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Rupture of an Infrarenal Aortic Aneurysm Due to a Secondary Type 1a Endoleak Following Endovascular Aneurysm Sealing with the Nellix<sup>&reg;</sup>Device
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作者 Kudla Dorothea Uhl Christian +2 位作者 Zorger Niels Steinbauer Markus Topel Ingolf 《Surgical Science》 2019年第11期398-404,共7页
Purpose: The Nellix endovascular aneurysm sealing (EVAS) system was introduced in 2010 for infrarenal abdominal aortic aneurysm (AAA) repair. So far one secondary type 1a endoleak resulting in rupture of the aneurysm ... Purpose: The Nellix endovascular aneurysm sealing (EVAS) system was introduced in 2010 for infrarenal abdominal aortic aneurysm (AAA) repair. So far one secondary type 1a endoleak resulting in rupture of the aneurysm has been reported. Case report: We present a case of a rupture of an infrarenal aortic aneurysm due to a secondary type 1a endoleak caused by stent migration 14 months after endovascular aneurysm sealing with a Nellix system. Conclusion: Strict adherence to anatomical requirements given by the instructions for use during patient selection and thorough post interventional surveillance may reduce the probability of secondary type 1a endoleaks. Furthermore, device design changes, especially concerning the configuration of the proximal part of the stent graft, have to be considered. 展开更多
关键词 ENDOVASCULAR ANEURySM SEALING SECONDARy type 1a ENDOLEAK rupture Abdominal Aortic ANEURySM
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Successful coil embolization with a basic technique for ruptured posterior tibial artery in a patient with Ehlers-Danlos syndrome type IV: A case report
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作者 Satoko Nezu Morio Nagahata +2 位作者 Keisuke Onishi Rei Kondo Shinjiro Saito 《Case Reports in Clinical Medicine》 2013年第2期131-134,共4页
The surgical management of vascular complication with Ehlers-Danlos Syndrome type IV (EDS-IV) is extremely challenging because of its tissue or organ fragility including arteries. Less traumatic maneuvers and devices ... The surgical management of vascular complication with Ehlers-Danlos Syndrome type IV (EDS-IV) is extremely challenging because of its tissue or organ fragility including arteries. Less traumatic maneuvers and devices have been recommended to perform the endovascular treatment for the vascular lesion of EDS-IV, although the endovascular procedure is less invasive than surgical intervention. We report a 23-year-old man with EDS-IV suffered from left posterior tibial arterial rupture. We performed internal trapping of the ruptured segment using detachable coils with a standard technique via the contralateral femoral artery puncture. The patient was discharged without any complication associated with the endovascular procedure. Embolization by a basic technique, performed with greatest care, is a safe and useful treatment option which we radiologists should try for managing EDS-IV patients. 展开更多
关键词 EHLERS-DANLOS Syndrome type IV PERIPHERAL ARTERIAL rupture Coil EMBOLIZATION
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Newly-generated Seismic Rupture Zone:Identification,Type Division and Seismogeological Significance
