The encapsulation of lunar samples is a core research area in the third phase of the Chinese Lunar Exploration Program.The seal assembly,opening and closing mechanism(OCM),and locking mechanism are the core components...The encapsulation of lunar samples is a core research area in the third phase of the Chinese Lunar Exploration Program.The seal assembly,opening and closing mechanism(OCM),and locking mechanism are the core components of the encapsulation device of the lunar samples,and the requirements of a tight seal,lightweight,and low power make the design of these core components difficult.In this study,a combined sealing assembly,OCM,and locking mechanism were investigated for the device.The sealing architecture consists of rubber and an Ag-In alloy,and a theory was built to analyze the seal.Experiments of the electroplate Au coating on the knife-edge revealed that the hermetic seal can be significantly improved.The driving principle for coaxial double-helical pairs was investigated and used to design the OCM.Moreover,a locking mechanism was created using an electric initiating explosive device with orifice damping.By optimizing the design,the output parameters were adjusted to meet the requirements of the lunar explorer.The experimental results showed that the helium leak rate of the test pieces were not more than 5×10^(-11) Pa·m^(3)·s^(-1),the minimum power of the OCM was 0.3 W,and the total weight of the principle prototype was 2.9 kg.The explosive driven locking mechanism has low impact.This investigation solved the difficulties in achieving tight seal,light weight,and low power for the lunar explorer,and the results can also be used to explore other extraterrestrial objects in the future.展开更多
Objective To evaluate the diagnostic value of histopathological examination of ultrasound-guided puncture biopsy samples in extrapulmonary tuberculosis(EPTB).Methods This study was conducted at the Shanghai Public Hea...Objective To evaluate the diagnostic value of histopathological examination of ultrasound-guided puncture biopsy samples in extrapulmonary tuberculosis(EPTB).Methods This study was conducted at the Shanghai Public Health Clinical Center.A total of 115patients underwent ultrasound-guided puncture biopsy,followed by MGIT 960 culture(culture),smear,Gene Xpert MTB/RIF(Xpert),and histopathological examination.These assays were performed to evaluate their effectiveness in diagnosing EPTB in comparison to two different diagnostic criteria:liquid culture and composite reference standard(CRS).Results When CRS was used as the reference standard,the sensitivity and specificity of culture,smear,Xpert,and histopathological examination were(44.83%,89.29%),(51.72%,89.29%),(70.11%,96.43%),and(85.06%,82.14%),respectively.Based on liquid culture tests,the sensitivity and specificity of smear,Xpert,and pathological examination were(66.67%,72.60%),(83.33%,63.01%),and(92.86%,45.21%),respectively.Histopathological examination showed the highest sensitivity but lowest specificity.Further,we found that the combination of Xpert and histopathological examination showed a sensitivity of 90.80%and a specificity of 89.29%.Conclusion Ultrasound-guided puncture sampling is safe and effective for the diagnosis of EPTB.Compared with culture,smear,and Xpert,histopathological examination showed higher sensitivity but lower specificity.The combination of histopathology with Xpert showed the best performance characteristics.展开更多
Perovskite solar cells(PsCs)have developed tremendously over the past decade.However,the key factors influencing the power conversion efficiency(PCE)of PSCs remain incompletely understood,due to the complexity and cou...Perovskite solar cells(PsCs)have developed tremendously over the past decade.However,the key factors influencing the power conversion efficiency(PCE)of PSCs remain incompletely understood,due to the complexity and coupling of these structural and compositional parameters.In this research,we demon-strate an effective approach to optimize PSCs performance via machine learning(ML).To address chal-lenges posed by limited samples,we propose a feature mask(FM)method,which augments training samples through feature transformation rather than synthetic data.Using this approach,squeeze-and-excitation residual network(SEResNet)model achieves an accuracy with a root-mean-square-error(RMSE)of 0.833%and a Pearson's correlation coefficient(r)of 0.980.Furthermore,we employ the permu-tation importance(PI)algorithm to investigate key features for PCE.Subsequently,we predict PCE through high-throughput screenings,in which we study the relationship between PCE and chemical com-positions.After that,we conduct experiments to validate the consistency between predicted results by ML and experimental results.In this work,ML demonstrates the capability to predict device performance,extract key parameters from complex systems,and accelerate the transition from laboratory findings to commercialapplications.展开更多
Accurate and reliable fault detection is essential for the safe operation of electric vehicles.Support vector data description(SVDD)has been widely used in the field of fault detection.However,constructing the hypersp...Accurate and reliable fault detection is essential for the safe operation of electric vehicles.Support vector data description(SVDD)has been widely used in the field of fault detection.However,constructing the hypersphere boundary only describes the distribution of unlabeled samples,while the distribution of faulty samples cannot be effectively described and easilymisses detecting faulty data due to the imbalance of sample distribution.Meanwhile,selecting parameters is critical to the detection performance,and empirical parameterization is generally timeconsuming and laborious and may not result in finding the optimal parameters.Therefore,this paper proposes a semi-supervised data-driven method based on which the SVDD algorithm is improved and achieves excellent fault detection performance.By incorporating faulty samples into the underlying SVDD model,training deals better with the problem of missing detection of faulty samples caused by the imbalance in the distribution of abnormal samples,and the hypersphere boundary ismodified to classify the samplesmore accurately.The Bayesian Optimization NSVDD(BO-NSVDD)model was constructed to quickly and accurately optimize hyperparameter combinations.In the experiments,electric vehicle operation data with four common fault types are used to evaluate the performance with other five models,and the results show that the BO-NSVDD model presents superior detection performance for each type of fault data,especially in the imperceptible early and minor faults,which has seen very obvious advantages.Finally,the strong robustness of the proposed method is verified by adding different intensities of noise in the dataset.展开更多
