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余交换Hopf代数上Yang-Baxter方程的解
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作者 张雪倩 刘玲 吕家凤 《浙江师范大学学报(自然科学版)》 CAS 2024年第4期398-403,共6页
研究了Hopf brace的一些性质,并利用Rota-Baxter算子和Hopf brace探索了在余交换Hopf代数上Yang-Baxter方程的解,并给出了解在余交换Hopf代数k[G]上的具体形式.
关键词 余交换Hopf代数 Rota-Baxter算子 Hopf brace yang-BAXTER方程
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三维单左对称代数上的Nijenhuis算子和经典Yang-Baxter方程解
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作者 高翔 吕家凤 亢闯闯 《浙江师范大学学报(自然科学版)》 CAS 2024年第3期275-280,共6页
为了研究三维复单左对称代数上的Nijenhuis算子,通过求解结构常数构成的二次方程组,对三维复单左对称代数上的Nijenhuis算子进行了刻画.此外,利用所得结果,给出了半直积邻接李代数上的经典Yang-Baxter方程的解.
关键词 Nijenhuis算子 左对称代数 邻接李代数 经典yang-Baxter方程
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Beyond Gender Perspectives:A More Comprehensive Examination of Yang Yi’s Translation of Wuthering Heights
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作者 LIU Miao 《Sino-US English Teaching》 2024年第7期332-336,共5页
The renowned translator Yang Yi passed away in 2023.Many scholars argue that,influenced by their biological gender,female translators often employ translation methods in adherence to feminist translation or reflect ch... The renowned translator Yang Yi passed away in 2023.Many scholars argue that,influenced by their biological gender,female translators often employ translation methods in adherence to feminist translation or reflect characteristics typical of female translators.This study examines the translation of Wuthering Heights by Yang Yi,focusing on whether there is a definite influence of gender on translator behavior.While existing literature primarily analyzes Yang Yi’s work through a feminist lens,this research takes a broader approach.By considering the translator’s social background and translation practice,this paper challenges the assumption that her work strictly aligns with feminist translation theories.Instead,this study emphasizes the importance of considering diverse factors when interpreting translated works,moving beyond a singular gender-based standpoint. 展开更多
关键词 GENDER TRANSLATION yang Yi Wuthering Heights FEMINISM
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Twin Paradox and Proper Time
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作者 Donald Lem 《Journal of Applied Mathematics and Physics》 2024年第1期12-15,共4页
Professors Mohazzbi and Luo [1] published “Despite several attempts have been made to explain the twin paradox … none of the explanations … resolved the paradox. If the paradox can be ever resolved, it requires a m... Professors Mohazzbi and Luo [1] published “Despite several attempts have been made to explain the twin paradox … none of the explanations … resolved the paradox. If the paradox can be ever resolved, it requires a much deeper understanding … of the theory of relativity”. The deeper understanding of resolving the paradox is by applying more explicit definitions of proper time interval, Lorentz transform, time dilation, and aging time. 展开更多
关键词 Twin Paradox proper Time Minkowski Metric Schwarzschild Metric
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A study on the treatment of chloasma with moxibustion based on the theory of“Yang transforming Qi,and Yin shaping”
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作者 Mi Yang Hong-Yi Lan +2 位作者 Hong Wu Xu Wang Xin-Ju Li 《Clinical Research Communications》 2024年第3期23-28,共6页
Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of... Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of the strengths of TCM in treating diseases is holistic regulation.The theory of“Yang transforming Qi,and Yin shaping”implies a strong holistic view.Chloasma,one of the common skin diseases,seriously affects the physical and mental health of patients due to its unclear etiology,difficult treatment and easy recurrence.The occurrence and development of chloasma are closely related to internal organs.This paper is based on the theory of internal meridian,“Yang transforming Qi,and Yin shaping”which attaches importance to the concept of“Yang Qi”,from a new understanding of the pathogenesis etiology of chloasma.Methods:The author believes that the incidence of the disease is the deficiency of Yang Qi,which can’t promote the movement of Qi and blood to nourish the face,resulting in tangible material condensation,so proposes that this disease needs to be promoted by Yang transforming Qi and warm to dissipate.Moxibustion belongs to the fire,and its warming effect can dissipate the tangible evil.Results:Combined with clinical practice and the theory of internal meridian,the author elaborated that moxibustion is one of the effective methods for treating chloasma,which provides a new way of thinking for the treatment of chloasma.Conclusion:“Yang Transforming Qi and Yin shaping”can be used to guide the treatment of chloasma. 展开更多
