The purpose of the research in the NJIKI’s fundamental THEOREM-DEFINITION on fractions in the mathematical set ℚand by extension in ℝand ℂand in order to construct some algebraic structures is about the proved EXISTE...The purpose of the research in the NJIKI’s fundamental THEOREM-DEFINITION on fractions in the mathematical set ℚand by extension in ℝand ℂand in order to construct some algebraic structures is about the proved EXISTENCE and the DEFINITION by NJIKI of two INNOVATIVE, IMPORTANT and TEACHABLE operations of addition or additive operations, in ℚ, marked ⊕and +α,β, and taken as VECTORIAL, TRIANGULAR, of THREE or PROPORTIONAL operations and in order to make THEM not be different from the RATIONAL ONE, +, but to bring much more and new information on fractions, and, by extension in ℝand ℂ. And the very NJIKI’s fundamental THEOREM-DEFINITION having many APPLICATIONS in the everyday life of the HUMAN BEINGS and without talking about computer sciences, henceforth being supplied with very interesting new ALGORITHMS. And as for the work done in the research, it will be waiting for its extension to be done after publication and along with the research results concerned.展开更多
Through reviewing domestic and overseas literatures about the definition of urban-rural fringe,it can be found that the combination of qualitative and quantitative definition methods has become a dominant one.This pap...Through reviewing domestic and overseas literatures about the definition of urban-rural fringe,it can be found that the combination of qualitative and quantitative definition methods has become a dominant one.This paper makes out the principle and basis,uses the data of villages and towns,and establishes an index system from three angles:population,land use and landscape.And then the gravitational model is applied to define the urban-rural fringe with Beijing as an example.展开更多
In nature, to realize the smooth motion for different speeds, the continuous gait transition is usually required for the quadrupeds. Thus, the gait simulation of quadrupeds is a requisite step to obtain the stable and...In nature, to realize the smooth motion for different speeds, the continuous gait transition is usually required for the quadrupeds. Thus, the gait simulation of quadrupeds is a requisite step to obtain the stable and energy-efficient gait for the walking machines. In this paper, the definitions of the two gait parameters, phasic difference and duty factor are presented, which can determine the gait of the quadrupeds. Then, several typical gaits of the quadrupeds are analyzed such that the seven standard gaits and corresponding parameters are summarized. Additionally, the variance law of the two parameters, which determine the relationship of gait transition, is analyzed. Furthermore, the quadruped gait derivative spectrum (QGDS) is proposed and the gait definition of the quadrupeds is presented. To minimize the power consumption, the choice criterion of gait, the optimal gait in terms of the motion speed, duty factory, and power consumption for the walking machines, is developed. Last, the continuous variance of the gait is implemented by the simulation of the gait transition from walk to trot, which evaluate the choice criterion and transition of gait.展开更多
A plant-based diet consists of all minimally processedfruits, vegetables, whole grains, legumes, nuts and seeds,herbs, and spices and excludes all animal products, includ-ing red meat, poultry, fish, eggs, and dairy p...A plant-based diet consists of all minimally processedfruits, vegetables, whole grains, legumes, nuts and seeds,herbs, and spices and excludes all animal products, includ-ing red meat, poultry, fish, eggs, and dairy products.展开更多
