Comparative Study between Intraoperative Frozen Section and Scrape Smear Cytology in the Diagnosis of Ovarian Neoplasm

Objective: The aim of this work is to compare between intraoperative frozen section and scrape smear cytology in the diagnosis of ovarian neoplasm. Method: This study was performed between March 2011 and March 2012, on 50 patients presented with ovarian mass. Gross examination of the tumor removed was done by inspection and palpation. The specimen was then cut with a sharp knife into two halves. The area was scraped with a sharp scalpel or the end of a glass slide, depending upon the type of tissue. A semifluid drop thus obtained was spread over a glass slide. One to four slides per case were taken from different representative areas. The slides were labelled and immediately put into 95% ethyl alcohol and stained with hematoxylin-eosin. The specimens were then fixed in formalin. Paraffin blocks of the sections were processed in the routine way and sections were stained with hematoxylin and eosin (H and E). Assessment of the overall accuracy of the intraoperative diagnosis was classified as concordant or discordant. Results: The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of scraping technique in the diagnosis of benign ovarian masses were 100%, 95.2%, 96.7%, 100% and 98% respectively. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of scraping technique in the diagnosis of border line ovarian masses were 100%, 93.4%, 25%, 100% and 94% respectively. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of scraping technique in the diagnosis of malignant ovarian masses were 80%, 100%, 100%, 88.2% and 92% respectively. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of frozen section in the diagnosis of benign ovarian masses were 100%, 100%, 100%, 100% and 100% respectively. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of frozen section in the diagnosis of borderline ovarian masses were 100%, 95.9%, 33.3%, 100% and 96% respectively. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of frozen section in the diagnosis of malignant ovarian masses were 90%, 100%, 100%, 93.8% and 96% respectively. Conclusion: Frozen section is more accurate than smear preparations in the intraoperative assessment of ovarian tumors in this study. However, the cytology preparations were helpful in supporting the histological diagnoses, and in some cases, provided additional useful information. Thus, cytology has a complementary role to frozen section in the intraoperative assessment of ovarian lesions. At the centers where the facilities of frozen section are not available, intraoperative scrape cytology is a useful tool for intraoperative diagnosis of tumor.

Clinical effect of scraping therapy in the treatment of knee osteoarthritis

Objective:The objective of this study is to investigate the effect of scraping therapy in the treatment of knee osteoarthritis.Materials and Methods:A total of eighty patients with knee osteoarthritis were assigned to the moxibustion group and the scraping therapy group according to the random numerical table method,with forty cases in each group.Patients in both two groups received functional exercise and moxibustion therapy,and those in the scraping therapy group were supplemented with scraping therapy.The serum indexes of interleukin‑1(IL‑1),IL‑6,tumor necrosis factor‑alpha(TNF‑α),and superoxide dismutase(SOD)were detected before and after the treatment.The clinical syndrome integral and Visual Analog Scale(VAS)on pain of patients were assessed.The clinical therapeutic efficacy was evaluated and compared between the two groups.Results:Patients in the scraping therapy group received better outcomes of serum IL‑1,IL‑6,TNF‑α,and SOD compared with those in the moxibustion group at 2 months after treatment(P<0.05).The scores of clinical syndrome integral and VAS on pain were decreased in two groups at 2 months after the treatment and were lower in the scraping therapy group than those in the moxibustion group(P<0.05).The overall effective rate in the scraping therapy group was higher than that in the control group(87.50%vs.67.50%,P<0.05).Conclusion:The scraping therapy is potentially effective to ameliorate the clinical symptom and pain degree of patients with knee osteoarthritis.

