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Prescribed Performance Tracking Control of Time-Delay Nonlinear Systems With Output Constraints 被引量:1
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作者 Jin-Xi Zhang Kai-Di Xu Qing-Guo Wang 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第7期1557-1565,共9页
The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requ... The problem of prescribed performance tracking control for unknown time-delay nonlinear systems subject to output constraints is dealt with in this paper. In contrast with related works, only the most fundamental requirements, i.e., boundedness and the local Lipschitz condition, are assumed for the allowable time delays. Moreover, we focus on the case where the reference is unknown beforehand, which renders the standard prescribed performance control designs under output constraints infeasible. To conquer these challenges, a novel robust prescribed performance control approach is put forward in this paper.Herein, a reverse tuning function is skillfully constructed and automatically generates a performance envelop for the tracking error. In addition, a unified performance analysis framework based on proof by contradiction and the barrier function is established to reveal the inherent robustness of the control system against the time delays. It turns out that the system output tracks the reference with a preassigned settling time and good accuracy,without constraint violations. A comparative simulation on a two-stage chemical reactor is carried out to illustrate the above theoretical findings. 展开更多
关键词 Nonlinear systems output constraints prescribed performance reference tracking time delays
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法舒地尔缓解β-淀粉样蛋白1-42诱导的SH-SY5Y细胞凋亡
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作者 郭敏芳 张慧宇 +3 位作者 章培军 苏琴 贾思玮 尉杰忠 《中国组织工程研究》 CAS 北大核心 2025年第23期4939-4946,共8页
背景:法舒地尔对阿尔茨海默病小鼠脑内的线粒体动力学有调节作用,并且可以抑制神经炎症,但能否调节线粒体自噬和NLRP3炎症小体进而减轻β-淀粉样蛋白毒性尚不清楚。目的:探究法舒地尔对β-淀粉样蛋白1-42诱导的人源神经母细胞瘤细胞株SH... 背景:法舒地尔对阿尔茨海默病小鼠脑内的线粒体动力学有调节作用,并且可以抑制神经炎症,但能否调节线粒体自噬和NLRP3炎症小体进而减轻β-淀粉样蛋白毒性尚不清楚。目的:探究法舒地尔对β-淀粉样蛋白1-42诱导的人源神经母细胞瘤细胞株SH-SY5Y凋亡和线粒体自噬以及NLRP3炎症小体的调节作用。方法:将SH-SY5Y细胞接种于孔板内,细胞贴壁后分3组干预:对照组不加入任何药物,模型组加入20μmol/L β-淀粉样蛋白1-42,法舒地尔组同时加入20μmol/L β-淀粉样蛋白1-42与15 mg/L法舒地尔,干预24 h后,采用MTT法检测细胞活性,TUNEL染色检测细胞凋亡,qRT-PCR和Western blot检测凋亡相关蛋白表达,免疫荧光染色和Western blot检测线粒体自噬相关蛋白表达,免疫荧光染色和Western blot检测NLRP3炎症小体相关蛋白表达。结果与结论:(1)与对照组比较,模型组细胞活性降低、凋亡率升高(P<0.05);与模型组比较,法舒地尔组细胞活性升高、凋亡率降低(P<0.05);(2)qRT-PCR和Western blot检测结果显示,与对照组比较,模型组细胞Bax mRNA与蛋白表达升高(P<0.05),Bcl-2 mRNA与蛋白表达降低(P<0.05);与模型组比较,法舒地尔组细胞Bax mRNA与蛋白表达降低(P<0.05),Bcl-2 mRNA与蛋白表达升高(P<0.05);(3)免疫荧光染色和Western blot检测结果显示,与对照组相比,模型组细胞PINK1、帕金森病蛋白和LC3蛋白表达降低(P<0.05),p62蛋白表达升高(P<0.05);与模型组相比,法舒地尔组细胞PINK1、帕金森病蛋白和LC3蛋白表达升高(P<0.05),p62蛋白表达降低(P<0.05);(4)免疫荧光染色和Western blot检测结果显示,与对照组相比,模型组细胞NLRP3、ASC、Caspase-1和白细胞介素1β蛋白表达升高(P<0.05);与模型组相比,法舒地尔组细胞NLRP3、ASC、Caspase-1和白细胞介素1β蛋白表达降低(P<0.05);(5)结果表明,法舒地尔可以减轻β-淀粉样蛋白1-42诱导的SH-SY5Y细胞凋亡,其机制可能与激活线粒体自噬且抑制NLRP3炎症小体激活有关。 展开更多
关键词 法舒地尔 Β-淀粉样蛋白 神经细胞 细胞凋亡 线粒体自噬 炎症小体
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ANGPTL4 TSP-1及CyPA与脑卒中后癫痫患者认知功能的关系
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作者 高灵利 方建 +2 位作者 李晓晖 李延红 耿智凡 《中国实用神经疾病杂志》 2025年第1期63-67,共5页
目的探讨血管生成素样蛋白4(ANGPTL4)、凝血酶敏感蛋白-1(TSP-1)、亲环素A(CyPA与脑卒中后癫痫患者认知功能的关系。方法选取2021-01—2022-12河南大学第一附属医院神经内科收治的100例脑卒中后癫痫病例进行观察,按简易精神状态量表(MM... 目的探讨血管生成素样蛋白4(ANGPTL4)、凝血酶敏感蛋白-1(TSP-1)、亲环素A(CyPA与脑卒中后癫痫患者认知功能的关系。方法选取2021-01—2022-12河南大学第一附属医院神经内科收治的100例脑卒中后癫痫病例进行观察,按简易精神状态量表(MMSE)划分认知障碍标准将患者分为认知障碍组(50例)和认知正常组(50例),应用酶联免疫吸附试验(ELISA)检测2组患者的血清ANGPTL4、TSP-1、CyPA水平,MMSE量表测评2组患者的认知功能。结果与认知正常组比较,认知障碍组患者MMSE评分降低,ANGPTL4、TSP-1、CyPA水平升高(P<0.05);与轻度认知障碍患者比较,中度认知障碍患者血清ANGPTL4、TSP-1、CyPA水平升高(P<0.05);与中度认知障碍患者比较,重度认知障碍患者血清ANGPTL4、TSP-1、CyPA水平升高(P<0.05)。在脑卒中后癫痫患者中,血清ANGPTL4、TSP-1、Cy PA与MMSE评分各维度均呈负相关(P<0.05)。结论脑卒中后癫痫会降低MMSE评分,提高患者血清ANGPTL4、TSP-1、CyPA水平。ANGPTL4、TSP-1、CyPA水平越高,患者认知功能障碍越严重。 展开更多
