investigated with fission fast neutrons from CFBR-Ⅱreactor of INPC(Institute of Nuclear Physics and Chemistry)and mono-energetic neutrons from... In this paper,fast neutron inactivation effects of Bacillus subtilis were investigated with fission fast neutrons from CFBR-Ⅱreactor of INPC(Institute of Nuclear Physics and Chemistry)and mono-energetic neutrons from the Van de Graaff accelerator at Peking University.The method for determining the absorbed dose in the Bacillus subtilis suspension contained in test tubes is introduced.The absorbed dose,on account of its dependence on the volume and the form of confined state,was determined by combined experiments and Monte Carlo method.Using the calculation results of absorbed dose,the fast neutron inactivation effects on Bacillus subtilis were studied.The survival rates and absorbed dose curve was constructed. 展开更多
关键词 枯草芽孢杆菌 吸收剂量 中子辐射 测定 失活 蒙特卡罗方法 灭活效果 化学研究所
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Multiphase Interfacial Regulation Based on Hierarchical Porous Molybdenum Selenide to Build Anticorrosive and Multiband Tailorable Absorbers 被引量:1
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作者 Tianbao Zhao Zirui Jia +3 位作者 Jinkun Liu Yan Zhang Guanglei Wu Pengfei Yin 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第1期85-105,共21页
Electromagnetic wave(EMW)absorbing materials have an irreplaceable position in the field of military stealth as well as in the field of electromagnetic pollution control.And in order to cope with the complex electroma... Electromagnetic wave(EMW)absorbing materials have an irreplaceable position in the field of military stealth as well as in the field of electromagnetic pollution control.And in order to cope with the complex electromagnetic environment,the design of multifunctional and multiband high efficiency EMW absorbers remains a tremendous challenge.In this work,we designed a three-dimensional porous structure via the salt melt synthesis strategy to optimize the impedance matching of the absorber.Also,through interfacial engineering,a molybdenum carbide transition layer was introduced between the molybdenum selenide nanoparticles and the three-dimensional porous carbon matrix to improve the absorption behavior of the absorber.The analysis indicates that the number and components of the heterogeneous interfaces have a significant impact on the EMW absorption performance of the absorber due to mechanisms such as interfacial polarization and conduction loss introduced by interfacial engineering.Wherein,the prepared MoSe_(2)/MoC/PNC composites showed excellent EMW absorption performance in C,X,and Ku bands,especially exhibiting a reflection loss of−59.09 dB and an effective absorption bandwidth of 6.96 GHz at 1.9 mm.The coordination between structure and components endows the absorber with strong absorption,broad bandwidth,thin thickness,and multi-frequency absorption characteristics.Remarkably,it can effectively reinforce the marine anticorrosion property of the epoxy resin coating on Q235 steel substrate.This study contributes to a deeper understanding of the relationship between interfacial engineering and the performance of EMW absorbers,and provides a reference for the design of multifunctional,multiband EMW absorption materials. 展开更多
关键词 Interfacial engineering ANTICORROSION MULTIBAND Electromagnetic wave absorber
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Comparison of Absorbed Dose to Medium and Absorbed Dose to Water for Spine IMRT Plans Using a Commercial Monte Carlo Treatment Planning System 被引量:1
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作者 Muhammad Nauman Usmani Norihisa Masai +5 位作者 Ryoong-Jin Oh Hiroya Shiomi Daisaku Tatsumi Hideharu Miura Toshihiko Inoue Masahiko Koizumi 《International Journal of Medical Physics, Clinical Engineering and Radiation Oncology》 2014年第1期60-66,共7页
Dose in radiation therapy has been reported as the water-equivalent dose using conventional dose calculation algorithms. The Monte Carlo (MC) algorithm employs characterization of human tissues by elemental compositio... Dose in radiation therapy has been reported as the water-equivalent dose using conventional dose calculation algorithms. The Monte Carlo (MC) algorithm employs characterization of human tissues by elemental composition and mass density. It enables more accurate dose calculation for radiation therapy treatment planning and typically reports absorbed dose to medium. Whether one should use dose to medium or tissue (Dm) in place of dose to water (Dw) for MC treatment planning remains the subject of debate. The aim of the current study is to evaluate the differences between dose-volume indices for Dm and Dw MC-calculated IMRT plans. Thirty-seven spine patients were selected for this study. The IMRT optimization and MC calculations were performed using the iPlan RT DoseTM ver 4.1.2 (Brainlab, Munich, Germany) treatment planning system (TPS) with an X-ray Voxel Monte Carlo (XVMC) dose calculation engine. Dw and Dm results for target and critical structures were evaluated using the dose-volume-based indices. Systematic differences between dose-volume indices computed with Dw and Dm were up to 5.2%, 4.2%, and 4.5% for D2, D50 and D98 indices of the clinical target volume (CTV), respectively and up to 1% for the critical structure dose indices. Our study demonstrates that employing Dm in place of Dw in MC-calculated IMRT treatment plans introduces a significant systematic difference in target DVHs. We recommend that for diffused target structures (such as spine tumors), dose to water is a better quantity for dose prescription in photon beam treatment planning using existing MC TPS. While for critical structures, it would be reasonable to report Dm always. However in future with the availability of finer spatial resolution, Dm will be the most suitable variable for both target and critical structures’ dose prescription and reporting in MC treatment planning. 展开更多
