Adjustment of Administrative Divisions and Upgrading of Industrial Structure in Hefei Metropolitan Area:Taking"Partitions of Chaohu"as a Quasi-natural Experiment

Administrative regions are an important environment for the operation of China's market economy.The relevant economic subjects cannot predict the policy of adjustment of administrative divisions and carry out conscious migration behavior,adjustment of administrative divisions can be regarded as a quasi-natural experiment.The three cities of Hefei,Wuhu,and Ma'anshan,which are directly related to the adjustment of the administrative division of Chaohu,are taken as the treatment group,and the seven adjacent cities of Lu'an,Huainan,Chuzhou,Bengbu,Anqing,Chizhou,and Tongling are taken as the control group.Differences-in-Differences method and relevant control variables affecting the upgrading of industrial structure are used to test.The test results show that"Partitions of Chaohu"has a significant industrial structure upgrading effect by promoting the optimization of spatial layout,the cross-regional flow of production factors and the effective management of Chaohu Lake Basin.At the same time,the increase of total retail sales of consumer goods,urban fixed assets investment,public utility expenses in science,education,culture and health,and population plays a significant positive role in promoting the upgrading of industrial structure,while foreign direct investment plays a certain inhibition role in the upgrading of industrial structure.In order to meet the ever-developing space demands and enhance the impact on surrounding areas,the Hefei metropolitan area should be driven by technological innovation,strengthen the integration of industrial chains,improve the business environment and transportation network,and continuously promote the upgrading of industrial structure and the formation and development of new productive forces.

Modeling the Seasonal Temperature from Hourly Data: Seasonal Divisions

In this work, we present a general theoretical study leading to analytical expression of the seasonal temperature at the near surface that is expected to evaluate any area seasonal temperature of the world using the least square method to fit the hourly data to the theoretical curve of the temperature. It is shown that the temperature is globally the result of two contributions: the contribution of the revolution movement of the terrestrial globe on its elliptical orbit around the sun, the contribution of the spin-orbit coupling for the rotation movement of the terrestrial globe around its polar axis and its revolution movement. The orbital behavior of the temperature is used to find the seasonal divisions of the climate for the local area considered. The whole expression of the temperature is very useful for the meteorological needs. The contribution of the human activities and natural instabilities are the results of discrepancies which increase errors (standard deviations).

Efficacy and safety of Tripterygium wilfordii glycosides tablets combined with Western medicine for patients with rheumatic immune diseases

BACKGROUND Rheumatic immune diseases are a group of chronic inflammatory diseases charac-terized by joint and systemic multi-organ involvement,including rheumatoid arthritis,systemic lupus erythematosus,and Sjogren’s syndrome,among others.The pathogenesis of these diseases is related to the abnormal activation and regulatory imbalance of the immune system.The prevalence and morbidity of rheumatic immune diseases are high,imposing a significant burden on patients'quality of life and socio-economic costs.Currently,the treatment of rheumatic immune diseases mainly relies on Western medicine,such as non-steroidal anti-inflammatory drugs,glucocorticoids,disease-modifying antirheumatic drugs,and biologics.However,the therapeutic effects of Western medicine are not ideal,some patients poorly respond or are resistant to Western medicine,and long-term use often causes various adverse reactions.AIM To systematically evaluate the efficacy and safety of Tripterygium wilfordii gly-cosides tablets combined with Western medicine in the treatment of patients with rheumatic immune diseases.METHODS This study conducted a meta-analysis to systematically evaluate the efficacy and safety of Tripterygium wilfordii glycosides tablets combined with Western medicine for patients with rheumatic immune diseases.Chinese and English databases were searched for randomized controlled trials(RCTs)on the treatment of rheumatic immune diseases with Tripterygium wilfordii glycosides tablets combined with Western medicine.The quality of the included studies was assessed using the Cochrane risk of bias assessment tool.Meta-analysis was performed using RevMan 5.4 software.RESULTS The meta-analysis included 11 RCTs involving 1026 patients with rheumatic immune diseases.The combined treatment significantly reduced the risk of disease recurrence(relative risk=1.07,95%confidence interval:1.01-1.15,P<0.05)and showed no significant heterogeneity(I2=0%,P=0.53),indicating that Tripterygium wilfordii glycosides tablets combined with Western medicine is an effective method to reduce the possibility of postoperative recurrence in patients with rheumatic immune diseases.However,due to the limited number and quality of the studies included,these results should be interpreted with caution.CONCLUSION Tripterygium wilfordii glycosides tablets combined with Western medicine is an effective and safe treatment option for patients with rheumatic immune diseases and can be considered a clinical choice.However,more high-quality research is needed to validate this conclusion and provide more solid evidence for clinical practice.

