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All-optical controlled-NOT logic gate achieving directional asymmetric transmission based on metasurface doublet 被引量:9
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作者 Yijia Huang Tianxiao Xiao +9 位作者 Shuai Chen Zhengwei Xie Jie Zheng Jianqi Zhu Yarong Su Weidong Chen Ke Liu Mingjun Tang Peter Müller-Buschbaum Ling Li 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2023年第7期41-49,共9页
Optical logic gates play important roles in all-optical logic circuits,which lie at the heart of the next-generation optical computing technology.However,the intrinsic contradiction between compactness and robustness ... Optical logic gates play important roles in all-optical logic circuits,which lie at the heart of the next-generation optical computing technology.However,the intrinsic contradiction between compactness and robustness hinders the development in this field.Here,we propose a simple design principle that can possess multiple-input-output states according to the incident circular polarization and direction based on the metasurface doublet,which enables controlled-NOT logic gates in infrared region.Therefore,the directional asymmetric electromagnetic transmission can be achieved.As a proof of concept,a spin-dependent Janus metasurface is designed and experimentally verified that four distinct images corresponding to four input states can be captured in the far-field.In addition,since the design method is derived from geometric optics,it can be easily applied to other spectra.We believe that the proposed metasurface doublet may empower many potential applications in chiral imaging,chiroptical spectroscopy and optical computing. 展开更多
关键词 metasurface polarization control asymmetric transmission logic gate
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Skyrmion-based logic gates controlled by electric currents in synthetic antiferromagnet
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作者 李林霖 罗佳 +3 位作者 夏静 周艳 刘小晰 赵国平 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第1期522-529,共8页
Skyrmions in synthetic antiferromagnetic(SAF) systems have attracted much attention in recent years due to their superior stability, high-speed mobility, and completely compensated skyrmion Hall effect. They are promi... Skyrmions in synthetic antiferromagnetic(SAF) systems have attracted much attention in recent years due to their superior stability, high-speed mobility, and completely compensated skyrmion Hall effect. They are promising building blocks for the next generation of magnetic storage and computing devices with ultra-low energy and ultra-high density.Here, we theoretically investigate the motion of a skyrmion in an SAF bilayer racetrack and find the velocity of a skyrmion can be controlled jointly by the edge effect and the driving force induced by the spin current. Furthermore, we propose a logic gate that can realize different logic functions of logic AND, OR, NOT, NAND, NOR, and XOR gates. Several effects including the spin–orbit torque, the skyrmion Hall effect, skyrmion–skyrmion repulsion, and skyrmion–edge interaction are considered in this design. Our work may provide a way to utilize the SAF skyrmion as a versatile information carrier for future energy-efficient logic gates. 展开更多
