The Significance of Constructing TCM Psychosomatic Medicine from the Holistic View of the Unity of Nature and Man

With the development of medical technology, the problem of fragmentation of medical research has become increasingly prominent, and a series of iatrogenic diseases, drug-induced diseases and drug toxicity and side effects have resulted in an increase in the number of diseases. In the face of these problems, the medical concept has been re-examined and re-thought. The concept of the holistic view of the unity of nature and man in traditional Chinese medicine has certain enlightenment for dealing with the problems in the current medical development. Based on the holistic view of the unity of nature and man, the overall connection between human’s heart and body and nature is explained, and the further construction of TCM psychosomatic medicine is conducive to guiding the diagnosis and treatment of clinical diseases, and providing new enlightenment for the current medical concept thinking and clinical disease research.

Path Integral Quantization of Non-Natural Lagrangian

Path integral technique is discussed using Hamilton Jacobi method. The Hamilton Jacobi function of non-natural Lagrangian is obtained using separation of variables method. This function makes an important role in path integral quantization. The path integral is obtained as integration over the canonical phase space coordinates, which contains the generalized coordinate q and the generalized momentum p. One illustrative example is considered to explain the application of our formalism.

Protecting Our Common Homestead:A Comparative Study on Attitudes Towards Man and Nature in Chinese and the Western Culture

In light of increasingly worsening environmental pollution,this paper,through comparing different attitudes towards the relationship between man and nature in Chinese and the western culture,points out rebuilding a harmonious relationship between man and nature is the common object of human being,and appeals to people to shake off man-centered thinking pattern,and to treat nature as our friend.

Chinese and Western Philosophy on Man and Nature

Throughout history, various cultures have sought to understand the relationship between man and nature. Therefore, the relation-ship between man and nature is one of the basic problems to be solved. The aim of this paper is to compare the differences between the philosophical reactions to the relationship between man and nature in Chinese and Western cultures, the reasons related to the differences and its present developments.

Man and Nature in Chinese and Western Traditions

The Chinese conception of "oneness with man and heaven"and the Western tradition of man’s separation from nature accompanied by a subject- object dichotomy are the cores of each culture, which largely decides the discrepancy in various aspects of the Chinese and Western ways. To have an embedded and penetrating idea about the differences between the two cultures, it is necessary to gain sufficient knowledge of man- nature relation in dominant Chinese and Western conceptions. This paper aims to explore this issue from the perspective of Taoism and Confucianism in Chinese context, and ancient Greek and Hebraic heritage and modern mechanical view in Western tradition.

The Thought of the Oneness Between Man and Nature in Walden

From the view of the ecological theory, this paper tries to analyze that Thoreau uses Chinese traditional philosophical thought--- the oneness of man and nature to deal with the relationship of human beings and the nature in Walden.

The Nature of Man and His Place in the Universe——A Comparative Study of An Essay on Man and Gulliver’s Travels

As leading figures in English literature during the Neoclassical period,Alexander Pope and Jonathan Swift both showed great concern with the nature of man and his place in the Great Chain of Being.They both emphasized the irreplaceable role of reason in guiding man in his self-positioning in the universe,and pointed out the tragic,pathetic,or detestable fall man was vulnerable to in case of violating the law of nature.Pope attached more importance to setting right man' s position as against God and beast,while Swift showed more interest in the chain of being within the human society;Pope kept warning man against his pride and possible ruin as a result of his ambition,while Swift worried more about man' s degradation due to loss of reason.

On the Theory of Harmonious Co-existence between Man and Nature by Marx and Engels

Marx and Engles believed that man and nature develop harmoniously, when the activities of man constitute the content of nature, which is changed constantly because of the activities of man. Marx and Engles also pointed out the duarity of the conquest, change and influence exerted on nature by man. On one hand, it can improve people's riving conditions and make people free from the enslavement of the nature. On the other hand,it may also lead to excessively snatching and wrecking nature, then make the deterioration of the environment and ecology out of balance. They also, from the technical angle of ecology, put forward the concrete measures to realize the harmonious symbiosis of man and nature in the development of economy. They also believed that only when socialism or communism is realized, can the conciliation of mankind and nature be realized finally.Marx and Engle's theory of harmonious symbiosis of man and nature is of great theoretical directive significance for us to insist on the scientific development view.

