Objective:To analyze the existing risks in breast milk management at the neonatal department and provide corresponding countermeasures.Methods:22 risk events were identified in 7 risk links in the process of bottle-fe...Objective:To analyze the existing risks in breast milk management at the neonatal department and provide corresponding countermeasures.Methods:22 risk events were identified in 7 risk links in the process of bottle-feeding of breast milk.Hazard Vulnerability Analysis based on the Kaiser model was applied to investigate and evaluate the risk events.Results:High-risk events include breast milk quality inspection,hand hygiene during collection,disinfection of collectors,cold chain management,hand hygiene during the reception,breast milk closed-loop management,and post-collection disposal.Root cause analysis of high-risk events was conducted and breast milk management strategies outside the hospital and within the neonatal department were proposed.Conclusion:Hazard Vulnerability Analysis based on the Kaiser model can identify and assess neonatal breast milk management risks effectively,which helps improve the management of neonatal breast milk.It is conducive to the safe development and promotion of bottle feeding of breast milk for neonates,ensuring the quality of medical services and the safety of children.展开更多
Kawasaki disease(KD)is a significant pediatric vasculitis known for its potential to cause severe coronary artery complications.Despite the effectiveness of initial treatments,such as intravenous immunoglobulin,KD pat...Kawasaki disease(KD)is a significant pediatric vasculitis known for its potential to cause severe coronary artery complications.Despite the effectiveness of initial treatments,such as intravenous immunoglobulin,KD patients can experience long-term cardiovascular issues,as evidenced by a recent case report of an adult who suffered a ST-segment elevation myocardial infarction due to previous KD in the World Journal of Clinical Cases.This editorial emphasizes the critical need for long-term management and regular surveillance to prevent such complications.By drawing on recent research and case studies,we advocate for a structured approach to follow-up care that includes routine cardiac evaluations and preventive measures.展开更多
This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal disease...This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal diseases.The study sheds light on how illness perception,anxiety,and depression significantly influence recovery outcomes.Hou et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor recovery.The article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for patients.The study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.展开更多
The objective of this paper is to demonstrate how assessment of seismic vulnerability can be effective in protection against earthquakes.Findings are reported from a case study in a densely populated urban area near a...The objective of this paper is to demonstrate how assessment of seismic vulnerability can be effective in protection against earthquakes.Findings are reported from a case study in a densely populated urban area near an active fault,utilizing practical methods and exact engineering data.Vulnerability factors were determined due to technical considerations,and a field campaign was performed to collect the required data.Multi-criteria decision making was carried out by means of an analytical hierarchy process including a fuzzy standardization.Earthquake scenarios were applied through an implicit vulnerability model.GIS was utilized and the results were analyzed by classifying the state of vulnerability in levels as very low,low,moderate,high,and very high.Seismic resilience was evaluated as vulnerabilities below the moderate state,being about 40% in an intensity of 6 Mercalli and less than 10% in 10 Mercalli.It is concluded that seismic resilience in the area studied is not acceptable,the area is vulnerable in the expected scenarios,and due to the high seismicity of the region,proper crisis management planning is required in parallel with attempts toward retrofitting.In this regard,an emergency map was developed with reference to the assessed vulnerabilities.展开更多
Essential for comprehensive and sustainable watershed management is the need to understand interactions between climate change predictions and landuse modifications in concert on ecohydrology. The Atlantic Canada regi...Essential for comprehensive and sustainable watershed management is the need to understand interactions between climate change predictions and landuse modifications in concert on ecohydrology. The Atlantic Canada region is expected to experience elevated rainfall due to climate change over the next century. We undertook a predictive modeling study of a watershed in rural Nova Scotia, Thomas Brook, to investigate the potential of riparian reforestation to mitigate the deleterious environmental effects projected to occur from future climate change. A Watershed Analysis Risk Management Framework (WARMF) model was used to predict increased watershed flows using data from projections of the Canadian Regional Climate Change Model. The cold climate-validated WARMF model, which has been used previously to simulate surface flow hydrology in many agricultural and mixed-use landscapes, was found to predict increases of 9% to 25% in flow for the Thomas Brook watershed throughout the rest of the century. A spatial, exposure-based model, used previously in several studies, was adopted for assessing changes in surface water vulnerability based on GIS land-use and landscape topography estimates of nutrient loading, sedimentation, runoff, wetland loss, and stream geomorphology. This model indicated that increases in drainage intensity and drainage sensitivity expected through the climate change WARMF model resulted in greater proportions (from 5% to 27%) of the Thomas Brook watershed area being classified as “High vulnerability” for impacting surface water quality. In terms of land use planning, implementation of runoff and nutrient entrapment techniques through low impact development may need to become increasingly required in order to maintain aquatic health. In terms of land-use management, empirically increasing the width of riparian forest buffers was projected to reduce the predicted areal extent of “High vulnerability”. However, widths of 90 m would be required in order to achieve the same degree of protection that presently exists. Our conclusions are that climate-proofing this watershed through riparian reforestation would come at a cost in terms of the extent of land needed to be set aside by being taken out of agricultural production or commercial forestry.展开更多
<div style="text-align:justify;"> <span style="font-family:Verdana;"></span>Recent trends show that in the coming decades, Kenya’s natural resources will continue to face signifi...<div style="text-align:justify;"> <span style="font-family:Verdana;"></span>Recent trends show that in the coming decades, Kenya’s natural resources will continue to face significant pressure due to both anthropogenic and natural stressors, and this will have greater negative impacts on socio-economic development including food security and livelihoods. Understanding the impacts of these stressors is an important step to developing coping and adaptation strategies at every level. The Water Towers of Kenya play a critical role in supplying ecosystems services such as water supply, timber and non-timber forest products and regulating services such as climate and water quantity and quality. To assess the vulnerability of the Water Towers to climate change, the study adopted the IPCC AR4 framework that defines vulnerability as a function of exposure, sensitivity, and adaptive capacity. The historical trends in rainfall indicate that the three Water Towers show a declining rainfall trend during the March-April-May (MAM) main rainy season, while the October-November-December (OND) short rainy season shows an increase. The temperature patterns are consistent with the domain having a common rising trend with a rate in the range of 0.3<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C to 0.5<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C per decade. Projection analysis considered three emissions scenarios: low-emission (mitigation) scenario (RCP2.6), a medium-level emission scenario (RCP4.5), and a high-emission (business as usual) scenario (RCP8.5). The results of the high-emission scenario show that the annual temperature over the Water Towers could rise by 3.0<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C to 3.5<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C by the 2050s (2036-2065) and 3.6<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C to 4.8<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C by the 2070s (2055-2085 results not presented), relative to the baseline period 1970-2000. The findings indicate that exposure, sensitivity, and adaptive capacity vary in magnitude, as well as spatially across the Water Towers. This is reflected in the spatially variable vulnerability index across the Water Towers. Overall vulnerability will increase in the water towers leading to erosion of the resilience of the exposed ecosystems and the communities that rely on ecosystem services these landscapes provide. </div>展开更多
