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基于BERTopic模型的国外信息资源管理研究进展分析 被引量:2
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作者 杨思洛 吴丽娟 《情报理论与实践》 CSSCI 北大核心 2024年第2期189-197,共9页
[目的/意义]文章从已有研究成果中提取主题,梳理主要研究方向,展示主题热度变化趋势,为了解和评估国外信息资源管理(IRM)研究发展现状与趋势提供参考。[方法/过程]采用新兴BERTopic模型对2013—2022年期间WoS数据库中IRM相关文献进行主... [目的/意义]文章从已有研究成果中提取主题,梳理主要研究方向,展示主题热度变化趋势,为了解和评估国外信息资源管理(IRM)研究发展现状与趋势提供参考。[方法/过程]采用新兴BERTopic模型对2013—2022年期间WoS数据库中IRM相关文献进行主题提取与识别,结合相关主题词及主题距离划分研究方向,并利用动态主题模型揭示国外IRM领域的演变过程。[结果/结论]国外IRM近10年的研究可分为59个主题,可归纳为信息技术及应用、企业信息管理、图书馆管理与服务、健康信息管理、信息用户与服务、IRM基本理论与方法、文献计量与评价7个方向。大多数主题的研究热度变化偏向稳定的趋势,数字化建设、开放数据等部分主题热度逐渐上涨,而外包、知识管理等少数主题热度退却。 展开更多
关键词 国外信息资源管理 主题模型 BERtopic 研究主题 研究进展
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类Chen-Qi混沌系统的固定时间自适应同步控制
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作者 王院生 《动力学与控制学报》 2024年第7期80-86,共7页
类Chen-Qi四维混沌系统的渐近稳定控制的同步误差不能在有限时间内收敛到零,有限时间控制的同步误差收敛到零的状况与初值有关.因此,本文应用固定时间控制技术,设计了自适应控制器和参数估计律,试图使得驱动系统与同类型的参数未知的响... 类Chen-Qi四维混沌系统的渐近稳定控制的同步误差不能在有限时间内收敛到零,有限时间控制的同步误差收敛到零的状况与初值有关.因此,本文应用固定时间控制技术,设计了自适应控制器和参数估计律,试图使得驱动系统与同类型的参数未知的响应系统在固定时间内达到同步,完成了理论证明.应用数值仿真考察同步误差收敛到零的状况.选取不同参数值,不同状态初值,考察状态时程图、同步误差曲线等.结果表明:混沌运动时,固定时间内同步误差收敛到零的效果较好,与状态初值无关,收敛时间符合理论计算值;周期运动时,固定时间内前三个状态的同步误差收敛到零的效果较好,收敛时间符合理论计算值,但第四个状态的同步误差的收敛时间不符合理论计算值,其原因是系统存在的三次非线性项的不平衡、不匹配. 展开更多
关键词 类Chen-qi超混沌系统 固定时间同步 自适应控制器 同步误差 数值仿真
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基于BERTopic模型的网络暴力事件衍生舆情探测 被引量:2
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作者 胡凯茜 李欣 王龙腾 《情报杂志》 CSSCI 北大核心 2024年第7期146-153,共8页
[研究目的]在海量用户生成内容中及时探测和剖析网络暴力事件的衍生舆情能够为舆情事件链的演化分析、同类舆情的研判介入、衍生事件的监测预警提供理论支持。[研究方法]使用BERTopic模型对短文本内容主题建模并采用聚类的方式展示主题... [研究目的]在海量用户生成内容中及时探测和剖析网络暴力事件的衍生舆情能够为舆情事件链的演化分析、同类舆情的研判介入、衍生事件的监测预警提供理论支持。[研究方法]使用BERTopic模型对短文本内容主题建模并采用聚类的方式展示主题的潜在层次结构。根据词向量余弦相似度设计主题衍生度的计量算法,同时融合词共现网络在文档-词语层面信息捕捉的优势以及桑基图直观演示舆情演化过程的特点,衡量主题间的影响力与衍生关系。[研究结论]在开源数据集下多组主题模型的对照实验中,BERTopic模型在短文本建模以及下游任务的平均得分提高2.13%。在网络暴力热点事件的应用实例中,多维细粒度分析与交互式可视化方法可达到直观展示暴力事件的主题聚类、词义关联与演化态势的效果,实现网络暴力事件衍生舆情的探测与分析。 展开更多
关键词 网络舆情 网络暴力 衍生舆情 舆情监测 短文本 主题建模 BERtopic模型
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基于BERTopic算法的引文主题实证分析——以一篇高被引诺贝尔生理学或医学奖论文为例
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作者 郭倩影 赵丹群 《情报理论与实践》 CSSCI 北大核心 2024年第10期183-189,182,共8页
[目的/意义]引文主题识别/分析(CTR/CTA)是引文内容分析(CCA)的一项重要研究议题,通过对引文语料中蕴涵主题信息的识别和提取,可望为论文学术贡献评价、知识扩散及演化分析等问题的解决提供新的研究思路。[过程/方法]以一篇高被引诺贝... [目的/意义]引文主题识别/分析(CTR/CTA)是引文内容分析(CCA)的一项重要研究议题,通过对引文语料中蕴涵主题信息的识别和提取,可望为论文学术贡献评价、知识扩散及演化分析等问题的解决提供新的研究思路。[过程/方法]以一篇高被引诺贝尔生理学或医学获奖关键论文为例,采用BERTopic算法对其引文句语料进行主题识别,并对识别出的引文主题展开多个维度的分析与讨论。[结果/结论]对高被引论文开展引文主题识别分析,有助于更全面细致地揭示其学术贡献内容及演化趋势;BERTopic算法能较好识别案例文献的多个引文主题,且不同引文主题的施引文献特征分布不尽相同;对引文主题重要性、演化趋势及其与原文主题差异性的分析,能多维度刻画研究同行对案例文献学术贡献的认识,表明CTR/CTA研究对学术论文评价具有深入探索价值。 展开更多
关键词 BERtopic算法 引文主题识别 引文主题分析 引文内容分析 学术论文评价
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Analyzing topics in social media for improving digital twinning based product development
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作者 Wenyi Tang Ling Tian +1 位作者 Xu Zheng Ke Yan 《Digital Communications and Networks》 SCIE CSCD 2024年第2期273-281,共9页
Digital twinning enables manufacturers to create digital representations of physical entities,thus implementing virtual simulations for product development.Previous efforts of digital twinning neglect the decisive con... Digital twinning enables manufacturers to create digital representations of physical entities,thus implementing virtual simulations for product development.Previous efforts of digital twinning neglect the decisive consumer feedback in product development stages,failing to cover the gap between physical and digital spaces.This work mines real-world consumer feedbacks through social media topics,which is significant to product development.We specifically analyze the prevalent time of a product topic,giving an insight into both consumer attention and the widely-discussed time of a product.The primary body of current studies regards the prevalent time prediction as an accompanying task or assumes the