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lncRNA PVT1对急性髓系白血病HL-60细胞增殖、凋亡的影响
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作者 陈珊 安和兵 +2 位作者 王腾飞 宗广帅 周蕾 《河北医药》 CAS 2024年第13期1936-1939,1945,共5页
目的 探讨长链非编码RNA PVT1基因(lncRNA PVT1)对人急性髓系白血病(AML)HL-60细胞增殖、凋亡的影响。方法 选取106例AML患者为试验组,同期健康体检志愿者100例为对照组,采用实时荧光定量聚合酶链反应(RT-qPCR)检测外周血lncRNA PVT1表... 目的 探讨长链非编码RNA PVT1基因(lncRNA PVT1)对人急性髓系白血病(AML)HL-60细胞增殖、凋亡的影响。方法 选取106例AML患者为试验组,同期健康体检志愿者100例为对照组,采用实时荧光定量聚合酶链反应(RT-qPCR)检测外周血lncRNA PVT1表达。以干扰lncRNA PVT1的质粒转染HL-60细胞株(si-lncRNA PVT1组),同时将转染空载体的HL-60细胞设为对照组(si-Control组),另设正常组。RT-qPCR技术检测细胞中lncRNA PVT1的表达;CCK-8检测细胞的增殖率;流式细胞术检测细胞周期和凋亡的变化;Western blot和RT-qPCR技术检测细胞中细胞周期相关蛋白D1(Cyclin D1)、细胞周期依赖性蛋白激酶抑制因子1A(P21)、B淋巴细胞瘤-2(Bcl-2)、Bcl-2相关X蛋白(Bax)、天冬氨酸蛋白水解酶3 (Caspase 3)表达。结果 试验组患者lncRNA PVT1表达水平高于对照组(P<0.05)。干扰lncRNA表达后HL-60细胞中,si-lncRNA PVT1组lncRNA PVT1水平显著低于si-Control组(P<0.05)。si-lncRNA PVT1组细胞增殖率显著低于si-Control组(P<0.05)。敲低lncRNA PVT1后细胞被显著阻滞于G1期,且明显诱导细胞的凋亡(P<0.05)。si-lncRNA PVT1组与si-Control组比较,Cyclin D1、Bcl-2表达降低,P21、Bax、Caspase 3表达升高(P<0.05)。结论 敲低lncRNA PVT1可抑制HL-60细胞的增殖并诱导其凋亡,提示lncRNA PVT1可能作为AML防治的一个分子靶点。 展开更多
关键词 急性白血病 lncRNA pvt1 增殖 凋亡
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滋金补水膏对慢性阻塞性肺疾病模型大鼠的治疗作用及对lncRNAPVT1、miR-30b-5p表达的影响
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作者 付桃利 李小平 +4 位作者 田辉 荣辉 艾萍 王进军 黄雨威 《广州中医药大学学报》 CAS 2024年第2期429-437,共9页
【目的】探讨滋金补水膏对慢性阻塞性肺疾病(COPD)模型大鼠的治疗作用及机制。【方法】将96只大鼠随机分为正常组,模型组,滋金补水膏低、中、高剂量组,盐酸氨溴索组、滋金补水膏高剂量+pcDNA组,滋金补水膏高剂量+pcDNA-人浆细胞瘤转化... 【目的】探讨滋金补水膏对慢性阻塞性肺疾病(COPD)模型大鼠的治疗作用及机制。【方法】将96只大鼠随机分为正常组,模型组,滋金补水膏低、中、高剂量组,盐酸氨溴索组、滋金补水膏高剂量+pcDNA组,滋金补水膏高剂量+pcDNA-人浆细胞瘤转化迁移基因1(PVT1)组,每组12只。除正常组外,其他各组大鼠采用气道滴注脂多糖(LPS)联合烟雾暴露法构建COPD模型。建模成功后,进行给药干预。给药结束后,采用酶联免疫吸附分析(ELISA)检测大鼠血清中白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)水平;流式细胞术检测大鼠外周血中辅助性T细胞17/调节性T细胞(Th17/Treg)水平,苏木素-伊红(HE)染色法观察肺组织病理变化,实时定量聚合酶链反应(qRT-PCR)法检测血清和肺组织中长链非编码RNA(lncRNA)PVT1、miR-30b-5p表达,Western Blot法检测肺组织中维甲酸相关孤核受体γt(RORγt)、叉头框蛋白P3(Foxp3)蛋白表达,双荧光素酶报告基因实验验证lncRNA PVT1与miR-30b-5p的关系。【结果】与正常组比较,模型组肺泡间隔变大,支气管周围有大量炎症细胞浸润,Treg细胞比例、miR-30b-5p表达水平、Foxp3蛋白表达水平降低,IL-6、TNF-α水平,Th17细胞比例、Th17/Treg比值,lncRNA PVT1表达水平,RORγt蛋白表达水平升高(均P<0.05);与模型组比较,滋金补水膏低、中、高剂量组及盐酸氨溴索组大鼠肺组织病理损伤减轻、Treg细胞比例、miR-30b-5p表达水平、Foxp3蛋白表达水平升高,IL-6、TNF-α水平,Th17细胞比例,Th17/Treg比值,lncRNA PVT1表达水平,RORγt蛋白表达水平降低(均P<0.05)。lncRNA PVT1靶向调控miR-30b-5p表达。【结论】滋金补水膏可能通过调节lncRNA PVT1/miR-30b-5p轴促进Th17/Treg细胞平衡来抑制COPD大鼠炎症反应。 展开更多
关键词 滋金补水膏 慢性阻塞性肺疾病 TH17/TREG lncRNA pvt1 miR-30b-5p 大鼠
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急性髓系白血病患者血清LncRNA PVT1、miR-486-5p表达及预后价值
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作者 陈珊 安和兵 +2 位作者 王腾飞 宗广帅 周蕾 《疑难病杂志》 CAS 2024年第8期955-960,共6页
目的探讨急性髓系白血病(AML)患者血清长链非编码RNA PVT1基因(LncRNA PVT1)、微小RNA-486-5p(miR-486-5p)表达水平与疾病病理特征和预后的关系。方法回顾性选取2017年4月—2019年3月河北北方学院附属第二医院血液科就诊的AML患者100例... 目的探讨急性髓系白血病(AML)患者血清长链非编码RNA PVT1基因(LncRNA PVT1)、微小RNA-486-5p(miR-486-5p)表达水平与疾病病理特征和预后的关系。方法回顾性选取2017年4月—2019年3月河北北方学院附属第二医院血液科就诊的AML患者100例为AML组,选取同期健康体检者100例为健康对照组,采用实时荧光定量聚合酶链反应(RT-qPCR)检测血清LncRNA PVT1、miR-486-5p相对表达量;采用Pearson相关法分析AML患者血清LncRNA PVT1与miR-486-5p水平的相关性;Kaplan-Meier法分析AML患者生存曲线;采用Cox回归分析评价影响AML患者预后的危险因素。结果AML组患者LncRNA PVT1水平高于健康对照组,miR-486-5p水平低于健康对照组(t/P=15.403/<0.001、18.305/<0.001)。Pearson相关性分析显示,AML患者LncRNA PVT1与miR-486-5p水平呈负相关(r=-0.261,P<0.01);不同白细胞计数、骨髓原始细胞比率、NCCN危险分层患者LncRNA PVT1、miR-486-5p水平比较差异有统计学意义(LncRNA PVT1:t/P=2.934/0.004,2.901/0.005,10.985/<0.001;miR-486-5p:t/P=2.598/0.012,2.604/0.012,8.593/<0.001)。LncRNA PVT1高水平表达者3年总生存率低于LncRNA PVT1低水平表达者(χ^(2)/P=14.16/<0.001),miR-486-5p高水平表达者3年总生存率高于miR-486-5p低水平表达者(χ^(2)/P=16.82/<0.001)。Cox回归分析显示,LncRNA PVT1高表达、miR-486-5p低表达、NCCN危险分层高是急性髓系白血病患者预后不良的危险因素[RR(95%CI)=1.982(1.148~2.993),1.668(1.085~2.641),1.659(1.068~2.602)]。结论AML患者LncRNA PVT1高表达,miR-486-5p低表达,二者水平与白细胞计数、骨髓原始细胞比率、NCCN危险分层和患者预后有关。 展开更多
关键词 急性髓系白血病 长链非编码RNA pvt1基因 微小RNA-486-5p 病理特征 预后
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异位表达LncRNA PVT1/EIF4A1促进胃癌细胞增殖迁移的作用研究 被引量:1
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作者 黄景鸿 张蕾 +5 位作者 张伟 梁伟华 蒋金芳 郑志红 潘泽民 李冬妹 《石河子大学学报(自然科学版)》 CAS 北大核心 2024年第1期83-90,共8页