关键词 yang Transforming Qi and Yin shaping MOXIBUSTION CHLOASMA
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Observation on the Nursing Effect of Ginger Moxibustion on Gastrointestinal Symptoms in Patients with Heart Failure Due to Yang Qi Deficiency
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作者 Yijing Wang 《Journal of Clinical and Nursing Research》 2024年第6期135-141,共7页
Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi defi... Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi deficiency type)accompanied by gastrointestinal symptoms who were admitted to the hospital between January 2023 and January 2024 were selected and divided into 43 cases in each group by random number table grouping;Group I implemented integrated care,while Group II adopted conventional care.The indicators of care were compared between the two groups.Results:After the nursing care,the digestive symptom scores of Group I were lower than those of Group I,and the psychological scores were lower than those of Group II(P<0.05).Conclusion:Ginger moxibustion can improve gastrointestinal symptoms and enhance the psychological health of patients with heart failure(yang qi deficiency type)with gastrointestinal symptoms. 展开更多
关键词 Ginger moxibustion yang qi deficiency Heart failure Gastrointestinal symptoms
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Clinical Nursing Intervention of Moxibustion on Abdominal Distension Symptoms in Heart Failure (Heart and Kidney Yang Deficiency and Blood Stasis Blocking Collaterals Syndrome)
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作者 Tingcui Yan 《Journal of Clinical and Nursing Research》 2024年第6期142-147,共6页
Objective:To investigate the clinical nursing intervention effect of moxibustion on abdominal distension symptoms in heart failure(heart and kidney yang deficiency and blood stasis blocking collaterals syndrome).Metho... Objective:To investigate the clinical nursing intervention effect of moxibustion on abdominal distension symptoms in heart failure(heart and kidney yang deficiency and blood stasis blocking collaterals syndrome).Methods:62 patients with heart failure(heart and kidney yang deficiency and blood stasis blocking collaterals syndrome)admitted to our hospital from February 2023 to February 2024 were selected and divided into the observation group(n=31)and the control group(n=31)by using the random numerical table method.The control group adopted conventional nursing interventions,and the observation group received the nursing program of the control group with the addition of moxibustion nursing interventions.The nursing effectiveness,quality of life scores,and nursing satisfaction were compared between the two groups.Results:The nursing effectiveness of the observation group was significantly higher than the control group(P<0.05);the quality of life score of the observation group was significantly higher than the control group(P<0.05);the nursing satisfaction of the observation group was significantly higher than that of the control group(P<0.05).Conclusion:The use of moxibustion nursing intervention in patients with heart failure(heart and kidney yang deficiency and blood stasis blocking collaterals syndrome)can effectively relieve the symptoms of abdominal distension,improve patients'quality of life,and increase nursing satisfaction,which has promotion and application values. 展开更多
关键词 MOXIBUSTION Heart failure Heart and kidney yang deficiency and blood stasis blocking collaterals syndrome Abdominal distension Nursing intervention