关键词 脑卒中后癫痫 血管生成素样蛋白4 凝血酶敏感蛋白-1 亲环素A 认知功能
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lncRNA-BBOX1-2通过调控成纤维细胞生长因子受体1促进胃癌的发生和发展
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作者 孙颖 顾玮 +1 位作者 王吉 郑雄 《安徽医药》 CAS 2025年第1期57-62,I0002,共7页
目的探讨长链非编码RNA(long non-coding RNA,lncRNA)BBOX1-2通过调控成纤维细胞生长因子受体1(fibroblast growth factor receptor 1,FGFR1)对胃癌的发生发展机制的影响。方法回顾性选取2017年4月至2019年1月于上海交通大学医学院附属... 目的探讨长链非编码RNA(long non-coding RNA,lncRNA)BBOX1-2通过调控成纤维细胞生长因子受体1(fibroblast growth factor receptor 1,FGFR1)对胃癌的发生发展机制的影响。方法回顾性选取2017年4月至2019年1月于上海交通大学医学院附属瑞金医院卢湾分院接受胃癌根治术30例病人肿瘤组织及癌旁相应正常组织作为研究对象,采用实时定量PCT(real-time PCR,RT-PCR)检测lncRNA-BBOX1-2和FGFR1表达;si-linc-BBOX1-2转染SGC-7901细胞后,通过蛋白质印迹法/细胞存活率分析(MTT)、细胞迁移和侵袭(Transwell)实验、细胞划痕、平板克隆一系列生物学功能实验,检测肿瘤细胞生物学功能及FGFR1表达的变化。结果胃癌组织中的lncRNA-BBOX1-2(3.68±0.58比1.15±0.11)和FGFR1(4.26±0.71比1.19±0.18)表达显著高于癌旁正常组织(P<0.05);si-linc-BBOX1-2转染SGC-7901细胞后,FGFR1表达下调,细胞活力、迁移、侵袭和生存能力明显下降。结论LincRNA-BBOX1-2可通过调控FGFR1的表达介导胃癌细胞的增殖、凋亡、迁移和侵袭,可能为胃癌的治疗提供了新的靶点和潜在的生物学标志物。 展开更多
关键词 胃肿瘤 长链非编码RNA BBOX1-2 成纤维细胞生长因子受体1 调控 增殖 凋亡
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自旋-轨道耦合作用下极化激元凝聚中的调制不稳定性
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作者 陈海军 《原子与分子物理学报》 CAS 北大核心 2025年第6期136-143,共8页
利用线性稳定性分析方法,对存在自旋-轨道耦合(SOS)作用的二维极化激元玻色-爱因斯坦凝聚(BEC)系统中的调制不稳定性(MI)进行了研究.分析了组分内部,组分之间以及SOC相互作用对系统调制不稳定性的影响.结果显示,当系统内部不存在SOC作用... 利用线性稳定性分析方法,对存在自旋-轨道耦合(SOS)作用的二维极化激元玻色-爱因斯坦凝聚(BEC)系统中的调制不稳定性(MI)进行了研究.分析了组分内部,组分之间以及SOC相互作用对系统调制不稳定性的影响.结果显示,当系统内部不存在SOC作用,组分之间的相互作用为0,组分内部存在排斥作用时,不会出现调制不稳定性,组分内部存在吸引作用时,会出现调制不稳定性,并且调制不稳定性区间长度随吸引作用的增强而增加;组分之间相互作用不为0时,组分之间的相互作用以平方形式出现,其正负不会对调制不稳定性产生实质性影响.存在SOC相互作用时,SOC相互作用会引起增益谱曲线的不规则振荡,破坏原来的调制不稳定性区间. 展开更多
关键词 极化激元凝聚 调制不稳定性 自旋-轨道耦合 双分量
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双偶氮苯-二苯并[b,i]噻蒽-[2,3-b]苯-5,7,12,14-四酮衍生物分子的二阶非线性光学性质 被引量:1
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作者 张宇红 李博 +4 位作者 陈自然 李渊 徐友辉 张莉萍 何旭东 《原子与分子物理学报》 CAS 北大核心 2025年第2期15-23,共9页
使用密度泛函理论(DFT)M06-2X方法、采用6-311+g(d,p)基组,分别对26个双偶氮-二苯并[b,i]噻蒽-[2,3-b]苯-5,7,12,14-四酮衍生物分子进行结构优化与频率计算;使用含时密度泛函理论(TD-DFT)TD-M06-2X方法计算了a1~d6分子的前线分子轨道与... 使用密度泛函理论(DFT)M06-2X方法、采用6-311+g(d,p)基组,分别对26个双偶氮-二苯并[b,i]噻蒽-[2,3-b]苯-5,7,12,14-四酮衍生物分子进行结构优化与频率计算;使用含时密度泛函理论(TD-DFT)TD-M06-2X方法计算了a1~d6分子的前线分子轨道与电子吸收光谱,采用有效场FF方法研究了二阶非线性光学性质(NLO).研究结果表明,26个噻蒽四酮类衍生物分子的能隙在1.33—2.02 eV范围,归属于有机半导体;最低能量吸收峰波长在601.8~609.5nm范围;在增大分子的二阶非线性光学系数β_(μ)(或β_(0))值方面,含相同偶氮苯基团或含不同偶氮苯基团分别引入到二苯并[b,i]噻蒽-[2,3-b]苯-5,7,12,14-四酮分子两侧的2,10位优于2,9位,在2,10位分别端接含推、拉基团的偶氮苯优于含相同给电子基团的偶氮苯.在偶氮苯苯环对位分别端接强吸电子基(-NO_(2))与强供电子基(如-N(CH_(3))_(2)、-N(Ph)_(3)、-N-苯基咔唑等)可增强体系的二阶非线性光学性能,获得性能良好的非线性光学材料. 展开更多
关键词 双偶氮 二苯并[b i]噻蒽-[2 3-b]苯-5 7 12 14-四酮 密度泛函理论 电子吸收光谱 二阶非线性光学性质
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基于TLR4 NF-κB通路-神经相关因子探究依达拉奉对急性脑梗死患者炎症反应与神经损伤的保护机制
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作者 李莉 姜雪 +1 位作者 姜荣格 李恳 《中国实用神经疾病杂志》 2025年第1期47-52,共6页
目的基于Toll样受体4(TLR4)核因子-κB(NF-κB)通路-神经相关因子探究依达拉奉对急性脑梗死(ACI)患者炎症反应与神经损伤的保护机制。方法选取2020-07—2023-07保定市第一中心医院收治的110例ACI患者,以随机数字表法分为观察组、对照组,... 目的基于Toll样受体4(TLR4)核因子-κB(NF-κB)通路-神经相关因子探究依达拉奉对急性脑梗死(ACI)患者炎症反应与神经损伤的保护机制。方法选取2020-07—2023-07保定市第一中心医院收治的110例ACI患者,以随机数字表法分为观察组、对照组,各55例,对照组给予阿替普酶溶栓,观察组给予阿替普酶溶栓联合依达拉奉治疗。比较2组疗效、神经功能[美国国立卫生研究院卒中量表(NIHSS)评分、改良Rankin评分]、TLR4 NF-κB通路指标(TLR4、NF-κB)、神经损伤相关因子[神经元特异性烯醇化酶(NSE)、中枢神经特异性蛋白(S-100β)、脑源性神经营养因子(BDNF)]、TLR4 NF-κB通路相关炎症因子[白介素-1β(IL-1β)、超敏C反应蛋白(hs-CRP)、肿瘤坏死因子(TNF-α)、五聚素3(PTX3)、脂蛋白相关磷脂酶A2(Lp-PLA2)]。结果观察组总有效率96.36%,高于对照组的83.64%(P<0.05)。治疗1、2周观察组NIHSS评分、改良Rankin评分均低于对照组(P<0.05),观察组TLR4、NF-κB均低于对照组(P<0.05)。相较于治疗前,2组治疗1、2周后S-100β、NSE水平明显下降,BDNF水平明显升高,观察组S-100β、NSE水平均低于对照组,BDNF水平高于对照组(P<0.05)。相较于治疗前,2组治疗1、2周后IL-1β、hs-CRP、TNF-α、PTX3、Lp-PLA2水平均明显下降,观察组IL-1β、hs-CRP、TNF-α、PTX3、Lp-PLA2水平均低于对照组(P<0.05)。结论依达拉奉对ACI患者的疗效显著,有利于缓解炎症反应,改善神经损伤,其保护机制可能与TLR4 NF-κB通路调控神经损伤、炎症反应相关因子有关。 展开更多