目的探索长链非编码RNA人浆细胞瘤转化迁移基因1(plasmacytoma variant translocation 1,PVT1)协同真核翻译起始因子4A1(human eukaryotic translation initiation factor4A1,EIF4A1)促进人胃癌细胞SGC-7901增殖与迁移能力的作用。方法... 目的探索长链非编码RNA人浆细胞瘤转化迁移基因1(plasmacytoma variant translocation 1,PVT1)协同真核翻译起始因子4A1(human eukaryotic translation initiation factor4A1,EIF4A1)促进人胃癌细胞SGC-7901增殖与迁移能力的作用。方法使用Western Blot检测EIF4A1、real time-PCR检测PVT1在胃癌细胞(SGC-7901、NCI-N87、MGC-803、BGC-823)和正常胃黏膜细胞(GES-1)中的表达量。单独或共同过表达胃癌细胞SGC-7901中的PVT1和EIF4A1,EIF4A1的蛋白表达量使用免疫印迹法检测,PVT1的表达水平使用real time-PCR检测,采用划痕实验和Transwell实验检验细胞的迁移能力,采用MTT实验和平板克隆形成法检验细胞的增殖情况,采用免疫印迹法检测E-cadherin,N-cadherin,smad3和TGF-β蛋白表达量。结果以正常胃黏膜细胞作为对照,筛选有统计学差异的PVT1和EIF4A1的本底表达量低的胃癌细胞(P<0.05)。单独或共同过表达胃癌细胞中PVT1和EIF4A1后,共同过表达组平板克隆形成数为492±8.72,单独过表达PVT1组平板克隆形成数为251±1.53,单独过表达EIF4A1组平板克隆形成数为228±1.52,对照组平板克隆形成数为205±2.08。在MTT实验中,共同过表达组OD值高于单独过表达组和对照组。Transwell结果显示共同过表达组迁移细胞数为308±29.10,单独过表达PVT1组迁移细胞数为222±14.42,单独过表达EIF4A1组迁移细胞数为206±10.58,对照组迁移细胞数为169±18.04。划痕实验结果提示共同过表达组伤痕愈合速率高于单独过表达组和对照组。免疫印迹结果说明共同过表达组E-cadherin低于单独过表达组和对照组,共同过表达组N-cadherin、smad3和TGF-β高于单独过表达组和对照组。以上结果均具有统计学差异(P<0.05)。结论过表达PVT1和EIF4A1可以协同促进SGC-7901细胞的增殖能力,并通过改变EMT相关蛋白的表达促进胃癌细胞SGC-7901的迁移能力。 展开更多
关键词 胃癌 pvt1 EIF4A1 细胞增殖 细胞迁移
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聚合物pVT关系状态方程
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作者 华岱 王建 《塑料》 CAS CSCD 北大核心 2024年第3期109-116,共8页
聚合物的比体积(V)随压力(p)和温度(T)的变化过程主要通过聚合物的压力-比体积-温度(pVT)关系状态方程(EOS)进行描述。聚合物pVT关系状态方程可用作计算一定温度和压力条件下,聚合物的比体积,是研究聚合物相态演变及物质掺混分离规律的... 聚合物的比体积(V)随压力(p)和温度(T)的变化过程主要通过聚合物的压力-比体积-温度(pVT)关系状态方程(EOS)进行描述。聚合物pVT关系状态方程可用作计算一定温度和压力条件下,聚合物的比体积,是研究聚合物相态演变及物质掺混分离规律的重要依据,也是高分子物理和聚合物加工模拟计算必不可少的模型之一。采用理论/半理论和经验方法建立了不同类型及特点的聚合物pVT关系状态方程,根据应用的不同需求而存在显著差别。随着高分子领域数字化智能化的发展,研究并建立了具有适用性和高预测精度的聚合物pVT关系状态方程,对新聚合物材料的开发和新型聚合物加工方法的建立具有重要意义。 展开更多
关键词 聚合物pvt关系 状态方程 胞腔模型 晶格流体 微扰理论 经验模型 人工神经网络
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LncRNA PVT1在胃癌中的研究进展
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作者 王丹君 卢雨林 +4 位作者 张蕾 陈国奥 韩笑 潘泽民 李冬妹 《农垦医学》 2024年第2期145-148,172,共5页
长链非编码RNA浆细胞瘤变异易位体1(Long Non-Coding Ribonucleic Acid Plasmacytoma Variant Translocation 1,LncRNA PVT1)是一种在多种肿瘤中异常表达的LncRNA,与肿瘤的发生、侵袭、患者预后等密切相关。近年来,越来越多的研究表明Ln... 长链非编码RNA浆细胞瘤变异易位体1(Long Non-Coding Ribonucleic Acid Plasmacytoma Variant Translocation 1,LncRNA PVT1)是一种在多种肿瘤中异常表达的LncRNA,与肿瘤的发生、侵袭、患者预后等密切相关。近年来,越来越多的研究表明LncRNA PVT1在胃癌中发挥重要作用。本文将聚焦于LncRNA PVT1在胃癌发生发展及治疗过程中的最新研究进展,探讨并展望其在胃癌的发展及治疗中的价值与可能性。 展开更多
关键词 LncRNA pvt1 胃癌 治疗 预后
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PVT系统耦合海水源热泵性能分析
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作者 周义恒 张殿光 +2 位作者 王旭阳 于宗君 马天燕 《能源与节能》 2024年第2期1-7,13,共8页
针对水产养殖中的控温需求,构建了PVT (Photovoltaic Thermal,光伏光热综合利用技术)系统与海水源热泵耦合系统。以128.78 m^(3)不规则八边形养殖水池为需求对象,通过热负荷计算、设备选型、经济性分析和投资回收期考虑,验证了PVT系统... 针对水产养殖中的控温需求,构建了PVT (Photovoltaic Thermal,光伏光热综合利用技术)系统与海水源热泵耦合系统。以128.78 m^(3)不规则八边形养殖水池为需求对象,通过热负荷计算、设备选型、经济性分析和投资回收期考虑,验证了PVT系统与海水源热泵耦合系统的可行性。经济性分析表明,与传统的单一PVT集热系统辅助电加热系统相比较,该耦合系统仅需0.35 a即可实现动态投资回收。这证明了PVT系统与海水源热泵耦合系统在经济方面具有显著优势。不仅如此,还不断创新,提供了可持续性解决方案,经济性显著,也积极影响环境保护,具备较高的推广价值。研究对未来探索PVT系统与海水源热泵耦合应用具有重要的借鉴价值。 展开更多
关键词 pvt系统 海水源热泵 pvt-海水源热泵耦合 经济性分析
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What diameter?What height?Influence of measures of average tree size on area-based allometric volume relationships
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作者 Yilin Wang John A.Kershaw +2 位作者 Mark J.Ducey Yuan Sun James B.McCarter 《Forest Ecosystems》 SCIE CSCD 2024年第1期100-109,共10页
Volume is an important attribute used in many forest management decisions.Data from 83 fixed-area plots located in central New Brunswick,Canada,are used to examine how different measures of stand-level diameter and he... Volume is an important attribute used in many forest management decisions.Data from 83 fixed-area plots located in central New Brunswick,Canada,are used to examine how different measures of stand-level diameter and height influence volume prediction using a stand-level variant of Honer's(1967)volume equation.When density was included in the models(Volume=f(Diameter,Height,Density))choice of diameter measure was more important than choice of height measure.When density was not included(Volume=f(Diameter,Height)),the opposite was true.For models with density included,moment-based estimators of stand diameter and height performed better than all other measures.For models without density,largest tree estimators of stand diameter and height performed better than other measures.The overall best equation used quadratic mean diameter,Lorey's height,and density(root mean square error=5.26 m^3·ha^(-1);1.9%relative error).The best equation without density used mean diameter of the largest trees needed to calculate a stand density index of 400 and the mean height of the tallest 400 trees per ha(root mean square error=32.08 m^(3)·ha^(-1);11.8%relative error).The results of this study have some important implications for height subsampling and LiDAR-derived forest inventory analyses. 展开更多