While the incidence of gastric cancer(GC)in general has decreased worldwide in recent decades,the incidence of diffuse cancer historically comprising poorly cohesive cells-GC(PCC-GC)and including signet ring cell canc...While the incidence of gastric cancer(GC)in general has decreased worldwide in recent decades,the incidence of diffuse cancer historically comprising poorly cohesive cells-GC(PCC-GC)and including signet ring cell cancer is rising.Literature concerning PCC-GC is scarce and unclear,mostly due to a large variety of historically used definitions and classifications.Compared to other histological subtypes of GC,PCC-GC is nevertheless characterized by a distinct set of epidemiological,histological and clinical features which require a specific diagnostic and therapeutic approach.The aim of this review was to provide an update on the definition,classification and therapeutic strategies of PCC-GC.We focus on the updated histological definition of PCC-GC,along with its implications on future treatment strategies and study design.Also,specific considerations in the diagnostic management are discussed.Finally,the impact of some recent developments in the therapeutic management of GC in general such as the recently validated taxane-based regimens(5-Fluorouracil,leucovorin,oxaliplatin and docetaxel),the use of hyperthermic intraperitoneal chemotherapy as well as pressurized intraperitoneal aerosol chemotherapy and targeted therapy have been reviewed in depth for their relative importance for PCC-GC in particular.展开更多
AIM:To develop and validate a case definition of eosinophilic esophagitis(EoE) in the linked Danish health registries.METHODS:For case definition development,we queried the Danish medical registries from 2006-2007 to ...AIM:To develop and validate a case definition of eosinophilic esophagitis(EoE) in the linked Danish health registries.METHODS:For case definition development,we queried the Danish medical registries from 2006-2007 to identify candidate cases of EoE in Northern Denmark.All International Classification of Diseases-10(ICD-10) and prescription codes were obtained,and archived pathology slides were obtained and re-reviewed to determine case status.We used an iterative process to select inclusion/exclusion codes,refine the case definition,and optimize sensitivity and specificity.We then re-queried the registries from 2008-2009 to yield a validation set.The case definition algorithm was applied,and sensitivity and specificity were calculated.RESULTS:Of the 51 and 49 candidate cases identified in both the development and validation sets,21 and 24 had EoE,respectively.Characteristics of EoE cases in the development set [mean age 35 years;76% male;86% dysphagia;103 eosinophils per high-power field(eos/hpf)] were similar to those in the validation set(mean age 42 years;83% male;67% dysphagia;77 eos/hpf).Re-review of archived slides confirmed that the pathology coding for esophageal eosinophilia was correct in greater than 90% of cases.Two registrybased case algorithms based on pathology,ICD-10,and pharmacy codes were successfully generated in the development set,one that was sensitive(90%) and one that was specific(97%).When these algorithms were applied to the validation set,they remained sensitive(88%) and specific(96%).CONCLUSION:Two registry-based definitions,one highly sensitive and one highly specific,were developed and validated for the linked Danish national health databases,making future population-based studies feasible.展开更多
Objectives: We aimed to 1) investigate the prevalence of MS in apparently healthy, non-hypertensive non-diabetic individuals living in Jeddah using the IDF and the NCEP-ATP III criteria to test for agreement in classi...Objectives: We aimed to 1) investigate the prevalence of MS in apparently healthy, non-hypertensive non-diabetic individuals living in Jeddah using the IDF and the NCEP-ATP III criteria to test for agreement in classification, and to determine the characteristics of subjects identified by either definition, and 2) examine the significance of family medical history and life style habits. Methods: 557 apparently healthy individuals aged 18 - 50 y were randomly approached in Jeddah health centres. 