Observation on Therapeutic Effect of Lotus Needle Cupping Therapy for Removing Blood Stasis in Zhuang Medicine on PHN and Its Influ-ence on Inflammatory Mediators

[Objectives]To observe the clinical effect of the lotus needle cupping therapy for removing blood stasis in Zhuang medicine in treating PHNand its influence on inflammatory factors.[Methods]96 patients with PHN were randomly divided into three groups:lotus nee-dle cupping therapy group,TCM surrounding acupuncture group and gabapentin group.Venous blood and acupoint blood were collected at 0,21 and 42 d of treatment,and the expression levels of 5-HT,SP and CGRPinflammatory mediators were detected before and after treatment.The changes of VAS scores before,during and after treatment and the clinical efficacy were observed.[Results]The total effective rate of the lotus needle cupping group was 87.50%,which was better than that of the TCM acupuncture group(81.25%)and the gabapentin group(62.50%);after treatment,the VAS scores and the expression of inflammatory mediators in the three groups of patients were lower than those before treatment,and the decrease was more significant in the treatment group(P<0.05).[Conclusions]The lotus needle cupping therapy for removing blood stasis in Zhuang medicine is effective in treating PHN,and its mechanism is to reduce the release of inflammatory media-tors,reduce hyperalgesia,relieve pain and improve the quality of life of patients.

CHINESE HUAI TANG NINE ACUPUNCTURE NEEDLES: RESEARCH ON THE NEW NINE ACUPUNCTURE NEEDLES THERAPY AND THE NEEDLING INSTRUMENTS (CONTINUED)

PART TWOThe Research on Chinese Huai TangNine Acupuncture Needles TherapyI The theoretical basis of ChineseHuai Tang Nine Needles Therapy.1) The kernel of the theoretical basis ofChinese Huai Tang Nine Needles Therapy.Chinese Huai Tang Nine Needles Therapyis to give full play to the treatment action of thespecifity and entirety of each needle. The speci-fity means that each needle has its own

Study of Mongolian Warming Needle Acupuncture Therapy

The Mongolian warming needle acupuncture therapy is a Mongolian traditional external treatment method that uses special silver needles to insert specific acupoints on the human body,and then stimulates them with warm acupuncture to achieve the purpose of disease prevention and treatment.This paper reviewed the theoretical basis,acupuncture methods,acupuncture classification,acupuncture tools,acupuncture points,indications,and contraindications of Mongolian acupuncture.Besides,it also summarized the clinical application of the Mongolian warming needle acupuncture therapy.In addition,it elaborated the its principle of regulating cold and heat in the body,leading the disease out,dialectically coordinating the whole,and changing the local part,highlighting its important position in medicine,so as to better promote clinical practice.

Effect of Wei’s triple nine needling therapy on flash visual evoked potentials in rats with traumatic optic neuropathy

Objective:To investigate the effect of Wei’s triple nine needling therapy on the N2-P2 wave of the flash visual evoked potential(FVEP)in rats of the of the transverse directional pulling model.Methods:Thirty-six Wistar rats were randomly grouped,nine were in normal control group without any treatment,and the remaining 27 were surgically modelled in the right eyes.Eighteen of these rats were randomly divided into a Wei’s triple nine needling therapy group and a model group of nine rats each after the TON model was made using the transverse quantitative retraction method.The other 9 rats were sham-operated,and only the optic nerve was exposed without retraction.On the next day of modelling,the Wei’s triple nine needling therapy group was treated with Wei’s triple nine needling therapy for 20 minutes/1 time/1 day for 14 days.The model group,sham-operated group and normal control group were not intervened.Wei's triple nine acupoints were represented as follows:1st link:"Jingming"(BL1)and"Chengqi"(ST1);2nd link:"Sizhukong"(SJ23)penetrating"Taiyang"(EX-HN5);and the third:"Fengchi"(GB 20)and"Taichong"(LV3).The FVEP of each group was observed on 1d,7d and 14d.The FVEP of each group was observed on 1d,7d and 14d.Results:Compared with the model group,the N2 wave latency and P2 wave latency were shortened in the Wei’s triple nine needling therapy on 1d(P<0.05,P<0.01);on 7d,their N2 wave latency was shortened(P<0.01)and the N2-P2 wave amplitude was increased compared with the model group(P<0.05);on 14d,their P2 wave latency was shortened(P<0.05)and the N2-P2 wave amplitude was increased.There was no statistical difference in N2 wave latency,P2 wave latency and N2-P2 wave amplitude in the sham-operated group on 1d,7d and 14d(P>0.05).The delayed N2 and P2 wave latencies in the model group did not improve from 1d to 14d(P>0.05)and the amplitude decreased throughout,showing a significant difference on 14d compared to 1d(P<0.05).In contrast,the N2 wave latency in Wei’s triple nine needling therapy group was not significantly different until 7d to 14d(P<0.05);its P2 wave latency,although significantly delayed from 1d to 7d(P<0.05),recovered on 14d and reached a level that was not statistically different from 1d and 7d(P>0.05).There was also no significant decrease in N2-P2 wave amplitude between 1d and 14d in Wei’s triple nine needling therapy group(P>0.05).Conclusion:In this experiment,the TON rat model was successfully established by the transverse quantitative retraction method,and the treatment of TON rats with Wei’s triple nine needling therapy reduced the P2 wave delay of the FVEP electrophysiological signal and increased the N2-P2 amplitude,which had a certain positive effect on the repair of optic nerve injury,probably related to its effect of improving the conduction function of the optic nerve and protecting the retinal ganglion cells that had not been degenerated and necrosed.