关键词 Allometric relationships Stand structure Volume estimation Stand-level attributes
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Three anti-inflammatory polysaccharides from Lonicera japonica Thunb.:insights into the structure-function relationships
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作者 Yu Liu Hongjing Dong +5 位作者 Dongxiao Sun-Waterhouse Wenwen Li Bin Zhang Jinqian Yu Zhichang Qiu Zhenjia Zheng 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第4期2197-2207,共11页
This study demonstrates the feasibility of producing three polysaccharides(neutral LJP-1,acidic LJP-2 and acidic LJP-3)with significant in vitro and in vivo anti-inflammatory activities from the flowers of Lonicera ja... This study demonstrates the feasibility of producing three polysaccharides(neutral LJP-1,acidic LJP-2 and acidic LJP-3)with significant in vitro and in vivo anti-inflammatory activities from the flowers of Lonicera japonica.The three polysaccharides differed in chemical composition,molecular weight(Mw)distribution,glycosidic linkage pattern,functional groups and morphology.They exhibited excellent protective effects(in a dose-dependent manner)in lipopolysaccharide-injured RAW264.7 macrophages and Cu SO4-damaged zebrafish via reducing NO production and inhibiting the overexpressions of inflammation-related transcription factors,inflammatory proteins and cytokines in the NF-κB/MAPK signaling pathways.Their antiinflammatory effects varied owing to their different molecular characteristics and chemical compositions.Overall,LJP-2 at 400μg/m L was the most effective.LJP-2 consisted mainly of→5)-α-L-Araf(1→,→4)-α-LGalp A(1→and→2)-α-L-Rhap(1→residues with terminal T-β-D-Glcp.Thus,honeysuckle flowers are good sources of anti-inflammatory polysaccharides,and precise fractionation enables the production of potent antiinflammatory agents for the development of functional foods and healthcare products. 展开更多
关键词 Honeysuckle polysaccharides FRACTIONATION Molecular characteristics Anti-inflammatory properties Structure-function relationship
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Relationship between Kawasaki disease and abdominal pain
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作者 Yan Pan Fu-Yong Jiao 《World Journal of Clinical Cases》 SCIE 2024年第17期2932-2934,共3页
This editorial presents an analysis of an article recently published in the World Journal of Clinical Cases.Kawasaki disease(KD)is a well-known pediatric vasculitis characterized by fever,rash,conjunctivitis,oral muco... This editorial presents an analysis of an article recently published in the World Journal of Clinical Cases.Kawasaki disease(KD)is a well-known pediatric vasculitis characterized by fever,rash,conjunctivitis,oral mucosal changes,and swelling of the extremities.This editorial aims to delve into the intricate relationship between KD and abdominal pain,drawing insights from recent research findings to provide a comprehensive understanding and potential avenues for future investigation. 展开更多
关键词 Kawasaki disease Abdominal pain relationship RESEARCH INVESTIGATION
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Monitor and Acceptance among Couples in Romantic Relationships:Actor-Partner Interdependence Models Based on the Monitor and Acceptance Theory
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作者 Xue Wen Yuyang Zhou +2 位作者 Jiaxuan Du Xiaoyan Liu Wei Xu 《International Journal of Mental Health Promotion》 2024年第7期589-598,共10页