The Philippines is one of the most hazard prone and vulnerable countries in the world to climate change effects due to its geographical location. Climate change is already happening and affecting many places causing h...The Philippines is one of the most hazard prone and vulnerable countries in the world to climate change effects due to its geographical location. Climate change is already happening and affecting many places causing huge problems to coastal ecosystems. Vulnerability and disaster assessment and mapping in coastal areas are essential tasks and undertakings for coastal disaster risk management. The objectives of this study were to assess the climate change vulnerability and disaster risks in the four municipalities (Sta. Cruz, Candelaria, Masinloc and Palauig) of Zambales and to determine the climate change community-based adaptation (CBA) and ecosystem-based adaptation (EBA) strategies. Remote sensing, GIS, secondary data gathering and key informant interview were used to assess vulnerability and disaster risks and mapping in the four municipalities. Survey questionnaire, focus group discussion and key informant interview were utilized in gathering data for the determination of climate change adaptation strategies. Using remote sensing technology, it was revealed that coastline changes have occurred in the shorelines of the four coastal municipalities after a decade. Sea level rise happened in Sta. Cruz and Masinloc, Zambales while there was build-up of soil in the coastline of Candelaria and Palauig, Zambales. Twelve hazard maps, 12 vulnerability maps and 12 disaster risk maps were generated for the three major disasters (flood, landslide, storm surge) in the four coastal municipalities. Based on the flood vulnerability and disaster risk assessment, the municipality of Palauig was found to be the most prone to flooding while the municipality of Candelaria was found to be the most vulnerable to landslide compared to other municipalities. All coastal barangays in the four municipalities were susceptible to storm surge. The four coastal municipalities were conducting community-based adaptation (CBA) and ecosystem-based adaptation (EBA) approaches in order to protect their coastal resources from the damaging impacts of climate change and improve the resilience of their local communities.展开更多
In Tunisia and particularly in Monastir region, groundwater constitutes the main source of water supply systems. A lot of problems are facing the water management authorities. In fact, the Moknine coastal aquifer high...In Tunisia and particularly in Monastir region, groundwater constitutes the main source of water supply systems. A lot of problems are facing the water management authorities. In fact, the Moknine coastal aquifer highlights several qualitative and quantitative anomalies due to the irrigated perimeters extension (Teboulba, Bekalta), releases of harmful products from the textile industry (Ksar Hellal and Moknine), intense overexploitation and seawater intrusion. Thus, for groundwater resources management, a Decision Support System (DSS) is developed for the Monastir region. This Decision Support System (DSS) brings together, on a digital support, the data descriptive and graphical component for groundwater management. It is a hydrogeological relational database joined with a Hydrogeological Information System for the Monastir region (HISM) which enables fast and effective processing of large volumes of spatial data from multiple sources. The implementation of the Hydrogeological Information System is assured using Object-Oriented Programming (OOP). The “Unified Modeling Language” (UML) is an Object-Oriented Design (OOD) methodology which is choiced for data modeling. The application interfaces have been developed in Visual Basic (VB.net) within the Integrated Development Environment (IDE) from Microsoft Visual Studio. “DotSpatial” library integrated is used to manage the geographic information layers. The HISM contains thematic layers acquired through the vectorization of 22 topographic and geologic maps (1/50,000 and 1/25,000) and the input of descriptive data from water well and pollution sources from field and laboratory studies. The HISM has a great management capacity;it ensures the conversion from the geographic coordinates to the planimetric coordinates. It allows adding, modifying, deleting and editing data (Rainfall, piezometric and geochemical). It also ensures the storage and editing of the digitized and/or generated cartographic database. This DSS was applied to the superficial coastal aquifer system of Moknine to define a conceptual model of groundwater functioning and assessment vulnerability to seawater intrusion.展开更多
With rapid development of the technology, many organizations depend more on the information than before and they will process mountains of information everyday. Hence, an information system is designed to facilitate m...With rapid development of the technology, many organizations depend more on the information than before and they will process mountains of information everyday. Hence, an information system is designed to facilitate managing information. Security is applied to insure data confidentiality, integrality and availability. In this process, risk can not be ignored. How can we analyze the degree of the risk we can accept to provide effective protection at reasonable costs with a great return on investment? Now many methodologies are proposed. In the paper, one method "Risk = Value * Threat * Vulnerability" is analyzed so that more people can have a basic understanding about the risk.展开更多
The widespread adoption of blockchain technology has led to the exploration of its numerous applications in various fields.Cryptographic algorithms and smart contracts are critical components of blockchain security.De...The widespread adoption of blockchain technology has led to the exploration of its numerous applications in various fields.Cryptographic algorithms and smart contracts are critical components of blockchain security.Despite the benefits of virtual currency,vulnerabilities in smart contracts have resulted in substantial losses to users.While researchers have identified these vulnerabilities and developed tools for detecting them,the accuracy of these tools is still far from satisfactory,with high false positive and false negative rates.In this paper,we propose a new method for detecting vulnerabilities in smart contracts using the BERT pre-training model,which can quickly and effectively process and detect smart contracts.More specifically,we preprocess and make symbol substitution in the contract,which can make the pre-training model better obtain contract features.We evaluate our method on four datasets and compare its performance with other deep learning models and vulnerability detection tools,demonstrating its superior accuracy.展开更多
Maintaining thermal comfort within the human body is crucial for optimal health and overall well-being.By merely broadening the setpoint of indoor temperatures,we could significantly slash energy usage in building hea...Maintaining thermal comfort within the human body is crucial for optimal health and overall well-being.By merely broadening the setpoint of indoor temperatures,we could significantly slash energy usage in building heating,ventilation,and air-conditioning systems.In recent years,there has been a surge in advancements in personal thermal management(PTM),aiming to regulate heat and moisture transfer within our immediate surroundings,clothing,and skin.The advent of PTM is driven by the rapid development in nano/micro-materials and energy science and engineering.An emerging research area in PTM is personal radiative thermal management(PRTM),which demonstrates immense potential with its high radiative heat transfer efficiency and ease of regulation.However,it is less taken into account in traditional textiles,and there currently lies a gap in our knowledge and understanding of PRTM.In this review,we aim to present a thorough analysis of advanced textile materials and technologies for PRTM.Specifically,we will introduce and discuss the underlying radiation heat transfer mechanisms,fabrication methods of textiles,and various indoor/outdoor applications in light of their different regulation functionalities,including radiative cooling,radiative heating,and dual-mode thermoregulation.Furthermore,we will shine a light on the current hurdles,propose potential strategies,and delve into future technology trends for PRTM with an emphasis on functionalities and applications.展开更多