Multi‑omics integration identifies regulatory factors underlying bovine subclinical mastitis

Background Mastitis caused by multiple factors remains one of the most common and costly disease of the dairy industry.Multi-omics approaches enable the comprehensive investigation of the complex interactions between mul-tiple layers of information to provide a more holistic view of disease pathogenesis.Therefore,this study investigated the genomic and epigenomic signatures and the possible regulatory mechanisms underlying subclinical mastitis by integrating RNA sequencing data(mRNA and lncRNA),small RNA sequencing data(miRNA)and DNA methylation sequencing data of milk somatic cells from 10 healthy cows and 20 cows with naturally occurring subclinical mastitis caused by Staphylococcus aureus or Staphylococcus chromogenes.Results Functional investigation of the data sets through gene set analysis uncovered 3458 biological process GO terms and 170 KEGG pathways with altered activities during subclinical mastitis,provided further insights into subclin-ical mastitis and revealed the involvement of multi-omics signatures in the altered immune responses and impaired mammary gland productivity during subclinical mastitis.The abundant genomic and epigenomic signatures with sig-nificant alterations related to subclinical mastitis were observed,including 30,846,2552,1276 and 57 differential methylation haplotype blocks(dMHBs),differentially expressed genes(DEGs),lncRNAs(DELs)and miRNAs(DEMs),respectively.Next,5 factors presenting the principal variation of differential multi-omics signatures were identified.The important roles of Factor 1(DEG,DEM and DEL)and Factor 2(dMHB and DEM),in the regulation of immune defense and impaired mammary gland functions during subclinical mastitis were revealed.Each of the omics within Factors 1 and 2 explained about 20%of the source of variation in subclinical mastitis.Also,networks of impor-tant functional gene sets with the involvement of multi-omics signatures were demonstrated,which contributed to a comprehensive view of the possible regulatory mechanisms underlying subclinical mastitis.Furthermore,multi-omics integration enabled the association of the epigenomic regulatory factors(dMHBs,DELs and DEMs)of altered genes in important pathways,such as‘Staphylococcus aureus infection pathway’and‘natural killer cell mediated cyto-toxicity pathway’,etc.,which provides further insights into mastitis regulatory mechanisms.Moreover,few multi-omics signatures(14 dMHBs,25 DEGs,18 DELs and 5 DEMs)were identified as candidate discriminant signatures with capac-ity of distinguishing subclinical mastitis cows from healthy cows.Conclusion The integration of genomic and epigenomic data by multi-omics approaches in this study provided a better understanding of the molecular mechanisms underlying subclinical mastitis and identified multi-omics candidate discriminant signatures for subclinical mastitis,which may ultimately lead to the development of more effective mastitis control and management strategies.

Modern Annotation on Marx's Theory of Man and Nature

Marx's theory of man and nature is an indispensable important constituent of Marx's society development theory. The humanity is not always there,and they come from natural world and are long-term development products of the nature. Man has the undeniable dependence on the nature,but this kind of dependence is not the negative adaptation and is that the humanity has the huge motility to the nature. It should correctly process the relation between man and nature,and realize positive cycle and coordinated development between natural ecology and human society. It has the significant theory value and the practical significance for human society's sustainable development to grasp and comprehend scientific connotation of Marx's theory of man and nature.

Passive Cooldown Performance of Integral Pressurized Water Reactor

The design of an integral pressurized water reactor (IPWR) focuses on enhancing the safety and reliability of the reactor by incorporating a number of inherent safety features and engineered safety features. However, the characteristics of passive safety systems for the marine reactors are quiet different from those for the land nuclear power plant because of the more formidable and dangerous operation environments of them. This paper presents results of marine black out accident analyses. In the case of a transient, the passive residual heat removal system (PRHRS) is designed to cool the reactor coolant system (RCS) from a normal operation condition to a hot shutdown condition by a natural circulation, and the shutdown cooling system (SCS) is designed to cool the primary system from a hot shutdown condition to a refueling condition by a forced circulation. A realistic calculation has been carried out by using the RELAP5/MOD3.4 code and a sensitivity analysis has been performed to evaluate a passive cooldown capability. The results of the accident analyses show that the reactor coolant system and the passive residual heat removal system adequately remove the core decay heat by a natural circulation.