关键词 急性脑梗死 TOLL样受体4 核因子-ΚB 依达拉奉 TLR4 NF-κB通路
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Characterization and quantification of multi-field coupling in lithium-ion batteries under mechanical constraints
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作者 Xue Cai Caiping Zhang +3 位作者 Zeping Chen Linjing Zhang Dirk Uwe Sauer Weihan Li 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第8期364-379,I0009,共17页
The safety and durability of lithium-ion batteries under mechanical constraints depend significantly on electrochemical,thermal,and mechanical fields in applications.Characterizing and quantifying the multi-field coup... The safety and durability of lithium-ion batteries under mechanical constraints depend significantly on electrochemical,thermal,and mechanical fields in applications.Characterizing and quantifying the multi-field coupling behaviors requires interdisciplinary efforts.Here,we design experiments under mechanical constraints and introduce an in-situ analytical framework to clarify the complex interaction mechanisms and coupling degrees among multi-physics fields.The proposed analytical framework integrates the parameterization of equivalent models,in-situ mechanical analysis,and quantitative assessment of coupling behavior.The results indicate that the significant impact of pressure on impedance at low temperatures results from the diffusion-controlled step,enhancing kinetics when external pressure,like 180 to 240 k Pa at 10℃,is applied.The diversity in control steps for the electrochemical reaction accounts for the varying impact of pressure on battery performance across different temperatures.The thermal expansion rate suggests that the swelling force varies by less than 1.60%per unit of elevated temperature during the lithiation process.By introducing a composite metric,we quantify the coupling correlation and intensity between characteristic parameters and physical fields,uncovering the highest coupling degree in electrochemical-thermal fields.These results underscore the potential of analytical approaches in revealing the mechanisms of interaction among multi-fields,with the goal of enhancing battery performance and advancing battery management. 展开更多
关键词 Lithium-ion battery Muti-field coupling Mechanical constraints Interaction mechanisms Quantitative analysis
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Probabilistic-Ellipsoid Hybrid Reliability Multi-Material Topology Optimization Method Based on Stress Constraint
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作者 Zibin Mao Qinghai Zhao Liang Zhang 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第7期757-792,共36页
This paper proposes a multi-material topology optimization method based on the hybrid reliability of the probability-ellipsoid model with stress constraint for the stochastic uncertainty and epistemic uncertainty of m... This paper proposes a multi-material topology optimization method based on the hybrid reliability of the probability-ellipsoid model with stress constraint for the stochastic uncertainty and epistemic uncertainty of mechanical loads in optimization design.The probabilistic model is combined with the ellipsoidal model to describe the uncertainty of mechanical loads.The topology optimization formula is combined with the ordered solid isotropic