关键词 dose to MEDIUM dose to WATER Monte Carlo IMRT
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Mechanism and Method of Testing Fracture Toughness and Impact Absorbed Energy of Ductile Metals by Spherical Indentation Tests
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作者 Jianxun Li Tairui Zhang +2 位作者 Shang Wang Jirui Cheng Weiqiang Wang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2023年第5期156-173,共18页
To address the problem of conventional approaches for mechanical property determination requiring destructive sampling, which may be unsuitable for in-service structures, the authors proposed a method for determining ... To address the problem of conventional approaches for mechanical property determination requiring destructive sampling, which may be unsuitable for in-service structures, the authors proposed a method for determining the quasi-static fracture toughness and impact absorbed energy of ductile metals from spherical indentation tests (SITs). The stress status and damage mechanism of SIT, mode I fracture, Charpy impact tests, and related tests were frst investigated through fnite element (FE) calculations and scanning electron microscopy (SEM) observations, respectively. It was found that the damage mechanism of SITs is diferent from that of mode I fractures, while mode I fractures and Charpy impact tests share the same damage mechanism. Considering the diference between SIT and mode I fractures, uniaxial tension and pure shear were introduced to correlate SIT with mode I fractures. Based on this, the widely used critical indentation energy (CIE) model for fracture toughness determination using SITs was modifed. The quasi-static fracture toughness determined from the modifed CIE model was used to evaluate the impact absorbed energy using the dynamic fracture toughness and energy for crack initiation. The efectiveness of the newly proposed method was verifed through experiments on four types of steels: Q345R, SA508-3, 18MnMoNbR, and S30408. 展开更多
关键词 Spherical indentation tests Fracture toughness CIE model Impact absorbed energy
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The Effect of the Size of Radiotherapy Photon Beams on the Absorbed Dose to an Al_2O_3 Dosimeter
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作者 陈少文 张文澜 +2 位作者 范丽仙 唐强 刘小伟 《Plasma Science and Technology》 SCIE EI CAS CSCD 2012年第6期558-562,共5页
The effect of the size of radiotherapy photon beams on the absorbed dose to an Al2O3 dosimeter was investigated using the Monte Carlo method. The EGSnrc/DOSRZnrc program code was used to simulate the absorbed dose to ... The effect of the size of radiotherapy photon beams on the absorbed dose to an Al2O3 dosimeter was investigated using the Monte Carlo method. The EGSnrc/DOSRZnrc program code was used to simulate the absorbed dose to the Al2O3 dosimeter, as well as the absorbed dose to water at the corresponding position in the absence of the dosimeter. The incident beams were 60Co γ and 6 MV with a different beam radius ranging from 0.1 cm to 2 cm. Results revealed that the absorbed dose ratio factor depends on the size of the incident photon beam. When the radius of the incident beam is smaller than that of the dosimeter, the absorbed dose ratio factor decreases as the incident beam size increases. The absorbed dose ratio factor reaches its minimum when the radius of the incident beam is almost the same as that of the dosimeter. When the radius of the incident beam is larger than that of the dosimeter, the absorbed dose ratio factor increases as the incident beam size increases. The maximum difference among these absorbed dose ratio factors can be up to 14% in 60Co γ beams and 23% in 6 MV beams. However, when the size of the incident beam is much larger than that of the dosimeter, the effect of the incident beam size on the absorbed dose ratio factor becomes quite small. The maximum discrepancy between the absorbed dose ratio factors and the average value is not more than 1%. 展开更多
关键词 Al2O3 dosimeter absorbed dose Monte Carlo radiotherapy photon beams
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Ensuring Uniformity of Measurements of Absorbed Doses of Intensive Photon and Electron Radiation in Radiation Technologies
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作者 V. V. Generalova A. A. Gromov O. I. Kovalenko 《Journal of Applied Mathematics and Physics》 2015年第8期942-946,共5页
Ensuring reliability and traceability of the unit of absorbed dose of intense photon and electron radiation, used in radiation technologies in industry, is based on the creation of a system of sample measures and meth... Ensuring reliability and traceability of the unit of absorbed dose of intense photon and electron radiation, used in radiation technologies in industry, is based on the creation of a system of sample measures and methods of transmission with minimal loss of dimensional accuracy of the unit of absorbed dose from the sample tools to working dosimeters and is a necessary basis of yield growth, of increase of labour productivity and the introduction of innovative products. The measuring capabilities of the State primary special standard of power unit of absorbed dose of intensity photon, electron and beta radiation for radiation technologies and of the standards of the absorbed dose of photon and electron radiation, used for radiation monitoring of radiation pro- cesses. 展开更多
关键词 RADIATION Technology absorbed dose Ensuring UNIFORMITY of MEASUREMENTS Certified Reference Material
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Accurate models and nutritional strategies for specific oxidative stress factors: Does the dose matter in swine production?