关键词 SKYRMIONS logic gates synthetic antiferromagnets micromagnetic simulation
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Thermal spin molecular logic gates modulated by an electric field
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作者 谭兴毅 李强 任达华 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第5期591-595,共5页
Logic gates are fundamental structural components in all modern digital electronic devices. Here, nonequilibrium Green's functions are incorporated with the density functional theory to verify the thermal spin tra... Logic gates are fundamental structural components in all modern digital electronic devices. Here, nonequilibrium Green's functions are incorporated with the density functional theory to verify the thermal spin transport features of the single-molecule spintronic devices constructed by a single molecule in series or parallel connected with graphene nanoribbons electrodes. Our calculations demonstrate that the electric field can manipulate the spin-polarized current. Then, a complete set of thermal spin molecular logic gates are proposed, including AND, OR, and NOT gates. The mentioned logic gates enable different designs of complex thermal spin molecular logic functions and facilitate the electric field control of thermal spin molecular devices. 展开更多
关键词 thermal spin molecular logic gates electric field SINGLE-MOLECULE
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High-performance chiral all-optical OR logic gate based on topological edge states of valley photonic crystal
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作者 王晓蓉 费宏明 +6 位作者 林瀚 武敏 康丽娟 张明达 刘欣 杨毅彪 肖连团 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第7期392-398,共7页
For all-optical communication and information processing,it is necessary to develop all-optical logic gates based on photonic structures that can directly perform logic operations.All-optical logic gates have been dem... For all-optical communication and information processing,it is necessary to develop all-optical logic gates based on photonic structures that can directly perform logic operations.All-optical logic gates have been demonstrated based on conventional waveguides and interferometry,as well as photonic crystal structures.Nonetheless,any defects in those structures will introduce high scattering loss,which compromises the fidelity and contrast ratio of the information process.Based on the spin-valley locking effect that can achieve defect-immune unidirectional transmission of topological edge states in valley photonic crystals(VPCs),we propose a high-performance all-optical logic OR gate based on a VPC structure.By tuning the working bandwidth of the two input channels,we prevent interference between the two channels to achieve a stable and high-fidelity output.The transmittance of both channels is higher than 0.8,and a high contrast ratio of 28.8 dB is achieved.Moreover,the chirality of the logic gate originated from the spin-valley locking effect allows using different circularly polarized light as inputs,representing“1”or“0”,which is highly desired in quantum computing.The device’s footprint is 18μm×12μm,allowing high-density on-chip integration.In addition,this design can be experimentally fabricated using current nanofabrication techniques and will have potential applications in optical communication,information processing,and quantum computing. 展开更多
