Objective:To explore the clinical efficacy of Ningxin Tongluo Decoction(宁心通络汤)combined with Dapagliflozin in the treatment of type 2 diabetes mellitus complicated with ventricular premature beats.Methods:Ninety-t...Objective:To explore the clinical efficacy of Ningxin Tongluo Decoction(宁心通络汤)combined with Dapagliflozin in the treatment of type 2 diabetes mellitus complicated with ventricular premature beats.Methods:Ninety-two patients with type 2 diabetes mellitus complicated with ventricular premature beats in our hospital were randomly divided into control group(n=46)and observation group(n=46).The control group was treated with routine Western medicine,and the observation group was treated with Ningxin Tongluo Decoction on the basis of the control group.The clinical efficacy of the two groups before and after treatment,TCM syndrome score,blood glucose levels[fasting blood glucose(GLU),glycosylated hemoglobin(Hb A1c)],glucose metabolism levels[fasting insulin(FINS),insulin resistance index(HOMA-IR)],the number of ventricular premature beats detected by 24-hour ambulatory electrocardiogram,heart rate turbulence(HRT)[initial oscillation(TO),oscillation slope(TS)],and heart rate variability(HRV)standard deviation of two normal R-R intervals(SDNN),standard deviation of average normal R-R intervals every 5 minutes(SDANN)and root mean square of adjacent normal R-R intervals(RMSSD)were observed.Results:After treatment,the total effective rate of the observation group was 89.13%,significantly higher than that of the control group(73.91%),and the difference was statistically significant(P<0.05).Both groups could reduce TCM syndrome score,blood glucose level,glucose metabolism level,reduce the number of ventricular premature beats,improve HRT and HRV levels,and the observation group was superior to the control group,and the difference was statistically significant(P<0.05).Conclusion:Ningxin Tongluo Decoction combined with Dapagliflozin is effective in treating type 2 diabetes mellitus patients with ventricular premature beats.It can reduce blood glucose level,improve HRV and HRT,improve autonomic nerve function and exert antiarrhythmic effect.展开更多
Objective:To study the clinical effect of the Huagai Pingchuan decoction combined with Seretide in the treatment of asthma.Methods:138 cases of asthma patients in our hospital were separated into the control group and...Objective:To study the clinical effect of the Huagai Pingchuan decoction combined with Seretide in the treatment of asthma.Methods:138 cases of asthma patients in our hospital were separated into the control group and the experimental group.The control group was given Seretide alone,while the experimental group was treated with Huagai Pingchuan decoction combined with Seretide.Results:After treatment,the wheezing symptoms remission time of the experimental group was shorter than control group,the performance of serum inflammatory factors and lung function indexes were better than control group,P<0.05 with significant difference.Conclusion:Huagai Pingchuan decoction combined with Seretide is more effec-tive in the treatment of asthma.展开更多
文摘Objective:To explore the clinical efficacy of Ningxin Tongluo Decoction(宁心通络汤)combined with Dapagliflozin in the treatment of type 2 diabetes mellitus complicated with ventricular premature beats.Methods:Ninety-two patients with type 2 diabetes mellitus complicated with ventricular premature beats in our hospital were randomly divided into control group(n=46)and observation group(n=46).The control group was treated with routine Western medicine,and the observation group was treated with Ningxin Tongluo Decoction on the basis of the control group.The clinical efficacy of the two groups before and after treatment,TCM syndrome score,blood glucose levels[fasting blood glucose(GLU),glycosylated hemoglobin(Hb A1c)],glucose metabolism levels[fasting insulin(FINS),insulin resistance index(HOMA-IR)],the number of ventricular premature beats detected by 24-hour ambulatory electrocardiogram,heart rate turbulence(HRT)[initial oscillation(TO),oscillation slope(TS)],and heart rate variability(HRV)standard deviation of two normal R-R intervals(SDNN),standard deviation of average normal R-R intervals every 5 minutes(SDANN)and root mean square of adjacent normal R-R intervals(RMSSD)were observed.Results:After treatment,the total effective rate of the observation group was 89.13%,significantly higher than that of the control group(73.91%),and the difference was statistically significant(P<0.05).Both groups could reduce TCM syndrome score,blood glucose level,glucose metabolism level,reduce the number of ventricular premature beats,improve HRT and HRV levels,and the observation group was superior to the control group,and the difference was statistically significant(P<0.05).Conclusion:Ningxin Tongluo Decoction combined with Dapagliflozin is effective in treating type 2 diabetes mellitus patients with ventricular premature beats.It can reduce blood glucose level,improve HRV and HRT,improve autonomic nerve function and exert antiarrhythmic effect.
基金The Sixth Batch of national old TCM experts’academic experience inheritance project。
文摘Objective:To study the clinical effect of the Huagai Pingchuan decoction combined with Seretide in the treatment of asthma.Methods:138 cases of asthma patients in our hospital were separated into the control group and the experimental group.The control group was given Seretide alone,while the experimental group was treated with Huagai Pingchuan decoction combined with Seretide.Results:After treatment,the wheezing symptoms remission time of the experimental group was shorter than control group,the performance of serum inflammatory factors and lung function indexes were better than control group,P<0.05 with significant difference.Conclusion:Huagai Pingchuan decoction combined with Seretide is more effec-tive in the treatment of asthma.
文摘目的探讨活血通络汤在急性缺血性脑卒中(acute ischemic stroke,AIS)患者治疗中的效果及对其对中医证候、神经功能的影响。方法选取82例六安市中医院2021年1月—2022年1月收治的AIS患者作为研究对象,将其分为观察组(41例)和对照组(41例)(随机数字表法)。对照组接受常规西医治疗,观察组在对照组基础上接受活血通络汤治疗。两组治疗时间均为1个月。对两组治疗前后的美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)、蒙特利尔认知评估(Montreal Cognitive Assessment,MoCA)评分、中医证候积分、生活质量评分、全血高切黏度、全血低切黏度、血浆纤维蛋白原(fibrinogen,FIB)及D-二聚体(D-dimer,D-D)水平、血管内皮功能及治疗后的临床疗效进行比较。结果与观察组比较,对照组治疗后临床总有效率较低;治疗后两组中医证候各项评分、NIHSS评分、全血高切黏度、全血低切黏度、血浆FIB、D-D水平、血清内皮素-1(endothelin-1,ET-1)、血管性假血友病因子(von Willebrand factor,vWF)水平与治疗前比均降低,其中观察组低于对照组;治疗后两组生活质量评分、MoCA评分、血清一氧化氮(nitric oxide,NO)、血管舒张功能(flow-mediated dilation,FMD)水平与治疗前比均升高,组间进行比较,对照组较低(P<0.05)。结论活血通络汤应用于AIS患者可有效改善中医证候,利于神经功能和认知功能恢复,提高生活质量,调节血液状态和血管内皮功能,疗效显著。