Burden of mental disorders and risk factors in the Western Pacific region from 1990 to 2021

BACKGROUND The burden of mental disorders(MD)in the Western Pacific Region(WPR)re-mains a critical public health concern,with substantial variations across demogra-phics and countries.AIM To analyze the burden of MD in the WPR from 1990 to 2021,along with associated risk factors,to reveal changing trends and emerging challenges.METHODS We used data from the Global Burden of Disease 2021,analyzing prevalence,incidence,and disability-adjusted life years(DALYs)of MD from 1990 to 2021.Statistical methods included age-standardisation and uncertainty analysis to address variations in population structure and data completeness.RESULTS Between 1990 and 2021,the prevalence of MD rose from 174.40 million cases[95%uncertainty interval(UI):160.17-189.84]to 234.90 million cases(95%UI:219.04-252.50),with corresponding DALYs increasing from 22.8 million(95%UI:17.22-28.79)to 32.07 million(95%UI:24.50-40.68).During this period,the burden of MD shifted towards older age groups.Depressive and anxiety disorders were predominant,with females showing higher DALYs for depressive and anxiety disorders,and males more affected by conduct disorders,attention-deficit hyperactivity disorder,and autism spectrum disorders.Australia,New Zealand,and Malaysia reported the highest burdens,whereas Vietnam,China,and Brunei Darussalam reported the lowest.Additionally,childhood sexual abuse and bullying,and intimate partner violence emerged as significant risk factors.CONCLUSION This study highlights the significant burden of MD in the WPR,with variations by age,gender,and nation.The coronavirus disease 2019 pandemic has exacerbated the situation,emphasizing the need for a coordinated response.

Cohort study on the treatment of BRAF V600E mutant metastatic colorectal cancer with integrated Chinese and western medicine

BACKGROUND Patients with BRAF V600E mutant metastatic colorectal cancer(mCRC)have a low incidence rate,poor biological activity,suboptimal response to conventional treatments,and a poor prognosis.In the previous cohort study on mCRC conducted by our team,it was observed that integrated Chinese and Western medicine treatment could significantly prolong the overall survival(OS)of patients with colorectal cancer.Therefore,we further explored the survival benefits in the population with BRAF V600E mutant mCRC.AIM To evaluate the efficacy of integrated Chinese and Western medicine in the treatment of BRAF V600E mutant metastatic colorectal cancer.METHODS A cohort study was conducted on patients with BRAF V600E mutant metastatic colorectal cancer admitted to Xiyuan Hospital of China Academy of Chinese Medical Sciences and Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region from January 2016 to December 2022.The patients were divided into two cohorts.RESULTS A total of 34 cases were included,with 23 in Chinese-Western medicine cohort(cohort A)and 11 in Western medicine cohort(cohort B).The median overall survival was 19.9 months in cohort A and 14.2 months in cohort B,with a statistically significant difference(P=0.038,hazard ratio=0.46).The 1-3-year survival rates were 95.65%(22/23),39.13%(9/23),and 26.09%(6/23)in cohort A,and 63.64%(7/11),18.18%(2/11),and 9.09%(1/11)in cohort B,respectively.Subgroup analysis showed statistically significant differences in median OS between the two cohorts in the right colon,liver metastasis,chemotherapy,and first-line treatment subgroups(P<0.05).CONCLUSION Integrated Chinese and Western medicine can prolong the survival and reduce the risk of death in patients with BRAF V600E mutant metastatic colorectal cancer,with more pronounced benefits observed in patients with right colon involvement,liver metastasis,combined chemotherapy,and first-line treatment.