关键词 topological photonics topological edge state valley photonic crystal all-optical logic gate
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吗啡诱导大鼠镇痛耐受和脊髓GIRK1-2表达减少
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作者 杨翘睿 王晓娥 +1 位作者 崔宇 肖力 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2024年第5期701-708,共8页
【目的】观察G蛋白门控内向整流钾离子通道(GIRK)亚单位GIRK1和GIRK2在吗啡耐受大鼠脊髓背角的表达变化并探讨其调控机制。【方法】成年雄性SD大鼠连续7 d鞘内注射吗啡(15μg/d)建立吗啡耐受模型。在每天吗啡注射前30 min,鞘内注射蛋白... 【目的】观察G蛋白门控内向整流钾离子通道(GIRK)亚单位GIRK1和GIRK2在吗啡耐受大鼠脊髓背角的表达变化并探讨其调控机制。【方法】成年雄性SD大鼠连续7 d鞘内注射吗啡(15μg/d)建立吗啡耐受模型。在每天吗啡注射前30 min,鞘内注射蛋白激酶C-ε(PKCε)选择性抑制剂εV1-2(10μg),观察对吗啡耐受以及脊髓背角GIRK1和GIRK2表达的影响。24只大鼠随机平均分成四组:生理盐水组(saline)、吗啡组(morphine)、吗啡+生理盐水组(morphine+saline)和吗啡+εV1-2组(morphine+εV1-2)。所有大鼠在1 d、3 d、5 d和7 d,药物注射前和吗啡注射后30 min后检测热痛阈值,在第7天行为学测试结束后,免疫荧光检测脊髓背角GIRK1和GIRK2的表达。【结果】荧光双染显示,GIRK1和GIRK2主要分布于大鼠脊髓背角I-Ⅱ板层,且与μ阿片受体(MOR)共染。与生理盐水组相比,连续7 d鞘内注射吗啡导致吗啡镇痛效应显著下降(P<0.001),同时导致脊髓背角GIRK1(22.45±10.58vs.62.83±20.80,P<0.001)和GIRK2(23.67±8.78 vs.50.17±11.05,P=0.001)表达显著降低。荧光双染显示,PKCε与GIRK1和GIRK2在脊髓背角共染。鞘内注射εV1-2可以有效抑制吗啡耐受的形成(P<0.001),且抑制吗啡诱导的GIRK1(54.50±10.37 vs.19.33±9.48,P<0.001)和GIRK2(39.83±6.24 vs.15.83±9.58,P=0.001)表达降低。【结论】脊髓背角GIRK1和GIRK2下调与吗啡耐受密切相关,PKCε是吗啡诱导GIRK1和GIRK2下调的重要原因。 展开更多
关键词 吗啡 耐受 G蛋白门控内向整流钾离子通道亚单位1 G蛋白门控内向整流钾离子通道亚单位2 蛋白激酶C-ε
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CTNNB1、TP53蛋白在儿童肝母细胞瘤组织中的表达及与病理特征、预后的关系
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作者 许彩霞 盛玉 《联勤军事医学》 CAS 2024年第4期304-308,共5页
目的 探讨钙黏蛋白相关蛋白(cadherin associated protein beta 1,CTNNB1)、肿瘤抑制因子P53(tumor suppressor factor P53,TP53)蛋白在儿童肝母细胞瘤(hepatoblastoma, HB)组织中的表达及与病理特征、预后的关系。方法 选取2017-06/202... 目的 探讨钙黏蛋白相关蛋白(cadherin associated protein beta 1,CTNNB1)、肿瘤抑制因子P53(tumor suppressor factor P53,TP53)蛋白在儿童肝母细胞瘤(hepatoblastoma, HB)组织中的表达及与病理特征、预后的关系。方法 选取2017-06/2020-06月作者医院收治的72例HB患儿为研究对象,手术留取癌组织标本及对应的癌旁组织。连续随访3年,记录患儿的预后生存情况,并计算总生存率(overall survival, OS)。采用免疫组织化学法检测CTNNB1、TP53蛋白在HB患儿癌组织及癌旁组织中的表达情况;采用χ~2检验分析CTNNB1、TP53蛋白表达与HB患儿临床病理特征的关系;采用多因素Cox回归分析探讨HB患儿预后的影响因素。结果 HB患儿癌组织中CTNNB1阳性表达率(76.39%)高于对照组(43.06%),TP53阴性表达率(70.83%)高于对照组(38.89%)(P均<0.05)。初诊甲胎蛋白浓度≥100μg/L、POST-TEXT分期Ⅲ~Ⅳ期、肿瘤直径≥3 cm、有肿瘤侵袭或转移HB患儿的CTNNB1阳性表达率、TP53阴性表达率高于初诊甲胎蛋白<100μg/L、POST-TEXT分期Ⅰ~Ⅱ期、肿瘤直径<3 cm、无肿瘤侵袭或转移HB患儿(P均<0.05)。初诊甲胎蛋白≥100μg/L、POST-TEXT分期Ⅲ~Ⅳ期、有肿瘤侵袭或转移、CTNNB1阳性表达、TP53阴性表达的HB患儿3年OS低于初诊甲胎蛋白<100μg/L、POST-TEXT分期Ⅰ~Ⅱ期、无肿瘤侵袭或转移、CTNNB1阴性表达、TP53阳性表达的HB患儿(P均<0.05)。多因素Cox回归分析结果显示,POST-TEXT分期Ⅲ~Ⅳ期(HR=2.077,95%CI:1.423~3.032)、有肿瘤侵袭或转移(HR=2.291,95%CI:1.536~3.417)、CTNNB1阳性表达(HR=2.757,95%CI:1.781~4.268)、TP53阴性表达(HR=2.477,95%CI:1.635~3.753)是HB患儿预后的独立危险因素(P<0.05)。结论 HB患儿癌组织中CTNNB1主要呈阳性表达,而TP53主要呈阴性表达,二者与初诊甲胎蛋白、POST-TEXT分期、肿瘤直径、有肿瘤侵袭或转移密切相关,有望作为评估HB患儿预后的生物学指标。 展开更多
关键词 钙黏蛋白相关蛋白 肿瘤抑制因子P53 儿童 肝母细胞瘤 病理特征 预后
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“1+X”证书制度下职业院校“三教”改革内涵意蕴、逻辑理路与行动策略
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作者 高博 《襄阳职业技术学院学报》 2024年第5期5-10,共6页