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作者 Xiang Hongfa, Zhang Wanxia, Guo Shunmin and Xu XiweiInstitute of Geology, China Seismological Bureau, Beijing 100029, China 《Earthquake Research in China》 2000年第1期66-78,共13页
The results of geological research show that those phenomena such as surface geology,geomorphology,deep geophysical field,and time-space distribution of seismicities can be usedas the main seismogeological indicators ... The results of geological research show that those phenomena such as surface geology,geomorphology,deep geophysical field,and time-space distribution of seismicities can be usedas the main seismogeological indicators to identify the newly-generated seismic rupture zone(NSRZ).According to their formation and evolution process,the NSRZs can be divided intothree types:pre-rupture-isolated,quasi-rupture-discontinuous and major-rupture-connected.In a pre-rupture-isolated NSRZ,the seismicity is dominated by medium-small earthquakes.In a quasi-rupture-discontinuous NSRZ,the frequency and intensity of strong earthquakesincrease and there may even be the largest earthquake to occur.A major-rupture-connectedNSRZ is the segment where rupture has entered the mature stage;in such a zone,theintensity and duration of seismic activity depend on the constitutive condition and regionalstress field in the zone. 展开更多
关键词 Newly-generated SEISMIC rupture zone (NSRZ) Identification type DIVISION Seismogeological SIGNIFICANCE
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Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)Y-type六角铁氧体的制备及磁性能
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作者 高熠斌 王松伟 +3 位作者 张鑫 杨瑞鑫 张亚乐 崔梦范 《桂林电子科技大学学报》 2024年第3期299-303,共5页
针对Y型六角铁氧体Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)单相多晶样品的固相法制备工艺及磁性能进行研究。通过粉末X射线衍射表征Y型六角铁氧体Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)单相多晶样品的物相及晶体结构,实验结果表明,当烧结... 针对Y型六角铁氧体Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)单相多晶样品的固相法制备工艺及磁性能进行研究。通过粉末X射线衍射表征Y型六角铁氧体Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)单相多晶样品的物相及晶体结构,实验结果表明,当烧结温度为1120~1160℃,有M相产生,随着温度升高,M相的衍射峰逐渐减小;当烧结温度达到约1170℃时,得到Y型六角铁氧体Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)的单相。通过扫描电子显微镜及能谱研究样品的微观结构、形貌及成分,统计结果表明,Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)铁氧体呈现拉长的六角形形貌,平均晶粒尺寸约3μm,同时还存在小的颗粒,且2种形貌的成分相同。利用综合物性测量系统对样品的磁特性进行表征,发现在330 K和90 K温度附近存在2种磁性异常,分析表明,330 K附近的磁性异常对应锥形磁结构相变,90 K附近的磁性异常对应自旋玻璃相变。Y型六角铁氧体Ba_(0.4)Sr_(1.6)Mg_(2)Fe_(12)O_(22)锥形磁相变的磁有序温度高于室温,为室温下磁电耦合提供可能。 展开更多
关键词 y型六角铁氧体 固相法 磁性能 磁相变
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一种Y型延迟荧光分子及其蓝光和绿光OLED应用 被引量:2
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作者 孙静 樊志杰 +2 位作者 杜纪宽 董海亮 王华 《发光学报》 EI CAS CSCD 北大核心 2024年第1期78-85,共8页
以噻吨酮作为受体、3,6-(二咔唑基)三咔唑作为给体设计合成了一种具有延迟荧光特性的Y型分子(TX-TCz)。模拟计算表明化合物HOMO和LUMO能级完全分离且在苯环上存在较小的重叠,有助于获得小的S1和T1的能级差ΔEST。随着溶剂极性的增加,化... 以噻吨酮作为受体、3,6-(二咔唑基)三咔唑作为给体设计合成了一种具有延迟荧光特性的Y型分子(TX-TCz)。模拟计算表明化合物HOMO和LUMO能级完全分离且在苯环上存在较小的重叠,有助于获得小的S1和T1的能级差ΔEST。随着溶剂极性的增加,化合物发射峰发生明显的红移且由于电荷转移态和局域激发态的共存产生了双峰发射。在纯膜中TX-TCz的发射峰位于513 nm,量子产率为11.5%。基于低温下荧光和磷光发射峰,计算得到化合物的ΔEST为0.03 eV,并且检测到µs级的寿命,说明化合物具有延迟荧光发射。与此同时,化合物展示了良好的热稳定性能和电化学性能,有助于制备高性能OLED器件。其在掺杂浓度为5%(wt)的器件中展示了良好的蓝光性能,发射峰位于463 nm,最大外量子效率为1.53%;在非掺杂器件中展示了良好的绿光发射(522 nm),最大外量子效率达到1.81%。 展开更多
关键词 OLED y型分子 蓝光/绿光 延迟荧光
