Gastropods,a mollusk class including slugs and snails,represent an extraordinarily diverse and ecologically significant group of organisms featuring the largest class of invertebrates.They can be classified as aquatic...Gastropods,a mollusk class including slugs and snails,represent an extraordinarily diverse and ecologically significant group of organisms featuring the largest class of invertebrates.They can be classified as aquatic and terrestrial animals having coiled shells,although some species have reduced or absent shells.Their unique body structure includes a muscular foot for locomotion,a visceral mass containing essential organs,and a distinct head region with sensory organs such as tentacles and eyes.They are used to secrete a complex mixture of glycoproteins,enzymes,peptides,mucus and other bioactive compounds,namely slime,which represents a tool to allow locomotion,protection,and interaction within different habitats.The biological activities of the slime have attracted considerable interest due to their diverse and potentially valuable properties ranging from defense mechanisms to potential therapeutic applications in wound healing,antimicrobial therapy,management of inflammation,and neurological disorders.This review aims at exploring the beneficial effects of snail and slug slime focusing,in particular,on the improvement of the biological processes underlying them.Continued exploration of the intricate components of these slimy secretions promises to discover new bioactive molecules with diverse applications in various scientific and industrial fields.展开更多
Gas-liquid-liquid three-phase slug flow was generated in both hydrophilic and hydrophobic microreactors with double T-junctions.The bubble-droplet relative movement and the local mass transfer within the continuous sl...Gas-liquid-liquid three-phase slug flow was generated in both hydrophilic and hydrophobic microreactors with double T-junctions.The bubble-droplet relative movement and the local mass transfer within the continuous slug and the dispersed droplet were investigated.It was found that bubbles moved faster than droplets under low capillary number(Ca),while droplets moved faster upon the increase of Ca due to the increased inertia.For the first time,we observed that the increased viscosity of droplets fastened the droplet movement.The mass transfer in the continuous slug was dominated by convection,leading to nearly constant global mass transfer coefficient(k_(L)a);while that in the dispersed droplet was dominated by diffusion,resulting in k_(L) decreasing along the channel.Such features are analogical to the corresponding gas-liquid or liquid-liquid two-phase slug flow,but the formation of bubble-droplet clusters caused by relative movement lowered the absolute mass transfer coefficient.These results provide insights for the precise manipulation of gas-liquid-liquid slug flow in microreactors towards process optimization.展开更多
基金FAR 2020,2021 Cataldi,FAR 2020,2021 Zara and also supported by MUR National Innovation Ecosystem-Recovery and Resilience Plan(PNRR)Italy。
文摘Gastropods,a mollusk class including slugs and snails,represent an extraordinarily diverse and ecologically significant group of organisms featuring the largest class of invertebrates.They can be classified as aquatic and terrestrial animals having coiled shells,although some species have reduced or absent shells.Their unique body structure includes a muscular foot for locomotion,a visceral mass containing essential organs,and a distinct head region with sensory organs such as tentacles and eyes.They are used to secrete a complex mixture of glycoproteins,enzymes,peptides,mucus and other bioactive compounds,namely slime,which represents a tool to allow locomotion,protection,and interaction within different habitats.The biological activities of the slime have attracted considerable interest due to their diverse and potentially valuable properties ranging from defense mechanisms to potential therapeutic applications in wound healing,antimicrobial therapy,management of inflammation,and neurological disorders.This review aims at exploring the beneficial effects of snail and slug slime focusing,in particular,on the improvement of the biological processes underlying them.Continued exploration of the intricate components of these slimy secretions promises to discover new bioactive molecules with diverse applications in various scientific and industrial fields.
基金the financial support for this work from National Natural Science Foundation of China(21991103,92034303,91634204)。
文摘Gas-liquid-liquid three-phase slug flow was generated in both hydrophilic and hydrophobic microreactors with double T-junctions.The bubble-droplet relative movement and the local mass transfer within the continuous slug and the dispersed droplet were investigated.It was found that bubbles moved faster than droplets under low capillary number(Ca),while droplets moved faster upon the increase of Ca due to the increased inertia.For the first time,we observed that the increased viscosity of droplets fastened the droplet movement.The mass transfer in the continuous slug was dominated by convection,leading to nearly constant global mass transfer coefficient(k_(L)a);while that in the dispersed droplet was dominated by diffusion,resulting in k_(L) decreasing along the channel.Such features are analogical to the corresponding gas-liquid or liquid-liquid two-phase slug flow,but the formation of bubble-droplet clusters caused by relative movement lowered the absolute mass transfer coefficient.These results provide insights for the precise manipulation of gas-liquid-liquid slug flow in microreactors towards process optimization.