Ocular manifestations and SARS-CoV-2 detection in tears and conjunctival scrape from non-severe COVID-19 patients

AIM:To explore the ocular features of corona virus disease(COVID)-19 and severe acute respiratory syndrome coronavirus(SARS-CoV)-2 detection in tears and conjunctival scrapes in non-severe COVID-19 patients.METHODS:This is a multicenter observational clinical study with no intervention conducted from Jan 25th to March 1st,2020.Clinical data and samples of tears and conjunctival scraping were collected in consecutive laboratory-confirmed,non-severe COVID-19 patients from three hospitals.COVID-19 virus was analyzed by real-time reverse transcriptase polymerase chain reaction(RT-PCR)kits.RESULTS:Totally 255 laboratory-confirmed,non-severe COVID-19 patients were recruited for ocular manifestation investigation.Of them,54.9%were females,with a mean age of 49.4 y.None of the patients has evidence of uveitis;11 patients(4.3%)complained of mild asthenopia;2(0.8%)had mild conjunctival congestion and serous secretion.Twenty-five of them had performed tears and conjunctival scrape for COVID-19 virus detection,with 4 yield possible positive results in the nucleoprotein gene.One of them were asymptomatic with normal chest CT and positive pharyngeal swab result.CONCLUSION:Ocular manifestations are neither common nor specific in non-severe COVID-19 patients.Meanwhile,COVID-19 virus nucleotides can be detected in the tears and conjunctival scrape samples,warranting further research on the transmissibility by the ocular route.

Chemical Modification of Scraped Tires through Grafting with 2-Acrylamido-2-methylpropansulfonic Acid

Scrap vulcanized rubber is amongst a bigger waste polymers. It does not decompose easily owing to its cross linked structure. Modification of scrap tires powder by the grafting with 2-acrylamido-2-methylpropanesulfonic acid (AMPS) is described. The grafting is achieved through free radical initiation. The effects of different amount of monomer and initiator were examined. Also the influence of reaction time and temperature were investigated. The grafted waste rubber was characterized by FT/IR, SEM and DSC measurements. The proposed mechanism of the grafting reaction is discussed. From DSC and SEM studies of WR-g-AMPS compared with PAMPS and WR, the results show that the particle size and crystallinity were enhanced for the grafted copolymers. The obtained modified scraped tires will used as an ion exchanger for the future applications.

Advantages and Suggestions of Scraping to Promote Rehabilitation of COVID-19 Patients in Convalescence

Objective:To demonstrate the advantages of scraping in helping COVID-19 patients in convalescence,popularize scraping therapy among them and provide basis for the establishment of operation specification.Methods:Discuss the relationship between scraping and epidemic disease by reviewing the relevant scraping theory analysis,summarize the existing clinical studies and propose reference scheme for the treatment of COVID-19 patients in convalescence with respect to the related symptoms proving effective treatment of scraping on patients in convalescence.Results:Ancient healers used scraping to treat pestilence,and there have been many clinical trials and experiments for the treatment of convalescent symptoms related to scraping.Scraping also has the effect of improving immune function and antioxidation,which is feasible for the treatment of convalescent symptoms related to scraping.Conclusion:Scraping can effectively improve the clinical symptoms of COVID-19 convalescent patients,and it can be used as one of the external treatments for convalescent patients.It is recommended to promote scraping among the patients so that they can have self-intervention treatment.

Characteristics of Algal Succession Following Rock Scraping at Imwon Area in the East Coast of Korea

Abstract This study was conducted to clarify the characteristics high-pressure water sprayer in the period from June 2010 to April 2011 of algal succession following rock scraping using hoe or We divided the research area off the eastern coast of Korean near Imwon into 3 categories depending upon the severity of the barren ground, i.e., the urchin barren-affected, urchin bar- ren-ongoing and urchin barren-free areas. In April 2011, in the urchin barren-affected area with 25 seaweed species, the cover per- centage and importance value （IV） of erustose coralline algae were higher than those of other species. In the urchin barren-ongoing area with 33 seaweed species, crustose coralline algae （mean IV=62%） as well as Sargassum sp. （mean IV=28%）, and Gelidium amansii （mean IV= 19%） were observed following rock scraping. In the urchin barren-free area where seaweed communities were relatively abundant with 42 species, a variety of algal species including G. amansii （mean IV = 32%） underwent algal succession. Overall, it was observed that, as an aspect of algal succession, the weaker the barren ground severity was, the more frequent and di- verse the seaweeds were, and the more complex the succession pattern was in the study. As an aspect of recovering algal community, rock scraping using hoe was shown to be superior to the method using high-pressure water spraying. Therefore, we conclude that rock scraping using hoe is a very effective strategy for recovering the algal community in urchin barren-ongoing area.

