Impact analysis of supplier relationship on supply chain resilience using biological cellular resilience theory

A supply chain resilience model is established based on the biological cellular resilience theory to analyze the impact of the supplier relationship on supply chain resilience. A scenario where the market demand is changed suddenly by some undesired events is considered. The results reveal that enhancing collaboration with a more resilient supplier can significantly improve supply chain resilience and reduce supply chain losses. It is also found that enhancing the supplier relationship can significantly benefit supply chain resilience if the collaborative intensity is relatively low, and it has less effect if supply chain members have already collaborated closely. Thus, enhancing the supplier relationship to a limited intensity is a relatively effective and economic method to strengthen supply chain resilience.

Relationship between insulin A chain regions and insulin biological activities

AIM To study the relationship between insulinA chain regions and insulin biological activities,we designed a series of insulin analogues withchanges at A21,A12-18 of C-terminal helicalregion and A8-10 Iocated in the region of A6-A11intra-chain disulphide bond.METHODS Insulin A-chain analogues wereprepared by stepwise Fmoc solid-phase manualsynthesis and then combined with natural B-chain of porcine insulin to yield correspondinginsulin analogues.Their biological activitieswere tested by receptor binding,mouseconvulsion and immunological assay.RESULTS[A21Ala]Ins retains 70.3% receptorbinding capacity and 60% in vivo biologicalactivity.[DesA13-14,A21Ala]Ins and[DesA12-13-14-15,A21Ala]Ins still have definite biologicalactivity,7.9% and 4.0% receptor binding,and6.2% and 3.3% in vivo biological activityrespectively.[A15Asn,A17Pro,A21Ala]Insmaintains 10.4% receptor binding and 10% invivo biological activity.[A8His,A9Arg,A10Pro,A21Ala]Ins,[A8His,A9Lys,A10Pro,A21Ala]Insand [A8His,A9Lys,A10Arg,A21Ala]Ins have51.9%,44.3% and 32.1% receptor bindingrespectively,50%,40% and 30% in vivobiological activity respectively,and 28.8%,29.6% and 15.4% immunological activityrespectively. CONCLUSION A21Asn can be replaced bysimple amino acid residues.The A chains withgradually damaged structural integrity in A12-18helical region and the demolition of the A12-18helical region by the substitution of Pro and Asnfor A17Glu and A15Gln respectively can combinewith the B chain and the combination productsshow definite biological activity,the helicalstructure of A12-18 is essential for biologicalactivities of insulin.A8-10 is not muchconcerned with biological activities,but is muchmore important antigenically in binding to itsantibodies,these results may help us design anew type of insulin analogue molecule.

Characteristic of Rare EarthDistribution in Biologic Chains of RE-Rich Back-ground Regions

REE contents of water and vegetables, from two typical RE-rich background regionsand normal region in Gainan,Jiangxi Province, China, indicatethat REE contents are markedlydifferent in water and vegetables.There are average 0.03 mg·L-1and 0. 11 mg·L-1 REE in water ofA and B regions. As REE contentsof vegetables for A region are different from B region, it suggeststhat there are a lot of factors controlling REE distribution betweenvegetables. Comparing with thenormal region, soluble RE contentsin water of the RE-rich backgroundregions are factors of 68 and 18than that of the normal region.REE contents of the most plantsand crops in A and B regions arehigher than that in the normal region. It is clear that REE are theindispensable elements of plantsduring their growing period. Asthere are unusually higher REEcontents of some plants in A and Bthan in the normal regions, it isconsidered to result from absorbingREE passively during the period ofplants and crops growing up.

THE FLUX OF CHEMICAL MUTAGENS THROUGH AN EXPERIMENTAL MARINE FOOD CHAIN AND THEIR GENOTOXICITY Ⅰ. INORGANIC MUTAGEN-CADMIUM (Ⅱ)TRANSFER OF CADMIUM FROM PHAEODACTYLUM TRICORNUTUM TO PENAEUS ORIENTALIS AND TO HEXAGRAMMOS OTAKII

In order to investigate flux of cadmium,the chemicalmutagen through 3-trophic level marine food chains and the harmit might do to human health,we deviced a phytoplankton based experimental marine food chain (from Phaeodactylum tricornutumBohlin to the prawn Penaeus orientalis Kishinouye,and to thefish Hexagrammos otakii Jordan et Starks) and studied its

Brief Analysis of Characteristics and Further Research Orientation of Bioenergy Supply Chain

Because of the pressure in environmental protection and the less amount of conventional energy, more and more countries around the world attached great importance to the development and utilization of bioenergy. Using bioenergy effectively and setting up a perfect bioenergy industry chain are the premises for bioenergy to be well developed. The main applications of bioenergy in China are electric power generating and fuel refining. But there is still some gap between Chinaand other countries in bioenergy’s development, not only in the technology, but also in government policy support. First of all, this paper briefly introduces the concept and the basic condition, the development and utilization of bioenergy inChina. Secondly, this paper makes an analysis and comparison of supply chain for the biomass and coal. Finally, this paper gives some suggestions to the further research orientation of the biomass supply chain based on its characteristics.