Objective:To conduct a systematic literature review on urethral calculi in a contemporary cohort describing etiology,investigation,and management patterns.Methods:A systematic search of MEDLINE and Cochrane Central Re...Objective:To conduct a systematic literature review on urethral calculi in a contemporary cohort describing etiology,investigation,and management patterns.Methods:A systematic search of MEDLINE and Cochrane Central Register of Controlled Trials(CENTRAL)databases was performed.Articles,including case reports and case series on urethral calculi published between January 2000 and December 2019,were included.Full-text manuscripts were reviewed for clinical parameters including symptomatology,etiology,medical history,investigations,treatment,and outcomes.Data were collated and analyzed with univariate methods.Results:Seventy-four publications met inclusion criteria,reporting on 95 cases.Voiding symptoms(41.1%),pain(40.0%),and acute urinary retention(32.6%)were common presenting features.Urethral calculi were most often initially investigated using plain X-ray(63.2%),with almost all radio-opaque(98.3%).Urethral calculi were frequently associated with coexistent bladder or upper urinary tract calculi(16.8%)and underlying urethral pathology(53.7%)including diverticulum(33.7%)or stricture(13.7%).Urethral calculi were most commonly managed with external urethrolithotomy(31.6%),retrograde manipulation(22.1%),and endoscopic in situ lithotripsy(17.9%).Conclusion:This unique systematic review of urethral calculi provided a summary of clinical features and treatment trends with a suggested treatment algorithm.Management in contemporary urological practice should be according to calculus size,shape,anatomical location,and presence of urethral pathology.展开更多
Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and manageme...Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and management.It delves into host immune responses and reactivation’s delicate balance,spanning innate and adaptive immunity.Viral factors’disruption of this balance,as are interac-tions between viral antigens,immune cells,cytokine networks,and immune checkpoint pathways,are examined.Notably,the roles of T cells,natural killer cells,and antigen-presenting cells are discussed,highlighting their influence on disease progression.HBV reactivation’s impact on disease severity,hepatic flares,liver fibrosis progression,and hepatocellular carcinoma is detailed.Management strategies,including anti-viral and immunomodulatory approaches,are critically analyzed.The role of prophylactic anti-viral therapy during immunosuppressive treatments is explored alongside novel immunotherapeutic interventions to restore immune control and prevent reactivation.In conclusion,this compre-hensive review furnishes a holistic view of the immunological mechanisms that propel HBV reactivation.With a dedicated focus on understanding its implic-ations for disease progression and the prospects of efficient management stra-tegies,this article contributes significantly to the knowledge base.The more profound insights into the intricate interactions between viral elements and the immune system will inform evidence-based approaches,ultimately enhancing disease management and elevating patient outcomes.The dynamic landscape of management strategies is critically scrutinized,spanning anti-viral and immunomodulatory approaches.The role of prophylactic anti-viral therapy in preventing reactivation during immunosuppressive treatments and the potential of innovative immunotherapeutic interventions to restore immune control and proactively deter reactivation.展开更多
AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a tota...AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a total of 119 patients completed a Patient Satisfaction Questionnaire-18 and a sociodemographic questionnaire.Clinical data was obtained from the case management system.Follow-up adherence was defined as completing each follow-up within±30d of the scheduled time set by ophthalmologists during the study period.RESULTS:Average satisfaction scored 78.65±7,with an average of 4.39±0.58 across the seven dimensions.Age negatively correlated with satisfaction(P=0.008),whilst patients with follow-up duration of 2 or more years reported higher satisfaction(P=0.045).Multivariate logistics regression analysis revealed that longer follow-up durations were associated with lower follow-up adherence(OR=0.97,95%CI,0.95-1.00,P=0.044).Additionally,patients with suspected glaucoma(OR=2.72,95%CI,1.03-7.20,P=0.044)and those with an annual income over 100000 Chinese yuan demonstrated higher adherence(OR=5.57,95%CI,1.00-30.89,P=0.049).CONCLUSION:The case management model proves effective for glaucoma patients,with positive adherence rates.The implementation of this model can be optimized in the future based on the identified factors and extended to glaucoma patients in more hospitals.展开更多
Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery systems.Inorganic phase chan...Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery systems.Inorganic phase change material(PCM)with nonflammability has the potential to achieve this dual function.This study proposed an encapsulated inorganic phase change material(EPCM)with a heat transfer enhancement for battery systems,where Na_(2)HPO_(4)·12H_(2)O was used as the core PCM encapsulated by silica and the additive of carbon nanotube(CNT)was applied to enhance the thermal conductivity.The microstructure and thermal properties of the EPCM/CNT were analyzed by a series of characterization tests.Two different incorporating methods of CNT were compared and the proper CNT adding amount was also studied.After preparation,the battery thermal management performance and TR propagation mitigation effects of EPCM/CNT were further investigated on the battery modules.The experimental results of thermal management tests showed that EPCM/CNT not only slowed down the temperature rising of the module but also improved the temperature uniformity during normal operation.The peak battery temperature decreased from 76℃to 61.2℃at 2 C discharge rate and the temperature difference was controlled below 3℃.Moreover,the results of TR propagation tests demonstrated that nonflammable EPCM/CNT with good heat absorption could work as a TR barrier,which exhibited effective mitigation on TR and TR propagation.The trigger time of three cells was successfully delayed by 129,474 and 551 s,respectively and the propagation intervals were greatly extended as well.展开更多
BACKGROUND Regarding the incidence of malignant tumors in China,the incidence of liver cancer ranks fourth,second only to lung,gastric,and esophageal cancers.The case fatality rate ranks third after lung and cervical ...BACKGROUND Regarding the incidence of malignant tumors in China,the incidence of liver cancer ranks fourth,second only to lung,gastric,and esophageal cancers.The case fatality rate ranks third after lung and cervical cancer.In a previous study,the whole-process management model was applied to patients with breast cancer,which effectively reduced their negative emotions and improved treatment adherence and nursing satisfaction.METHODS In this single-center,randomized,controlled study,60 randomly selected patients with liver cancer who had been admitted to our hospital from January 2021 to January 2022 were randomly divided into an observation group(n=30),who received whole-process case management on the basis of routine nursing mea-sures,and a control group(n=30),who were given routine nursing measures.We compared differences between the two groups in terms of anxiety,depression,the level of hope,self-care ability,symptom distress,sleep quality,and quality of life.RESULTS Post-intervention,Hamilton anxiety scale,Hamilton depression scale,memory symptom assessment scale,and Pittsburgh sleep quality index scores in both groups were lower than those pre-intervention,and the observation group had lower scores than the control group(P<0.05).Herth hope index,self-care ability assessment scale-revision in Chinese,and quality of life measurement scale for patients with liver cancer scores in both groups were higher than those pre-intervention,with higher scores in the observation group compared with the control group(P<0.05).CONCLUSION Whole-process case management can effectively reduce anxiety and depression in patients with liver cancer,alleviate symptoms and problems,and improve the level of hope,self-care ability,sleep quality,and quality of life,as well as provide feasible nursing alternatives for patients with liver cancer.展开更多
