Jetting-based bioprinting:process,dispense physics,and applications

Jetting-based bioprinting facilitates contactless drop-on-demand deposition of subnanoliter droplets at well-defined positions to control the spatial arrangement of cells,growth factors,drugs,and biomaterials in a highly automated layer-by-layer fabrication approach.Due to its immense versatility,jetting-based bioprinting has been used for various applications,including tissue engineering and regenerative medicine,wound healing,and drug development.A lack of in-depth understanding exists in the processes that occur during jetting-based bioprinting.This review paper will comprehensively discuss the physical considerations for bioinks and printing conditions used in jetting-based bioprinting.We first present an overview of different jetting-based bioprinting techniques such as inkjet bioprinting,laser-induced forward transfer bioprinting,electrohydrodynamic jet bioprinting,acoustic bioprinting and microvalve bioprinting.Next,we provide an in-depth discussion of various considerations for bioink formulation relating to cell deposition,print chamber design,droplet formation and droplet impact.Finally,we highlight recent accomplishments in jetting-based bioprinting.We present the advantages and challenges of each method,discuss considerations relating to cell viability and protein stability,and conclude by providing insights into future directions of jetting-based bioprinting.

A novel encoding mechanism for particle physics

This study proposes a novel particle encoding mechanism that seamlessly incorporates the quantum properties of particles,with a specific emphasis on constituent quarks.The primary objective of this mechanism is to facilitate the digital registration and identification of a wide range of particle information.Its design ensures easy integration with different event generators and digital simulations commonly used in high-energy experiments.Moreover,this innovative framework can be easily expanded to encode complex multi-quark states comprising up to nine valence quarks and accommodating an angular momentum of up to 99/2.This versatility and scalability make it a valuable tool.

Exploring device physics of perovskite solar cell via machine learning with limited samples

Perovskite solar cells(PsCs)have developed tremendously over the past decade.However,the key factors influencing the power conversion efficiency(PCE)of PSCs remain incompletely understood,due to the complexity and coupling of these structural and compositional parameters.In this research,we demon-strate an effective approach to optimize PSCs performance via machine learning(ML).To address chal-lenges posed by limited samples,we propose a feature mask(FM)method,which augments training samples through feature transformation rather than synthetic data.Using this approach,squeeze-and-excitation residual network(SEResNet)model achieves an accuracy with a root-mean-square-error(RMSE)of 0.833%and a Pearson's correlation coefficient(r)of 0.980.Furthermore,we employ the permu-tation importance(PI)algorithm to investigate key features for PCE.Subsequently,we predict PCE through high-throughput screenings,in which we study the relationship between PCE and chemical com-positions.After that,we conduct experiments to validate the consistency between predicted results by ML and experimental results.In this work,ML demonstrates the capability to predict device performance,extract key parameters from complex systems,and accelerate the transition from laboratory findings to commercialapplications.

Transient Thermal Distribution in a Wavy Fin Using Finite Difference Approximation Based Physics Informed Neural Network

Heat transport has been significantly enhanced by the widespread usage of extended surfaces in various engi-neering domains.Gas turbine blade cooling,refrigeration,and electronic equipment cooling are a few prevalent applications.Thus,the thermal analysis of extended surfaces has been the subject of a significant assessment by researchers.Motivated by this,the present study describes the unsteady thermal dispersal phenomena in a wavy fin with the presence of convection heat transmission.This analysis also emphasizes a novel mathematical model in accordance with transient thermal change in a wavy profiled fin resulting from convection using the finite difference method(FDM)and physics informed neural network(PINN).The time and space-dependent governing partial differential equation(PDE)for the suggested heat problem has been translated into a dimensionless form using the relevant dimensionless terms.The graph depicts the effect of thermal parameters on the fin’s thermal profile.The temperature dispersion in the fin decreases as the dimensionless convection-conduction variable rises.The heat dispersion in the fin is decreased by increasing the aspect ratio,whereas the reverse behavior is seen with the time change.Furthermore,FDM-PINN results are validated against the outcomes of the FDM.