412 agreed to participate, while 55 were excluded because they were found to be frankly hypertensive and/or diabetic. Finally, 357 apparently healthy subjects with no hypertension or diabetes were fully studied. Anthropometric and demographic information were collected. Insulin, glucose, and lipid profile were obtained in fasting blood samples. Individuals were identified using the two definitions of metabolic syndrome, and their characteristics were compared statistically to the rest of the population. Results: Of the 233 subjects fulfilling the inclusion criteria, 44 and 39 (18.9% and 16.7%) were identified as having MS by the IDF or ATPIII definitions, respectively. The most common characteristic was central obesity using the IDF definition, and low HDL-cholesterol using the NCEP-ATP III definition. As expected from our exclusion criteria, the least common feature was high blood pressure in both cases. There was no significant difference between subgroups with and without MS with regard to smoking, exercise, and family history of disease. Regression analysis indicated the strongest predictors of MS were: blood glucose, LDL-C/HDL-C ratio and plasma insulin using the NCEP-ATPIII definition, and blood glucose, Waist /Hip ratio and plasma atherogenic index (PAI) using the IDF definition. Conclusions: In the absence of local cut-off thresholds for waist circumference, subjects might escape diagnosis using the IDF definition. The use of waist/Hip ratio, LDL-C: HDL-C, PAI and circulating insulin help with the diagnosis.展开更多
In this note, we analyze a few major claims about . As a consequence, we rewrite a major theorem, nullify its proof and one remark of importance, and offer a valid proof for it. The most important gift of this paper i...In this note, we analyze a few major claims about . As a consequence, we rewrite a major theorem, nullify its proof and one remark of importance, and offer a valid proof for it. The most important gift of this paper is probably the reasoning involved in all: We observe that a constant, namely t, has been changed into a variable, and we then tell why such a move could not have been made, we observe the discrepancy between the claimed domain and the actual domain of a supposed function that is created and we then explain why such a function could not, or should not, have been created, along with others.展开更多
In this note, we discuss the definition of the S1-convexity Phenomenon. We first make use of some results we have attained for?? in the past, such as those contained in [1], to refine the definition of the phenomenon....In this note, we discuss the definition of the S1-convexity Phenomenon. We first make use of some results we have attained for?? in the past, such as those contained in [1], to refine the definition of the phenomenon. We then observe that easy counter-examples to the claim extends K0 are found. Finally, we make use of one theorem from [2] and a new theorem that appears to be a supplement to that one to infer that? does not properly extend K0 in both its original and its revised version.展开更多
Partial formalization, which involves the development of deductive connections among statements, can be used to examine assumptions, definitions and related methodologies that are used in science. This approach has be...Partial formalization, which involves the development of deductive connections among statements, can be used to examine assumptions, definitions and related methodologies that are used in science. This approach has been applied to the study of nucleic acids recovered from natural microbial assemblages (NMA) by the use of bulk extraction. Six pools of bulk-extractable nucleic acids (BENA) are suggested to be present in a NMA: (pool 1) inactive microbes (abiotic-limited);(pool 2) inactive microbes (abiotic permissive, biotic-limited);(pool 3) dormant microbes (abiotic permissive, biotic-limited, but can become biotic permissive);(pool 4) in situ active microbes (the microbial community);(pool 5) viruses (virocells/virions/cryptic viral genomes);and (pool 6) extracellular nucleic acids including extracellular DNA (eDNA). Definitions for cells, the microbial community (in situ active cells), the rare biosphere, dormant cells (the microbial seed bank), viruses (virocells/virions/cryptic viral genomic), and diversity are presented, together with methodology suggested to allow their study. The word diversity will require at least 4 definitions, each involving a different methodology. These suggested definitions and methodologies should make it possible to make further advances in bulk extraction-based molecular microbial ecology.展开更多
