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Interpretation of Female Tragedy Semiotics in the White Deer Plain--Take Tian Xiao’e as a Case
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作者 LIN Yi-qing JIA Hong-wei Thawascha Dechsubha 《Journal of Literature and Art Studies》 2021年第9期620-625,共6页
In the novel White Deer Plain,Chen Zhongshi profoundly narrated the tragic fate of the survival of the image of Chinese women,revealed the social status,inner world and character characteristics of women in Chinese tr... In the novel White Deer Plain,Chen Zhongshi profoundly narrated the tragic fate of the survival of the image of Chinese women,revealed the social status,inner world and character characteristics of women in Chinese traditional culture,and explained the tragic root of the survival of Chinese women from the Chinese cultural level.About the description of the characters,Tian Xiao’e was deeper to touch the depths of human nature affection Aaron and reason of conflict,touched the moral self and human self in a culture of conflict,so that the survival of female tragic signs of the novel has a wider significance and general significance.In this article,the author takes Tian Xiao’e as the example,to analyze this typical characteristic from the angle of the female tragedy semiotics in multi-dimensional interpretation of the characters.It is not only has practical significance for gender ethics construction,also has the vital significance to our mind world and the cultural construction today. 展开更多
关键词 White Deer Plain tian xiao’e female tragedy signs
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The Relationship between Dachuan Baijie Muddymen Dance and“Da Xia”and“Da Wu”
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作者 MA Lei 《Journal of Literature and Art Studies》 2024年第9期765-768,共4页
Dachuan Baijie Muddymen Dance is a kind of dance with local characteristics.From its dance movements and prop usage,it should be related to ancient Ba people’s war dance,as well as to recorded ancient dances such as... Dachuan Baijie Muddymen Dance is a kind of dance with local characteristics.From its dance movements and prop usage,it should be related to ancient Ba people’s war dance,as well as to recorded ancient dances such as“Da Xia”and“Da Wu”. 展开更多
关键词 Muddymen Dance Ba people war dance “Da xia” “Da Wu”
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基于国医大师夏桂成教授天癸新解促围绝经期女性再孕经验总结
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作者 葛盛 《中国中医药现代远程教育》 2025年第1期74-77,共4页
围绝经期女性肾气渐衰,冲任虚衰,天癸渐竭,月经紊乱渐而闭止,生育能力明显衰退。国医大师夏桂成教授认为围绝经期女性诸多病症的发病核心在于心(脑)、肾,他在经验总结中重新解读了天癸的含义,认为天癸中“天”指心(脑)言,“癸”指肾言... 围绝经期女性肾气渐衰,冲任虚衰,天癸渐竭,月经紊乱渐而闭止,生育能力明显衰退。国医大师夏桂成教授认为围绝经期女性诸多病症的发病核心在于心(脑)、肾,他在经验总结中重新解读了天癸的含义,认为天癸中“天”指心(脑)言,“癸”指肾言。其调周法亦从补肾调周到心肾合治,逐步调整为以调心为主。临床常以清心滋肾、宁心安神为基本治法,同时兼顾健脾疏肝。文章以“天癸新解”角度,从围绝经期女性生理变化,结合案例分析探讨,为围绝经期女性缓解临床症状、恢复月经周期、创造生育机会。 展开更多
关键词 天癸新解 卵巢功能衰退 调经助孕 夏桂成
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Experimental study of“Tong Xia”purgative method in ameliorating lung injury in acute necrotizing pancreatitis 被引量:31
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作者 Xia Q Jiang JM +3 位作者 Gong X Chen GY Li L Huang ZW 《World Journal of Gastroenterology》 SCIE CAS CSCD 2000年第1期115-118,共4页
AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.... AIM To investigate the role of tumor necrosisfactor(TNF)in lung injury during acutenecrotizing pancreatitis(ANP),and thetherapeutic effect of'Tong Xia'purgativemethod in minimizing the severity of lung injury.METHODS Fourteen canines were randomlydivided into 3 groups:the'Tong Xia'treatmentgroup(n = 5)using Dachengqitang;salinecontrol group(n = 5),and the sham operationgroup(n = 4).TNF activity in serum and inbronchoalveolar lavage fluid(BALF),the serumendotoxin levels were measured,and theseverity of lung injury evaluated.RESULTS Elevation of TNF activity was moreprominent in BALF than in serum.TNF activity inserum at 6 and 12 hours and in BALI:wassignificantly decreased in the'Tong Xia'treatment group than in the saline control one(q=21.11,q=12.07,q=9.03,respectively,P【0.01)and the lung injury was significantlyalleviated at 12 hours as compared with that inthe saline group,manifested as amelioration otthe lung wet/ dry weight ratio,decrease inprotein concentration and neutrophils count inBALF,and improvement of pulmonaryinflammatory changes.A positive correlationwas demonstrated between serum TNF activity and endotoxin level.CONCLUSION Hypersecretion of TNF is shownto be one of the major causes of lung injuryduring ANP;'Tong Xia'purgative method couldalleviate the degree of lung injury mediated byTNF. 展开更多
关键词 Subject headings pancreatitis/therapy LUNG disease tumor NECROSIS factor Tong xia METHOD
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Multistage Enrichment of the Sawafuqi Uranium Deposit: New Insights into Sandstone-hosted Uranium Deposits in the Intramontane Basins of Tian Shan, China 被引量:3
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作者 LIU Zhangyue PENG Suping +6 位作者 QIN Mingkuan LIU Hongxun HUANG Shaohua HE Zhongbo GUO Qiang XU Qiang SONG Jiye 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第6期2138-2152,共15页
Meso-Cenozoic intracontinental orogenic processes in the Tian Shan orogenic belt have significant effect on the sandstone-hosted uranium deposits in the intramontane basins and those adjacent to the orogen. The Sawafu... Meso-Cenozoic intracontinental orogenic processes in the Tian Shan orogenic belt have significant effect on the sandstone-hosted uranium deposits in the intramontane basins and those adjacent to the orogen. The Sawafuqi uranium deposit, which is located in the South Tian Shan orogenic belt, is investigated to reveal the relationships between uranium mineralization and orogenies. Recent exploration results show that the Sawafuqi uranium deposit has tabular, stratiform, quasi-stratiform, and lens-like orebodies and various geological characteristics different from typical interlayer oxidation zone sandstone-hosted uranium deposits. Systematic studies of ore samples from the Sawafuqi uranium deposit using a variety of techniques, including thin section observation, a-track radiograph, electron microprobe and scanning electron microscope, suggest that uranium mineralization is closely related to pyrite and organic matter. Mineralization-related alterations in the host rocks are mainly silicification and argillation including kaolinite, illite (and illite-smectite mixed layer) and chlorite. Tree stages of mineralization were identified in the Sawafuqi uranium deposit: (i) uranium-bearing detritus and synsedimentary initial pre-enrichment; (ii) interlayer oxidization zone uranium mineralization; and (iii) vein-type uranium mineralization. The synsedimentary uranium pre-enrichment represents an early uranium enrichment in the Sawafuqi uranium deposit, and interlayer oxidation zone uranium mineralization formed the main orebodies, which are superimposed by the vein-type uranium mineralization. Combining the results of this study with previous studies on the Meso-Cenozoic orogenies of South Tian Shan, it is proposed that the synsedimentary uranium pre-enrichment of the Sawafuqi uranium deposit was caused by Triassic Tian Shan uplift, and the interlayer oxidation zone uranium mineralization occurred during the Eocence-Oligocene period, when tectonism was relatively quiet, whereas the vein-type uranium mineralization took place in relation to the strong orogeny of South Tian Shan since Miocene. 展开更多