Seismo-tectonic divisions of strong earthquakes with M_s≥7.0 and their tectonic geomorphology along Xianshuihe-Xiaojiang fault zone

Seismo-tectonic areas of historical strong earthquakes with MS(7 along Xianshuihe-Xiaojiang fault zone are divided, and their individual fault-pattern and tectonic geomorphology are analyzed. Those strong-earthquake areas are located in some special parts of the fault zone, where the major branch-faults of the fault zone form left stepping, parallel, and fork-like patterns. In the strong-earthquake areas structurally complicated basins are developed, such as pull-apart basins in fork-like area, in double stepping area, and in stepping and fork-like areas.

"Made in China" Reflects Low Added-value in Global Industrial Divisions

The Belle Corporation is a Chinese domestic shoe maker and seller. It also belongs to an industry that has come to be representative of the ubiquitous "Made in China" label. One of the main reasons the company is favored by global investors is due to its unique business pattern-a pattern that sets manufacturing as its base and is active in exploring industrial chain downstream links and establishing its own individual retail channels. Ever since its first inception in the stock market, Belle has set out to acquire several upstream manufacturing companies, indicating its desire for increasing channel terminals. Using a vertically integrated competition strategy, Belle stands out amongst its rivals as being particularly successful in the non-mainstream manufacturing sector. Consequently, its business practices can be used as a model for other domestic manufacturing companies in their efforts to meet the challenges posed by globalization.

A Physics-informed Deep-learning Intensity Prediction Scheme for Tropical Cyclones over the Western North Pacific

Accurate prediction of tropical cyclone(TC)intensity is challenging due to the complex physical processes involved.Here,we introduce a new TC intensity prediction scheme for the western North Pacific(WNP)based on a time-dependent theory of TC intensification,termed the energetically based dynamical system(EBDS)model,together with the use of a long short-term memory(LSTM)neural network.In time-dependent theory,TC intensity change is controlled by both the internal dynamics of the TC system and various environmental factors,expressed as environmental dynamical efficiency.The LSTM neural network is used to predict the environmental dynamical efficiency in the EBDS model trained using besttrack TC data and global reanalysis data during 1982–2017.The transfer learning and ensemble methods are used to retrain the scheme using the environmental factors predicted by the Global Forecast System(GFS)of the National Centers for Environmental Prediction during 2017–21.The predicted environmental dynamical efficiency is finally iterated into the EBDS equations to predict TC intensity.The new scheme is evaluated for TC intensity prediction using both reanalysis data and the GFS prediction data.The intensity prediction by the new scheme shows better skill than the official prediction from the China Meteorological Administration(CMA)and those by other state-of-art statistical and dynamical forecast systems,except for the 72-h forecast.Particularly at the longer lead times of 96 h and 120 h,the new scheme has smaller forecast errors,with a more than 30%improvement over the official forecasts.

SOME EQUAL DIVISIONS ON ORDERED TREE SET

We say a divisien (S = SA or SB, g) is equal if it divides set S into two subsets SA and SB satisfying f (SA) = f (SB), where f is som attribute function on these sets and SA or SB need not be empty. In the present paper, we have obtained some equal divisions on set of ordered tree with n modes: two equal divisions on tree set; two equal divisions on node set; two divisions on leaf set, one is equal, another one is ''asymptotically'' equal. We conclude that, ordered tree set is on its good behavior in equal dividing.