material with penalization(ordered-SIMP)multi-material interpolation model.The stresses of all elements are integrated into a global stress measurement that approximates the maximum stress using the normalized p-norm function.Furthermore,the sequential optimization and reliability assessment(SORA)is applied to transform the original uncertainty optimization problem into an equivalent deterministic topology optimization(DTO)problem.Stochastic response surface and sparse grid technique are combined with SORA to get accurate information on the most probable failure point(MPP).In each cycle,the equivalent topology optimization formula is updated according to the MPP information obtained in the previous cycle.The adjoint variable method is used for deriving the sensitivity of the stress constraint and the moving asymptote method(MMA)is used to update design variables.Finally,the validity and feasibility of the method are verified by the numerical example of L-shape beam design,T-shape structure design,steering knuckle,and 3D T-shaped beam. 展开更多
关键词 Stress constraint probabilistic-ellipsoid hybrid topology optimization reliability analysis multi-material design
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Dynamic characteristics of multi-span spinning beams with elastic constraints under an axial compressive force
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作者 Xiaodong GUO Zhu SU Lifeng WANG 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第2期295-310,共16页
A theoretical model for the multi-span spinning beams with elastic constraints under an axial compressive force is proposed.The displacement and bending angle functions are represented through an improved Fourier seri... A theoretical model for the multi-span spinning beams with elastic constraints under an axial compressive force is proposed.The displacement and bending angle functions are represented through an improved Fourier series,which ensures the continuity of the derivative at the boundary and enhances the convergence.The exact characteristic equations of the multi-span spinning beams with elastic constraints under an axial compressive force are derived by the Lagrange equation.The efficiency and accuracy of the present method are validated in comparison with the finite element method(FEM)and other methods.The effects of the boundary spring stiffness,the number of spans,the spinning velocity,and the axial compressive force on the dynamic characteristics of the multi-span spinning beams are studied.The results show that the present method can freely simulate any boundary constraints without modifying the solution process.The elastic range of linear springs is larger than that of torsion springs,and it is not affected by the number of spans.With an increase in the axial compressive force,the attenuation rate of the natural frequency of a spinning beam with a large number of spans becomes larger,while the attenuation rate with an elastic boundary is lower than that under a classic simply supported boundary. 展开更多
关键词 multi-span spinning beam elastic constraint improved Fourier series free vibration semi-analytical solution
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Dynamic Constraint-Driven Event-Triggered Control of Strict-Feedback Systems Without Max/Min Values on Irregular Constraints
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作者 Zhuwu Shao Yujuan Wang +1 位作者 Zeqiang Li Yongduan Song 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期569-580,共12页
