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Therapeutic Communication Methods Targeting Families and Family Members: A Literature Review
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作者 Taketo Watsuji Naohiro Hohashi 《Open Journal of Nursing》 2024年第1期11-26,共16页
Background and Purpose: Therapeutic communication is a new term in family health care nursing, defined by Hohashi (2019) as a method of family intervention, and characterized by inclusion of not only verbal conversati... Background and Purpose: Therapeutic communication is a new term in family health care nursing, defined by Hohashi (2019) as a method of family intervention, and characterized by inclusion of not only verbal conversation but also nonverbal interaction. However, specific therapeutic communication methods have not been systematized. The purpose of this study was to clarify therapeutic communication methods for families/family members from the perspectives of verbal communication and non-verbal communication through a review of existing literature. Methods: We conducted a search using the medical literature databases PubMed and Ichushi-Web using the keywords “therapeutic communication”. Analysis was performed on seven articles from PubMed and 14 articles from Ichushi-Web that described therapeutic communication methods performed by healthcare professionals for families/family members. Through directed content analysis, therapeutic communication methods were subcategorized, and classified into three categories: verbal communication, non-verbal communication, and verbal/non-verbal communication. Results: A total of 23 subcategories were extracted. Verbal communication included 11 subcategories, such as “asking questions using the communicatee’s words as they are”. Non-verbal communication included five subcategories, such as “noticing changes in the content of the communicatee’s story”. And verbal/non-verbal communication featured seven subcategories, such as “making the communicatee aware of one’s own beliefs”. Conclusion: Therapeutic communication methods included basic care/caring in family interviews/meetings, as well as verbal communication and non-verbal communication that act on family/family members’ beliefs. It is believed that changes in family/family members’ beliefs can be used to eliminate, reduce, or improve problematic conditions in the family. . 展开更多
关键词 Therapeutic Communication family Nursing family Interview/Meeting family Belief Systems Theory Literature Review
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基于MUSIC算法特征值损伤因子的板状结构损伤程度评估
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作者 阎石 朱瑞峰 《无损检测》 CAS 2024年第8期63-69,共7页
研究了多重信号分类(MUSIC)算法在板状结构损伤检测中的应用,提出一种基于MUSIC算法特征值的损伤因子,为基于MUSIC算法的板状结构损伤成像技术提供了一种可靠的损伤程度评估理论。首先利用MUSIC算法计算的高精度特征值和Lamb波损伤散射... 研究了多重信号分类(MUSIC)算法在板状结构损伤检测中的应用,提出一种基于MUSIC算法特征值的损伤因子,为基于MUSIC算法的板状结构损伤成像技术提供了一种可靠的损伤程度评估理论。首先利用MUSIC算法计算的高精度特征值和Lamb波损伤散射信号幅值的相关性,采用Abaqus有限元仿真软件模拟不同程度的损伤,将板状结构中的损伤成像定位之后,根据散射信号将结构损伤程度转化为特征值变化量,根据特征值计算损伤因子,建立损伤评估模型预测损伤程度,并通过试验验证其正确性。试验结果表明,在合适的激励频率下,特征值损伤因子随着损伤程度的增加呈现出线性变化,能较好地反映损伤程度;该方法具有较高的准确性和稳定性,在一定损伤程度内能够有效地反映结构损伤程度。 展开更多
关键词 music算法 特征值 损伤因子 有限元 损伤程度
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MUSIC学习动机模型在仪器分析教学中的实践与研究
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作者 王丽聪 堵国君 《化纤与纺织技术》 CAS 2024年第6期184-186,共3页
基于MUSIC(Empowerment-Usefulness-Success-Interest-Caring)学习动机模型开展仪器分析教学工作,是目前调动学生学习积极性和锻炼自主学习能力的重要依托。文章立足MUSIC学习动机模型赋权分析、有用研究、成功探索、兴趣指引、关怀体... 基于MUSIC(Empowerment-Usefulness-Success-Interest-Caring)学习动机模型开展仪器分析教学工作,是目前调动学生学习积极性和锻炼自主学习能力的重要依托。文章立足MUSIC学习动机模型赋权分析、有用研究、成功探索、兴趣指引、关怀体验步骤,深入分析实践应用准则,并围绕现有教学不足确定优化方向,通过明晰学习任务目标、探寻知识需求、构建多样实践活动、立足教材整合资源、师生深度互动评价等策略,促进高职学生良性成长。 展开更多
关键词 music学习动机模型 仪器分析 赋权 师生互动
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Clinical and Familial Characteristics of Ten Chinese Patients with Fatal Family Insomnia 被引量:9
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作者 SHI Qi CHEN Cao +5 位作者 GAO Chen TIAN Chan ZHOU Wei ZHANG BaoYun HAN Jun DONG Xiao Ping 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第4期471-475,共5页
