This study investigates the effect of {10-12} deformation twins on the continuous precipitation behavior of an extruded Mg-8.0Al-0.5Zn-0.2Mn(AZ80) alloy during aging. The extruded AZ80 alloy is compressed along the tr...This study investigates the effect of {10-12} deformation twins on the continuous precipitation behavior of an extruded Mg-8.0Al-0.5Zn-0.2Mn(AZ80) alloy during aging. The extruded AZ80 alloy is compressed along the transverse direction to introduce {10-12} twins,followed by an aging treatment at 300 ℃. The extruded material exhibits a twin-free microstructure with low internal strain energy, whereas the pre-twinned material possesses abundant {10-12} twins and has high internal strain energy. The aging results reveal that the peak-aging time of the pre-twinned material(1 h) is one-eighth of that of the extruded material(8 h). Although Mg_(17)Al_(12) continuous precipitates(CPs)are observed in both the peak-aged materials, these CPs are much smaller and more densely distributed in the pre-twinned material despite the significantly shorter aging time. The CPs size in the peak-aged materials increases in the following order: twinned region in the pre-twinned material(0.47 μm) < residual matrix region in the pre-twinned material(1.71 μm) < matrix region in the extruded material(2.55 μm).Moreover, the CPs number density in the twinned region of the pre-twinned material is approximately 11 times higher than that in the matrix region of the extruded material. The peak-aged pre-twinned material exhibits significantly higher tensile strength and ductility than the peak-aged extruded material. These results demonstrate that the formation of {10-12} twins in the extruded AZ80 alloy substantially accelerates the static precipitation of CPs during aging at 300 ℃ and improves the tensile properties of the peak-aged material.展开更多
To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexe...To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexes(average temperature,average moisture content,average retention rate of the total anthocyanin content,temperature contrast value,and moisture dispersion value)were investigated via the response surface method(RSM)and the artificial neural network(ANN)with genetic algorithm(GA).The results showed that the microwave intensity and drying time dominated the changes of evaluation indexes.Overall,the ANN model was superior to the RSM model with better estimation ability,and higher drying uniformity and anthocyanin retention rate were achieved for the ANN-GA model compared with RSM.The optimal parameters were microwave intensity of 5.53 W•g^(-1),air velocity of 1.22 m·s^(-1),and drying time of 5.85 min.This study might provide guidance for process optimization of microwave drying berry fruits.展开更多
We previously showed that hydrogen sulfide(H2S)has a neuroprotective effect in the context of hypoxic ischemic brain injury in neonatal mice.However,the precise mechanism underlying the role of H2S in this situation r...We previously showed that hydrogen sulfide(H2S)has a neuroprotective effect in the context of hypoxic ischemic brain injury in neonatal mice.However,the precise mechanism underlying the role of H2S in this situation remains unclear.In this study,we used a neonatal mouse model of hypoxic ischemic brain injury and a lipopolysaccharide-stimulated BV2 cell model and found that treatment with L-cysteine,a H2S precursor,attenuated the cerebral infarction and cerebral atrophy induced by hypoxia and ischemia and increased the expression of miR-9-5p and cystathionineβsynthase(a major H2S synthetase in the brain)in the prefrontal cortex.We also found that an miR-9-5p inhibitor blocked the expression of cystathionineβsynthase in the prefrontal cortex in mice with brain injury caused by hypoxia and ischemia.Furthermore,miR-9-5p overexpression increased cystathionine-β-synthase and H2S expression in the injured prefrontal cortex of mice with hypoxic ischemic brain injury.L-cysteine decreased the expression of CXCL11,an miR-9-5p target gene,in the prefrontal cortex of the mouse model and in lipopolysaccharide-stimulated BV-2 cells and increased the levels of proinflammatory cytokines BNIP3,FSTL1,SOCS2 and SOCS5,while treatment with an miR-9-5p inhibitor reversed these changes.These findings suggest that H2S can reduce neuroinflammation in a neonatal mouse model of hypoxic ischemic brain injury through regulating the miR-9-5p/CXCL11 axis and restoringβ-synthase expression,thereby playing a role in reducing neuroinflammation in hypoxic ischemic brain injury.展开更多