随着《国家职业教育改革实施方案》的出台,“三教”改革成为职业教育改革新的热点。基于“1+X”证书制度背景的“三教”改革,旨在解决职业教育类型“教育者、教学内容、教学方法论”的核心问题,意在优化教学模式,落实职业技术类型人才培... 随着《国家职业教育改革实施方案》的出台,“三教”改革成为职业教育改革新的热点。基于“1+X”证书制度背景的“三教”改革,旨在解决职业教育类型“教育者、教学内容、教学方法论”的核心问题,意在优化教学模式,落实职业技术类型人才培养,重在“书证融通”模式构建。职业院校“三教”改革既是一种价值取向,具有教育靶向逻辑;又是一种目标取向,具有教育系统逻辑;还是一种发展尺度,具有教育融合逻辑。应立足产业和教育信息技术前沿,根据院校已有资源及相关产业状况拟定合理化措施,落实“三教”改革,实现产教结合,提升教师整体协同性,重构课证融通新理念,彰显新形态教材的科学性,提升教师教学内生动力,促进教学方法论的多元革新。 展开更多
关键词 1+X”证书制度 “三教”改革 内涵意蕴 逻辑理路
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LncRNA KCNQ1OT1靶向miR-9-5p对口腔癌细胞黏附性及活性的影响
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作者 王敏 庄志征 +4 位作者 周胜男 王旭欣 王静璇 刘红悦 李松 《贵州医科大学学报》 CAS 2024年第7期1011-1017,共7页
目的探究长链非编码RNA钾电压门控通道亚家族Q成员1反向转录物1(LncRNA KCNQ1OT1)靶向miR-9-5p对口腔鳞状细胞癌细胞黏附性及活性的影响。方法体外培养口腔癌SCC25细胞,分别转染LncRNA KCNQ1OT1阴性对照、LncRNA KCNQ1OT1 siRNA、miR-9... 目的探究长链非编码RNA钾电压门控通道亚家族Q成员1反向转录物1(LncRNA KCNQ1OT1)靶向miR-9-5p对口腔鳞状细胞癌细胞黏附性及活性的影响。方法体外培养口腔癌SCC25细胞,分别转染LncRNA KCNQ1OT1阴性对照、LncRNA KCNQ1OT1 siRNA、miR-9-5p阴性对照、miR-9-5p siRNA、LncRNA KCNQ1OT1 siRNA和miR-9-5p siRNA,分别记为KCNQ1OT1-NC组、KCNQ1OT1组、miR-9-5p-NC组、miR-9-5p组,KCNQ1OT1+miR-9-5p组及口腔癌组;采用RT-PCR检测各组细胞的LncRNA KCNQ1OT1及miR-9-5p水平,MTT法检测细胞吸光度(OD)值,流式细胞仪检测细胞凋亡率,Western blot检测细胞中CD44S及CD44V5蛋白表达;通过双荧光素酶报告证实LncRNA KCNQ1OT1与miR-9-5p靶向关系。结果KCNQ1OT1组LncRNA KCNQ1OT1水平低于口腔癌组(P<0.05),miR-9-5p组miR-9-5p水平低于口腔癌组(P<0.05);与口腔癌组相比,KCNQ1OT1组、miR-9-5p组、KCNQ1OT1+miR-9-5p组细胞OD值、CD44S及CD44V5蛋白降低,细胞凋亡率升高(P<0.05),且以KCNQ1OT1+miR-9-5p组效果最为显著(P<0.05);双荧光素酶报告结果显示,miR-9-5p是LncRNA KCNQ1OT1的靶基因。结论LncRNA KCNQ1OT1可通过调控miR-9-5p表达从而降低口腔鳞状细胞癌细胞黏附性,抑制口腔鳞状细胞癌细胞增殖,诱导其凋亡。 展开更多
关键词 口腔肿瘤 长链非编码RNA钾电压门控通道亚家族Q成员1反向转录物1 微小RNA-9-5p 细胞黏附性 细胞活性
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温针灸对兔膝骨关节炎软骨中ASC、Caspase-1和P2X7蛋白表达的影响
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作者 王亭 刘娣 +2 位作者 刘君伟 李龙 武永利 《宁夏医科大学学报》 2024年第4期406-412,共7页
目的 观察温针灸对膝骨关节炎(KOA)模型兔关节软骨组织中凋亡相关斑点样蛋白(ASC)、半胱氨酸蛋白酶-1(Caspase-1)、嘌呤能离子通道型受体7(P2X7)表达的影响,研究温针灸治疗KOA的作用机制。方法 取40只雄性新西兰兔随机分为空白组、模型... 目的 观察温针灸对膝骨关节炎(KOA)模型兔关节软骨组织中凋亡相关斑点样蛋白(ASC)、半胱氨酸蛋白酶-1(Caspase-1)、嘌呤能离子通道型受体7(P2X7)表达的影响,研究温针灸治疗KOA的作用机制。方法 取40只雄性新西兰兔随机分为空白组、模型组、抑制剂组和温针灸组,每组10只。除空白组外,其余各组采用经典右后肢膝关节伸直位,用石膏管型固定4周制备兔KOA模型。造模成功后,各组给予相应干预措施。应用Lequesne MG评分量表评估兔膝关节状态改变与行为学改变,HE染色观察膝关节软骨病理形态学改变,免疫组织化学法和Western blot法检测软骨组织中ASC、Caspase-1、P2X7蛋白的表达,免疫荧光检测Caspase-1蛋白的表达。结果 造模前,各组实验兔Lequesne MG评分差异无统计学意义(P>0.05);造模后,与空白组相比,其余组Lequesne MG评分均上升(P<0.05);干预治疗后,与模型组比较,温针灸组和抑制剂组评分降低(P<0.05)。HE染色显示,空白组软骨表面结构完整,软骨细胞排列均匀;模型组软骨表面粗糙不平,软骨受损明显,软骨细胞形态大小不一,排列紊乱;抑制剂组和温针灸组软骨表面相对光滑、完整,软骨细胞分布较为均匀,软骨层结构相对清晰。与空白组比较,模型组Mankin’s评分升高(P<0.05);与模型组比较,温针灸组和抑制剂组Mankin’s评分降低(P<0.05)。免疫组织化学法、免疫荧光及Western blot检测结果显示,与空白组比较,模型组ASC、Caspase-1、P2X7的表达均升高(P<0.05);与模型组比较,温针灸组和抑制剂组ASC、Caspase-1、P2X7的表达均降低(P<0.05);温针灸组和抑制剂组相比,ASC、Caspase-1、P2X7表达差异均无统计学意义(P均>0.05)。结论 温针灸可减轻兔KOA软骨损伤,其机制可能与ASC、Caspase-1、P2X7表达降低及细胞焦亡抑制有关。 展开更多
关键词 温针灸 膝骨关节炎 凋亡相关斑点样蛋白 半胱氨酸蛋白酶-1 嘌呤能离子通道型受体7
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Theoretical design of single-molecule NOR and XNOR logic gates by using transition metal dibenzotetraaza[14]annulenes
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作者 Zi-Qun Wang Fei Tang +5 位作者 Mi-Mi Dong Ming-Lang Wang Gui-Chao Hu Jian-Cai Leng Chuan-Kui Wang Guang-Ping Zhang 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第6期411-418,共8页
