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Triangle分层护理管理对高血压患者血压水平和依从性的影响
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作者 卓素联 卢舒舒 《心血管病防治知识(学术版)》 2024年第1期81-83,共3页
目的 分析Triangle分层护理管理对高血压患者的影响。方法 抽取2019年6月至2022年12月共78例高血压住院患者作为研究对象,应用随机抽样法划分为两组,对照组中提供常规护理管理(n=39),研究组提供Triangle分层护理管理(n=39),对比分析两... 目的 分析Triangle分层护理管理对高血压患者的影响。方法 抽取2019年6月至2022年12月共78例高血压住院患者作为研究对象,应用随机抽样法划分为两组,对照组中提供常规护理管理(n=39),研究组提供Triangle分层护理管理(n=39),对比分析两组患者血压、依从率、自我管理行为、并发症。结果 患者管理前收缩压和舒张压显示无差异(P>0.05),管理后研究组低于照组,差异具有统计学意义(P<0.05);自我管理行为评分对比,管理前比较两组无差异(P>0.05),管理后升高,经对比,研究组评分高于另一组,差异具有统计学意义(P<0.05);依从率对比差异具有统计学意义(P<0.05),对照组(79.49%)低于研究组(94.87%);并发症发生率经对比差异具有统计学意义(P<0.05),研究组(2.56%)更低。结论 Triangle分层护理管理对高血压患者具有重要影响,能积极有效地控制血压,提高其治疗依从性、自我管理行为,并能降低并发症。 展开更多
关键词 高血压 依从性 常规护理管理 triangle分层护理管理 并发症
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以Triangle模型为基础的分级护理应用于糖尿病足患者的效果
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作者 李文芳 辛婧 +2 位作者 侯新凤 沈亚非 邓飞 《河南医学研究》 CAS 2024年第15期2869-2872,共4页
目的观察并分析以Triangle模型为基础的分级护理应用于糖尿病足患者的效果。方法选取漯河市中心医院2021年12月至2023年12月收治的97例糖尿病足患者,按照抽签法分组,常规组48例接受常规护理,研究组49例患者接受以Triangle模型为基础的... 目的观察并分析以Triangle模型为基础的分级护理应用于糖尿病足患者的效果。方法选取漯河市中心医院2021年12月至2023年12月收治的97例糖尿病足患者,按照抽签法分组,常规组48例接受常规护理,研究组49例患者接受以Triangle模型为基础的分级护理,均干预3个月后,比较两组溃疡修复情况、神经传导速度、自我效能、并发症及生活质量。结果研究组感觉检查、症状以及反射评分低于常规组(P<0.05)。研究组胫神经、腓总神经传导速度快于常规组(P<0.05)。研究组3个月后自我减压、自我决策、正性态度及生活质量评分均高于常规组(P<0.05)。研究组10 g尼龙绳触觉、痛觉、冷热觉及振动觉异常和下肢麻木发生率低于常规组(P<0.05)。两组皮肤干燥情况差异无统计学意义(P>0.05)。结论以Triangle模型为基础的分级护理可明显提高糖尿病足患者自我效能,有利于其溃疡修复和神经传导速度改善,减少并发症发生并促进生活质量的提高。 展开更多
关键词 糖尿病足 triangle模型 分级护理 神经传导速度 自我效能
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老年维持性腹膜透析病人Triangle分层分级管理体系的构建
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作者 黄翠婷 林舒丽 +2 位作者 韦春丽 施小燕 尹海鹰 《全科护理》 2024年第18期3378-3382,共5页
目的:构建适合老年维持性腹膜透析病人的分层分级管理体系,为老年腹膜透析病人的管理提供参考依据。方法:以Triangle分层分级管理模式为理论依据进行文献检索,通过半结构式访谈对15名从事腹膜透析及肾脏病临床管理的医护专家进行咨询,... 目的:构建适合老年维持性腹膜透析病人的分层分级管理体系,为老年腹膜透析病人的管理提供参考依据。方法:以Triangle分层分级管理模式为理论依据进行文献检索,通过半结构式访谈对15名从事腹膜透析及肾脏病临床管理的医护专家进行咨询,构建老年腹膜透析病人分层分级管理内容框架。结果:2轮问卷回收率均达到100%,2轮专家权威系数分别为0.870和0.923,肯德尔协调系数分别为0.318和0.433,第2轮专家函询中各指标重要性赋分均数为4.07~4.93,变异系数为0.05~0.15。最终构建包括6个1级指标,45个2级指标的老年维持性腹膜透析病人Triangle分层分级管理体系。结论:该研究构建的老年维持性腹膜透析病人Triangle分层分级管理体系内容具有科学性和可靠性,可为老年维持性腹膜透析病人的管理提供依据,具有理论和实际意义。 展开更多
关键词 老年 维持性腹膜透析 triangle分层分级 专家咨询法
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糖尿病肾病开展Triangle分层分级管理+LEARNS模式的效果及心理状态的观察 被引量:1
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作者 周静 李麟玲 +1 位作者 汪海红 杨玉琼 《昆明医科大学学报》 CAS 2024年第4期197-202,共6页
目的探究在对糖尿病肾病患者护理时开展Triangle分层分级管理+LEARNS模式对患者血糖水平、肾功能水平以及心理状态等改善作用。方法在2022年2月至2023年1月云南省第三人民医院收治糖尿病肾病患者中随机抽选74例为对象,Excel表随机排序... 目的探究在对糖尿病肾病患者护理时开展Triangle分层分级管理+LEARNS模式对患者血糖水平、肾功能水平以及心理状态等改善作用。方法在2022年2月至2023年1月云南省第三人民医院收治糖尿病肾病患者中随机抽选74例为对象,Excel表随机排序划分对照组(n=37,治疗期间接受常规护理)和观察组(n=37,接受Triangle分层分级管理+LEARNS模式护理)。针对患者血压水平、肾功能水平等改善情况进行评估。结果对比2组干预前后血糖水平,餐后2 h血糖、空腹血糖,干预后观察组低于对照组,差异有统计学意义(P<0.05)。对比患者生存质量,干预前无差异,干预后观察组QOLIE-31量表评分高于对照组,差异有统计学意义(P<0.05)。对比患者负面情绪评分,干预前BAI以及BDI评分无差异,干预后观察组评分低于对照组,差异有统计学意义(P<0.05)。对比患者肾功能水平,干预后观察组肾功能水平高于对照组,差异有统计学意义(P<0.05)。对比2组自我管理能力,干预后观察组高于对照组,差异有统计学意义(P<0.05)。结论在对糖尿病肾病患者护理时开展Triangle分层分级管理+LEARNS模式,可改善患者血糖、肾功能水平,缓解患者治疗期间负面情绪,有助于患者进行恢复。 展开更多
关键词 糖尿病肾病 triangle分层分级管理 LEARNS模式 心理状态
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基于Triangle模型的分层分级延续性护理在2型糖尿病病人中的应用研究 被引量:1
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作者 唐莉莉 詹宪玲 +3 位作者 刘倩倩 李娜 陈环环 蔡敏 《全科护理》 2024年第4期702-706,共5页
目的:分析基于Triangle模型的分层分级延续护理在2型糖尿病(T2DM)病人中的应用效果。方法:纳入2021年11月—2022年11月在徐州医科大学附属宿迁医院接受治疗的120例T2DM病人,按随机数字表法分为观察组与对照组,各60例。对照组接受延续性... 目的:分析基于Triangle模型的分层分级延续护理在2型糖尿病(T2DM)病人中的应用效果。方法:纳入2021年11月—2022年11月在徐州医科大学附属宿迁医院接受治疗的120例T2DM病人,按随机数字表法分为观察组与对照组,各60例。对照组接受延续性护理,观察组接受基于Triangle模型的分层分级延续性护理。于干预前、干预3个月时、干预6个月时评定病人血糖控制状况、自我管理能力、生活质量;并记录病人干预期间再住院次数。结果:干预3个月、6个月时,两组病人空腹血糖(FPG)、餐后2 h血糖(2 h PG)、糖化血红蛋白(HbA1c)水平明显低于干预前,糖尿病自我管理行为量表(SDSCA)得分高于干预前,中国糖尿病病人生存质量特异性量表(DSQL)得分低于干预前,且观察组病人各项指标改善优于对照组(P<0.05);但两组病人干预6个月时的各项指标与干预3个月时比较,差异无统计学意义(P>0.05);观察组病人再住院次数少于对照组(P<0.05)。结论:基于Triangle模型的分层分级延续性护理可提高T2DM病人的血糖控制水平、自我管理能力及生活质量,并减少再住院次数。 展开更多