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作者 Changming Hong Yujian Huang +6 位作者 Shuting Cao Li Wang Xuefen Yang Shenglan Hu Kaiguo Gao Zongyong Jiang Hao Xiao 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第2期519-534,共16页
Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxid... Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxidant strategies in relation to oxidative stress-induced pig production,it remains so far largely unsuccessful to develop accurate models and nutritional strategies for specific oxidative stress factors.Here,we discuss the dose and dose intensity of the causes of oxidative stress involving physiological,environmental and dietary factors,recent research models and the antioxidant strategies to provide theoretical guidance for future oxidative stress research in swine. 展开更多
关键词 Accurate models dose Nutritional strategies Oxidative stress SWINE
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Helicobacter pylori:High dose amoxicillin does not improve primary or secondary eradication rates in an Irish cohort
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作者 Conor Costigan Aoife M O'Sullivan +10 位作者 Jim O'Connell Shreyashee Sengupta Thomas Butler Stephen Molloy Fintan John O'Hara Barbara Ryan Niall Breslin Sarah O'Donnell Anthony O'Connor Sinead Smith Deirdre McNamara 《World Journal of Clinical Cases》 SCIE 2024年第16期2773-2779,共7页
BACKGROUND Helicobacter pylori(H.pylori)eradication rates have fallen globally,likely in large part due to increasing antibiotic resistance to traditional therapy.In areas of high clarithromycin and metronidazole resi... BACKGROUND Helicobacter pylori(H.pylori)eradication rates have fallen globally,likely in large part due to increasing antibiotic resistance to traditional therapy.In areas of high clarithromycin and metronidazole resistance such as ours,Maastricht VI guidelines suggest high dose amoxicillin dual therapy(HDADT)can be considered,subject to evidence for local efficacy.In this study we assess efficacy of HDADT therapy for H.pylori eradication in an Irish cohort.AIM To assess the efficacy of HDADT therapy for H.pylori eradication in an Irish cohort as both first line,and subsequent therapy for patients diagnosed with H.pylori.METHODS All patients testing positive for H.pylori in a tertiary centre were treated prospectively with HDADT(amoxicillin 1 g tid and esomeprazole 40 mg bid×14 d)over a period of 8 months.Eradication was confirmed with Urea Breath Test at least 4 wk after cessation of therapy.A delta-over-baseline>4%was considered positive.Patient demographics and treatment outcomes were recorded,analysed and controlled for basic demographics and prior H.pylori treatment.RESULTS One hundred and ninety-eight patients were identified with H.pylori infection,10 patients were excluded due to penicillin allergy and 38 patients refused follow up testing.In all 139 were included in the analysis,55%(n=76)were female,mean age was 46.6 years.Overall,93(67%)of patients were treatment-naïve and 46(33%)had received at least one previous course of treatment.The groups were statistically similar.Self-reported compliance with HDADT was 97%,mild side-effects occurred in 7%.There were no serious adverse drug reactions.Overall the eradication rate for our cohort was 56%(78/139).Eradication rates were worse for those with previous treatment[43%(20/46)vs 62%(58/93),P=0.0458,odds ratio=2.15].Age and Gender had no effect on eradication status.CONCLUSION Overall eradication rates with HDADT were disappointing.Despite being a simple and possibly better tolerated regime,these results do not support its routine use in a high dual resistance country.Further investigation of other regimens to achieve the>90%eradication target is needed. 展开更多
关键词 Helicobacter pylori eradication Helicobacter pylori High dose amoxicillin High dose amoxicillin dual therapy Triple therapy
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Determination of Timer Error and Evaluation of Its Effect on Dose for OB6, GammaBeam X200 and X-Ray Irradiators at the Secondary Standard Dosimetry Laboratory in Nigeria
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作者 Olumide Olaife Akerele Samuel Mofolorunsho Oyeyemi +3 位作者 David Olakanmi Olaniyi Francis Adole Agada Bamidele Musbau Adeniran Latifat Ronke Owoade 《World Journal of Nuclear Science and Technology》 CAS 2024年第2期118-130,共13页