The deep mining of coal resources is accompanied by severe environmental challenges and various potential engineering hazards.The implementation of NPR(negative Poisson's ratio)bolts are capable of controlling lar...The deep mining of coal resources is accompanied by severe environmental challenges and various potential engineering hazards.The implementation of NPR(negative Poisson's ratio)bolts are capable of controlling large deformations in the surrounding rock effectively.This paper focuses on studying the mechanical properties of the NPR bolt under static disturbance load.The deep nonlinear mechanical experimental system was used to study the mechanical behavior of rock samples with different anchored types(unanchored/PR anchored/2G NPR anchored)under static disturbance load.The whole process of rock samples was taken by high-speed camera to obtain the real-time failure characteristics under static disturbance load.At the same time,the acoustic emission signal was collected to obtain the key characteristic parameters of acoustic emission such as acoustic emission count,energy,and frequency.The deformation at the failure of the samples was calculated and analyzed by digital speckle software.The findings indicate that the failure mode of rock is influenced by different types of anchoring.The peak failure strength of 2G NPR bolt anchored rock samples exhibits an increase of 6.5%when compared to the unanchored rock samples.The cumulative count and cumulative energy of acoustic emission exhibit a decrease of 62.16%and 62.90%,respectively.The maximum deformation of bearing capacity exhibits an increase of 59.27%,while the failure time demonstrates a delay of 42.86%.The peak failure strength of the 2G NPR bolt anchored ones under static disturbance load exhibits an increase of 5.94%when compared to the rock anchored by PR(Poisson's ratio)bolt.The cumulative count and cumulative energy of acoustic emission exhibit a decrease of 47.16%and 43.86%,respectively.The maximum deformation of the bearing capacity exhibits an increase of 50.43%,and the failure time demonstrates a delay of 32%.After anchoring by 2G NPR bolt,anchoring support effectively reduces the risk of damage caused by static disturbance load.These results demonstrate that the support effect of 2G NPR bolt materials surpasses that of PR bolt.展开更多
The strong consistency of M estimator of regression parameter in linear model for φ-mixing samples is discussed by using the classic Rosenthal type inequality. We get the strong consistency of M estimator under lower...The strong consistency of M estimator of regression parameter in linear model for φ-mixing samples is discussed by using the classic Rosenthal type inequality. We get the strong consistency of M estimator under lower moment condition, which generalizes and improves the corresponding ones for independent sequences.展开更多
In the paper,we study the strong uniform consistency for the kernal estimates of random window w■th of density function and its derivatives under the condition that the sequence{X_n}of the ■ are the identically Φ-m...In the paper,we study the strong uniform consistency for the kernal estimates of random window w■th of density function and its derivatives under the condition that the sequence{X_n}of the ■ are the identically Φ-mixing random variabks.展开更多
In order to solve the problems of weak prediction stability and generalization ability of a neural network algorithm model in the yarn quality prediction research for small samples,a prediction model based on an AdaBo...In order to solve the problems of weak prediction stability and generalization ability of a neural network algorithm model in the yarn quality prediction research for small samples,a prediction model based on an AdaBoost algorithm(AdaBoost model) was established.A prediction model based on a linear regression algorithm(LR model) and a prediction model based on a multi-layer perceptron neural network algorithm(MLP model) were established for comparison.The prediction experiments of the yarn evenness and the yarn strength were implemented.Determination coefficients and prediction errors were used to evaluate the prediction accuracy of these models,and the K-fold cross validation was used to evaluate the generalization ability of these models.In the prediction experiments,the determination coefficient of the yarn evenness prediction result of the AdaBoost model is 76% and 87% higher than that of the LR model and the MLP model,respectively.The determination coefficient of the yarn strength prediction result of the AdaBoost model is slightly higher than that of the other two models.Considering that the yarn evenness dataset has a weaker linear relationship with the cotton dataset than that of the yarn strength dataset in this paper,the AdaBoost model has the best adaptability for the nonlinear dataset among the three models.In addition,the AdaBoost model shows generally better results in the cross-validation experiments and the series of prediction experiments at eight different training set sample sizes.It is proved that the AdaBoost model not only has good prediction accuracy but also has good prediction stability and generalization ability for small samples.展开更多
The aim of this study is to investigate the impacts of the sampling strategy of landslide and non-landslide on the performance of landslide susceptibility assessment(LSA).The study area is the Feiyun catchment in Wenz...The aim of this study is to investigate the impacts of the sampling strategy of landslide and non-landslide on the performance of landslide susceptibility assessment(LSA).The study area is the Feiyun catchment in Wenzhou City,Southeast China.Two types of landslides samples,combined with seven non-landslide sampling strategies,resulted in a total of 14 scenarios.The corresponding landslide susceptibility map(LSM)for each scenario was generated using the random forest model.The receiver operating characteristic(ROC)curve and statistical indicators were calculated and used to assess the impact of the dataset sampling strategy.The results showed that higher accuracies were achieved when using the landslide core as positive samples,combined with non-landslide sampling from the very low zone or buffer zone.The results reveal the influence of landslide and non-landslide sampling strategies on the accuracy of LSA,which provides a reference for subsequent researchers aiming to obtain a more reasonable LSM.展开更多
Global variance reduction is a bottleneck in Monte Carlo shielding calculations.The global variance reduction problem requires that the statistical error of the entire space is uniform.This study proposed a grid-AIS m...Global variance reduction is a bottleneck in Monte Carlo shielding calculations.The global variance reduction problem requires that the statistical error of the entire space is uniform.This study proposed a grid-AIS method for the global variance reduction problem based on the AIS method,which was implemented in the Monte Carlo program MCShield.The proposed method was validated using the VENUS-Ⅲ international benchmark problem and a self-shielding calculation example.The results from the VENUS-Ⅲ benchmark problem showed that the grid-AIS method achieved a significant reduction in the variance of the statistical errors of the MESH grids,decreasing from 1.08×10^(-2) to 3.84×10^(-3),representing a 64.00% reduction.This demonstrates that the grid-AIS method is effective in addressing global issues.The results of the selfshielding calculation demonstrate that the grid-AIS method produced accurate computational results.Moreover,the grid-AIS method exhibited a computational efficiency approximately one order of magnitude higher than that of the AIS method and approximately two orders of magnitude higher than that of the conventional Monte Carlo method.展开更多