This work proposes an event-triggered adaptive control approach for a class of uncertain nonlinear systems under irregular constraints.Unlike the constraints considered in most existing papers,here the external irregu... This work proposes an event-triggered adaptive control approach for a class of uncertain nonlinear systems under irregular constraints.Unlike the constraints considered in most existing papers,here the external irregular constraints are considered and a constraints switching mechanism(CSM)is introduced to circumvent the difficulties arising from irregular output constraints.Based on the CSM,a new class of generalized barrier functions are constructed,which allows the control results to be independent of the maximum and minimum values(MMVs)of constraints and thus extends the existing results.Finally,we proposed a novel dynamic constraint-driven event-triggered strategy(DCDETS),under which the stress on signal transmission is reduced greatly and no constraints are violated by making a dynamic trade-off among system state,external constraints,and inter-execution intervals.It is proved that the system output is driven to close to the reference trajectory and the semi-global stability is guaranteed under the proposed control scheme,regardless of the external irregular output constraints.Simulation also verifies the effectiveness and benefits of the proposed method. 展开更多
关键词 Adaptive control dynamic constraint-driven event-triggered control irregular output constraints nonlinear strict-feed-back systems
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Constraints Separation Based Evolutionary Multitasking for Constrained Multi-Objective Optimization Problems
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作者 Kangjia Qiao Jing Liang +4 位作者 Kunjie Yu Xuanxuan Ban Caitong Yue Boyang Qu Ponnuthurai Nagaratnam Suganthan 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第8期1819-1835,共17页
Constrained multi-objective optimization problems(CMOPs)generally contain multiple constraints,which not only form multiple discrete feasible regions but also reduce the size of optimal feasible regions,thus they prop... Constrained multi-objective optimization problems(CMOPs)generally contain multiple constraints,which not only form multiple discrete feasible regions but also reduce the size of optimal feasible regions,thus they propose serious challenges for solvers.Among all constraints,some constraints are highly correlated with optimal feasible regions;thus they can provide effective help to find feasible Pareto front.However,most of the existing constrained multi-objective evolutionary algorithms tackle constraints by regarding all constraints as a whole or directly ignoring all constraints,and do not consider judging the relations among constraints and do not utilize the information from promising single constraints.Therefore,this paper attempts to identify promising single constraints and utilize them to help solve CMOPs.To be specific,a CMOP is transformed into a multitasking optimization problem,where multiple auxiliary tasks are created to search for the Pareto fronts that only consider a single constraint respectively.Besides,an auxiliary task priority method is designed to identify and retain some high-related auxiliary tasks according to the information of relative positions and dominance relationships.Moreover,an improved tentative method is designed to find and transfer useful knowledge among tasks.Experimental results on three benchmark test suites and 11 realworld problems with different numbers of constraints show better or competitive performance of the proposed method when compared with eight state-of-the-art peer methods. 展开更多
关键词 Constrained multi-objective optimization(CMOPs) evolutionary multitasking knowledge transfer single constraint.