Objective Fatal familial insomnia (FFI) is an autosomal dominant prion disease characterized clinically by inattention, sleep loss, dysautonomia, and motor signs. This study is aimed to investigate clinical and fami... Objective Fatal familial insomnia (FFI) is an autosomal dominant prion disease characterized clinically by inattention, sleep loss, dysautonomia, and motor signs. This study is aimed to investigate clinical and familial characteristics often Chinese Patients with FFI. Methods We identified ten FFI cases from the surveillance network for Creutafeldt- Jakob disease (CJD) in China.Final diagnosis of FFI cases was made in accordance with the WHO criteria for CJD.The main clinical features and family histories of these ten FFI cases were analyzed. Results The median age of ten cases at onset was 38 years (from 19 to 55). The foremost symptoms seemed to be various, including sleep disturbances, vision disorder, dizziness and anorexia. Sleep disturbances appeared in all cases and lasted in the whole clinical courses. Progressive sympathetic symptoms, memory loss, movement disturbances, myoclonus and hypertension were also frequently observed. The median duration of the disease was 9.5 months. EEG and MRI did not figure out special abnormality. 14-3-3 protein in CSF was positive in five out of eight tested patients. Clear family histories were identified in 8 patients. Conclusion The data from our study confirm that the Chinese FFI cases have similar clinical characteristics as that of the Caucasian cases. Compared with other genetic CJD associated mutations, the genetic frequencies of D178N in PRNP are apparently high among the Chinese cases. 展开更多
关键词 Fatal family insomnia D178N PRNP Creutzfeldt-Jakob disease CJD
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Factors Affecting the Perception of Family Functioning among Couples in Child-Rearing Japanese Families 被引量:1
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作者 Junko Honda Yuuri Nakai +1 位作者 Shota Kakazu Naohiro Hohashi 《Open Journal of Nursing》 2015年第5期407-415,共9页
In family healthcare nursing, the family system unit (i.e., a group in which the members, seen as a whole, mutually interact) is the target of care. As nurses tend to obtain family-related information from particular ... In family healthcare nursing, the family system unit (i.e., a group in which the members, seen as a whole, mutually interact) is the target of care. As nurses tend to obtain family-related information from particular family members in the clinical setting, when assessing families, they often confront the issue of the differences between the theoretical level and methodological level. Although this issue needs resolving for evidence-based family nursing practice, sufficient research is lacking on the methodology related to family assessment. The present study aimed to clarify the factors that affected evaluation of family functioning among couples. Semi-structured interviews were conducted with 10 child-rearing families (couples) using the Survey of Family Environment (SFE) as a family functioning scale. Content analysis identified 12 factors that affected discrepancies in the couples’ evaluations and eight factors that affected agreement in those evaluations. These factors were classified into three categories: factors concerning family or family members;factors concerning questions related to the SFE;and factors concerning the view of the family as a whole. The results of this study should contribute to the development of family assessment tools and effective methods for evaluation of family care. 展开更多
关键词 family FUNCTIONING DISCREPANCY Survey of family ENVIRONMENT (SFE) Japan Concentric Sphere family ENVIRONMENT Theory (CSFET)
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Assessment of Quality of Life, Family Function and Family Empowerment for Families Who Provide Home Care for a Child with Severe Motor and Intellectual Disabilities in Japan 被引量:2
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作者 Rie Wakimizu Keiko Yamaguchi +6 位作者 Hiroshi Fujioka Chieko Numaguchi Kaori Nishigaki Naho Sato Miyuki Kishino Hiroshi Ozawa Nobuhiro Iwasaki 《Health》 CAS 2016年第4期304-317,共14页