Fire needle combined with blood-letting therapy for a case of 20-year trigeminal neuralgia

Background： Trigeminal neuralgia （TN） is a neuropathic pain syndrome. It is the most frequent cranial neuralgia and defined as sudden, usually unilateral and lightning-like, knife-like or burning-like recurrent episodes of pain within the distribution area of one or more divisions of the trigeminal nerve. Here we reported that an 81-year-old woman with TN who complained of severe pain on her right face showed a complete clinical relief after comprehensive therapy containing fire needle, filiform needle and blood-letting therapy. Methods： The patient was applied fire needle combined with filiform needle therapy （3 times / week for 4 months） and three consecutive fire needle combined with blood-letting therapy （3 times / week for one week）. Fire needle was inserted into the back points of Du meridian, the first lateral line of bladder meridian, the right spreading area of the trigeminal nerve and the points around the pain radiation site. The filiform needle acupuncture was applied to the points on the right face including Yuyao （EX-HN4）, Yangbai （GB14）, Toulinqi （GB15）, et al; points on the abdomen including Xiawan （RN10）, Qihai （RN16）, Guanyuan （RN14） and the bilateral points including Tianshu （ST25）, Daheng （SP15）, Zusanli （ST36）, et al. Finally, the three-edged fire needle punctured the points of Yangbai （GB41）, Shangguan （GB3）, Jiache （ST6） on the right face accompanied by the cupping method on the bleeding points. Results： The patient reported the complete disappearance of pain and could open mouth and eat normally. The face was normal and no triggering pain recurred after one-month follow-up. Conclusions： The fire needle combined with blood-letting therapy can cure the TN and might provide an alternative non-drug therapy for those patients who still suffered from TN after other medical treatments or whom that refused surgical treatment.

TREATMENT OF 247 CASES OF PROLAPSE OF LUMBAR INTERVERTEBRAL DISC WITH COMPREHENSIVE PLUM-BLOSSOM MAGNETIC NEEDLE THERAPY

Objective: To observe the therapeutic effect of comprehensive plum-blossom magnetic needle therapy on prolapse of lumbar intervertebral disc. Methods: 247 cases of prolapse of lumbar intervertebral disc were treated first with manual treatment and then with plum-blossom magnetic needle therapy and effect-increasing pad therapy at specified points and reactive points. Results: After treatment for 2 therapeutic courses,153 cases were cured accounting for 61.94%, 71 cases were markedly effective accounting for 28.75%, 22 cases were improved accounting for 8.91% and the rest one failed,accounting for 0.45%. Conclusion: The comprehensive plum-blossom magnetic needle therapy has a better therapeutic effect on prolapse of lumbar intervertebral disc.

TREATMENT OF VERTEBRAL－ARTERY TYPE CERVICAL SPONDYLOPATHY WITH NEEDLE－KNIFE THERAPY

In the present paper, 62 cases of vertebral artery type cervical spondylopathy were treated with needle knife therapy (acupotomy). After 2-6 sessions of treatment, 23 cases (37.1%) were cured, 19 (30.7%) showed marked improvement, 15 (24.2%) had some improvement and 5 (8.1%) failed in the treatment. The total effective rate was 91.9%. It indicates that acupotomy therapy is a highly effective remedy for treating vertebral artery type cervical spndylopathy.