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Stress tensor determination by modified hydraulic tests on pre-existing fractures:Method and stress constraints
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作者 Guiyun Gao Chenghu Wang Ke Gao 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第5期1637-1648,共12页
The hydraulic testing of pre-existing fractures(HTPF)is one of the most promising in situ stress measurement methods,particularly for three-dimensional stress tensor determination.However,the stress tensor determinati... The hydraulic testing of pre-existing fractures(HTPF)is one of the most promising in situ stress measurement methods,particularly for three-dimensional stress tensor determination.However,the stress tensor determination based on the HTPF method requires at least six tests or a minimum of 14-15 tests(under different conditions)for reliable results.In this study,we modified the HTPF method by considering the shear stress on each pre-existing fracture,which increased the number of equations for the stress tensor determination and decreased the number of tests required.Different shear stresses were attributed to different fractures by random sampling;therefore,the stress tensors were obtained by searching for the optimal solution using the least squares criterion based on the Monte Carlo method.Thereafter,we constrained the stress tensor based on the tensile strength criterion,compressive strength criterion,and vertical stress constraints.The inverted stress tensors were presented and analyzed based on the tensorial nature of the stress using the Euclidean mean stress tensor.Two stress-measurement campaigns in Weifang(Shandong Province,China)and Mercantour road tunnel(France)were implemented to highlight the validity and efficiency of the modified HTPF(M-HTPF)method.The results showed that the M-HTPF method can be applied for stress tensor inversion using only three to four tests on pre-existing fractures,neglecting the stress gradient.The inversion results were confined to relatively small distribution dispersions and were significantly reliable and stable due to the shear stresses on the fractures and the stress constraints employed.The M-HTPF method is highly feasible and efficient for complete stress tensor determination in a single borehole. 展开更多
关键词 Stress tensor Hydraulic tests on pre-existing fractures Mean stress Stress constraint Hydraulic fracturing
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Research on the navigation method of large-scale differential tail-control improvised guided munitions based on rotational speed constraints
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作者 Ning Liu Wenjiang Zhao +4 位作者 Yao Wang Kai Shen Zhong Su Wenhao Qi Yuedong Xie 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第8期155-170,共16页
In the process of launching guided projectile under the conventional system, it is difficult to effectively obtain the precise navigation parameters of the projectile in the high dynamic environment. Aiming at this pr... In the process of launching guided projectile under the conventional system, it is difficult to effectively obtain the precise navigation parameters of the projectile in the high dynamic environment. Aiming at this problem, this paper describes a new system of guided ammunition based on tail spin reduction. After analyzing the mechanism of the ammunition's tail spin reduction, a navigation method of large scale difference tail control simple guided ammunition based on speed constraint is proposed. In this method,the corresponding navigation constraints can be carried out by combining the rotation speed state of the ammunition itself, and the optimal solution of navigation parameters during the flight of the missile can be obtained by Extended Kalman Filter(EKF). Finally, the performance of the proposed method was verified by the simulation environment, and the hardware-in-the-loop simulation test and flight test were carried out to verify the performance of the method in the real environment. The experimental results show that the proposed method can achieve the optimal estimation of navigation parameters for simple guided ammunition with large-scale difference tail control. Under the conditions of simulation test and hardware-in-loop simulation test, the position and velocity errors calculated by the method in this paper converged. Under the condition of flight test, the spatial average error calculated by the method described in this paper is 6.17 m, and the spatial error of the final landing point is 3.50 m.Through this method, the accurate acquisition of navigation parameters in the process of projectile launching is effectively realized. 展开更多