Timer error as well as its convention is very important for dose accuracy during irradiation. This paper determines the timer error of irradiators at Secondary Standard Dosimetry Laboratory (SSDL) in Nigeria. The irra... Timer error as well as its convention is very important for dose accuracy during irradiation. This paper determines the timer error of irradiators at Secondary Standard Dosimetry Laboratory (SSDL) in Nigeria. The irradiators are Cs-137 OB6 irradiator and X-ray irradiators at the Protection level SSDL;and Co-60 irradiator at the Therapy Level SSDL. PTW UNIDOS electrometer and LS01 Ionization chamber were used at the Protection Level to obtain doses for both Cs-137 OB6 and X-ray irradiators while an IBA farmer type ionization chamber and an IBA DOSE 1 electrometer were used at the Protection Level SSDL. Single/multiple exposure method and graphical method were used in the determination of the timer error for the three irradiators. The timer error obtained for Cs-137 OB6 irradiator was 0.48 ± 0.01 s, the timer error for the X-ray irradiator was 0.09 ± 0.01 s while the timer error obtained for GammaBeam X200 was 1.21 ± 0.04 s. It was observed that the timer error is not affected by source to detector distance. It was also observed that the timer error of Co-60 Gamma X200 irradiator is increasing with the age of the machine. Source to detector distance and field size do not contribute towards the timer error of the irradiators. The timer error of the Co-60 Gamma X200 irradiator (the only irradiator among the irradiators with a pneumatic system) increases with the age of the irradiator. 展开更多
关键词 Timer Error Irradiation SSDL Irradiators dose Accuracy
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Ultra-broadband microwave absorber and high-performance pressure sensor based on aramid nanofiber,polypyrrole and nickel porous aerogel
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作者 Leyi Zhang Hongyu Jin +7 位作者 Hanxin Liao Rao Zhang Bochong Wang Jianyong Xiang Congpu Mu Kun Zhai Tianyu Xue Fusheng Wen 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第8期1912-1921,共10页
Electronic devices have become ubiquitous in our daily lives,leading to a surge in the use of microwave absorbers and wearable sensor devices across various sectors.A prime example of this trend is the aramid nanofibe... Electronic devices have become ubiquitous in our daily lives,leading to a surge in the use of microwave absorbers and wearable sensor devices across various sectors.A prime example of this trend is the aramid nanofibers/polypyrrole/nickel(APN)aerogels,which serve dual roles as both microwave absorbers and pressure sensors.In this work,we focused on the preparation of aramid nanofibers/polypyrrole(AP15)aerogels,where the mass ratio of aramid nanofibers to pyrrole was 1:5.We employed the oxidative polymerization method for the preparation process.Following this,nickel was thermally evaporated onto the surface of the AP15 aerogels,resulting in the creation of an ultralight(9.35 mg·cm^(-3)).This aerogel exhibited a porous structure.The introduction of nickel into the aerogel aimed to enhance magnetic loss and adjust impedance matching,thereby improving electromagnetic wave absorption performance.The minimum reflection loss value achieved was-48.7 dB,and the maximum effective absorption bandwidth spanned 8.42 GHz with a thickness of 2.9 mm.These impressive metrics can be attributed to the three-dimensional network porous structure of the aerogel and perfect impedance matching.Moreover,the use of aramid nanofibers and a three-dimensional hole structure endowed the APN aerogels with good insulation,flame-retardant properties,and compression resilience.Even under a compression strain of 50%,the aerogel maintained its resilience over 500 cycles.The incorporation of polypyrrole and nickel particles further enhanced the conductivity of the aerogel.Consequently,the final APN aerogel sensor demonstrated high sensitivity(10.78 kPa-1)and thermal stability.In conclusion,the APN aerogels hold significant promise as ultra-broadband microwave absorbers and pressure sensors. 展开更多
关键词 porous aerogel aramid nanofibers microwave absorbers pressure sensor porous structure
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Study of relationship between motion of mechanisms in gas operated weapon and its shock absorber
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作者 Jiri Balla Roman Vitek +2 位作者 Dung Nguyen Van Zbynek Krist Hung Nguyen Van 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期42-54,共13页
The article deals with the motion of the breech block carrier and the weapon casing of an automatic weapon mounted on a flexible carriage and the base of the weapon.Earlier works,which did not consider the dynamic pro... The article deals with the motion of the breech block carrier and the weapon casing of an automatic weapon mounted on a flexible carriage and the base of the weapon.Earlier works,which did not consider the dynamic properties of the base of the weapon,did not allow to reconcile the calculated and experimental results of the weapon casing displacement when shooting from firing rests.For the analysis of the motion of individual parts,the methods of mathematical modelling and firing experiments using a high-speed camera were chosen.Calculations show the best accord with experiment when modelling the system with 4 degrees of freedom.The oscillation of the system regarding the movement of the breech block carrier and the weapon casing was investigated under changed conditions of rate of fire,the use of a muzzle brake and different types of shock absorbers.The velocities and displacements of the weapon casing and the breech block carrier at different values of the impulse of the gases to the breech block carrier were determined. 展开更多