existence of a preset distribution.Therefore,these proposed solutions are either biased in focused objectives and underlying patterns or weak in the capability of generalization towards diverse topics.To this end,this work combines deep learning and survival analysis to predict the prevalent time of topics.We propose a specialized deep survival model which consists of two modules.The first module enriches input covariates by incorporating latent features of the time-varying text,and the second module fully captures the temporal pattern of a rumor by a recurrent network structure.Moreover,a specific loss function different from regular survival models is proposed to achieve a more reasonable prediction.Extensive experiments on real-world datasets demonstrate that our model significantly outperforms the state-of-the-art methods. 展开更多
关键词 Digital twinning Product development topic analysis Social media
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A Video Captioning Method by Semantic Topic-Guided Generation
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作者 Ou Ye Xinli Wei +2 位作者 Zhenhua Yu Yan Fu Ying Yang 《Computers, Materials & Continua》 SCIE EI 2024年第1期1071-1093,共23页
In the video captioning methods based on an encoder-decoder,limited visual features are extracted by an encoder,and a natural sentence of the video content is generated using a decoder.However,this kind ofmethod is de... In the video captioning methods based on an encoder-decoder,limited visual features are extracted by an encoder,and a natural sentence of the video content is generated using a decoder.However,this kind ofmethod is dependent on a single video input source and few visual labels,and there is a problem with semantic alignment between video contents and generated natural sentences,which are not suitable for accurately comprehending and describing the video contents.To address this issue,this paper proposes a video captioning method by semantic topic-guided generation.First,a 3D convolutional neural network is utilized to extract the spatiotemporal features of videos during the encoding.Then,the semantic topics of video data are extracted using the visual labels retrieved from similar video data.In the decoding,a decoder is constructed by combining a novel Enhance-TopK sampling algorithm with a Generative Pre-trained Transformer-2 deep neural network,which decreases the influence of“deviation”in the semantic mapping process between videos and texts by jointly decoding a baseline and semantic topics of video contents.During this process,the designed Enhance-TopK sampling algorithm can alleviate a long-tail problem by dynamically adjusting the probability distribution of the predicted words.Finally,the experiments are conducted on two publicly used Microsoft Research Video Description andMicrosoft Research-Video to Text datasets.The experimental results demonstrate that the proposed method outperforms several state-of-art approaches.Specifically,the performance indicators Bilingual Evaluation Understudy,Metric for Evaluation of Translation with Explicit Ordering,Recall Oriented Understudy for Gisting Evaluation-longest common subsequence,and Consensus-based Image Description Evaluation of the proposed method are improved by 1.2%,0.1%,0.3%,and 2.4% on the Microsoft Research Video Description dataset,and 0.1%,1.0%,0.1%,and 2.8% on the Microsoft Research-Video to Text dataset,respectively,compared with the existing video captioning methods.As a result,the proposed method can generate video captioning that is more closely aligned with human natural language expression habits. 展开更多
关键词 Video captioning encoder-decoder semantic topic jointly decoding Enhance-TopK sampling
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Pain perception enhancement in consecutive secondeye phacoemulsification cataract surgeries under topical anesthesia
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作者 Jia-Wei Luo Yan-Hua Chen +3 位作者 Jian-Feng Yu Yi-Xun Chen Min Ji Huai-Jin Guan 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第8期1510-1518,共9页