Major physical but also psychological effects after pain relief from surgical scraping in patients with Achilles tendinopathy—A 1-year follow-up study

Treatment with Ultrasound (US) and Color Doppler (CD)-guided surgical scraping has shown good short-term clinical results in patients with chronic painful midportion Achilles tendinopathy. The objective was to prospectively follow the patients 1-year after surgery. Material: Sixty- four tendons in 47 patients (28 men and 19 women, mean age 52 (+/-12 years) on different activity levels) were in local anaestesia operated with US+CD-guided surgical scraping. In 43/64 tendons, there was also removal of the plantaris tendon. Methods: Questionnaires evaluating activity level, VAS for pain during activity, satisfaction with treatment result, and the SF-36 score (quality of life), were used before and 1-year after surgery. Results: At follow-up, the mean VAS for pain during activity had decreased from 62 (+/-20) before surgery to 15 (+/-15) after surgery (p < 0.001). All patients were satisfied with the result and had returned to full tendon loading activity. There were no complications. Both the physical and psychological parameters in the SF-36 score had improved significantly. Conclusions: For patients with chronic painful midportion Achilles tendinopathy, US+CD-guided surgical scraping, often combined with plantaris tendon removal, seems to be an efficient treatment method to recover physically and psychologically.

疏肝健脾汤联合刮痧治疗亚健康失眠临床观察

目的 观察疏肝健脾汤联合刮痧治疗亚健康失眠的临床效果。方法 将90例亚健康失眠患者随机分为治疗组和对照组,每组45例。治疗组采用疏肝健脾汤联合刮痧治疗,对照组口服艾司唑仑片。2组均连续治疗3周,观察2组患者的临床疗效。结果 治疗组总有效率92.86%(39/42)高于对照组的78.57%(33/42),差异有显著统计学意义(P<0.01)。治疗后,治疗组匹兹堡睡眠质量指数(PSQI)及中医证候积分均明显低于对照组(P<0.01)。结论 疏肝健脾汤联合刮痧治疗可有效改善亚健康失眠患者的失眠状态,提高其生活质量,值得临床进一步推广。

四妙勇安汤含漱配合刮痧治疗瘀热互结型小儿慢性扁桃体炎的效果观察

目的:探究四妙勇安汤含漱配合刮痧治疗小儿慢性扁桃体炎的效果。方法:前瞻性随机选取2022年3月—2023年3月在江阴市中医院进行诊治的80例慢性扁桃体炎患儿纳入研究。将其用随机数字表法分成对照组和观察组,每组40例。对照组予以生理盐水含漱治疗;观察组予以四妙勇安汤含漱配合刮痧治疗。比较两组临床疗效、临床症状体征积分、炎症水平、免疫水平及不良反应发生情况。结果:观察组临床疗效优于对照组(P<0.05)。治疗后,两组主要和次要症状体征积分、白细胞介素1β(IL-1β)、降钙素原(PCT)水平均下降(P<0.05),观察组低于对照组(P<0.01)。两组干扰素-γ(IFN-γ)、CD3^(+)、CD4^(+)/CD8^(+)水平均升高(P<0.05),观察组高于对照组(P<0.01)。两组不良反应比较差异无统计学意义(P>0.05)。结论:四妙勇安汤含漱配合刮痧治疗用于小儿慢性扁桃体炎,可明显提升疗效、改善临床症状和体征,减轻炎症反应,提升免疫功能,且用药较为安全。