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From Hai Yao, Yang Yao to Xi Yao: Sinification of Material Medical from the West 被引量:1
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作者 Patrick Chiu 《Chinese Medicine and Culture》 2023年第4期319-329,共11页
In ancient China, Daoist philosophers developed the concepts of qi(energy), Wu Xing(five elements), and yin(feminine, dark, negative) and yang(masculine, bright, positive) opposite forces between 200 and 600 BCE. Base... In ancient China, Daoist philosophers developed the concepts of qi(energy), Wu Xing(five elements), and yin(feminine, dark, negative) and yang(masculine, bright, positive) opposite forces between 200 and 600 BCE. Based on these philosophies, Zhen Jiu(acupuncture), Ben Cao(materia medica), and the practice of Qi Gong(energy optimization movements) evolved as the three interrelated therapeutic regimens of Chinese medicine(Note 1). Since the time of Zhang Qian, who discovered China's western regions in the 1st century BCE, Hai Yao(the exotic elements of materia medica from the maritime Silk Road countries), had been transmitted from the ancient land and maritime routes of the Silk Road to China in the past two millennia(Note 2). Since the late 17th century, the English East India Company, later called the British East India Company, introduced Yang Yao(opium) to the Manchu Qing Empire to balance a growing trade deficit for tea export from China to the British Empire. After the First Opium War ended in 1842, enterprising expatriate chemists and druggists in the treaty ports imported Xi Yao(modern medicines from the Western world) for sale to the merchant navy and the local market. From the second half of the 19th century onwards, both Hai Yao and Xi Yao have become a fully integrated part of modern China's armamentarium for the Chinese medicine and Western hospitals and retail pharmacy sectors. This paper articulates the journey of adoption of exotic elements of materia medica from the ancient land and sea routes of the Silk Road, including the western regions and the rest of the world in the past two millennia. Opium traders, ship surgeons, medical and pharmaceutical missionaries, enterprising traders, and policymakers together transformed Ben Cao into Xi Yao during the late Manchu Qing dynasty and the early Nationalist Era. 展开更多
关键词 Hai Yao Materia Medica Opium Cures Xi Yao yang Yao
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Differential Effects of Yin- and Yang-Chinese Tonifying Herbs on Innate and Adaptive Immunity
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作者 Hoi Yan Leung Kam Ming Ko 《Chinese Medicine》 2023年第2期68-78,共11页
The present study investigated the effect of treatment with methanolic extracts of Yin- and Yang-Chinese tonifying herbs on concanavalin A (Con A)/lipopolysaccharide (LPS)-stimulated splenocyte proliferation (adaptive... The present study investigated the effect of treatment with methanolic extracts of Yin- and Yang-Chinese tonifying herbs on concanavalin A (Con A)/lipopolysaccharide (LPS)-stimulated splenocyte proliferation (adaptive immunity) and natural killer (NK) cell activity (innate immunity) in an ex vivo mouse model. The results indicated that while treatment with most Yin herbal extracts potentiated the Con A/LPS-stimulated splenocyte proliferation, only Yang (but not Yin) herbal extracts stimulated NK cell activity. The differential effects of Yin- and Yang-Chinese tonifying herbs on innate and adaptive immunity are consistent with the Chinese medicine theory which depicts the Yin and Yang functional components of Zheng Qi (vital energy), with the Yang component being responsible for the first line of defense against invading microorganisms (i.e., innate immunity) and the Yin oner serving as a follow-up defensive response (adaptive immunity). 展开更多
关键词 YIN yang Innate Immunity Adaptive Immunity Natural Killer Cell Activity Splenocyte Proliferation
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Effects of Manganese on the Antioxidant System and Related Gene Expression Levels in the “Hong Yang” Kiwifruit Seedlings
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作者 Chongpei Zheng Liangliang Li +2 位作者 Zhencheng Han Weijie Li Xiaopeng Wen 《Phyton-International Journal of Experimental Botany》 SCIE 2023年第8期2399-2412,共14页