Ultrafast photoemission electron microscopy:A multidimensional probe of nonequilibrium physics

Exploring the realms of physics that extend beyond thermal equilibrium has emerged as a crucial branch of condensed matter physics research.It aims to unravel the intricate processes involving the excitations,interactions,and annihilations of quasi-and many-body particles,and ultimately to achieve the manipulation and engineering of exotic non-equilibrium quantum phases on the ultrasmall and ultrafast spatiotemporal scales.Given the inherent complexities arising from many-body dynamics,it therefore seeks a technique that has efficient and diverse detection degrees of freedom to study the underlying physics.By combining high-power femtosecond lasers with real-or momentum-space photoemission electron microscopy(PEEM),imaging excited state phenomena from multiple perspectives,including time,real space,energy,momentum,and spin,can be conveniently achieved,making it a unique technique in studying physics out of equilibrium.In this context,we overview the working principle and technical advances of the PEEM apparatus and the related laser systems,and survey key excited-state phenomena probed through this surface-sensitive methodology,including the ultrafast dynamics of electrons,excitons,plasmons,spins,etc.,in materials ranging from bulk and nano-structured metals and semiconductors to low-dimensional quantum materials.Through this review,one can further envision that time-resolved PEEM will open new avenues for investigating a variety of classical and quantum phenomena in a multidimensional parameter space,offering unprecedented and comprehensive insights into important questions in the field of condensed matter physics.

Physics-based seismic analysis of ancient wood structure:fault-to-structure simulation

Based on the domain reduction method,this study employs an SEM-FEM hybrid workflow which integrates the advantages of the spectral element method(SEM)for flexible and highly efficient simulation of seismic wave propagation in a three-dimensional(3D)regional-scale geophysics model and the finite element method(FEM)for fine simulation of structural response including soil-structure interaction,and performs a physics-based simulation from initial fault rupture on an ancient wood structure.After verification of the hybrid workflow,a large-scale model of an ancient wood structure in the Beijing area,The Tower of Buddhist Incense,is established and its responses under the 1665 Tongxian earthquake and the 1730 Yiheyuan earthquake are simulated.The results from the simulated ground motion and seismic response of the wood structure under the two earthquakes demonstrate that this hybrid workflow can be employed to efficiently provide insight into the relationships between geophysical parameters and the structural response,and is of great significance toward accurate input for seismic simulation of structures under specific site and fault conditions.

Physics-Based Active Learning for Design Space Exploration and Surrogate Construction for Multiparametric Optimization

The sampling of the training data is a bottleneck in the development of artificial intelligence(AI)models due to the processing of huge amounts of data or to the difficulty of access to the data in industrial practices.Active learning(AL)approaches are useful in such a context since they maximize the performance of the trained model while minimizing the number of training samples.Such smart sampling methodologies iteratively sample the points that should be labeled and added to the training set based on their informativeness and pertinence.To judge the relevance of a data instance,query rules are defined.In this paper,we propose an AL methodology based on a physics-based query rule.Given some industrial objectives from the physical process where the AI model is implied in,the physics-based AL approach iteratively converges to the data instances fulfilling those objectives while sampling training points.Therefore,the trained surrogate model is accurate where the potentially interesting data instances from the industrial point of view are,while coarse everywhere else where the data instances are of no interest in the industrial context studied.

3D rock physics template-based probabilistic estimation of tight sandstone reservoir properties

Quantitative prediction of reservoir properties(e.g., gas saturation, porosity, and shale content) of tight reservoirs is of great significance for resource evaluation and well placements. However, the complex pore structures, poor pore connectivity, and uneven fluid distribution of tight sandstone reservoirs make the correlation between reservoir parameters and elastic properties more complicated and thus pose a major challenge in seismic reservoir characterization. We have developed a partially connected double porosity model to calculate elastic properties by considering the pore structure and connectivity, and to analyze these factors' influences on the elastic behaviors of tight sandstone reservoirs. The modeling results suggest that the bulk modulus is likely to be affected by the pore connectivity coefficient, while the shear modulus is sensitive to the volumetric fraction of stiff pores. By comparing the model predictions with the acoustic measurements of the dry and saturated quartz sandstone samples, the volumetric fraction of stiff pores and the pore connectivity coefficient can be determined. Based on the calibrated model, we have constructed a 3D rock physics template that accounts for the reservoir properties' impacts on the P-wave impedance, S-wave impedance, and density. The template combined with Bayesian inverse theory is used to quantify gas saturation, porosity, clay content, and their corresponding uncertainties from elastic parameters. The application of well-log and seismic data demonstrates that our 3D rock physics template-based probabilistic inversion approach performs well in predicting the spatial distribution of high-quality tight sandstone reservoirs in southwestern China.