In general, the definition of the transverse flow can be classified into the slope flow[1] and the average flow[2]in the certain mid-rapidity region. For a given type of isotope with mass number A, these two definitio...In general, the definition of the transverse flow can be classified into the slope flow[1] and the average flow[2]in the certain mid-rapidity region. For a given type of isotope with mass number A, these two definitions are,respectively, expressed展开更多
背景:目前运动疗法是非药物治疗腰痛的有效方法,运动疗法可通过骨骼和肌肉之间的机械-化学偶联维持腰椎的稳定,但目前尚无关于运动疗法通过机械-化学偶联缓解慢性非特异性下背痛之间研究进展及最佳治疗方案的明确阐述。目的:综述运动疗...背景:目前运动疗法是非药物治疗腰痛的有效方法,运动疗法可通过骨骼和肌肉之间的机械-化学偶联维持腰椎的稳定,但目前尚无关于运动疗法通过机械-化学偶联缓解慢性非特异性下背痛之间研究进展及最佳治疗方案的明确阐述。目的:综述运动疗法时椎旁肌通过机械-化学偶联影响腰椎稳定性进而缓解慢性非特异性下背痛的相关研究进展,以及目前运动疗法治疗慢性非特异性下背痛的最佳方案。方法:在万方数据库、中国知网、维普、Web of Science和PubMed数据库进行文献检索,以“慢性非特异性下背痛,腰椎稳定,椎旁肌,运动疗法”为中文检索词,以“chronic nonspecific low back pain,lumbar stabilization,paravertebral muscle,exercise therapy”为英文检索词,检索各数据库建库至2024年1月发表的相关文献,最终纳入93篇文献进行归纳总结。结果与结论:运动疗法可以通过适当的机械刺激作用于椎旁肌和骨骼并使其产生相应的变化。运动疗法主要通过机械-化学偶联方式来提高椎旁肌的质量,进而维持腰椎稳定,从而更好地缓解慢性非特异性下背痛,是慢性非特异性下背痛的重要干预措施。但是,对于运动疗法通过腰椎稳定来治疗慢性非特异性下背痛的确切有效方案尚无明确报道。个体化运动方案的制定对于慢性非特异性下背痛的治疗和预后尤为重要。同一个体的肌肉质量与骨骼质量是密切相关的,影像学评估椎旁肌的质量和体积对于疾病的发现和干预具有重要意义。展开更多
文摘The purpose of the research in the NJIKI’s fundamental THEOREM-DEFINITION on fractions in the mathematical set ℚand by extension in ℝand ℂand in order to construct some algebraic structures is about the proved EXISTENCE and the DEFINITION by NJIKI of two INNOVATIVE, IMPORTANT and TEACHABLE operations of addition or additive operations, in ℚ, marked ⊕and +α,β, and taken as VECTORIAL, TRIANGULAR, of THREE or PROPORTIONAL operations and in order to make THEM not be different from the RATIONAL ONE, +, but to bring much more and new information on fractions, and, by extension in ℝand ℂ. And the very NJIKI’s fundamental THEOREM-DEFINITION having many APPLICATIONS in the everyday life of the HUMAN BEINGS and without talking about computer sciences, henceforth being supplied with very interesting new ALGORITHMS. And as for the work done in the research, it will be waiting for its extension to be done after publication and along with the research results concerned.
文摘Through reviewing domestic and overseas literatures about the definition of urban-rural fringe,it can be found that the combination of qualitative and quantitative definition methods has become a dominant one.This paper makes out the principle and basis,uses the data of villages and towns,and establishes an index system from three angles:population,land use and landscape.And then the gravitational model is applied to define the urban-rural fringe with Beijing as an example.
文摘In nature, to realize the smooth motion for different speeds, the continuous gait transition is usually required for the quadrupeds. Thus, the gait simulation of quadrupeds is a requisite step to obtain the stable and energy-efficient gait for the walking machines. In this paper, the definitions of the two gait parameters, phasic difference and duty factor are presented, which can determine the gait of the quadrupeds. Then, several typical gaits of the quadrupeds are analyzed such that the seven standard gaits and corresponding parameters are summarized. Additionally, the variance law of the two parameters, which determine the relationship of gait transition, is analyzed. Furthermore, the quadruped gait derivative spectrum (QGDS) is proposed and the gait definition of the quadrupeds is presented. To minimize the power consumption, the choice criterion of gait, the optimal gait in terms of the motion speed, duty factory, and power consumption for the walking machines, is developed. Last, the continuous variance of the gait is implemented by the simulation of the gait transition from walk to trot, which evaluate the choice criterion and transition of gait.
文摘A plant-based diet consists of all minimally processedfruits, vegetables, whole grains, legumes, nuts and seeds,herbs, and spices and excludes all animal products, includ-ing red meat, poultry, fish, eggs, and dairy products.