Background: About 70% of Japanese children with severe motor and intellectual disabilities (SMID) live at home, and the number is increasing. Family members have an enormous burden of daily physical care for these chi... Background: About 70% of Japanese children with severe motor and intellectual disabilities (SMID) live at home, and the number is increasing. Family members have an enormous burden of daily physical care for these children. A top priority is to understand quality of life (QoL), family function, and family empowerment to effectively support these families. We aimed to assess current living situations of families with a SMID child, and to reveal the relationships between QoL, family function, and family empowerment. Methods: Sixty-five family members from 34 families with a SMID child participated in this study. We assessed 5 parameters using the Japanese versions of the following instruments: World Health Organization Quality of Life 26 (WHOQOL26), Kinder Lebensqualitats Fragebogen (KINDL), Family Assessment Device (FAD), Family Adaptability and Cohesion Evaluation Scale KG-4 (FACESKG-4), and Family Empowerment Scale (FES). Correlation and multiple regression analyses were conducted;QoL score was the objective variable. Results: Participants included 54 parents (34 mothers, 20 fathers) and 11 siblings. The mean age of SMID children was 10.4 ± 5.03 years. Twenty-two children needed multiple types of medical care. The mean age of parents and siblings was 41.5 ± 6.16 years and 15.5 ± 2.35 years, respectively. The mean QoL score (3.28 ± 0.5) was similar to the Japanese average. The mean KINDL score (77.2 ± 12.1) was higher than those of previous studies. The mean FAD score was 1.97 ± 0.32. For FACEKG-4, the score of adaptability was correlated with WHOQOL score (r = 0.459, p < 0.05). The mean score of FES was 113.6 ± 14. As the result of multiple regression analysis, lower family FAD scores ([sb] = ?0.61, p < 0.01) indicated higher family function and greater age of participants (sb = 0.495, p < 0.01) was correlated with higher WHOQOL scores (F = 15.208, p < 0.01). Conclusions: Our results indicated that the individual QoL depended on the age of participants (equals the years of experience caring for a SMID child) and the recognition of family function as a whole. Thus, to improve family members’ QoL, we should focus on individuals and also approach the family as a whole. 展开更多
关键词 Home Care CAREGIVERS family JAPAN Quality of Life Children with Disabilities Severe Motor and Intellectual Disabilities
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Family empowerment and quality of life of parents raising children with Developmental Disabilities in 78 Japanese families 被引量:5
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作者 Rie Wakimizu Keiko Yamaguchi Hiroshi Fujioka 《International Journal of Nursing Sciences》 2017年第1期38-45,共8页
Objectives: The families of these children experience distress both at the time of diagnosis and afterward.A top priority is to understand family empowerment,family function,and family members' quality of life (Qo... Objectives: The families of these children experience distress both at the time of diagnosis and afterward.A top priority is to understand family empowerment,family function,and family members' quality of life (QoL) and to effectively support these families in Japan.The objective of this study was to assess the actual conditions of families living with children having DDs and to explore the factors associated with family empowerment and parents' QoL.Methods: We surveyed ninety-three parents (78 mothers,15 fathers) from 78 families which lived with children with DDs in the capital region of Japan.We assessed two main outcomes using the Japanese versions of the following instruments: Family Empowerment Scale (FES),World Health Organization Quality of Life 26 (WHOQOL26),and other six outcomes.Correlation and multiple regression analyses were conducted.Results: No medication,cooperation with child rearing,assistance from a developmental support center,solved problems related to child rearing,and higher scores in Problem Solving contributed to higher FES scores.Higher WHOQOL26 scores were related to being a full-time housewife,higher self-esteem,no developmental support,a broad emotional support network,higher scores in Problem Solving and Role Function,and lower scores in Affective Reaction and General Function.Conclusions: We revealed that family empowerment and QoL of parents rearing children with DDs in Japan were affected by various subscales of family function and other family attributes.Effective interventions for improving family empowerment and QoL should be researched in the future. 展开更多