BACKGROUND Colorectal signet-ring cell carcinoma(CSRCC)is a rare clinical entity which accounts for approximately 1%of all colorectal cancers.Although multiple studies concerning this specific topic have been publishe...BACKGROUND Colorectal signet-ring cell carcinoma(CSRCC)is a rare clinical entity which accounts for approximately 1%of all colorectal cancers.Although multiple studies concerning this specific topic have been published in the past decades,the pathogenesis,associated risk factors,and potential implications on treatment are still poorly understood.Besides the low incidence,historically confusing histological criteria have resulted in confusing data.Nevertheless,the rising incidence of CSRCC along with relatively young age at presentation and associated dismal prognosis,highlight the actual interest to synthesize the known literature regarding CSRCC.AIM To provide an updated overview of risk factors,prognosis,and management of CSRCC.METHODS A literature search in the MEDLINE/PubMed database was conducted with the following search terms used:‘Signet ring cell carcinoma’and‘colorectal’.Studies in English language,published after January 1980,were included.Studies included in the qualitative synthesis were evaluated for content concerning epidemiology,risk factors,and clinical,diagnostic,histological,and molecular features,as well as metastatic pattern and therapeutic management.If possible,presented data was extracted in order to present a more detailed overview of the literature.RESULTS In total,67 articles were included for qualitative analysis,of which 54 were eligible for detailed data extraction.CSRCC has a reported incidence between 0.1%-2.4%and frequently presents with advanced disease stage at the time of diagnosis.CSRCC is associated with an impaired overall survival(5-year OS:0%-46%)and a worse stagecorrected outcome compared to mucinous and not otherwise specified adenocarcinoma.The systematic use of exploratory laparoscopy to determine the presence of peritoneal metastases has been advised.Surgery is the mainstay of treatment,although the rates of curative resection in CSRCC(21%-82%)are lower compared to those in other histological types.In case of peritoneal metastasis,cytoreductive surgery with hyperthermic intraperitoneal chemotherapy should only be proposed in selected patients.CONCLUSION CSRCC is a rare clinical entity most often characterized by young age and advanced disease at presentation.As such,diagnostic modalities and therapeutic approach should be tailored accordingly.展开更多
The detection of software vulnerabilities written in C and C++languages takes a lot of attention and interest today.This paper proposes a new framework called DrCSE to improve software vulnerability detection.It uses ...The detection of software vulnerabilities written in C and C++languages takes a lot of attention and interest today.This paper proposes a new framework called DrCSE to improve software vulnerability detection.It uses an intelligent computation technique based on the combination of two methods:Rebalancing data and representation learning to analyze and evaluate the code property graph(CPG)of the source code for detecting abnormal behavior of software vulnerabilities.To do that,DrCSE performs a combination of 3 main processing techniques:(i)building the source code feature profiles,(ii)rebalancing data,and(iii)contrastive learning.In which,the method(i)extracts the source code’s features based on the vertices and edges of the CPG.The method of rebalancing data has the function of supporting the training process by balancing the experimental dataset.Finally,contrastive learning techniques learn the important features of the source code by finding and pulling similar ones together while pushing the outliers away.The experiment part of this paper demonstrates the superiority of the DrCSE Framework for detecting source code security vulnerabilities using the Verum dataset.As a result,the method proposed in the article has brought a pretty good performance in all metrics,especially the Precision and Recall scores of 39.35%and 69.07%,respectively,proving the efficiency of the DrCSE Framework.It performs better than other approaches,with a 5%boost in Precision and a 5%boost in Recall.Overall,this is considered the best research result for the software vulnerability detection problem using the Verum dataset according to our survey to date.展开更多
BACKGROUND Cerebral infarction,previously referred to as cerebral infarction or ischemic stroke,refers to the localized brain tissue experiencing ischemic necrosis or softening due to disorders in brain blood supply,i...BACKGROUND Cerebral infarction,previously referred to as cerebral infarction or ischemic stroke,refers to the localized brain tissue experiencing ischemic necrosis or softening due to disorders in brain blood supply,ischemia,and hypoxia.The precision rehabilitation nursing model for chronic disease management is a continuous,fixed,orderly,and efficient nursing model aimed at standardizing the clinical nursing process,reducing the wastage of medical resources,and improving the quality of medical services.AIM To analyze the value of a precise rehabilitation nursing model for chronic disease management in patients with cerebral infarction.METHODS Patients(n=124)admitted to our hospital with cerebral infarction between November 2019 and November 2021 were enrolled as the study subjects.The random number table method was used to divide them into a conventional nursing intervention group(n=61)and a model nursing intervention group(n=63).Changes in the nursing index for the two groups were compared after conventional nursing intervention and precise rehabilitation intervention nursing for chronic disease management.RESULTS Compared with the conventional intervention group,the model intervention group had a shorter time to clinical symptom relief(P<0.05),lower Hamilton Anxiety Scale and Hamilton Depression Scale scores,a lower incidence of total complications(P<0.05),a higher disease knowledge mastery rate,higher safety and quality,and a higher overall nursing satisfaction rate(P<0.05).CONCLUSION The precision rehabilitation nursing model for chronic disease management improves the clinical symptoms of patients with cerebral infarction,reducing the incidence of total complications and improving the clinical outcome of patients,and is worthy of application in clinical practice.展开更多
Jeneberang watershed is vital,particularly for people living in Gowa Regency(South Sulawesi Province,Indonesia),who benefit from its many advantages.Landslides and floods occur every year in the Jeneberang watershed,s...Jeneberang watershed is vital,particularly for people living in Gowa Regency(South Sulawesi Province,Indonesia),who benefit from its many advantages.Landslides and floods occur every year in the Jeneberang watershed,so it is imperative to understand the socio-economic vulnerability of this region.This research aims to identify the vulnerability level of the Jeneberang watershed so that the government can prioritize areas with high vulnerability level and formulate effective strategies to reduce these the vulnerability.Specifically,this study was conducted in 12 districts located in the Jeneberang watershed.The primary data were collected from questionnaires completed by community members,community leaders,and various stakeholders,and the secondary data were from the Landsat satellite imagery in 2020,the Badan Push Statistic of Gowa Regency,and some governmental agencies.The socio-economic vulnerability variables were determined using the Multiple Criteria Decision Analysis(MCDA)method,and each variable was weighted and analyzed using the Geographical Information System(GIS).The study reveals that the levels of socio-economic vulnerability are affected by variables such as population density,vulnerable groups(disabled people,elderly people,and young people),road network and settlement,percentage of poor people,and productive land area in the Jeneberang watershed.Moreover,all of the 12 districts in the Jeneberang watershed are included in the medium vulnerability level,with the mean percentage of socio-economic vulnerability around 50.92%.The socio-economic vulnerability of Bajeng,Pallangga,and Somba Opu districts is categorized at high level,the socio-economic vulnerability of Bungaya,Parangloe,and Tombolo Pao districts is classified as medium level,and the remaining 6 districts(Barombong,Bontolempangan,Bontomarannu,Manuju,Parigi,and Tinggimoncong)are ranked as low socio-economic vulnerability.This study can help policy-makers to formulate strategy that contributes to the protection of biodiversity and sustainable development of the Jeneberang watershed,while improving disaster resilience and preparedness of the watershed.展开更多
文摘Objective:To analyze the existing risks in breast milk management at the neonatal department and provide corresponding countermeasures.Methods:22 risk events were identified in 7 risk links in the process of bottle-feeding of breast milk.Hazard Vulnerability Analysis based on the Kaiser model was applied to investigate and evaluate the risk events.Results:High-risk events include breast milk quality inspection,hand hygiene during collection,disinfection of collectors,cold chain management,hand hygiene during the reception,breast milk closed-loop management,and post-collection disposal.Root cause analysis of high-risk events was conducted and breast milk management strategies outside the hospital and within the neonatal department were proposed.Conclusion:Hazard Vulnerability Analysis based on the Kaiser model can identify and assess neonatal breast milk management risks effectively,which helps improve the management of neonatal breast milk.It is conducive to the safe development and promotion of bottle feeding of breast milk for neonates,ensuring the quality of medical services and the safety of children.