Communication could be an essential part of couples in their daily life.Based on Monitor and Acceptance Theory(MAT),the present study explored the mediating role of communication in the relationship between mindfulnes... Communication could be an essential part of couples in their daily life.Based on Monitor and Acceptance Theory(MAT),the present study explored the mediating role of communication in the relationship between mindfulness and relationship quality among college-student couples.The research examined the dynamic relationship of monitoring and acceptance to relationship satisfaction in the Actor-Partner Interdependence Model(APIM),and the mediating effect of positive or negative communications in these relationships.A total of 96 pairs of couples in the universities in Nanjing,China participated in the research.Momentary measurements were used to measure the momentary levels of their monitor,acceptance,positive/negative communication,and relationship satisfaction.A Hierarchical Linear Model(HLM)was used to deal with the APIM.Results showed that the women’s monitor facet of state mindfulness negatively predicted men’s relationship satisfaction through women’s negative communication,and the women’s acceptance facet of state mindfulness positively predicted women’s relationship satisfaction through women’s positive and negative communication at the within-person level.The study highlights the importance of cooperation in monitoring and acceptance for couples to own and hold high levels of relationship satisfaction. 展开更多
关键词 Romantic relationship communication MINDFULNESS MONITOR ACCEPTANCE
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Elucidating the structure-activity relationship of Cu-Ag bimetallic catalysts for electrochemical CO_(2) reduction
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作者 Qining Huang Lili Wan +1 位作者 Qingxuan Ren Jingshan Luo 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第6期345-351,I0009,共8页
Developing bimetallic catalysts is an effective strategy for enhancing the activity and selectivity of electrochemical CO_(2) reduction reactions,where understanding the structure-activity relationship is essential fo... Developing bimetallic catalysts is an effective strategy for enhancing the activity and selectivity of electrochemical CO_(2) reduction reactions,where understanding the structure-activity relationship is essential for catalyst design.Herein,we prepared two Cu-Ag bimetallic catalysts with Ag nanoparticles attached to the top or the bottom of Cu nanowires.When tested in a flow cell,the Cu-Ag catalyst with Ag nanoparticles on the bottom achieved a faradaic efficiency of 54%for ethylene production,much higher than the catalyst with Ag nanoparticles on the top.The catalysts were further studied in the H-cell and zero-gap MEA cell.It was found that placing the two metals in the intensified reaction zone is crucial to triggering the tandem reaction of bimetallic catalysts.Our work elucidates the structure-activity relationship of bimetallic catalysts for CO_(2) reduction and demonstrates the importance of considering both catalyst structures and cell characteristics to achieve high activity and selectivity. 展开更多
关键词 Electrochemical CO_(2)reduction Bimetallic catalyst CU-AG Structure-activity relationship
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Floristic composition and edaphic relationships in ferruginous campo rupestre reference ecosystems
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作者 G.Wilson FERNANDES Letícia RAMOS +3 位作者 Dario C.PAIVA Jéssica CUNHA-BLUM Vanessa Matos GOMES Daniel NEGREIROS 《Journal of Mountain Science》 SCIE CSCD 2024年第3期719-733,共15页
Land use change and occupation have led to modifications in the environment causing loss of biodiversity and ecosystem services throughout the planet.Some environments with high economic relevance,such as the ferrugin... Land use change and occupation have led to modifications in the environment causing loss of biodiversity and ecosystem services throughout the planet.Some environments with high economic relevance,such as the ferruginous campo rupestre(rupestrian grassland known as Canga in Brazil),are even more susceptible to severe impacts due to their extreme habitat conditions and low resilience.The determination of reference ecosystems based on the intrinsic characteristics of the ecosystem is essential for conservation as well as to the implementation of ecological restoration.We proposed the reference ecosystem of the three main types of habitats of the ferruginous campo rupestre based on their floristic composition.We described the floristic composition of each habitat and