Cataract is the main cause of visual impairment and blindness worldwide while the only effective cure for cataract is still surgery.Consecutive phacoemulsification under topical anesthesia has been the routine procedu... Cataract is the main cause of visual impairment and blindness worldwide while the only effective cure for cataract is still surgery.Consecutive phacoemulsification under topical anesthesia has been the routine procedure for cataract surgery.However,patients often grumbled that they felt more painful during the second-eye surgery compared to the first-eye surgery.The intraoperative pain experience has negative influence on satisfaction and willingness for second-eye cataract surgery of patients with bilateral cataracts.Intraoperative ocular pain is a complicated process induced by the nociceptors activation in the peripheral nervous system.Immunological,neuropsychological,and pharmacological factors work together in the enhancement of intraoperative pain.Accumulating published literatures have focused on the pain enhancement during the secondeye phacoemulsification surgeries.In this review,we searched PubMed database for articles associated with pain perception differences between consecutive cataract surgeries published up to Feb.1,2024.We summarized the recent research progress in mechanisms and interventions for pain perception enhancement in consecutive secondeye phacoemulsification cataract surgeries.This review aimed to provide novel insights into strategies for improving patients’intraoperative experience in second-eye cataract surgeries. 展开更多
关键词 ocular pain cataract surgery topical anesthesia intraoperative experience second-eye phacoemulsification
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The Essential Role of Zheng Qi in Promoting Health: From the Perspective of Chinese Medicine and Modern Medicine
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作者 Kam Ming Ko Hoi Yan Leung 《Chinese Medicine》 CAS 2024年第2期27-33,共7页
The concept of Zheng Qi in traditional Chinese medicine (TCM) refers to the vital energy produced by the interaction of Yin and Yang forces in the body. Zheng Qi performs two main functions: Wei Qi (defensive Qi), whi... The concept of Zheng Qi in traditional Chinese medicine (TCM) refers to the vital energy produced by the interaction of Yin and Yang forces in the body. Zheng Qi performs two main functions: Wei Qi (defensive Qi), which shields the body from external pathogens, and Ying Qi (nutritive Qi), which sustains the internal organs and enhances their functionality. In TCM, Chinese tonifying herbs can help restore the balance of Yin/Yang and Qi/Blood function in visceral organs (i.e., optimal physiological functions), thereby fostering the efficient production of Zheng Qi and enhancing health. To ensure the quality of Chinese herbal products, functional assays to measure Yin/Yang, Qi/Blood functions, and Zheng Qi production should be implemented. The efficacy of Yang and Qi herbs can be evaluated by their ability to increase mitochondrial ATP in cultured mouse cardiomyocytes, while Yin and Blood herbs are tested through their immunostimulatory effects on antigen-induced T/B cell proliferation in mouse splenocytes and the production of erythropoietin/nitric oxide in hepatocytes/vascular endothelial cells, respectively. Additionally, Zheng Qi’s effect can be gauged by examining natural killer cell activity and antigen-induced T/B cell proliferation in mice ex vivo. These assays act as biomarkers for assessing the quality and effectiveness of herbal health products within TCM theory. 展开更多
关键词 Traditional Chinese Medicine Zheng qi IMMUNITY Biomarkers Functional Assays
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TCM-HIN2Vec:A strategy for uncovering biological basis of heart qi deficiency pattern based on network embedding and transcriptomic experiment