文摘Kawasaki disease(KD)is a significant pediatric vasculitis known for its potential to cause severe coronary artery complications.Despite the effectiveness of initial treatments,such as intravenous immunoglobulin,KD patients can experience long-term cardiovascular issues,as evidenced by a recent case report of an adult who suffered a ST-segment elevation myocardial infarction due to previous KD in the World Journal of Clinical Cases.This editorial emphasizes the critical need for long-term management and regular surveillance to prevent such complications.By drawing on recent research and case studies,we advocate for a structured approach to follow-up care that includes routine cardiac evaluations and preventive measures.
基金Supported by National Research Foundation of Korea,No.NRF-2021S1A5A8062526.
文摘This article provides a comprehensive analysis of the study by Hou et al,focusing on the complex interplay between psychological and physical factors in the postoperative recovery(POR)of patients with perianal diseases.The study sheds light on how illness perception,anxiety,and depression significantly influence recovery outcomes.Hou et al developed a predictive model that demonstrated high accuracy in identifying patients at risk of poor recovery.The article explores the critical role of pre-operative psychological assessment,highlighting the need for mental health support and personalized recovery plans in enhancing POR quality.A multidisciplinary approach,integrating mental health professionals with surgeons,anesthesiologists,and other specialists,is emphasized to ensure comprehensive care for patients.The study’s findings serve as a call to integrate psychological care into surgical practice to optimize outcomes for patients with perianal diseases.
文摘The objective of this paper is to demonstrate how assessment of seismic vulnerability can be effective in protection against earthquakes.Findings are reported from a case study in a densely populated urban area near an active fault,utilizing practical methods and exact engineering data.Vulnerability factors were determined due to technical considerations,and a field campaign was performed to collect the required data.Multi-criteria decision making was carried out by means of an analytical hierarchy process including a fuzzy standardization.Earthquake scenarios were applied through an implicit vulnerability model.GIS was utilized and the results were analyzed by classifying the state of vulnerability in levels as very low,low,moderate,high,and very high.Seismic resilience was evaluated as vulnerabilities below the moderate state,being about 40% in an intensity of 6 Mercalli and less than 10% in 10 Mercalli.It is concluded that seismic resilience in the area studied is not acceptable,the area is vulnerable in the expected scenarios,and due to the high seismicity of the region,proper crisis management planning is required in parallel with attempts toward retrofitting.In this regard,an emergency map was developed with reference to the assessed vulnerabilities.
文摘Essential for comprehensive and sustainable watershed management is the need to understand interactions between climate change predictions and landuse modifications in concert on ecohydrology. The Atlantic Canada region is expected to experience elevated rainfall due to climate change over the next century. We undertook a predictive modeling study of a watershed in rural Nova Scotia, Thomas Brook, to investigate the potential of riparian reforestation to mitigate the deleterious environmental effects projected to occur from future climate change. A Watershed Analysis Risk Management Framework (WARMF) model was used to predict increased watershed flows using data from projections of the Canadian Regional Climate Change Model. The cold climate-validated WARMF model, which has been used previously to simulate surface flow hydrology in many agricultural and mixed-use landscapes, was found to predict increases of 9% to 25% in flow for the Thomas Brook watershed throughout the rest of the century. A spatial, exposure-based model, used previously in several studies, was adopted for assessing changes in surface water vulnerability based on GIS land-use and landscape topography estimates of nutrient loading, sedimentation, runoff, wetland loss, and stream geomorphology. This model indicated that increases in drainage intensity and drainage sensitivity expected through the climate change WARMF model resulted in greater proportions (from 5% to 27%) of the Thomas Brook watershed area being classified as “High vulnerability” for impacting surface water quality. In terms of land use planning, implementation of runoff and nutrient entrapment techniques through low impact development may need to become increasingly required in order to maintain aquatic health. In terms of land-use management, empirically increasing the width of riparian forest buffers was projected to reduce the predicted areal extent of “High vulnerability”. However, widths of 90 m would be required in order to achieve the same degree of protection that presently exists. Our conclusions are that climate-proofing this watershed through riparian reforestation would come at a cost in terms of the extent of land needed to be set aside by being taken out of agricultural production or commercial forestry.