文摘While the incidence of gastric cancer(GC)in general has decreased worldwide in recent decades,the incidence of diffuse cancer historically comprising poorly cohesive cells-GC(PCC-GC)and including signet ring cell cancer is rising.Literature concerning PCC-GC is scarce and unclear,mostly due to a large variety of historically used definitions and classifications.Compared to other histological subtypes of GC,PCC-GC is nevertheless characterized by a distinct set of epidemiological,histological and clinical features which require a specific diagnostic and therapeutic approach.The aim of this review was to provide an update on the definition,classification and therapeutic strategies of PCC-GC.We focus on the updated histological definition of PCC-GC,along with its implications on future treatment strategies and study design.Also,specific considerations in the diagnostic management are discussed.Finally,the impact of some recent developments in the therapeutic management of GC in general such as the recently validated taxane-based regimens(5-Fluorouracil,leucovorin,oxaliplatin and docetaxel),the use of hyperthermic intraperitoneal chemotherapy as well as pressurized intraperitoneal aerosol chemotherapy and targeted therapy have been reviewed in depth for their relative importance for PCC-GC in particular.
基金Supported by Pilot/feasibility Grant from the UNC Center for Gastrointestinal Biology and Disease,NIH P30 DK34987NIH award K23DK090073 (in part)
文摘AIM:To develop and validate a case definition of eosinophilic esophagitis(EoE) in the linked Danish health registries.METHODS:For case definition development,we queried the Danish medical registries from 2006-2007 to identify candidate cases of EoE in Northern Denmark.All International Classification of Diseases-10(ICD-10) and prescription codes were obtained,and archived pathology slides were obtained and re-reviewed to determine case status.We used an iterative process to select inclusion/exclusion codes,refine the case definition,and optimize sensitivity and specificity.We then re-queried the registries from 2008-2009 to yield a validation set.The case definition algorithm was applied,and sensitivity and specificity were calculated.RESULTS:Of the 51 and 49 candidate cases identified in both the development and validation sets,21 and 24 had EoE,respectively.Characteristics of EoE cases in the development set [mean age 35 years;76% male;86% dysphagia;103 eosinophils per high-power field(eos/hpf)] were similar to those in the validation set(mean age 42 years;83% male;67% dysphagia;77 eos/hpf).Re-review of archived slides confirmed that the pathology coding for esophageal eosinophilia was correct in greater than 90% of cases.Two registrybased case algorithms based on pathology,ICD-10,and pharmacy codes were successfully generated in the development set,one that was sensitive(90%) and one that was specific(97%).When these algorithms were applied to the validation set,they remained sensitive(88%) and specific(96%).CONCLUSION:Two registry-based definitions,one highly sensitive and one highly specific,were developed and validated for the linked Danish national health databases,making future population-based studies feasible.
文摘Objectives: We aimed to 1) investigate the prevalence of MS in apparently healthy, non-hypertensive non-diabetic individuals living in Jeddah using the IDF and the NCEP-ATP III criteria to test for agreement in classification, and to determine the characteristics of subjects identified by either definition, and 2) examine the significance of family medical history and life style habits. Methods: 557 apparently healthy individuals aged 18 - 50 y were randomly approached in Jeddah health centres. 412 agreed to participate, while 55 were excluded because they were found to be frankly hypertensive and/or diabetic. Finally, 357 apparently healthy subjects with no hypertension or diabetes were fully studied. Anthropometric and demographic information were collected. Insulin, glucose, and lipid profile were obtained in fasting blood samples. Individuals were identified using the two definitions of metabolic syndrome, and their characteristics were compared statistically to the rest of the population. Results: Of the 233 subjects fulfilling the inclusion criteria, 44 and 39 (18.9% and 16.7%) were identified as having MS by the IDF or ATPIII definitions, respectively. The most common characteristic was central obesity using the IDF definition, and low HDL-cholesterol using the NCEP-ATP III definition. As expected from our exclusion criteria, the least common feature was high blood pressure in both cases. There was no significant difference between subgroups with and without MS with regard to smoking, exercise, and family history of disease. Regression analysis indicated the strongest predictors of MS were: blood glucose, LDL-C/HDL-C ratio and plasma insulin using the NCEP-ATPIII definition, and blood glucose, Waist /Hip ratio and plasma atherogenic index (PAI) using the IDF definition. Conclusions: In the absence of local cut-off thresholds for waist circumference, subjects might escape diagnosis using the IDF definition. The use of waist/Hip ratio, LDL-C: HDL-C, PAI and circulating insulin help with the diagnosis.