Accurate prediction of the internal corrosion rates of oil and gas pipelines could be an effective way to prevent pipeline leaks.In this study,a proposed framework for predicting corrosion rates under a small sample o...Accurate prediction of the internal corrosion rates of oil and gas pipelines could be an effective way to prevent pipeline leaks.In this study,a proposed framework for predicting corrosion rates under a small sample of metal corrosion data in the laboratory was developed to provide a new perspective on how to solve the problem of pipeline corrosion under the condition of insufficient real samples.This approach employed the bagging algorithm to construct a strong learner by integrating several KNN learners.A total of 99 data were collected and split into training and test set with a 9:1 ratio.The training set was used to obtain the best hyperparameters by 10-fold cross-validation and grid search,and the test set was used to determine the performance of the model.The results showed that theMean Absolute Error(MAE)of this framework is 28.06%of the traditional model and outperforms other ensemblemethods.Therefore,the proposed framework is suitable formetal corrosion prediction under small sample conditions.展开更多
Lymnaeid snails are key intermediate hosts for the development and survival of Fasciola spp.,the causative agent of Fascioliasis which are economically important parasites infecting humans and livestock globally.The c...Lymnaeid snails are key intermediate hosts for the development and survival of Fasciola spp.,the causative agent of Fascioliasis which are economically important parasites infecting humans and livestock globally.The current control method for treating Fascioliasis is heavily reliant on anthelmintic drugs,particularly Triclabendazole(TCBZ)which has resulted in drug-resistant parasites and poses significant risk as there are no long-term efficacious alternatives available.Sustainable control measures at the farm level could include both parasite and snail control will play an important role in Fasciola spp.control and reduce the reliance on anthelmintic drugs.Implementation of such sustainable control measures requires effective identification of snails on the property however Lymnaeid snails are small and difficult to physically locate.Snail identification using an environmental DNA approach is a recent approach in which physically locating snails are not required.Austropeplea tomentosa,is the primary intermediate snail host for F.hepatica transmission in South-East Australia and we present an in-field loop-mediated isothermal amplification and water filtering method for the detection of A.tomentosa eDNA from water samples to improve current surveillance methods.This methodology is highly sensitive with a detection limit of 5×10^(−6)ng/μL,detected in<20 minutes,with cumulative sample preparation and amplification time under 1 hour.This proposed workflow could assist in monitoring areas to determine the risk of Fascioliasis infection and implement strategies to manage snail populations to ultimately reduce the risk of infection for humans and livestock.展开更多
Stream sediment sampling is a significant tool in geochemical exploration. The stream sediment composition reflects the bedrock geology, overburden cover, and metalliferous mineralization. This research article focuse...Stream sediment sampling is a significant tool in geochemical exploration. The stream sediment composition reflects the bedrock geology, overburden cover, and metalliferous mineralization. This research article focuses on assessing selected trace element concentrations in stream sediments and interpreting their inter-element relationships using multivariate statistical methods. Tagadur Ranganathaswamy Gudda and its surroundings in the Nuggihalli schist belt of southern India have been investigated in the present work. The geology of the study area is complex, with a diverse range of litho units and evidence of strong structural deformation. The area is known for its mineralization potential for chromite, vanadiferous titanomagnetite, and sulfides. The topography of the region is characterized by an undulating terrain with a radial drainage pattern. Most part of the schist belt is soil covered except the Tagadur Ranganathaswamy Gudda area. For this study, a discrete stream sediment sampling method was adopted to collect the samples. Stream sediment samples were collected using a discrete sampling method and analyzed for trace elements using an ICP-AES spectrophotometer: Fe, Cr, Ti, V, Cu, Ni, Zn, Pb, Mn, Cd, and As have been analyzed. The analytical data were statistically treated using the SPSS software, including descriptive statistics, normalization of data using natural log transformation, and factor analysis with varimax rotation. The transformed data showed a log-normal distribution, indicating the presence of geochemical anomalies. The results of the study provide valuable insights into the geochemical processes and mineralization potential of the study area. The statistical analysis helps in understanding the inter-element relationships and identifying element groups and their implications on bedrock potential mineralization. Additionally, spatial analysis using inverse distance weighting interpolation provides information about the distribution of geochemical parameters across the study area. Overall, this research contributes to the understanding of stream sediment geochemistry and its application in mineral exploration. The findings have implications for future exploration efforts and can aid in the identification of potential ore deposits in the Nuggihalli schist belt and similar geological settings.展开更多
In this paper,we establish a new multivariate Hermite sampling series involving samples from the function itself and its mixed and non-mixed partial derivatives of arbitrary order.This multivariate form of Hermite sam...In this paper,we establish a new multivariate Hermite sampling series involving samples from the function itself and its mixed and non-mixed partial derivatives of arbitrary order.This multivariate form of Hermite sampling will be valid for some classes of multivariate entire functions,satisfying certain growth conditions.We will show that many known results included in Commun Korean Math Soc,2002,17:731-740,Turk J Math,2017,41:387-403 and Filomat,2020,34:3339-3347 are special cases of our results.Moreover,we estimate the truncation error of this sampling based on localized sampling without decay assumption.Illustrative examples are also presented.展开更多
Objective Liver transplantation is a current treatment option for hepatocellular carcinoma(HCC).The United States National Inpatient Sample database was utilized to identify risk factors that influence the outcome of ...Objective Liver transplantation is a current treatment option for hepatocellular carcinoma(HCC).The United States National Inpatient Sample database was utilized to identify risk factors that influence the outcome of liver transplantation,including locoregional recurrence,distant metastasis,and in-hospital mortality,in HCC patients with concurrent hepatitis B infection,hepatitis C infection,or alcoholic cirrhosis.Methods This retrospective cohort study included HCC patients(n=2391)from the National Inpatient Sample database who underwent liver transplantation and were diagnosed with hepatitis B or C virus infection,co-infection with hepatitis B and C,or alcoholic cirrhosis of the liver between 2005 and 2014.Associations between HCC etiology and post-transplant outcomes were examined with multivariate analysis models.Results Liver cirrhosis was due to alcohol in 10.5%of patients,hepatitis B in 6.6%,hepatitis C in 10.8%,and combined hepatitis B and C infection in 24.3%.Distant metastasis was found in 16.7%of patients infected with hepatitis B and 9%of hepatitis C patients.Local recurrence of HCC was significantly more likely to occur in patients with hepatitis B than in those with alcohol-induced disease.Conclusion After liver transplantation,patients with hepatitis B infection have a higher risk of local recurrence and distant metastasis.Postoperative care and patient tracking are essential for liver transplant patients with hepatitis B infection.展开更多