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Preparation and Characterization of Y-type Carbon Nanotubes by Using Anodized Alumina Oxide (AAO) Template 被引量:2
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作者 张静 高泉涌 杨勇 《电化学》 CAS CSCD 2003年第4期381-386,共6页
 利用两步氧化法,通过对氧化直流电压进行周期性调制可制备出带有Y型孔道的氧化铝模板;然后以金属钴为催化剂,乙炔为碳源,通过CVD法制取得到具有规则Y型分支的碳纳米管阵列.已制备出的碳管分支角度在20°~120°的范围内.实验...  利用两步氧化法,通过对氧化直流电压进行周期性调制可制备出带有Y型孔道的氧化铝模板;然后以金属钴为催化剂,乙炔为碳源,通过CVD法制取得到具有规则Y型分支的碳纳米管阵列.已制备出的碳管分支角度在20°~120°的范围内.实验表明,两段分支所成的角度以及分支的长度与合成氧化铝模板的脉冲电压调节规律有关,短脉冲,高氧化电压有利于生长出的短而密集的分支构型. 展开更多
关键词 y型分支 碳纳米管 氧化铝模板法 制备 表征 脉冲电压 电化学
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腹腔镜Roux-en-Y胃旁路术治疗肥胖糖尿病20例疗效分析
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作者 艾克拜尔·艾力 崔剑昱 +7 位作者 皮尔地瓦斯·麦麦提玉素甫 麦麦提艾力·麦麦提明 伊比提哈尔·买买提艾力 李慧灵 邓秀丽 玉素江·图荪托合提 黎鑫 克力木·阿不都热依木 《临床外科杂志》 2024年第7期733-735,共3页
目的探讨腹腔镜Roux-en-Y胃旁路手术(LRYGB)治疗肥胖糖尿病的临床疗效。方法回顾性分析2012年~2018年新疆维吾尔自治区人民医院微创、疝腹壁外科中心实施LRYGB的20例肥胖糖尿病人的临床资料。结果20例手术均顺利完成,中转开腹病例1例。... 目的探讨腹腔镜Roux-en-Y胃旁路手术(LRYGB)治疗肥胖糖尿病的临床疗效。方法回顾性分析2012年~2018年新疆维吾尔自治区人民医院微创、疝腹壁外科中心实施LRYGB的20例肥胖糖尿病人的临床资料。结果20例手术均顺利完成,中转开腹病例1例。手术时间60~420分钟,平均(150±105.64)分钟,术中失血量20~100ml,平均(37.5±20.99)ml,术后住院时间5~15天,平均(8.25±2.51)天。术后5年内7例(35.00%)发生并发症,均为Clavien-Dindo分级Ⅱ级。术后1、3、5年的体重、体质指数(BMI)、糖化血红蛋白、空腹血糖、总体重减少百分比(TWL%)与术前比较均有改善,差异有统计学意义(P<0.05)。术后5年LRYGB治疗2型糖尿病完全缓解15例(75.00%)。结论LRYGB对肥胖2型糖尿病病人是一种有效的减重及降糖的术式。 展开更多
关键词 腹腔镜胃旁路手术 肥胖 2型糖尿病 减重手术 腹腔镜胃袖状切除术
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Ruptured hepatoblastoma with massive internal bleeding in an adult 被引量:3
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作者 Hung-Yen Ke Yee-Min Jen +2 位作者 Jyh-Cherng Yu Chung-Bao Hsieh Cheng-Jueng Chen 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第39期6235-6237,共3页
Hepatoblastoma is the most common primary hepatic tumor of children. However, only a very few cases have been reported in adults. Most studies support treatment with chemotherapy followed by surgical resection. We pre... Hepatoblastoma is the most common primary hepatic tumor of children. However, only a very few cases have been reported in adults. Most studies support treatment with chemotherapy followed by surgical resection. We present the first reported case of adult hepatoblastoma in Taiwan. A 52-year-old female suffered from sudden onset of abdominal pain and general weakness for days.Internal bleeding with hemorrhagic shock was suspected and two massive lesions in both lobes of the liver with hemoperitoneum were noted from imaging studies.Surgical resection of the larger left lobe tumor and radio-frequency ablation of the right smaller one were performed. The histopathology diagnosis was of a hepatoblastoma. 展开更多
关键词 Adult hepatoblastoma Hepatoblastoma rupture Internal bleeding HEPATOBLASTOMA Mixed type hepatoblastoma
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血清金属蛋白酶组织抑制剂3和性别决定区Y框蛋白2在2型糖尿病肾损伤早期诊断中的临床应用
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作者 张洪利 王海成 +2 位作者 李华 未瑞超 曾玲 《临床肾脏病杂志》 2024年第7期529-535,共7页