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作者 Lihong Diao Xinyi Fan +5 位作者 Jiang Yu Kai Huang Edouard C.Nice Chao Liu Dong Li Shuzhen Guo 《Journal of Traditional Chinese Medical Sciences》 CAS 2024年第3期264-274,共11页
Objective:To elucidate the biological basis of the heart qi deficiency(HQD)pattern,an in-depth understanding of which is essential for improving clinical herbal therapy.Methods: We predicted and characterized HQD patt... Objective:To elucidate the biological basis of the heart qi deficiency(HQD)pattern,an in-depth understanding of which is essential for improving clinical herbal therapy.Methods: We predicted and characterized HQD pattern genes using the new strategy,TCM-HIN2Vec,which involves heterogeneous network embedding and transcriptomic experiments.First,a heterogeneous network of traditional Chinese medicine(TCM)patterns was constructed using public databases.Next,we predicted HQD pattern genes using a heterogeneous network-embedding algorithm.We then analyzed the functional characteristics of HQD pattern genes using gene enrichment analysis and examined gene expression levels using RNA-seq.Finally,we identified TCM herbs that demonstrated enriched interactions with HQD pattern genes via herbal enrichment analysis.Results: Our TCM-HIN2Vec strategy revealed that candidate genes associated with HQD pattern were significantly enriched in energy metabolism,signal transduction pathways,and immune processes.Moreover,we found that these candidate genes were significantly differentially expressed in the transcriptional profile of mice model with heart failure with a qi deficiency pattern.Furthermore,herbal enrichment analysis identified TCM herbs that demonstrated enriched interactions with the top 10 candidate genes and could potentially serve as drug candidates for treating HQD.Conclusion: Our results suggested that TCM-HIN2Vec is capable of not only accurately identifying HQD pattern genes,but also deciphering the basis of HQD pattern.Furthermore our finding indicated that TCM-HIN2Vec may be further expanded to develop other patterns,leading to a new approach aimed at elucidating general TCM patterns and developing precision medicine. 展开更多
关键词 qi deficiency pattern Heart failure Biological basis Network embedding Transcriptome
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Exploring the therapeutic potential of Qi Teng Mai Ning recipe in ischemic stroke and vascular cognitive impairment
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作者 Jia-Yan Yao Yue-Lan Yang +1 位作者 Wei-Jian Chen Hai-Ying Fan 《Traditional Medicine Research》 2024年第10期21-35,共15页
Background:This study aims to explore the therapeutic effects of the Qi Teng Mai Ning recipe on ischemic stroke and vascular cognitive impairment through its potential to modulate cellular autophagy,with a focus on id... Background:This study aims to explore the therapeutic effects of the Qi Teng Mai Ning recipe on ischemic stroke and vascular cognitive impairment through its potential to modulate cellular autophagy,with a focus on identifying its active ingredients and their target proteins.Methods:The study began with the identification of active ingredients in the Qi Teng Mai Ning recipe.It proceeded to screen the gene expression omnibus database for ischemic stroke and vascular cognitive impairment-associated differentially expressed mRNAs and to identify cellular autophagy-related proteins via the Human Autophagy Database.These proteins were annotated with Gene Ontology and Kyoto Encyclopedia of Genes and Genomes functions and subjected to molecular docking with the recipe’s core active ingredients.In vitro cell experiments were conducted on hypoxic HT22 cells,involving CCK8 assay,lentiviral transfection to silence autophagy related 9B(ATG9B),immunofluorescence staining,and qPCR validation to investigate the effects of the recipe on autophagy.Results:The analysis identified 104 active ingredients targeting 408 proteins and forming a complex ingredient-target network.Intersecting 55 ischemic stroke-related and 909 vascular cognitive impairment-related differentially expressed mRNAs