The idea of replacing traditional silicon-based electronic components with the ones assembled by organic molecules to further scale down the electric circuits has been attracting extensive research focuses.Among the m... The idea of replacing traditional silicon-based electronic components with the ones assembled by organic molecules to further scale down the electric circuits has been attracting extensive research focuses.Among the molecularly assembled components,the design of molecular logic gates with simple structure and high Boolean computing speed remains a great challenge.Here,by using the state-of-the-art nonequilibrium Green’s function theory in conjugation with first-principles method,the spin transport properties of single-molecule junctions comprised of two serially connected transition metal dibenzotetraaza[14]annulenes(TM(DBTAA),TM=Fe,Co)sandwiched between two single-walled carbon nanotube electrodes are theoretically investigated.The numerical results show a close dependence of the spin-resolved current-voltage characteristics on spin configurations between the left and right molecular kernels and the kind of TM atom in TM(DBTAA)molecule.By taking advantage of spin degree of freedom of electrons,NOR or XNOR Boolean logic gates can be realized in Fe(DBTAA)and Co(DBTAA)junctions depending on the definitions of input and output signals.This work proposes a new kind of molecular logic gates and hence is helpful for further miniaturization of the electric circuits. 展开更多
关键词 single-molecule junction molecular logic gate spin transport nonequilibrium Green’s function method
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基于ICL7135的试验测试用4-1/2位数字电压表1/2位消隐功能的实现
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作者 牟浩文 全鑫 +1 位作者 秦晓猛 周小东 《环境技术》 2024年第3期132-136,共5页
可靠性和环境试验的性能测试中,常常需要用到以数字电压表为核心的数字化仪表。当设计一个基于ICL7135芯片的4-1/2位数字电压表电路时,需要对数字显示部分进行首位消隐的功能设计,传统的数字电压表电路中利用单片机的程序控制实现消隐,... 可靠性和环境试验的性能测试中,常常需要用到以数字电压表为核心的数字化仪表。当设计一个基于ICL7135芯片的4-1/2位数字电压表电路时,需要对数字显示部分进行首位消隐的功能设计,传统的数字电压表电路中利用单片机的程序控制实现消隐,当设计电路中不采用单片机时,需考虑新的设计实现首位消隐。本文利用电压表电路中CD4511译码芯片的消隐端,结合A/D芯片的输出信号,设计一个复合逻辑门电路,实现对电路的首位正确消隐。经实验验证,复合逻辑门电路的设计思路是可行的,能保证数字电压表电路首1/2位消隐功能的实现。 展开更多
关键词 数字电压表 ICL7135 消隐电路设计 复合逻辑门电路
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SERPINE1影响结肠癌细胞RKO和LoVo的增殖与凋亡
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作者 陈德合 李登玉 +3 位作者 郭刚 王杰 周倩 李洪涛 《联勤军事医学》 CAS 2024年第4期277-284,共8页
目的探究丝氨酸蛋白酶抑制剂1(serine proteinase inhibitor family E member 1,SERPINE1)在结肠癌(colon adenocarcinoma,COAD)中的表达、意义及对COAD细胞增殖与凋亡的影响,了解其在COAD进展中发挥的生物学功能。方法通过Gene Express... 目的探究丝氨酸蛋白酶抑制剂1(serine proteinase inhibitor family E member 1,SERPINE1)在结肠癌(colon adenocarcinoma,COAD)中的表达、意义及对COAD细胞增殖与凋亡的影响,了解其在COAD进展中发挥的生物学功能。方法通过Gene Expression Profilling Interactive Analysis2.0(GEPIA2.0)数据库分析SERPINE1在COAD中的表达与分期及预后关系。收集作者医院5例COAD患者癌组织与对应的正常结肠组织标本,应用Western blot实验验证SERPINE1在COAD中的表达;接着构建SERPINE1过表达与干扰表达的慢病毒载体,进行细胞转染,通过实时荧光定量逆转录聚合酶链反应(real-time reverse transcription quantitative polymerase chain reaction,RT-qPCR)和Western blot对实验细胞筛选并验证过表达和干扰表达的效率;进而通过细胞计数试剂盒(cell counting kit 8,CCK-8)和Hoechst细胞核染色检测细胞增殖与凋亡;最后通过Western blot实验了解其对增殖标志物Ki-67(marker of proliferation Ki-67,MKI67)、Bcl-2关联X蛋白(Bcl-2 associated X protein,Bax)与B细胞淋巴瘤2基因(B cell lymphoma 2,Bcl-2)比值的影响。结果通过GEPIA2.0数据库查找并分析COAD中SERPINE1表达与临床分期和预后关系发现,SERPINE1在COAD中表达水平高于正常结肠组织,SERPINE1的表达水平与临床分期正相关,而与预后生存总生存期负相关(P均<0.05)。CCK-8实验结果表明,oe-RKO组和oe-LoVo组COAD细胞在48h时间点吸光度(optical density,OD)值大于oe-RKO-NC组和oe-LoVo-NC组,sh-RKO-822组和sh-LoVo-822组COAD细胞在48 h时间点OD值小于sh-RKO-NC和sh-LoVo-NC组(P均<0.05)。