目的探究血清金属蛋白酶组织抑制剂3(tissue inhibitors of metalloproteinases 3,TIMP3)和性别决定区Y框蛋白2(transcription factor determining region Y box protein 2,SOX2)对2型糖尿病(type 2 diabetes mellitus,T2DM)肾损伤的早... 目的探究血清金属蛋白酶组织抑制剂3(tissue inhibitors of metalloproteinases 3,TIMP3)和性别决定区Y框蛋白2(transcription factor determining region Y box protein 2,SOX2)对2型糖尿病(type 2 diabetes mellitus,T2DM)肾损伤的早期诊断。方法选取2022年4月至2023年4月在华北石油管理局总医院就诊的102例T2DM患者为研究对象,根据24 h尿蛋白排泄率(uri-nary albumin excretion rate,UAER)将T2DM患者分为肾损伤组(n=40)和无肾损伤组(n=62),另选取同期在华北石油管理局总医院行体检的健康者50名为对照组。酶联免疫吸附法测定所有受试者血清TIMP3、SOX2水平;比较3组受试者一般资料、糖化血红蛋白(hemoglobin A1c,HbA1c)、UAER、血肌酐(serum creatinine,Scr)、估算肾小球滤过率(estimated glomerular filtration rate,eGFR)、血清TIMP3、SOX2水平;Pearson相关性分析血清TIMP3与SOX2及两者与HbA1c、UAER、Scr、eGFR之间的关系;受试者工作特征曲线(receiver operating characteristic curve,ROC)分析血清TIMP3、SOX2对T2DM患者肾损伤的诊断价值。结果T2DM患者血清TIMP3[(0.68±0.17)μg/L比(1.35±0.35)μg/L]及eGFR[(105.99±20.56)mL·min^(-1)·(1.73 m^(2))比(133.15±26.18)mL·min^(-1)·(1.73 m^(2))^(-1)]显著低于对照组(P<0.05),且肾损伤患者血清TIMP3[(0.47±0.11)μg/L比(0.82±0.21)^(-1)μg/L]及eGFR[(74.69±10.22)mL·min^(-1)·(1.73 m^(2))比(126.18±27.23)mL·min^(-1)·(1.73 m^(2))^(-1)]显著低于无肾损伤患者(P<0.05);血清SOX2[(8.91±1.82)kU/L比(5.15±1.31)kU/L]及HbA1c[(8.80±1.55)%比(5.52±0.83)%]、UAER[(70.13±18.06)mg/24 h比(13.22±3.61)mg/24 h]、Scr[(82.14±15.23)µmol/L比(53.19±5.62)µmol/L]显著高于对照组(P<0.05),且肾损伤患者血清SOX2[(10.81±2.13)kU/L比(5.15±1.31)kU/L]及UAER[(156.83±40.29)mg/24 h比(13.22±3.61)mg/24 h]、Scr[(113.77±13.58)µmol/L比(53.19±5.62)µmol/L]显著高于无肾损伤患者(P<0.05)。Pearson相关性分析结果显示,TIMP3与UAER、Scr、HbA1c呈显著负相关(P<0.05),与eGFR呈显著正相关(P<0.05);SOX2与UAER、Scr、HbA1c呈显著正相关(P<0.05),与eGFR呈显著负相关(P<0.05);血清TIMP3与SOX2呈显著负相关(r=-0.590,P<0.05)。ROC结果显示,血清TIMP3联合SOX2诊断T2DM患者肾损伤的敏感度和特异度分别为95.0%、85.3%,显著高于TIMP3、SOX2单独测定。结论T2DM肾损伤患者血清TIMP3水平显著降低,SOX2水平显著升高,且两者与T2DM患者肾损伤密切相关,可用于T2DM患者肾损伤早期诊断。 展开更多
关键词 金属蛋白酶组织抑制剂3 性别决定区框蛋白2 2型糖尿病 肾损伤 早期诊断
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Double-directional control bolt support technology and engineering application at large span Y-type intersections in deep coal mines 被引量:13
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作者 GUO, Zhibiao SHI, Jianjun +2 位作者 WANG, Jiong CAI, Feng WANG, Fuqiang 《Mining Science and Technology》 EI CAS 2010年第2期254-259,共6页
Under deep and complex geological conditions,severe deformation occurs at intersection points of Y-type roadways with large cross sections during engineering projects in coal mines,especially at junction arches.Based ... Under deep and complex geological conditions,severe deformation occurs at intersection points of Y-type roadways with large cross sections during engineering projects in coal mines,especially at junction arches.Based on in-situ investigations and theoretical studies,we have summarized typical forms of destruction and identified high stress and unrestricted support at both sides of junction arch as its main causes.In this study,we also presented double-directional control bolt support technology for a large Y-type span intersection,applied to deep intersection engineering in the Jiahe Coal Mine,which has proved effective. 展开更多
关键词 y-type intersection double-directional control bolt support deep coal mines
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Comparison of different gastric bypass procedures in gastric carcinoma patients with type 2 diabetes mellitus 被引量:3
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作者 Shao-Wei Xiong Dong-Yun Zhang +2 位作者 Xian-Ming Liu Zeng Liu Fang-Ting Zhang 《World Journal of Gastroenterology》 SCIE CAS 2014年第48期18427-18431,共5页
AIM: To determine the effect of different Roux-en-Y gastric bypass procedures in gastric carcinoma patients with type 2 diabetes mellitus.