The differential equations of continuum mechanics are the basis of an uncountable variety of phenomena and technological processes in fluid-dynamics and related fields.These equations contain derivatives of the first ...The differential equations of continuum mechanics are the basis of an uncountable variety of phenomena and technological processes in fluid-dynamics and related fields.These equations contain derivatives of the first order with respect to time.The derivation of the equations of continuum mechanics uses the limit transitions of the tendency of the volume increment and the time increment to zero.Derivatives are used to derive the wave equation.The differential wave equation is second order in time.Therefore,increments of volume and increments of time in continuum mechanics should be considered as small but finite quantities for problems of wave formation.This is important for calculating the generation of sound waves and water hammer waves.Therefore,the Euler continuity equation with finite time increments is of interest.The finiteness of the time increment makes it possible to take into account the quadratic and cubic invariants of the strain rate tensor.This is a new branch in hydrodynamics.Quadratic and cubic invariants will be used in differential wave equations of the second and third order in time.展开更多
The predominant method for smart phone accessing is confined to methods directing the authentication by means of Point-of-Entry that heavily depend on physiological biometrics like,fingerprint or face.Implicit continuou...The predominant method for smart phone accessing is confined to methods directing the authentication by means of Point-of-Entry that heavily depend on physiological biometrics like,fingerprint or face.Implicit continuous authentication initiating to be loftier to conventional authentication mechanisms by continuously confirming users’identities on continuing basis and mark the instant at which an illegitimate hacker grasps dominance of the session.However,divergent issues remain unaddressed.This research aims to investigate the power of Deep Reinforcement Learning technique to implicit continuous authentication for mobile devices using a method called,Gaussian Weighted Cauchy Kriging-based Continuous Czekanowski’s(GWCK-CC).First,a Gaussian Weighted Non-local Mean Filter Preprocessing model is applied for reducing the noise pre-sent in the raw input face images.Cauchy Kriging Regression function is employed to reduce the dimensionality.Finally,Continuous Czekanowski’s Clas-sification is utilized for proficient classification between the genuine user and attacker.By this way,the proposed GWCK-CC method achieves accurate authen-tication with minimum error rate and time.Experimental assessment of the pro-posed GWCK-CC method and existing methods are carried out with different factors by using UMDAA-02 Face Dataset.The results confirm that the proposed GWCK-CC method enhances authentication accuracy,by 9%,reduces the authen-tication time,and error rate by 44%,and 43%as compared to the existing methods.展开更多
基金supported by the National Research Foundation of Korea (NRF) (grant no.2019R1A2C1085272) funded by the Ministry of Science,ICTFuture Planning (MSIP,South Korea)。
文摘This study investigates the effect of {10-12} deformation twins on the continuous precipitation behavior of an extruded Mg-8.0Al-0.5Zn-0.2Mn(AZ80) alloy during aging. The extruded AZ80 alloy is compressed along the transverse direction to introduce {10-12} twins,followed by an aging treatment at 300 ℃. The extruded material exhibits a twin-free microstructure with low internal strain energy, whereas the pre-twinned material possesses abundant {10-12} twins and has high internal strain energy. The aging results reveal that the peak-aging time of the pre-twinned material(1 h) is one-eighth of that of the extruded material(8 h). Although Mg_(17)Al_(12) continuous precipitates(CPs)are observed in both the peak-aged materials, these CPs are much smaller and more densely distributed in the pre-twinned material despite the significantly shorter aging time. The CPs size in the peak-aged materials increases in the following order: twinned region in the pre-twinned material(0.47 μm) < residual matrix region in the pre-twinned material(1.71 μm) < matrix region in the extruded material(2.55 μm).Moreover, the CPs number density in the twinned region of the pre-twinned material is approximately 11 times higher than that in the matrix region of the extruded material. The peak-aged pre-twinned material exhibits significantly higher tensile strength and ductility than the peak-aged extruded material. These results demonstrate that the formation of {10-12} twins in the extruded AZ80 alloy substantially accelerates the static precipitation of CPs during aging at 300 ℃ and improves the tensile properties of the peak-aged material.