基于Interactive Physics的物理习题教学--以2023年高考全国乙卷25题和湖北卷15题为例

在传统高中物理教学中,多过程碰撞的物理过程很难在板书上展现出来,成为教学的一大难点。基于Interactive Physics仿真功能,以2023年高考全国乙卷25题和湖北卷15题为例,将多过程碰撞的物理过程可视化,直观展现物理模型,帮助学生理解题目的复杂情境,有效缩短学习时间,提高教学质量和教学效率,实现最优化的教学目标。

Tensile Shock Physics in Compressible Thermoviscoelastic Solid Medium

This paper addresses tensile shock physics in thermoviscoelastic (TVE) solids without memory. The mathematical model is derived using conservation and balance laws (CBL) of classical continuum mechanics (CCM), incorporating the contravariant second Piola-Kirchhoff stress tensor, the covariant Green’s strain tensor, and its rates up to order n. This mathematical model permits the study of finite deformation and finite strain compressible deformation physics with an ordered rate dissipation mechanism. Constitutive theories are derived using conjugate pairs in entropy inequality and the representation theorem. The resulting mathematical model is both thermodynamically and mathematically consistent and has closure. The solution of the initial value problems (IVPs) describing evolutions is obtained using a variationally consistent space-time coupled finite element method, derived using space-time residual functional in which the local approximations are in hpk higher-order scalar product spaces. This permits accurate description problem physics over the discretization and also permits precise a posteriori computation of the space-time residual functional, an accurate measure of the accuracy of the computed solution. Model problem studies are presented to demonstrate tensile shock formation, propagation, reflection, and interaction. A unique feature of this research is that tensile shocks can only exist in solid matter, as their existence requires a medium to be elastic (presence of strain), which is only possible in a solid medium. In tensile shock physics, a decrease in the density of the medium caused by tensile waves leads to shock formation ahead of the wave. In contrast, in compressive shocks, an increase in density and the corresponding compressive waves result in the formation of compression shocks behind of the wave. Although these are two similar phenomena, they are inherently different in nature. To our knowledge, this work has not been reported in the published literature.

New Approaches of Theoretical Astrophysics for Application to Some Astronomical Objects: I. An Application of Non-Classical Equation Mathematical Physics to the Magneto-Hydrodynamic Equilibrium (in Case of Mixed Magnetic Field) of Magnetic Stars

In this paper, we consider the application of the equation of non-classical mathematical physics to magneto-hydrodynamic equilibrium (in the case of a mixed magnetic field) for magnetic stars. First, we give the necessary concepts about the equation of non-classical mathematical physics and the possibility of their applicability to astrophysical problems. The conditions of magneto-hydrodynamic equilibrium are determinate, and self-consistence provides the means to derive the corresponding partial differential equations describing this equilibrium in a magnetosphere magnetic star. Namely, this process is to the non-classical equations of mathematical physics in cases of types. Keldysh-Tricomi, a common case equation of non-classical type, is at first introduced by the author. Using the two main physical efficiencies of MHD. A mathematical model of a poloidal-toroidal mixed magnetic field for magnetic stars is constructed, and this model is classified with respect to degenerating case equations. According to Hopf’s theorem, Maxwell’s equation and the magnetic force balance equation constructed equilibrium conditions of the poloidal-toroidal of the magnetic field for a magnetic star. At the same time, the taken example, which is the self-consistency of this model by observation dates, is investigated. At first, in an application, the method of straight lines for recurrent formulas of calculation of magnetic flux and stream functions is used. The physical means, the corresponding singular point of the sonic line, cutoff, and resonance phenomena are considered. In this case, a general solution equation is found, which is interpreted by this phenomenon as a cutoff, resonance. Finally, this obtained solution gives the conditions of magneto-hydrodynamic equilibrium on the magnetosphere of magnetic stars. Methodology and obtained equations are new approaches that are at first considered.