关键词 Roux-en-y gastric bypass type 2 diabetes mellitus Gastric cancer Fasting plasma glucose Hemoglobin A1C
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Short-type single balloon enteroscope for endoscopic retrograde cholangiopancreatography with altered gastrointestinal anatomy 被引量:10
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作者 Hiroshi Yamauchi Mitsuhiro Kida +7 位作者 Kosuke Okuwaki Shiro Miyazawa Tomohisa Iwai Miyoko Takezawa Hidehiko Kikuchi Maya Watanabe Hiroshi Imaizumi Wasaburo Koizumi 《World Journal of Gastroenterology》 SCIE CAS 2013年第11期1728-1735,共8页
AIM:To evaluate the effectiveness of a short-type single-balloon-enteroscope(SBE) for endoscopic retrograde cholangiopancreatography(ERCP) in patients with a reconstructed intestine.METHODS:Short-type SBE was develope... AIM:To evaluate the effectiveness of a short-type single-balloon-enteroscope(SBE) for endoscopic retrograde cholangiopancreatography(ERCP) in patients with a reconstructed intestine.METHODS:Short-type SBE was developed to perform ERCP in postoperative patients with a reconstructed intestine.Short-type SBE is a direct-viewing endoscope with the following specifications:working length,1520 mm;total length,1840 mm;channel diameter,3.2 mm.In addition,short-type SBE has a water-jet channel.The study group comprised 22 patients who underwent 31 sessions of short-type SBE-assisted ERCP from June 2011 through May 2012.Reconstruction was performed by Billroth-Ⅱ(B-Ⅱ) gastrectomy in 6 patients(8 sessions),Roux-en-Y(R-Y) gastrectomy in 14 patients(21 sessions),and R-Y hepaticojejunostomy in 2 patients(2 sessions).We retrospectively studied the rate of reaching the blind end(papilla of Vater or choledochojejunal anastomosis),mean time required to reach the blind end,diagnostic success rate(defined as the rate of successfully imaging the bile and pancreatic ducts),therapeutic success rate(defined as the rate of successfully completing endoscopic treatment),mean procedure time,and complications.RESULTS:Among the 31 sessions of ERCP,the rate of reaching the blind end was 88% in B-Ⅱ gastrectomy,91% in R-Y gastrectomy,and 100% in R-Y hepaticojejunostomy.The mean time required to reach the papilla was 18.3 min in B-Ⅱ gastrectomy,21.1 min in R-Y gastrectomy,and 32.5 min in R-Y hepaticojejunostomy.The diagnostic success rates in all patients and those with an intact papilla were respectively 86% and 86% in B-Ⅱ gastrectomy,90% and 87% in R-Y gastrectomy,and 100% in R-Y hepaticojejunostomy.The therapeutic success rates in all patients and those with an intact papilla were respectively 100% and 100% in B-Ⅱ gastrectomy,94% and 92% in R-Y gastrectomy,and 100% in R-Y hepaticojejunostomy.Because the channel diameter was 3.2 mm,stone extraction could be performed with a wire-guided basket in 12 sessions,and wireguided intraductal ultrasonography could be performed in 8 sessions.As for complications,hyperamylasemia(defined as a rise in serum amylase levels to more than 3 times the upper limit of normal) occurred in 1 patient(7 sessions) with a B-Ⅱ gastrectomy and 4 patients(19 sessions) with an R-Y gastrectomy.After ERCP in patients with an R-Y gastrectomy,2 patients(19 sessions) had pancreatitis,1 patient(21 sessions) had gastrointestinal perforation,and 1 patient(19 sessions) had papillary bleeding.Pancreatitis and bleeding were both mild.Gastrointestinal perforation improved after conservative treatment.CONCLUSION:Short-type SBE is effective for ERCP in patients with a reconstructed intestine and allows most conventional ERCP devices to be used. 展开更多
关键词 Endoscopic RETROGRADE CHOLANGIOPANCREATOGRAPHy Single-balloon-enteroscope Short type BillrothII GASTRECTOMy ROUX-EN-y GASTRECTOMy
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Roux-en-Y gastric bypass for Chinese type 2 diabetes mellitus patients with a BMI,28kg/m^2:a multi-institutional study 被引量:13
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作者 Hui Liang Wei Guan +4 位作者 Yanling Yang Zhongqi Mao Yijun Mei Huan Liu Yi Miao 《The Journal of Biomedical Research》 CAS CSCD 2015年第2期112-117,共6页
Roux-en-Y gastric bypass surgery(RYGB) has been demonstrated to be successful for treating type-II diabetes2mellitus(T2DM) patients with a body mass index(BMI),30 kg/m,but reports of RYGB for T2 DM patients with... Roux-en-Y gastric bypass surgery(RYGB) has been demonstrated to be successful for treating type-II diabetes2mellitus(T2DM) patients with a body mass index(BMI),30 kg/m,but reports of RYGB for T2 DM patients with22 a BMI,28 kg/mare lacking.T2 DM patients with a BMI,28 kg/mwere prospectively recruited to participate in this study in four hospitals.The endpoint was T2 DM remission(defined by fasting blood glucose(FBG) level,110 mg/d L and hemoglobin(Hb)A1c level,6.0% at 12 months postoperatively).Predictors of remission were investigated by univariate and multivariate analyses.Eighty-six patients were assessed.Eighty-five patients underwent RYGB,with one conversion to open surgery.We compared the values of various variables before and after2 surgery.The mean BMI decreased from 24.68±2.12 to 21.72±2.43 kg/m(P,0.001).Fifty-eight(67.4%) patients were not treated by drugs or insulin after surgery,and 20 patients(23.3%) had complete remission of T2 DM at12 months after surgery with an acceptable number of complications.The mean Hb A1 c level in the remission group was significantly lower than that in the non-remission group.Patients with a higher weight,lower Hb A1 c level,higher C-peptide level,and higher FBG level were more likely to have T2 DM remission in multivariate2 analyses.In conclusion,RYGB was effective and safe for treating T2 DM patients with a BMI,28 kg/m.Complete remission can be predicted by cases having a higher weight,lower Hb A1 c level,higher C-peptide level,and higher FBG level. 展开更多