基于气机升降理论的中医三联疗法治疗心肾不交型不寐的临床研究

目的评价基于气机升降理论的中医三联疗法治疗心肾不交型不寐患者的临床效果。方法选择2021年1-12月该院收治确诊的68例心肾不交型不寐患者为研究对象,随机分为治疗组和对照组,每组34例。治疗组采用中药内服+头部循经刮痧+引阳入阴气息引导推拿的中医三联法治疗;对照组采用口服艾司唑仑片治疗。比较两组疗效、睡眠质量[匹兹堡睡眠质量指数(PSQI)评分]、中医症候积分及神经递质[5-羟色胺(5-HT)、多巴胺(DA)]水平。结果治疗3周后,治疗组总有效率及5-HT水平均明显高于对照组(P<0.05),PSQI总评分、中医症候积分、DA水平均明显低于对照组(P<0.05)。结论中医三联疗法治疗心肾不交型不寐可显著改善患者的临床症状、神经递质水平,提高患者睡眠质量,值得推广应用。

需求侧岗位能力牵引的现代物流人才培养目标研究

近年来,物流行业在现代科技的驱动下飞速发展,行业需求与人才供给上的错位和人才短缺等问题逐渐显现。通过分析社会物流总额结构和就业人数分布揭示物流行业结构发展和人才需求趋势,通过爬取某招聘网站物流行业的招聘信息,挖掘物流行业不同职位类型对学历和任职要求的特点。结合产业能力模型设计物流行业岗位技能与岗位能力,通过建立岗位能力与人才培养内容之间的联系倒推人才培养目标,以期提高物流人才需求侧与供给侧的匹配度。

宫颈刮片BHLHE22/CDO1和COL2A1基因甲基化检测在早期子宫内膜癌筛查中的作用

目的探讨宫颈刮片BHLHE22/CDO1和COL2A1基因甲基化检测在早期子宫内膜癌筛查中的作用。方法选取徐州市妇幼保健院2022年2月—2024年5月行宫腔镜下诊断性刮宫排除子宫内膜病变的患者78例,妇科检查时进行宫颈刮片细胞采集,并进行BHLHE22/CDO1和COL2A1基因甲基化检测。同时收集患者的基本临床资料及三维能量多普勒超声下子宫内膜血流指数(FI)、血管化指数(VI)、血管化-血流指数(VFI)等资料。以宫腔镜手术获得的组织病理学结果为金标准,利用单因素logistic回归模型分析子宫内膜癌的影响因素,采用受试者工作特征(ROC)曲线下面积(AUC)分析相关基因甲基化检测联合或不联合子宫内膜血流指标对早期子宫内膜癌的筛查价值。结果患者年龄、体重指数、VI、FI、VFI、BHLHE22/CDO1基因甲基化高风险是子宫内膜癌的影响因素(P<0.05)。宫颈刮片相关基因甲基化检测筛查子宫内膜癌的AUC为0.926(0.846~1.000),其敏感度和特异度分别为90.48%、94.74%。子宫内膜血流指标VFI联合宫颈刮片相关基因甲基化检测可提高敏感度至100%,但特异度降至68.42%。结论宫颈刮片BHLHE22/CDO1和COL2A1基因甲基化检测筛查子宫内膜癌的准确性较高,联合子宫内膜血流指标可以增加筛查的敏感度,但也降低了筛查的特异度,增加了有创操作的风险。

1例肾阳虚型高血压患者的“双心护理”体会

本文总结了1例肾阳虚型高血压患者的“双心护理”体会。护理要点包括病情观察、血压监测、用药护理、中医特色护理等,并在此基础上给予心理评估、“双心”教育等干预措施。基于“双心护理”模式开展中西医结合护理,有助于改善患者症状,缓解心理压力,提高治疗依从性,促进患者康复。

不刮瓦轴承的两个基础理论及其实例计算分析

不刮瓦轴承在我国水泥工业应用中存在两个问题:一是对其形成楔形间隙的必要性和重要性的认识模糊甚至存在疑虑;二是担心管磨机主轴承球面瓦的巴氏合金轴瓦会被压坏。为消除当前不少人对不刮瓦轴承技术的疑虑和担心,通过对不刮瓦轴承两个基础理论及其实例计算进行分析,得出结论:(1)不刮瓦轴承即无负荷时轴颈与轴瓦接触角φ=0的滑动轴承,是一种当前最先进的滑动轴承;(2)在管磨机中,水泥磨机主轴承轴瓦的负荷是最大的或者说是最重的,经过实例计算表明其安全系数n最小者竟然大于10,表明巴氏合金轴瓦是绝对不会被压坏的。