关键词 2型糖尿病 triangle分层分级模型 延续性护理
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Hydrocarbon accumulation in deep ancient carbonate-evaporite assemblages 被引量:1
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作者 SHI Shuyuan HU Suyun +10 位作者 LIU Wei WANG Tongshan ZHOU Gang XU Anna HUANG Qingyu XU Zhaohui HAO Bin WANG Kun JIANG Hua MA Kui BAI Zhuangzhuang 《Petroleum Exploration and Development》 SCIE 2024年第1期54-68,共15页
The Ediacaran–Ordovician strata within three major marine basins(Tarim,Sichuan,and Ordos)in China are analyzed.Based on previous studies focusing on the characteristics of the Neoproterozoic–Cambrian strata within t... The Ediacaran–Ordovician strata within three major marine basins(Tarim,Sichuan,and Ordos)in China are analyzed.Based on previous studies focusing on the characteristics of the Neoproterozoic–Cambrian strata within the three major basins(East Siberian,Oman,and Officer in Australia)overseas,the carbonate–evaporite assemblages in the target interval are divided into three types:intercalated carbonate and gypsum salt,interbedded carbonate and gypsum salt,and coexisted carbonate,gypsum salt and clastic rock.Moreover,the concept and definition of the carbonate-evaporite assemblage are clarified.The results indicate that the oil and gas in the carbonate-evaporite assemblage are originated from two types of source rocks:shale and argillaceous carbonate,and confirmed the capability of gypsum salt in the saline environment to drive the source rock hydrocarbon generation.The dolomite reservoirs are classified in two types:gypseous dolomite flat,and grain shoal&microbial mound.This study clarifies that the penecontemporaneous or epigenic leaching of atmospheric fresh water mainly controlled the large-scale development of reservoirs.Afterwards,burial dissolution transformed and reworked the reservoirs.The hydrocarbon accumulation in carbonate-evaporite assemblage can be categorized into eight sub-models under three models(sub-evaporite hydrocarbon accumulation,supra-evaporite hydrocarbon accumulation,and inter-evaporite hydrocarbon accumulation).As a result,the Cambrian strata in the Tazhong Uplift North Slope,Maigaiti Slope and Mazatag Front Uplift Zone of the Tarim Basin,the Cambrian strata in the eastern-southern area of the Sichuan Basin,and the inter-evaporite Ma-4 Member of Ordovician in the Ordos Basin,China,are defined as favorable targets for future exploration. 展开更多
关键词 carbonate-evaporite assemblage dolomite reservoir source rock hydrocarbon accumulation Sichuan Basin Tarim Basin Ordos Basin
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Hydrocarbon accumulation and orderly distribution of whole petroleum system in marine carbonate rocks of Sichuan Basin,SW China 被引量:1
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作者 GUO Xusheng HUANG Renchun +3 位作者 ZHANG Dianwei LI Shuangjian SHEN Baojian LIU Tianjia 《Petroleum Exploration and Development》 SCIE 2024年第4期852-869,共18页
Based on the situation and progress of marine oil/gas exploration in the Sichuan Basin,SW China,the whole petroleum system is divided for marine carbonate rocks of the basin according to the combinations of hydrocarbo... Based on the situation and progress of marine oil/gas exploration in the Sichuan Basin,SW China,the whole petroleum system is divided for marine carbonate rocks of the basin according to the combinations of hydrocarbon accumulation elements,especially the source rock.The hydrocarbon accumulation characteristics of each whole petroleum system are analyzed,the patterns of integrated conventional and unconventional hydrocarbon accumulation are summarized,and the favorable exploration targets are proposed.Under the control of multiple extensional-convergent tectonic cycles,the marine carbonate rocks of the Sichuan Basin contain three sets of regional source rocks and three sets of regional cap rocks,and can be divided into the Cambrian,Silurian and Permian whole petroleum systems.These whole petroleum systems present mainly independent hydrocarbon accumulation,containing natural gas of affinity individually.Locally,large