关键词 Roux-en-y gastric bypass type 2 diabetes mellitus Hb A1c C-PEPTIDE body mass index metabolic surgery
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Primary Ovarian Small Cell Carcinoma of Pulmonary Type: Analysis of 6 Cases and Review of 31 Cases in the Literatures 被引量:1
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作者 Xu Chen Hong-Ling Liu +1 位作者 Jin-Sui Wang Feng-Hui Zhao 《Chinese Medical Sciences Journal》 CAS CSCD 2023年第2期130-137,共8页
Objective Primary ovarian small cell carcinoma of pulmonary type(SCCOPT)is a rare ovarian tumor with a poor prognosis.The platinum-based chemotherapy is the standard treatment.However,there is little research on the c... Objective Primary ovarian small cell carcinoma of pulmonary type(SCCOPT)is a rare ovarian tumor with a poor prognosis.The platinum-based chemotherapy is the standard treatment.However,there is little research on the clinical characteristics of SCCOPT and the potential benefits of other treatments due to its low incidence.The study aims to investigate clinicopathological characteristics and treatment of SCCOPT.Methods We summarized the clinical,imaging,laboratorical and pathological characteristics of 37 SCCOPT cases,in which 6 cases were admitted to the Gansu Provincial Hospital from the year of 2008 to 2022 and 31 cases reported in 17 English and 3 Chinese literatures.Results The median age of the studied SCCOPT cases(n=37)was 56.00(range,22-80)years.Almost 80%of them had a stageⅢorⅣtumor.All patients underwent an operation and postoperative chemotherapy.Nevertheless,all cases had a poor prognosis,with a median overall survival time of 12 months.Immunohistochemical y,the SCCOPT of all patients showed positive expressions of epithelial markers,such as CD56 and sex-determining region of Y chromosome-related high-mobility-group box 2(SOX-2),and negative expressions of estrogen receptor,progesterone receptor,vimentin,Leu-7,and somatostatin receptor 2.The tumor of above 80%cases expressed synaptophysin.Only a few cases expressed neuron-specific enolase,chromogranin A,and thyroid transcription factor-1.Conclusions SCCOPT had a poor prognosis.SOX-2 could be a biomarker to be used to diagnose SCCOPT. 展开更多
关键词 small cell carcinoma of the ovary primary ovarian small cell carcinoma of pulmonary type sex-determining region of y chromosome-related high-mobility-group box 2 adjuvant chemotherapy
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Bariatric surgery as a treatment option in patients with type 2 diabetes mellitus 被引量:6
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作者 Marianna Spanou Konstantinos Tziomalos 《World Journal of Diabetes》 SCIE CAS 2013年第2期14-18,共5页
Type 2 diabetes mellitus (T2DM) is a leading cause of blindness, non-traumatic amputation and end-stage renal disease as well as a major cardiovascular risk factor. Tight glycemic control reduces the incidence of micr... Type 2 diabetes mellitus (T2DM) is a leading cause of blindness, non-traumatic amputation and end-stage renal disease as well as a major cardiovascular risk factor. Tight glycemic control reduces the incidence of microvascular complications of T2DM whereas its effects on macrovascular complication are more controversial. However, glycemic targets are achieved by a minority of diabetic patients despite the availability of several antidiabetic agents. In the present commentary, we discuss the findings of two recent randomized studies that compared bariatric surgery with medical treatment in patients with uncontrolled T2DM. Both studies showed that bariatric surgery results in remission of T2DM in the majority of patients. However, both studies were limited to relatively young patients without comorbidities, had relatively short follow-up and did not assess the effects of surgery on T2DM complications. Moreover, the perioperative complications of bariatric surgery and its limited availability in some areas are additional barriers to the wider implementation of this therapeutic approach. On the other hand, the elucidation of the mechanisms underpinning the resolution of T2DM following bariatric surgery might resultin the development of novel, more effective pharmacotherapies for this common disease. 展开更多
关键词 type 2 diabetes mellitu BARIATRIC surgery Roux-en-y GASTRIC bypass BILIOPANCREATIC DIVERSION Sleeve GASTRECTOMy Adjustable GASTRIC BANDING
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BASIN-RANGE TRANSITION AND GENETIC TYPES OF SEQUENCE BOUNDARY OF THE QIANGTANG BASIN IN NORTHERN TIBET
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作者 Yin Fuguang, Xu Xiaosong (Centre for Tethyan Geology,CAGS) 《地学前缘》 EI CAS CSCD 2000年第S1期141-142,共2页