To explore how manganese affects the antioxidant system and the expression levels of related genes of“Hong yang”seedlings,the leaves of its tissue cultured seedlings were taken as test materials,and single factor tr... To explore how manganese affects the antioxidant system and the expression levels of related genes of“Hong yang”seedlings,the leaves of its tissue cultured seedlings were taken as test materials,and single factor treatment was performed by changing the manganese chloride(MnCl_(2)·4H_(2)O)solution concentration when spraying the leaves.The expression levels of Mn-SOD,POD64 and POD27 genes in leaves were quantitatively analyzed by real-time quantitative PCR(qRT-PCR)at different determination times.Meanwhile,the contents of malondial-dehyde(MDA),hydrogen peroxide(H_(2)O_(2)),the activities of antioxidant enzymes,including catalase(CAT),peroxidase(POD),and superoxide dismutase(SOD).The results showed that the SOD,CAT,POD,ascorbate peroxidase(APX),and reduced glutathione(GSH)activities in leaves were the highest at 12 h post-treatment with 50μM MnCl_(2)·4H_(2)O.Furthermore,the contents of MDA and H_(2)O_(2) in leaves also peaked when the concentration of H_(2)O_(2) is 50μM,which is the minimum value.Additionally at 50μM Mn^(2+),the Mn-SOD and POD27 expression was up-regulated as compared to the control,which promoted the expression of their respective enzyme activities.However,POD64 expression increased with the increasing Mn^(2+) concentration.Therefore,50μM is the optimal concentration of Mn when exogenously applied on“Hong yang”,which improve the antioxidant enzyme activity and regulate the plant’s physiological and biochemical functions. 展开更多
关键词 “Hong yang”seedlings MANGANESE antioxidant system related gene expression
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Research on Yang Xiong from a Calligraphic Perspective
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作者 Tang Lin 《Contemporary Social Sciences》 2023年第3期117-131,共15页
Yang Xiong,a cultural celebrity in ancient China,is a well-known figure in the history of Chinese literature with abundant research on his literary achievements.However,little research has been done on the presentatio... Yang Xiong,a cultural celebrity in ancient China,is a well-known figure in the history of Chinese literature with abundant research on his literary achievements.However,little research has been done on the presentation of his name,former residence,and prose poems in Chinese calligraphy from an iconographic perspective.This paper intends to explore how“Yang Xiong,”“Yang Ziyun,”“Ziyun Pavilion in Xishu Prefecture,”and“Yang Xiong’s prose poems”are presented in the Chinese calligraphy,especially in calligraphies by Wang Xizhi,Su Dongpo,Huang Tingjian,Mi Fu,and other famous calligraphers in the previous dynasties.Research shows that Yang Xiong influenced not only Chinese literature but also Chinese calligraphy to a certain extent. 展开更多
关键词 previous dynasties CALLIGRAPHY PRESENTATION yang Xiong
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Transcriptomic and metabolomic analysis of the effects of Zhenwu decoction on kidney yang deficiency pattern in chronic kidney disease
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作者 Pengfei Zheng Yunhua Liu +5 位作者 Xinjiang Zhang Tingting Jiao Yingjie Wu Mengmeng Zhang Xinxue Zhang Zongjiang Zhao 《Journal of Traditional Chinese Medical Sciences》 CAS 2023年第2期228-243,共16页
Objective:To explore the kidney yang deficiency pattern(KYDP)in a chronic kidney disease(CKD)rat model and the mechanisms underlying the effects of Zhenwu decoction(ZWD)by conducting tran-scriptomic and metabolomic an... Objective:To explore the kidney yang deficiency pattern(KYDP)in a chronic kidney disease(CKD)rat model and the mechanisms underlying the effects of Zhenwu decoction(ZWD)by conducting tran-scriptomic and metabolomic analyses.Methods:Adriamycin(ADR)combined with hydrocortisone(HC)was used to induce CKD with KYDP in rats.ADR was injected into the tail vein twice.HC was injected intramuscularly for 8 weeks.ZWD was administered by gavage for 8 weeks.The general condition was observed,24-h urine