revealed 14 co-expressed mRNAs.Molecular docking showed quercetin,kaempferol,myrcene,and conferone as key ingredients targeting autophagy-related proteins.Cellular experiments indicated that the recipe significantly enhanced cell viability under hypoxic conditions,reduced apoptosis,and modulated the expression of autophagy-related factors,thereby decreasing apoptosis rates in HT22 cells.Conclusion:The Qi Teng Mai Ning recipe offers protective effects against ischemic stroke and vascular cognitive impairment by modulating autophagy-related proteins.Its efficacy highlights the potential of traditional Chinese medicine in treating these conditions,though further research is needed to fully understand its mechanisms and clinical applications. 展开更多
关键词 qi Teng Mai Ning recipe AUTOPHAGY ischemic stroke vascular cognitive impairment traditional Chinese medicine
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Pharmacological Investigation on the Qi-Invigorating Action of Schisandrin B: Effects on Mitochondrial ATP Generation in Multiple Tissues and Innate/Adaptive Immunity in Mice
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作者 Hoi Yan Leung Suen Chit Sze Kam Ming Ko 《Chinese Medicine》 CAS 2024年第2期15-26,共12页
Schisandrae Fructus, containing schisandrin B (Sch B) as its main active component, is recognized in traditional Chinese medicine (TCM) for its Qi-invigorating properties in the five visceral organs. Our laboratory ha... Schisandrae Fructus, containing schisandrin B (Sch B) as its main active component, is recognized in traditional Chinese medicine (TCM) for its Qi-invigorating properties in the five visceral organs. Our laboratory has shown that the Qi-invigorating action of Chinese tonifying herbs is linked to increased mitochondrial ATP generation and an enhancement in mitochondrial glutathione redox status. To explore whether Sch B can exert Qi-invigorating actions across various tissues, we investigated the effects of Sch B treatment on mitochondrial ATP generation and glutathione redox status in multiple mouse tissues ex vivo. In line with TCM theory, which posits that Zheng Qi generation relies on the Qi function of the visceral organs, we also examined Sch B’s impact on natural killer cell activity and antigen-induced splenocyte proliferation, both serving as indirect measures of Zheng Qi. Our findings revealed that Sch B treatment consistently enhanced mitochondrial ATP generation and improved mitochondrial glutathione redox status in mouse tissues. This boost in mitochondrial function was associated with stimulated innate and adaptive immune responses, marked by increased natural killer cell activity and antigen-induced T/B cell proliferation, potentially through the increased generation of Zheng Qi. 展开更多
关键词 Zheng qi Schisandrin B MITOCHONDRIA ATP Generation Glutathione Redox Innate Immunity Adaptive Immunity Natural Killer Cell Activity Splenocyte Proliferation
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基于BERTopic模型的数字政府治理领域的主题识别与内容分析
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作者 高凡 徐思佳 《情报理论与实践》 CSSCI 北大核心 2024年第8期95-106,共12页
[目的/意义]在信息技术创新、政府数字化转型的背景下,中国学术界输出的“数字政府治理”相关研究体量较大,现阶段亟待对其进行科学整理和综述概览,以回应“政府治理现代化”目标对理论研究的新要求。[方法/过程]以2011-2023年间中国知... [目的/意义]在信息技术创新、政府数字化转型的背景下,中国学术界输出的“数字政府治理”相关研究体量较大,现阶段亟待对其进行科学整理和综述概览,以回应“政府治理现代化”目标对理论研究的新要求。[方法/过程]以2011-2023年间中国知网数据库收录的有关数字政府治理研究的1829篇文献为数据来源,借助深度学习模型BERTopic和文献计量法CiteSpace相互验证分析数字政府治理领域的研究阶段、研究关键词、研究热点主题及内容等,使得结果具有高准确性和强解释性,以科学有效地探测主题取向及特征,展望数字政府治理领域的未来研究方向。[结果/结论]中国数字政府治理研究在过去的10年间发展迅猛,已成为学者探索的热点论域;现有文献研究热点整体上聚焦于价值导向、治理模式进化、技术工具嵌入;重点主题关注的是“政府数据开放共享研究”“基于数字技术的政务服务改革研究”“城乡场域下的数字化治理研究”“数字政府治理水平的评估研究”及“数字化转型下具体治理领域的实践研究”。未来,数字政府治理仍然是一个具有持续性拓展空间的研究领域,将逐步实现数字政府治理的更广场域触达、精准滴灌、多项学科融合和技术实用主义。 展开更多
关键词 数字政府 政府治理 主题识别 BERtopic 主题模型
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基于Citation Topic的领域期刊主题演化研究——以行为医学为例
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作者 张琳 孙奥琦 高岩 《科技传播》 2024年第18期66-69,共4页
基于论文层面的Citation Topic分类体系,通过测度行为医学领域SCI及SSCI期刊引文主题变动情况,展现国际行为医学领域研究重点以及相关支撑学科的演化。