“Four Sacral Needles” Therapy for Female Stress Incontinence

Objective： To make a retrospective control study of the curative effects of ＂Four sacral needles＂ method and conventional acupuncture therapy on female stress incontinence. Methods：A treatment group was treated by ＂Four sacral needles＂ method, in which four sacral points were electroacupunctured with special insertion of needles to excite the pudendal nerve and induce the rhythmic contraction of the pelvic floor muscles, thereby increasing the strength of the pelvic floor muscles and improving ability in urinary continence. A control group was treated by conventional acupuncture therapy, in which corresponding points were acupunctured according to syndrome-based classification. Results： In the 31 cases of the treatment group treated by ＂Four sacral needles＂ method, 100% symptom improvement occurred in 22（71.0% ）after an average of 21 treatments （3-63 treatments）. In the 34 cases of the control group treated by conventional acupuncture therapy, 100% symptom improvement occurred in 0 after 30 treatments. The curative effect was better in the treatment group than in the control group（p〈 0.01）.The curative effect improved with an increase in the number of treatments in the treatment group. Conclusion： ＂Four sacral needles＂ method is more effective than conventional acupuncture therapy in treating female stress incontinence.

梅花针配合首乌羌活汤治疗肝肾不足型斑秃临床观察

目的观察梅花针配合首乌羌活汤治疗肝肾不足型斑秃(AA)的临床效果。方法选取2020年1月—2020年6月大连市皮肤病医院门诊就诊的62例肝肾不足型AA患者作为研究对象,采用数字随机表法随机分为治疗组与对照组,各31例。对照组予口服首乌羌活汤治疗,治疗组在此基础上联用梅花针疗法,均以5周为1疗程,连续2个疗程。比较两组患者1个疗程和2个疗程后的效果。结果1个疗程后,治疗组总有效率为58.06%(18/31),高于对照组的25.81%(8/31)(P<0.05);2个疗程后,治疗组总有效率为83.87%(26/31),亦高于对照组的48.39%(15/31)(P<0.05)。结论梅花针配合首乌羌活汤治疗肝肾不足型AA,总有效率高、不良反应少,具有较好的临床效果。

AN OBSERVATION OF THE THERAPEUTIC EFFECT OF WARMING NEEDLING TECHNIQUE ON JIAJI POINTS FOR THE TREATMENT OF DEPRESSION AND ITS INFLUENCE ON EEG-α WAVE IN PATIENTS

Objective To discuss the therapeutic effect and mechanism of warming needling technique for the treatment of depression. Methods A total of 60 patients with depression were randomly divided into treatment group and control group with 30 cases each. The treatment group was treated with warming needle technique on the Jiaji points of the heart, lung, liver, spleen and kidney, control group with Amitriptyline, HAMD scale and the qualitative change of EEG-α wave were observed before and after the treatment. Results The total effective rate of treatment group was 100%, much better than that of the control group with 80% (P<0.05); the HAMD scale of treatment group was better than that of control group (P<0.05); the comparison of the improvement of somatic symptoms between treatment group and control group was significant (P<0.05); the comparison of frequency and amplitude of EEG-α wave was significant (P<0.05), there was no toxic and side effect in the treatment group. Conclusion Warming needling technique for depression has better effect than Amitriptyline, and there was no toxic and side effect in the treatment group. Warming needle technique can effectively regulate the frequency and amplitude EEG-α wave, and acts to improve depressive condition.

银质针联合循经走罐法在神经根型颈椎病患者中医护理中的应用

目的探讨银质针联合循经走罐法在神经根型颈椎病(CSR)患者中医护理中的应用效果。方法选取2022年3月至2024年2月三门峡武强中医院收治的108例CSR患者,采用随机数字表按1∶1∶1比例分为对照1组、对照2组、联合组,各36例。均实施常规基础护理,在此基础上对照1组给予银质针中医护理,对照2组给予循经走罐法中医护理,联合组给予银质针联合循经走罐法中医护理,护理观察4周。比较三组疼痛视觉模拟法(VAS)评分、颈椎活动度、病情变化程度[颈椎病临床评价量表(CASCS)、颈椎功能障碍指数(NDI)]、不良反应。结果干预2周、4周后,联合组VAS评分低于对照1组、对照2组(P<0.05);干预4周后,联合组颈椎前屈、后伸、左旋、右旋活动度高于对照1组、对照2组(P<0.05);干预4周后,联合组CASCS评分高于对照1组、对照2组,NDI评分低于对照1组、对照2组(P<0.05);联合组不良反应发生率13.89%与对照1组8.33%、对照2组11.11%比较,差异无统计学意义(P>0.05)。结论银质针联合循经走罐法干预能显著改善CSR患者的疼痛程度和颈椎活动度,促进病情恢复,安全性较高。