关键词 Developmental disabilities family empowerment Japan Multiple regression analysis Quality of life Social support
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FAMILIAL AMYLOID POLYNEUROPATHY──CLINICAL REPORT OF A FAMILY 被引量:2
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作者 李延峰 郭玉璞 +1 位作者 池田修一 方定华 《Chinese Medical Sciences Journal》 CAS CSCD 1996年第2期113-116,共4页
This paper reports a familial amyloid polyneuropathy (FAP) family in China. This family being investigated had 69 members of five generations. From the third generation, there have been 16 patients. The age of onset w... This paper reports a familial amyloid polyneuropathy (FAP) family in China. This family being investigated had 69 members of five generations. From the third generation, there have been 16 patients. The age of onset was about 3 to 5 decades. The initial symptoms were autonomic nerve symptoms, such as impotence, dyspepsia and diarrhoea, associated with the sensory loss of lower extremities. As the disease progressed, the upper extremities and motor ability were also involved. The duration of disease course was about 8-10 years, most patients died of infection and cachexia. Sural biopsy in 3 patients had showed positive Congo red staining. From the clinical view, this FAP family is similar to FAP I found in Japan. The true classification, however, should be confirmed by further genetic analysis. 展开更多
关键词 familial amyloid polyneuropathy sural biopsy
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Family empowerment and associated factors in Japanese families raising a child with severe motor and intellectual disabilities 被引量:3
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作者 Rie Wakimizu Hiroshi Fujioka +1 位作者 Kaori Nishigaki Akemi Matsuzawa 《International Journal of Nursing Sciences》 2018年第4期370-376,共7页
Objectives:Family caregivers raising children with severe motor and intellectual disabilities(SMID)experience the enormous burden of care.The concept of family empowerment is one of the important assessment indexes of... Objectives:Family caregivers raising children with severe motor and intellectual disabilities(SMID)experience the enormous burden of care.The concept of family empowerment is one of the important assessment indexes of family nursing from the perspective of providing comprehensive support for these families.The objective of this study was to identify the factors associated with the empowerment of families raising a child with SMID in Japan.Methods:We conducted a nationwide questionnaire survey involving 1659 primary caregivers raising a child with SMID through 89 special schools.We assessed the main outcomes using the Family Empowerment Scale(FES).We then conducted a multiple linear regression analysis to reveal the factors associated with family empowerment.Results:In total,1362 primary caregivers were included in our study.Our results show that factors contributing to high FES scores are higher age of the primary caregiver,higher education,greater recognition of regional support,lower childcare burden,higher utilization of home visit services,higher usage of a childcare institution,higher household income,and stronger family bonding.Conclusion:Healthcare professionals should carefully assess the state of family empowerment of the primary caregivers who are younger and those who have low education,low household income,high childcare burden,and fragile bonding with the family.Second,they should encourage such families to use regional support resources for childcare.That is,policy makers should consider ways to promote home visits and institutional services for the care of children with SMID,aiming especially for the provision of well-coordinated care and services. 展开更多