关键词 South tian Shan intracontinental orogeny Sawafuqi uranium deposit multistage uranium mineralization
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AHDC1基因突变致Xia-Gibbs综合征1例报告并文献复习 被引量:3
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作者 杨书婷 李梅 +2 位作者 贾春颖 冉艳萍 吴霞 《临床儿科杂志》 CAS CSCD 北大核心 2019年第11期847-850,共4页
目的探讨AHDC1基因突变致Xia-Gibbs综合征的临床表现、基因变异特点。方法回顾分析2018年12月接诊的1例AHDC1基因突变致Xia-Gibbs综合征患儿的临床资料,并结合文献分析Xia-Gibbs综合征患儿的临床表现、基因突变特点。结果男性患儿,5岁7... 目的探讨AHDC1基因突变致Xia-Gibbs综合征的临床表现、基因变异特点。方法回顾分析2018年12月接诊的1例AHDC1基因突变致Xia-Gibbs综合征患儿的临床资料,并结合文献分析Xia-Gibbs综合征患儿的临床表现、基因突变特点。结果男性患儿,5岁7月,以全面发育落后、面容特殊,耳位低,拇指内收为主要表现;头颅CT示双侧小脑半球后外方脑外间隙增宽、蛛网膜囊肿。学龄前儿童韦克斯勒氏智能测试提示智商重度低下。全外显子检测发现AHDC1基因新发剪切突变c.3185_c.3186 delCA,导致蛋白编码提前终止(p.T 1062 Sfs*63),确诊为Xia-Gibbs综合征。检索万方数据库,检出中文文献1篇;检索PubMed及Medline,检出英文文献16篇;合并该患儿共35例Xia-Gibbs综合征患儿,其中34例为AHDC1基因新发突变,1例为包含AHDC1基因在内的染色体微缺失所致。结论Xia-Gibbs综合征是由AHDC1基因新发突变所致神经系统疾病,其突变位点及临床表现的特异性目前尚无定论,二者的相关性有待进一步研究。 展开更多
关键词 xia-Gibbs综合征 AHDC1基因突变 全外显子测序 儿童
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LATE CENOZOIC TECTONICS ALONG THE NORTHWESTERN MARGIN OF THE TARIM BASIN: INTERACTIONS BETWEEN THE TARIM BASIN AND THE SOUTHERN TIAN SHAN, WEST CHINA 被引量:1
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作者 Chen Jie 1, Qu Guosheng 1, Shen Jun 2, Edward Sobel 3, Nan Ling 4, Tian Qinjian 5,Yin Jinhui 1 (1 Institute of Geology, China Seismological Bureau, P.O.Box 9803, Beijing 100029,China, E\|mail chenjie@mail.263.net.cn 2.Seismological Bureau of X 《地学前缘》 EI CAS CSCD 2000年第S1期323-325,共3页
The Late Cenozoic fold\|and\|thrust zone along the northwestern margin of the Tarim Basin and the adjacent Tian Shan of Central Asia is an actively deforming part of the India\|Asia collision system. This deformation ... The Late Cenozoic fold\|and\|thrust zone along the northwestern margin of the Tarim Basin and the adjacent Tian Shan of Central Asia is an actively deforming part of the India\|Asia collision system. This deformation zone has two remarkable oppositely vergence arcuate fold\|and\|thrust systems (Kepingtage and Kashi\|Atushi fold\|and\|thrust belts) reaching from east of Keping to west of Kashi. This shape is manifested by structure, topography and seismicity. From north to south, this deformation zone is characterized by four main kinematic elements: (1) a hanging\|wall block (Maidan fault and Tuotegongbaizi\|Muziduke thrust system) that represents the Cenozoic reactivation of a late Paleozoic thrust system; (2) an imbricated thrust stack (Kepingtage\|Tashipeshake thrust system) where slices of Tarim platform sediments are thrust south toward the basin; (3) the Kashi\|Atushi fold\|and\|thrust system where thrusting and folding verge toward the Tian Shan; (4) a foot\|wall block (Tarim craton) that dips gently northwest below the sediment\|filled southern Tian Shan basin and generally has little internal deformation. 展开更多
关键词 Late Cenozoic TECTONICS NORTHWESTERN TARIM BASIN tian Shan folding and THRUSTING shortening rate
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The Major Two-stage Shortening Deformation of the Northern Tibet and Tian Shan Area Since the Latest Oligocene 被引量:1
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作者 LU Haijian LI Haibing LIU Dongliang 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2015年第5期1546-1560,共15页