关键词 Shock absorber Gas-operated weapon Force-impulse diagram Recoil system Breech block carrier
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A flexible ultra-broadband multi-layered absorber working at 2 GHz-40 GHz printed by resistive ink
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作者 汪涛 闫玉伦 +3 位作者 陈巩华 李迎 胡俊 毛剑波 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期329-333,共5页
A flexible extra broadband metamaterial absorber(MMA)stacked with five layers working at 2 GHz–40 GHz is investigated.Each layer is composed of polyvinyl chloride(PVC),polyimide(PI),and a frequency selective surface(... A flexible extra broadband metamaterial absorber(MMA)stacked with five layers working at 2 GHz–40 GHz is investigated.Each layer is composed of polyvinyl chloride(PVC),polyimide(PI),and a frequency selective surface(FSS),which is printed on PI using conductive ink.To investigate this absorber,both one-dimensional analogous circuit analysis and three-dimensional full-wave simulation based on a physical model are provided.Various crucial electromagnetic properties,such as absorption,effective impedance,complex permittivity and permeability,electric current distribution and magnetic field distribution at resonant peak points,are studied in detail.Analysis shows that the working frequency of this absorber covers entire S,C,X,Ku,K and Ka bands with a minimum thickness of 0.098λ_(max)(λ_(max) is the maximum wavelength in the absorption band),and the fractional bandwidth(FBW)reaches 181.1%.Moreover,the reflection coefficient is less than-10 dB at 1.998 GHz–40.056 GHz at normal incidence,and the absorptivity of the plane wave is greater than 80%when the incident angle is smaller than 50°.Furthermore,the proposed absorber is experimentally validated,and the experimental results show good agreement with the simulation results,which demonstrates the potential applicability of this absorber at 2 GHz–40 GHz. 展开更多
关键词 extra broadband physical model flexible metamaterial absorber MULTI-LAYER frequency selective surface
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Heat Transfer Enhancement of the Absorber Tube in a Parabolic Trough Solar Collector through the Insertion of Novel Cylindrical Turbulators
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作者 Yasser Jebbar Fadhil Fluiful Wisam Khudhayer 《Fluid Dynamics & Materials Processing》 EI 2024年第6期1279-1297,共19页
This study includes an experimental and numerical analysis of the performances of a parabolic trough collector(PTC)with and without cylindrical turbulators.The PTC is designed with dimensions of 2.00 m in length and 1... This study includes an experimental and numerical analysis of the performances of a parabolic trough collector(PTC)with and without cylindrical turbulators.The PTC is designed with dimensions of 2.00 m in length and 1.00 m in width.The related reflector is made of lined sheets of aluminum,and the tubes are made of stainless steel used for the absorption of heat.They have an outer diameter of 0.051 m and a wall thickness of 0.002 m.Water,used as a heat transfer fluid(HTF),flows through the absorber tube at a mass flow rate of 0.7 kg/s.The dimensions of cylindrical turbulators are 0.04 m in length and 0.047 m in diameter.Simulations are performed using the ANSYS Fluent 2020 R2 software.The PTC performance is evaluated by comparing the experimental and numerical outcomes,namely,the outlet temperature,useful heat,and thermal efficiency for a modified tube(MT)(tube with novel cylindrical turbulators)and a plain tube(PT)(tube without novel cylindrical turbulators).According to the results,the experimental outlet temperatures recorded 63.2°C and 50.5°C for the MT and PT,respectively.The heat gain reaches 1137.5 Win the MT and 685.8 Win the PT.Compared to the PT collector,the PTC exhibited a(1.64 times)higher efficiency. 展开更多
关键词 Parabolic trough collector turbulators absorber tube ANSYS thermal efficiency
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Validation of the TOPAS Monte-Carlo Code of the Off-Field Dose of a 6 MV Synergy Linac
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作者 Kodjo Joel Fabrice N’Guessan Ibrahima Sakho Bogbé D. L. H. Gogon 《Journal of Biosciences and Medicines》 2024年第7期38-54,共17页