fault zones run through multiple whole petroleum systems,forming a fault-controlled complex whole petroleum system.The hydrocarbon accumulation sequence of continental shelf facies shale gas accumulation,marginal platform facies-controlled gas reservoirs,and intra-platform fault-and facies-controlled gas reservoirs is common in the whole petroleum system,with a stereoscopic accumulation and orderly distribution pattern.High-quality source rock is fundamental to the formation of large gas fields,and natural gas in a whole petroleum system is generally enriched near and within the source rocks.The development and maintenance of large-scale reservoirs are essential for natural gas enrichment,multiple sources,oil and gas transformation,and dynamic adjustment are the characteristics of marine petroleum accumulation,and good preservation conditions are critical to natural gas accumulation.Large-scale marginal-platform reef-bank facies zones,deep shale gas,and large-scale lithological complexes related to source-connected faults are future marine hydrocarbon exploration targets in the Sichuan Basin. 展开更多
关键词 Sichuan Basin margin oil/gas whole petroleum system carbonate hydrocarbon accumulation hydrocarbon distribution law hydrocarbon exploration target
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Triangle分层分级管理模型在下肢静脉溃疡患者护理中的研究进展
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作者 顾飞 王娴 《当代护士(下旬刊)》 2024年第8期25-29,共5页
对下肢静脉溃疡疾病的现状、国内外Triangle分层分级管理模型的应用现状进行综述,对下肢静脉溃疡患者分层分级管理的相关管理方式、评价指标及随访方式进行归纳总结,旨在为下肢静脉溃疡患者提供更具有层次化、条理化的管理,为临床护理... 对下肢静脉溃疡疾病的现状、国内外Triangle分层分级管理模型的应用现状进行综述,对下肢静脉溃疡患者分层分级管理的相关管理方式、评价指标及随访方式进行归纳总结,旨在为下肢静脉溃疡患者提供更具有层次化、条理化的管理,为临床护理人员管理下肢静脉溃疡患者提供参考依据。 展开更多
关键词 triangle分层分级管理 下肢静脉溃疡 护理
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基于Triangle分层分级管理的LEARNS健康教育在高血压患者中的应用
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作者 高丽萍 潘玲芳 《心血管病防治知识(学术版)》 2024年第8期101-105,共5页
目的探讨基于Triangle分层分级管理的LEARNS健康教育对高血压患者的影响。方法选取2023年1-10月在本院就诊的高血压患者176例,采用数字表法将其随机分为对照组(88例,给予常规健康教育)和观察组(88例,开展基于Triangle分层分级管理的LEA... 目的探讨基于Triangle分层分级管理的LEARNS健康教育对高血压患者的影响。方法选取2023年1-10月在本院就诊的高血压患者176例,采用数字表法将其随机分为对照组(88例,给予常规健康教育)和观察组(88例,开展基于Triangle分层分级管理的LEARNS健康教育),比较两组干预前及干预3个月后高血压知识知晓率、自我管理行为以及血压水平。结果对照组有1例中途失访,观察组1例失访、1例主动要求退出,予以脱落,最终对照组87例、观察组86例。观察组干预后成人的血压正常值、高血压患病危险因素及合并症和防治原则等相关知识知晓率均高于对照组(P<0.05),自我管理行为量表(HPSMBRS)中的饮食、用药、情绪及病情监测评分分别为(40.11±5.09)分、(16.88±3.40)分、(26.77±4.10)分及(16.99±3.10)分,均高于对照组(33.45±5.10)分、(13.55±2.31)分、(23.45±4.23)分及(13.44±2.17)分(P<0.05),收缩压(SBP)为(130.11±5.34)mmHg、舒张压(DBP)为(85.76±9.23)mmHg均低于对照组(143.22±5.01)mmHg和(90.12±6.11)mmHg(P<0.05)。结论基于Triangle分层分级管理的LEARNS健康教育在高血压患者中应用效果显著,可提高患者疾病知识知晓度和自我管理行为水平,有效改善血压水平。 展开更多
关键词 高血压 健康教育 triangle分层分级管理 LEARNS模式 血压
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TRIANGLE operation,combined with adequate adjuvant chemotherapy,can improve the prognosis of pancreatic head cancer:A retrospective study
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作者 Jia-Hao Chen Li-Yong Zhu +7 位作者 Zhi-Wei Cai Xiao Hu Abousalam Abdoulkader Ahmed Jie-Qiong Ge Xiao-Yan Tang Chun-Jing Li Yun-Long Pu Chong-Yi Jiang 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第5期1773-1786,共14页
BACKGROUND The TRIANGLE operation involves the removal of all tissues within the triangle bounded by the portal vein-superior mesenteric vein,celiac axis-common hepatic artery,and superior mesenteric artery to improve... BACKGROUND The TRIANGLE operation involves the removal of all tissues within the triangle bounded by the portal vein-superior mesenteric vein,celiac axis-common hepatic artery,and superior mesenteric artery to improve patient prognosis.Although previously promising in patients with locally advanced pancreatic ductal adenocarcinoma(PDAC),data are limited regarding the long-term oncological outcomes of the TRIANGLE operation among resectable PDAC patients undergoing pancreaticoduodenectomy(PD).AIM To evaluate the safety of the TRIANGLE operation during PD and the prognosis in patients with resectable PDAC.METHODS This retrospective cohort study included patients who underwent PD