This study presents the design of a modified attributed control chart based on a double sampling(DS)np chart applied in combination with generalized multiple dependent state(GMDS)sampling to monitor the mean life of t...This study presents the design of a modified attributed control chart based on a double sampling(DS)np chart applied in combination with generalized multiple dependent state(GMDS)sampling to monitor the mean life of the product based on the time truncated life test employing theWeibull distribution.The control chart developed supports the examination of the mean lifespan variation for a particular product in the process of manufacturing.Three control limit levels are used:the warning control limit,inner control limit,and outer control limit.Together,they enhance the capability for variation detection.A genetic algorithm can be used for optimization during the in-control process,whereby the optimal parameters can be established for the proposed control chart.The control chart performance is assessed using the average run length,while the influence of the model parameters upon the control chart solution is assessed via sensitivity analysis based on an orthogonal experimental design withmultiple linear regression.A comparative study was conducted based on the out-of-control average run length,in which the developed control chart offered greater sensitivity in the detection of process shifts while making use of smaller samples on average than is the case for existing control charts.Finally,to exhibit the utility of the developed control chart,this paper presents its application using simulated data with parameters drawn from the real set of data.展开更多
We conduct an experimental study supported by theoretical analysis of single laser ablating copper to investigate the interactions between laser and material at different sample temperatures,and predict the changes of...We conduct an experimental study supported by theoretical analysis of single laser ablating copper to investigate the interactions between laser and material at different sample temperatures,and predict the changes of ablation morphology and lattice temperature.For investigating the effect of sample temperature on femtosecond laser processing,we conduct experiments on and simulate the thermal behavior of femtosecond laser irradiating copper by using a two-temperature model.The simulation results show that both electron peak temperature and the relaxation time needed to reach equilibrium increase as initial sample temperature rises.When the sample temperature rises from 300 K to 600 K,the maximum lattice temperature of the copper surface increases by about 6500 K under femtosecond laser irradiation,and the ablation depth increases by 20%.The simulated ablation depths follow the same general trend as the experimental values.This work provides some theoretical basis and technical support for developing femtosecond laser processing in the field of metal materials.展开更多
The rapid advancement and broad application of machine learning(ML)have driven a groundbreaking revolution in computational biology.One of the most cutting-edge and important applications of ML is its integration with...The rapid advancement and broad application of machine learning(ML)have driven a groundbreaking revolution in computational biology.One of the most cutting-edge and important applications of ML is its integration with molecular simulations to improve the sampling efficiency of the vast conformational space of large biomolecules.This review focuses on recent studies that utilize ML-based techniques in the exploration of protein conformational landscape.We first highlight the recent development of ML-aided enhanced sampling methods,including heuristic algorithms and neural networks that are designed to refine the selection of reaction coordinates for the construction of bias potential,or facilitate the exploration of the unsampled region of the energy landscape.Further,we review the development of autoencoder based methods that combine molecular simulations and deep learning to expand the search for protein conformations.Lastly,we discuss the cutting-edge methodologies for the one-shot generation of protein conformations with precise Boltzmann weights.Collectively,this review demonstrates the promising potential of machine learning in revolutionizing our insight into the complex conformational ensembles of proteins.展开更多
The advent of self-attention mechanisms within Transformer models has significantly propelled the advancement of deep learning algorithms,yielding outstanding achievements across diverse domains.Nonetheless,self-atten...The advent of self-attention mechanisms within Transformer models has significantly propelled the advancement of deep learning algorithms,yielding outstanding achievements across diverse domains.Nonetheless,self-attention mechanisms falter when applied to datasets with intricate semantic content and extensive dependency structures.In response,this paper introduces a Diffusion Sampling and Label-Driven Co-attention Neural Network(DSLD),which adopts a diffusion sampling method to capture more comprehensive semantic information of the data.Additionally,themodel leverages the joint correlation information of labels and data to introduce the computation of text representation,correcting semantic representationbiases in thedata,andincreasing the accuracyof semantic representation.Ultimately,the model computes the corresponding classification results by synthesizing these rich data semantic representations.Experiments on seven benchmark datasets show that our proposed model achieves competitive results compared to state-of-the-art methods.展开更多
基金Supported by Research Foundation of CLEP of China (Grant No.TY3Q20110003)。
文摘The encapsulation of lunar samples is a core research area in the third phase of the Chinese Lunar Exploration Program.The seal assembly,opening and closing mechanism(OCM),and locking mechanism are the core components of the encapsulation device of the lunar samples,and the requirements of a tight seal,lightweight,and low power make the design of these core components difficult.In this study,a combined sealing assembly,OCM,and locking mechanism were investigated for the device.The sealing architecture consists of rubber and an Ag-In alloy,and a theory was built to analyze the seal.Experiments of the electroplate Au coating on the knife-edge revealed that the hermetic seal can be significantly improved.The driving principle for coaxial double-helical pairs was investigated and used to design the OCM.Moreover,a locking mechanism was created using an electric initiating explosive device with orifice damping.By optimizing the design,the output parameters were adjusted to meet the requirements of the lunar explorer.The experimental results showed that the helium leak rate of the test pieces were not more than 5×10^(-11) Pa·m^(3)·s^(-1),the minimum power of the OCM was 0.3 W,and the total weight of the principle prototype was 2.9 kg.The explosive driven locking mechanism has low impact.This investigation solved the difficulties in achieving tight seal,light weight,and low power for the lunar explorer,and the results can also be used to explore other extraterrestrial objects in the future.