Hoechst凋亡细胞核染色结果表明,oe-RKO组和oe-LoVo组COAD细胞凋亡数量低于oe-RKO-NC组和oe-LoVo-NC组,sh-RKO-822组和sh-LoVo-822组COAD细胞凋亡数量明显高于sh-RKO-NC组和sh-LoVo-NC组(P均<0.05)。Western blot结果显示,oe-RKO组和oe-LoVo组COAD细胞MKI67蛋白表达明显高于oe-RKO-NC组和oe-LoVo-NC组,Bax/Bcl-2明显低于oe-RKO-NC组和oe-LoVo-NC组;sh-RKO-822组和sh-LoVo-822组COAD细胞MKI67蛋白表达明显低于sh-RKO-NC组和sh-LoVo-NC组,Bax/Bcl-2明显高于sh-RKO-NC组和sh-LoVo-NC组(P均<0.05)。结论SERPINE1在COAD中高表达、与临床分期正相关,而与患者预后负相关;SERPINE1可能通过影响COAD细胞MKI67表达和Bax/Bcl-2促进COAD RKO和LoVo细胞的增殖,抑制其凋亡。 展开更多
关键词 结肠癌 丝氨酸蛋白酶抑制剂1 增殖 凋亡 生物学功能
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Three-Qutrit Topological SWAP Logic Gate for ISK(I=1,S=1,K=1)Spin System
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作者 Ozge Sahin Azmi Gencten 《Journal of Applied Mathematics and Physics》 2017年第12期2320-2325,共6页
Three Zeeman levels of spin-1 electron or nucleus are called as qutrits in quantum computation. Then, ISK (I = 1, S = 1, K = 1) spin system can be represented as three-qutrit states. Quantum circuits and algorithms co... Three Zeeman levels of spin-1 electron or nucleus are called as qutrits in quantum computation. Then, ISK (I = 1, S = 1, K = 1) spin system can be represented as three-qutrit states. Quantum circuits and algorithms consist of quantum logic gates. By using SWAP logic gate, two quantum states are exchanged. Topological quantum computing can be applied in quantum error correction. In this study, first, Yang-Baxter equation is modified for ISK (I = 1, S = 1, K = 1) spin system. Then three-qutrit topological SWAP logic gate is obtained. This SWAP logic gate is applied for three-qutrit states of ISK (I = 1, S = 1, K = 1) spin system. Three-qutrit SWAP logic gate is also applied to the product operators of ISK (I = 1, S = 1, K = 1) spin system. For these two applications, expected exchange results are found. 展开更多
关键词 Qutrits SWAP logic gate Yang-Baxter Equation Product Operators
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基于1DCNN-GRU的启闭机液压系统故障诊断
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作者 刘英杰 董詠依 +1 位作者 刘鹏鹏 葛孟伟 《现代制造技术与装备》 2024年第4期169-173,共5页
由于启闭机液压系统内部结构复杂,故障信号不易采集,使用AMESim软件搭建启闭机液压系统仿真模型,构建6种典型故障数据集。基于这些数据集,提出一维卷积神经网络(1 Dimensional Convolutional Neural Network,1DCNN)与门控循环单元(Gated... 由于启闭机液压系统内部结构复杂,故障信号不易采集,使用AMESim软件搭建启闭机液压系统仿真模型,构建6种典型故障数据集。基于这些数据集,提出一维卷积神经网络(1 Dimensional Convolutional Neural Network,1DCNN)与门控循环单元(Gated Recurrent Unit,GRU)相结合的故障诊断方法,利用1DCNN提取信号数据的空间特征和GRU提取信号数据的时间特征,实现对信号数据空间及时间特征的融合,并对融合特征进行分类识别。 展开更多
关键词 启闭机 液压系统 一维卷积神经网络(1DCNN) 门控循环单元(GRU) 特征融合 故障诊断
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REVERSIBLE LOGIC GATE NETWORK CASCADE BASED ON PERMUTATION GROUP 被引量:1
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作者 管致锦 秦小麟 戴华 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2008年第3期219-223,共5页