for pancreatic head cancer between January 2017 and April 2023,with or without the TRIANGLE operation.Patients were divided into the PD_(TRIANGLE)and PD_(non-TRIANGLE)groups.Surgical and survival outcomes were compared between the two groups.Adequate adjuvant chemotherapy was defined as adjuvant chemotherapy≥6 months.RESULTS The PD_(TRIANGLE)and PD_(non-TRIANGLE) groups included 52 and 55 patients,respectively.There were no significant differences in the baseline characteristics or perioperative indexes between the two groups.Furthermore,the recurrence rate was lower in the PD_(TRIANGLE) group than in the PD_(non-TRIANGLE) group(48.1%vs 81.8%,P<0.001),and the local recurrence rate of PDAC decreased from 37.8%to 16.0%.Multivariate Cox regression analysis revealed that PD_(TRIANGLE)(HR=0.424;95%CI:0.256-0.702;P=0.001),adequate adjuvant chemotherapy≥6 months(HR=0.370;95%CI:0.222-0.618;P<0.001)and margin status(HR=2.255;95%CI:1.252-4.064;P=0.007)were found to be independent factors for the recurrence rate.CONCLUSION The TRIANGLE operation is safe for PDAC patients undergoing PD.Moreover,it reduces the local recurrence rate of PDAC and may improve survival in patients who receive adequate adjuvant chemotherapy. 展开更多
关键词 triangle operation Pancreatic ductal adenocarcinoma Heidelberg triangle Adjuvant chemotherapy PROGNOSIS PANCREATICODUODENECTOMY
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Quantitative prediction model for the depth limit of oil accumulation in the deep carbonate rocks:A case study of Lower Ordovician in Tazhong area of Tarim Basin
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作者 Wen-Yang Wang Xiong-Qi Pang +3 位作者 Ya-Ping Wang Zhang-Xin Chen Fu-Jie Jiang Ying Chen 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期115-124,共10页
With continuous hydrocarbon exploration extending to deeper basins,the deepest industrial oil accumulation was discovered below 8,200 m,revealing a new exploration field.Hence,the extent to which oil exploration can b... With continuous hydrocarbon exploration extending to deeper basins,the deepest industrial oil accumulation was discovered below 8,200 m,revealing a new exploration field.Hence,the extent to which oil exploration can be extended,and the prediction of the depth limit of oil accumulation(DLOA),are issues that have attracted significant attention in petroleum geology.Since it is difficult to characterize the evolution of the physical properties of the marine carbonate reservoir with burial depth,and the deepest drilling still cannot reach the DLOA.Hence,the DLOA cannot be predicted by directly establishing the relationship between the ratio of drilling to the dry layer and the depth.In this study,by establishing the relationships between the porosity and the depth and dry layer ratio of the carbonate reservoir,the relationships between the depth and dry layer ratio were obtained collectively.The depth corresponding to a dry layer ratio of 100%is the DLOA.Based on this,a quantitative prediction model for the DLOA was finally built.The results indicate that the porosity of the carbonate reservoir,Lower Ordovician in Tazhong area of Tarim Basin,tends to decrease with burial depth,and manifests as an overall low porosity reservoir in deep layer.The critical porosity of the DLOA was 1.8%,which is the critical geological condition corresponding to a 100%dry layer ratio encountered in the reservoir.The depth of the DLOA was 9,000 m.This study provides a new method for DLOA prediction that is beneficial for a deeper understanding of oil accumulation,and is of great importance for scientific guidance on deep oil drilling. 展开更多
关键词 Deep layer Tarim Basin Hydrocarbon accumulation Depth limit of oil accumulation Prediction model
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Effect of non-uniform swelling on coal multiphysics during gas injection: The triangle approach
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作者 Yifan Huang Jishan Liu +2 位作者 Yaoyao Zhao Derek Elsworth Yee-Kwong Leong 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第4期1362-1372,共11页