It seems to be progressively recognized that the stress of the India-Asia convergent front can be transferred rapidly through the southern and central Tibetan lithosphere to the northern Tibet, hence leading to the cr... It seems to be progressively recognized that the stress of the India-Asia convergent front can be transferred rapidly through the southern and central Tibetan lithosphere to the northern Tibet, hence leading to the crustal thickening deformation there during or immediately after the onset of the India-Asia collision(ca.55 Ma).This study focuses on the late Cenozoic deformation and tectonic uplift of the northern Tibet and Tian Shan area.Detailed compilations of a variety of proxy data from sediments and bedrocks suggest that the northern Tibet and Tian Shan area underwent one stage of approximately synchronous widespread contractile deformation since 25–20 Ma, which seemed to decrease at circa 18 Ma as revealed by low-temperature thermochronological data.The latest Oligocene-early Miocene was also significant basin-forming episodes when many intermontane subbasins began to receive syntectonic sedimentation in the northeastern Tibet.Subsequently, the other phase of compressional deformation began to encroach more widely into the northern Tibet and Tian Shan area in episodic steps or continuously from 16–12 Ma to present. 展开更多
关键词 shortening deformation the northern Tibet the tian Shan area the latest Oligocene
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Constraining the crustal structure under the central and western Tian Shan based on teleseismic receiver functions and gravity anomalies 被引量:3
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作者 Yonghua Li Hanhan Tang Lei Shi 《Earthquake Science》 2023年第1期1-14,共14页
The Tian Shan is a vast range that spans several countries in Asia.Understanding its evolutionary history may provide valuable insights into intracontinental orogenic dynamics.In this study,we explored the crustal cha... The Tian Shan is a vast range that spans several countries in Asia.Understanding its evolutionary history may provide valuable insights into intracontinental orogenic dynamics.In this study,we explored the crustal characteristics of the Tian Shan and their relationships to the tectonic evolution of the region.A new H-stacking method that combines the P receiver function and gravity anomalies was used to estimate the thickness and ratio of P-to S-wave velocities(Vp/Vs)for 91 broadband seismic stations in the central and western Tian Shan.Our results revealed significant lateral variations in crustal thickness and Vp/Vs.A—45-km-thick crust and an intermediate-high Vp/Vs(-1.74-1.84)were found in the Kazakh Shield and Tarim Basin,which we interpreted to indicate a mafic crystalline basement and lower crust.The central Tian Shan varied greatly in crustal thickness(40-64 km)and Vp/Vs ratio(1.65-2.00).which may be due to crustal shortening,mafic underplating,and crustal melting.In contrast,we observed a relatively thin crust(42-50 km)with an intermediate Vp/Vs ratio(-1.78)in the western Tian Shan.The differences in the crustal structures between the western and central Tian Shan imply that the Talas-Fergana Fault may be trans-lithospheric. 展开更多
关键词 tian Shan crustal thickness crustal composition receiver function gravity anomaly
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Paleoseismological Study of the Late Quaternary Slip-rate along the South Barkol Basin Fault and Its Tectonic Implications,Eastern Tian Shan,Xinjiang 被引量:1
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作者 WU Fuyao RAN Yongkang +2 位作者 XU Liangxin CAO Jun LI An 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2017年第2期429-442,共14页