The cascade of reversible logic gate network with n inputs and n outputs forms a group isomorphic to the symmetric group S2^n. Characteristics of a number of gates from the set of all generalized Toffoli gates are stu... The cascade of reversible logic gate network with n inputs and n outputs forms a group isomorphic to the symmetric group S2^n. Characteristics of a number of gates from the set of all generalized Toffoli gates are studied. Any permutation Sn is proved to be generated by a n-cycle 9 and a permutation τ= (ij,ik) together. It shows that any neighboring 2-cycle permutation can be generated by at most two NOT gates without ancilla bit. Based on the above theory, a cascade algorithm for reversible logic gate networks is proposed. A reversible example of logic gate network cascade is given to show the correctness of the algorithm. 展开更多
关键词 logic gates cascade connection permutation group
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“1+1+1+N”专业融合体建设的内涵意蕴、逻辑起点与实践样本
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作者 姜汉荣 《职教通讯》 2023年第9期42-48,共7页
专业建设是中国式职业教育现代化生动实践的重要组成部分。“1+1+1+N”专业融合体以中职学校为核心主体,与职教本科、高职院校以及区域企业等利益主体进行多维、深度合作,因而需从人才培养、科研服务、社会服务、文化传承与创新、国际... 专业建设是中国式职业教育现代化生动实践的重要组成部分。“1+1+1+N”专业融合体以中职学校为核心主体,与职教本科、高职院校以及区域企业等利益主体进行多维、深度合作,因而需从人才培养、科研服务、社会服务、文化传承与创新、国际交流与合作等办学功能上理清“1+1+1+N”专业融合体建设的内涵意蕴,并锚定服务面向、问题导向和系统思维等“1+1+1+N”专业融合体建设的逻辑起点,同时围绕延伸教育链、服务产业链、支撑供应链、打造人才链、提升价值链等几个方面,创新实践“1+1+1+N”专业融合体建设与发展,初步为中国式职业教育现代化提供可能的实践样本。 展开更多
关键词 1+1+1+N”专业融合体 内涵意蕴 逻辑起点 实践样本
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Quantum logic gates operation using SQUID qubits in bimodal cavity 被引量:4
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作者 宋克慧 《Chinese Physics B》 SCIE EI CAS CSCD 2006年第2期286-291,共6页
We present a scheme to realize the basic two-qubit logic gates such as the quantum phase gate and SWAP gate using a detuned microwave cavity interacting with three-level superconducting-quantum-interference-device (S... We present a scheme to realize the basic two-qubit logic gates such as the quantum phase gate and SWAP gate using a detuned microwave cavity interacting with three-level superconducting-quantum-interference-device (SQUID) qubit(s), by placing SQUID(s) in a two-mode microwave cavity and using adiabatic passage methods. In this scheme, the two logical states of the qubit are represented by the two lowest levels of the SQUID, and the cavity fields are treated as quantized. Compared with the previous method, the complex procedures of adjusting tile level spacing of the SQUID and applying the resonant microwave pulse to the SQUID to create transformation are not required. Based on superconducting device with relatively long decoherence time and simplified operation procedure, the gates operate at a high speed, which is important in view of decoherence. 展开更多
关键词 superconducting-quantum-interference-device bimodal cavity adiabatic passage quantum logic gate
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Second Quantization Representation of Quantum Logic Gate Transformations 被引量:2
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作者 MA Lei ZHANG Yong-De 《Communications in Theoretical Physics》 SCIE CAS CSCD 2001年第7期119-121,共3页
By using the theory of multimode linear transformation in Fock space, we offer an effective method to study the quantum logic gates based on fermion states. The forms of some basic quantum logic operations are also ob... By using the theory of multimode linear transformation in Fock space, we offer an effective method to study the quantum logic gates based on fermion states. The forms of some basic quantum logic operations are also obtained. 展开更多