In current dual porosity/permeability models,there exists a fundamental assumption that the adsorption-induced swelling is distributed uniformly within the representative elementary volume (REV),irrespective of its in... In current dual porosity/permeability models,there exists a fundamental assumption that the adsorption-induced swelling is distributed uniformly within the representative elementary volume (REV),irrespective of its internal structures and transient processes.However,both internal structures and transient processes can lead to the non-uniform swelling.In this study,we hypothesize that the non-uniform swelling is responsible for why coal permeability in experimental measurements is not only controlled by the effective stress but also is affected by the adsorption-induced swelling.We propose a concept of the swelling triangle composed of swelling paths to characterize the evolution of the non-uniform swelling and serve as a core link in coupled multiphysics.A swelling path is determined by a dimensionless volumetric ratio and a dimensionless swelling ratio.Different swelling paths have the same start and end point,and each swelling path represents a unique swelling case.The swelling path as the diagonal of the triangle represents the case of the uniform swelling while that as the two perpendicular boundaries represents the case of the localized swelling.The paths of all intermediate cases populate inside the triangle.The corresponding relations between the swelling path and the response of coal multiphysics are established by a non-uniform swelling coefficient.We define this method as the triangle approach and corresponding models as swelling path-based ones.The proposed concept and models are verified against a long-term experimental measurement of permeability and strains under constant effective stress.Our results demonstrate that during gas injection,coal multiphysics responses have a close dependence on the swelling path,and that in both future experiments and field predictions,this dependence must be considered. 展开更多
关键词 Transient process HETEROGENEITY Swelling triangle Swelling path Non-uniform swelling coefficient
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基于Triangle分层分级管理的LEARNS模式对妊娠期糖尿病孕期血糖控制水平及母婴结局
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作者 刘伟 《中华养生保健》 2024年第8期109-112,共4页
目的探讨基于Triangle分层分级管理的LEARNS模式对妊娠期糖尿病孕期血糖控制水平及母婴结局影响。方法选取山东省滕州市妇幼保健院2021年1月—2022年12月收治的116例妊娠期糖尿病孕妇,应用抽签法将孕妇分为观察组与对照组,每组58例。对... 目的探讨基于Triangle分层分级管理的LEARNS模式对妊娠期糖尿病孕期血糖控制水平及母婴结局影响。方法选取山东省滕州市妇幼保健院2021年1月—2022年12月收治的116例妊娠期糖尿病孕妇,应用抽签法将孕妇分为观察组与对照组,每组58例。对照组实施常规护理,观察组实施基于Triangle分层分级管理的LEARNS模式干预。分别在干预前后应用一般自我效能量表(GSES)对两组孕妇的自我效能进行评价,应用健康促进生活方式量表Ⅱ(HPLPⅡ)评价两组孕妇生活健康水平,并对比两组产妇干预前后血糖水平及母婴结局。结果干预后,两组GSES、HPLPⅡ评分均升高,观察组GSES、HPLPⅡ评分高于对照组,差异有统计学意义(P<0.05);干预后,两组空腹血糖、餐后2 h血糖、糖化血红蛋白水平均降低,观察组空腹血糖、餐后2 h血糖、糖化血红蛋白水平低于对照组,差异有统计学意义(P<0.05);观察组妊娠不良结局、围产儿不良结局发生率明显低于对照组,差异有统计学意义(P<0.05)。结论基于Triangle分层分级管理的LEARNS模式可提升妊娠期糖尿病孕妇自我效能及健康生活水平,更有利于产妇孕期血糖控制,进而降低母婴不良结局发生率。 展开更多
关键词 triangle分层分级管理 LEARNS模式 妊娠期糖尿病 血糖水平 母婴结局
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Barley Protein LFBEP-C1 from Lactiplantibacillus plantarum dy-1 Fermented Barley Extracts by Inhibiting Lipid Accumulation in a Caenorhabditis elegans Model
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作者 ZHANG Jia Yan LIU Meng Ting +4 位作者 LIU Yu Hao DENG Huan BAI Juan XIE Jian Hua XIAO Xiang 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第4期377-386,共10页
Objective This study aimed to investigate the lipid-lowering activity of LFBEP-C1 in high glucose-fed Caenorhabditis elegans(C.elegans).Methods In this study,the fermented barley protein LFBEP-C1 was prepared and test... Objective This study aimed to investigate the lipid-lowering activity of LFBEP-C1 in high glucose-fed Caenorhabditis elegans(C.elegans).Methods In this study,the fermented barley protein LFBEP-C1 was prepared and tested for its potential anti-obesity effects on C.elegans.The worms were fed Escherichia coli OP50(E.coli OP50),glucose,and different concentrations of LFBEP-C1.Body