Design and Research of an Intelligent Learning System for University Physics

In order to break through the limitations of traditional teaching,realize the integration of online and offline teaching,and optimize the intelligent learning experience of university physics,this paper proposes the design of an intelligent learning system for university physics based on cloud computing platforms,and applies this system to teaching environment of university physics.It successfully integrates emerging technologies such as cloud computing,machine learning,and situational awareness,integrates learning context awareness,intelligent recording and broadcasting,resource sharing,learning performance prediction,and content planning and recommendation,and comprehensively improves the quality of university physics teaching.It can optimize the teaching process and deepen intelligent teaching reform,aiming at providing references for the teaching practice of university physics.

Reform and Practice of University Physics Experimental Teaching Based on OBE Concept

Aiming at the problems of unclear teaching objectives,obsolete content,and single method in the experimental teaching of university physics at our university,we have implemented a series of reform initiatives.It mainly includes clarifying the student-centered teaching objectives,optimizing the experimental content,innovating the teaching methods,improving the assessment and evaluation system,and improving the experimental conditions[1,2].After the implementation of the reform,the learning effectiveness of students has been significantly improved,the teaching level of teachers has been significantly enhanced,the curriculum system has been optimized,the efficiency of teaching management has been enhanced,and social recognition has been strengthened.Practice shows that the teaching reform based on the outcome-based education concept effectively improves the quality of university physics experimental teaching and lays the foundation for cultivating innovative talents.

Integration of Ideological and Political Education in College Physics Courses Under the Reform of Smart Teaching

The development of the times has prompted China to enhance the quality of education and the value of talent.As guides for students,teachers should conscientiously implement ideological and political education,create college physics courses that are more in line with modern talent cultivation,eliminate the fixed and singular nature of traditional teaching,and find the integration points of ideological and political education.Teachers need to use the textbook itself,the expansion of resources in smart classrooms,and current technological progress to implement ideological and political education in order to cultivate more high-quality and high-level comprehensive talents for society.

Physical rehabilitation for sensorineural hearing loss in childhood:Progress and challenges

Early intervention for sensorineural hearing loss(SNHL)in childhood is crucial for auditory and language development.In recent years,innovative auditory stimulation techniques and speech therapy strategies,such as middle ear implants,cochlear implants,auditory brainstem implants,and midbrain implants,have provided new avenues for improving patient outcomes.Additionally,basic research advancements in cell reprogramming and regeneration,stem cell therapy,and targeted drug delivery offer promising approaches to meet the individualized needs of children with SNHL.However,many challenges and unresolved issues remain in the treatment of SNHL.This article comments on the case report,which describes a female pediatric patient with SNHL who underwent foot reflexology which led to the normalization of hearing thresholds.Reflexology is considered to have potential benefits in physical rehabilitation,but its efficacy in hearing restoration requires further scientific validation through rigorous clinical trials and large-scale prospective studies.

Integration of wearable electronics and heart rate variability for human physical and mental well-being assessment

Heart rate variability(HRV)that can reflect the dynamic balance between the sympathetic nervous and parasympathetic nervous of human autonomic nervous system(ANS)has attracted considerable attention.However,traditional electrocardiogram(ECG)devices for HRV analysis are bulky,and hard wires are needed to attach measuring electrodes to the chest,resulting in the poor wearable experience during the long-term measurement.Compared with that,wearable electronics enabling continuously cardiac signals monitoring and HRV assessment provide a desirable and promising approach for helping subjects determine sleeping issues,cardiovascular diseases,or other threats to physical and mental well-being.Until now,significant progress and advances have been achieved in wearable electronics for HRV monitoring and applications for predicting human physical and mental well-being.In this review,the latest progress in the integration of wearable electronics and HRV analysis as well as practical applications in assessment of human physical and mental health are included.The commonly used methods and physiological signals for HRV analysis are briefly summarized.Furthermore,we highlighted the research on wearable electronics concerning HRV assessment and diverse applications such as stress estimation,drowsiness detection,etc.Lastly,the current limitations of the integrated wearable HRV system are concluded,and possible solutions in such a research direction are outlined.