关键词 CAREGIVERS Child care Disabled children family empowerment Home nursing Intellectual disability Japan Social supports
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Identification of a LMNA (c.646C>T) variant by whole-exome sequencing in combination with a dilated cardiomyopathy (DCM) related gene filter in a family with familiar DCM 被引量:2
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作者 Liang Chen Zhongyin Zhou +4 位作者 Huihe Lu Ye Xie Gang Li Jianfei Huang Dongsheng Zhao 《The Journal of Biomedical Research》 CAS CSCD 2018年第4期314-316,共3页
Dilated cardiomyopathy(DCM)is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM... Dilated cardiomyopathy(DCM)is characterized by the dilated heart chambers and reduced systolic function in the absence of specific aetiology[1].Approximately one third of DCM cases are hereditary.In recent years,DCM concomitant with arrhythmias and sudden death resulting from gene mutation has been widely 展开更多
关键词 related gene filter in a family with familiar DCM AVB Identification of a LMNA c.646C T variant by whole-exome sequencing in combination with a dilated cardiomyopathy
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How to Apply Family Education in Little Women to Chinese Families
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作者 李娜 《海外英语》 2014年第2X期121-122,共2页
In recent years in China,family education has become more and more important.Family plays the most crucial role in children's education.So more and more parents begin to pay much more attention to family education... In recent years in China,family education has become more and more important.Family plays the most crucial role in children's education.So more and more parents begin to pay much more attention to family education than before.However,what ways are best for them to use?Most parents have no idea at all and some are trying to use some education methods learned from books.Little Women is a book from which we can learn a lot of useful things,the obvious one is family education.This novel was written by an American author in 19th century.As a result,both time and place are a little far away from people in China.But at that time,the March's family education did work very well and made far-reaching influence.So in the first part in this paper what will be introduced in is about finding out how the March's family dealt with those unpleasant things,and the second part will discuss some disadvantages of Chinese family education,then the third part will see if March's ways could be used in Chinese families or how to make some changes about their ways so that those ways could work in Chinese families as well as they did in the March's. 展开更多
关键词 LITTLE WOMEN family EDUCATION advantages disadvant
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Enhancing the awakening to family engagement bundle with music therapy 被引量:1
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作者 Ariel M Modrykamien 《World Journal of Critical Care Medicine》 2023年第2期41-52,共12页
Survivors of prolonged intensive care unit(ICU)admissions may present undesirable long-term outcomes.In particular,physical impairment and cognitive dysfunction have both been described in patients surviving episodes ... Survivors of prolonged intensive care unit(ICU)admissions may present undesirable long-term outcomes.In particular,physical impairment and cognitive dysfunction have both been described in patients surviving episodes requiring mechanical ventilation and sedation.One of the strategies to prevent the aforementioned outcomes involves the implementation of a bundle composed by:(1)Spontaneous awakening trial;(2)Spontaneous breathing trial;(3)Choosing proper sedation strategies;(4)Delirium detection and management;(5)Early ICU mobility;and(6)Family engagement(ABCDEF bundle).The components of this bundle contribute in shortening length of stay on mechanical ventilation and reducing incidence of delirium.Since the first description of the ABCDEF bundle,other relevant therapeutic factors have been proposed,such as introducing music therapy.This mini-review describes the current evidence supporting the use of the ABCDEF bundle,as well as current knowledge on the implementation of music therapy. 展开更多