基金funded by the grants from the National Key Research and Development Program of China[2021YFC2301503,2022YFC2302900]the National Natural and Science Foundation of China[82171739,82171815,81873884]。
文摘Objective To evaluate the diagnostic value of histopathological examination of ultrasound-guided puncture biopsy samples in extrapulmonary tuberculosis(EPTB).Methods This study was conducted at the Shanghai Public Health Clinical Center.A total of 115patients underwent ultrasound-guided puncture biopsy,followed by MGIT 960 culture(culture),smear,Gene Xpert MTB/RIF(Xpert),and histopathological examination.These assays were performed to evaluate their effectiveness in diagnosing EPTB in comparison to two different diagnostic criteria:liquid culture and composite reference standard(CRS).Results When CRS was used as the reference standard,the sensitivity and specificity of culture,smear,Xpert,and histopathological examination were(44.83%,89.29%),(51.72%,89.29%),(70.11%,96.43%),and(85.06%,82.14%),respectively.Based on liquid culture tests,the sensitivity and specificity of smear,Xpert,and pathological examination were(66.67%,72.60%),(83.33%,63.01%),and(92.86%,45.21%),respectively.Histopathological examination showed the highest sensitivity but lowest specificity.Further,we found that the combination of Xpert and histopathological examination showed a sensitivity of 90.80%and a specificity of 89.29%.Conclusion Ultrasound-guided puncture sampling is safe and effective for the diagnosis of EPTB.Compared with culture,smear,and Xpert,histopathological examination showed higher sensitivity but lower specificity.The combination of histopathology with Xpert showed the best performance characteristics.
基金supported by the National Key Research and Development Program (2022YFF0609504)the National Natural Science Foundation of China (61974126,51902273,62005230,62001405)the Natural Science Foundation of Fujian Province of China (No.2021J06009)
文摘Perovskite solar cells(PsCs)have developed tremendously over the past decade.However,the key factors influencing the power conversion efficiency(PCE)of PSCs remain incompletely understood,due to the complexity and coupling of these structural and compositional parameters.In this research,we demon-strate an effective approach to optimize PSCs performance via machine learning(ML).To address chal-lenges posed by limited samples,we propose a feature mask(FM)method,which augments training samples through feature transformation rather than synthetic data.Using this approach,squeeze-and-excitation residual network(SEResNet)model achieves an accuracy with a root-mean-square-error(RMSE)of 0.833%and a Pearson's correlation coefficient(r)of 0.980.Furthermore,we employ the permu-tation importance(PI)algorithm to investigate key features for PCE.Subsequently,we predict PCE through high-throughput screenings,in which we study the relationship between PCE and chemical com-positions.After that,we conduct experiments to validate the consistency between predicted results by ML and experimental results.In this work,ML demonstrates the capability to predict device performance,extract key parameters from complex systems,and accelerate the transition from laboratory findings to commercialapplications.
基金supported partially by NationalNatural Science Foundation of China(NSFC)(No.U21A20146)Collaborative Innovation Project of Anhui Universities(No.GXXT-2020-070)+8 种基金Cooperation Project of Anhui Future Technology Research Institute and Enterprise(No.2023qyhz32)Development of a New Dynamic Life Prediction Technology for Energy Storage Batteries(No.KH10003598)Opening Project of Key Laboratory of Electric Drive and Control of Anhui Province(No.DQKJ202304)Anhui Provincial Department of Education New Era Education Quality Project(No.2023dshwyx019)Special Fund for Collaborative Innovation between Anhui Polytechnic University and Jiujiang District(No.2022cyxtb10)Key Research and Development Program of Wuhu City(No.2022yf42)Open Research Fund of Anhui Key Laboratory of Detection Technology and Energy Saving Devices(No.JCKJ2021B06)Anhui Provincial Graduate Student Innovation and Entrepreneurship Practice Project(No.2022cxcysj123)Key Scientific Research Project for Anhui Universities(No.2022AH050981).
文摘Accurate and reliable fault detection is essential for the safe operation of electric vehicles.Support vector data description(SVDD)has been widely used in the field of fault detection.However,constructing the hypersphere boundary only describes the distribution of unlabeled samples,while the distribution of faulty samples cannot be effectively described and easilymisses detecting faulty data due to the imbalance of sample distribution.Meanwhile,selecting parameters is critical to the detection performance,and empirical parameterization is generally timeconsuming and laborious and may not result in finding the optimal parameters.Therefore,this paper proposes a semi-supervised data-driven method based on which the SVDD algorithm is improved and achieves excellent fault detection performance.By incorporating faulty samples into the underlying SVDD model,training deals better with the problem of missing detection of faulty samples caused by the imbalance in the distribution of abnormal samples,and the hypersphere boundary ismodified to classify the samplesmore accurately.The Bayesian Optimization NSVDD(BO-NSVDD)model was constructed to quickly and accurately optimize hyperparameter combinations.In the experiments,electric vehicle operation data with four common fault types are used to evaluate the performance with other five models,and the results show that the BO-NSVDD model presents superior detection performance for each type of fault data,especially in the imperceptible early and minor faults,which has seen very obvious advantages.Finally,the strong robustness of the proposed method is verified by adding different intensities of noise in the dataset.