关键词 Guided projectiles Tail spin reduction RPM constraints Combined navigation Extended Kalman filter(EKF)
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Energy-Saving Distributed Flexible Job Shop Scheduling Optimization with Dual Resource Constraints Based on Integrated Q-Learning Multi-Objective Grey Wolf Optimizer
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作者 Hongliang Zhang Yi Chen +1 位作者 Yuteng Zhang Gongjie Xu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第8期1459-1483,共25页
The distributed flexible job shop scheduling problem(DFJSP)has attracted great attention with the growth of the global manufacturing industry.General DFJSP research only considers machine constraints and ignores worke... The distributed flexible job shop scheduling problem(DFJSP)has attracted great attention with the growth of the global manufacturing industry.General DFJSP research only considers machine constraints and ignores worker constraints.As one critical factor of production,effective utilization of worker resources can increase productivity.Meanwhile,energy consumption is a growing concern due to the increasingly serious environmental issues.Therefore,the distributed flexible job shop scheduling problem with dual resource constraints(DFJSP-DRC)for minimizing makespan and total energy consumption is studied in this paper.To solve the problem,we present a multi-objective mathematical model for DFJSP-DRC and propose a Q-learning-based multi-objective grey wolf optimizer(Q-MOGWO).In Q-MOGWO,high-quality initial solutions are generated by a hybrid initialization strategy,and an improved active decoding strategy is designed to obtain the scheduling schemes.To further enhance the local search capability and expand the solution space,two wolf predation strategies and three critical factory neighborhood structures based on Q-learning are proposed.These strategies and structures enable Q-MOGWO to explore the solution space more efficiently and thus find better Pareto solutions.The effectiveness of Q-MOGWO in addressing DFJSP-DRC is verified through comparison with four algorithms using 45 instances.The results reveal that Q-MOGWO outperforms comparison algorithms in terms of solution quality. 展开更多
关键词 Distributed flexible job shop scheduling problem dual resource constraints energy-saving scheduling multi-objective grey wolf optimizer Q-LEARNING
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Secure symbol level precoding for cell-free network based on band-region constraint of the eavesdropper’s receiving signal
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作者 LI Zewen JIN Yong +2 位作者 FU Chunling PENG Xin HU Zhentao 《High Technology Letters》 EI CAS 2024年第3期304-309,共6页
A symbol level secure precoding scheme based on band-region constraint of the eavesdropper’s receiving signal is proposed to enhance the energy efficiency of cell-free multiple-input multiple-output(MIMO)networks in ... A symbol level secure precoding scheme based on band-region constraint of the eavesdropper’s receiving signal is proposed to enhance the energy efficiency of cell-free multiple-input multiple-output(MIMO)networks in the presence of an eavesdropper while guaranteeing the quality of service(QoS)of user and the security of system.Moreover,to lighten its high computational complexity,original problem is divided into several cascade sub-problems firstly,and then those sub-problems are handled by combining Lagrangian dual function and improved Hooke-Jeeves method together.Comparative ex-periment with other secure symbol-level precoding schemes demonstrate that proposed scheme can achieve the lower power consumption with almost same symbol error rate and QoS of user. 展开更多
关键词 cell-free symbol-level precoding(SLP) physical layer security(PLS) multi-ple-input multiple-output(MIMO) band-region constraint