The surface of sequence boundary is a negative record. Its recognition largely depends on the physics of the sediments below and above the boundaries, or on the different sedimentary structures are synthetic marks for... The surface of sequence boundary is a negative record. Its recognition largely depends on the physics of the sediments below and above the boundaries, or on the different sedimentary structures are synthetic marks for the sedimentation and tectonic movements in the sedimentary basin. The Qiangtang Basin that is in 5000m above the sea level is located in Northern Tibet. The Lazhulung—Jinshajiang suture zone now bound it to the north and the Bangong—Nujiang suture zone to the south. Three second\|order tectonic units have been distinguished, i.e. North Qiangtang depression, Central rise and South Qiangtang depression from north to south.The Upper Permian Riejuichaka Formation is built up of mudstone and mud\|limestone, which is represented by sediments in seamarsh. The Lower Triassic Kuanglu Formation, which exhibits the structure unconformable contact with the overlying Upper Permian strata, is characterized by terrigenous clastic rocks in the lower area and is carbonate rocks in the upwarding area and the Middle Triassic Kuangnan Formation. The Upper Triassic Xiachaka Formation consisting of terrigenous clastic rocks, carbonates rocks and mixed sediments, is confined to the uplift zones. The lower Jurassic volcanic rocks are deposited in continental rift. The middle and Upper Jurassic Yangshiping Group are conformable contact and assembled by the gypsum\|bearing terrigenous clastic rock formations and carbonate rock formation. The Middle Cretaceous and the Paleocene strata is built up of the terrigenous clastic rock formations. 展开更多
关键词 basin\|range TRANSITION genetic types sequence boundar y QIANGTANG BASIN NORTHERN TIBET
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Bariatric surgery-mediated weight loss and its metabolic consequences for type-2 diabetes 被引量:2
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作者 Rajendra Raghow 《World Journal of Diabetes》 SCIE CAS 2013年第3期47-50,共4页
The worldwide epidemic of obesity and its medical complications are being dealt with a combination of life style changes(e.g.,healthier diet and exercise),medications and a variety of surgical interventions.The Roux-e... The worldwide epidemic of obesity and its medical complications are being dealt with a combination of life style changes(e.g.,healthier diet and exercise),medications and a variety of surgical interventions.The Roux-en Y gastric bypass(RYGB) and laparoscopic adjustable gastric banding(LAGB) are two of the most common weight loss surgeries for morbid obesityassociated metabolic syndrome and insulin resistance.A vast majority of patients that undergo RYGB and LAGB are known to experience marked weight loss and attenuation of diabetes.A number of recent studies have indicated that the rates of remission in glycemic control and insulin sensitivity are significantly greater in patients that have undergone RYGB.A plausible hypothesis to explain this observation is that the gastric bypass surgery as opposed to the gastric banding procedure impinges on glucose homeostasis by a weight loss-independent mechanism.In a recent paper,Bradley et al have experimentally explored this hypothesis.The authors compared several clinical and laboratory parameters of insulin sensitivity and β-cell function in cohorts of RYGB and LAGB patients before and after they lost approximately 20% of their body mass.Afterweight loss,both groups of patients underwent similar changes in their intra-abdominal and total adipose tissue volume,hepatic triglyceride and circulating leptin levels.The RYGB patients who lost 20% body mass,manifested higher postprandial output of glucose,insulin and glucagon-like peptide-1;these laboratory parameters remained unchanged in LABG patients.Irrespective of the observed differences in transient responses of RYGB and LAGB patients to mixed meal,the overall glycemic control as judged by glucose tolerance,multi-organ insulin sensitivity and β-cell function were nearly identical in the two groups.Both RYGB and LAGB patient cohorts also experienced similar changes in the expression of a number of pro-and anti-inflammatory markers.Based on these analyses,Bradley et al concluded that similar restoration of insulin sensitivity and b-cell function in non-diabetic obese patients that have undergone RYGB and LAGB were directly due to marked weight loss.These data have important implications for the risk/benefit analysis of weight loss therapy by bariatric procedures. 展开更多
关键词 BARIATRIC surgery Roux-en y GASTRIC ByPASS Laparoscopic adjustable GASTRIC BANDING Weight loss type-2 DIABETES
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Interference of Y-27632 on the signal transduction of transforming growth factor beta type 1 in ocular Tenon capsule fibroblasts 被引量:7
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作者 Xiao-Hui Zhang, Jian-Ming Wang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2012年第5期576-581,共6页