The risk of radiation-induced second cancer and the late tissue loss due to Off-field doses in radiotherapy remain a serious concern. Monte Carlo (MC) simulation is currently one of the most accurate methods for calcu... The risk of radiation-induced second cancer and the late tissue loss due to Off-field doses in radiotherapy remain a serious concern. Monte Carlo (MC) simulation is currently one of the most accurate methods for calculating these doses. MC simulation model based on the Particle Simulation Tool (TOPAS) has been developed to simulate the off-field dose of an Elekta Synergy linear accelerator (Linac) emitting 6 MV photons. Measurements were taken in a water phantom using an ionization chamber to validate this model. The Percentage Depth Dose (PDD) at the depth of 0.0, 5.0, 10.0 and 15.0 cm from the beam axis for a 10 × 10 cm2 field size was measured and simulated. Off-field dose profiles at the depth of 1.5 (dmax), 5.0 and 10.0 cm for field sizes of 5 × 5, 10 × 10, 15 × 15, and 20 × 20 cm2 respectively were measured and simulated. Comparison of measured and simulated off-field dose values showed a good agreement. The average gamma passing rate of the PDDs and profiles curves for off-field doses were 87.5% and 98.11% respectively. The local dose difference based on the PDD curve between the measured and simulated was less than 6.0 % for all locations. For all field size considered in this study, the average difference between profile curves for off-field dose measured and simulated was 9.1%. PDDs and Profiles curves for off-field dose simulation uncertainties were less than 2.0% and 1.0% respectively. TOPAS-MC simulation model developed is a good representation of our 6 MV Linac Elekta Synergy for assessing off-field dose, which would be the primary cause of some secondary cancers. 展开更多
关键词 Radiotherapy Off-Field dose Secondary Cancer TOPAS-MC Simulation DOSIMETRY
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Life Time Attributable Cancer Risk Estimated Using Scanner Reported Dose Length Product during Chest Computed Tomography Imaging in Young Children
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作者 Mousa Bakkari Khaled Soliman +3 位作者 Abdullah Alrushoud Marwan Fahad Alosaimi Hanaa Alsheikh Abdelwahed Alhejaili 《Open Journal of Radiology》 2024年第2期74-82,共9页
This study aims to estimate the lifetime attributable cancer risk (LAR) for pediatric chest computed tomography (CT) examinations in five age groups using recently published age and region-specific conversion coeffici... This study aims to estimate the lifetime attributable cancer risk (LAR) for pediatric chest computed tomography (CT) examinations in five age groups using recently published age and region-specific conversion coefficients multiplying the widely available scanner registered dose length products (DLP) displayed on the CT console and hence calculating the Effective Dose (ED). The ED is then multiplied by the International Commission on Radiological Protection (ICRP) published risk factor for LAR. The obtained LAR values are compared with the international literature. Factors that may affect the LAR value are reported and discussed. The study included one hundred twenty five chest CT examinations for both males and females aged from less than one year to fifteen years. The patients reported data are from one single medical institution and using two CT scanners from June 2022 to December 2023. The results of this study may serve as benchmark for institutional radiation dose reference levels and risk estimation. 展开更多
关键词 Cancer Risk LAR Chest CT Pediatric Radiology Radiation dose DLP
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Preparation and Swelling Kinetic Analysis of Poly (HPMC-co-AA-co-AM) Super Absorbent Resin
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作者 马砺 WANG Xin +2 位作者 LIU Xixi WEI Gaoming GUO Ying 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第3期790-799,共10页
Super absorbent resin(SAR)is prepared by aqueous high temperature polymerization using hydroxypropyl methylcellulose(HPMC)as monomer backbone material,acrylic acid(AA)and acrylamide(AM)as the graft copolymer monomer,p... Super absorbent resin(SAR)is prepared by aqueous high temperature polymerization using hydroxypropyl methylcellulose(HPMC)as monomer backbone material,acrylic acid(AA)and acrylamide(AM)as the graft copolymer monomer,potassium persulfate(KPS)as the initiator to generate free radicals,and N,N`-methylenebisacrylamide(MBA)as cross-linking agent for cross-linking reaction.Simutaneously,the influence of individual factors on the water absorption is investigated,and these factors are mainly AA,AM,KPS,MBA,HPMC,and reaction temperature.The optimized conditions are obtained by the experiment repeating for several times.The water absorption multiplicity and salt absorption multiplicity under the conditions are 782.4 and 132.5 g/g,respectivity.Furthermore,the effects of different temperatures and salt concentrations on its water absorption,as well as the swelling kinetics of SAR are studied.It is indicated the water-absorbing swelling process is mainly caused by the difference in water osmotic pressure and Na+concentration inside and outside the cross-linked molecular structure of the resin,which is not only consistent with the quasi-secondary kinetic model,but also with the Fick diffusion model. 展开更多