关键词 Citation topic 期刊 研究主题 行为医学
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Clinical Observation of the Hot and Humid Compress Therapy of Traditional Chinese Medicine in the Treatment of Qi Stagnation and Blood Stasis Type of Lumbar Disc Herniation
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作者 Hailin Song Kui Xu +3 位作者 Hong Zhu Zengwu Xu Peng Li Runkai Wang 《Open Journal of Orthopedics》 2024年第7期312-324,共13页
Background: Although a number of studies have reported that the hot and humid compress from traditional Chinese medicine (TCM) is effective in treating lumbar disc herniation (LDH) with qi stagnation and blood stasis,... Background: Although a number of studies have reported that the hot and humid compress from traditional Chinese medicine (TCM) is effective in treating lumbar disc herniation (LDH) with qi stagnation and blood stasis, clinical evidence is limited. Objective: The purpose of this study is to provide high-quality evidence to support the effectiveness of the traditional Chinese hot and humid compress in the treatment of LDH with qi stagnation and blood stasis. Methods: From October 2021 to November 2023, 86 patients with LDH of qi stagnation and blood stasis type were recruited in our hospital and divided into a control (n = 43) and an observation group (n = 43) according to the random number table method. The control group was given routine clinical treatment, and the observation group was treated with the hot and humid compress therapy for two weeks. The visual analogue scale (VAS) score, Japanese Orthopaedic Association (JOA) score, TCM syndrome score, serum interleukin-6 (IL-6), serum interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were observed and compared between the two groups before and after treatment, and the clinical efficacy of the two groups was evaluated. Results: After treatment, the VAS score, TCM symptom score, and serum IL-6, IL-1β, and TNF-α levels decreased in both groups (P P P P P Conclusions: The hot and humid compress of traditional Chinese medicine can effectively relieve pain, restore lumbar function, improve TCM syndromes, reduce the level of inflammatory factors, and have a curative effect in treating LDH. 展开更多
关键词 Chinese Medicine Hot and Humid Compress Lumbar Disc Herniation qi Stagnation and Blood Stasis Type TCM Symptom Score Clinical Efficacy
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基于BERTopic的中药治疗眼科疾病的处方用药规律分析
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作者 卢昕怡 李弘辰 +1 位作者 吴双 罗杰 《浙江临床医学》 2024年第6期899-901,共3页
目的分析中医药治疗眼科疾病的处方用药规律,探讨治疗眼科疾病的更多潜在配伍组合。方法收集眼科专家门诊的中医处方并整理筛选,采用Python 3.9.10中BERTopic算法对复发性虹膜睫状体炎的所有处方进行分析,得到药物关键词聚类组合;采用SP... 目的分析中医药治疗眼科疾病的处方用药规律,探讨治疗眼科疾病的更多潜在配伍组合。方法收集眼科专家门诊的中医处方并整理筛选,采用Python 3.9.10中BERTopic算法对复发性虹膜睫状体炎的所有处方进行分析,得到药物关键词聚类组合;采用SPSS 25.0对中药处方数据进行层次聚类,比较两种方法的优劣和药物配伍组合的挖掘效果。结果采用BERTopic算法得到核心药物关键词组合累计2种,包括酒地龙、土茯苓、大青叶、葎草等;应用层次聚类得到的药物组合包括葎草、土茯苓、菝葜等。应用BERTopic技术的算法具有不易受噪声数据影响、提高聚类效率、增强对于处方文本语义理解等诸多优势。结论使用基于BERTopic技术的算法在寻找疾病潜在中药配伍中表现良好,潜力较大,能为眼科疾病的中药配伍组合提供更多参考方向。 展开更多
关键词 数据挖掘 用药规律 眼科疾病 BERtopic模型
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Network pharmacology-based exploration of molecular mechanisms underlying therapeutic effects of Jianpi Huatan Quyu recipe on chronic heart failure with spleen Qi deficiency syndrome
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作者 Si-Qi Li Dong-Yu Min +7 位作者 Jun-Wen Jiang Xiao-Ying Li Xu-Na Yang Wen-Bo Gu Jia-Hui Jiang Li-Hao Chen Han Nan Ze-Yu Chen 《World Journal of Cardiology》 2024年第7期422-435,共14页