size,lifespan,movement,triglyceride content,and gene expression were analyzed.The results were analyzed using ANOVA and Tukey's multiple comparison test.Results Compared with the model group,the head-swing frequency of C.elegans in the group of LFBEP-C1 at 20μg/mL increased by 33.88%,and the body-bending frequency increased by 27.09%.This indicated that LFBEP-C1 improved the locomotive ability of C.elegans.The average lifespan of C.elegans reached 13.55 days,and the body length and width of the C.elegans decreased after LFBEP-C1 intake.Additionally,LFBEP-C1 reduced the content of lipid accumulation and triglyceride levels.The expression levels of sbp-1,daf-2,and mdt-15 significantly decreased,while those of daf-16,tph-1,mod-1,and ser-4 significantly increased after LFBEP-C1 intake.Changes in these genes explain the signaling pathways that regulate lipid metabolism.Conclusion LFBEP-C1 significantly reduced lipid deposition in C.elegans fed a high-glucose diet and alleviated the adverse effects of a high-glucose diet on the development,lifespan,and exercise behavior of C.elegans.In addition,LFBEP-C1 regulated lipid metabolism mainly by mediating the expression of genes in the sterol regulatory element-binding protein,insulin,and 5-hydroxytryptamine signaling pathways. 展开更多
关键词 LFBEP-C1 Fermentation Protein Caenorhabditis elegans Lipid accumulation Signaling pathway
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Lysine 2-hydroxyisobutyrylation levels determined adipogenesis and fat accumulation in adipose tissue in pigs
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作者 Enfa Yan Mingyang Tan +4 位作者 Ning Jiao Linjuan He Boyang Wan Xin Zhang Jingdong Yin 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第5期2093-2105,共13页
Background Excessive backfat deposition lowering carcass grade is a major concern in the pig industry,especially in most breeds of obese type pigs.The mechanisms involved in adipogenesis and fat accumulation in pigs r... Background Excessive backfat deposition lowering carcass grade is a major concern in the pig industry,especially in most breeds of obese type pigs.The mechanisms involved in adipogenesis and fat accumulation in pigs remain unclear.Lysine 2-hydroxyisobutyrylation(Khib),is a novel protein post-translational modification(PTM),which play an important role in transcription,energy metabolism and metastasis of cancer cells,but its role in adipogenesis and fat accumulation has not been shown.Results In this study,we first analyzed the modification levels of acetylation(Kac),Khib,crotonylation(Kcr)and succinylation(Ksu)of fibro-adipogenic progenitors(FAPs),myogenic precursors(Myo)and mesenchymal stem cells(MSCs)with varied differentiation potential,and found that only Khib modification in FAPs was significantly higher than that in MSCs.Consistently,in parallel with its regulatory enzymes lysine acetyltransferase 5(KAT5)and histone deacetylase 2(HDAC2)protein levels,the Khib levels increased quadratically(P<0.01)during adipogenic differentiation of FAPs.KAT5 knockdown in FAPs inhibited adipogenic differentiation,while HDAC2 knockdown enhanced adipogenic differentiation.We also demonstrated that Khib modification favored to adipogenic differentiation and fat accumulation by comparing Khib levels in FAPs and backfat tissues both derived from obese-type pigs(Laiwu pigs)and lean-type pigs(Duroc pigs),respectively.Accordingly,the expression patterns of KAT5 and HDAC2 matched well to the degree of backfat accumulation in obese-and lean-type pigs.Conclusions From the perspective of protein translational modification,we are the first to reveal the role of Khib in adipogenesis and fat deposition in pigs,and provided new clues for the improvement of fat accumulation and distribution as expected via genetic selection and nutritional strategy in obese-type pigs. 展开更多
关键词 ADIPOGENESIS BACKFAT Fat accumulation 2-Hydroxyisobutyrylation Intramuscular fat content PIGS
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Comparison of prognosis and postoperative morbidities between standard pancreaticoduodenectomy and the TRIANGLE technique for resectable pancreatic ductal adenocarcinoma