关键词 BUNDLE DELIRIUM Mechanical ventilation MOBILITY music therapy
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基于卡尔曼滤波与MUSIC算法的传感阵列定向方法
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作者 刘东甲 陶雄俊 +2 位作者 王安军 郑全福 罗林根 《水电能源科学》 北大核心 2024年第9期217-220,共4页
对局放源信号的准确测量与有效识别是局部放电检测、定位及分析的关键。受电磁传感器方向特性灵敏度局限,现有基于到达角(AOA)定位的局部放电定位方法主要运用于声音信号。为此,提出一种卡尔曼滤波算法与多信号分类器(MUSIC)算法相结合... 对局放源信号的准确测量与有效识别是局部放电检测、定位及分析的关键。受电磁传感器方向特性灵敏度局限,现有基于到达角(AOA)定位的局部放电定位方法主要运用于声音信号。为此,提出一种卡尔曼滤波算法与多信号分类器(MUSIC)算法相结合的特高频传感阵列定向方法,即首先采用卡尔曼滤波算法能够有效处理电磁幅值信号,减小信号波动性及测量误差,大大提升信号测量精度;然后针对单一传感器建立了传感器方向性的参考矩阵,对任意来波信号使用MUSIC算法进行数据匹配,从而得到精确的来波方向;最后经过试验验证,所提算法可将传感器阵列的方向识别结果误差减小至5°以内,提升了测量精度。 展开更多
关键词 局部放电 方向性 卡尔曼滤波 music
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基于DSP的快速MUSIC测角算法 被引量:1
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作者 金芳晓 崔伟 《现代雷达》 CSCD 北大核心 2024年第1期26-30,共5页
基于阵列信号处理的MUSIC算法,由于其超高的角分辨率和角精度,受到广泛的关注。但是其高运算复杂度,较大地限制了算法的硬件实现。为此,基于MUSIC算法的基本原理,文中分析了该算法在DSP(TI1843)硬件系统实现中关键子步骤的运行时长。针... 基于阵列信号处理的MUSIC算法,由于其超高的角分辨率和角精度,受到广泛的关注。但是其高运算复杂度,较大地限制了算法的硬件实现。为此,基于MUSIC算法的基本原理,文中分析了该算法在DSP(TI1843)硬件系统实现中关键子步骤的运行时长。针对最为耗时和占用内存最大的空间谱构建和谱峰搜索子步骤,分别提出了便于工程实现的简化方法,并通过硬件平台移植验证了算法的可行性,对比发现该方法大大减少了运算时间和内存空间,具有较高实际应用价值。 展开更多
关键词 music算法 运算复杂度 空间谱 谱峰搜索 DSP系统
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Work-Family Conflict in Nursing: The Role of Work Schedules, Familial Antecedents and Emotional Regulation
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作者 Claudia Gonnelli Mirian Agus Rosalba Raffagnino 《Open Journal of Medical Psychology》 2018年第4期123-147,共25页
This paper explores the influences of Emotional Regulation (ER) and work schedules on work-family conflict (WFC) among Italian nurses, also accounting for some familial variables. The data used in this study come from... This paper explores the influences of Emotional Regulation (ER) and work schedules on work-family conflict (WFC) among Italian nurses, also accounting for some familial variables. The data used in this study come from a survey conducted on 191 nurses working in two public hospitals of Tuscany (Italy). Stepwise multiple regressions were applied to examine the relationships among these variables, using the WFC as dependent variable. We found that some work related dimensions had direct effects on WFC outcomes;however, these impacts on the criterion variables are modified by the effects exerted by specific ER strategies. 展开更多
关键词 WORK family CONFLICT EMOTION Regulation WORK SCHEDULE FAMILIAL Status FAMILIAL Support
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Transmission of family health information within families
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作者 Patricia Newcomb Barbara Raudonis +1 位作者 Diane Snow Denise Cauble 《Open Journal of Nursing》 2012年第1期15-22,共8页
Background and Aims: A comprehensive family health history still offers the best data for calculating risk of most complex diseases, but lack of informant accuracy hinders its use. Young adults transitioning from the ... Background and Aims: A comprehensive family health history still offers the best data for calculating risk of most complex diseases, but lack of informant accuracy hinders its use. Young adults transitioning from the parental home to more independent university life may be poor historians. The purpose of this study was to describe the quality of family health information acquired by young university students and to characterize the process by which they learn family health facts. Methods: Thematic content analysis was applied to interviews with undergraduate students enrolled in diverse classes across disciplines at a public US university. Results: Two processes, hanging around and trickling down, described the ways young adults learned family health information. The majority of respondents described both empowerment and a sense of vulnerability that resulted from having their family health information. Conclusions: Family health history provided by young adult students is characterized by inaccuracies related to lack of information and misunderstanding of information that is available. Young students are typically transitioning from the care of local primary care physicians into relationships with new healthcare providers, and are interested in family health history. Thus, this transition is an opportunity for nurses to construct an organized family health history with them. 展开更多