Rock physics modeling of heterogeneous carbonatereservoirs： porosity estimation and hydrocarbon detection

In heterogeneous natural gas reservoirs, gas is generally present as small patchlike pockets embedded in the water-saturated host matrix. This type of heterogeneity, also called "patchy saturation", causes significant seismic velocity dispersion and attenuation. To establish the relation between seismic response and type of fluids, we designed a rock physics model for carbonates. First, we performed CT scanning and analysis of the fluid distribution in the partially saturated rocks. Then, we predicted the quantitative relation between the wave response at different frequency ranges and the basic lithological properties and pore fluids. A rock physics template was constructed based on thin section analysis of pore structures and seismic inversion. This approach was applied to the limestone gas reservoirs of the right bank block of the Amu Darya River. Based on poststack wave impedance and prestack elastic parameter inversions, the seismic data were used to estimate rock porosity and gas saturation. The model results were in good agreement with the production regime of the wells.

Studies of Soil Physical Property on Different Abandoned Lands in the Minqin Oasis,Downstream of the Shiyang River

The vast area of farmland was abandoned at downstream of the Shiyang River because of decreased water recourse. To ensure the ecological safety of Minqin Oasis and to provide management basis for the abandoned land, soil physical properties were observed and studied. The authors analyzed land with abandonment time of 1 year, 2 years, 3 years, 4 years, 5 years, 8 years, 15 years, 24 years and 31 years. Samples were took at the 0-40 cm layer of soil to measure the bulk density, porosity and grain composition of soil in the different abandoned lands. Results showed that the tendency of clay content was decreasing, conversely, the fine sand increased at the layer of 0-10 cm of different abandoned lands.The changes of grain content reached a peak at the fourth year after the land was abandoned, then varied slightly. The variation of grain content of abandoned land was obvious with the extension of the abandonment year. The soil bulk density decreased and porosity increased with the extension of the abandonment year. The difference of porosity and soil bulk density at the range of 0-40 cm of different abandoned land decreased after the land abandoned for 3 years. The quality of soil was decreased, while the soil permeability was improved. The soil physical properties changed obviously in 3 to 4 years after abandonment, so it is the key time for land management.

Research on anisotropy of shale oil reservoir based on rock physics model

Rock physics modeling is implemented for shales in the Luojia area of the Zhanhua topographic depression. In the rock physics model, the clay lamination parameter is introduced into the Backus averaging theory for the description of anisotropy related to the preferred alignment of clay particles, and the Chapman multi-scale fracture theory is used to calculate anisotropy relating to the fracture system. In accordance with geological features of shales in the study area, horizontal fractures are regarded as the dominant factor in the prediction of fracture density and anisotropy parameters for the inversion scheme. Results indicate that the horizontal fracture density obtained has good agreement with horizontal permeability measured from cores, and thus confirms the applicability of the proposed rock physics model and inversion method. Fracture density can thus be regarded as an indicator of reservoir permeability. In addition, the anisotropy parameter of the P-wave is higher than that of the S-wave due to the presence of horizontal fractures. Fracture density has an obvious positive correlation with P-wave anisotropy, and the clay content shows a positive correlation with S-wave anisotropy, which fully shows that fracture density has a negative correlation with clay and quartz contents and a positive relation with carbonate contents.

Anisotropy rock physics model for the Longmaxi shale gas reservoir,Sichuan Basin,China

The preferred orientation of clay minerals dominates the intrinsic anisotropy of shale. We introduce the clay lamination （CL） parameter to the Backus averaging method to describe the intrinsic shale anisotropy induced by the alignment of clay minerals. Then, we perform the inversion of CL and the Thomsen anisotropy parameters. The direct measurement of anisotropy is difficult because of the inability to measure the acoustic velocity in the vertical direction in boreholes and instrument limitations. By introducing the parameter CL, the inversion method provides reasonable estimates of the elastic anisotropy in the Longmaxi shale. The clay content is weakly correlated with the CL parameter. Moreover, the parameter CL is abnormally high at the bottom of the Longmaxi and Wufeng Formations, which are the target reservoirs. Finally, we construct rock physics templates to interpret well logging and reservoir properties.