基金provided by the National Natural Science Foundation of China(52074300)the Program of China Scholarship Council(202206430024)+2 种基金the National Natural Science Foundation of China Youth Science(52104139)Yueqi Young Scholars Project of China University of Mining and Technology Beijing(2602021RC84)Guizhou province science and technology planning project([2020]3007,[2020]3008)。
文摘The deep mining of coal resources is accompanied by severe environmental challenges and various potential engineering hazards.The implementation of NPR(negative Poisson's ratio)bolts are capable of controlling large deformations in the surrounding rock effectively.This paper focuses on studying the mechanical properties of the NPR bolt under static disturbance load.The deep nonlinear mechanical experimental system was used to study the mechanical behavior of rock samples with different anchored types(unanchored/PR anchored/2G NPR anchored)under static disturbance load.The whole process of rock samples was taken by high-speed camera to obtain the real-time failure characteristics under static disturbance load.At the same time,the acoustic emission signal was collected to obtain the key characteristic parameters of acoustic emission such as acoustic emission count,energy,and frequency.The deformation at the failure of the samples was calculated and analyzed by digital speckle software.The findings indicate that the failure mode of rock is influenced by different types of anchoring.The peak failure strength of 2G NPR bolt anchored rock samples exhibits an increase of 6.5%when compared to the unanchored rock samples.The cumulative count and cumulative energy of acoustic emission exhibit a decrease of 62.16%and 62.90%,respectively.The maximum deformation of bearing capacity exhibits an increase of 59.27%,while the failure time demonstrates a delay of 42.86%.The peak failure strength of the 2G NPR bolt anchored ones under static disturbance load exhibits an increase of 5.94%when compared to the rock anchored by PR(Poisson's ratio)bolt.The cumulative count and cumulative energy of acoustic emission exhibit a decrease of 47.16%and 43.86%,respectively.The maximum deformation of the bearing capacity exhibits an increase of 50.43%,and the failure time demonstrates a delay of 32%.After anchoring by 2G NPR bolt,anchoring support effectively reduces the risk of damage caused by static disturbance load.These results demonstrate that the support effect of 2G NPR bolt materials surpasses that of PR bolt.
基金The NSF (11201001,11171001,11126176) of Chinathe NSF (1208085QA03) of Anhui Province+2 种基金Provincial Natural Science Research Project (KJ2010A005) of Anhui CollegesDoctoral Research Start-up Funds Projects of Anhui Universitythe Students’ Innovative Training Project (2012003) of Anhui University
文摘The strong consistency of M estimator of regression parameter in linear model for φ-mixing samples is discussed by using the classic Rosenthal type inequality. We get the strong consistency of M estimator under lower moment condition, which generalizes and improves the corresponding ones for independent sequences.
基金supported by Natural Science Foun■ion of Henan P■visial Commission of Bdusation
文摘In the paper,we study the strong uniform consistency for the kernal estimates of random window w■th of density function and its derivatives under the condition that the sequence{X_n}of the ■ are the identically Φ-mixing random variabks.
文摘In order to solve the problems of weak prediction stability and generalization ability of a neural network algorithm model in the yarn quality prediction research for small samples,a prediction model based on an AdaBoost algorithm(AdaBoost model) was established.A prediction model based on a linear regression algorithm(LR model) and a prediction model based on a multi-layer perceptron neural network algorithm(MLP model) were established for comparison.The prediction experiments of the yarn evenness and the yarn strength were implemented.Determination coefficients and prediction errors were used to evaluate the prediction accuracy of these models,and the K-fold cross validation was used to evaluate the generalization ability of these models.In the prediction experiments,the determination coefficient of the yarn evenness prediction result of the AdaBoost model is 76% and 87% higher than that of the LR model and the MLP model,respectively.The determination coefficient of the yarn strength prediction result of the AdaBoost model is slightly higher than that of the other two models.Considering that the yarn evenness dataset has a weaker linear relationship with the cotton dataset than that of the yarn strength dataset in this paper,the AdaBoost model has the best adaptability for the nonlinear dataset among the three models.In addition,the AdaBoost model shows generally better results in the cross-validation experiments and the series of prediction experiments at eight different training set sample sizes.It is proved that the AdaBoost model not only has good prediction accuracy but also has good prediction stability and generalization ability for small samples.
文摘The aim of this study is to investigate the impacts of the sampling strategy of landslide and non-landslide on the performance of landslide susceptibility assessment(LSA).The study area is the Feiyun catchment in Wenzhou City,Southeast China.Two types of landslides samples,combined with seven non-landslide sampling strategies,resulted in a total of 14 scenarios.The corresponding landslide susceptibility map(LSM)for each scenario was generated using the random forest model.The receiver operating characteristic(ROC)curve and statistical indicators were calculated and used to assess the impact of the dataset sampling strategy.The results showed that higher accuracies were achieved when using the landslide core as positive samples,combined with non-landslide sampling from the very low zone or buffer zone.The results reveal the influence of landslide and non-landslide sampling strategies on the accuracy of LSA,which provides a reference for subsequent researchers aiming to obtain a more reasonable LSM.
基金supported by the Platform Development Foundation of the China Institute for Radiation Protection(No.YP21030101)the National Natural Science Foundation of China(General Program)(Nos.12175114,U2167209)+1 种基金the National Key R&D Program of China(No.2021YFF0603600)the Tsinghua University Initiative Scientific Research Program(No.20211080081).