evaluated the physicochemical properties of the soils and the relationship between plants and soils.All three habitats showed high diversity of plant species and many endemic species,such as Chamaecrista choriophylla,Cuphea pseudovaccinium,Lychnophora pinaster,and Vellozia subalata.The distribution of vegetation was strongly related with the edaphic characteristics,with a set of species more adapted to high concentration of base saturation,fine sand,organic carbon,and iron,while another set of species succeeded in more acidic soils with higher S and silt concentration.We provide support for the contention that the ferruginous campo rupestre is a mosaic of different habitats shaped by intrinsic local conditions.Failure to recognize the floristic composition of each particular habitat can lead to inappropriate restoration,increased habitat homogenization and increased loss of biodiversity and ecosystem services.This study also advances the knowledge base for building the reference ecosystem for the different types of ferruginous campo rupestre habitats,as well as a key database for highlighting those species contribute most to community assembly in this diverse and threatened tropical mountain ecosystem. 展开更多
关键词 Canga Ecological restoration Extreme ecosystem Non-forest ecosystems Rupestrian grassland Taxon environment relationships
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The Relationship between Father-Love Absence and Loneliness:Based on the Perspective of the Social Functionalist Theory and the Social Needs Theory
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作者 Yaping Zhou He Zhong +1 位作者 Xiaojun Li Yanhui Xiang 《International Journal of Mental Health Promotion》 2024年第2期139-148,共10页
Fathers play an important role in adolescents’development,which is significant for their development and influences their mental health,including feeling of loneliness.However,the effects and mechanisms of father-lov... Fathers play an important role in adolescents’development,which is significant for their development and influences their mental health,including feeling of loneliness.However,the effects and mechanisms of father-love absence on individual loneliness are not clear.Based on the social functionalist theory and the social needs theory,this study examines the influence of individual fatherlove absence on loneliness and its underlying mechanisms.A questionnaire survey was administered to 319 junior high school students and 1,476 high school students.The results showed that adolescents with father-love absence had higher levels of loneliness,and that father-love absence affected loneliness levels through mediating pathways of individual gratitude,peer relationships,and gratitude to peer relationships.This study not only confirms the negative effects of father-love absence on adolescents’loneliness,but also explains the mediate roles of individual gratitude and peer relationships.It enriches the theoretical system related to family education and has important theoretical and practical implications for further interventions on adolescents’mental health from the perspective of fatherless parenting. 展开更多
关键词 Father-love absence LONELINESS GRATITUDE peer relationships
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Different mechanisms underlie similar species-area relationships in two tropical archipelagoes
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作者 Shengchun Li Tieyao Tu +5 位作者 Shaopeng Li Xian Yang Yong Zheng Liang-Dong Guo Dianxiang Zhang Lin Jiang 《Plant Diversity》 SCIE CAS CSCD 2024年第2期238-246,共9页
Despite much research in the field of island biogeography,mechanisms regulating insular diversity remain elusive.Here,we aim to explore mechanisms underlying plant species-area relationships in two tropical archipelag... Despite much research in the field of island biogeography,mechanisms regulating insular diversity remain elusive.Here,we aim to explore mechanisms underlying plant species-area relationships in two tropical archipelagoes in the South China Sea.We found positive plant species-area relationships for both coral and continental archipelagoes.However,our results showed that different mechanisms contributed to similar plant species-area relationships between the two archipelagoes.For coral