关键词 family HEALTH HISTORY YOUNG ADULT family Communication Qualitative Research
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Perceived Program Components of <i>Omotenashi Family Experiences Learning Program</i>in Japan: Qualitative Study of Families of Persons with Mental Disorders
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作者 Masako Kageyama Keiko Yokoyama +1 位作者 Yukako Nakamura Iwao Oshima 《Open Journal of Nursing》 2017年第6期671-682,共12页
Families need sufficient learning opportunities about mental illness. Therefore, family peer education program has been developed in Japan following the U.S. and Hong Kong. We aimed to identify program components that... Families need sufficient learning opportunities about mental illness. Therefore, family peer education program has been developed in Japan following the U.S. and Hong Kong. We aimed to identify program components that families recognize which would provide suggestions in modifying the program. We used qualitative and inductive study design. Data were collected through group interviews for six family research participants. We coded the data to focus on relationships between program components, program processes, and impacts. Data Analysis resulted in seven assumptions based on causal relationships and three types of program components: program form, learning style and facilitation skills. The program form is family-led peer group, closed-membership, 5 times per course, and small group. The learning style is combination of textbook and experiential knowledge, family peer learning, and sharing experiences. The facilitation skills are group work focusing on strengths of family members, the acceptance of emotional disclosure, omotenashi, and teamwork skills. 展开更多
关键词 Mental Disorders SCHIZOPHRENIA family Support family Education PROGRAM Evaluation PROGRAM Component
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改进MUSIC算法的超声波测风方法研究
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作者 唐心亮 宋欣朔 倪永婧 《重庆理工大学学报(自然科学)》 CAS 北大核心 2024年第4期283-289,共7页
针对传统超声波测风装置测风精度不高、抗噪声能力弱,提出了一种改进多重信号分类(multiple signal classification,MUSIC)算法的超声波测风方法。采用一种弧形6阵元超声波传感器阵列的测风结构,推导其阵列流型;在此基础上,添加小波阈... 针对传统超声波测风装置测风精度不高、抗噪声能力弱,提出了一种改进多重信号分类(multiple signal classification,MUSIC)算法的超声波测风方法。采用一种弧形6阵元超声波传感器阵列的测风结构,推导其阵列流型;在此基础上,添加小波阈值降噪算法提高信号信噪比,降低噪声信号协方差矩阵的秩;再使用PHAT加权广义互相关时延估计算法以提高时延估计的准确性,同时根据时延关系对传统MUSIC算法矢量矩阵进行改进;最后通过MUSIC算法实现对风速风向的测量。理论分析与仿真结果表明:改进后的MUSIC算法具有较好的抗噪性能和较高的风参数测量精度,测量风速绝对误差达到0.15 m/s,风向绝对误差达到2°,可以应用于对风参数要求较高的场景。 展开更多
关键词 阵列信号处理 music算法 小波阈值降噪 广义互相关 风速风向测量
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Family-based association analysis of alcohol dependence implicates KIAA0040 on Chromosome 1q in multiplex alcohol dependence families
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作者 Shirley Y. Hill Bobby L. Jones +1 位作者 Nicholas Zezza Scott Stiffler 《Open Journal of Genetics》 2013年第4期243-252,共10页
Background: A previous genome-wide linkage study of alcohol dependence in multiplex families found a suggestive linkage result for a region on Chromosome 1 near microsatellite markers D1S196 and D1S2878. The KIAA0040 ... Background: A previous genome-wide linkage study of alcohol dependence in multiplex families found a suggestive linkage result for a region on Chromosome 1 near microsatellite markers D1S196 and D1S2878. The KIAA0040 gene has been mapped to this region (1q24-q25). A recent genome-wide association study using SAGE (the Study of Addiction: Genetics and Environment) and COGA (Collaborative Study on the Genetics of Alcoholism) found five SNPs within the KIAA0040 gene significantly associated with alcohol dependence. A meta-analysis using data from these sources also found the KIAA0040 gene significantly associated with