protein was detected,serum corticosterone,triiodothyronine,thyroxine,TSH,testosterone,cAMP,and cGMP levels were determined,and pathological analysis was conducted.Transcriptomic and metabolomic analyses were conducted to screen differentially expressed genes(DEGs),differentially expressed metabolites(DEMs),and differentially expressed pathways(DEPs).The core DEMs and DEGs were input to Metab-oanalyst 5.0 to identify the pathways affected by ZWD.Results:In the HC group,KYDP symptoms were observed.Compared with control group,the levels of 24-h urine protein,TSH,and cGMP significantly increased(all P<0.01),and corticosterone,triiodothyronine,thyroxine,and cAMP significantly decreased(all P<0.01)in the HC group.After ZWD intervention,the levels of above-mentioned indicators could be reversed to some extent.Pathological analysis in the HC group revealed kidney lesions.DEGs in the ZWD group were mainly associated with pathways such as nucleotide synthesis and endocrine pathways.In the ZWD group,differences in biosynthesis of unsat-urated fatty acids and butanoate metabolism were observed.The following pathways were significantly affected by ZWD:arachidonic acid metabolism,valine,leucine,and isoleucine biosynthesis,linoleic acid metabolism,and alpha-linolenic acid metabolism.Conclusion:ZWD can be used to treat KYDP in CKD through regulating arachidonic acid metabolism,valine,leucine,and isoleucine biosynthesis,linoleic acid metabolism,and alpha-linolenic acid metabolism. 展开更多
关键词 Chronic kidney disease Kidney yang deficiency pattern Zhenwu decoction TRANSCRIPTOMICS Metabolomics
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Proper orthogonal decomposition based seismic source wavefield reconstruction for finite element reverse time migration
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作者 Wen-Zhuo Tan Bang-Yu Wu +1 位作者 Rui Li Bo Li 《Petroleum Science》 SCIE EI CAS CSCD 2023年第1期199-211,共13页
The large storage requirement is a critical issue in cross-correlation imaging-condition based reverse time migration(RTM),because it requires the operation of the source and receiver wavefields at the same time.The b... The large storage requirement is a critical issue in cross-correlation imaging-condition based reverse time migration(RTM),because it requires the operation of the source and receiver wavefields at the same time.The boundary value method(BVM),based on the finite difference method(FDM),can be used to reconstruct the source wavefield in the reverse time propagation in the same way as the receiver wavefield,which can reduce the storage burden of the RTM data.Considering that the FDM cannot well handle models with discontinuous material properties and rough interfaces,we develop a source wavefield reconstruction strategy based on the finite element method(FEM),using proper orthogonal decomposition(POD)to enhance computational efficiency.In this method,we divide the whole time period into several segments,and construct the POD basis functions to get a reduced order model(ROM)for the source wavefield reconstruction in each segment.We show the corresponding quantitative analysis of the storage requirement of the POD-FEM.Numerical tests on the homogeneous model show the effectiveness of the proposed method,while the layered model and part of the Marmousi model tests indicate that the POD-FEM can keep an excellent balance between computational efficiency and memory usage compared with the full-stored method(FSM)and the BVM,and can be effectively applied in imaging. 展开更多
关键词 Reverse time migration Seismic wavefield reconstruction Finite element modeling proper orthogonal decomposition
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k次幂等矩阵下Yang-Baxter矩阵方程所有解
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作者 廖洁 李沅津 +1 位作者 卢甫龙 周端美 《赣南师范大学学报》 2023年第6期7-10,共4页
令A是一个k次幂等矩阵并考虑Yang-Baxter矩阵方程AXA=XAX.基于先前关于可对角化系数矩阵的Yang-Baxter矩阵方程解的结果,可以推导得到方程的所有解.
关键词 yang-Baxter矩阵方程 幂等矩阵 特征值
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Clinical efficacy of external treatment with Zi Cao Yang He Tang combined with hormone therapy for granulomatous mastitis and its effect on cellular pyroptosis proteins