islands,soil nutrients and spatial distance among communities played major roles in shaping plant community structure and species diversity.By contrast,the direct effect of island area,and to a lesser extent,soil nutrients determined plant species richness on continental islands.Intriguingly,increasing soil nutrients availability(N,P,K)had opposite effects on plant diversity between the two archipelagoes.In summary,the habitat quality effect and dispersal limitation are important for regulating plant diversity on coral islands,whereas the passive sampling effect,and to a lesser extent,the habitat quality effect are important for regulating plant diversity on continental islands.More generally,our findings indicate that island plant species-area relationships are outcomes of the interplay of both niche and neutral processes,but the driving mechanisms behind these relationships depends on the type of islands. 展开更多
关键词 Coral and continental islands Plant diversity Soil nutrients Species-area relationships The sampling effect
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Modern pollen-vegetation relationships along altitudinal vegetation belts in the Leigong Mountain of southwestern China
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作者 LI Shuming ZHAO Wenwei +7 位作者 WEI Lisi REN Weihe GU Qinran WU Siqi JI Yang YANG Ziteng ZHUANG Rui CHEN Chunzhu 《Journal of Mountain Science》 SCIE CSCD 2024年第7期2249-2262,共14页
Understanding the distribution,dispersal,and correlation of modern pollen with vegetation in mountainous regions is essential for establishing accurate modern analogs for fossil pollen records.This study,conducted in ... Understanding the distribution,dispersal,and correlation of modern pollen with vegetation in mountainous regions is essential for establishing accurate modern analogs for fossil pollen records.This study,conducted in Leigong Mountain on the YunnanGuizhou Plateau of southwestern China,involved the collection of 35 surface soil samples from diverse vegetation communities along an elevational gradient ranging from 1210 to 1875 meters.The results reveal a close correspondence between modern pollen assemblages and vegetation zones.Principal Component Analysis(PCA)results indicate that pollen assemblages can effectively distinguish between subtropical montane evergreen broad-leaved forest(SEBF)and subtropical montane deciduous broadleaved forest(SDBF).However,both SEBF and SDBF show significant overlap with subtropical montane evergreen-deciduous broad-leaved mixed forest(SEMF).Detrended Correspondence Analysis(DCA)results clearly distinguish the three vegetation zones,and the first axis of DCA shows a significant positive correlation with elevation(p<0.01,R=0.48).Discriminant Analysis(DA)successfully assigns 94.4%of the modern pollen samples to their respective vegetation zones.Pollen taxa such as Impatiens,Astertype,and Rosaceae exhibit significant indicative capabilities for the SEBF zone,effectively distinguishing this vegetation zone from others.Pinus and Alnus display overrepresentation in the Leigong Mountain region,while Quercus(D,deciduous-type)and Poaceae exhibit high representation in the SEBF zone.In the SEBF zone,both pollen diversity and richness are the lowest.Our study reveals the complex relationship between the richness and diversity of pollen and vegetation.The diversity and richness of tree and shrub pollen are found to be lower than those of the corresponding plants.The pollen-vegetation relationship elucidated in this study serves as a critical reference for reconstructing ancient environments from fossil pollen retrieved in this region. 展开更多
关键词 Modern pollen assemblages Pollenvegetation relationship Pollen diversity and richness Leigong Mountain Southwestern China
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Predicting Users’ Latent Suicidal Risk in Social Media: An Ensemble Model Based on Social Network Relationships
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作者 Xiuyang Meng Chunling Wang +3 位作者 Jingran Yang Mairui Li Yue Zhang Luo Wang 《Computers, Materials & Continua》 SCIE EI 2024年第6期4259-4281,共23页