Clinical Value of Molecular Biological Methods in Respiratory Tuberculosis in Children

The pattern of clinical forms of respiratory tuberculosis in children shows a preponderance of intrathoracic lymph node tuberculosis （89.4%） that is characterized by a complicated process in every third child under present-day conditions. Positive result of PCR closely correlates with the severity and extent of the specific process in children. Real-time PCR （RT-PCR） was ascertain to exhibit the highest sensitivity in detecting Mycobacterium tuberculosis DNA in children with primary generalized tuberculosis （62.5%） and in those with a disseminated specific process （55.6%）, which was much higher than conventional bacteriological study of diagnostic materials. By taking into account the findings, the RT-PCR detection of M. tuberculosis was considered as a substantial criterion for evaluating the magnitude of specific changes and the degree of tuberculosis infection activity in children.

Greening the Supply Chain: Drivers and Outcomes in the Korean Manufacturing Industry

This research investigates the determinants of green supply chain management(GSCM)adoption and its impact on organizational performance,while considering the potential moderating factors influencing GSCM adoption.Despite the growing prevalence of GSCM practices among Korean firms,the factors driving their adoption have not received sufficient attention.To bridge this gap,the study uses structural equation modeling,integrating stakeholder theory and resource-based theory to explore how green entrepreneurial orientation(GEO),institutional pressure,and relational capital affect GSCM adoption.Additionally,the study explores the effects of GSCM implementation on competi­tiveness and economic performance.Drawing data from a sample of 213 Korean manufacturing firms,the PLS-SEM analysis highlights the significant influence of GEO,institutional pressure,and relational capital on GSCM adoption.Additionally,the study emphasizes the positive impact of GSCM implementation on firm competitiveness.These find­ings provide valuable insights for enhancing sustainability in supply chain management and are applicable to similar context countries such as Taiwan,China,Japan,and the Netherlands.

研究性教学模式在地方高校生物科学专业人才培养中的应用研究

研究性教学强调将研究和教学相结合,通过研究项目、实践活动等方式培养学生的研究能力和创新思维。研究性教学是提升人才培养质量的重要途径,地方高校创新性应用型人才的培养改革势在必行。为更好提升地方高校学生创新和研究能力及教师教学水平,以南阳师范学院生物科学专业为例,探究新形势下在“平衡”教学与科研的同时,从以人为本因材施教、需求导向服务地方、提升研究性教学能力推动教学改革、完善奖励激励机制等方面构建生物科学专业研究性教学模式,为提升人才培养质量奠定基础,以更好地服务社会发展和地方经济。

无寄生运动3-DOF 2T1R并联机构拓扑设计与分析

为充分研究少自由度并联机构所具备优势,拓宽其应用领域,设计并研究一种含冗余支链且无寄生运动三自由度两平移一转动(2T1R)并联机构,完成运动学和动力学分析。基于方位特征集(POC)的拓扑机构学理论方法,设计了一种含冗余支链且无寄生运动的两平移一转动并联机构,并进行拓扑分析,结果表明:该机构还具有部分运动解耦特性;根据基于拓扑特征运动学的建模方法,求得机构位置正反符号解;又基于位置反解分析了机构奇异性,基于位置正解给出了工作空间;基于虚功原理的序单开链法对机构进行动力学建模,求得了该机构移动副处的驱动力以及两个子运动链(SKC)连接处的支反力;概念设计了该机构的一种应用场景。

质量基础设施服务平台研究与实践经验分享

本文以湖北省市场监管局整合“基础性服务、拓展性服务、融合性服务、政务性服务”四类资源构建“一站式”质量基础设施服务平台为实际应用案例进行研究,采用面向需求导向的方法,厘清企业、服务站、技术机构和市场监管部门的逻辑关系,梳理一站式平台的定位,助企纾困,为企业提供“零距离”的“一站式”质量基础设施服务,进一步拓展质量技术资源服务一张网的建设。提出基于价值链方法,分阶段有序构建“一站式”服务平台,线上线下一体化运营,监管与服务融合发展,统筹推进“智慧服务一张网”建设,解决中小企业质量服务“三难找”、质量技术机构“小散弱”等问题,助力中小企业提质增效,促进国内外大循环健康有序发展。