文摘Global variance reduction is a bottleneck in Monte Carlo shielding calculations.The global variance reduction problem requires that the statistical error of the entire space is uniform.This study proposed a grid-AIS method for the global variance reduction problem based on the AIS method,which was implemented in the Monte Carlo program MCShield.The proposed method was validated using the VENUS-Ⅲ international benchmark problem and a self-shielding calculation example.The results from the VENUS-Ⅲ benchmark problem showed that the grid-AIS method achieved a significant reduction in the variance of the statistical errors of the MESH grids,decreasing from 1.08×10^(-2) to 3.84×10^(-3),representing a 64.00% reduction.This demonstrates that the grid-AIS method is effective in addressing global issues.The results of the selfshielding calculation demonstrate that the grid-AIS method produced accurate computational results.Moreover,the grid-AIS method exhibited a computational efficiency approximately one order of magnitude higher than that of the AIS method and approximately two orders of magnitude higher than that of the conventional Monte Carlo method.
基金supported by the National Natural Science Foundation of China(Grant No.52174062).
文摘Accurate prediction of the internal corrosion rates of oil and gas pipelines could be an effective way to prevent pipeline leaks.In this study,a proposed framework for predicting corrosion rates under a small sample of metal corrosion data in the laboratory was developed to provide a new perspective on how to solve the problem of pipeline corrosion under the condition of insufficient real samples.This approach employed the bagging algorithm to construct a strong learner by integrating several KNN learners.A total of 99 data were collected and split into training and test set with a 9:1 ratio.The training set was used to obtain the best hyperparameters by 10-fold cross-validation and grid search,and the test set was used to determine the performance of the model.The results showed that theMean Absolute Error(MAE)of this framework is 28.06%of the traditional model and outperforms other ensemblemethods.Therefore,the proposed framework is suitable formetal corrosion prediction under small sample conditions.
基金supported by Cooperative Research Centres Project(CRCP)awarded to Geneworks and La Trobe University.L.T.is supported by an Australian Research Training Program scholarship and the Tim Healy Memorial Scholarship awarded by The Department of Primary Industries South Australia(PIRSA).
文摘Lymnaeid snails are key intermediate hosts for the development and survival of Fasciola spp.,the causative agent of Fascioliasis which are economically important parasites infecting humans and livestock globally.The current control method for treating Fascioliasis is heavily reliant on anthelmintic drugs,particularly Triclabendazole(TCBZ)which has resulted in drug-resistant parasites and poses significant risk as there are no long-term efficacious alternatives available.Sustainable control measures at the farm level could include both parasite and snail control will play an important role in Fasciola spp.control and reduce the reliance on anthelmintic drugs.Implementation of such sustainable control measures requires effective identification of snails on the property however Lymnaeid snails are small and difficult to physically locate.Snail identification using an environmental DNA approach is a recent approach in which physically locating snails are not required.Austropeplea tomentosa,is the primary intermediate snail host for F.hepatica transmission in South-East Australia and we present an in-field loop-mediated isothermal amplification and water filtering method for the detection of A.tomentosa eDNA from water samples to improve current surveillance methods.This methodology is highly sensitive with a detection limit of 5×10^(−6)ng/μL,detected in<20 minutes,with cumulative sample preparation and amplification time under 1 hour.This proposed workflow could assist in monitoring areas to determine the risk of Fascioliasis infection and implement strategies to manage snail populations to ultimately reduce the risk of infection for humans and livestock.
文摘Stream sediment sampling is a significant tool in geochemical exploration. The stream sediment composition reflects the bedrock geology, overburden cover, and metalliferous mineralization. This research article focuses on assessing selected trace element concentrations in stream sediments and interpreting their inter-element relationships using multivariate statistical methods. Tagadur Ranganathaswamy Gudda and its surroundings in the Nuggihalli schist belt of southern India have been investigated in the present work. The geology of the study area is complex, with a diverse range of litho units and evidence of strong structural deformation. The area is known for its mineralization potential for chromite, vanadiferous titanomagnetite, and sulfides. The topography of the region is characterized by an undulating terrain with a radial drainage pattern. Most part of the schist belt is soil covered except the Tagadur Ranganathaswamy Gudda area. For this study, a discrete stream sediment sampling method was adopted to collect the samples. Stream sediment samples were collected using a discrete sampling method and analyzed for trace elements using an ICP-AES spectrophotometer: Fe, Cr, Ti, V, Cu, Ni, Zn, Pb, Mn, Cd, and As have been analyzed. The analytical data were statistically treated using the SPSS software, including descriptive statistics, normalization of data using natural log transformation, and factor analysis with varimax rotation. The transformed data showed a log-normal distribution, indicating the presence of geochemical anomalies. The results of the study provide valuable insights into the geochemical processes and mineralization potential of the study area. The statistical analysis helps in understanding the inter-element relationships and identifying element groups and their implications on bedrock potential mineralization. Additionally, spatial analysis using inverse distance weighting interpolation provides information about the distribution of geochemical parameters across the study area. Overall, this research contributes to the understanding of stream sediment geochemistry and its application in mineral exploration. The findings have implications for future exploration efforts and can aid in the identification of potential ore deposits in the Nuggihalli schist belt and similar geological settings.
文摘In this paper,we establish a new multivariate Hermite sampling series involving samples from the function itself and its mixed and non-mixed partial derivatives of arbitrary order.This multivariate form of Hermite sampling will be valid for some classes of multivariate entire functions,satisfying certain growth conditions.We will show that many known results included in Commun Korean Math Soc,2002,17:731-740,Turk J Math,2017,41:387-403 and Filomat,2020,34:3339-3347 are special cases of our results.Moreover,we estimate the truncation error of this sampling based on localized sampling without decay assumption.Illustrative examples are also presented.