Suicide has become a critical concern,necessitating the development of effective preventative strategies.Social media platforms offer a valuable resource for identifying signs of suicidal ideation.Despite progress in ... Suicide has become a critical concern,necessitating the development of effective preventative strategies.Social media platforms offer a valuable resource for identifying signs of suicidal ideation.Despite progress in detecting suicidal ideation on social media,accurately identifying individuals who express suicidal thoughts less openly or infrequently poses a significant challenge.To tackle this,we have developed a dataset focused on Chinese suicide narratives from Weibo’s Tree Hole feature and introduced an ensemble model named Text Convolutional Neural Network based on Social Network relationships(TCNN-SN).This model enhances predictive performance by leveraging social network relationship features and applying correction factors within a weighted linear fusion framework.It is specifically designed to identify key individuals who can help uncover hidden suicidal users and clusters.Our model,assessed using the bespoke dataset and benchmarked against alternative classification approaches,demonstrates superior accuracy,F1-score and AUC metrics,achieving 88.57%,88.75%and 94.25%,respectively,outperforming traditional TextCNN models by 12.18%,10.84%and 10.85%.We assert that our methodology offers a significant advancement in the predictive identification of individuals at risk,thereby contributing to the prevention and reduction of suicide incidences. 展开更多
关键词 Suicide risk prediction social media social network relationships Weibo Tree Hole deep learning
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Relationship between Inter Canine Width and Inter Alar Width, Inter Commissural Width, and Inter Canthal Distance: A Pilot Study
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作者 Grevisse Bindele Ndombolo Augustin Mantshumba Milolo +5 位作者 Fidele Nyimi Bushabu Em Kalala Kazadi Pierrot Kumpanya Ntumba Jean Marie Kayembe Bukama Elias Lubadi Tshilumba Jean Paul Sekele Isouradi 《Open Journal of Stomatology》 2024年第6期279-290,共12页
The aim of this study was to determine the relationship between inter canine width (ICW) and inter alar width (IAW), inter commissural width (ICoW), and inter canthal distance (ICaD) in Bantu population. Materials and... The aim of this study was to determine the relationship between inter canine width (ICW) and inter alar width (IAW), inter commissural width (ICoW), and inter canthal distance (ICaD) in Bantu population. Materials and Methods: It was a pilot study included all participants who were aged at least 18 years, without a history of orthodontics treatment from Prosthodontics Department, Faculty of Dental Medicine, University of Kinshasa. The Ethics committee of the National Center of Research for Dental Sciences in DR Congo approved the study protocol (CNRSB 1504.218). The participants medical records were obtained from the interview and dental examination. Nature of the study was explained with participant information sheet, and an informed consent of all participants was obtained. The inclusion criteria were no missing maxillary and mandibular teeth, no diastema, and no anterior restorations, 18 years old before enrollment in the study. The exclusion criteria were inability to meet the above requirements, pregnancy, and refusal to participate in the study. The inter-canine width (ICW), inter alar width (IAW), inter canthal distance (ICaD) and inter-commissural width (ICoW) of each participant were measured with a digital Vernier caliper (Mitutoyo, UK Ltd.,) (0.01 mm) three times and the average value was recorded. The inter canthal distance (ICaD) was measured without applying pressure by bringing the recording parts of the caliper just in contact with the medial angle. The inter alar width (IAW) was marked with a fine marked pencil on the widest outer surface of the alae of the nose on either side or width. Those two points were measured without applying pressure by bringing the recording parts of the caliper just in contact with the outer surface. The participant was told to stop breathing shortly to avoid any change in shape of the nose. The inter-commissural width (ICoW) was determined by measuring the maxillary lip vermilion from commissure to commissure without the application of pressure on the tissue in the relaxed state. The