皮部引流法治疗腰椎间盘突出症疗效观察

目的:观察皮部引流法治疗腰椎间盘突出症(LDH)的临床疗效。方法:将2022年10月—2023年10月在安徽中医药大学第二附属医院脑病三科就诊的确诊为LDH的60例患者随机分为皮部组和针刺组,每组30例。针刺组给予普通针刺治疗,皮部组给予皮部引流法治疗,采用刮痧疗法、刺血疗法联合“工”字形针刺法,2组均5次为1个疗程,共治疗2个疗程。采用视觉模拟评分法(VAS)和日本骨科协会腰椎功能障碍指数(JOA)评估两组患者治疗前后疼痛程度及腰椎功能,比较两组的总体疗效。结果:与治疗前比较,两组患者治疗后VAS评分明显降低,JOA评分明显升高,且皮部组VAS评分降低程度和JOA评分升高程度均高于针刺组,差异具有统计学意义(P<0.05);皮部组临床疗效明显优于针刺组,差异具有统计学意义(P<0.05)。结论:皮部引流法治疗LDH疗效显著。

数据抓取竞争互诉案件滥诉风险防范机制构建

因数据抓取引发的竞争互诉案件大量进入司法程序,引发滥诉的司法风险。既有司法案件表明,反不正当竞争与反垄断诉讼具有数量层失衡、主体层偏颇及结果层纠葛的特征,而现有滥诉机制鲜有基于风险防范视角,难以进行有效回应。目前竞争互诉司法理念较为陈旧,管辖制度规定略显滞后,大小平台诉讼博弈失衡,竞争诉讼负向激励配置匮乏。以贯彻新时代能动司法为原则,诉前应探索竞争诉讼集中管辖机制,诉中应进行数据抓取行为正当性的综合认定,并建立正负向相结合的激励制度体系,并树立现代化的司法理念。

循经刮痧联合五行音乐疗法对肝阳上亢型持续性姿势-感知性头晕的疗效观察

目的:探讨循经刮痧联合五行音乐疗法对肝阳上亢型持续性姿势-感知性头晕(PPPD)的疗效。方法:选择2022年9月—12月于我院就诊的66例肝阳上亢型PPPD病人作为研究对象,采用随机数字表法将病人分为观察组与对照组,各33例。对照组给予常规治疗及护理健康教育,观察组在对照组基础上采用循经刮痧联合五行音乐疗法。比较两组病人临床疗效、头晕程度、焦虑和抑郁情绪、中医证候评分。结果:观察组病人临床疗效优于对照组;观察组病人治疗后眩晕障碍量表、汉密尔顿焦虑量表、汉密尔顿抑郁量表及中医证候评分均低于治疗前及同期对照组,差异有统计学意义(P<0.05)。结论:循经刮痧联合五行音乐对肝阳上亢型PPPD病人临床疗效显著,可有效降低病人头晕程度、焦虑和抑郁情绪,减轻病人临床症状。