The easternmost Tian Shan lies in eastern Xinjiang, Central Asia. The South Barkol basin fault(SBF) in the northern part of the easternmost Tian Shan is a major tectonic structure in this orogenic region. The late Q... The easternmost Tian Shan lies in eastern Xinjiang, Central Asia. The South Barkol basin fault(SBF) in the northern part of the easternmost Tian Shan is a major tectonic structure in this orogenic region. The late Quaternary activity, paleoseismology, and deformation characteristics of the fault provide important clues for understanding the tectonic process of the eastern Tian Shan orogen and implementing seismic mitigation. Through interpretation of high-resolution satellite images, unmanned aerial vehicle measurements, and detailed geological and geomorphic investigations, we suggest that the fault exhibits clear left-lateral slip along its western segment. Paleoseismic trenches dug near Xiongkuer reveal evidence of six large paleoearthquakes. The four latest paleoearthquakes were dated: the oldest event occurred at 4663 BC–3839 BC. Data on the horizontal offsets along the probable 1842 Barkol earthquake coseismic rupture suggest clear multiple relationships between cumulative offsets and possible ~4 m of coseismic left-lateral slip per event. From the cumulative offsets and 14 C sample ages, we suggest an average Holocene left-lateral slip rate of 2.4–2.8 mm/a on the SBF, accounting for ~80% of lateral deformation within the entire eastern Tian Shan fault system. This result is comparable with the shortening rate of 2–4 mm/a in the whole eastern Tian Shan, indicating an equal role of strike-slip tectonics and compressional tectonics in this orogen, and that the SBF may accommodate substantial lateral tectonic deformation. 展开更多
关键词 Eastern tian Shan South Barkol basin fault PALEOSEISMOLOGY left-lateral offset slip rate Eastern margin of Tibetan Plateau Proto-Tethys
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Physico-chemical Characteristics and Environmental Significance of Snow Deposition on Haxilegen Glacier No.51 in Tian Shan,China 被引量:2
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作者 DONG Zhiwen LI Zhongqin +2 位作者 ZHANG Mingjun WANG Feiteng WU Lihua 《Journal of Mountain Science》 SCIE CSCD 2011年第3期484-494,共11页
Snow chemistry on the glaciers of alpine regions is a good indicator of atmospheric environmental change.We examine snow chemistry in three snowpits at different altitudes on the Haxilegen Glacier No.51,in the Kuitun ... Snow chemistry on the glaciers of alpine regions is a good indicator of atmospheric environmental change.We examine snow chemistry in three snowpits at different altitudes on the Haxilegen Glacier No.51,in the Kuitun River source,Tian Shan,China,during July-September 2004 to 2007.We use correlation analysis,factor analysis and sea-salt tracing methods to examine the characteristics and sources of major ions and mineral dust particles in the snow.Results show that mineral dust particles and major ions in the snow pits vary seasonally.During the Asian dust period in springtime,the concentration of mineral dust particles and major ions deposited in snow is high,while the concentration is relatively low during the non-dust period of summer and autumn.This may be caused by dust storm activity in central Asia.The order of major ionic concentrations in the snow packs was determined to be Ca2+ > SO42-> NH4+ > NO3-> Cl-> Na+ > Mg2+ > K+.Ca2+ was the dominant cation;SO42- was the dominant anion.We find,with the exception of NO3-,that the variabilities of ionic concentrations are highly correlated.Results show that the glacier region was significantly affected by dust activity and anthropogenic source.The major ions,especially Na+,originate from dust sources of central Asia and from the Ocean,transported by the westerly winds. 展开更多