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作者 He-Xing Hang Zheng-Hua Cai +3 位作者 Yi-Fei Yang Xu Fu Yu-Dong Qiu Hao Cheng 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第3期689-699,共11页
BACKGROUND Radical surgery combined with systemic chemotherapy offers the possibility of long-term survival or even cure for patients with pancreatic ductal adenocar-cinoma(PDAC),although tumor recurrence,especially l... BACKGROUND Radical surgery combined with systemic chemotherapy offers the possibility of long-term survival or even cure for patients with pancreatic ductal adenocar-cinoma(PDAC),although tumor recurrence,especially locally,still inhibits the treatment efficacy.The TRIANGLE technique was introduced as an extended dissection procedure to improve the R0 resection rate of borderline resectable or locally advanced PDAC.However,there was a lack of studies concerning postoperative complications and long-term outcomes of this procedure on patients with resectable PDAC.PDAC.METHODS Patients with resectable PDAC eligible for PD from our hospital between June 2018 and December 2021 were enrolled in this retrospective cohort study.All the patients were divided into PDstandard and PDTRIANGLE groups according to the surgical procedure.Baseline characteristics,surgical data,and postoperative morbidities were recorded.All of the patients were followed up,and the date and location of tumor recurrence,and death were recorded.The Kaplan-Meier method and log-rank test were used for the survival analysis.RESULTS There were 93 patients included in the study and 37 underwent the TRIANGLE technique.Duration of operation was longer in the PDTRIANGLE group compared with the PDstandard group[440(410-480)min vs 320(265-427)min](P=0.001).Intraoperative blood loss[700(500-1200)mL vs 500(300-800)mL](P=0.009)and blood transfusion[975(0-1250)mL vs 400(0-800)mL](P=0.009)were higher in the PDTRIANGLE group.There was a higher incidence of surgical site infection(43.2%vs 12.5%)(P=0.001)and postoperative diarrhea(54.1%vs 12.5%)(P=0.001)in the PDTRIANGLE group.The rates of R0 resection and local recurrence,overall survival,and disease-free survival did not differ significantly between the two groups.CONCLUSION The TRIANGLE technique is safe,with acceptable postoperative morbidities compared with standardized PD,but it does not improve prognosis for patients with resectable PDAC. 展开更多
关键词 Pancreatic ductal adenocarcinoma triangle technique PANCREATICODUODENECTOMY PROGNOSIS Postoperative morbidities
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Triangle分层分级管理模式在慢性病病人健康促进行为中的应用进展
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作者 张晓玉 李莉莉 王亚琼 《循证护理》 2024年第19期3494-3498,共5页
将Triangle分层分级管理模式在国内外慢性病病人健康促进行为中的应用现状和经验进行综述,并提出展望,为改善慢性病病人健康促进行为提供参考依据。
关键词 triangle分层分级模型 慢性病 健康促进行为 生活质量 综述
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Regulation of different light conditions for efficient biomass production and protein accumulation of Spirulina platensis
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作者 Yufei ZHANG Xianjun LI +9 位作者 Yuhui LI Shiqi LIU Yanrui CHEN Miao JIA Xin WANG Lu ZHANG Qiping GAO Liang ZHANG Daoyong YU Baosheng GE 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2024年第1期174-186,共13页
Light plays an important role in the photosynthesis and metabolic process of microalgae.However,how different light conditions regulate the biomass production and protein accumulation of microalgae is mostly unknown.I... Light plays an important role in the photosynthesis and metabolic process of microalgae.However,how different light conditions regulate the biomass production and protein accumulation of microalgae is mostly unknown.In this study,the influence of different light conditions,including light colors,densities,and light:dark cycles on the cell growth and biochemical composition of Spirulina platensis was symmetrically characterized.Under different colored lights,S.platensis all shows an increase trend within the increased light intensity ranges;however,each