拨针疗法联合中药对腰椎间盘突出症患者术后神经根水肿时间、疼痛介质及血清miR-141-3p的影响

目的 观察拨针疗法联合消髓化核汤对腰椎间盘突出症患者臭氧射频消融术后神经根水肿时间、疼痛介质及血清mi R-141-3p的影响。方法 将92例行臭氧联合低温等离子射频消融术的腰椎间盘突出症患者随机分为消髓化核汤组和拨针联合组,每组46例。消髓化核汤组予消髓化核汤治疗,拨针联合组在消髓化核汤组基础上予拨针疗法治疗。观察两组神经根水肿消失时间及治疗前后中医证候积分、疼痛视觉模拟量表(visual analog scale, VAS)评分、炎症指标[微小核糖核酸-141-3p(miRNA-141-3p, miR-141-3p)、可溶性肿瘤坏死因子Ⅰ型受体(soluble tumor necrosis factor receptor typeⅠ, sTNFRⅠ)、白细胞介素-17(interleukin-17,IL-17)、磷脂酶A2(phospholipase A2, PLA2)]和疼痛介质指标[甲硫氨酸脑啡肽(methionine enkephalin,Met-EnK)、缓激肽(bradykinin,BK)、 5-羟色胺(5-hydroxy tryptamine,5-HT)、 6-酮前列腺素E1α(6-keto-prostaglandin E1α, 6-keto-PGE1α)]水平的变化,并比较两组临床疗效。结果 拨针联合组总有效率为97.8%,高于消髓化核汤组的82.6%(P<0.05)。治疗后,两组中医证候积分较治疗前降低(P<0.05),且拨针联合组低于消髓化核汤组(P<0.05)。治疗后,两组VAS评分较治疗前降低(P<0.05),拨针联合组低于消髓化核汤组(P<0.05)。拨针联合组患者神经根水肿消失时间短于消髓化核汤组(P<0.05)。治疗后,两组血清IL-17、PLA2、miR-141-3p含量较治疗前降低(P<0.05),且拨针联合组低于消髓化核汤组(P<0.05);两组血清s TNFRⅠ含量较治疗前升高(P<0.05),且拨针联合组高于消髓化核汤组(P<0.05)。治疗后,两组血清Met-En K含量较治疗前升高(P<0.05),且拨针联合组高于消髓化核汤组(P<0.05);两组血清6-keto-PGE1α、5-HT、BK含量较治疗前降低(P<0.05),且拨针联合组低于消髓化核汤组(P<0.05)。结论 拨针疗法联合消髓化核汤治疗可降低腰椎间盘突出症术后血清IL-17、PLA2、miR-141-3p水平,改善疼痛介质指标,促进神经根水肿消退,提升临床疗效。

耳部全息铜砭刮痧联合耳穴埋豆对社区肝阳上亢型高血压患者的干预效果评价

目的观察耳部全息铜砭刮痧联合耳穴埋豆对社区肝阳上亢型高血压患者的干预效果。方法选取2023年1月—6月厦门大学附属第一医院思明区中华道社区卫生服务中心参与慢病管理的肝阳上亢型高血压患者76例,按照随机数字表法分为对照组及研究组,各38例。对照组给予口服降压药物及常规高血压慢性病管理,研究组在对照组基础上采用耳部全息铜砭刮痧联合耳穴埋豆治疗。对比分析两组干预前后血压水平和中医症候总积分。结果干预后,两组患者收缩压和舒张压均较干预前下降,且研究组患者收缩压明显改善效果优于对照组,差异有统计学意义(P<0.01)。干预后,两组患者中医证候评分均较干预前降低,且研究组中医证候评分低于对照组,差异有统计学意义(P<0.01)。结论耳部全息铜砭刮痧联合耳穴埋豆对社区肝阳上亢型高血压患者的血压水平控制及中医症候的改善具有明确效果,对提高社区高血压慢性病管理质量具有重要促进作用,值得社区推广运用。

虎符铜砭刮痧联合PDCA循环护理在胃食管反流病患者中的应用

目的探讨对胃食管反流病患者实施虎符铜砭刮痧结合PDCA循环护理的效果。方法选择2020年6月至2022年6月期间南京市中医院收治的150例胃食管反流病患者,根据数字随机法将其分为对照组和观察组,每组75例。对照组给予PDCA循环护理进行干预,观察组给予PDCA循环护理结合虎符铜砭刮痧进行干预。比较2组患者干预前后的护理效果。结果干预4周及8周后,观察组的焦虑自评量表、抑郁自评量表和反流性疾病问卷评分均低于对照组,健康状况调查问卷评分均高于对照组(P均<0.05);干预4周及8周后,观察组的肿瘤坏死因子-α和超敏C反应蛋白水平均低于对照组,胃动素和胃泌素水平均高于对照组(P均<0.05);干预8周后,2组的上述评分和指标均优于干预前及干预4周后(P均<0.05)。结论对胃食管反流病患者应用虎符铜砭刮痧联合PDCA循环护理进行干预,能够有效缓解患者的临床症状和心理状态,改善其血清炎症因子和胃肠激素水平,且提升其生活质量。