文摘<div style="text-align:justify;"> <span style="font-family:Verdana;"></span>Recent trends show that in the coming decades, Kenya’s natural resources will continue to face significant pressure due to both anthropogenic and natural stressors, and this will have greater negative impacts on socio-economic development including food security and livelihoods. Understanding the impacts of these stressors is an important step to developing coping and adaptation strategies at every level. The Water Towers of Kenya play a critical role in supplying ecosystems services such as water supply, timber and non-timber forest products and regulating services such as climate and water quantity and quality. To assess the vulnerability of the Water Towers to climate change, the study adopted the IPCC AR4 framework that defines vulnerability as a function of exposure, sensitivity, and adaptive capacity. The historical trends in rainfall indicate that the three Water Towers show a declining rainfall trend during the March-April-May (MAM) main rainy season, while the October-November-December (OND) short rainy season shows an increase. The temperature patterns are consistent with the domain having a common rising trend with a rate in the range of 0.3<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C to 0.5<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C per decade. Projection analysis considered three emissions scenarios: low-emission (mitigation) scenario (RCP2.6), a medium-level emission scenario (RCP4.5), and a high-emission (business as usual) scenario (RCP8.5). The results of the high-emission scenario show that the annual temperature over the Water Towers could rise by 3.0<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C to 3.5<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C by the 2050s (2036-2065) and 3.6<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C to 4.8<span style="color:#4F4F4F;font-family:-apple-system, "font-size:14px;white-space:normal;background-color:#FFFFFF;">°</span>C by the 2070s (2055-2085 results not presented), relative to the baseline period 1970-2000. The findings indicate that exposure, sensitivity, and adaptive capacity vary in magnitude, as well as spatially across the Water Towers. This is reflected in the spatially variable vulnerability index across the Water Towers. Overall vulnerability will increase in the water towers leading to erosion of the resilience of the exposed ecosystems and the communities that rely on ecosystem services these landscapes provide. </div>
文摘The Philippines is one of the most hazard prone and vulnerable countries in the world to climate change effects due to its geographical location. Climate change is already happening and affecting many places causing huge problems to coastal ecosystems. Vulnerability and disaster assessment and mapping in coastal areas are essential tasks and undertakings for coastal disaster risk management. The objectives of this study were to assess the climate change vulnerability and disaster risks in the four municipalities (Sta. Cruz, Candelaria, Masinloc and Palauig) of Zambales and to determine the climate change community-based adaptation (CBA) and ecosystem-based adaptation (EBA) strategies. Remote sensing, GIS, secondary data gathering and key informant interview were used to assess vulnerability and disaster risks and mapping in the four municipalities. Survey questionnaire, focus group discussion and key informant interview were utilized in gathering data for the determination of climate change adaptation strategies. Using remote sensing technology, it was revealed that coastline changes have occurred in the shorelines of the four coastal municipalities after a decade. Sea level rise happened in Sta. Cruz and Masinloc, Zambales while there was build-up of soil in the coastline of Candelaria and Palauig, Zambales. Twelve hazard maps, 12 vulnerability maps and 12 disaster risk maps were generated for the three major disasters (flood, landslide, storm surge) in the four coastal municipalities. Based on the flood vulnerability and disaster risk assessment, the municipality of Palauig was found to be the most prone to flooding while the municipality of Candelaria was found to be the most vulnerable to landslide compared to other municipalities. All coastal barangays in the four municipalities were susceptible to storm surge. The four coastal municipalities were conducting community-based adaptation (CBA) and ecosystem-based adaptation (EBA) approaches in order to protect their coastal resources from the damaging impacts of climate change and improve the resilience of their local communities.
文摘In Tunisia and particularly in Monastir region, groundwater constitutes the main source of water supply systems. A lot of problems are facing the water management authorities. In fact, the Moknine coastal aquifer highlights several qualitative and quantitative anomalies due to the irrigated perimeters extension (Teboulba, Bekalta), releases of harmful products from the textile industry (Ksar Hellal and Moknine), intense overexploitation and seawater intrusion. Thus, for groundwater resources management, a Decision Support System (DSS) is developed for the Monastir region. This Decision Support System (DSS) brings together, on a digital support, the data descriptive and graphical component for groundwater management. It is a hydrogeological relational database joined with a Hydrogeological Information System for the Monastir region (HISM) which enables fast and effective processing of large volumes of spatial data from multiple sources. The implementation of the Hydrogeological Information System is assured using Object-Oriented Programming (OOP). The “Unified Modeling Language” (UML) is an Object-Oriented Design (OOD) methodology which is choiced for data modeling. The application interfaces have been developed in Visual Basic (VB.net) within the Integrated Development Environment (IDE) from Microsoft Visual Studio. “DotSpatial” library integrated is used to manage the geographic information layers. The HISM contains thematic layers acquired through the vectorization of 22 topographic and geologic maps (1/50,000 and 1/25,000) and the input of descriptive data from water well and pollution sources from field and laboratory studies. The HISM has a great management capacity;it ensures the conversion from the geographic coordinates to the planimetric coordinates. It allows adding, modifying, deleting and editing data (Rainfall, piezometric and geochemical). It also ensures the storage and editing of the digitized and/or generated cartographic database. This DSS was applied to the superficial coastal aquifer system of Moknine to define a conceptual model of groundwater functioning and assessment vulnerability to seawater intrusion.
文摘With rapid development of the technology, many organizations depend more on the information than before and they will process mountains of information everyday. Hence, an information system is designed to facilitate managing information. Security is applied to insure data confidentiality, integrality and availability. In this process, risk can not be ignored. How can we analyze the degree of the risk we can accept to provide effective protection at reasonable costs with a great return on investment? Now many methodologies are proposed. In the paper, one method "Risk = Value * Threat * Vulnerability" is analyzed so that more people can have a basic understanding about the risk.
基金supported by the National Key Research and Development Plan in China(Grant No.2020YFB1005500)。
文摘The widespread adoption of blockchain technology has led to the exploration of its numerous applications in various fields.Cryptographic algorithms and smart contracts are critical components of blockchain security.Despite the benefits of virtual currency,vulnerabilities in smart contracts have resulted in substantial losses to users.While researchers have identified these vulnerabilities and developed tools for detecting them,the accuracy of these tools is still far from satisfactory,with high false positive and false negative rates.In this paper,we propose a new method for detecting vulnerabilities in smart contracts using the BERT pre-training model,which can quickly and effectively process and detect smart contracts.More specifically,we preprocess and make symbol substitution in the contract,which can make the pre-training model better obtain contract features.We evaluate our method on four datasets and compare its performance with other deep learning models and vulnerability detection tools,demonstrating its superior accuracy.
基金support from the Research Grants Council of the Hong Kong Special Administrative Region,China(PolyU152052/21E)Green Tech Fund of Hong Kong(Project No.:GTF202220106)+1 种基金Innovation and Technology Fund of the Hong Kong Special Administrative Region,China(ITP/018/21TP)PolyU Endowed Young Scholars Scheme(Project No.:84CC).
文摘Maintaining thermal comfort within the human body is crucial for optimal health and overall well-being.By merely broadening the setpoint of indoor temperatures,we could significantly slash energy usage in building heating,ventilation,and air-conditioning systems.In recent years,there has been a surge in advancements in personal thermal management(PTM),aiming to regulate heat and moisture transfer within our immediate surroundings,clothing,and skin.The advent of PTM is driven by the rapid development in nano/micro-materials and energy science and engineering.An emerging research area in PTM is personal radiative thermal management(PRTM),which demonstrates immense potential with its high radiative heat transfer efficiency and ease of regulation.However,it is less taken into account in traditional textiles,and there currently lies a gap in our knowledge and understanding of PRTM.In this review,we aim to present a thorough analysis of advanced textile materials and technologies for PRTM.Specifically,we will introduce and discuss the underlying radiation heat transfer mechanisms,fabrication methods of textiles,and various indoor/outdoor applications in light of their different regulation functionalities,including radiative cooling,radiative heating,and dual-mode thermoregulation.Furthermore,we will shine a light on the current hurdles,propose potential strategies,and delve into future technology trends for PRTM with an emphasis on functionalities and applications.