AIM: To investigate the interfering effect of Y-27632, a ROCK-I selective inhibitor, on the signal transduction pathway of transforming growth factor-beta 1 (TGF-beta 1) in ocular Tenon capsule fibroblasts (OTFS) in v... AIM: To investigate the interfering effect of Y-27632, a ROCK-I selective inhibitor, on the signal transduction pathway of transforming growth factor-beta 1 (TGF-beta 1) in ocular Tenon capsule fibroblasts (OTFS) in vitro. METHODS: After OTFS from passages 4 to 6 47 vitro were induced by TGF-beta 1 and then treated by Y-27632, the changes of the OTFS cell cycles were analyzed via flow cytometry, and the proteins expression of the alpha -smooth muscular actin (alpha -SMA), connective tissue growth factor (CTGF), collagen I were calculated by Western blot. After OTFS treated by the different concentrations of Y-27632, the expression levels of the alpha -SMA, CTGF and collagen I mRNA were assayed by RT-PCR. RESULTS: Y-27632 had no markedly effect on the OTFS cell cycles. After treated by TGF-beta 1, OTFS in G1 period significantly increased. The cell cycles distribution by both TGF-beta 1 and Y-27632 had no remarkable difference from that in control group. Y-27632 significantly inhibited the proteins expressions of both alpha -SMA and CTGF, while to some extent inhibited that of collagen I. TGF-beta 1 significantly promoted the proteins expressions of alpha -SMA, CTGF and collagen I. After OTFS treated by both TGF-beta 1 and Y-27632, of alpha -SMA, the protein expression was similar with that in control group (P=0.066>0.05), but the protein expression of CTGF or collagen I, respectively, was significantly different from that in control group (P=0.000<0.01). The differences of expressions of the alpha -SMA, CTGF and collagen I mRNA in 30, 150, 750 mu mol/L Y-27632 group were statistically significant, compared with those in control group, respectively (alpha -SMA, P=0.002, 0.000, 0.000; CTGF, P=0.014, 0.002, 0.001; collagen I,P=0.003, 0.002, 0.000). CONCLUSION: Blocking the Rho/ROCK signaling pathway by using of Y-27632 could inhibit the cellular proliferation and the expression of both CTGF and alpha -SMA whatever OTFS induced by TGF-beta 1 or not. Y-27632 suppressed the expression of collagen I mRNA without induction. 展开更多
关键词 y-27632 ocular Tenon's capsule fibroblasts transforming growth factor beta type 1 α-smooth muscular actin connective tissue growth factor collagen I
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Surgical outcome of laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass for resolution of type 2 diabetes mellitus:A systematic review and meta-analysis 被引量:2
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作者 Salman Yousuf Guraya Tim Strate 《World Journal of Gastroenterology》 SCIE CAS 2020年第8期865-876,共12页
BACKGROUND Bariatric procedures are considered superior to medical therapies in managing type 2 diabetes mellitus(T2DM).Laparoscopic Roux-en-Y gastric bypass(LRYGB)and laparoscopic sleeve gastrectomy(LSG)are the most ... BACKGROUND Bariatric procedures are considered superior to medical therapies in managing type 2 diabetes mellitus(T2DM).Laparoscopic Roux-en-Y gastric bypass(LRYGB)and laparoscopic sleeve gastrectomy(LSG)are the most commonly used procedures for weight loss and comorbidity resolution worldwide.However,it is not yet known whether the degree of T2DM is influenced by the choice of bariatric procedure.AIM To quantitatively compare T2DM resolution over 1-5 years follow-up by LRYGB and LSG in morbidly obese patients.METHODS We searched the selected databases for full-text English language clinical studies that compared the effectiveness of LRYGB and LSG for T2DM resolution.Review manager 5.3 was used for data analysis,and the overall effect summary was represented in a forest plot.RESULTS From 1,650 titles retrieved by an initial search,we selected nine studies for this research.We found insignificant differences for T2DM resolution by LRYGB and LSG,with an odds ratio of 0.93(95%CI:0.64-1.35,Z statistics=0.38,P=0.71).Additionally,subset analyses for T2DM resolution showed insignificant differences after 24 mo(χ^2=1.24,df=4,P=0.87,overall Z effect=0.23),36 mo(χ^2=0.41,df=2,P=0.81,overall Z effect=0.51),and 60 mo(χ^2=4.75,df=3,P=0.19,overall Z effect=1.20)by LRYGB and LSG.This study reports a T2DM remission rate of 82.3%by LRYGB and 80.7%by LSG.CONCLUSION This study reports similar T2DM resolution rates by both LRYGB and LSG during 1-5 years of follow-up.However,long-term follow-up of 10 years is needed to further substantiate these findings. 展开更多
关键词 Morbid obesity type 2 diabetes mellitus Laparoscopic sleeve gastrectomy Laparoscopic Roux-en-y gastric bypass
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New Pyrometer with Double Y-type Optical Fibers
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作者 SHI Weidong, LI Zhiquan, TANG Xuhui, JIANG Wanlu(Yanshan University, Qinhuangdao 066004, CHN) 《Semiconductor Photonics and Technology》 CAS 1997年第1期40-43,49,共5页
Abstract: A new pyrometer, which can solve the affection of emissivity change in temperature measuring, has been developed by double Y - type optical fibers. The mathematical model of the new pyrometer is presented an... Abstract: A new pyrometer, which can solve the affection of emissivity change in temperature measuring, has been developed by double Y - type optical fibers. The mathematical model of the new pyrometer is presented and the errors of the new pyrometer are analyzed. 展开更多
关键词 EMISSIVITy Double y - type Optical Fibers PyROMETER
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