showing different optimal light intensities.At the same light intensity,different colored lights show different growth rate of S.platensis following the sequence of red>white>green>yellow>blue.The maximum growth rate and protein accumulation were determined as 21.88 and 5.10 mg/(L·d)when illuminated under red LED.The energy efficiency of different light sources was calculated and ranked as red>white>blue≈green>yellow.Transcriptomic analysis suggests that red light can promote cell growth and protein accumulation by upregulating genes related to photosynthesis,carbon fixation,and C-N metabolism pathways.This study provides a conducive and efficient way to promote biomass production and protein accumulation of S.platensis by regulating light conditions. 展开更多
关键词 MICROALGAE light emitting diode protein accumulation biomass production transcriptomic analysis
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Accumulation of Heavy Metals in Maga-Pouss Rice Fields (Far-North Region, Cameroon) and Transfer to Rice Grains
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作者 Diane Madomguia Gilbert Bello Basokdou +3 位作者 Kalieu W. Appoline Isabelle Patrice Kuitekam Dongo Edouard Nya Serge Hubert Zebaze Togouet 《Agricultural Sciences》 2024年第3期311-326,共16页
Monitoring of heavy metals contamination of agricultural products and their transfer and bioaccumulation in crops like rice has become a hot topic worldwide over the last two decades. The present study was carried out... Monitoring of heavy metals contamination of agricultural products and their transfer and bioaccumulation in crops like rice has become a hot topic worldwide over the last two decades. The present study was carried out to determine the accumulation of heavy metals in rice fields and their transfer to rice grains. Soil, irrigation water and rice grains samples were gathered in Maga-Pouss, Far-North, Cameroon. Concentrations of six heavy metals (lead, cadmium, zinc, copper, iron and mercury) were evaluated by Atomic Absorption Spectrophotometer (AAS). Mercury was not detected in this study. Average concentrations of metals were in this order (in mg/kg): Fe (188.60 ± 97.06) > Pb (63.63 ± 7.11) > Cd (2.59 ± 0.29) > Zn (1.10 ± 1.05) > Cu (0.80 ± 0.73) in water and Pb (105.50 ± 31.11) > Fe (105.50 ± 31.11) > Cu (45.93 ± 14.39) > Zn (22.52 ± 6.40) > Cd (3.15 ± 0.49) in soil. Water in Maga-Pouss rice fields appears to be more harmful than the soil, notably for lead, cadmium and copper. In rice grains, heavy metals were found in this order (mg/kg): Fe (188.01 ± 82.62) > Cu (27.20 ± 0.00) > Zn (23.61 ± 12.42) > Pb (19.50 ± 19.91) > Cd (2.02 ± 1.05). The mean bioconcentration factor (BCF) of metals from soil to rice grains was in the following order: Fe (2.60) > Zn (1.05) > Cd (0.64) > Cu (0.59) > Pb (0.18). From water to rice grains, the order is: Cu (37.26) > Zn (22.49) > Cd (6.97) > Pb (2.74) > Fe (1.94). Rice field pH and electrical conductivity favored the uptake of lead, copper and cadmium by rice grains. The findings of this study will be good documentation for risk assessment, and decision-making by environmental managers in this region. 展开更多
关键词 Heavy Metals Rice Field Bioconcenration Factor Maga-Pouss accumulation
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Triangle分层分级管理结合LEARNS模式在糖尿病中的应用
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作者 余琦琦 张生娟 高菊 《糖尿病新世界》 2024年第9期131-134,共4页
目的研究糖尿病患者采用Triangle分层分级管理结合LEARNS模式干预的护理效果。方法选择2020年10月—2023年10月东南大学附属中大医院收治的40例糖尿病患者为研究对象,以随机抽签法分为A组(20例,行Triangle分层分级管理结合LEARNS模式护... 目的研究糖尿病患者采用Triangle分层分级管理结合LEARNS模式干预的护理效果。方法选择2020年10月—2023年10月东南大学附属中大医院收治的40例糖尿病患者为研究对象,以随机抽签法分为A组(20例,行Triangle分层分级管理结合LEARNS模式护理)和B组(20例,施行常规护理干预)。对比两组护理前后血糖水平、糖尿病自我管理行为量表(Summary of Diabetes Self Care Activities,SDSCA)评分及依从性。结果干预后,A组患者血糖水平显著优于B组,差异有统计学意义(P<0.05)。干预前,两组患者SDSCA评分对比,差异无统计学意义(P>0.05);干预后,A组SDSCA评分显著优于B组,差异有统计学意义(P<0.05)。A组患者依从性显著优于B组,差异有统计学意义(P<0.05)。结论给予糖尿病患者Triangle分层分级管理结合LEARNS模式进行干预,与常规护理干预对比,其能够很大程度改善患者血糖情况,提高糖尿病患者自我管理能力及依从性。 展开更多
关键词 triangle分层分级管理 LEARNS模式 糖尿病护理
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