基金This study was supported by the Chen Xiao-Ping Foundation for the Development of Science and Technology of Hubei Province(No.CXPJJH11900001-2019210).
文摘Objective Liver transplantation is a current treatment option for hepatocellular carcinoma(HCC).The United States National Inpatient Sample database was utilized to identify risk factors that influence the outcome of liver transplantation,including locoregional recurrence,distant metastasis,and in-hospital mortality,in HCC patients with concurrent hepatitis B infection,hepatitis C infection,or alcoholic cirrhosis.Methods This retrospective cohort study included HCC patients(n=2391)from the National Inpatient Sample database who underwent liver transplantation and were diagnosed with hepatitis B or C virus infection,co-infection with hepatitis B and C,or alcoholic cirrhosis of the liver between 2005 and 2014.Associations between HCC etiology and post-transplant outcomes were examined with multivariate analysis models.Results Liver cirrhosis was due to alcohol in 10.5%of patients,hepatitis B in 6.6%,hepatitis C in 10.8%,and combined hepatitis B and C infection in 24.3%.Distant metastasis was found in 16.7%of patients infected with hepatitis B and 9%of hepatitis C patients.Local recurrence of HCC was significantly more likely to occur in patients with hepatitis B than in those with alcohol-induced disease.Conclusion After liver transplantation,patients with hepatitis B infection have a higher risk of local recurrence and distant metastasis.Postoperative care and patient tracking are essential for liver transplant patients with hepatitis B infection.
基金the Science,Research and Innovation Promotion Funding(TSRI)(Grant No.FRB660012/0168)managed under Rajamangala University of Technology Thanyaburi(FRB66E0646O.4).
文摘This study presents the design of a modified attributed control chart based on a double sampling(DS)np chart applied in combination with generalized multiple dependent state(GMDS)sampling to monitor the mean life of the product based on the time truncated life test employing theWeibull distribution.The control chart developed supports the examination of the mean lifespan variation for a particular product in the process of manufacturing.Three control limit levels are used:the warning control limit,inner control limit,and outer control limit.Together,they enhance the capability for variation detection.A genetic algorithm can be used for optimization during the in-control process,whereby the optimal parameters can be established for the proposed control chart.The control chart performance is assessed using the average run length,while the influence of the model parameters upon the control chart solution is assessed via sensitivity analysis based on an orthogonal experimental design withmultiple linear regression.A comparative study was conducted based on the out-of-control average run length,in which the developed control chart offered greater sensitivity in the detection of process shifts while making use of smaller samples on average than is the case for existing control charts.Finally,to exhibit the utility of the developed control chart,this paper presents its application using simulated data with parameters drawn from the real set of data.
基金Project supported by the National Key Research and Development Program of China(Grant No.2019YFA0307701)the National Natural Science Foundation of China(Grant Nos.11674128,11674124,and 11974138).
文摘We conduct an experimental study supported by theoretical analysis of single laser ablating copper to investigate the interactions between laser and material at different sample temperatures,and predict the changes of ablation morphology and lattice temperature.For investigating the effect of sample temperature on femtosecond laser processing,we conduct experiments on and simulate the thermal behavior of femtosecond laser irradiating copper by using a two-temperature model.The simulation results show that both electron peak temperature and the relaxation time needed to reach equilibrium increase as initial sample temperature rises.When the sample temperature rises from 300 K to 600 K,the maximum lattice temperature of the copper surface increases by about 6500 K under femtosecond laser irradiation,and the ablation depth increases by 20%.The simulated ablation depths follow the same general trend as the experimental values.This work provides some theoretical basis and technical support for developing femtosecond laser processing in the field of metal materials.
基金Project supported by the National Key Research and Development Program of China(Grant No.2023YFF1204402)the National Natural Science Foundation of China(Grant Nos.12074079 and 12374208)+1 种基金the Natural Science Foundation of Shanghai(Grant No.22ZR1406800)the China Postdoctoral Science Foundation(Grant No.2022M720815).
文摘The rapid advancement and broad application of machine learning(ML)have driven a groundbreaking revolution in computational biology.One of the most cutting-edge and important applications of ML is its integration with molecular simulations to improve the sampling efficiency of the vast conformational space of large biomolecules.This review focuses on recent studies that utilize ML-based techniques in the exploration of protein conformational landscape.We first highlight the recent development of ML-aided enhanced sampling methods,including heuristic algorithms and neural networks that are designed to refine the selection of reaction coordinates for the construction of bias potential,or facilitate the exploration of the unsampled region of the energy landscape.Further,we review the development of autoencoder based methods that combine molecular simulations and deep learning to expand the search for protein conformations.Lastly,we discuss the cutting-edge methodologies for the one-shot generation of protein conformations with precise Boltzmann weights.Collectively,this review demonstrates the promising potential of machine learning in revolutionizing our insight into the complex conformational ensembles of proteins.
基金the Communication University of China(CUC230A013)the Fundamental Research Funds for the Central Universities.
文摘The advent of self-attention mechanisms within Transformer models has significantly propelled the advancement of deep learning algorithms,yielding outstanding achievements across diverse domains.Nonetheless,self-attention mechanisms falter when applied to datasets with intricate semantic content and extensive dependency structures.In response,this paper introduces a Diffusion Sampling and Label-Driven Co-attention Neural Network(DSLD),which adopts a diffusion sampling method to capture more comprehensive semantic information of the data.Additionally,themodel leverages the joint correlation information of labels and data to introduce the computation of text representation,correcting semantic representationbiases in thedata,andincreasing the accuracyof semantic representation.Ultimately,the model computes the corresponding classification results by synthesizing these rich data semantic representations.Experiments on seven benchmark datasets show that our proposed model achieves competitive results compared to state-of-the-art methods.