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作者 MU Yu-jing WANG Tang-shun +7 位作者 FENG Xue SUN Ping GAO Shuang WANG Yu-kun ZUO Xi-meng ZHU Yan-yan MA Yan SHI Xiao-guang 《Journal of Hainan Medical University》 CAS 2023年第22期23-23,共1页
Objective:To observe the clinical effect of external application of Zi Cao Yang He Tang combined with dexamethasone ointment in the treatment of granulomatous lobular mastitis in the mass stage and the effect on cellu... Objective:To observe the clinical effect of external application of Zi Cao Yang He Tang combined with dexamethasone ointment in the treatment of granulomatous lobular mastitis in the mass stage and the effect on cellular pyroptosis-related proteins.Methods:Forty patients with granulomatous lobular mastitis were randomly divided into 20 cases in the observation group and 20 cases in the control group.Both groups were given dexamethasone ointment for treatment,and the observation group was treated with external application of Zi Cao Yang He Tang on the basis of the control group.Breast lump vol-ume changes,breast pain and pus symptoms,pathology and histology and immunohistochemistry,cellular death-related indicators expression were compared between the two groups.Results:After treatment,the difference in mass volume of the observation group was significantly greater than that of the control group(16.7±21.5 in the control group and 32.9±27.4 in the experimental group)and the difference between the two groups was statistically significant(P<0.05);the objective remission rate of the patients in the observation group(ORR=85%)was significantly higher than that of the treatment group(ORR=50%,P<0.05).In terms of pus formation rate and pain level,the breast pain score of the observation group was significantly lower than that of the control group after two weeks or three weeks of treatment(P<0.05);the pus formation rate of the observation group was 30%,and the pus formation rate of the control group was 20%,and the difference was not statistically significant(P>0.05).The immunohistochemical expression levels of caspase-1 and GSDMD in the observation group were significantly lower than those in the control group(P<0.05);and in terms of the expression of cellular pyroptosis-related indexes,the expression of GSDMD,cas-pase-1,and NLRP3 in the observation group was significantly lower compared with that in the control group(P<0.05).Conclusion:The efficacy of external application of Zi Cao Yang He Tang combined with dexamethasone ointment in treating granulomatous lobular mastitis in the mass stage is remarkable,which can effectively reduce breast pain,reduce the size of the mass,de-crease the expression of cellular pyroptosisrelated indexes,and have a good anti-inflammatory effect. 展开更多
关键词 Zi Cao yang He Tang Granulomatous lobular mastitis Traditional Chinese medicine External treatment GLUCOCORTICOID
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A Comparative Study of YīJiàn Xiǎo Shìand A Small Incident Rendered by the Yangs
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作者 WANG Zai-jun ZHANG Jun-feng ZHANG Shun-sheng 《Journal of Literature and Art Studies》 2023年第11期825-830,共6页
Lu Xun’s short stories play a prominent role in the history of modern Chinese literature,and a number of Sinologists have studied them and published their English translations.This paper selects“YīJiàn Xiǎo S... Lu Xun’s short stories play a prominent role in the history of modern Chinese literature,and a number of Sinologists have studied them and published their English translations.This paper selects“YīJiàn Xiǎo Shì”in Lu Xun’s collection“Call to Arms”as the object of study,taking hypotaxis and parataxis as the starting point,and compares the translation of Yang Hsien-yi and Gladys Yang with the original version,studying the differences between the them in the process of C-E translation.It is hoped that some flexible conversion strategies in English-Chinese translation can be learned from the translation research. 展开更多
关键词 YīJiàn Xiǎo Shì A Small Incident rendered by yang Hsien-yi&Gladys yang hypotaxis and parataxis comparative study
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基于动响应数据特征的桥梁结构损伤识别 被引量:1