inter-canine width (ICW) was measured indirectly using a dental floss. A dental floss was marked on one end prior to placement in the mouth. Using that point as reference, the dental floss was circumference along the curvature of the anterior dentition such that it passed along the contact point of all the teeth. The distal end of the canine teeth on both sides was then marked on the floss while it was stretched in the patients mouth. Floss was marked on both sides with the marker pencil. The distance between the two proximal contact points was measured and recorded. Data, analysis and validation were performed by the SPSS software (version 22.0, IBM SPSS Statistics, Chicago, IL, USA). Unpaired t-test was used, of Kolmogorov-Smirnov test. Analysis of variance (ANOVA) test was used to test for comparability between socio-demographic characteristics dental measurements. Pearsons correlation coefficients test was calculated to determine the relationship between facial and dental parameters. Significance was set at P 0.01. Results: Of 314 participants enrolled, 202 were included. The age ranged from 18 to 68 years, with a mean age of 40.62 12.99 years. Although the Pearsons correlation coefficients were negative. Ninety-three participants (46%) were men and one hundred and nine (54%) were women. The overall mean age was 40.62 12.99 years. Facial and dental measurements were greater in women than men with significant differences for ICW (p = 0.04). However, no significant difference was seen between men and women for IAW, ICaD and ICoW (p = 0.44, p = 0.23, p = 0.31 respectively). The correlation including Pearsons correlation coefficient and P-values for all participants is not demonstrated. Conclusion: Within the limitations of this study, the results suggest that IAW, ICaD and ICoW cannot be used as a preliminary method for determining the width of the maxillary for anterior teeth for edentulous patients. 展开更多
关键词 relationship Inter-Canine Width Inter Alar Width Inter Canthal Distance Inter Commissural Width
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A Large-Scale Group Decision Making Model Based on Trust Relationship and Social Network Updating
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作者 Rongrong Ren Luyang Su +2 位作者 Xinyu Meng Jianfang Wang Meng Zhao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第1期429-458,共30页
With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that consid... With the development of big data and social computing,large-scale group decisionmaking(LGDM)is nowmerging with social networks.Using social network analysis(SNA),this study proposes an LGDM consensus model that considers the trust relationship among decisionmakers(DMs).In the process of consensusmeasurement:the social network is constructed according to the social relationship among DMs,and the Louvain method is introduced to classify social networks to form subgroups.In this study,the weights of each decision maker and each subgroup are computed by comprehensive network weights and trust weights.In the process of consensus improvement:A feedback mechanism with four identification and two direction rules is designed to guide the consensus of the improvement process.Based on the trust relationship among DMs,the preferences are modified,and the corresponding social network is updated to accelerate the consensus.Compared with the previous research,the proposedmodel not only allows the subgroups to be reconstructed and updated during the adjustment process,but also improves the accuracy of the adjustment by the feedbackmechanism.Finally,an example analysis is conducted to verify the effectiveness and flexibility of the proposed method.Moreover,compared with previous studies,the superiority of the proposed method in solving the LGDM problem is highlighted. 展开更多
关键词 Large-scale group decision making social network updating trust relationship group consensus feedback mechanism
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PVT光伏光热技术研究现状及展望
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作者 旷文琦 王保忠 +1 位作者 刘洋 刘群波 《区域供热》 2024年第2期17-28,共12页
对PVT光伏光热技术的研究现状进行调研和整理,结果表明:相比于普通光伏系统,PVT系统的综合效率有10%~16%的提升;通过经济性分析,应用PVT技术的采暖、热水方案在5~10年能收回初投资。
关键词 pvt 传热强化 经济性分析 系统性能优化
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