可吸收载抗菌药物硫酸钙与生物骨水泥链珠膜诱导在儿童足跟组织缺损合并创伤性跟骨骨髓炎中的效果比较

目的:探讨可吸收载抗菌药物硫酸钙与生物骨水泥链珠膜诱导在儿童足跟组织缺损合并创伤性跟骨骨髓炎中的效果。方法:选取2018年1月~2022年12月期间某院收治的96例儿童足跟组织缺损合并创伤性跟骨骨髓炎患儿作为研究对象,根据手术方式不同分为对照组(n=54)和观察组(n=42)。对照组患儿采用合理皮瓣修复后联合生物骨水泥链珠膜诱导治疗,观察组患儿采用合理皮瓣修复后联合可吸收载抗菌药物硫酸钙治疗。比较两组患儿创面分泌物细菌培养、感染性指标[肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)、白介素-8(IL-8)、白细胞计数(WBC)、红细胞沉降率(ESR)]、视觉模拟评分法(VAS)评分、住院时间、愈合时间、并发症、感染复发率及对照组患儿再次手术情况。结果:两组患儿创面分泌物细菌培养结果提示,均以金黄色葡萄球菌为主。术后7天、14天,两组患儿WBC、ESR、IL-6、IL-8、TNF-α均降低(P<0.05),且观察组低于对照组(P<0.05)。术后1、3个和6个月,两组患儿VAS评分均降低(P<0.05),观察组患儿术后1、3个月VAS评分低于对照组(P<0.05),两组患儿术后6个月VAS评分比较无统计学差异(P>0.05)。观察组患儿住院、愈合时间均短于对照组(P<0.05)。两组患儿并发症总发生率、术后6个月感染复发率比较均无统计学差异(P>0.05)。对照组患儿均需要再次手术取出骨水泥链珠,其中9例患儿再次接受骨水泥植入。结论:合理皮瓣修复后联合可吸收载抗菌药物硫酸钙治疗可更有效减轻患儿疼痛,抑制炎症反应,促进术后康复和骨愈合。

RCEP背景下强化对外贸易产业链合作的路径——以中韩(盐城)产业园为例

RCEP的签订有利于区域一体化发展,形成更加稳定的产业链、供应链,为出口、投资打开更大空间。盐城与韩国隔海相望,是对韩贸易重要口岸,加强对韩贸易产业链合作,将对盐城“走出去,请进来”发展形成长远性利好。为积极应对RCEP带来的挑战,梳理了RCEP背景下盐城对外贸易产业链合作优势,分析了中韩贸易变动趋势;借鉴上海、深圳、合肥等地贸易产业链合作的经验启示,提出要以产业链思维形成产业集聚和规模效应、数字化思维发挥平台集聚要素和引导流量能力、趋势性思维开展碳汇产业精准招商,以及专业化思维完善基础设施布局建设等对策。

短链脂肪酸的生物学功能研究进展

短链脂肪酸(SCFAs)指碳链上碳原子数在1~6之间的一类饱和有机酸。本文全面阐述了SCFAs的来源,重点关注SCFAs的生物学功能研究进展,归纳了SCFAs对机体供能、维持肠道和神经系统健康、降低血压以及预防肥胖方面的作用机制,为后续SCFAs在营养学领域的研究与应用提供理论依据。

生物导向型预备技术在口腔修复中的应用

口腔修复中的牙体预备边缘一直是口腔医生关注的热点问题,不当的预备边缘可能导致龋病和牙周炎等疾病,最终导致修复失败。生物导向型预备技术的应用已证明可恢复良好的牙周软硬组织形态,有望替代传统牙体预备方法。从生物导向型预备技术在贴面、全冠、种植中的应用综合论述生物导向型预备技术在口腔修复中的应用。

共同富裕的农业供应链治理:理论建构与实践路径

党的二十大提出,中国式现代化是全体人民共同富裕的现代化。在共同富裕的背景下,农业供应链不仅要加速“延链、补链、壮链、强链”、拓展产业的增值优势,也要不断发挥对乡村发展的积极作用,促进乡村振兴。乡村振兴是实现共同富裕的必然要求,而农业供应链与乡村社区的整合是共同富裕的农业供应链治理的核心。然而,农业供应链是以消费者需求为导向,以提高农产品生产、加工、物流、销售等环节的质量和效率为目标,并不能确保乡村社区发展和社会公平;共同富裕的理念,迫切需要二者超越发展目标的错位,促进实践过程的整合。为了促进农业供应链治理与乡村发展协同推进,采用概念建构的研究方式,基于农业供应链与乡村社区的多元关系,提炼出“交易逻辑”和“革新逻辑”两种互动模式,形成财富导向和社区导向的农业供应链治理框架。这不仅有助于促进农业供应链与乡村发展良性互动,也为农业产业驱动的乡村振兴提供了理论和实践指导,推动共同富裕的农业现代化。