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阿拉善-华北北缘晚古生代-早中生代岩浆作用:对古亚洲洋俯冲-闭合过程的制约
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作者 曾浩 宋东方 +1 位作者 肖文交 李普庆 《岩石学报》 SCIE EI CAS 北大核心 2025年第1期66-90,共25页
位于中亚造山带南部的阿拉善-华北北缘地区保存了丰富的晚古生代-早中生代岩浆记录,为理解古亚洲洋从俯冲至闭合的构造演化过程提供了关键信息。本文对位于内蒙古西部的甘其毛都地区的4个侵入体进行了岩相学、地球化学、锆石U-Pb年代学... 位于中亚造山带南部的阿拉善-华北北缘地区保存了丰富的晚古生代-早中生代岩浆记录,为理解古亚洲洋从俯冲至闭合的构造演化过程提供了关键信息。本文对位于内蒙古西部的甘其毛都地区的4个侵入体进行了岩相学、地球化学、锆石U-Pb年代学和Lu-Hf同位素分析。锆石U-Pb定年表明这些岩体分别形成于早二叠世(283±3Ma、273±5Ma、272±5Ma)和中三叠世(238±3Ma)。早二叠世岩体以石英闪长岩和闪长玢岩为主,富集轻稀土与大离子亲石元素,亏损高场强元素Nb、Ta等,Hf同位素显著亏损(-4.0~+15.6)。它们可能是由俯冲板片流体交代地幔楔部分熔融形成的基性岩浆经分离结晶演化而成。中三叠世侵入体为花岗闪长岩,轻重稀土元素强烈分异,锆石ε_(Hf)(t)值均为正值(+5.0~+8.5),可能代表了碰撞造山阶段新生下地壳物质部分熔融的产物。在此基础之上,本文系统收集并分析了阿拉善-华北北缘地区晚古生代-早中生代岩浆岩的时空分布规律与地球化学特征,以限定其构造背景与深部动力学过程。结合前人研究成果提出:石炭纪时期,古亚洲洋向南俯冲至阿拉善-华北克拉通之下并不断向北后撤;至早二叠世,俯冲板片转变为前进式俯冲,整体处于挤压环境,发育大规模岩浆活动与弧背前陆盆地;早-中三叠世,古亚洲洋闭合,阿拉善-华北克拉通沿索伦缝合带与北侧的中亚弧增生体系发生碰撞-拼贴。 展开更多
关键词 阿拉善 华北北缘 晚古生代-早中生代 古亚洲洋 俯冲-闭合
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Joint Beamforming Design for Dual-Functional Radar-Communication Systems Under Beampattern Gain Constraints
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作者 CHEN Guangyi ZHANG Ruoyu +2 位作者 REN Hong LIN Xu WU Wen 《ZTE Communications》 2024年第3期13-20,共8页
The joint beamforming design challenge for dual-functional radar-communication systems is addressed in this paper.The base station in these systems is tasked with simultaneously sending shared signals for both multi-u... The joint beamforming design challenge for dual-functional radar-communication systems is addressed in this paper.The base station in these systems is tasked with simultaneously sending shared signals for both multi-user communication and target sensing.The primary objective is to maximize the sum rate of multi-user communication,while also ensuring sufficient beampattern gain at particular angles that are of interest for sensing,all within the constraints of the transmit power budget.To tackle this complex non-convex problem,an effective algorithm that iteratively optimizes the joint beamformers is developed.This algorithm leverages the techniques of fractional programming and semidefinite relaxation to achieve its goals.The numerical results confirm the effectiveness of the proposed algorithm. 展开更多
关键词 dual-functional radar-communication joint beamforming design beampattern gain constraints semidefinite relaxation fractional programming
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青年缺血性脑卒中病人血清miR-218-5p、LASP1水平及其应用价值
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作者 亓超 李慧 +1 位作者 吴永亚 李晨曦 《安徽医药》 CAS 2025年第1期156-159,共4页
目的探究青年缺血性脑卒中(IS)病人血清微RNA-218-5p(miR-218-5p)、LIM和SH3蛋白1(LASP1)水平及其应用价值。方法选取2020年6月至2022年6月山东中医药大学附属医院收治的青年IS病人96例为IS组,对所有IS病人进行为期3个月的随访,按照改良... 目的探究青年缺血性脑卒中(IS)病人血清微RNA-218-5p(miR-218-5p)、LIM和SH3蛋白1(LASP1)水平及其应用价值。方法选取2020年6月至2022年6月山东中医药大学附属医院收治的青年IS病人96例为IS组,对所有IS病人进行为期3个月的随访,按照改良Rankin量表(mRS)评分进行分组,预后良好组68例(mRS评分≤2分)和预后不良组28例(mRS评分>2分)。选择同期在该院进行体检的健康志愿者96例为对照组。血清miR-218-5p、LASP1 mRNA水平检测采用实时荧光定量PCR(qRT-PCR);Pearson相关性分析血清miR-218-5p与LASP1 mRNA表达水平的关系。采用受试者操作特征曲线(ROC曲线)分析血清中miR-218-5p、LASP1 mRNA表达水平对IS预后评估的价值。结果与对照组相比,IS组白细胞计数、总胆固醇、三酰甘油、低密度脂蛋白胆固醇水平显著升高,高密度脂蛋白胆固醇水平显著降低(P<0.05);与对照组(1.03±0.11、1.01±0.11)相比,IS组血清中miR-218-5p水平0.88±0.09显著降低,LASP1 mRNA(1.12±0.12)水平显著升高(P<0.05)。IS病人血清miR-218-5p与LASP1 mRNA呈负相关(r=−0.73,P<0.001)。与预后良好组(0.94±0.10、1.05±0.11)相比,预后不良组血清中miR-218-5p(0.74±0.08)水平显著降低,LASP1 mRNA(1.28±0.13)水平显著升高(P<0.05)。ROC曲线显示,二者联合评估IS预后不良的AUC高于miR-218-5p、LASP1 mRNA单独预测的AUC值(Z=12.35,P<0.001;Z=6.60,P=0.010)。结论青年IS病人血清miR-218-5p较低,LASP1 mRNA较高,可用于评估青年IS病人的预后。 展开更多
关键词 卒中 脑梗死 青年 微核糖核酸-218-5p LIM和SH3蛋白1 预后
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气相色谱-离子迁移谱技术在食品真实性鉴别中的应用研究进展
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作者 张碧莹 隋雨萌 +4 位作者 张鑫 李永杰 孔保华 刘昊天 陈倩 《食品科学》 EI CAS 北大核心 2025年第1期227-236,共10页
气相色谱-离子迁移谱是一种灵敏的检测、鉴别和监测不同基质中痕量物质的分析技术,能够通过气相色谱和离子迁移谱对分析物质进行二次快速分离和高精准定性。由于气相色谱-离子迁移谱具有环保、使用便捷、操作简单及适用于工业大量连续... 气相色谱-离子迁移谱是一种灵敏的检测、鉴别和监测不同基质中痕量物质的分析技术,能够通过气相色谱和离子迁移谱对分析物质进行二次快速分离和高精准定性。由于气相色谱-离子迁移谱具有环保、使用便捷、操作简单及适用于工业大量连续检测等优点,近年来逐渐成为食品真实性鉴别的热门分析技术。本文主要介绍气相色谱-离子迁移谱的类型、结构、工作原理和分析方法,重点综述其在食品真实性鉴别中的应用,以期为食品真实性问题的解决提供理论参考。 展开更多
关键词 气相色谱-离子迁移谱 真实性鉴别 食品 应用
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