alcohol dependence. Methods: Using family data consisting of 1000 individuals with phenotypic data (762 with both phenotype and DNA), finer mapping of a 0.3 cM region that included the KIAA0040 gene and a flanking gene was undertaken using SNPs with minor allele frequency (MAF) ≥ 0.15 and pair-wise linkage disequilibrium (LD) of r2 < 0.8 using the HapMap CEU population. Results: Significant FBAT p-values were observed for six SNPs, four within the KIAA0040 gene (rs2269650, rs2861158, rs1008459, rs2272785) and two adjacent to KIAA0040 (rs10912899 and rs3753555). Five haplotype blocks of varying size were identified using HAPLOVIEW. Analysis using the haplotype-based test function of FBAT revealed one two-SNP block (rs1008459rs2272785) associated with alcohol dependence. This block showed a pattern of transmission in which one haplotype, CT, with a frequency of 0.577 was found to be over-transmitted to affected offspring (p = 0.017) while another haplotype, AG, with a frequency of 0.238 was found to be under-transmitted to affected offspring (p = 0.006). A three-SNP block (rs1008459rs2272785-rs375355) showed an overall significant association (p = 0.011) with alcohol dependence with the haplotype ACT over-transmitted to affected offspring (p = 0.016) and the haplotype GAG undertransmitted (p = 0.002). Conclusions: Family-based association analysis shows the KIAA0040 gene significantly associated with alcohol dependence. The potential importance of the KIAA0040 gene for AD risk is currently unknown. However, the present results support earlier findings from a genome-wide association study. 展开更多
关键词 KIAA0040 ALCOHOL DEPENDENCE Multiplex Families
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Familial aggregation and heritability for cardiovascular risk factors: a family based study in Punjab, India
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作者 Raman Kumar Bdarud Doza 《Natural Science》 2010年第7期732-736,共5页
Background: It is well established that the people with elevated SBP, DBP, BMI and WHR are more prone to cardiovascular disease. However, very few studies have focused on the amount of familial aggregation and heritab... Background: It is well established that the people with elevated SBP, DBP, BMI and WHR are more prone to cardiovascular disease. However, very few studies have focused on the amount of familial aggregation and heritability of these cardiovascular risk factors in Indian population. Therefore, purpose of this study was to investigate the familial aggregation of blood pressures with respect to certain anthropometric traits and to determine the relative roles of heredity in the etiology of SBP and DBP in a sample of families with three generations. Methods: The study has been conducted through house to house family study among three generations such as offspring, parent and grandparent in a scheduled caste community (Ramdasia) in Punjab. A total of 1400 individuals, constituting 380 families were surveyed for blood pressure, pulse rate, pulse pressure and anthropometric measurements to study familial aggregation and heritability for cardiovascular risk factors. The analysis represents a multivariate model which includes the each individual family data for estimation of familial correlation and heritability. Results: All risk factors showed positive familial correlation but magnitudes are different in va rious pairs of combination. Correlations generally are higher among genetically close relatives such as brothersisters or parentoffspring and are lower among spouses. The estimated heri tabilities were 22% for systolic and 27% for diastolic blood pressure, 19% for BMI and 17% for WHR. Conclusions: These results indicate a strong familial aggregation of cardiovascular risk factors such as SBP and DBP in this population and also showed that this familial influence can be detected from anthropometric mea surements and genetic closeness. Almost all anthropometric variables were found to be significant with blood pressures among three ge nerations. 展开更多
关键词 FAMILIAL AGGREGATION HERITABILITY Risk Factors Ramdasia POPULATION PUNJAB
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