Endoscopic incisional therapy for benign esophageal strictures: Technique and results

Benign esophageal strictures refractory to the conventional balloon or bougie dilatation may be subjected to various adjunctive modes of therapy, one of them being endoscopic incisional therapy(EIT). A proper delineation of the stricture anatomy is a prerequisite. A host of electrocautery and mechanical devices may be used, the most common being the use of needle knife, either standard or insulated tip. The technique entails radial incision and cutting off of the stenotic rim. Adjunctive therapies, to prevent re-stenosis, such as balloon dilatation, oral or intralesional steroids or argon plasma coagulation can be used. The common strictures where EIT has been successfully used are Schatzki's rings(SR) and anastomotic strictures(AS). Short segment strictures(< 1 cm) have been found to have the best outcome. When compared with routine balloon dilatation, EIT has equivalent results in treatment na?ve cases but better long term outcome in refractory cases. Anecdotal reports of its use in other types of strictures have been noted. Post procedure complications of EIT are mild and comparable to dilatation therapy. As of the current evidence, incisional therapy can be used for management of refractory AS and SR with relatively short stenosis(< 1 cm) with good safety profile and acceptable long term patency.

Endoscopic ultrasound guided vascular access and therapy:A promising indication

Endoscopic ultrasound(EUS)is an imaging technique that has consolidated its role as an important tool for diagnosis and therapeutics.In recent years we have seen a dramatic increase in the number of EUS-guided therapeutic indications(celiac plexus neurolysis/block, pseudocyst drainage,etc).Preliminary reports have suggested EUS may also be used to guide vascular access for both imaging and treating different vascular diseases.This review aims to objectively describe the existing evidence in the field.

Effectiveness of fire needle combining with moist healing dressing to promote the growth of granulation tissue in chronic wounds:A case report

In this case study,we analyzed the wound-healing process of a patient with a chronic wound who underwent fire needle treatment,and we tracked the coverage of granulation tissue and decrease of slough and exudate.An 85-year-old man had repeated right shoulder and back pain,itching,and skin festering for more than 1.5 years.A fire needle was administered combined with moist dressing once every 5 days to promote wound healing.After six rounds of fire needle treatment,granulation tissue formed over the surface of the wound base,the depth of the wound had become shallow,and the wound area was reduced.No complications occurred during the intervention.Fire needle therapy combined with a moist wound-healing dressing can be an effective alternative approach in managing chronic wounds.

Accuracy of endoscopic ultrasound-guided needle aspiration specimens for molecular diagnosis of non-small-cell lung carcinoma

BACKGROUND Endoscopic ultrasonography-guided fine-needle aspiration(EUS-FNA)and endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)are highly sensitive for diagnosing and staging lung cancer.In recent years,targeted therapy has shown great significance in the treatment of non-small cell lung carcinoma(NSCLC).Using these minimally invasive techniques to obtain specimens for molecular testing will provide patients with a more convenient diagnostic approach.AIM To evaluate the feasibility and accuracy of tissue samples obtained using EUSFNA and EBUS-TBNA for molecular diagnosis of NSCLC.METHODS A total of 83 patients with NSCLC underwent molecular testing using tissues obtained from EUS-FNA or EBUS-TBNA at the Tianjin Medical University Cancer Hospital from January 2017 to June 2019.All enrolled patients underwent chest computed tomography or positron emission tomography/computed tomography prior to puncture.We detected abnormal expression of EGFR,KRAS,MET,HER2,ROS1 and anaplastic lymphoma kinase protein.Two patients failed to complete molecular testing due to insufficient tumor tissue.The clinical features,puncture records,molecular testing results and targeted treatment in the remaining 81 patients were summarized.RESULTS In a total of 99 tissue samples obtained from 83 patients,molecular testing was successfully completed in 93 samples with a sample adequacy ratio of 93.9%(93/99).Biopsy samples from two patients failed to provide test results due to insufficient tumor tissue.In the remaining 81 patients,62 cases(76.5%)were found to have adenocarcinoma,11 cases(13.6%)had squamous cell carcinoma,3 cases(3.7%)had adenosquamous carcinoma and 5 cases(6.2%)had NSCLC-not otherwise specified.The results of molecular testing showed EGFR mutations in 21 cases(25.9%),KRAS mutations in 9 cases(11.1%),ROS-1 rearrangement in 1 case(1.2%)and anaplastic lymphoma kinase-positive in 5 cases(6.2%).Twentyfour patients with positive results received targeted therapy.The total effectiveness rate of targeted therapy was 66.7%(16/24),and the disease control rate was 83.3%(20/24).CONCLUSION Tissue samples obtained by EUS-FNA or EBUS-TBNA are feasible for the molecular diagnosis of NSCLC and can provide reliable evidence for clinical diagnosis and treatment.