文摘In this note, we analyze a few major claims about . As a consequence, we rewrite a major theorem, nullify its proof and one remark of importance, and offer a valid proof for it. The most important gift of this paper is probably the reasoning involved in all: We observe that a constant, namely t, has been changed into a variable, and we then tell why such a move could not have been made, we observe the discrepancy between the claimed domain and the actual domain of a supposed function that is created and we then explain why such a function could not, or should not, have been created, along with others.
文摘In this note, we discuss the definition of the S1-convexity Phenomenon. We first make use of some results we have attained for?? in the past, such as those contained in [1], to refine the definition of the phenomenon. We then observe that easy counter-examples to the claim extends K0 are found. Finally, we make use of one theorem from [2] and a new theorem that appears to be a supplement to that one to infer that? does not properly extend K0 in both its original and its revised version.
文摘Partial formalization, which involves the development of deductive connections among statements, can be used to examine assumptions, definitions and related methodologies that are used in science. This approach has been applied to the study of nucleic acids recovered from natural microbial assemblages (NMA) by the use of bulk extraction. Six pools of bulk-extractable nucleic acids (BENA) are suggested to be present in a NMA: (pool 1) inactive microbes (abiotic-limited);(pool 2) inactive microbes (abiotic permissive, biotic-limited);(pool 3) dormant microbes (abiotic permissive, biotic-limited, but can become biotic permissive);(pool 4) in situ active microbes (the microbial community);(pool 5) viruses (virocells/virions/cryptic viral genomes);and (pool 6) extracellular nucleic acids including extracellular DNA (eDNA). Definitions for cells, the microbial community (in situ active cells), the rare biosphere, dormant cells (the microbial seed bank), viruses (virocells/virions/cryptic viral genomic), and diversity are presented, together with methodology suggested to allow their study. The word diversity will require at least 4 definitions, each involving a different methodology. These suggested definitions and methodologies should make it possible to make further advances in bulk extraction-based molecular microbial ecology.
文摘In general, the definition of the transverse flow can be classified into the slope flow[1] and the average flow[2]in the certain mid-rapidity region. For a given type of isotope with mass number A, these two definitions are,respectively, expressed
文摘背景:目前运动疗法是非药物治疗腰痛的有效方法,运动疗法可通过骨骼和肌肉之间的机械-化学偶联维持腰椎的稳定,但目前尚无关于运动疗法通过机械-化学偶联缓解慢性非特异性下背痛之间研究进展及最佳治疗方案的明确阐述。目的:综述运动疗法时椎旁肌通过机械-化学偶联影响腰椎稳定性进而缓解慢性非特异性下背痛的相关研究进展,以及目前运动疗法治疗慢性非特异性下背痛的最佳方案。方法:在万方数据库、中国知网、维普、Web of Science和PubMed数据库进行文献检索,以“慢性非特异性下背痛,腰椎稳定,椎旁肌,运动疗法”为中文检索词,以“chronic nonspecific low back pain,lumbar stabilization,paravertebral muscle,exercise therapy”为英文检索词,检索各数据库建库至2024年1月发表的相关文献,最终纳入93篇文献进行归纳总结。结果与结论:运动疗法可以通过适当的机械刺激作用于椎旁肌和骨骼并使其产生相应的变化。运动疗法主要通过机械-化学偶联方式来提高椎旁肌的质量,进而维持腰椎稳定,从而更好地缓解慢性非特异性下背痛,是慢性非特异性下背痛的重要干预措施。但是,对于运动疗法通过腰椎稳定来治疗慢性非特异性下背痛的确切有效方案尚无明确报道。个体化运动方案的制定对于慢性非特异性下背痛的治疗和预后尤为重要。同一个体的肌肉质量与骨骼质量是密切相关的,影像学评估椎旁肌的质量和体积对于疾病的发现和干预具有重要意义。