关键词 super absorbent resin swelling kinetics water absorption graft copolymerization hydroxypropyl methyl cellulose
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Total ionizing dose effect modeling method for CMOS digital-integrated circuit
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作者 Bo Liang Jin-Hui Liu +3 位作者 Xiao-Peng Zhang Gang Liu Wen-Dan Tan Xin-Dan Zhang 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第2期32-46,共15页
Simulating the total ionizing dose(TID)of an electrical system using transistor-level models can be difficult and expensive,particularly for digital-integrated circuits(ICs).In this study,a method for modeling TID eff... Simulating the total ionizing dose(TID)of an electrical system using transistor-level models can be difficult and expensive,particularly for digital-integrated circuits(ICs).In this study,a method for modeling TID effects in complementary metaloxide semiconductor(CMOS)digital ICs based on the input/output buffer information specification(IBIS)was proposed.The digital IC was first divided into three parts based on its internal structure:the input buffer,output buffer,and functional area.Each of these three parts was separately modeled.Using the IBIS model,the transistor V-I characteristic curves of the buffers were processed,and the physical parameters were extracted and modeled using VHDL-AMS.In the functional area,logic functions were modeled in VHDL according to the data sheet.A golden digital IC model was developed by combining the input buffer,output buffer,and functional area models.Furthermore,the golden ratio was reconstructed based on TID experimental data,enabling the assessment of TID effects on the threshold voltage,carrier mobility,and time series of the digital IC.TID experiments were conducted using a CMOS non-inverting multiplexer,NC7SZ157,and the results were compared with the simulation results,which showed that the relative errors were less than 2%at each dose point.This confirms the practicality and accuracy of the proposed modeling method.The TID effect model for digital ICs developed using this modeling technique includes both the logical function of the IC and changes in electrical properties and functional degradation impacted by TID,which has potential applications in the design of radiation-hardening tolerance in digital ICs. 展开更多
关键词 CMOS digital-integrated circuit Total ionizing dose IBIS model Behavior-physical hybrid model Physical parameters
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Establishment of NaLuF_(4):15%Tb-based low dose X-PDT agent and its application on efficient antitumor therapy
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作者 Yi Tian Zhiguang Fu +7 位作者 Xiaosheng Zhu Chunjing Zhan Jinwei Hu Li Fan Chaojun Song Qian Yang Yu Wang Mei Shi 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第3期599-610,共12页
X-ray excited photodynamic therapy(X-PDT)is the bravo answer of photodynamic therapy(PDT)for deep-seated tumors,as it employs X-ray as the irradiation source to overcome the limitation of light penetration depth.Howev... X-ray excited photodynamic therapy(X-PDT)is the bravo answer of photodynamic therapy(PDT)for deep-seated tumors,as it employs X-ray as the irradiation source to overcome the limitation of light penetration depth.However,high X-ray irradiation dose caused organ lesions and side effects became the major barrier to X-PDT application.To address this issue,this work employed a classic-al co-precipitation reaction to synthesize NaLuF_(4):15%Tb^(3+)(NLF)with an average particle size of(23.48±0.91)nm,which was then coupled with the photosensitizer merocyanine 540(MC540)to form the X-PDT system NLF-MC540 with high production of singlet oxygen.The system could induce antitumor efficacy to about 24%in relative low dose X-ray irradiation range(0.1-0.3 Gy).In vivo,when NLF-MC540 irradiated by 0.1 Gy X-ray,the tumor inhibition percentage reached 89.5%±5.7%.The therapeutic mechanism of low dose X-PDT was found.A significant increase of neutrophils in serum was found on the third day after X-PDT.By immunohistochemical staining of tumor sections,the Ly6G^(+),CD8^(+),and CD11c^(+)cells infiltrated in the tumor microenvironment were studied.Utilizing the bilat-eral tumor model,the NLF-MC540 with 0.1 Gy X-ray irradiation could inhibit both the primary tumor and the distant tumor growth.De-tected by enzyme linked immunosorbent assay(ELISA),two cytokines IFN-γand TNF-αin serum were upregulated 7 and 6 times than negative control,respectively.Detected by enzyme linked immune spot assay(ELISPOT),the number of immune cells attributable to the IFN-γand TNF-αlevels in the group of low dose X-PDT were 14 and 6 times greater than that in the negative control group,respectively.Thus,it conclude that low dose X-PDT system could successfully upregulate the levels of immune cells,stimulate the secretion of cy-tokines(especially IFN-γand TNF-α),activate antitumor immunity,and finally inhibit colon tumor growth. 展开更多