基金Supported by the National Natural Science Foundation of China(32072352)。
文摘To improve drying uniformity and anthocyanin content of the raspberry puree dried in a continuous microwave dryer,the effects of process parameters(microwave intensity,air velocity,and drying time)on evaluation indexes(average temperature,average moisture content,average retention rate of the total anthocyanin content,temperature contrast value,and moisture dispersion value)were investigated via the response surface method(RSM)and the artificial neural network(ANN)with genetic algorithm(GA).The results showed that the microwave intensity and drying time dominated the changes of evaluation indexes.Overall,the ANN model was superior to the RSM model with better estimation ability,and higher drying uniformity and anthocyanin retention rate were achieved for the ANN-GA model compared with RSM.The optimal parameters were microwave intensity of 5.53 W•g^(-1),air velocity of 1.22 m·s^(-1),and drying time of 5.85 min.This study might provide guidance for process optimization of microwave drying berry fruits.
基金supported by the National Natural Science Foundation of China,Nos.82271327(to ZW),82072535(to ZW),81873768(to ZW),and 82001253(to TL).
文摘We previously showed that hydrogen sulfide(H2S)has a neuroprotective effect in the context of hypoxic ischemic brain injury in neonatal mice.However,the precise mechanism underlying the role of H2S in this situation remains unclear.In this study,we used a neonatal mouse model of hypoxic ischemic brain injury and a lipopolysaccharide-stimulated BV2 cell model and found that treatment with L-cysteine,a H2S precursor,attenuated the cerebral infarction and cerebral atrophy induced by hypoxia and ischemia and increased the expression of miR-9-5p and cystathionineβsynthase(a major H2S synthetase in the brain)in the prefrontal cortex.We also found that an miR-9-5p inhibitor blocked the expression of cystathionineβsynthase in the prefrontal cortex in mice with brain injury caused by hypoxia and ischemia.Furthermore,miR-9-5p overexpression increased cystathionine-β-synthase and H2S expression in the injured prefrontal cortex of mice with hypoxic ischemic brain injury.L-cysteine decreased the expression of CXCL11,an miR-9-5p target gene,in the prefrontal cortex of the mouse model and in lipopolysaccharide-stimulated BV-2 cells and increased the levels of proinflammatory cytokines BNIP3,FSTL1,SOCS2 and SOCS5,while treatment with an miR-9-5p inhibitor reversed these changes.These findings suggest that H2S can reduce neuroinflammation in a neonatal mouse model of hypoxic ischemic brain injury through regulating the miR-9-5p/CXCL11 axis and restoringβ-synthase expression,thereby playing a role in reducing neuroinflammation in hypoxic ischemic brain injury.
文摘The differential equations of continuum mechanics are the basis of an uncountable variety of phenomena and technological processes in fluid-dynamics and related fields.These equations contain derivatives of the first order with respect to time.The derivation of the equations of continuum mechanics uses the limit transitions of the tendency of the volume increment and the time increment to zero.Derivatives are used to derive the wave equation.The differential wave equation is second order in time.Therefore,increments of volume and increments of time in continuum mechanics should be considered as small but finite quantities for problems of wave formation.This is important for calculating the generation of sound waves and water hammer waves.Therefore,the Euler continuity equation with finite time increments is of interest.The finiteness of the time increment makes it possible to take into account the quadratic and cubic invariants of the strain rate tensor.This is a new branch in hydrodynamics.Quadratic and cubic invariants will be used in differential wave equations of the second and third order in time.
文摘The predominant method for smart phone accessing is confined to methods directing the authentication by means of Point-of-Entry that heavily depend on physiological biometrics like,fingerprint or face.Implicit continuous authentication initiating to be loftier to conventional authentication mechanisms by continuously confirming users’identities on continuing basis and mark the instant at which an illegitimate hacker grasps dominance of the session.However,divergent issues remain unaddressed.This research aims to investigate the power of Deep Reinforcement Learning technique to implicit continuous authentication for mobile devices using a method called,Gaussian Weighted Cauchy Kriging-based Continuous Czekanowski’s(GWCK-CC).First,a Gaussian Weighted Non-local Mean Filter Preprocessing model is applied for reducing the noise pre-sent in the raw input face images.Cauchy Kriging Regression function is employed to reduce the dimensionality.Finally,Continuous Czekanowski’s Clas-sification is utilized for proficient classification between the genuine user and attacker.By this way,the proposed GWCK-CC method achieves accurate authen-tication with minimum error rate and time.Experimental assessment of the pro-posed GWCK-CC method and existing methods are carried out with different factors by using UMDAA-02 Face Dataset.The results confirm that the proposed GWCK-CC method enhances authentication accuracy,by 9%,reduces the authen-tication time,and error rate by 44%,and 43%as compared to the existing methods.