关键词 Snow chemistry Mineral dust Environmental significance Haxilegen glacier No. 51 tian Shan
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Apatite U–Pb dating and geochemistry of the Kyrgyz South Tian Shan(Central Asia): Establishing an apatite fingerprint for provenance studies 被引量:1
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作者 Stijn Glorie Samantha March +6 位作者 Angus Nixon Fun Meeuws Gary J.O’Sullivan David M.Chew Christopher L.Kirkland Dmitry Konopelko Johan De Grave 《Geoscience Frontiers》 SCIE CAS CSCD 2020年第6期2003-2015,共13页
This paper presents an apatite U-Pb and geochemistry archive for exposed plutons and metamorphic rocks of the Kyrgyz South Tian Shan(STS)within the Central Asian Orogenic Belt.Apatite U-Pb dates and trace-element geoc... This paper presents an apatite U-Pb and geochemistry archive for exposed plutons and metamorphic rocks of the Kyrgyz South Tian Shan(STS)within the Central Asian Orogenic Belt.Apatite U-Pb dates and trace-element geochemistry are provided for 17 samples from late Carboniferous-early Permian I-type granites in the Terktinsky complex and A-type granites in the Kokshaal Range;early Devonian granites in the Kembel complex;Cryogenian granitoids and tuffs from the Middle Tian Shan and gneisses from the Atbashi metamorphic complex.These samples form a comprehensive selection of igneous and metamorphic rocks within the cores of Mesozoic basement highs that supplied detritus to adjacent basins such as the Tarim,Ferghana and Yarkand-Ferghana Basins.Generally,the granitoid samples preserve primary igneous apatite U-Pb ages that are within uncertainty of previously published zircon U-Pb dates.The apatites from the Atbashi metamorphic complex record anomalous Ordovician dates with large uncertainties that are interpreted as mixing ages between Cryogenian protolith formation and Carboniferous metamorphism.Principal component analysis discriminates apatite samples from the different bedrock terranes in the Kyrgyz STS based on their geochemical fingerprint and categorizes the samples with respect to an extensive apatite geochemical archive.The combined apatite-zircon archive provides a novel framework for provenance studies on the Meso-Cenozoic sedimentary history of the Central Asian Orogenic Belt. 展开更多
关键词 Apatite provenance Central Asian Orogenic Belt tian Shan Tarim Basin Ferghana Basin
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EFI/TIANO下的图形界面新方案NUWA
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作者 王海波 张申生 孙元浩 《微型电脑应用》 2007年第10期1-3,共3页
可扩展固件接口(EFI)在操作系统与平台固件之间定义了一个崭新的接口模型,为运行预启动(pre—boot)应用程序和启动操作系统提供了标准环境。TIANO是Intel对EFI 1.10规范的增强实现,涵盖了从开启电源到启动操作系统的全部过程。目前TIANO... 可扩展固件接口(EFI)在操作系统与平台固件之间定义了一个崭新的接口模型,为运行预启动(pre—boot)应用程序和启动操作系统提供了标准环境。TIANO是Intel对EFI 1.10规范的增强实现,涵盖了从开启电源到启动操作系统的全部过程。目前TIANO Shell下仍然采用类似DOS的控制台界面,缺乏友好的用户界面。本文对此提出了一种突破谊模式、充分体现下一代BIOS优势的图形界面新方案NUWA,实验结果分析表明,NUWA体积小、功能完整、界面友好、可扩展性强,具有很好的应用前景。 展开更多
关键词 可扩展固件接口 tian0 NUWA
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AHDC1基因突变致Xia-Gibbs综合征1例报告并文献复习 被引量:5
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作者 路通 吴冰冰 王艺 《中国循证儿科杂志》 CSCD 北大核心 2018年第3期224-227,共4页