BACKGROUND Chronic heart failure is a complex clinical syndrome.The Chinese herbal compound preparation Jianpi Huatan Quyu recipe has been used to treat chronic heart failure;however,the underlying molecular mechanism... BACKGROUND Chronic heart failure is a complex clinical syndrome.The Chinese herbal compound preparation Jianpi Huatan Quyu recipe has been used to treat chronic heart failure;however,the underlying molecular mechanism is still not clear.AIM To identify the effective active ingredients of Jianpi Huatan Quyu recipe and explore its molecular mechanism in the treatment of chronic heart failure.METHODS The effective active ingredients of eight herbs composing Jianpi Huatan Quyu recipe were identified using the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform.The target genes of chronic heart failure were searched in the Genecards database.The target proteins of active ingredients were mapped to chronic heart failure target genes to obtain the common drugdisease targets,which were then used to construct a key chemical componenttarget network using Cytoscape 3.7.2 software.The protein-protein interaction network was constructed using the String database.Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed through the Metascape database.Finally,our previously published relevant articles were searched to verify the results obtained via network pharmacology.RESULTS A total of 227 effective active ingredients for Jianpi Huatan Quyu recipe were identified,of which quercetin,kaempferol,7-methoxy-2-methyl isoflavone,formononetin,and isorhamnetin may be key active ingredients and involved in the therapeutic effects of TCM by acting on STAT3,MAPK3,AKT1,JUN,MAPK1,TP53,TNF,HSP90AA1,p65,MAPK8,MAPK14,IL6,EGFR,EDN1,FOS,and other proteins.The pathways identified by KEGG enrichment analysis include pathways in cancer,IL-17 signaling pathway,PI3K-Akt signaling pathway,HIF-1 signaling pathway,calcium signaling pathway,cAMP signaling pathway,NF-kappaB signaling pathway,AMPK signaling pathway,etc.Previous studies on Jianpi Huatan Quyu recipe suggested that this Chinese compound preparation can regulate the TNF-α,IL-6,MAPK,cAMP,and AMPK pathways to affect the mitochondrial structure of myocardial cells,oxidative stress,and energy metabolism,thus achieving the therapeutic effects on chronic heart failure.CONCLUSION The Chinese medicine compound preparation Jianpi Huatan Quyu recipe exerts therapeutic effects on chronic heart failure possibly by influencing the mitochondrial structure of cardiomyocytes,oxidative stress,energy metabolism,and other processes.Future studies are warranted to investigate the role of the IL-17 signaling pathway,PI3K-Akt signaling pathway,HIF-1 signaling pathway,and other pathways in mediating the therapeutic effects of Jianpi Huatan Quyu recipe on chronic heart failure. 展开更多
关键词 Jianpi Huatan Quyu recipe Traditional Chinese medicine Chronic heart failure Data mining Network pharmacology BIOINFORMATICS Spleen qi deficiency syndrome
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基于BERTopic主题建模的延时现场救护研究趋势与热点分析
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作者 辛然 李雪玉 房玉丽 《军事护理》 CSCD 北大核心 2024年第9期50-53,58,共5页
目的分析2009~2024年间国际延时现场救护领域的文献,探究主要研究主题及其发展趋势,以期为未来救护策略提供理论支持。方法系统检索PubMed、Embase、Web of Science和中国知网等数据库,筛选并纳入283篇相关文献。运用BERTopic主题建模... 目的分析2009~2024年间国际延时现场救护领域的文献,探究主要研究主题及其发展趋势,以期为未来救护策略提供理论支持。方法系统检索PubMed、Embase、Web of Science和中国知网等数据库,筛选并纳入283篇相关文献。运用BERTopic主题建模技术对文献进行主题识别和关键词分析,并进行可视化展示。结果当前研究主要聚焦在“急救策略研究”“智能技术与信息管理”“实战应用”与“政策与理论研究”等4个方面,预测这些领域将持续成为研究热点。结论国际延时现场救护研究正处于快速发展阶段,建议未来研究深入重点领域,开发有效的救护策略,以提升救治效率和伤员生存率。 展开更多
关键词 延时现场救护 主题建模 研究热点
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Exploring the Effect of Qi Cross-Shaped Moxibustion on the Recovery of Gastrointestinal Function after Hip Fracture in the Elderly
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作者 Huiping Li 《Journal of Clinical and Nursing Research》 2024年第7期140-145,共6页