关键词 X-ray excited photodynamic therapy singlet oxygen low dose X-Ray irradiation efficient antitumor therapy anti-tumor immunity
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Normalized glandular dose coefficients for digital breast tomosynthesis using detailed Chinese breast models
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作者 Jia-Hao Wang Rui Qiu +4 位作者 An-Kang Hu Ye-Qi Liu Zhen Wu Hui Zhang Jun-Li Li 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第5期42-59,共18页
The rise in breast cancer diagnoses among Chinese women has necessitated the use of X-ray breast screening,which carries a radiation risk.This study aimed to provide a dosimetry protocol for the Chinese female populat... The rise in breast cancer diagnoses among Chinese women has necessitated the use of X-ray breast screening,which carries a radiation risk.This study aimed to provide a dosimetry protocol for the Chinese female population to replace the traditional standard that utilizes simplified breast models,for the accurate estimation of the mean glandular dose of a patient undergoing digital breast tomosynthesis(DBT).The first set of detailed Chinese female breast models and representative breast parameters was constructed.Considering backscatter radiation and computational efficiency,we improved the combination of these models and the Chinese reference adult female whole-body voxel phantom.Image acquisition for four commercial DBT systems that are widely employed in China was simulated using the Monte Carlo method to obtain the normalized glandular dose coefficients of DBT(D_(gN)^(DBT))and the glandular depth dose(D_(g)^(dep)(z))for different breast characteristics and X-ray spectra.We calculated a series of D_(gN)^(DBT) values for breasts with different percentage mass glandularities(5%,25%,50%,75%,and 100%)and compressed breast thicknesses(2,3,4,5,6,and 7 cm)at various tube potentials(25,28,30,32,35,and 49 kV)and target/filter combinations(W/Rh,W/Al,Mo/Mo,Rh/Rh,and Rh/Ag).The parameter dependence of the breast characteristics and beam conditions on D_(gN)^(DBT) in detailed breast models was investigated.The D_(gN)^(DBT) results were 14.6-51.0%lower than those of the traditional dosimetry standard in China.The difference in D_(gN)^(DBT) was mainly due to a decrease in the depth of the main energy deposition area caused by the glandular distribution along the depth direction.The results obtained in this study may be used to improve breast dosimetry in China and provide more detailed information on risk assessment during DBT. 展开更多
关键词 Digital breast tomosynthesis Normalized glandular dose coefficients Detailed breast model Monte Carlo simulation
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A low-profile metamaterial absorber with ultrawideband reflectionless and wide-angular stability
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作者 Feihong Lin Zhongming Yan +3 位作者 Ping Wang Yu Wang Hongcheng Zhou Haoran Lu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期258-268,共11页
An ultrawideband reflectionless metamaterial absorber(MA)is proposed by replacing the metallic ground with the complementary split-ring resonator(CSRR)structure.The proposed MA exhibits-10 d B reflectivity spectrum fr... An ultrawideband reflectionless metamaterial absorber(MA)is proposed by replacing the metallic ground with the complementary split-ring resonator(CSRR)structure.The proposed MA exhibits-10 d B reflectivity spectrum from 1 GHz to 20 GHz,which maintains more than 90%absorption from 1.5 GHz to20 GHz.Furthermore,it achieves angle stability for TE and TM polarization at oblique incident angles up to 40°and 65°,respectively.To achieve broadband absorption spectrum,we have adopted a single-layer high-impedance surface(HIS)loaded with a double-layer magnetic material(MM)structure.To further realize the RCS reduction into a lower frequency range,we have employed the scattering cancellation technology into the traditional metallic ground.Finally,we have fabricated a sample exhibiting the 10 d B RCS reduction from 1 GHz to 20 GHz with a thickness of 10 mm.Measurement and simulation results confirm that the proposed MA exhibits excellent comprehensive performance,making it suitable for many practical applications. 展开更多
关键词 Metamaterial absorber(MA) Magnetic material(MM) High-impedance surface(HIS) Scattering cancellation technology ULTRAWIDEBAND Wide-angular stable
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