目的探讨AHDC1基因突变致Xia-Gibbs综合征的临床特征及基因变异特点。方法回顾性分析1例AHDC1基因突变致Xia-Gibbs综合征患儿的临床资料和全外显子组测序(WES)结果,并行系统检索和文献复习,收集基因诊断明确的Xia-Gibbs综合征患者,总结... 目的探讨AHDC1基因突变致Xia-Gibbs综合征的临床特征及基因变异特点。方法回顾性分析1例AHDC1基因突变致Xia-Gibbs综合征患儿的临床资料和全外显子组测序(WES)结果,并行系统检索和文献复习,收集基因诊断明确的Xia-Gibbs综合征患者,总结临床表现和基因突变信息。结果男,15月龄,因"发育落后"就诊。就诊时不会说话,不会爬;耳位低,左眼内斜视;双侧肌张力降低。心脏超声示卵圆孔未闭,肾脏B超示双侧肾盂积水;颅脑MRI示脑白质减少,胼胝体薄;脑电图示双侧高幅δ波及θ波,两前部明显。WES发现AHDC1基因新发剪切突变c.750_753del CCTC,导致蛋白编码提前终止(p.T252Afs*7)。文献复习共检索到6篇英文文献,与本文病例合并后共报告15例AHDC1突变患儿,均有发育落后、面部畸形、肌张力低下、上呼吸道梗阻和睡眠障碍,共济失调、癫、孤独症、喂养障碍和视力障碍等也较常见,颅脑影像学胼胝体发育不良常见;已报道13个突变位点,剪切突变最常见。结论 AHDC1基因突变致Xia-Gibbs综合征的主要特点为发育落后、面部畸形、肌张力低下和睡眠障碍等,卵圆孔未闭和肾盂积水的表型是否与AHDC1基因突变相关,有待进一步证实。 展开更多
关键词 xia-Gibbs综合征 AHDC1 全外显子测序 儿童
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Xia-Gibbs综合征临床与遗传学分析 被引量:4
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作者 苏惠红 林彩梅 《中国中西医结合儿科学》 2020年第5期457-462,共6页
目的探讨AHDC1基因突变致Xia-Gibbs综合征(XGS)的临床特征及基因变异特点。方法报告2例AHDC1基因突变致XGS患儿的临床资料和全外显子组测序结果,并对文献复习,收集基因诊断明确的XGS病例,总结临床表型和基因突变特点。结果1例为男性,1... 目的探讨AHDC1基因突变致Xia-Gibbs综合征(XGS)的临床特征及基因变异特点。方法报告2例AHDC1基因突变致XGS患儿的临床资料和全外显子组测序结果,并对文献复习,收集基因诊断明确的XGS病例,总结临床表型和基因突变特点。结果1例为男性,1例为女性,确诊年龄分别为7个月和7岁11个月。2例均有运动语言落后、肌张力减低、颅脑MRI异常、脑电图异常,男性患儿有特殊面容(双眼内斜视、鼻梁低平)、皮肤血管瘤、卵圆孔未闭、全外显子组测序发现AHDC1基因新发无义突变c.4321(exon)C>T(p.Q1441X,163),女性患儿有癫痫、全外显子组测序发现AHDC1基因新发移码突变C.1122dupC(p.Gly375fs)。检索PubMed、万方和中国期刊全文数据库,共检索到AHDC1突变相关文献10篇,其中英文8篇,中文2篇,与本文病例合并后共40例AHDC1突变病例,大多数有全面性发育落后(97.5%)、肌张力低下(87.5%)、特殊面容(77.5%)、睡眠呼吸暂停(42.5%),颅脑影像学胼胝体发育不良常见;基因突变以移码突变(70%)最常见。结论AHDC1基因突变致XGS的主要特点为发育落后、肌张力低下、特殊面容和睡眠呼吸暂停等,根据临床表型进行基因检测可明确诊断。 展开更多
关键词 xia-Gibbs综合征 AHDC1 基因 儿童
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AHDC1基因突变致Xia-Gibbs综合征1例报告并文献复习 被引量:1
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作者 覃莹莹 甘剑光 蔡霞 《反射疗法与康复医学》 2022年第1期165-168,共4页
Xia-Gibbs综合征是由AHDC1基因突变所致神经系统疾病.该文报道1例AHDC1基因突变致Xia-Gibbs综合征患儿,并结合文献分析Xia-Gibbs综合征患儿的临床表现、基因突变特点.患儿女,2岁8个月,以全面发育迟缓、面容特殊、宽额、眼距过宽、上斜... Xia-Gibbs综合征是由AHDC1基因突变所致神经系统疾病.该文报道1例AHDC1基因突变致Xia-Gibbs综合征患儿,并结合文献分析Xia-Gibbs综合征患儿的临床表现、基因突变特点.患儿女,2岁8个月,以全面发育迟缓、面容特殊、宽额、眼距过宽、上斜眼、耳位低、双侧足外翻、膝过伸、双侧肌张力过低为主要表现.头颅MRI提示额叶小、额部脑沟裂增宽、两侧脑室前角饱满、胼胝体薄.GESELL发育诊断量表提示智商重度低下.全外显子检测发现AHDC1基因新发杂合突变c.2136delC(p.V712fs),确诊为Xia-Gibbs综合征.检索数据库,检出中文文献3篇、英文文献21篇,合并该患儿共51例Xia-Gibbs综合征.患者均有发育落后,常见症状为特殊面貌、肌张力低下、共济失调、癫痫、孤独症.基因突变位点与临床表型的关系仍有待进一步研究. 展开更多
关键词 xia-Gibbs综合征 AHDC1基因突变 全外显子测序 康复训练
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Mapping the Late-Holocene Glacial Geomorphology and Glacier Surface Types in the Mt. Harajoriha, Central Tian Shan
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作者 Yanan Li Ping Fu 《International Journal of Geosciences》 2019年第6期669-688,共20页
Alpine glaciers in the central Tian Shan are an important indicator of climate change and also the freshwater tower for the transboundary countries in Central Asia. Knowledge about the glacier dynamics in the late Hol... Alpine glaciers in the central Tian Shan are an important indicator of climate change and also the freshwater tower for the transboundary countries in Central Asia. Knowledge about the glacier dynamics in the late Holocene, such as the Little Ice Age, and surface zones is still limited. In this study, two headwater basins, the Xiata and the Muzart basins, in the Harajoriha Mountain Range in northwestern China were selected to investigate the glacial landforms and glacier surface types using a combination of geomorphological mapping and remote sensing analysis. Several types of glacial landforms including glacial valleys, moraine complexes, moraine ridges, and trimlines were identified and manually digitized based on the 30 m Shuttle Radar Topography Mission (SRTM) digital elevation model, 10 m Sentinel-2 satellite imagery, and high-resolution images from Google Earth. In addition, an effective automated mapping algorithm was applied to the modern glaciers from a Landsat 8 scene using its optical and thermal bands to classify glacier facies, i.e. ice, snow, and slush zone, and supraglacial debris cover. Field