Objective:To explore the effect of Qi cross-shaped moxibustion on the recovery of gastrointestinal function in elderly hip fracture patients after surgery.Methods:62 elderly hip fracture surgery patients were selected... Objective:To explore the effect of Qi cross-shaped moxibustion on the recovery of gastrointestinal function in elderly hip fracture patients after surgery.Methods:62 elderly hip fracture surgery patients were selected as the base analysis sample,enrolled in January 2023-May 2024,and divided into an observation group(n=31)and a control group(n=31)using the digital table random draw scheme.The patients in the control group underwent conventional dietary intervention,and the patients in the observation group underwent Qi cross-shaped moxibustion intervention,comparing the gastrointestinal function recovery time and quality of life scores(PAC-QOL)of patients with constipation between the two groups.Results:The gastrointestinal function recovery time of the observation group was lower than that of the control group(P<0.05);the PAC-QOL score of the observation group was lower than that of the control group after the intervention(P<0.05).Conclusion:Qi cross-shaped moxibustion can shorten the recovery time of gastrointestinal function and improve the quality of life of elderly hip fracture patients after surgery,and it has the value of promotion and application. 展开更多
关键词 qi cross-shaped moxibustion Hip fracture Gastrointestinal function
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Observation on the Nursing Effect of Ginger Moxibustion on Gastrointestinal Symptoms in Patients with Heart Failure Due to Yang Qi Deficiency
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作者 Yijing Wang 《Journal of Clinical and Nursing Research》 2024年第6期135-141,共7页
Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi defi... Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi deficiency type)accompanied by gastrointestinal symptoms who were admitted to the hospital between January 2023 and January 2024 were selected and divided into 43 cases in each group by random number table grouping;Group I implemented integrated care,while Group II adopted conventional care.The indicators of care were compared between the two groups.Results:After the nursing care,the digestive symptom scores of Group I were lower than those of Group I,and the psychological scores were lower than those of Group II(P<0.05).Conclusion:Ginger moxibustion can improve gastrointestinal symptoms and enhance the psychological health of patients with heart failure(yang qi deficiency type)with gastrointestinal symptoms. 展开更多
关键词 Ginger moxibustion Yang qi deficiency Heart failure Gastrointestinal symptoms
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A study on the treatment of chloasma with moxibustion based on the theory of“Yang transforming Qi,and Yin shaping”
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作者 Mi Yang Hong-Yi Lan +2 位作者 Hong Wu Xu Wang Xin-Ju Li 《Clinical Research Communications》 2024年第3期23-28,共6页
Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of... Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of the strengths of TCM in treating diseases is holistic regulation.The theory of“Yang transforming Qi,and Yin shaping”implies a strong holistic view.Chloasma,one of the common skin diseases,seriously affects the physical and mental health of patients due to its unclear etiology,difficult treatment and easy recurrence.The occurrence and development of chloasma are closely related to internal organs.This paper is based on the theory of internal meridian,“Yang transforming Qi,and Yin shaping”which attaches importance to the concept of“Yang Qi”,from a new understanding of the pathogenesis etiology of chloasma.Methods:The author believes that the incidence of the disease is the deficiency of Yang Qi,which can’t promote the movement of Qi and blood to nourish the face,resulting in tangible material condensation,so proposes that this disease needs to be promoted by Yang transforming Qi and warm to dissipate.Moxibustion belongs to the fire,and its warming effect can dissipate the tangible evil.Results:Combined with clinical practice and the theory of internal meridian,the author elaborated that moxibustion is one of the effective methods for treating chloasma,which provides a new way of thinking for the treatment of chloasma.Conclusion:“Yang Transforming Qi and Yin shaping”can be used to guide the treatment of chloasma. 展开更多
关键词 Yang Transforming qi and Yin shaping MOXIBUSTION CHLOASMA
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