“学、思、测、用、评”互嵌的《信号与系统》教学设计与实践

从新工科人才需求出发,以专业、课情、学情特点为依据,基于OBE理念对《信号与系统》进行了宏观和微观教学设计。在宏观上,以实现知识传授、能力培养、价值塑造为目标,设计教学目标、教学内容、教学活动与考核反馈等教学环节。在微观上,进行知识点精分,以“问题牵引”为主要手段,“学、思、测、用、评”教学活动相互内嵌,融入工程能力的培养。通过教学实践证明,该教学方法可以为教学活动提供弹性伸缩空间,更加有利于因材施教,提升学习效果。

Control Study of Parasitic Pyemotes sp.against Oriental Fruit Moth(Grapholitha molesta Bussck)

[ Objective] The paper was to study the parasitic ability and field control effect of Pyemotes sp. against oriental fruit moth （Grapholitha molesta Bussck） which caused damage on Photinia. [ Method] The indoor infection test and field control test of Pyemotes sp. against oriental fruit moth was carried out. The parasitic ability and activity characteristic of Pyemotes sp. were observed, and the effect of environmental factors such as humidity and temperature on the para- sitic ability of Pyemotes sp. was studied. [Result] Pyemotes sp. had good control effect on oriental fruit moth under the proper conditions; the host searching abili- ties of Pyemotes sp. were different at different temperature and humidity conditions, humidity had large impact on the activity of Pyemotes sp., while temperature had large impact on the individual activity. [ Conclusion] The result showed that Pyemotes sp. had effective control effort on oriental fruit moth.

创新链视角下应用型高校科研发展路径探析

[研究目的]寻求适应自身的科研发展路径,是当前应用型高校面临的重要问题。基于正向线性创新链模式和反向反馈线性创新链模式的视角,提出应用型高校科研发展的两种路径。[研究方法]第一,适用于非行业背景类应用型高校的“衔接基础研究和市场需求,聚焦原创成果的应用转化”科研发展路径,即树立促进基础科研成果应用转化的科研定位;强化与重点高校和科研院所合作,承接基础科研成果的转化;深入了解行业和地方需求,明确原创成果转化的应用方向;强化学校科技创新能力,提升服务外部需求的水平。第二,适用于行业背景类应用型高校的“紧跟行业最新动态,瞄准关键技术研发”科研发展路径,即树立服务行业企业发展的科研定位;加强与行业企业之间的全方位联系;围绕服务行业发展凝聚学校资源。[研究结论]上述两种科研发展路径有利于提升应用型高校办学水平,推动应用型高校建设顺利进行。

工业互联视域下制造业服务化转型组态新路径研究

随着工业互联网的发展,制造业正在逐步从传统的产品制造模式向以服务为导向的新型模式转变。从沪深A股上市制造企业面板中选取60家制造企业作为研究对象,运用模糊集质性比较分析(fsQCA)方法,从制造业价值链中“研发—制造—供应链”视角深入挖掘不同条件下的服务化转型路径。研究发现:数字金融是制造业服务化转型的必要条件;制造业服务化转型不是简单的单因素因果关系,其受到多重因素协同并发影响;形成制造业服务化创新共有5条路径,被分为3种类型,分别是科技成果转化服务型、数字贸易服务型、产品服务型。研究从多维视角分析制造企业转型的驱动机制,丰富了服务化相关研究,并为企业的服务化发展提供建议。

全产业链导向渐进式复合应用型人才培养体系研究——以网络信息安全产业为例

作为正在蓬勃发展的朝阳产业,我国网络信息安全产业总体人才缺乏,但也存在人才供需失衡的问题。目前高校的人才培养课程设置要么来自于学科研究的驱动,要么偏向于较窄的热门就业岗位的需求,不能满足产业各方面的人才需求,也不利于信息安全毕业生的长远职业发展。该文从信息安全全产业链的视角出发,在剖析目前的各类信息安全人才培养方案的基础上,提出新的信息安全复合应用型人才培养方案,为网络信息安全产业培养所需的各类人才提供新的参考解决方案。