OBSERVATION ON THE EFFECT OF SHALLOW NEEDLING FOR TREATMENT OF PERIPHERAL FACIAL PARALYSIS IN 80 AFRICANS

This paper is a summary of 150 cases of facial paralysis in African black people treated with shallow needling and mild needling manipulation. After 3 courses of treatment, of the 80 cases in the shallow-needling group, 71 (88. 8% ) were cured, 5 (6. 3% ) had marked improvement, 3 (3. 7% ) had improvement and 1 (1. 2% ) failed; Of the 70 cases in traditional-needling group, 61 (87. 1 % ) were cured, 6 (8. 6% ) had evident improvement, 2 (2. 9% ) had improvement and 1 (1. 4 % ) had no striking change. Statistical analysis showed no significant difference between the two groups in the therapeutic effect (P >0. 5 ), indicating both the traditional needling method and shallow needling were effective in treatment of facial paralysis in black people. In addition, earlier treatment was very important in healing facial palsy; and the cure rate was higher in younger patients ard those with light severity.

TREATMENT OF 67 CASES OF GASTROPTOSIS WITH ELONGATED NEEDLE(芒针)

Sixty-seven patients with gastroptosis were treated by stimulating Guanmen (ST 22)and Taiyi (ST 23) acupoints with elongated needles, obtaining a satisfactory result. Of them, 52 caseswere cured, 7 cases markedly effective and 8 cases ineffective. The total effective rate was 88%.

CLINICAL OBSERVATION ON TREATMENT OF 198 CEREBRAL INFARCTION PATIENTS WITH OPPOSING AND NON-OPPOSING NEEDLING METHODS

198 cases of cerebral infarction diagnosed clinically.by means of CT scan wereselected, and the therapeutic effects obtained with the methods of opposing and non-opposing needlingwere compared, The primary points included Head-Linqi(GB 15) and Zhengying(GB 17) (penetra-tion needling), Fengchi(GB 20), Neiguan (PC 6), qnd Yinlingquan (SP 9). While the supplemen-tary points were Jiquan (HT 1 ), Xiaohai (SI 8), Huantiao (GB 30), Yinmen (BL 37), Sanyinjiao(SP 6), and Taixi (KI 3). It was found that the radical cure rate in the group treated with opposingneedling was 57%, while that in the group with non-opposipg needling was 34%. The difference oftherapeutic effects between the two groups was of statistical significance (P【0.01 ). It indicates thatopposing needling is superior to non-opposing needling in elevating cure rates and reducing sequelae.

CLINICAL ANALYSIS TO 74 CASES OF MENOPAUSAL SYNDROME TREATED WITH SIMPLE FIRE NEEDLE

In this paper,simple fire needle pricking the points of Du（Governor）and Ren（Conception）meridians was employed to treat 74 cases of menopausal syndrome.The result showedthat 41 cases were clinically cured,17 markedly improved,15 improved and 1 ineffective,with thetotal effective rate 87％.With the advantages of extensive materials used,simple manipulation andlarge variety of indications,this method is worthy to be popularized.

TREATMENT OF SCAPULOHUMERAL PERIARTHRITIS WITH WARM NEEDLING AND ACUPOINT INJECTION

The warm needling and acupoint injection of medicine are combined to treat scapulo-humeral periarthritis with marked analgesic effect because they have the efficacies of reinforcing defi-ciency and supporting the healthy energy,and eliminating the pathogens ans dredging the meridiansand collaterals.The quick and fair therapeutical effect will be obtained when the needling sensation ispropagated to the focus of disease.