Spatiotemporal variations of ecosystem services and driving factors in the Tianchi Bogda Peak Natural Reserve of Xinjiang,China

Nature reserves play a significant role in providing ecosystem services and are key sites for biodiversity conservation.The Tianchi Bogda Peak Natural Reserve(TBPNR),located in Xinjiang Uygur Autonomous Region,China,is an important ecological barrier area in the temperate arid zone.The evaluation of its important ecosystem services is of great significance to improve the management level and ecological protection efficiency of the reserve.In the present study,we assessed the spatiotemporal variations of four ecosystem services(including net primary productivity(NPP),water yield,soil conservation,and habitat quality)in the TBPNR from 2000 to 2020 based on the environmental and social data using the Integrated Valuation of Ecosystem Services and Trade-offs(InVEST)model.In addition,the coldspot and hotspot areas of ecosystem services were identified by hotspot analysis,and the trade-off and synergistic relationships between ecosystem services were analyzed using factor analysis in a geographic detector.During the study period,NPP and soil conservation values in the reserve increased by 48.20%and 25.56%,respectively;conversely,water yield decreased by 16.56%,and there was no significant change in habitat quality.Spatially,both NPP and habitat quality values were higher in the northern part and lower in the southern part,whereas water yield showed an opposite trend.Correlation analysis revealed that NPP showed a synergistic relationship with habitat quality and soil conservation,and exhibited a trade-off relationship with water yield.Water yield and habitat quality also had a trade-off relationship.NPP and habitat quality were affected by annual average temperature and Normalized Difference Vegetation Index(NDVI),respectively,while water yield and soil conservation were more affected by digital elevation model(DEM).Therefore,attention should be paid to the spatial distribution and dynamics of trade-off and synergistic relationships between ecosystem services in future ecological management.The findings of the present study provide a reference that could facilitate the sustainable utilization of ecosystem services in the typical fragile areas of Northwest China.

Integrated management of natural resources in the Ecuador Highlands

The Andean region of Ecuador is characterized by extreme poverty caused by low agricultural productivity, limited off-farm opportunities, and lack of access to markets. Poverty is related to degradation of natural resources as lagging agricultural productivity leads to incursions into fragile areas and use of erosive farming techniques on steeply sloped hillsides. Food production in fragile areas degrades soil and water resources, contributes to deforestation and loss of biodiversity, and reduces productive potential over time. This article discusses an agricultural development project designed to reduce the long-term downward development spiral in a watershed in Bolivar, Ecuador. The applied research program began with analysis of the state of soil resources, water, and biodiversity in the Chimbo sub-watershed. This information was used to design a plan with the input of local stakeholders to introduce environmentally friendly farming practices, soil and water conservation techniques, and various institutional innovations to promote resource conservation. This adaptive management program has been a solid success. This article describes the project, the challenges it faced, and how the process of adaptive management led to consensus among stakeholders about the appropriateness of sustainable management practices. We show how implementation of enhanced management practices contribute to reduced environmental vulnerability and improved welfare.

Man and Nature——A Comparative Study of Views Towards Nature Between Chinese and Westerners

Chinese and westerners, due to the different natural environment they are situated in and further due to different backgroundin history, economy, politics and culture, have made for differences in their ways of seeing nature and the relationship between man andnature, which substantially influences how Chinese and western societies proceed. This is a study on the similarities and differences onpeople's views of nature in the past and the reasons behind the differences.

RELATIONSHIP BETWEEN MAN AND NATURE IN TRADITIONAL HUMAN RIGHTS CONCEPTS OF CHINA AND WEST

As the process of economic globalization gathers momentum, dialogue between different cultures has become extremely important. There should be dialogue between the Chinese and Western cultures under the principle of equality and mutual respect and understanding to increase consensus for mutual development.

Harmony between man and nature:the base for the harmonious society

The harmony between man and nature is the base for the harmonious society. It is determined by the eco-ruleand eco-economic rule. Human being should not violate the eco-rule. However, human being can make eco-systemsupply suit economic growth and its speed through systematical innovation and restriction of human economic activityand choice. Through technological innovation, efficiency satisfaction of unit resource can be increased; structure andfunction of eco-system can be perfected; supply capability of eco-system can be improved. To build the harmonioussociety, human should consider the reasonable distribution of limited resources from two sides. The first one is that theutilization of two functions of resource supply and pollution purification to nature should not exceed its special supplycapability formed under its special structure and function states, i.e. harmony between man and nature. The second sideis human being should think over the reasonable and effective distribution of limited resources in economic society, i.e.harmony between human beings and society. The reasonable economic activity of human being is the key to the harmo-nious development of man and nature.