关键词 QUANTUM computation QUANTUM logic gate QUANTUM BIT (qubit)
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Controllable all-optical stochastic logic gates and their delay storages based on the cascaded VCSELs with optical-injection 被引量:5
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作者 钟东洲 罗伟 许葛亮 《Chinese Physics B》 SCIE EI CAS CSCD 2016年第9期342-354,共13页
Using the dynamical properties of the polarization bistability that depends on the detuning of the injected light,we propose a novel approach to implement reliable all-optical stochastic logic gates in the cascaded ve... Using the dynamical properties of the polarization bistability that depends on the detuning of the injected light,we propose a novel approach to implement reliable all-optical stochastic logic gates in the cascaded vertical cavity surface emitting lasers(VCSELs) with optical-injection.Here,two logic inputs are encoded in the detuning of the injected light from a tunable CW laser.The logic outputs are decoded from the two orthogonal polarization lights emitted from the optically injected VCSELs.For the same logic inputs,under electro-optic modulation,we perform various digital signal processing(NOT,AND,NAND,XOR,XNOR,OR,NOR) in the all-optical domain by controlling the logic operation of the applied electric field.Also we explore their delay storages by using the mechanism of the generalized chaotic synchronization.To quantify the reliabilities of these logic gates,we further demonstrate their success probabilities. 展开更多
关键词 all-optical stochastic logic gates delay storage polarization bistable success probability
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DESIGN OF TWO-PHASE SINUSOIDAL POWER CLOCK AND CLOCKED TRANSMISSION GATE ADIABATIC LOGIC CIRCUIT 被引量:5
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作者 Wang Pengjun Yu Junjun 《Journal of Electronics(China)》 2007年第2期225-231,共7页
First the research is conducted on the design of the two-phase sinusoidal power clock generator in this paper. Then the design of the new adiabatic logic circuit adopting the two-phase sinusoidal power clocks--Clocked... First the research is conducted on the design of the two-phase sinusoidal power clock generator in this paper. Then the design of the new adiabatic logic circuit adopting the two-phase sinusoidal power clocks--Clocked Transmission Gate Adiabatic Logic (CTGAL) circuit is presented. This circuit makes use of the clocked transmission gates to sample the input signals, then the output loads are charged and discharged in a fully adiabatic manner by using bootstrapped N-Channel Metal Oxide Semiconductor (NMOS) and Complementary Metal Oxide Semiconductor (CMOS) latch structure. Finally, with the parameters of Taiwan Semiconductor Manufacturing Company (TSMC) 0.25um CMOS device, the transient energy consumption of CTGAL, Bootstrap Charge-Recovery Logic (BCRL) and Pass-transistor Adiabatic Logic (PAL) including their clock generators is simulated. The simulation result indicates that CTGAL circuit has the characteristic of remarkably low energy consumption. 展开更多
关键词 Circuit design Two-phase sinusoidal power clock Clock generator Clocked Transmission gate Adiabatic logic (CTGAL) circuit
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