trip to the forelands of the Aerqialeteer Glacier in the Xiata basin allowed detailed mapping of the proglacial environment and provided field checks for the mapping with GPS tracks and panoramic photos. Through this fused approach, the mapping results showed a combination of different sets of information connecting the glacier retreat since the late Holocene to contemporary glacier properties. They will be of particular value for future chronological reconstruction of past glacial events and for understanding how surface characteristics play a role in the heterogeneity of glacier responses to climate change. 展开更多
关键词 GLACIAL LANDFORMS GLACIER SURFACE Classification CENTRAL tian Shan China
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Effect of salinity on the growth, and agar yield and composition of Gracilaria tenuistipitata var liui Zhang et Xia
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作者 贺丽虹 吴汪黔生 +1 位作者 沈颂东 王得利 《Marine Science Bulletin》 CAS 2002年第1期76-81,共6页
Gracilaria tenuistipitata varliui Zhang el Xia is cultivated at two different salinities (21, 33) in the laboratory for 4 weeks. The daily growth rate is determined. The total agar yield and fractional agar compositio... Gracilaria tenuistipitata varliui Zhang el Xia is cultivated at two different salinities (21, 33) in the laboratory for 4 weeks. The daily growth rate is determined. The total agar yield and fractional agar composition are analyzed. Results show that algae grow faster in low salinity. The total agar yield is higher under high salinity conditions than under low salinity conditions. Among the eight fractions extracted, the yields of cold water extract and 40% ethanol extract are about the highest In low salinities the yields of autoclaved extract and 60% ethanol extract are higher, while the yield of cold water extract is lower relative to high salinities. 展开更多
关键词 Gracilaria tenuistipitata var liui Zhanget xia SALINITY agar yield agar fraction
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Review: Hu Houxuan, "Xia and the Tu State in the Oracle Inscriptions: A Consideration" Gudai Chengbang Shi Yanjiu (Studies on Ancient City States) Renmin Press, 1989, Pp. 340-353. 被引量:1
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作者 RiZhi 《Journal of Ancient Civilizations》 1995年第0期147-148,共2页
This article verified that the Tu state mentioned in the oracle inscriptions was the Xia people after the Xia Dynasty had been conquered by Tang, the first king of the Shang Dynasty m c.a. 16th century B.C. The state... This article verified that the Tu state mentioned in the oracle inscriptions was the Xia people after the Xia Dynasty had been conquered by Tang, the first king of the Shang Dynasty m c.a. 16th century B.C. The state of Xia, which originated from Yu, was entitled "Xia Hou"; its king was hence called "Xia Hou Di" (Emperor of Xia Hou), e.g."Xia Hou Di Qi". The Xia people, together with the Yin (Shang) people, and the Zhou people, were the so-called "people of San Dai" (Three Dynasties). As mentioned in "Lunyu, Bayi", they founded the states, with the Xia people being associated with the pine, the Yin people with the cypress, and the Zhou people with the chestnut. 展开更多
关键词 A Consideration Renmin Press Studies on Ancient City States xia and the Tu State in the Oracle Inscriptions Hu Houxuan Gudai Chengbang Shi Yanjiu
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蓟县山区波氏栉Xia虎鱼Ctenogobius cliffordpopei...
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作者 李玉和 张新亚 《南开大学学报(自然科学版)》 CAS CSCD 1990年第4期68-74,共7页
关键词 鲈形目 xia虎鱼 波氏栉xia虎鱼
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