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作者 杨少冲 张凯 +1 位作者 李有晨 苏胜昔 《建筑结构》 北大核心 2024年第3期134-140,125,共8页
介绍了本征正交分解(Proper Orthogonal Decomposition,POD)的基本原理,探讨了POD在桥梁结构损伤识别中的应用。提出了基于动响应数据特征的桥梁结构损伤识别方法,该识别方法基于POD技术对桥梁结构在不同位置、不同时刻收集到的位移快... 介绍了本征正交分解(Proper Orthogonal Decomposition,POD)的基本原理,探讨了POD在桥梁结构损伤识别中的应用。提出了基于动响应数据特征的桥梁结构损伤识别方法,该识别方法基于POD技术对桥梁结构在不同位置、不同时刻收集到的位移快照矩阵(Snapshot Matrix)进行本征正交分解,得到结构的本征正交模态(POMs),进而构造出损伤指标来识别结构的损伤位置及程度,实现了对桥梁结构损伤的多工况识别。并以保定黄花沟桥为例,通过数值模拟试验,验证了该方法的有效性,结果表明POD能够从空心板桥结构的振动响应数据中提取出结构的本质特征,并且提取过程简单、快捷,可为桥梁结构提供一种有效的损伤识别方法。 展开更多
关键词 响应数据特征 本征正交分解 本征正交模态 损伤识别 健康监测
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The active mechanism of the Sheng Yang San Huo decoction on diabetic peripheral neuropathy on network pharmacology
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作者 Ying Wang Lei Hua +2 位作者 Guo Chen Zhen-Han Li Zhong-Pei Chen 《TMR Pharmacology Research》 2023年第3期16-24,共9页
Objectives:To discuss the mechanism of Sheng Yang San Huo decoction on diabetic peripheral neuropathy using the network pharmacology method.Methods:The BATMAN-TCM database,TCM-ID database,Chinese Natural Product Chemi... Objectives:To discuss the mechanism of Sheng Yang San Huo decoction on diabetic peripheral neuropathy using the network pharmacology method.Methods:The BATMAN-TCM database,TCM-ID database,Chinese Natural Product Chemical Composition Database,and TCMIP database were employed to screen the chemical active ingredients of each herb in Sheng Yang San Huo decoction based on the“Libinsky Drug Rules”.SwissTargetPrediction was used to screen effective action targets for each herb in the prescription.Additionally,Cytoscape 3.7.0 was utilized to construct a“drug-target”network.GeneCards,OMIM,and MaLaCards databases were utilized to gather targets related to diabetic peripheral neuropathy.VENNY 2.1 online platform was employed to match drug and disease targets,draw a Venn diagram,and construct a“drug-active compounds-common target”network using Cytoscape 3.7.0.gene ontology biological process analysis and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis for the targets were conducted using the DAVID 6.8 database.Enrichment analysis results were visualized using the OmicShareTool online platform.Molecular docking was performed using CB-Dock2.Results:Following screening,a total of 217 active compounds and 132 potential targets were identified in Sheng Yang San Huo decoction.The effects are primarily enriched in pathways such as Lipid and Atherosclerosis,AGE-RAGE signaling pathway in diabetic complications,and the IL-17 signaling pathway.The binding energy of the key active ingredients to the core protein targets of DPN was favorable.Conclusion:The study reveals the characteristics of multiple targets and pathways of Sheng Yang San Huo decoction,providing new insights for the clinical application of this prescription. 展开更多
关键词 Sheng yang San Huo Decoction Diabetic Peripheral Neuropathy Molecular Mechanism Network Pharmacology
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基于“阴阳自和”理论探讨自噬在老年血脂异常中的作用 被引量:1
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作者 金颖 隋国媛 +3 位作者 戴俭宇 王庆谚 李记泉 贾连群 《辽宁中医杂志》 CAS 北大核心 2024年第3期46-49,共4页
自噬是近年来的医学热点领域,在此过程中,受损细胞器、蛋白质聚集物和脂滴等通发生降解(阴),并在此过程中生成能量(阳)与机体衰老和能量代谢密切相关。自噬在维持细胞内稳态、应对细胞内应激中的作用与阴阳消长、阴阳互用实现动态平衡,... 自噬是近年来的医学热点领域,在此过程中,受损细胞器、蛋白质聚集物和脂滴等通发生降解(阴),并在此过程中生成能量(阳)与机体衰老和能量代谢密切相关。自噬在维持细胞内稳态、应对细胞内应激中的作用与阴阳消长、阴阳互用实现动态平衡,从而达到阴阳自和状态的过程不谋而合。中医理论分析认为老年血脂异常为本虚标实之证,与脾肾功能相关,与机体阴阳自和能力下降相关。文章尝试以中医阴阳理论为基础,探讨细胞自噬在老年血脂异常中的作用。 展开更多
关键词 阴阳自和 自噬 血脂异常 衰老
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某SUV气动减阻优化及其流场机制 被引量:2
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作者 邵景峰 左辉辉 胡兴军 《汽车工程》 EI CSCD 北大核心 2024年第2期356-365,共10页
为了提高整车燃油经济性,本文以某款SUV车型为研究对象,将仿真与试验相结合改善汽车行驶过程中的气动阻力系数。首先通过风洞试验确定对整车气动阻力有重要影响的区域或部件,其次对气动阻力系数贡献值较大的部件或区域进行减阻优化。结... 为了提高整车燃油经济性,本文以某款SUV车型为研究对象,将仿真与试验相结合改善汽车行驶过程中的气动阻力系数。首先通过风洞试验确定对整车气动阻力有重要影响的区域或部件,其次对气动阻力系数贡献值较大的部件或区域进行减阻优化。结果表明,前轮阻风板、尾灯和尾翼对整车气动阻力系数贡献值较大。对前轮阻风板的改型,有效降低正压区面积以及减弱车轮干扰阻力;对尾灯和尾翼的优化设计,改善了尾部负压区,缩短了分离流在后窗上部的再附着的距离。基于本征正交分解方法进行局部流场信息的提取和分析可知,1阶与2阶模态主要构成了该SUV尾流场的关键流态。经试验与仿真验证,相比于初始方案,气动优化组合设计减阻率可达7.5%。本文为新一代SUV改型与升级换代提供了理论基础与技术支持。 展开更多
关键词 汽车空气动力学 气动减阻 风洞试验 本征正交分解
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