Quantitative effect of kerogen type on the hydrocarbon generation potential of Paleogene lacustrine source rocks,Liaohe Western Depression,China

Kerogen types exert a decisive effect on the onset and capacity of hydrocarbon generation of source rocks.Lacustrine source rocks in the Liaohe Western Depression are characterized by thick deposition,high total organic carbon(TOC)content,various kerogen types,and a wide range of thermal maturity.Consequently,their hydrocarbon generation potential and resource estimation can be misinterpreted.In this study,geochemical tests,numerical analysis,hydrocarbon generation kinetics,and basin modeling were integrated to investigate the differential effects of kerogen types on the hydrocarbon generation potential of lacustrine source rocks.Optimized hydrocarbon generation and expulsion(HGE)models of different kerogen types were established quantitatively upon abundant Rock-Eval/TOC/vitrinite reflectance(R_(o))datasets.Three sets of good-excellent source rocks deposited in the fourth(Es4),third(Es3),and first(Es1)members of Paleogene Shahejie Formation,are predominantly types I-II_(1),II_(1)-II_(2),and II-III,respectively.The activation energy of types I-II_(2)kerogen is concentrated(180-230 kcal/mol),whereas that of type III kerogen is widely distributed(150-280 kcal/mol).The original hydrocarbon generation potentials of types I,II_(1),II_(2),and III kerogens are 790,510,270,and 85 mg/g TOC,respectively.The Ro values of the hydrocarbon generation threshold for type I-III source rocks gradually increase from 0.42%to 0.74%,and Ro values of the hydrocarbon expulsion threshold increase from 0.49%to 0.87%.Types I and II_(1)source rocks are characterized by earlier hydrocarbon generation,more rapid hydrocarbon expulsion,and narrower hydrocarbon generation windows than types II_(2)and III source rocks.The kerogen types also affect the HGE history and resource potential.Three types(conventional,tight,and shale oil/gas)and three levels(realistic,expected,and prospective)of hydrocarbon resources of different members in the Liaohe Western Depression are evaluated.Findings suggest that the Es3 member has considerable conventional and unconventional hydrocarbon resources.This study can quantitatively characterize the hydrocarbon generation potential of source rocks with different kerogen types,and facilitate a quick and accurate assessment of hydrocarbon resources,providing strategies for future oil and gas exploration.

Natural gas exploration potential and favorable targets of Permian Fengcheng Formation in the western Central Depression of Junggar Basin,NW China

Based on the organic geochemical data and the molecular and stable carbon isotopic compositions of natural gas of the Lower Permian Fengcheng Formation in the western Central Depression of Junggar Basin,combined with sedimentary environment analysis and hydrocarbon-generating simulation,the gas-generating potential of the Fengcheng source rock is evaluated,the distribution of large-scale effective source kitchen is described,the genetic types of natural gas are clarified,and four types of favorable exploration targets are selected.The results show that:(1)The Fengcheng Formation is a set of oil-prone source rocks,and the retained liquid hydrocarbon is conducive to late cracking into gas,with characteristics of high gas-generating potential and late accumulation;(2)The maximum thickness of Fengcheng source rock reaches 900 m.The source rock has entered the main gas-generating stage in Penyijingxi and Shawan sags,and the area with gas-generating intensity greater than 20×10^(8) m^(3)/km^(2) is approximately 6500 km^(2).(3)Around the western Central Depression,highly mature oil-type gas with light carbon isotope composition was identified to be derived from the Fengcheng source rocks mainly,while the rest was coal-derived gas from the Carboniferous source rock;(4)Four types of favorable exploration targets with exploration potential were developed in the western Central Depression which are structural traps neighboring to the source,stratigraphic traps neighboring to the source,shale-gas type within the source,and structural traps within the source.Great attention should be paid to these targets.

The Epigenetic“Dance”of Cell Divisions

The tango of life begins with the very first cell division.New research reveals that to dance their way through development,dividing cells must pass along not just DNA but molecular“memories”that guide their destinies.When this handoff gets fumbled,the dance falls apart.

