Disulfides were reduced by the Sm/NiCl2 or Sin/NiCI_2 6H_2O system to generate thiolateanion. which reacted further with anhydrides or acyl chlorides to afford thiolesters in good yieldsunder mild and neutral conditions.
Phenylthiotrimethylsilane is reduced hy samarium diiodide to yield samarium phenylthiolate. This new thiolate anion species reacts with acyl chlorides mildly to give thiolesters in good yields.
α-Selenoesters and α-thiolesters are synthesized via reactions of α-bromoesters with diselenides and disulfides promoted by Sm/SbCl3 system in aqueous media in moderate to good yields.
Copper catalyzed asymmetric formal [3＋2] cycloaddition of propargylic esters toβ‐keto phospho‐nates for the synthesis of chiral phosphonylated 2,3‐dihydrofurans was developed. By using a bulky and structurally ri...Copper catalyzed asymmetric formal [3＋2] cycloaddition of propargylic esters toβ‐keto phospho‐nates for the synthesis of chiral phosphonylated 2,3‐dihydrofurans was developed. By using a bulky and structurally rigid tridentate ketimine P,N,N ligand, a series of optically active phosphonylated 2,3‐dihydrofurans were prepared in high yield and up to 92%ee.展开更多
By the addition of rice wine koji, enhancement of the reactivity was observed for the baker＇s yeast reduction of β-keto esters into （S）-β-hydroxy esters with high enantiomeric purity （73-98%）.
An efficient procedure for the synthesis ofβ-keto esters from the reaction of aldehydes and ethyl diazoacetate catalyzed by iodine at room temperature under solvent-free conditions has been described. The catalytic p...An efficient procedure for the synthesis ofβ-keto esters from the reaction of aldehydes and ethyl diazoacetate catalyzed by iodine at room temperature under solvent-free conditions has been described. The catalytic procedure has the advantages of easily available catalyst, mild reaction conditions, high yields, and easy work-up.展开更多
An efficient synthetic method was developed to synthesize 2-substituted benzimidazoles and benzo- xazoles with β-keto esters as starting materials under mild reaction conditions, during which other functional groups ...An efficient synthetic method was developed to synthesize 2-substituted benzimidazoles and benzo- xazoles with β-keto esters as starting materials under mild reaction conditions, during which other functional groups are bearable from reactants to products.展开更多
文摘Disulfides were reduced by the Sm/NiCl2 or Sin/NiCI_2 6H_2O system to generate thiolateanion. which reacted further with anhydrides or acyl chlorides to afford thiolesters in good yieldsunder mild and neutral conditions.
文摘Phenylthiotrimethylsilane is reduced hy samarium diiodide to yield samarium phenylthiolate. This new thiolate anion species reacts with acyl chlorides mildly to give thiolesters in good yields.
文摘α-Selenoesters and α-thiolesters are synthesized via reactions of α-bromoesters with diselenides and disulfides promoted by Sm/SbCl3 system in aqueous media in moderate to good yields.
基金supported by the National Natural Science Foundation of China (21403022,21572226)the Natural Science Foundation of Liaoning Province of China (2015020194)~~
文摘Copper catalyzed asymmetric formal [3＋2] cycloaddition of propargylic esters toβ‐keto phospho‐nates for the synthesis of chiral phosphonylated 2,3‐dihydrofurans was developed. By using a bulky and structurally rigid tridentate ketimine P,N,N ligand, a series of optically active phosphonylated 2,3‐dihydrofurans were prepared in high yield and up to 92%ee.
文摘By the addition of rice wine koji, enhancement of the reactivity was observed for the baker＇s yeast reduction of β-keto esters into （S）-β-hydroxy esters with high enantiomeric purity （73-98%）.
基金Supported by the Special Scientific Research Project of Shaanxi Education Commission(No.08JZ09) the Science Re-search Foundation of Baoji University of Arts and Sciences, China(No.ZK064)
文摘An efficient procedure for the synthesis ofβ-keto esters from the reaction of aldehydes and ethyl diazoacetate catalyzed by iodine at room temperature under solvent-free conditions has been described. The catalytic procedure has the advantages of easily available catalyst, mild reaction conditions, high yields, and easy work-up.
基金Supported by the National Natural Science Foundation of China(No.20874105)the Foundation of Hebei Education Department China(No.2010268)
文摘An efficient synthetic method was developed to synthesize 2-substituted benzimidazoles and benzo- xazoles with β-keto esters as starting materials under mild reaction conditions, during which other functional groups are bearable from reactants to products.