文摘Objective:To conduct a systematic literature review on urethral calculi in a contemporary cohort describing etiology,investigation,and management patterns.Methods:A systematic search of MEDLINE and Cochrane Central Register of Controlled Trials(CENTRAL)databases was performed.Articles,including case reports and case series on urethral calculi published between January 2000 and December 2019,were included.Full-text manuscripts were reviewed for clinical parameters including symptomatology,etiology,medical history,investigations,treatment,and outcomes.Data were collated and analyzed with univariate methods.Results:Seventy-four publications met inclusion criteria,reporting on 95 cases.Voiding symptoms(41.1%),pain(40.0%),and acute urinary retention(32.6%)were common presenting features.Urethral calculi were most often initially investigated using plain X-ray(63.2%),with almost all radio-opaque(98.3%).Urethral calculi were frequently associated with coexistent bladder or upper urinary tract calculi(16.8%)and underlying urethral pathology(53.7%)including diverticulum(33.7%)or stricture(13.7%).Urethral calculi were most commonly managed with external urethrolithotomy(31.6%),retrograde manipulation(22.1%),and endoscopic in situ lithotripsy(17.9%).Conclusion:This unique systematic review of urethral calculi provided a summary of clinical features and treatment trends with a suggested treatment algorithm.Management in contemporary urological practice should be according to calculus size,shape,anatomical location,and presence of urethral pathology.
文摘Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and management.It delves into host immune responses and reactivation’s delicate balance,spanning innate and adaptive immunity.Viral factors’disruption of this balance,as are interac-tions between viral antigens,immune cells,cytokine networks,and immune checkpoint pathways,are examined.Notably,the roles of T cells,natural killer cells,and antigen-presenting cells are discussed,highlighting their influence on disease progression.HBV reactivation’s impact on disease severity,hepatic flares,liver fibrosis progression,and hepatocellular carcinoma is detailed.Management strategies,including anti-viral and immunomodulatory approaches,are critically analyzed.The role of prophylactic anti-viral therapy during immunosuppressive treatments is explored alongside novel immunotherapeutic interventions to restore immune control and prevent reactivation.In conclusion,this compre-hensive review furnishes a holistic view of the immunological mechanisms that propel HBV reactivation.With a dedicated focus on understanding its implic-ations for disease progression and the prospects of efficient management stra-tegies,this article contributes significantly to the knowledge base.The more profound insights into the intricate interactions between viral elements and the immune system will inform evidence-based approaches,ultimately enhancing disease management and elevating patient outcomes.The dynamic landscape of management strategies is critically scrutinized,spanning anti-viral and immunomodulatory approaches.The role of prophylactic anti-viral therapy in preventing reactivation during immunosuppressive treatments and the potential of innovative immunotherapeutic interventions to restore immune control and proactively deter reactivation.
基金Supported by the Key Innovation and Guidance Program of the Eye Hospital,School of Ophthalmology&Optometry,Wenzhou Medical University(No.YNZD2201903)the Scientific Research Foundation of the Eye Hospital,School of Ophthalmology&Optometry,Wenzhou Medical University(No.KYQD20180306)the Nursing Project of the Eye Hospital of Wenzhou Medical University(No.YNHL2201908).
文摘AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a total of 119 patients completed a Patient Satisfaction Questionnaire-18 and a sociodemographic questionnaire.Clinical data was obtained from the case management system.Follow-up adherence was defined as completing each follow-up within±30d of the scheduled time set by ophthalmologists during the study period.RESULTS:Average satisfaction scored 78.65±7,with an average of 4.39±0.58 across the seven dimensions.Age negatively correlated with satisfaction(P=0.008),whilst patients with follow-up duration of 2 or more years reported higher satisfaction(P=0.045).Multivariate logistics regression analysis revealed that longer follow-up durations were associated with lower follow-up adherence(OR=0.97,95%CI,0.95-1.00,P=0.044).Additionally,patients with suspected glaucoma(OR=2.72,95%CI,1.03-7.20,P=0.044)and those with an annual income over 100000 Chinese yuan demonstrated higher adherence(OR=5.57,95%CI,1.00-30.89,P=0.049).CONCLUSION:The case management model proves effective for glaucoma patients,with positive adherence rates.The implementation of this model can be optimized in the future based on the identified factors and extended to glaucoma patients in more hospitals.
基金financially supported by the National Key Research and Development Program(Grant No.2022YFE0207400)the National Natural Science Foundation of China(Grant No.U22A20168 and 52174225)。
文摘Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery systems.Inorganic phase change material(PCM)with nonflammability has the potential to achieve this dual function.This study proposed an encapsulated inorganic phase change material(EPCM)with a heat transfer enhancement for battery systems,where Na_(2)HPO_(4)·12H_(2)O was used as the core PCM encapsulated by silica and the additive of carbon nanotube(CNT)was applied to enhance the thermal conductivity.The microstructure and thermal properties of the EPCM/CNT were analyzed by a series of characterization tests.Two different incorporating methods of CNT were compared and the proper CNT adding amount was also studied.After preparation,the battery thermal management performance and TR propagation mitigation effects of EPCM/CNT were further investigated on the battery modules.The experimental results of thermal management tests showed that EPCM/CNT not only slowed down the temperature rising of the module but also improved the temperature uniformity during normal operation.The peak battery temperature decreased from 76℃to 61.2℃at 2 C discharge rate and the temperature difference was controlled below 3℃.Moreover,the results of TR propagation tests demonstrated that nonflammable EPCM/CNT with good heat absorption could work as a TR barrier,which exhibited effective mitigation on TR and TR propagation.The trigger time of three cells was successfully delayed by 129,474 and 551 s,respectively and the propagation intervals were greatly extended as well.
基金This study protocol was approved by the General Hospital of the Yangtze River Shipping,and all the families have voluntarily participated in the study and have signed informed consent forms.
文摘BACKGROUND Regarding the incidence of malignant tumors in China,the incidence of liver cancer ranks fourth,second only to lung,gastric,and esophageal cancers.The case fatality rate ranks third after lung and cervical cancer.In a previous study,the whole-process management model was applied to patients with breast cancer,which effectively reduced their negative emotions and improved treatment adherence and nursing satisfaction.METHODS In this single-center,randomized,controlled study,60 randomly selected patients with liver cancer who had been admitted to our hospital from January 2021 to January 2022 were randomly divided into an observation group(n=30),who received whole-process case management on the basis of routine nursing mea-sures,and a control group(n=30),who were given routine nursing measures.We compared differences between the two groups in terms of anxiety,depression,the level of hope,self-care ability,symptom distress,sleep quality,and quality of life.RESULTS Post-intervention,Hamilton anxiety scale,Hamilton depression scale,memory symptom assessment scale,and Pittsburgh sleep quality index scores in both groups were lower than those pre-intervention,and the observation group had lower scores than the control group(P<0.05).Herth hope index,self-care ability assessment scale-revision in Chinese,and quality of life measurement scale for patients with liver cancer scores in both groups were higher than those pre-intervention,with higher scores in the observation group compared with the control group(P<0.05).CONCLUSION Whole-process case management can effectively reduce anxiety and depression in patients with liver cancer,alleviate symptoms and problems,and improve the level of hope,self-care ability,sleep quality,and quality of life,as well as provide feasible nursing alternatives for patients with liver cancer.