Division and correlation of Yixian Formation in western Liaoning,China

The Yixian Formation is a series of volcanic-sedimentary rocks in Biepiao area of Liaoning Province. It is mainly composed of basic and intermediate-basic volcanic lava,pyroclasts and terrestrial sedimentary rocks. Based on the regularity of volcanic activity,the Yixian Formation was divided by the present authors into four members in ascending order:the first member is of basal conglomerate,basic and intermediate-basic volcanic rocks; the second member is of lake phrase sedimentary rocks,or in another word,precious fossil-rich sedimentary beds; the third is of basic volcanic rocks; and the fourth is of upper conglomerate. Field mapping and comprehensive study also indicate that there are abundant vertebrate fossils (mainly of Psittacosaurus) in the first member of the Yixian Formation,and the Jehol Biota (including Sinosauropterxy,Confuciusorns sanctus,Archaefructus,etc.) is yielded in the second member of Yixian Formation. From west to east,the volcanic activity of Yixian Formation changed regularly from early to late,and from basic and intermediate-basic to acid (alkali).

Application of multidisciplinary team-based integrated traditional Chinese medicine and Western medicine in rotator cuff injury patients undergoing arthroscopic surgery

BACKGROUND Arthroscopic rotator cuff repair is a common surgical treatment for rotator cuff injuries(RCIs).Although this procedure has certain clinical advantages,it requires rehabilitation management interventions to ensure therapeutic efficacy.AIM To investigate the effect of integrated traditional Chinese medicine and Western medicine(TCM-WM)under the multidisciplinary team(MDT)model on the postoperative recovery of patients undergoing arthroscopic surgery for RCIs.METHODS This study enrolled 100 patients who underwent arthroscopic rotator cuff repair for RCIs at the Seventh People’s Hospital of Shanghai University of Traditional Chinese Medicine between June 2021 and May 2024.They were divided into a control group(n=48)that received routine rehabilitation treatment and an experimental group(n=52)that received TCM-WM under the MDT model(e.g.,acupuncture,TCM traumatology and orthopedics,and rehabilitation).The results of the Constant–Murley Shoulder Score(CMS),Visual Analogue Scale(VAS),Shoulder Pain and Disability Index(SPADI),muscular strength evaluation,and shoulder range of motion(ROM)assessments were analyzed.RESULTS After treatment,the experimental group showed significantly higher CMS scores in terms of pain,functional activity,shoulder joint mobility,and muscular strength than the baseline and those of the control group.The experimental group also exhibited significantly lower VAS and SPADI scores than the baseline and those of the control group.In addition,the experimental group showed significantly enhanced muscular strength(forward flexor and external and internal rotator muscles)and shoulder ROM(forward flexion,abduction,and lateral abduction)after treatment compared with the control group.CONCLUSION TCM-WM under the MDT model improved shoulder joint function,relieved postoperative pain,promoted postoperative functional recovery,and facilitated the recovery of muscular strength and shoulder ROM in patients with RCIs who underwent arthroscopic rotator cuff repair.

Modeling Daily Average Temperatures in a Coastal Site of Central Africa: An Analysis of Seasonal Divisions

The seasonality and day-to-day variation of near-surface temperature patterns can greatly control nearly all physical and biological processes though temperature predictions at such scales remain challenging. This paper implements a simple analytical approach in order to generate daily average temperatures which implicitly accounts for surface heating and drivers through a comprehensive representation of station-based temperature records on a universal standard calendar propagated by the earth’s dynamics features. The modeled and observed pattern of daily temperatures exhibits a close agreement with the level of strength agreement exceeding 0.56. The extreme high and low values of the observed temperature patterns are equally well captured although model underestimates the probability of temperatures around the two modal peaks (~25.6℃ and 27.5℃). Additionally, a theoretical thermal-based division led to the identification of six seasons, including two hot and cold periods along with two pairs of mixed hot-cold. The theoretical division proposed here appears to be a good approximation for the understanding of rainfall seasonality in this area.

Research on the Division of Small Layers of the Yan’an Group in the Western District of Mahuang Mountain

To supplement, adjust and improve the division plan of crude oil strata in the west of Mahuangshan Mountain. Combining well logging, core, and drilling analysis and testing data, Petrel software was utilized to classify and compare the 10 layers of the Yan’an Formation. Draw 6 “net-like” skeleton profiles for Ningdong No. 2 and No. 3 wells, involving 31 wells. On the basis of the large-layer strata division, Yan 8 and Yan 9 sections are divided and compared;five “net-like” skeleton profiles were drawn in the 5 well, involving 16 wells. On the basis of the large-layer division, the small-layer division and comparison were performed by Yan 8 and Yan 9. The results show that the Yan 8 oil layer is divided into two stratigraphic units, and Yan 8 and Yan 82, and the Yan 9 oil layer is divided into two stratigraphic units, Yan 91 and Yan 92;the Yan 2 layer in the 2 and 3 well blocks of Ningdong is in the marker layer. The top of the coal seam, Yan 8 layers in the Ningdong 5 well area is on the top of the auxiliary marker seam. The fine division of small layers into tiny layers of sedimentary microfacies, reservoir heterogeneity, development dynamic analysis, remaining oil distribution and other studies provide indispensable data.

Spatial Distribution and Potential Health Risk Assessment of Fluoride and Nitrate Concentrations in Groundwater from Mbour-Fatick Area, Western Central Senegal

This study aims to delineate the spatial distribution of nitrate and fluoride in groundwater and to estimate the non-carcinogenic risks using the human health risk assessment model recommended by the United States Environmental Protection Agency (USEPA). Forty-two samples were collected from wells and boreholes and analyzed for nitrate, fluoride and other water quality parameters. Results of the study indicate that fluoride and nitrate concentrations vary respectively from 0.13 to 9.41 mg·L−1 and from 0.13 to 432.24 mg·L−1 with respective median values of 2.65 and 13.85. About 69% of groundwater samples exceed the allowable limit (1.5 mg·L−1) of fluoride for drinking water. Spatial distribution of fluoride shows high concentrations in certain localities with values ranging from 6.74 mg·L−1 to 9.41 mg·L−1. The spatial distribution of nitrate indicates that the majority of water samples (87.18%) have nitrate concentrations lower than the World Health Organization (WHO) standard guideline value of 50 mg·L−1. Assessment of non-carcinogenic risks associated with intake of polluted groundwater in local populations indicates that 82.05% and 87.18% of groundwater samples have a THI > 1 in adults and children, respectively. However, the highest THI value (15.87) was recorded for children suggesting that children face greater non-carcinogenic risks than adults. The results of this study can be used as a support by the policymakers and practitioners to develop appropriate policies for effective and sustainable groundwater management and to monitor human health implications.

The Cumulative Method for Multiplication and Division

This paper provides a method of the process of computation called the cumulative method, it is based upon repeated cumulative process. The cumulative method is being adapted to the purposes of computation, particularly multiplication and division. The operations of multiplication and division are represented by algebraic formulas. An advantage of the method is that the cumulative process can be performed on decimal numbers. The present paper aims to establish a basic and useful formula valid for the two fundamental arithmetic operations of multiplication and division. The new cumulative method proved to be more flexible and made it possible to extend the multiplication and division based on repeated addition/subtraction to decimal numbers.

Machine learning solution for regional landslide susceptibility based on fault zone division strategy

Landslide susceptibility assessment is an essential tool for disaster prevention and management. In areas with multiple fault zones, the impact of fault zone on slope stability cannot be disregarded. This study performed qualitative analysis of fault zones and proposed a zoning method to assess the landslide susceptibility in Chengkou County, Chongqing Municipality, China. The region within a distance of 1 km from the faults was designated as sub-zone A, while the remaining area was labeled as sub-zone B. To accomplish the assessment, a dataset comprising 388 historical landslides and 388 non-landslide points was used to train the random forest model. 10-fold cross-validation was utilized to select the training and testing datasets for the model. The results of the models were analyzed and discussed, with a focus on model performance and prediction uncertainty. By implementing the proposed division strategy based on fault zone, the accuracy, precision, recall, F-score, and AUC of both two sub-zones surpassed those of the whole region. In comparison to the results obtained for the whole region, sub-zone B exhibited an increase in AUC by 6.15%, while sub-zone A demonstrated a corresponding increase of 1.66%. Moreover, the results of 100 random realizations indicated that the division strategy has little effect on the prediction uncertainty. This study introduces a novel approach to enhance the prediction accuracy of the landslide susceptibility mapping model in areas with multiple fault zones.