文摘BACKGROUND Colorectal signet-ring cell carcinoma(CSRCC)is a rare clinical entity which accounts for approximately 1%of all colorectal cancers.Although multiple studies concerning this specific topic have been published in the past decades,the pathogenesis,associated risk factors,and potential implications on treatment are still poorly understood.Besides the low incidence,historically confusing histological criteria have resulted in confusing data.Nevertheless,the rising incidence of CSRCC along with relatively young age at presentation and associated dismal prognosis,highlight the actual interest to synthesize the known literature regarding CSRCC.AIM To provide an updated overview of risk factors,prognosis,and management of CSRCC.METHODS A literature search in the MEDLINE/PubMed database was conducted with the following search terms used:‘Signet ring cell carcinoma’and‘colorectal’.Studies in English language,published after January 1980,were included.Studies included in the qualitative synthesis were evaluated for content concerning epidemiology,risk factors,and clinical,diagnostic,histological,and molecular features,as well as metastatic pattern and therapeutic management.If possible,presented data was extracted in order to present a more detailed overview of the literature.RESULTS In total,67 articles were included for qualitative analysis,of which 54 were eligible for detailed data extraction.CSRCC has a reported incidence between 0.1%-2.4%and frequently presents with advanced disease stage at the time of diagnosis.CSRCC is associated with an impaired overall survival(5-year OS:0%-46%)and a worse stagecorrected outcome compared to mucinous and not otherwise specified adenocarcinoma.The systematic use of exploratory laparoscopy to determine the presence of peritoneal metastases has been advised.Surgery is the mainstay of treatment,although the rates of curative resection in CSRCC(21%-82%)are lower compared to those in other histological types.In case of peritoneal metastasis,cytoreductive surgery with hyperthermic intraperitoneal chemotherapy should only be proposed in selected patients.CONCLUSION CSRCC is a rare clinical entity most often characterized by young age and advanced disease at presentation.As such,diagnostic modalities and therapeutic approach should be tailored accordingly.
文摘The detection of software vulnerabilities written in C and C++languages takes a lot of attention and interest today.This paper proposes a new framework called DrCSE to improve software vulnerability detection.It uses an intelligent computation technique based on the combination of two methods:Rebalancing data and representation learning to analyze and evaluate the code property graph(CPG)of the source code for detecting abnormal behavior of software vulnerabilities.To do that,DrCSE performs a combination of 3 main processing techniques:(i)building the source code feature profiles,(ii)rebalancing data,and(iii)contrastive learning.In which,the method(i)extracts the source code’s features based on the vertices and edges of the CPG.The method of rebalancing data has the function of supporting the training process by balancing the experimental dataset.Finally,contrastive learning techniques learn the important features of the source code by finding and pulling similar ones together while pushing the outliers away.The experiment part of this paper demonstrates the superiority of the DrCSE Framework for detecting source code security vulnerabilities using the Verum dataset.As a result,the method proposed in the article has brought a pretty good performance in all metrics,especially the Precision and Recall scores of 39.35%and 69.07%,respectively,proving the efficiency of the DrCSE Framework.It performs better than other approaches,with a 5%boost in Precision and a 5%boost in Recall.Overall,this is considered the best research result for the software vulnerability detection problem using the Verum dataset according to our survey to date.
文摘BACKGROUND Cerebral infarction,previously referred to as cerebral infarction or ischemic stroke,refers to the localized brain tissue experiencing ischemic necrosis or softening due to disorders in brain blood supply,ischemia,and hypoxia.The precision rehabilitation nursing model for chronic disease management is a continuous,fixed,orderly,and efficient nursing model aimed at standardizing the clinical nursing process,reducing the wastage of medical resources,and improving the quality of medical services.AIM To analyze the value of a precise rehabilitation nursing model for chronic disease management in patients with cerebral infarction.METHODS Patients(n=124)admitted to our hospital with cerebral infarction between November 2019 and November 2021 were enrolled as the study subjects.The random number table method was used to divide them into a conventional nursing intervention group(n=61)and a model nursing intervention group(n=63).Changes in the nursing index for the two groups were compared after conventional nursing intervention and precise rehabilitation intervention nursing for chronic disease management.RESULTS Compared with the conventional intervention group,the model intervention group had a shorter time to clinical symptom relief(P<0.05),lower Hamilton Anxiety Scale and Hamilton Depression Scale scores,a lower incidence of total complications(P<0.05),a higher disease knowledge mastery rate,higher safety and quality,and a higher overall nursing satisfaction rate(P<0.05).CONCLUSION The precision rehabilitation nursing model for chronic disease management improves the clinical symptoms of patients with cerebral infarction,reducing the incidence of total complications and improving the clinical outcome of patients,and is worthy of application in clinical practice.
基金supported by the Ministry of Finance of the Republic of Indonesia that provides Beasiswa Unggulan Dosen Indonesia (BUDI) scholarships through the Financial Fund Management Institution。
文摘Jeneberang watershed is vital,particularly for people living in Gowa Regency(South Sulawesi Province,Indonesia),who benefit from its many advantages.Landslides and floods occur every year in the Jeneberang watershed,so it is imperative to understand the socio-economic vulnerability of this region.This research aims to identify the vulnerability level of the Jeneberang watershed so that the government can prioritize areas with high vulnerability level and formulate effective strategies to reduce these the vulnerability.Specifically,this study was conducted in 12 districts located in the Jeneberang watershed.The primary data were collected from questionnaires completed by community members,community leaders,and various stakeholders,and the secondary data were from the Landsat satellite imagery in 2020,the Badan Push Statistic of Gowa Regency,and some governmental agencies.The socio-economic vulnerability variables were determined using the Multiple Criteria Decision Analysis(MCDA)method,and each variable was weighted and analyzed using the Geographical Information System(GIS).The study reveals that the levels of socio-economic vulnerability are affected by variables such as population density,vulnerable groups(disabled people,elderly people,and young people),road network and settlement,percentage of poor people,and productive land area in the Jeneberang watershed.Moreover,all of the 12 districts in the Jeneberang watershed are included in the medium vulnerability level,with the mean percentage of socio-economic vulnerability around 50.92%.The socio-economic vulnerability of Bajeng,Pallangga,and Somba Opu districts is categorized at high level,the socio-economic vulnerability of Bungaya,Parangloe,and Tombolo Pao districts is classified as medium level,and the remaining 6 districts(Barombong,Bontolempangan,Bontomarannu,Manuju,Parigi,and Tinggimoncong)are ranked as low socio-economic vulnerability.This study can help policy-makers to formulate strategy that contributes to the protection of biodiversity and sustainable development of the Jeneberang watershed,while improving disaster resilience and preparedness of the watershed.